Current Appointments & Affiliations
W. H. Gardner, Jr. Associate Professor of Biomedical Engineering
·
2023 - Present
Biomedical Engineering,
Pratt School of Engineering
Associate Professor in the Department of Biomedical Engineering
·
2022 - Present
Biomedical Engineering,
Pratt School of Engineering
Associate Professor in Chemistry
·
2022 - Present
Chemistry,
Trinity College of Arts & Sciences
Associate of the Duke Initiative for Science & Society
·
2017 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Recent Publications
Scalable, robust, high-throughput expression & purification of nanobodies enabled by 2-stage dynamic control.
Journal Article Metabolic engineering · September 2024 Nanobodies are single-domain antibody fragments that have garnered considerable use as diagnostic and therapeutic agents as well as research tools. However, obtaining pure VHHs, like many proteins, can be laborious and inconsistent. High level cytoplasmic ... Full text Cite2-Stage microfermentations.
Journal Article Metabolic engineering communications · June 2024 Cell based factories can be engineered to produce a wide variety of products. Advances in DNA synthesis and genome editing have greatly simplified the design and construction of these factories. It has never been easier to generate hundreds or even thousan ... Full text CitePhase separation methods for protein purification: A meta-analysis of purification performance and cost-effectiveness.
Journal Article Biotechnology journal · April 2024 Protein purifications based on phase separations (e.g., precipitation and liquid-liquid extraction) have seen little adoption in commercial protein drug production. To identify barriers, we analyzed the purification performance and economics of 290 phase s ... Full text CiteRecent Grants
University Training Program in Biomolecular and Tissue Engineering
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027Sustainable, Low Cost Production of Biosynthetic 1,2,4-Butanetriol and Butanetriol Trinitrate
ResearchPrincipal Investigator · Awarded by Naval Air Warfare Center · 2021 - 2024Automated CRISPR Enabled DNA Synthesis (CEDS)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2024View All Grants
Education, Training & Certifications
University of Colorado, School of Medicine ·
2007
M.D.
University of Colorado, Boulder ·
2005
Ph.D.