Current Appointments & Affiliations
Recent Publications
UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer
Journal Article Journal of Experimental & Clinical Cancer Research · October 19, 2023 AbstractBackgroundEpithelial ovarian cancer (EOC) is a global health burden, with the poorest five-year survival rate of the gynecological malignancies du ... Full text CiteABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1.
Journal Article Proceedings of the National Academy of Sciences of the United States of America · April 2023 The hypoxia-inducible factor 1-α (HIF-1α) enables cells to adapt and respond to hypoxia (Hx), and the activity of this transcription factor is regulated by several oncogenic signals and cellular stressors. While the pathways controlling normoxic degradatio ... Full text Open Access CiteDisulfiram Transcends ALDH Inhibitory Activity When Targeting Ovarian Cancer Tumor-Initiating Cells
Journal Article Frontiers in Oncology · March 17, 2022 Epithelial ovarian cancer (EOC) is a global health burden and remains the fifth leading cause of cancer related death in women worldwide with the poorest five-year survival rate of the gynecological malignancies. EOC recurrence is considered to be ... Full text Open Access CiteRecent Grants
Targeting tumor-neural cell interactions to inhibit lung cancer brain metastasis
ResearchResearch Assistant · Awarded by National Institutes of Health · 2021 - 2026View All Grants