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Megan Elizabeth Bowles Clowse

Professor of Medicine
Medicine, Rheumatology and Immunology
Duke Box 3535, Durham, NC 27710
Baker House 07, Duke South, Trent Drive, Durham, NC 27710

Research Interests


Rheumatic Disease in Pregnancy
Medically-complicated pregnancy and Obstetric Medicine
Lupus


Selected Grants


Advancing Reproductive Rheumatology through Research Mentoring

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2029

Improving patient-provider communication and medication adherence in systemic lupus erythematosus

ResearchCo Investigator · Awarded by National Institutes of Health · 2023 - 2028

Improving Quality of Life in SLE by Stratified Personalized Health Planning

ResearchPrincipal Investigator · Awarded by Department of Defense · 2022 - 2026

Optimal Dosing for Biologic Agents in Obese Patients with Rheumatoid and Juvenile Arthritis

ResearchAdvisor · Awarded by National Institutes of Health · 2020 - 2025

Biomarkers of Pregnancy Complications in women with Rheumatic Disease

ResearchPrincipal Investigator · Awarded by GlaxoSmithKline · 2021 - 2025

Development and preliminary validation of a patient-reported measure of systemic lupus erythematosus disease activity

ResearchCo Investigator · Awarded by University of California - San Francisco · 2022 - 2025

Biomarkers to distinguish between Type 1 and 2 SLE activity

ResearchCo-Principal Investigator · Awarded by Exagen , Inc. · 2020 - 2024

Moving the ACR's Reproductive Health Guidelines into Practice

ResearchPrincipal Investigator · Awarded by Rheumatology Research Foundation · 2021 - 2024

Mechanisms of Pain in Systemic Lupus Erythematosus

ResearchCo-Principal Investigator · Awarded by Lupus Research Alliance · 2023 - 2024

Lysosome Defects and the Accumulation of Immune Complexes in Human Lupus - R01 Sub

ResearchCo Investigator · Awarded by University of North Carolina - Chapel Hill · 2019 - 2024

Pfizer QI Telehealth in Rheumatology

ResearchCo Investigator · Awarded by Pfizer, Inc. · 2020 - 2023

Lupus Learning Lab

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by AstraZeneca Pharmaceuticals, LP · 2022 - 2023

A novel approach to measuring and managing chronic pain, fatigue, and depression in systemic lupus erythematosus.

Clinical TrialPrincipal Investigator · Awarded by Pfizer, Inc. · 2019 - 2022

EHR-based LongItudinal Cohort to Explore Pregnancy OuTComes in SLE (ELIPTCL)

ResearchPrincipal Investigator · Awarded by Northwestern University · 2020 - 2022

Harnessing PCORnet to Study Comparative Effectiveness and Safety of Biologic Treatments

ResearchPrincipal Investigator · Awarded by University of Alabama at Birmingham · 2018 - 2020

Pregnancies in women with Lupus in the Carolinas Collaborative (PLiCC) Cohort

ResearchPrincipal Investigator · Awarded by Global Healthy Living Foundation · 2018 - 2019

University of Pennsylvania to Duke Subaward for U54 Grant

ResearchPrincipal Investigator · Awarded by University of Pennsylvania · 2014 - 2019

ASPIRE - Causes of comorbid infertility among women with rheumatoid arthritis

ResearchPrincipal Investigator · Awarded by Pfizer, Inc. · 2014 - 2018

A Retrospective Review of Treatments in Pregnant Psoriatic Arthritis Patients

ResearchPrincipal Investigator · Awarded by Janssen Scientific Affairs, LLC. · 2015 - 2017

Optimizing Lupus Management in Pregnancy

ResearchPrincipal Investigator · Awarded by Agency for Healthcare Research and Quality · 2015 - 2017

Training Program in Inflammatory and Immunological Diseases

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1980 - 2017

Determinants of ANA Expression in Patients with SLE

ResearchInvestigator · Awarded by Lupus Research Institute · 2015 - 2017

International Conference on Reproduction, Pregnancy, and Rheumatic Disease

ConferencePrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2017

Fuller - Health Professional Online Education Grant

FellowshipPrincipal Investigator · Awarded by Rheumatology Research Foundation · 2014 - 2015

Microparticles as a Source of Nuclear Antigens in Systemic Lupus Erythematosus

ResearchCo Investigator · Awarded by National Institutes of Health · 2009 - 2012

External Relationships


  • MotherToBaby
  • RheumNow
  • UCB Pharma
  • UpToDate, Inc

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.