Mehri Sadri McKellar
Associate Professor of Medicine
Current Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2017
Contact Information
- Duke Box 102359, Durham, NC 27710
- Rm 175, Hanes House, Box 102359, Durham, NC 27710
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mehri.mckellar@duke.edu
(919) 613-6129
- Background
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Education, Training, & Certifications
- Infectious Diseases Fellow, Medicine, University of Utah 2003 - 2006
- Resident, Medicine, University of Utah 2000 - 2003
- M.D., University of Arizona 2000
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Duke Appointment History
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2016 - 2017
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2008 - 2016
- Instructor, Temporary in the Department of Medicine, Medicine, Infectious Diseases, Medicine 2008
- Recognition
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In the News
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DEC 7, 2018 Duke Research Blog
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- Expertise
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Global Scholarship
- Research
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Selected Grants
- Modeling the effects of chronic marijuana use on neuroinflammation and HIV-related neuronal injury awarded by National Institutes of Health 2020 - 2025
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2025
- GS - US - 380-5310 awarded by Gilead Sciences, Inc. 2019 - 2022
- Ryan White HIV/AIDS Program Part D Coordinated HIV Services and Access to Research for Women, Infants, Children, and Youth (WICY) in Central North Carolina awarded by Health Resources and Service Administration 2010 - 2022
- STYLE 2.0 awarded by Health Resources and Service Administration 2018 - 2021
- Ryan White HIV/AIDS Program Part D Support Services awarded by New Hanover Regional Medical Center 2015 - 2021
- Regional AIDS Education and Training Centers awarded by Vanderbilt University Medical Center 2015 - 2021
- A Multi-arm Phase 3 Randomized Placebo Controlled Double Blind Clnical Trial to Investigate the Efficacy and Safety of BMS-663068 in Heavily Treatment Experienced Subjects Infected with Multi-drug Resistant HIV-1 awarded by ViiV Healthcare 2015 - 2021
- IGHID 11417 - PHI 05 - The Safety and Efficacy of Fixed Dose Combination Dolutegravir/Abacavir/Lamivudine Initiated During Acute HIV Infection: Impact on the Latent HIV Reservoir and Long-Term Immunologic Effect awarded by University of North Carolina - Chapel Hill 2015 - 2021
- Choosing Life: Empowerment Action! Results! (CLEAR) and Integrated Targeted Testing Services (ITTS) awarded by NC DHHS 2016 - 2021
- Randomized study to evaluate Tocilizumab in patients with severe COVID-19 pneumonia (WA42380) awarded by Genentech, Inc. 2020 - 2021
- Ryan White Part B Region 7 Network of Care awarded by NC Dept of Health and Human Services 2016 - 2021
- Housing Opportunities for Persons with AIDS- Region Six awarded by NC Dept of Health and Human Services 2016 - 2020
- Housing Opportunities for Persons with AIDS- Region Seven awarded by NC Department of Health and Human Services 2015 - 2020
- BIKTARVY- GS-US-380-4580 awarded by Gilead Sciences, Inc. 2018 - 2020
- Bringing PrEP to Campus: Examining Strategies for PrEP Delivery to Historically Black College and Universities (HBCU) awarded by National Institutes of Health 2005 - 2020
- "A Phase 3b Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of E/C/F/TAF Fixed Dose Combination (FDC) in HIV-1 Infected Subjects on Chronic Hemodialysis [GS-US-292-1825] awarded by Gilead Sciences, Inc. 2016 - 2020
- GS-US-380-4030 awarded by Gilead Sciences, Inc. 2017 - 2019
- Integrated Targeted Testing Services (ITTS) awarded by Durham County Health Department 2018 - 2019
- Substance Abuse Center (SAC) awarded by Wake County Human Services 2016 - 2019
- Gilead - GS-380-1878 awarded by Gilead Sciences, Inc. 2016 - 2019
- GS-US-380-1961 awarded by Gilead Sciences, Inc. 2016 - 2019
- HIV Early Intervention Testing awarded by Alliance Behavioral Healthcare 2016 - 2018
- GS-US-380-1489 awarded by Gilead Sciences, Inc. 2016 - 2018
- Gilead - GS - US - 380-1844 awarded by Gilead Sciences, Inc. 2016 - 2017
- Phase 3 Open-Label Stdy to Eval Switch Opt Stable Antiretro Reg Cont Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults awarded by Gilead Sciences, Inc. 2013 - 2017
- GS-US-380-1490 awarded by Gilead Sciences, Inc. 2016 - 2017
- Phase 3, 2-part Study to Eval Efficacy of Tenofovir Alafenamide vs Placebo Added to Failing Regimen Followed by Treatment with Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in HIV-1 Positive Antiretroviral Treatment-Experienced Adults awarded by Gilead Sciences, Inc. 2013 - 2016
- HIV and Asthma in the Post- ART Era awarded by National Institutes of Health 2014 - 2016
- Ryan White Region 6 Network of Care awarded by Wake County Human Services 2015 - 2016
- Substance Abuse Center-5 (SAC-5): Counseling, Testing and Referral in Durham, Caswell, Orange, Person and Wake awarded by NC DHHS 2015 - 2016
- The Youth Education and Prevention (Y.E.P.) Network (Ready-To-Respond Initiative) awarded by Department of Health and Human Services 2010 - 2016
- Bundled Testing and Patient navigation awarded by Cape Fear Memorial Foundation 2014 - 2015
- HIV Early Intervention Testing awarded by Alliance Behavioral Healthcare 2014 - 2015
- Substance Abuse Center-5 (SAC-5): Counseling, Testing and Referral in Durham, Caswell, Orange, Person and Wake awarded by NC DHHS 2014 - 2015
- Housing Opportunities for Persons with AIDS awarded by NC Department of Health and Human Services 2014 - 2015
- Housing Opportunities for Persons with AIDS awarded by NC Dept of Health and Human Services 2014 - 2015
- Ryan White Part B Region 7 Network of Care awarded by NC Department of Health and Human Services 2014 - 2015
- Healthy Relationships: Region Seven Prevention for Positives awarded by NC DHHS 2014
- Substance Abuse Center-5 (SAC-5): Counseling, Testing and Referral in Durham, Caswell, Orange, Person and Wake awarded by NC DHHS 2013 - 2014
- FirstSigns-Integration of Prevention in Primary Care Through Training, Testing, and Education awarded by Substance Abuse and Mental Health Services Administration 2005 - 2011
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External Relationships
- Gilead Sciences, Inc.
- Thera Technologies
- Viiv (GlaxoSmithKline)
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Towe, Sheri L., Catherine A. Sullivan, Mehri S. McKellar, and Christina S. Meade. “Examining the Potential of Pre-exposure Prophylaxis (PrEP) for HIV Prevention in a Community Sample of Persons Who Use Stimulants Living in the Southern United States.” Aids Behav, August 5, 2020. https://doi.org/10.1007/s10461-020-02987-y.Full Text Link to Item
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Zhang, Helen L., Bhavini Murthy, Barbara Johnston, Marissa Mortiboy, Jiewei Wu, Gregory P. Samsa, Arlene C. Seña, and Mehri S. McKellar. “Public Awareness of HIV Pre-Exposure Prophylaxis in Durham, North Carolina: Results of a Community Survey.” N C Med J 80, no. 1 (January 2019): 7–11. https://doi.org/10.18043/ncm.80.1.7.Full Text Link to Item
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Eron, Joseph J., Jean-Daniel Lelievre, Robert Kalayjian, Jihad Slim, Anson K. Wurapa, Jeffrey L. Stephens, Cheryl McDonald, et al. “Safety of elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide in HIV-1-infected adults with end-stage renal disease on chronic haemodialysis: an open-label, single-arm, multicentre, phase 3b trial.” Lancet Hiv, December 13, 2018. https://doi.org/10.1016/S2352-3018(18)30296-0.Full Text Link to Item
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McGee, Kara S., Nwora Lance Okeke, Christopher B. Hurt, and Mehri S. McKellar. “Canary in the Coal Mine? Transmitted Mutations Conferring Resistance to All Integrase Strand Transfer Inhibitors in a Treatment-Naive Patient.” Open Forum Infect Dis 5, no. 11 (November 2018): ofy294. https://doi.org/10.1093/ofid/ofy294.Full Text Open Access Copy Link to Item
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Safeek, Rachel H., Katherine S. Hall, Felipe Lobelo, Carlos Del Rio, Audrey L. Khoury, Tammy Wong, Miriam C. Morey, and Mehri S. McKellar. “Low Levels of Physical Activity Among Older Persons Living with HIV/AIDS Are Associated with Poor Physical Function.” Aids Res Hum Retroviruses 34, no. 11 (November 2018): 929–35. https://doi.org/10.1089/AID.2017.0309.Full Text Link to Item
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Mitchell, John T., Sara LeGrand, Lisa B. Hightow-Weidman, Mehri S. McKellar, Angela Dm Kashuba, Mackenzie Cottrell, Tony McLaurin, Goutam Satapathy, and F Joseph McClernon. “Smartphone-Based Contingency Management Intervention to Improve Pre-Exposure Prophylaxis Adherence: Pilot Trial.” Jmir Mhealth Uhealth 6, no. 9 (September 10, 2018): e10456. https://doi.org/10.2196/10456.Full Text Link to Item
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Thaden, Joshua T., Monica Gandhi, Hideaki Okochi, Christopher B. Hurt, and Mehri S. McKellar. “Seroconversion on preexposure prophylaxis: a case report with segmental hair analysis for timed adherence determination.” Aids 32, no. 9 (June 1, 2018): F1–4. https://doi.org/10.1097/QAD.0000000000001825.Full Text Link to Item
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Clement, Meredith E., Jessica Seidelman, Jiewei Wu, Kareem Alexis, Kara McGee, N Lance Okeke, Gregory Samsa, and Mehri McKellar. “An educational initiative in response to identified PrEP prescribing needs among PCPs in the Southern U.S.” Aids Care 30, no. 5 (May 2018): 650–55. https://doi.org/10.1080/09540121.2017.1384534.Full Text Link to Item
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Okeke, Nwora Lance, Meredith E. Clement, Mehri S. McKellar, and Jason E. Stout. “Health Care Utilization Behaviors Predict Disengagement From HIV Care: A Latent Class Analysis.” Open Forum Infect Dis 5, no. 5 (May 2018): ofy088. https://doi.org/10.1093/ofid/ofy088.Full Text Link to Item
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Clement, Meredith E., Nwora L. Okeke, Terry Munn, Miguel Hunter, Kareem Alexis, Amy Corneli, Arlene C. Seña, Kara McGee, and Mehri S. McKellar. “Partnerships Between a University-Affiliated Clinic and Community-Based Organizations to Reach Black Men Who Have Sex With Men for PrEP Care.” J Acquir Immune Defic Syndr 77, no. 2 (February 1, 2018): e25–27. https://doi.org/10.1097/QAI.0000000000001577.Full Text Link to Item
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Zhang, Helen L., Sarah K. Rhea, Christopher B. Hurt, Victoria L. Mobley, Heidi Swygard, Arlene C. Seña, and Mehri S. McKellar. “HIV Preexposure Prophylaxis Implementation at Local Health Departments: A Statewide Assessment of Activities and Barriers.” J Acquir Immune Defic Syndr 77, no. 1 (January 1, 2018): 72–77. https://doi.org/10.1097/QAI.0000000000001546.Full Text Link to Item
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Kort, Daniel N., Gregory P. Samsa, and Mehri S. McKellar. “Sexual orientation differences in HIV testing motivation among college men.” J Am Coll Health 65, no. 3 (April 2017): 223–27. https://doi.org/10.1080/07448481.2016.1277429.Full Text Link to Item
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Khoury, Audrey L., Miriam C. Morey, Tammy C. Wong, Donna Lynn McNeil, Barlett Humphries, Katherine Frankey, Carl F. Pieper, Charles B. Hicks, Kim Huffman, and Mehri S. McKellar. “Diminished physical function in older HIV-infected adults in the Southeastern U.S. despite successful antiretroviral therapy.” Plos One 12, no. 6 (2017): e0179874. https://doi.org/10.1371/journal.pone.0179874.Full Text Link to Item
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Gay, Cynthia L., Sarah J. Willis, Anna B. Cope, JoAnn D. Kuruc, Kara S. McGee, Joe Sebastian, Amanda M. Crooks, et al. “Fixed-dose combination emtricitabine/tenofovir/efavirenz initiated during acute HIV infection; 96-week efficacy and durability.” Aids 30, no. 18 (November 28, 2016): 2815–22. https://doi.org/10.1097/QAD.0000000000001255.Full Text Link to Item
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Okeke, Nwora Lance, Charles B. Hicks, Mehri S. McKellar, Vance G. Fowler, and Jerome J. Federspiel. “History of AIDS in HIV-Infected Patients Is Associated With Higher In-Hospital Mortality Following Admission for Acute Myocardial Infarction and Stroke.” J Infect Dis 213, no. 12 (June 15, 2016): 1955–61. https://doi.org/10.1093/infdis/jiw082.Full Text Link to Item
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Jacobson, Jeffrey M., Jean-Pierre Routy, Seth Welles, Mark DeBenedette, Irina Tcherepanova, Jonathan B. Angel, David M. Asmuth, et al. “Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.” J Acquir Immune Defic Syndr 72, no. 1 (May 1, 2016): 31–38. https://doi.org/10.1097/QAI.0000000000000926.Full Text Link to Item
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Lalezari, Jacob P., Gulam H. Latiff, Cynthia Brinson, Juan Echevarría, Sandra Treviño-Pérez, Johannes R. Bogner, Melanie Thompson, et al. “Safety and efficacy of the HIV-1 attachment inhibitor prodrug BMS-663068 in treatment-experienced individuals: 24 week results of AI438011, a phase 2b, randomised controlled trial.” Lancet Hiv 2, no. 10 (October 2015): e427–37. https://doi.org/10.1016/S2352-3018(15)00177-0.Full Text Link to Item
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Chin, Tammy, Charles Hicks, Gregory Samsa, and Mehri McKellar. “Diagnosing HIV infection in primary care settings: missed opportunities.” Aids Patient Care Stds 27, no. 7 (July 2013): 392–97. https://doi.org/10.1089/apc.2013.0099.Full Text Link to Item
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McKellar, Mehri S., Anna B. Cope, Cynthia L. Gay, Kara S. McGee, Joann D. Kuruc, Melissa G. Kerkau, Christopher B. Hurt, et al. “Acute HIV-1 infection in the Southeastern United States: a cohort study.” Aids Res Hum Retroviruses 29, no. 1 (January 2013): 121–28. https://doi.org/10.1089/aid.2012.0064.Full Text Link to Item
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Mao, Alice, Chidera Obi-Gwacham, Tamsey Hill, Catherine Ryan, Arthur Hendricks, and Mehri McKellar. “Acute Dengue fever causes false-positive reactivity in OraQuick rapid HIV-1/2 antibody test.” J Acquir Immune Defic Syndr 55, no. 5 (December 15, 2010): 641. https://doi.org/10.1097/QAI.0b013e3181f5b291.Full Text Link to Item
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Hoffman, J., J. Van Griensven, R. Colebunders, and M. McKellar. “Role of the CD4 count in HIV management.” Hiv Therapy 4, no. 1 (January 1, 2010): 27–39. https://doi.org/10.2217/hiv.09.58.Full Text
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McKellar, M., and C. Hicks. “HIV testing in the emergency department.” Aids Reader, October 20, 2009.
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Bakeera-Kitaka, S., M. McKellar, C. Snider, A. Kekitiinwa, T. Piloya, P. Musoke, A. Ronald, M. Javanbakht, and R. Colebunders. “Antiretroviral therapy for HIV-1 infected adolescents in Uganda: Assessing the impact on growth and sexual maturation.” Journal of Pediatric Infectious Diseases 3, no. 2 (June 25, 2008): 97–104.
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McKellar, Mehri S., Pam Jongthavorn, and Homayoon Khanlou. “False-positivity of HIV-2 immunoblots in a cohort of elite suppressors infected with HIV-1.” J Acquir Immune Defic Syndr 47, no. 5 (April 15, 2008): 644. https://doi.org/10.1097/QAI.0b013e31815bacfa.Full Text Link to Item
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Callens, Steven F. J., Mehri S. McKellar, and Robert Colebunders. “HIV care and treatment for children in resource-limited settings.” Expert Rev Anti Infect Ther 6, no. 2 (April 2008): 181–90. https://doi.org/10.1586/14787210.6.2.181.Full Text Link to Item
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McKellar, Mehri S., Steven F. J. Callens, and Robert Colebunders. “Pediatric HIV infection: the state of antiretroviral therapy.” Expert Rev Anti Infect Ther 6, no. 2 (April 2008): 167–80. https://doi.org/10.1586/14787210.6.2.167.Full Text Link to Item
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Trachtenberg, Joel D., Andrew D. Kambugu, Mehri McKellar, Fred Semitala, Harriet Mayanja-Kizza, Matthew H. Samore, Allan Ronald, and Merle A. Sande. “The medical management of central nervous system infections in Uganda and the potential impact of an algorithm-based approach to improve outcomes.” Int J Infect Dis 11, no. 6 (November 2007): 524–30. https://doi.org/10.1016/j.ijid.2007.01.014.Full Text Link to Item
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McKellar, Mehri S., Lahar R. Mehta, John E. Greenlee, Devon C. Hale, Gregory C. Booton, Daryl J. Kelly, Paul A. Fuerst, Rama Sriram, and Govinda S. Visvesvara. “Fatal granulomatous Acanthamoeba encephalitis mimicking a stroke, diagnosed by correlation of results of sequential magnetic resonance imaging, biopsy, in vitro culture, immunofluorescence analysis, and molecular analysis.” J Clin Microbiol 44, no. 11 (November 2006): 4265–69. https://doi.org/10.1128/JCM.00649-06.Full Text Link to Item
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McKellar, Mehri S., Maragatha N. Kuchibhatla, Kris Ann K. Oursler, Stephen Crystal, Kathleen M. Akgün, Kristina Crothers, Cynthia L. Gibert, et al. “Racial Differences in Change in Physical Functioning in Older Male Veterans with HIV.” Aids Res Hum Retroviruses 35, no. 11–12 (n.d.): 1034–43. https://doi.org/10.1089/AID.2018.0296.Full Text Link to Item
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Journal Issues
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Paul, Devon W., Nigel B. Neely, Meredith Clement, Isaretta Riley, Mashael Al-Hegelan, Matthew Phelan, Monica Kraft, et al. “Development and validation of an electronic medical record (EMR)-based computed phenotype of HIV-1 infection.” J Am Med Inform Assoc, February 1, 2018. https://doi.org/10.1093/jamia/ocx061.Full Text Link to Item
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- Scholarly, Clinical, & Service Activities
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Outreach & Engaged Scholarship
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