Journal ArticleJ Am Geriatr Soc · August 2019
OBJECTIVES: Older adults who undergo kidney transplantation (KT) are living longer with a functioning graft and are at risk for age-related adverse events including fractures. Understanding recipient, transplant, and donor factors and the outcomes associat ...
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Journal ArticleClin J Am Soc Nephrol · December 7, 2015
BACKGROUND AND OBJECTIVES: Patients of all ages undergoing hemodialysis (HD) have a high prevalence of cognitive impairment and worse cognitive function than healthy controls, and those with dementia are at high risk of death. Frailty has been associated w ...
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Journal ArticleJ Am Geriatr Soc · October 2015
OBJECTIVES: To understand the natural history of frailty after an aggressive surgical intervention, kidney transplantation (KT). DESIGN: Prospective cohort study (December 2008-March 2014). SETTING: Baltimore, Maryland. PARTICIPANTS: Kidney transplantation ...
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Journal ArticleBMC Geriatr · April 24, 2015
BACKGROUND: Frailty, a validated measure of physiologic reserve, predicts adverse health outcomes among adults with end-stage renal disease. Frailty typically is not measured clinically; instead, a surrogate-perceived frailty-is used to inform clinical dec ...
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Journal ArticleBMC Nephrol · April 9, 2015
BACKGROUND: Disparities in access to kidney transplantation (KT) remain inadequately understood and addressed. Detailed descriptions of patient attitudes may provide insight into mechanisms of disparity. The aims of this study were to explore perceptions o ...
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Journal ArticleTransplantation · April 2015
BACKGROUND: Mycophenolate mofetil (MMF) side effects often prompt dose reduction or discontinuation, and this MMF dose reduction (MDR) can lead to rejection and possibly graft loss. Unfortunately, little is known about what factors might cause or contribut ...
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Journal ArticleAm J Transplant · January 2015
We have previously described strong associations between frailty, a measure of physiologic reserve initially described and validated in geriatrics, and early hospital readmission as well as delayed graft function. The goal of this study was to estimate its ...
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Journal ArticleJ Am Soc Nephrol · December 2014
Because informed consent requires discussion of alternative treatments, proper consent for dialysis should incorporate discussion about other renal replacement options including kidney transplantation (KT). Accordingly, dialysis providers are required to i ...
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Journal ArticleJ Am Geriatr Soc · December 2014
OBJECTIVES: To estimate mortality and death-censored graft loss according to year of kidney transplant (KT) between 1990 and 2011. DESIGN: Cohort study. SETTING: The Scientific Registry of Transplant Recipients (SRTR). PARTICIPANTS: KT recipients aged 65 a ...
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Journal ArticleTransplantation · November 15, 2014
BACKGROUND: Live donor kidney transplantation (LDKT) remains underutilized, partly resulting from the challenges many patients face in asking someone to donate. Actual and perceived kidney transplantation (KT) knowledge are potentially modifiable factors t ...
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Journal ArticleClin J Am Soc Nephrol · November 7, 2014
BACKGROUND AND OBJECTIVES: Disparities in kidney transplantation remain; one mechanism for disparities in access to transplantation (ATT) may be patient-perceived concerns about pursuing transplantation. This study sought to characterize prevalence of pati ...
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Journal ArticleJ Am Geriatr Soc · May 2014
OBJECTIVES: To explore whether disparities in age and sex in access to kidney transplantation (KT) originate at the time of prereferral discussions about KT. DESIGN: Cross-sectional survey. SETTING: Outpatient dialysis centers in Maryland (n = 26). PARTICI ...
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Journal ArticleClin Transplant · April 2014
Maximizing deceased donation rates can decrease the organ shortage. Non-transplant physicians play a critical role in facilitating conversion of potential deceased donors to actual donors, but studies suggest that physicians lack knowledge about the organ ...
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Journal ArticleJ Acquir Immune Defic Syndr · December 15, 2013
BACKGROUND: HIV and hepatitis C virus (HCV) infections may increase interleukin-6 (IL-6) and C-reactive protein (CRP). However, relationships between inflammatory biomarkers, chronic viral infections, clinical factors, and behavioral factors remain poorly ...
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Journal ArticleBMC Nephrol · October 16, 2013
BACKGROUND: Patients undergoing hemodialysis are at high risk of falls, with subsequent complications including fractures, loss of independence, hospitalization, and institutionalization. Factors associated with falls are poorly understood in this populati ...
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Journal ArticleAm J Transplant · August 2013
Early hospital readmission (EHR) after kidney transplantation (KT) is associated with increased morbidity and higher costs. Registry-based recipient, transplant and center-level predictors of EHR are limited, and novel predictors are needed. We hypothesize ...
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Journal ArticleJ Am Geriatr Soc · June 2013
OBJECTIVES: To quantify the prevalence of frailty in adults of all ages undergoing chronic hemodialysis, its relationship to comorbidity and disability, and its association with adverse outcomes of mortality and hospitalization. DESIGN: Prospective cohort ...
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Journal ArticleAIDS Care · 2012
This paper explores how perceived stigma and layered stigma related to injection drug use and being HIV-positive influence the decision to disclose one's HIV status to family and community and experiences with stigma following disclosure among a population ...
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Journal ArticleClin Infect Dis · December 2011
BACKGROUND: Despite an increasing burden of age-associated non-AIDS outcomes, few studies have investigated the prevalence or correlates of multimorbidity among aging human immunodeficiency virus (HIV)-infected and epidemiologically comparable at-risk popu ...
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Journal ArticleAIDS Behav · January 2011
Sexual violence has been shown to increase women's risk of HIV infection. India is a country where the HIV epidemic is growing among women and intimate partner violence (IPV) is pervasive. This study examined prevalence of and factors associated with force ...
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Journal ArticleAIDS Educ Prev · December 2010
The full impact of secondary stigma (stigma directed at family) on an HIV-positive individual is unknown. This qualitative research explores perceptions of secondary stigma in the Vietnamese context and its influence on the ways in which an injection drug ...
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Journal ArticleSoc Sci Med · October 2010
With an estimated 2.5 million people living with HIV/AIDS, India has the third highest number of HIV-infected people in the world. Despite reductions in prevalence among the general population, the percentage of all infections occurring among Indian women ...
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Journal ArticleAIDS Care · August 2008
Survey questionnaires and focus group discussions were used to investigate the association between a female participant's acceptance and her perception of her male partner's acceptance of an intravaginal gel as a prototype microbicide. Women who perceived ...
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