Current Appointments & Affiliations
Paul G. Barash Distinguished Professor of Anesthesiology
·
2023 - Present
Anesthesiology, Critical Care Medicine,
Anesthesiology
Professor in Anesthesiology
·
2023 - Present
Anesthesiology, Critical Care Medicine,
Anesthesiology
Professor in Population Health Sciences
·
2023 - Present
Population Health Sciences,
Basic Science Departments
Recent Publications
Opioid Dose Variation in Cardiac Surgery: A Multicenter Study of Practice.
Journal Article Anesth Analg · May 1, 2025 BACKGROUND: Although high-opioid anesthesia was long the standard for cardiac surgery, some anesthesiologists now favor multimodal analgesia and low-opioid anesthetic techniques. The typical cardiac surgery opioid dose is unclear, and the degree to which p ... Full text Link to item CiteTreatment with Manganese Porphyrin, MnTnBuOE-2-PyP5+, Suppressed the Activation of Macrophages in a Mouse Intracerebral Hemorrhage.
Journal Article Pharmaceuticals (Basel) · April 8, 2025 Background: Manganese porphyrin, MnTnBuOE-2-PyP5+ (BMX-001), improves neurologic deficits in experimental ischemic stroke and has the potential to serve as an adjunct with thrombolysis or thrombectomy in stroke patients. In 10-30% of stroke patients follow ... Full text Link to item CiteProtocol and design of the REPOSE study: a double-blinded, randomised, placebo-controlled trial to evaluate the efficacy of suvorexant to improve postoperative sleep and reduce delirium severity in older patients undergoing non-cardiac surgery.
Journal Article BMJ Open · March 13, 2025 INTRODUCTION: Postoperative delirium occurs in up to 40% of older surgical patients and has been associated with prolonged hospital stays, long-term cognitive impairment and increased 1-year postoperative mortality. Postoperative sleep disturbances may inc ... Full text Link to item CiteRecent Grants
The role of cerebrospinal fluid complement activation in delirium and post-intensive care unit long-term cognitive impairment
ResearchCo-Mentor · Awarded by National Institutes of Health · 2024 - 2029Integrated Detection and Classification of Sepsis via Tensor Methods Using EHR
ResearchCollaborator · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2029Integrated Training in Anesthesiology Research
Inst. Training Prgm or CMECo-Principal Investigator · Awarded by National Institutes of Health · 1996 - 2026View All Grants
Education, Training & Certifications
University of Pavia (Italy) ·
1990
M.D.