Overview
The primary focus of my research is reactive gas dosimetry. The main body of work has involved using O-labeled nitrogen oxide to perform dosimetric analysis on rodents. O is a radioisotope with a half-life of 2.04 minutes produced in the DUMC cyclotron. This N1502 is exposed to mice, rats guinea pigs and hamsters, either free breathing or on mechanical ventilation. A number of bronchoalveolar lavage studies have been performed demonstrating the high solubility of radiolabeled N02 in the …
Current Appointments & Affiliations
Professor Emeritus of Medicine
·
2012 - Present
Medicine, Pulmonary, Allergy, and Critical Care Medicine,
Medicine
Recent Publications
Development, deployment and usability of a point-of-care decision support system for chronic disease management using the recently-approved HL7 decision support service standard
Journal Article Studies in Health Technology and Informatics · December 1, 2007 Clinical decision support is recognized as one potential remedy for the growing crisis in healthcare quality in the United States and other industrialized nations. While decision support systems have been shown to improve care quality and reduce errors, th ... CiteCellular and connective tissue changes in alveolar septal walls in emphysema.
Journal Article Am J Respir Crit Care Med · December 1999 Emphysema is commonly defined as enlargement of airspaces distal to terminal bronchioles accompanied by destruction of alveolar walls, but without obvious fibrosis. Morphometric techniques were used to correlate changes in components of the alveolar septa ... Full text Link to item CiteMonte Carlo analysis of multi-layer targets for production of 15O.
Journal Article Appl Radiat Isot · 1997 A Monte Carlo simulation code was written to analyze multi-layer targets for production of 15O. The code models beam-particle transport through the target and production and transport of generated radionuclides; it can be used to assess the effects on radi ... Full text Link to item CiteRecent Grants
Ozone Dosimetry Using Radioactive And Stable Isotopes
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1993 - 2000Center For Extrapolation Modeling: Microtoxicology/Microdo
ResearchPrincipal Investigator · Awarded by Environmental Protection Agency · 1992 - 1998View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
1985
M.D.