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Carmelo Alessio Milano

Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery
Surgery, Cardiovascular and Thoracic Surgery
Box 3043 Med Ctr, Durham, NC
4532A Hosp South - Blue Zone, Durham, NC 27710

Selected Grants


BiVACOR® Total Artificial Heart Early Feasibility Study

Clinical TrialPrincipal Investigator · Awarded by BiVACOR, Inc. · 2024 - 2032

Stimulating Access to Research in Residency (StARR) - NIAID

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2029

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2019 - 2029

Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028

Carmat Total Artificial Heart Early Feasibility Study

Clinical TrialPrincipal Investigator · Awarded by Carmat · 2021 - 2027

Improving Cardiac Transplant Outcomes Through PD-L1 Overexpression Gene Therapy

FellowshipPrincipal Investigator · Awarded by Thoracic Surgery Foundation for Research and Education · 2023 - 2025

Improving Cardiac Transplant Outcomes Through PD-L1 Overexpression Gene Therapy

FellowshipMentor · Awarded by American Heart Association · 2023 - 2024

Antiplatelet Removal and HemocompatIbility EventS with the HeartMate 3 Pump - CDR_971 - ARIES HM3

Clinical TrialPrincipal Investigator · Awarded by St. Jude Medical Inc. · 2020 - 2024

Duke Heart for Honduras

ResearchPrincipal Investigator · Awarded by Thoracic Surgery Foundation for Research and Education · 2023 - 2023

Right ventricle adaptive changes in patients undergoing left ventricular assist device implantation

ResearchCollaborator · Awarded by Society of Cardiovascular Anesthesiologists · 2021 - 2023

HeartMate III IDE Clinical Study Protocol

Clinical TrialPrincipal Investigator · Awarded by Thoratec Corporation · 2014 - 2023

Right Ventricular Metabolic Dysregulation after Surgery for Heart Failure

ResearchAdvisor · Awarded by International Anesthesia Research Society · 2021 - 2023

USE OF THE NUPULSECV iVAS FOR THE TREATMENT OF BRIDGE-TO-TRANSPLANT PATIENTS

Clinical TrialPrincipal Investigator · Awarded by NuPulseCV, Inc. · 2018 - 2023

TSF Every Heartbeat Matters Award

ResearchPrincipal Investigator · Awarded by Thoracic Surgery Foundation for Research and Education · 2020 - 2022

Development of a lightweight, portable, pneumatic drive unit for long-term counterpulsation support

ResearchPrincipal Investigator · Awarded by NuPulseCV, Inc. · 2019 - 2022

HM3 SWIFT Implantation of the HeartMate 3 in Subjects with Heart Failure using Surgical Techniques Other Than Full Median Sternotomy

Clinical TrialPrincipal Investigator · Awarded by Abbott Laboratories · 2021 - 2022

TVVAD Study - Ad Star

Clinical TrialPrincipal Investigator · Awarded by St. Jude Medical Inc. · 2021 - 2022

The Use of Two HeartMate 3¿ pumps (¿Device(s)¿) as a Total Artifact Heart for Chronic Support

ResearchPrincipal Investigator · Awarded by St. Jude Medical Inc. · 2019 - 2022

A prospective, single arm, multi-center clinical study to evaluate the thoracotomy implant technique(Heartware 006)

Clinical TrialPrincipal Investigator · Awarded by HeartWare, Inc · 2015 - 2021

Treatment of Tricuspid Valve Regurgitation in patients undergoing LVAD Implantation study: TVVAD Study

Clinical TrialPrincipal Investigator · Awarded by Medtronic, Inc. · 2018 - 2021

Utilization of Two Heartmate III Pumps as a Total Artificial Heart Replacement

ResearchPrincipal Investigator · Awarded by St. Jude Medical Inc. · 2017 - 2019

Cadaver Implant Studies of PABP

ResearchCo Investigator · Awarded by 3R Life Sciences Taiwan Ltd. · 2018 - 2019

Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients

ResearchPrincipal Investigator · Awarded by Mount Sinai School of Medicine · 2014 - 2019

Role of Mitochondrial Injury in the Pathogenesis of Primary Graft Dysfunction Following Cardiac Transplantation

FellowshipMentor · Awarded by National Institutes of Health · 2016 - 2018

Core Clinical Centers for the CTSN

ResearchCo Investigator · Awarded by National Institutes of Health · 2007 - 2018

Impella RP Support Systems in Patietns with Right Heart Failure

Clinical TrialPrincipal Investigator · Awarded by Abiomed · 2015 - 2017

Expanding the Donor Pool for Heart Transplantation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2014

Proteomic Profiling of Human Heart Tissue Exposed to Microgravity

ResearchCo Investigator · Awarded by National Aeronautics and Space Administration · 2012 - 2013

Autologous EPC lining to improve biocompatibility of circulatory assist devices

ResearchCollaborator · Awarded by National Institutes of Health · 2009 - 2012

PTEN Gene Therapy for Vein Graft Disease

ResearchInvestigator · Awarded by National Institutes of Health · 2009 - 2012

Molecular Basis of Postoperative Delirium in the Elderly

ResearchInvestigator · Awarded by National Institutes of Health · 2003 - 2010

Skeletal Muscle Plasticity Following LVAD Support

ResearchInvestigator · Awarded by National Institutes of Health · 2006 - 2009

PeriOperative Interventional Neuroprotection Trial POINT

ResearchCollaborator · Awarded by National Institutes of Health · 2001 - 2008

Myocardial Gene Transfer during Cardiac Surgery in Swine

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2003 - 2008

Gene Transfer to Prevent Intimal Hyperplasia in a Canine Model of CABG

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2004 - 2006

Myocardial Gene Transfer During Simulated Heart Surgery

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2003 - 2005

Gene Transfer to Alter Transplanted Heart Function

ResearchCo Investigator · Awarded by National Institutes of Health · 1998 - 2004

Gene Transfer to Alter Transplanted Heart Function

ResearchAdministrative Assistant · Awarded by National Institutes of Health · 1998 - 2003

Reduction of Intimal Hyperplasia by a GBY Inhibitor

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2001 - 2003

Tsh Receptor Gene Mutations In Thromboid Neoplasia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1993 - 1994

Tsh Receptor Gene Mutations In Thyroid Neoplasia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1992 - 1994

External Relationships


  • Caripae Biotechnology LLC
  • Thoracic Innovations LLC
  • TransMedics, Inc.

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.