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Michael Steven Hershfield

Professor of Medicine
Medicine, Rheumatology and Immunology
Duke Box 3049, Durham, NC 27710
230 Sands Building, Durham, NC 27710

Selected Grants


Non-Registry Agreement Clinical Trial

Clinical TrialPrincipal Investigator · Awarded by Chiesi USA, Inc · 2022 - 2025

Leadiant Monitoring Agreement

ResearchPrincipal Investigator · Awarded by Leadiant Biosciences, Inc. · 2018 - 2023

Leadiant Non-Patient Monitoring Agreement

ResearchPrincipal Investigator · Awarded by Leadiant Biosciences, Inc. · 2019 - 2022

Orchard Agreement

ResearchPrincipal Investigator · Awarded by Orchard Therapeutics · 2019 - 2021

Training Program in Inflammatory and Immunological Diseases

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1980 - 2017

Non-Registry Agreement Clinical Trial

Clinical TrialPrincipal Investigator · Awarded by Chiesi USA, Inc · 2022 - 2025

Leadiant Monitoring Agreement

ResearchPrincipal Investigator · Awarded by Leadiant Biosciences, Inc. · 2018 - 2023

Leadiant Non-Patient Monitoring Agreement

ResearchPrincipal Investigator · Awarded by Leadiant Biosciences, Inc. · 2019 - 2022

Orchard Agreement

ResearchPrincipal Investigator · Awarded by Orchard Therapeutics · 2019 - 2021

Training Program in Inflammatory and Immunological Diseases

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1980 - 2017

PEG-uricase as Therapy for Refractory Gout IND#11274

ResearchPrincipal Investigator · Awarded by Food and Drug Administration · 2004 - 2009

A Lymphoblast Model for Diseases of Purine Metabolism

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1978 - 2007

BIACORE 3000 Biosensor

EquipmentCo Investigator · Awarded by National Institutes of Health · 2002 - 2003

Lymphoblast Model For Diseases Of Purine Metabolism

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1978 - 2002

A Lymphoblast Model For Diseases Of Metabolism

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1992 - 1994

A Lynphoblast Model For Diseases Of Purine Metabolism

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1988 - 1991

A Lymphoblast Model For Diseases Of Purine Metabolism

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1984 - 1985

External Relationships


  • Chiesi USA (Chiesi Global Rare Diseases)
  • Horizon Therapeutics (formerly Horizon Pharmaceuticals)

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.