Skip to main content

John George McHutchison

Adjunct Professor in the Department of Medicine
Medicine, Gastroenterology
Box 3850 Med Ctr, Durham, NC 27710
Duke Clinical Research Institute, 2400 Pratt Street, Room 8003, Durham, NC 27705

Current Appointments & Affiliations


Adjunct Professor in the Department of Medicine · 2019 - Present Medicine, Gastroenterology, Medicine

Recent Publications


Farglitazar lacks antifibrotic activity in patients with chronic hepatitis C infection.

Journal Article Gastroenterology · April 2010 BACKGROUND & AIMS: Farglitazar (GI262570), an insulin-sensitizing agent, selectively binds and activates peroxisome proliferator-activated receptor gamma (PPARgamma) and inhibits stellate cell activation. We evaluated its antifibrotic effect in patients wi ... Full text Link to item Cite

Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection.

Journal Article N Engl J Med · August 6, 2009 BACKGROUND: Treatment guidelines recommend the use of peginterferon alfa-2b or peginterferon alfa-2a in combination with ribavirin for chronic hepatitis C virus (HCV) infection. However, these regimens have not been adequately compared. METHODS: At 118 sit ... Full text Link to item Cite

Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection.

Journal Article N Engl J Med · April 30, 2009 BACKGROUND: Current therapy for chronic hepatitis C virus (HCV) infection is effective in less than 50% of patients infected with HCV genotype 1. Telaprevir, a protease inhibitor specific to the HCV nonstructural 3/4A serine protease, rapidly reduced HCV R ... Full text Link to item Cite
View All Publications

Recent Grants


CTSA UL

ResearchCo-Director · Awarded by National Institutes of Health · 2006 - 2012

Coordinating Center for DILIN

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2003 - 2008

View All Grants

Education, Training & Certifications


University of Melbourne (Australia) · 1981 M.B.B.S.