Current Appointments & Affiliations
Associate Professor of Medicine
·
2020 - Present
Medicine, Infectious Diseases,
Medicine
Member of Duke Center for Applied Genomics and Precision Medicine
·
2014 - Present
The Precision Medicine Program,
Medicine
Recent Publications
Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection.
Journal Article Nat Commun · March 10, 2025 Age is among the strongest risk factors for severe outcomes from SARS-CoV-2 infection. Here we describe upper respiratory tract (URT) and peripheral blood transcriptomes of 202 participants (age range of 1 week to 83 years), including 137 non-hospitalized ... Full text Open Access Link to item CiteA Rapid Host Response Blood Test for Bacterial/Viral Infection Discrimination Using a Portable Molecular Diagnostic Platform.
Journal Article Open Forum Infect Dis · January 2025 BACKGROUND: Difficulty discriminating bacterial versus viral etiologies of infection drives unwarranted antibacterial prescriptions and, therefore, antibacterial resistance. METHODS: Utilizing a rapid portable test that measures peripheral blood host gene ... Full text Link to item CiteHarnessing the host response for precision infectious disease diagnosis.
Journal Article Clin Microbiol Rev · December 10, 2024 SUMMARYDetection of the presence of infection and its etiology must be accurate and timely to facilitate appropriate antimicrobial use. Diagnostic strategies that rely solely on pathogen detection often are insufficient due to poor test characteristics, in ... Full text Link to item CiteRecent Grants
Novel Host-Response Biomarker Diagnostics for Invasive Aspergillosis
ResearchMentor · Awarded by National Institutes of Health · 2024 - 2029Host-Pathogen Dynamics in Leptospirosis - P4
ResearchInvestigator · Awarded by University of California - Los Angeles · 2023 - 2028Single Dose Texas 2017 (H3N2) Challenge Study
ResearchInvestigator · Awarded by Darwin Biosciences · 2024 - 2027View All Grants
Education, Training & Certifications
University of Oklahoma ·
2004
M.D.
University of Oklahoma ·
2002
Ph.D.