Current Duke Appointments & Affiliations
Associate Professor of Medicine
·
2020 - Present
Medicine, Infectious Diseases,
Medicine
Member of Duke Center for Applied Genomics and Precision Medicine
·
2014 - Present
The Precision Medicine Program,
Medicine
Recent Scholarly Works
Innate immune responsiveness predicts enhanced cellular immunity and symptomatic disease after controlled human influenza infection.
Journal article Nat Med · July 2026 Controlled human influenza infection studies can uniquely interrogate the early immune factors associated with clinical outcome. In this study, 27 healthy volunteers with low strain-specific serum neutralizing antibody levels were challenged with influenza ... Full text Link to item CiteIt's never lupus: Hemophagocytic lymphohistiocytosis secondary to Ehrlichia chafeensis mimicking a lupus flare.
Journal article Am J Med · June 6, 2026 Full text Link to item CiteGenetics and environment distinctively shape the human immune cell epigenome.
Journal article Nat Genet · February 2026 The epigenome of human immune cells is shaped by both genetics and environmental factors, yet the relative contributions of these influences remain incompletely characterized. Here we use single-nucleus methylation sequencing and assay for transposase-acce ... Full text Link to item CiteRecent Grants
Pediatric Fungal Network STudy of Rare Invasive Fungal DisEases in Immunocompromised Pediatric Patients (PFN-STRIDE)
ResearchPrincipal Investigator · Awarded by Children's Hospital of Philadelphia · 2025 - 2030Novel Host-Response Biomarker Diagnostics for Invasive Aspergillosis
ResearchMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029Host-Pathogen Dynamics in Leptospirosis - P4
ResearchInvestigator · Awarded by University of California - Los Angeles · 2023 - 2028View All Grants
Education
University of Oklahoma ·
2004
M.D.
University of Oklahoma ·
2002
Ph.D.