Overview
Basic-Translational:
1. Systems biology approaches to modeling perioperative cardiovascular injury and adaptation.
2. Mechanisms of perioperative myocardial injury; functional genomics applied to perioperative myocardial injury.
3. Metabolic consequences of perioperative myocardial ischemia-reperfusion injury.
4. Animal models and comparative genomic approaches to study perioperative myocardial ischemia-reperfusion injury.
5. Functional genomics of vein graft disease.
6. Animal models of vein graft disease.
7. Genetic association studies in perioperative medicine.
8. Clinico-genomic risk prediction models for perioperative and long-term adverse cardiovascular outcomes following cardiac surgery.
Clinical:
9. Intraoperative quantification of tissue perfusion by contrast echocardiography.
10. Use of myocardial tissue deformation indices to characterize perioperative ventricular dysfunction/stunning
11. 3-D echocardiographic evaluation of the right ventricle
1. Systems biology approaches to modeling perioperative cardiovascular injury and adaptation.
2. Mechanisms of perioperative myocardial injury; functional genomics applied to perioperative myocardial injury.
3. Metabolic consequences of perioperative myocardial ischemia-reperfusion injury.
4. Animal models and comparative genomic approaches to study perioperative myocardial ischemia-reperfusion injury.
5. Functional genomics of vein graft disease.
6. Animal models of vein graft disease.
7. Genetic association studies in perioperative medicine.
8. Clinico-genomic risk prediction models for perioperative and long-term adverse cardiovascular outcomes following cardiac surgery.
Clinical:
9. Intraoperative quantification of tissue perfusion by contrast echocardiography.
10. Use of myocardial tissue deformation indices to characterize perioperative ventricular dysfunction/stunning
11. 3-D echocardiographic evaluation of the right ventricle
Current Appointments & Affiliations
Associate Professor of Anesthesiology
·
2011 - Present
Anesthesiology, Cardiothoracic,
Anesthesiology
Chief, Division of Cardiac Anesthesiology
·
2013 - Present
Anesthesiology, Cardiothoracic,
Anesthesiology
Recent Publications
Right Ventricle-Pulmonary Artery Coupling in Patients Undergoing Cardiac Interventions.
Journal Article Curr Cardiol Rep · June 2024 PURPOSE OF REVIEW: This review aims to summarize the fundamentals of RV-PA coupling, its non-invasive means of measurement, and contemporary understanding of RV-PA coupling in cardiac surgery, cardiac interventions, and congenital heart disease. RECENT FIN ... Full text Link to item CiteReduce intraoperative albumin utilisation in cardiac surgical patients: a quality improvement initiative.
Journal Article BMJ Open Qual · April 24, 2024 BACKGROUND: Albumin continues to be used routinely by cardiac anaesthesiologists perioperatively despite lack of evidence for improved outcomes. The Multicenter Perioperative Outcomes Group (MPOG) data ranked our institution as one of the highest intraoper ... Full text Link to item CiteThe Role of Recipient Thyroid Hormone Supplementation in Primary Graft Dysfunction After Heart Transplantation: A Propensity-Adjusted Analysis.
Journal Article J Cardiothorac Vasc Anesth · November 2023 OBJECTIVES: To investigate whether recipient administration of thyroid hormone (liothyronine [T3]) is associated with reduced rates of primary graft dysfunction (PGD) after orthotopic heart transplantation. DESIGN: Retrospective cohort study. SETTING: Sing ... Full text Link to item CiteRecent Grants
Timely Response to In-Hospital Deterioration Through Design of Actionable Augmented Intelligence
ResearchPrincipal Investigator · Awarded by Idaho State University · 2020 - 2024Right ventricle adaptive changes in patients undergoing left ventricular assist device implantation
ResearchCollaborator · Awarded by Society of Cardiovascular Anesthesiologists · 2021 - 2023Allergan Botox II
Clinical TrialPrincipal Investigator · Awarded by Allergan, Inc. · 2019 - 2023View All Grants
Education, Training & Certifications
Carol Davila University of Medicine and Pharmacy (Romania) ·
1993
M.D.