Mitchell Eric Horwitz
Professor of Medicine
Allogeneic stem cell transplantation with a focus on the use of umbilical cord blood grafts; Allogenic stem cell transplantation for Sickle Cell Disease; Prevention of acute and chronic graft versus host disease; Improving immune recovery following alternative donor stem cell transplantation using donor graft manipulation.
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2016
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2003
- Affiliate of the Duke Regeneration Center, Regeneration Next Initiative, Basic Science Departments 2021
Contact Information
- 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
- 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
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mitchell.horwitz@duke.edu
(919) 668-1000
- Background
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Education, Training, & Certifications
- Medical Resident, Medicine, Northwestern University 1992 - 1995
- M.D., Rush University 1992
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Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2013 - 2016
- Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2010 - 2013
- Assistant Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2003 - 2009
- Instructor, Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2003
- Recognition
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In the News
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MAY 17, 2023 School of Medicine Magnify -
DEC 5, 2018 Duke Health News
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- Research
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Selected Grants
- A Phase 3, Randomized, Open-Label, Multicenter Study, to Compare T-Guard to Ruxolitinib for the Treatment of Patients with Grade III or IV Steroid-Refractory Acute Graft-Versus-Host Disease (SR-aGVHD) BMT CTN Protocol #2002 awarded by National Marrow Donor Program 2022 - 2027
- BMT CTN 2002 CSPR awarded by Xenikos BV 2022 - 2027
- ALVR106 in Treatment of High-Risk Patients with Respiratory Viral Infections After HSCT awarded by Allovir, Inc. 2021 - 2026
- Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD awarded by National Institutes of Health 2015 - 2026
- A Phase 3, Open-label, Randomized, Multicenter Study of Ravulizumab in Adult and Adolescent Participants who have Thrombotic Microangiopathy (TMA) after Hematopoietic Stem Cell Transplant (HSCT) awarded by Alexion Pharmaceuticals, Inc. 2021 - 2026
- An Open Label Expanded Access Study of Omidubicel, for Allogeneic Transplantation in Patients with Hematological Malignancies awarded by Gamida Cell Ltd 2020 - 2025
- FH8771_Single Arm awarded by Fred Hutchinson Cancer Research Center 2020 - 2025
- CTN1705- Same Day Processing and Storage of Stool Samples for Stool AAT Concentrations, Microbiome and Metabolome studies awarded by National Marrow Donor Program 2021 - 2024
- BMT CTN 1705 ¿ HR aGVHD AAT awarded by National Marrow Donor Program 2019 - 2024
- C10162: Duke University-BMT CTN 1704 protocol study (CHARM) awarded by National Marrow Donor Program 2017 - 2024
- A Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids as Initial Treatment for Chronic Graft Versus Host Disease awarded by Incyte Corporation 2019 - 2024
- Blood and Marrow Transplant Clinical Trials Network awarded by National Institutes of Health 2001 - 2024
- A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell awarded by National Marrow Donor Program 2019 - 2024
- A Phase 2/3, Multicenter, randomized, double-blind, placebo-controlled, study to evaluate the safety and efficacy of Alpha-! Antitrypsin for the Prevention of GVHD awarded by CSL Behring LLC 2019 - 2024
- A Blinded, Prospective Non-Interventional Observational Study for the Evaluation of a GVHD Negative Outcome Score (GNOS) in Matched Unrelated or Haploidentical Hematopoietic Stem Cell Transplant awarded by Washington University in St. Louis 2017 - 2022
- Study Agreement #816977 Related to BMT CTN 1703/1801 Study awarded by National Marrow Donor Program 2019 - 2021
- A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phae III trial of the FLT3 Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients with FLT3-ITD AML BMT CTN Protocol 1506 awarded by Astellas Pharma Inc. 2017 - 2021
- A Multicenter, Randomized, Phase III Registratoin Trial of Transplantation of NiCord, Ex Vivo Expanded, Umbilical Cord Blood-derived, Stem and Progenitor Cells, versus Unmanipulated Umbilical Cord Blood for patients with Hematological Malignancies awarded by Gamida Cell Ltd 2016 - 2021
- A Randomized, Phase II, Multicenter, Open Label, Study Evaluating Sirolimus and Prednisone in Patients with Refined Minnesota Standard Risk, Ann Arbor 1/2 Confirmed Acute Graft-Versus-Host Disease (GMT CTN Protocol 1501 awarded by National Marrow Donor Program 2016 - 2021
- A phase III Randomized Open-Label Multi-Center study of ruxolitinib vs. best available therapy in patients with corticosteroid-refractory chronic graft vs host disease after allogenic stem cell transplantation awarded by Incyte Corporation 2017 - 2019
- Prospective, Phase I/II, randomized clinical study to compare BEGEDINA versus "conventional treatment" for treating steroid resistant acute GvHD. awarded by Adienne SA 2015 - 2019
- Phase III RECRUIT Study CTN 1505 awarded by University of Texas Health Science Center at Houston 2015 - 2017
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External Relationships
- Equillium
- Gamida-Cell, Ltd.
- Talaris
- Vor Biopharma
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Lin, Chenyu, Rachel A. DiCioccio, Tarek Haykal, William C. McManigle, Zhiguo Li, Sarah M. Anand, Jonathan C. Poe, et al. “A Phase I Trial of SYK Inhibition with Fostamatinib in the Prevention and Treatment of Chronic Graft-Versus-Host Disease.” Transplant Cell Ther 29, no. 3 (March 2023): 179.e1-179.e10. https://doi.org/10.1016/j.jtct.2022.12.015.Full Text Link to Item
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Lin, Chenyu, Aurelie Schwarzbach, Jamie Sanz, Pau Montesinos, Patrick Stiff, Suhag Parikh, Claudio Brunstein, et al. “Multicenter Long-Term Follow-Up of Allogeneic Hematopoietic Cell Transplantation with Omidubicel: A Pooled Analysis of Five Prospective Clinical Trials.” Transplantation and Cellular Therapy, February 10, 2023. https://doi.org/10.1016/j.jtct.2023.01.031.Full Text Link to Item
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Saad, Ayman, Alison Loren, Javier Bolaños-Meade, George Chen, Daniel Couriel, Antonio Di Stasi, Areej El-Jawahri, et al. “NCCN Guidelines® Insights: Hematopoietic Cell Transplantation, Version 3.2022.” J Natl Compr Canc Netw 21, no. 2 (February 2023): 108–15. https://doi.org/10.6004/jnccn.2023.0007.Full Text Link to Item
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Lin, Chenyu, Gautam Sajeev, Patrick J. Stiff, Claudio G. Brunstein, Corey Cutler, Guillermo Sanz, Caroline A. Lindemans, et al. “Health-Related Quality of Life Following Allogeneic Hematopoietic Cell Transplantation with Omidubicel versus Umbilical Cord Blood.” Transplantation and Cellular Therapy 29, no. 1 (January 2023): 52.e1-52.e9. https://doi.org/10.1016/j.jtct.2022.09.018.Full Text
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Patel, Pranalee, Mairead Dillon, Donna Niedzwiecki, Mitchell E. Horwitz, and Chris R. Kelsey. “Optimizing Management of the Central Nervous System in Patients with Acute Lymphoblastic Leukemia Undergoing Allogeneic Stem Cell Transplantation.” Adv Radiat Oncol 8, no. 2 (2023): 101082. https://doi.org/10.1016/j.adro.2022.101082.Full Text Link to Item
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Lin, Chenyu, Mitchell E. Horwitz, and Lindsay A. M. Rein. “Leveraging Natural Killer Cell Innate Immunity against Hematologic Malignancies: From Stem Cell Transplant to Adoptive Transfer and Beyond.” Int J Mol Sci 24, no. 1 (December 22, 2022). https://doi.org/10.3390/ijms24010204.Full Text Link to Item
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Katsanis, Emmanuel, Therese Hennig, Jacob E. Robinson, Gwynn Long, Nelson Chao, Mitchell Horwitz, and David Rizzieri. “Revisiting a single day salvage conditioning following graft failure.” Bone Marrow Transplant 57, no. 12 (December 2022): 1845–47. https://doi.org/10.1038/s41409-022-01832-1.Full Text Link to Item
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Lin, Chenyu, Aurelie Schwarzbach, Pau Montesinos, Patrick Stiff, Corey Cutler, Suhag Parikh, Claudio Brunstein, et al. “CT-314 Multicenter Long-Term Follow Up of Allogeneic Hematopoietic Stem Cell Transplantation With Omidubicel: A Pooled Analysis of Five Prospective Clinical Trials.” Clin Lymphoma Myeloma Leuk 22 Suppl 2 (October 2022): S442. https://doi.org/10.1016/S2152-2650(22)01662-7.Full Text Link to Item
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Lin, Chenyu, Gautam Sajeev, Patrick Stiff, Claudio Brunstein, Corey Cutler, Guillermo Sanz, Caroline Lindemans, et al. “CT-039 Health-Related Quality of Life Following Allogeneic Hematopoietic Stem Cell Transplantation With Omidubicel Versus Standard Umbilical Cord Blood.” Clin Lymphoma Myeloma Leuk 22 Suppl 2 (October 2022): S432–33. https://doi.org/10.1016/S2152-2650(22)01643-3.Full Text Link to Item
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DeZern, Amy E., Mary Eapen, Juan Wu, Julie-An Talano, Melhem Solh, Blachy J. Dávila Saldaña, Chatchada Karanes, et al. “Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase 2 trial.” Lancet Haematol 9, no. 9 (September 2022): e660–69. https://doi.org/10.1016/S2352-3026(22)00206-X.Full Text Link to Item
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Lew, Meagan V., Yi Ren, Yen P. Lowder, Sharareh Siamakpour-Reihani, Sendhilnathan Ramalingam, Kristi M. Romero, Jillian C. Thompson, et al. “Geriatric Assessment Reveals Actionable Impairments in Hematopoietic Stem Cell Transplantation Candidates Age 18 to 80 Years.” Transplant Cell Ther 28, no. 8 (August 2022): 498.e1-498.e9. https://doi.org/10.1016/j.jtct.2022.05.018.Full Text Link to Item
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Brunstein, Claudio G., Paul V. O’Donnell, Brent Logan, Peter Dawson, Luciano Costa, Corey Cutler, Michael Craig, et al. “Impact of Center Experience with Donor Type on Outcomes: A Secondary Analysis, Blood and Marrow Transplant Clinical Trials Network 1101Open for Accrual June 2012Open for Accrual June 2012.” Transplantation and Cellular Therapy 28, no. 7 (July 2022): 406.e1-406.e6. https://doi.org/10.1016/j.jtct.2022.03.024.Full Text
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Wolfe, Heather R., Mitchell E. Horwitz, and Lindsay A. M. Rein. “The Use of Allogeneic Hematopoietic Stem Cell Transplantation in Primary Myelofibrosis.” J Pers Med 12, no. 4 (April 2, 2022). https://doi.org/10.3390/jpm12040571.Full Text Link to Item
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Sung, Anthony D., Vinay K. Giri, Helen Tang, Krista Rowe Nichols, Meagan V. Lew, Lauren Bohannon, Yi Ren, et al. “Home-Based Hematopoietic Cell Transplantation in the United States.” Transplant Cell Ther 28, no. 4 (April 2022): 207.e1-207.e8. https://doi.org/10.1016/j.jtct.2022.01.015.Full Text Link to Item
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Koning, Coco de, Weiyang Tao, Amelia Lacna, Karin van Veghel, Mitchell E. Horwitz, Guillermo Sanz, Madan H. Jagasia, et al. “Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation.” Bone Marrow Transplant 56, no. 11 (November 2021): 2826–33. https://doi.org/10.1038/s41409-021-01417-4.Full Text Link to Item
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Horwitz, Mitchell E., Patrick J. Stiff, Corey Cutler, Claudio Brunstein, Rabi Hanna, Richard T. Maziarz, Andrew R. Rezvani, et al. “Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study.” Blood 138, no. 16 (October 21, 2021): 1429–40. https://doi.org/10.1182/blood.2021011719.Full Text Link to Item
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Herrera, Alex F., Kwang Woo Ahn, Carlos Litovich, Yue Chen, Amer Assal, Qaiser Bashir, Ruthee-Lu Bayer, et al. “Autologous and allogeneic hematopoietic cell transplantation for diffuse large B-cell lymphoma-type Richter syndrome.” Blood Adv 5, no. 18 (September 28, 2021): 3528–39. https://doi.org/10.1182/bloodadvances.2021004865.Full Text Link to Item
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Islam, Prioty, Helen Tang, Haesu Jin, Felicia Cao, Lauren M. Bohannon, Yi Ren, Nelson J. Chao, et al. “Female Sex Is Associated with Improved Long-Term Survival Following Allogeneic Hematopoietic Stem Cell Transplantation.” Transplant Cell Ther 27, no. 9 (September 2021): 784.e1-784.e7. https://doi.org/10.1016/j.jtct.2021.06.012.Full Text Link to Item
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Bohannon, Lauren, Helen Tang, Kristin Page, Yi Ren, Sin-Ho Jung, Alexandra Artica, Anne Britt, et al. “Decreased Mortality in 1-Year Survivors of Umbilical Cord Blood Transplant vs. Matched Related or Matched Unrelated Donor Transplant in Patients with Hematologic Malignancies.” Transplantation and Cellular Therapy 27, no. 8 (August 2021): 669.e1-669.e8. https://doi.org/10.1016/j.jtct.2021.05.002.Full Text Open Access Copy
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Ponce, Doris M., Ioannis Politikos, Amin Alousi, Paul A. Carpenter, Filippo Milano, Margaret L. MacMillan, Juliet N. Barker, Mitchell E. Horwitz, and Mitchell E. American Society for Transplantation and Cellular Therapy Cord Blood Special Interest Group. “Guidelines for the Prevention and Management of Graft-versus-Host Disease after Cord Blood Transplantation.” Transplant Cell Ther 27, no. 7 (July 2021): 540–44. https://doi.org/10.1016/j.jtct.2021.03.012.Full Text Link to Item
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Scott, Bart L., Marcelo C. Pasquini, Mingwei Fei, Raphael Fraser, Juan Wu, Steve M. Devine, David L. Porter, et al. “Myeloablative versus Reduced-Intensity Conditioning for Hematopoietic Cell Transplantation in Acute Myelogenous Leukemia and Myelodysplastic Syndromes-Long-Term Follow-Up of the BMT CTN 0901 Clinical Trial.” Transplant Cell Ther 27, no. 6 (June 2021): 483.e1-483.e6. https://doi.org/10.1016/j.jtct.2021.02.031.Full Text Link to Item
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Pabon, Cindy M., Zhiguo Li, Therese Hennig, Carlos de Castro, Jadee L. Neff, Mitchell E. Horwitz, Thomas W. LeBlanc, et al. “Morphologic leukemia-free state in acute myeloid leukemia is sufficient for successful allogeneic hematopoietic stem cell transplant.” Blood Cancer J 11, no. 5 (May 16, 2021): 92. https://doi.org/10.1038/s41408-021-00481-9.Full Text Open Access Copy Link to Item
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Giri, Vinay K., Kristin G. Kegerreis, Yi Ren, Lauren M. Bohannon, Erica Lobaugh-Jin, Julia A. Messina, Anita Matthews, et al. “Chlorhexidine Gluconate Bathing Reduces the Incidence of Bloodstream Infections in Adults Undergoing Inpatient Hematopoietic Cell Transplantation.” Transplant Cell Ther 27, no. 3 (March 2021): 262.e1-262.e11. https://doi.org/10.1016/j.jtct.2021.01.004.Full Text Link to Item
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Racioppi, Alessandro, Tara Dalton, Sendhilnathan Ramalingam, Kristi Romero, Yi Ren, Lauren Bohannon, Consuelo Arellano, et al. “Assessing the Feasibility of a Novel mHealth App in Hematopoietic Stem Cell Transplant Patients.” Transplant Cell Ther 27, no. 2 (February 2021): 181.e1-181.e9. https://doi.org/10.1016/j.jtct.2020.10.017.Full Text Link to Item
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Fuchs, Ephraim J., Paul V. O’Donnell, Mary Eapen, Brent Logan, Joseph H. Antin, Peter Dawson, Steven Devine, et al. “Double unrelated umbilical cord blood vs HLA-haploidentical bone marrow transplantation: the BMT CTN 1101 trial.” Blood 137, no. 3 (January 21, 2021): 420–28. https://doi.org/10.1182/blood.2020007535.Full Text Link to Item
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Maung, Ko K., Benny J. Chen, Ian Barak, Zhiguo Li, David A. Rizzieri, Cristina Gasparetto, Keith M. Sullivan, et al. “Phase I dose escalation study of naive T-cell depleted donor lymphocyte infusion following allogeneic stem cell transplantation.” Bone Marrow Transplant 56, no. 1 (January 2021): 137–43. https://doi.org/10.1038/s41409-020-0991-5.Full Text Link to Item
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Dillon, Laura W., Gege Gui, Brent R. Logan, Mingwei Fei, Jack Ghannam, Yuesheng Li, Abel Licon, et al. “Impact of Conditioning Intensity and Genomics on Relapse After Allogeneic Transplantation for Patients With Myelodysplastic Syndrome.” Jco Precis Oncol 5 (2021). https://doi.org/10.1200/PO.20.00355.Full Text Link to Item
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Ramalingam, Sendhilnathan, Sharareh Siamakpour-Reihani, Lauren Bohannan, Yi Ren, Alexander Sibley, Jeff Sheng, Li Ma, et al. “A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant.” Plos One 16, no. 6 (January 2021): e0252995. https://doi.org/10.1371/journal.pone.0252995.Full Text
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Smith, Patrick, Jillian C. Thompson, Elena Perea, Brian Wasserman, Lauren Bohannon, Alessandro Racioppi, Taewoong Choi, et al. “Clinical and Neuroimaging Correlates of Post-Transplant Delirium.” Biol Blood Marrow Transplant 26, no. 12 (December 2020): 2323–28. https://doi.org/10.1016/j.bbmt.2020.09.016.Full Text Link to Item
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Scaradavou, Andromachi, Scott T. Avecilla, Joann Tonon, Ioannis Politikos, Mitchell E. Horwitz, Joanne Kurtzberg, Filippo Milano, Juliet N. Barker, and Juliet N. American Society for Transplantation and Cellular Therapy Cord Blood Special Interest Group. “Guidelines for Cord Blood Unit Thaw and Infusion.” Biol Blood Marrow Transplant 26, no. 10 (October 2020): 1780–83. https://doi.org/10.1016/j.bbmt.2020.06.018.Full Text Open Access Copy Link to Item
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Foster, Gena G., Michael J. Grant, Samantha M. Thomas, Blake Cameron, Doug Raiff, Kelly Corbet, Gavin Loitsch, Christopher Ferreri, and Mitchell Horwitz. “Treatment with Foscarnet after Allogeneic Hematopoietic Cell Transplant (Allo-HCT) Is Associated with Long-Term Loss of Renal Function.” Biol Blood Marrow Transplant 26, no. 9 (September 2020): 1597–1606. https://doi.org/10.1016/j.bbmt.2020.05.007.Full Text Link to Item
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Fuchs, Ephraim J., Paul V. O’Donnell, Mary Eapen, Brent R. Logan, Joseph H. Antin, Peter Dawson, Steven M. Devine, et al. “Double unrelated umbilical cord blood versus HLA-haploidentical bone marrow transplantation (BMT CTN 1101).” Blood, August 31, 2020. https://doi.org/10.1182/blood.2020007535.Full Text Link to Item
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Saad, Ayman, Marcos de Lima, Sarah Anand, Vijaya Raj Bhatt, Ryan Bookout, George Chen, Daniel Couriel, et al. “Hematopoietic Cell Transplantation, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 18, no. 5 (May 1, 2020): 599–634. https://doi.org/10.6004/jnccn.2020.0021.Full Text Link to Item
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Hourigan, Christopher S., Laura W. Dillon, Gege Gui, Brent R. Logan, Mingwei Fei, Jack Ghannam, Yuesheng Li, et al. “Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease.” J Clin Oncol 38, no. 12 (April 20, 2020): 1273–83. https://doi.org/10.1200/JCO.19.03011.Full Text Link to Item
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Saullo, Jennifer L., Yanhong Li, Julia A. Messina, Jillian Thompson, Tara Dalton, Vinay K. Giri, Shelby D. Reed, et al. “Cytomegalovirus in Allogeneic Hematopoietic Transplantation: Impact on Costs and Clinical Outcomes Using a Preemptive Strategy.” Biol Blood Marrow Transplant 26, no. 3 (March 2020): 568–80. https://doi.org/10.1016/j.bbmt.2019.11.005.Full Text Link to Item
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Maung, Ko, Sendhilnathan Ramalingam, Mohammad Chaudhry, Yi Ren, Sin-Ho Jung, Kristi Romero, Kelly Corbet, et al. “Pre-transplant hepatic steatosis (fatty liver) is associated with chronic graft-vs-host disease but not mortality.” Plos One 15, no. 9 (2020): e0238824. https://doi.org/10.1371/journal.pone.0238824.Full Text Link to Item
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Islam, Prioty, and Mitchell E. Horwitz. “Small-molecule nicotinamide for ex vivo expansion of umbilical cord blood.” Exp Hematol 80 (December 2019): 11–15. https://doi.org/10.1016/j.exphem.2019.11.006.Full Text Link to Item
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Horwitz, Mitchell E. “Intestinal Acute Graft-versus-Host Disease: A Bug Highway to the Bloodstream.” Biol Blood Marrow Transplant 25, no. 8 (August 2019): e250–51. https://doi.org/10.1016/j.bbmt.2019.06.011.Full Text Link to Item
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Cardones, Adela R., Keith M. Sullivan, Cindy Green, Nelson J. Chao, Krista Rowe-Nichols, Lionel L. Bañez, Claude S. Burton, et al. “Interrater Reliability of Clinical Grading Measures for Cutaneous Chronic Graft-vs-Host Disease.” Jama Dermatol 155, no. 7 (July 1, 2019): 833–37. https://doi.org/10.1001/jamadermatol.2018.5459.Full Text Link to Item
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Maung, Ko K., and Mitchell E. Horwitz. “Current and future perspectives on allogeneic transplantation using ex vivo expansion or manipulation of umbilical cord blood cells.” Int J Hematol 110, no. 1 (July 2019): 50–58. https://doi.org/10.1007/s12185-019-02670-6.Full Text Link to Item
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Chen, Yi-Bin, Jennifer Le-Rademacher, Ruta Brazauskas, Deidre M. Kiefer, Mehdi Hamadani, John F. DiPersio, Mark R. Litzow, et al. “Plerixafor alone for the mobilization and transplantation of HLA-matched sibling donor hematopoietic stem cells.” Blood Adv 3, no. 6 (March 26, 2019): 875–83. https://doi.org/10.1182/bloodadvances.2018027599.Full Text Link to Item
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Horwitz, Mitchell E., Stephen Wease, Beth Blackwell, David Valcarcel, Francesco Frassoni, Jaap Jan Boelens, Stefan Nierkens, et al. “Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide.” J Clin Oncol 37, no. 5 (February 10, 2019): 367–74. https://doi.org/10.1200/JCO.18.00053.Full Text Open Access Copy Link to Item
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Spellecy, Ryan, Sergey Tarima, Ellen Denzen, Heather Moore, Sunil Abhyankar, Peter Dawson, Amy Foley, et al. “Easy-to-Read Informed Consent Form for Hematopoietic Cell Transplantation Clinical Trials: Results from the Blood and Marrow Transplant Clinical Trials Network 1205 Study.” Biol Blood Marrow Transplant 24, no. 10 (October 2018): 2145–51. https://doi.org/10.1016/j.bbmt.2018.04.014.Full Text Link to Item
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Micallef, Ivana N., Patrick J. Stiff, Auayporn P. Nademanee, Richard T. Maziarz, Mitchell E. Horwitz, Edward A. Stadtmauer, Jonathan L. Kaufman, et al. “Plerixafor Plus Granulocyte Colony-Stimulating Factor for Patients with Non-Hodgkin Lymphoma and Multiple Myeloma: Long-Term Follow-Up Report.” Biol Blood Marrow Transplant 24, no. 6 (June 2018): 1187–95. https://doi.org/10.1016/j.bbmt.2018.01.039.Full Text Link to Item
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Sullivan, Keith M., Mitchell Horwitz, Ifeyinwa Osunkwo, Nirmish Shah, and John J. Strouse. “Shared Decision-Making in Hematopoietic Stem Cell Transplantation for Sickle Cell Disease.” Biol Blood Marrow Transplant 24, no. 5 (May 2018): 883–84. https://doi.org/10.1016/j.bbmt.2018.04.001.Full Text Link to Item
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Jones, Roy B., Charles Martinez, Navneet S. Majhail, Matthew Prestegaard, Martin Maiers, Mitchell Horwitz, and Krishna Komanduri. “Stem Cell Transplantation and Informatics: Current Considerations.” Biol Blood Marrow Transplant 24, no. 4 (April 2018): 659–65. https://doi.org/10.1016/j.bbmt.2017.12.792.Full Text Link to Item
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Sivaraj, D., W. Bacon, G. D. Long, D. A. Rizzieri, M. E. Horwitz, K. M. Sullivan, Y. Kang, Z. Li, N. J. Chao, and C. Gasparetto. “High-dose BCNU/Melphalan conditioning regimen before autologous stem cell transplantation in newly diagnosed multiple myeloma.” Bone Marrow Transplant 53, no. 1 (January 2018): 34–38. https://doi.org/10.1038/bmt.2017.208.Full Text Link to Item
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Grant, Michael J., and Mitchell E. Horwitz. “HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature.” Case Rep Transplant 2018 (2018): 2376483. https://doi.org/10.1155/2018/2376483.Full Text Open Access Copy Link to Item
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Soiffer, Robert J., Haesook T. Kim, Joseph McGuirk, Mitchell E. Horwitz, Laura Johnston, Mrinal M. Patnaik, Witold Rybka, et al. “Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation.” J Clin Oncol 35, no. 36 (December 20, 2017): 4003–11. https://doi.org/10.1200/JCO.2017.75.8177.Full Text Link to Item
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Huang, Li-Wen, Wendi Bacon, Constance Cirrincione, Bercedis Peterson, Gwynn Long, David Rizzieri, Keith M. Sullivan, et al. “Efficacy and safety of high-dose chemotherapy with autologous stem cell transplantation in senior versus younger adults with newly diagnosed multiple myeloma.” Hematol Oncol 35, no. 4 (December 2017): 752–59. https://doi.org/10.1002/hon.2379.Full Text Link to Item
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Poe, Jonathan C., Wei Jia, Hsuan Su, Sarah Anand, Jeremy J. Rose, Prasanthi V. Tata, Amy N. Suthers, et al. “An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.” Blood 130, no. 19 (November 9, 2017): 2131–45. https://doi.org/10.1182/blood-2017-05-782466.Full Text Link to Item
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Stover, Jessica T., J Ryan Shaw, Maragatha Kuchibhatla, Mitchell E. Horwitz, and Ashley M. Engemann. “Evaluation of Hematopoietic Stem Cell Mobilization Rates with Early Plerixafor Administration for Adult Stem Cell Transplantation.” Biol Blood Marrow Transplant 23, no. 8 (August 2017): 1290–94. https://doi.org/10.1016/j.bbmt.2017.04.007.Full Text Link to Item
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Anand, Sarah, Samantha Thomas, Terry Hyslop, Janet Adcock, Kelly Corbet, Cristina Gasparetto, Richard Lopez, et al. “Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization.” Biol Blood Marrow Transplant 23, no. 7 (July 2017): 1151–57. https://doi.org/10.1016/j.bbmt.2017.04.001.Full Text Link to Item
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Barker, Juliet N., Joanne Kurtzberg, Karen Ballen, Michael Boo, Claudio Brunstein, Corey Cutler, Mitchell Horwitz, et al. “Optimal Practices in Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies.” Biol Blood Marrow Transplant 23, no. 6 (June 2017): 882–96. https://doi.org/10.1016/j.bbmt.2017.03.006.Full Text Open Access Copy Link to Item
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Scott, Bart L., Marcelo C. Pasquini, Brent R. Logan, Juan Wu, Steven M. Devine, David L. Porter, Richard T. Maziarz, et al. “Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.” J Clin Oncol 35, no. 11 (April 10, 2017): 1154–61. https://doi.org/10.1200/JCO.2016.70.7091.Full Text Link to Item
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Sivaraj, Dharshan, Michael M. Green, Zhiguo Li, Anthony D. Sung, Stefanie Sarantopoulos, Yubin Kang, Gwynn D. Long, et al. “Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma.” Biol Blood Marrow Transplant 23, no. 2 (February 2017): 262–68. https://doi.org/10.1016/j.bbmt.2016.11.010.Full Text Link to Item
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Sung, Anthony, and Mitchell Horwitz. “Reply to Strahilevitz and Shapira.” Clin Infect Dis, December 12, 2016. https://doi.org/10.1093/cid/ciw813.Full Text Link to Item
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Sung, Anthony D., Julia A. M. Sung, Samantha Thomas, Terry Hyslop, Cristina Gasparetto, Gwynn Long, David Rizzieri, et al. “Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial.” Clin Infect Dis 63, no. 8 (October 15, 2016): 999–1006. https://doi.org/10.1093/cid/ciw451.Full Text Link to Item
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Green, Michael M. B., Nelson Chao, Saurabh Chhabra, Kelly Corbet, Cristina Gasparetto, Ari Horwitz, Zhiguo Li, et al. “Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.” J Hematol Oncol 9, no. 1 (August 17, 2016): 71. https://doi.org/10.1186/s13045-016-0301-2.Full Text Open Access Copy Link to Item
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Flowers, Christopher R., Luciano J. Costa, Marcelo C. Pasquini, Jennifer Le-Rademacher, Michael Lill, Tsiporah B. Shore, William Vaughan, et al. “Efficacy of Pharmacokinetics-Directed Busulfan, Cyclophosphamide, and Etoposide Conditioning and Autologous Stem Cell Transplantation for Lymphoma: Comparison of a Multicenter Phase II Study and CIBMTR Outcomes.” Biol Blood Marrow Transplant 22, no. 7 (July 2016): 1197–1205. https://doi.org/10.1016/j.bbmt.2016.03.018.Full Text Open Access Copy Link to Item
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Horwitz, Mitchell E. “Ex Vivo Expansion or Manipulation of Stem Cells to Improve Outcome of Umbilical Cord Blood Transplantation.” Curr Hematol Malig Rep 11, no. 1 (February 2016): 12–18. https://doi.org/10.1007/s11899-015-0297-7.Full Text Link to Item
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Anderlini, Paolo, Juan Wu, Iris Gersten, Marian Ewell, Jakob Tolar, Joseph H. Antin, Roberta Adams, et al. “Cyclophosphamide conditioning in patients with severe aplastic anaemia given unrelated marrow transplantation: a phase 1-2 dose de-escalation study.” Lancet Haematol 2, no. 9 (September 2015): e367–75. https://doi.org/10.1016/S2352-3026(15)00147-7.Full Text Link to Item
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Horwitz, Mitchell E., and Francesco Frassoni. “Improving the outcome of umbilical cord blood transplantation through ex vivo expansion or graft manipulation.” Cytotherapy 17, no. 6 (June 2015): 730–38. https://doi.org/10.1016/j.jcyt.2015.02.004.Full Text Link to Item
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Tuchman, Sascha A., Wendi A. Bacon, Li-Wen Huang, Gwynn Long, David Rizzieri, Mitchell Horwitz, John P. Chute, et al. “Cyclophosphamide-based hematopoietic stem cell mobilization before autologous stem cell transplantation in newly diagnosed multiple myeloma.” J Clin Apher 30, no. 3 (June 2015): 176–82. https://doi.org/10.1002/jca.21360.Full Text Link to Item
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Barker, Juliet N., Mingwei Fei, Chatchada Karanes, Mitchell Horwitz, Steven Devine, Tamila L. Kindwall-Keller, Jennifer Holter, et al. “Results of a prospective multicentre myeloablative double-unit cord blood transplantation trial in adult patients with acute leukaemia and myelodysplasia.” Br J Haematol 168, no. 3 (February 2015): 405–12. https://doi.org/10.1111/bjh.13136.Full Text Link to Item
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Kelsey, C. R., J. M. Scott, A. Lane, E. Schwitzer, M. J. West, S. Thomas, J. E. Herndon, et al. “Cardiopulmonary exercise testing prior to myeloablative allo-SCT: a feasibility study.” Bone Marrow Transplant 49, no. 10 (October 2014): 1330–36. https://doi.org/10.1038/bmt.2014.159.Full Text Link to Item
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Horwitz, Mitchell E., Nelson J. Chao, David A. Rizzieri, Gwynn D. Long, Keith M. Sullivan, Cristina Gasparetto, John P. Chute, et al. “Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment.” J Clin Invest 124, no. 7 (July 2014): 3121–28. https://doi.org/10.1172/JCI74556.Full Text Open Access Copy Link to Item
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Allen, Jessica L., Prasanthi V. Tata, Matthew S. Fore, Jenna Wooten, Sharmistha Rudra, Allison M. Deal, Andrew Sharf, et al. “Increased BCR responsiveness in B cells from patients with chronic GVHD.” Blood 123, no. 13 (March 27, 2014): 2108–15. https://doi.org/10.1182/blood-2013-10-533562.Full Text Link to Item
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Kanda, Junya, Gwynn D. Long, Cristina Gasparetto, Mitchell E. Horwitz, Keith M. Sullivan, John P. Chute, Ashley Morris, et al. “Reduced-intensity allogeneic transplantation using alemtuzumab from HLA-matched related, unrelated, or haploidentical related donors for patients with hematologic malignancies.” Biol Blood Marrow Transplant 20, no. 2 (February 2014): 257–63. https://doi.org/10.1016/j.bbmt.2013.11.010.Full Text Link to Item
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Sung, A. D., D. T. Grima, L. M. Bernard, S. Brown, G. Carrum, L. Holmberg, M. E. Horwitz, et al. “Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone.” Bone Marrow Transplantation 48, no. 11 (November 1, 2013): 1444–49. https://doi.org/10.1038/bmt.2013.80.Full Text
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Sung, A. D., D. T. Grima, L. M. Bernard, S. Brown, G. Carrum, L. Holmberg, M. E. Horwitz, et al. “Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone.” Bone Marrow Transplant 48, no. 11 (November 2013): 1444–49. https://doi.org/10.1038/bmt.2013.80.Full Text Open Access Copy Link to Item
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Kanda, J., L. Kaynar, Y. Kanda, V. K. Prasad, S. H. Parikh, L. Lan, T. Shen, et al. “Pre-engraftment syndrome after myeloablative dual umbilical cord blood transplantation: risk factors and response to treatment.” Bone Marrow Transplant 48, no. 7 (July 2013): 926–31. https://doi.org/10.1038/bmt.2012.279.Full Text Open Access Copy Link to Item
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Held, Lauren A., David Rizzieri, Gwynn D. Long, Jon P. Gockerman, Louis F. Diehl, Carlos M. de Castro, Joseph O. Moore, Mitchell E. Horwitz, Nelson J. Chao, and Cristina Gasparetto. “A Phase I study of arsenic trioxide (Trisenox), ascorbic acid, and bortezomib (Velcade) combination therapy in patients with relapsed/refractory multiple myeloma.” Cancer Invest 31, no. 3 (March 2013): 172–76. https://doi.org/10.3109/07357907.2012.756109.Full Text Link to Item
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Spasojevic, Ivan, Ligia R. S. da Costa, Mitchell E. Horwitz, Gwynn D. Long, Keith M. Sullivan, John P. Chute, Cristina Gasparetto, Ashley Morris, Nelson J. Chao, and David A. Rizzieri. “Mini test dose of intravenous busulfan (busulfex(®)) in allogeneic non-myeloablative stem cell transplantation, followed by liquid chromatography tandem-mass spectrometry.” Cancer Invest 30, no. 9 (November 2012): 679–82. https://doi.org/10.3109/07357907.2012.726386.Full Text Link to Item
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Kanda, Junya, Lun-Wei Chiou, Paul Szabolcs, Gregory D. Sempowski, David A. Rizzieri, Gwynn D. Long, Keith M. Sullivan, et al. “Immune recovery in adult patients after myeloablative dual umbilical cord blood, matched sibling, and matched unrelated donor hematopoietic cell transplantation.” Biol Blood Marrow Transplant 18, no. 11 (November 2012): 1664-1676.e1. https://doi.org/10.1016/j.bbmt.2012.06.005.Full Text Link to Item
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Horwitz, M. E., G. Long, P. Holman, E. Libby, G. C. Calandra, and J. R. Schriber. “Efficacy and safety of hematopoietic stem cell remobilization with plerixafor+G-CSF in adult patients with germ cell tumors.” Bone Marrow Transplant 47, no. 10 (October 2012): 1283–86. https://doi.org/10.1038/bmt.2012.21.Full Text Link to Item
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Eapen, Mary, Kwang Woo Ahn, Paul J. Orchard, Morton J. Cowan, Stella M. Davies, Anders Fasth, Anna Hassebroek, et al. “Long-term survival and late deaths after hematopoietic cell transplantation for primary immunodeficiency diseases and inborn errors of metabolism.” Biol Blood Marrow Transplant 18, no. 9 (September 2012): 1438–45. https://doi.org/10.1016/j.bbmt.2012.03.003.Full Text Open Access Copy Link to Item
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Horwitz, M. E., J. P. Chute, C. Gasparetto, G. D. Long, C. McDonald, A. Morris, D. A. Rizzieri, K. M. Sullivan, and N. J. Chao. “Preemptive dosing of plerixafor given to poor stem cell mobilizers on day 5 of G-CSF administration.” Bone Marrow Transplant 47, no. 8 (August 2012): 1051–55. https://doi.org/10.1038/bmt.2011.217.Full Text Link to Item
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Tolar, Jakub, H Joachim Deeg, Sally Arai, Mitchell Horwitz, Joseph H. Antin, John M. McCarty, Roberta H. Adams, et al. “Fludarabine-based conditioning for marrow transplantation from unrelated donors in severe aplastic anemia: early results of a cyclophosphamide dose deescalation study show life-threatening adverse events at predefined cyclophosphamide dose levels.” Biol Blood Marrow Transplant 18, no. 7 (July 2012): 1007–11. https://doi.org/10.1016/j.bbmt.2012.04.014.Full Text Link to Item
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Chen, D. -. F., V. K. Prasad, G. Broadwater, N. L. Reinsmoen, A. DeOliveira, A. Clark, K. M. Sullivan, et al. “Differential impact of inhibitory and activating Killer Ig-Like Receptors (KIR) on high-risk patients with myeloid and lymphoid malignancies undergoing reduced intensity transplantation from haploidentical related donors.” Bone Marrow Transplant 47, no. 6 (June 2012): 817–23. https://doi.org/10.1038/bmt.2011.181.Full Text Link to Item
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Kanda, J., M. E. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. P. Chute, A. Morris, et al. “Outcomes of a 1-day nonmyeloablative salvage regimen for patients with primary graft failure after allogeneic hematopoietic cell transplantation.” Bone Marrow Transplant 47, no. 5 (May 2012): 700–705. https://doi.org/10.1038/bmt.2011.158.Full Text Link to Item
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Kelsey, Chris R., Mitchell E. Horwitz, Junzo P. Chino, Oana Craciunescu, Beverly Steffey, Rodney J. Folz, Nelson J. Chao, David A. Rizzieri, and Lawrence B. Marks. “Severe pulmonary toxicity after myeloablative conditioning using total body irradiation: an assessment of risk factors.” Int J Radiat Oncol Biol Phys 81, no. 3 (November 1, 2011): 812–18. https://doi.org/10.1016/j.ijrobp.2010.06.058.Full Text Link to Item
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Kanda, Junya, David A. Rizzieri, Cristina Gasparetto, Gwynn D. Long, John P. Chute, Keith M. Sullivan, Ashley Morris, et al. “Adult dual umbilical cord blood transplantation using myeloablative total body irradiation (1350 cGy) and fludarabine conditioning.” Biol Blood Marrow Transplant 17, no. 6 (June 2011): 867–74. https://doi.org/10.1016/j.bbmt.2010.09.009.Full Text Link to Item
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Palmer, J., T. Goggins, G. Broadwater, N. Chao, M. Horwitz, A. Beaven, K. Sullivan, R. E. Coleman, and D. Rizzieri. “Early post transplant (F-18) 2-fluoro-2-deoxyglucose positron emission tomography does not predict outcome for patients undergoing auto-SCT in non-Hodgkin and Hodgkin lymphoma.” Bone Marrow Transplant 46, no. 6 (June 2011): 847–51. https://doi.org/10.1038/bmt.2010.203.Full Text Link to Item
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Wang, Endi, Charles Blake Hutchinson, Qin Huang, Chuanyi Mark Lu, Jennifer Crow, Frances F. Wang, Siby Sebastian, et al. “Donor cell-derived leukemias/myelodysplastic neoplasms in allogeneic hematopoietic stem cell transplant recipients: a clinicopathologic study of 10 cases and a comprehensive review of the literature.” Am J Clin Pathol 135, no. 4 (April 2011): 525–40. https://doi.org/10.1309/AJCPPJUQ9DNR1GHP.Full Text Link to Item
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Craciunescu, Oana I., Beverly A. Steffey, Chris R. Kelsey, Nicole A. Larrier, Cathy J. Paarz-Largay, Robert G. Prosnitz, Nelson Chao, et al. “Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial.” Int J Radiat Oncol Biol Phys 79, no. 4 (March 15, 2011): 1248–55. https://doi.org/10.1016/j.ijrobp.2010.05.036.Full Text Link to Item
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Horwitz, Mitchell E. “Reduced intensity versus myeloablative allogeneic stem cell transplantation for the treatment of acute myeloid leukemia, myelodysplastic syndrome and acute lymphoid leukemia.” Curr Opin Oncol 23, no. 2 (March 2011): 197–202. https://doi.org/10.1097/CCO.0b013e328342b82a.Full Text Link to Item
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Turbeville, Sean, Helen Nicely, J Douglas Rizzo, Tanya L. Pedersen, Paul J. Orchard, Mitchell E. Horwitz, Edwin M. Horwitz, Paul Veys, Carmem Bonfim, and Amal Al-Seraihy. “Clinical outcomes following hematopoietic stem cell transplantation for the treatment of mucopolysaccharidosis VI.” Mol Genet Metab 102, no. 2 (February 2011): 111–15. https://doi.org/10.1016/j.ymgme.2010.09.010.Full Text Link to Item
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Rizzieri, David A., Christopher Crout, Robert Storms, Jared Golob, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan, et al. “Feasibility of low-dose interleukin-2 therapy following T-cell-depleted nonmyeloablative allogeneic hematopoietic stem cell transplantation from HLA-matched or -mismatched family member donors.” Cancer Invest 29, no. 1 (January 2011): 56–61. https://doi.org/10.3109/07357907.2010.535055.Full Text Link to Item
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Horwitz, M. E., and N. Chao. “Umbilical cord blood transplantation for treatment of non-malignant disorders.” Cellular Therapy and Transplantation 2, no. 7 (December 1, 2010). https://doi.org/10.3205/ctt-2010-en-000069.01.Full Text
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Rizzieri, David A., Robert Storms, Dong-Feng Chen, Gwynn Long, Yiping Yang, Daniel A. Nikcevich, Cristina Gasparetto, et al. “Natural killer cell-enriched donor lymphocyte infusions from A 3-6/6 HLA matched family member following nonmyeloablative allogeneic stem cell transplantation.” Biol Blood Marrow Transplant 16, no. 8 (August 2010): 1107–14. https://doi.org/10.1016/j.bbmt.2010.02.018.Full Text Link to Item
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Crout, Christopher A., Liang-Piu Koh, Jon P. Gockerman, Joseph O. Moore, Carlos Decastro, Gwynn D. Long, Louis Diehl, et al. “Overcoming drug resistance in mantle cell lymphoma using a combination of dose-dense and intense therapy.” Cancer Invest 28, no. 6 (July 2010): 654–60. https://doi.org/10.3109/07357901003631015.Full Text Link to Item
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Horwitz, Mitchell E., and Nelson Chao. “Non-myeloablative umbilical cord blood transplantation.” Best Pract Res Clin Haematol 23, no. 2 (June 2010): 231–36. https://doi.org/10.1016/j.beha.2010.06.001.Full Text Link to Item
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Gasparetto, Cristina, Jon P. Gockerman, Louis F. Diehl, Carlos M. de Castro, Joseph O. Moore, Gwynn D. Long, Mitchell E. Horwitz, et al. “"Short course" bortezomib plus melphalan and prednisone as induction prior to transplant or as frontline therapy for nontransplant candidates in patients with previously untreated multiple myeloma.” Biol Blood Marrow Transplant 16, no. 1 (January 2010): 70–77. https://doi.org/10.1016/j.bbmt.2009.08.017.Full Text Link to Item
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DiPersio, John F., Edward A. Stadtmauer, Auayporn Nademanee, Ivana N. M. Micallef, Patrick J. Stiff, Jonathan L. Kaufman, Richard T. Maziarz, et al. “Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma.” Blood 113, no. 23 (June 4, 2009): 5720–26. https://doi.org/10.1182/blood-2008-08-174946.Full Text Link to Item
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Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P134 A phase II pilot study of sorafenib in patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70215-2.Full Text
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Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P129 A pilot study of decitabine in combination with arsenic trioxide for patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70210-3.Full Text
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Qasim, Waseem, Marina Cavazzana-Calvo, E Graham Davies, Jeffery Davis, Michel Duval, Gretchen Eames, Nuno Farinha, et al. “Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency.” Pediatrics 123, no. 3 (March 2009): 836–40. https://doi.org/10.1542/peds.2008-1191.Full Text Link to Item
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Rizzieri, D. A., P. Dev, G. D. Long, C. Gasparetto, K. M. Sullivan, Ml Horwitz, J. Chute, and N. J. Chao. “Response and toxicity of donor lymphocyte infusions following T-cell depleted non-myeloablative allogeneic hematopoietic SCT from 3-6/6 HLA matched donors.” Bone Marrow Transplant 43, no. 4 (February 2009): 327–33. https://doi.org/10.1038/bmt.2008.321.Full Text Link to Item
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Horwitz, M. E., G. Tunes da Silva, M. Eapen, and E. M. Horwitz. “Survival Following Allogeneic Stem Cell Transplantation for Congenital Immunodeficiency and Metabolic Disorders.” Biology of Blood and Marrow Transplantation 15, no. 2 (February 2009): 78–78. https://doi.org/10.1016/j.bbmt.2008.12.240.Full Text
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Horwitz, Mitchell E., Ashley Morris, Cristina Gasparetto, Keith Sullivan, Gwynn Long, John Chute, David Rizzieri, Jackie McPherson, and Nelson Chao. “Myeloablative intravenous busulfan/fludarabine conditioning does not facilitate reliable engraftment of dual umbilical cord blood grafts in adult recipients.” Biol Blood Marrow Transplant 14, no. 5 (May 2008): 591–94. https://doi.org/10.1016/j.bbmt.2008.02.016.Full Text Link to Item
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Byrne, B. J., M. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. Chute, N. J. Chao, and D. A. Rizzieri. “Outcomes of a second non-myeloablative allogeneic stem cell transplantation following graft rejection.” Bone Marrow Transplant 41, no. 1 (January 2008): 39–43. https://doi.org/10.1038/sj.bmt.1705882.Full Text Link to Item
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Uzel, Gulbu, Emilia Tng, Sergio D. Rosenzweig, Amy P. Hsu, Jacqueline M. Shaw, Mitchell E. Horwitz, Gilda F. Linton, et al. “Reversion mutations in patients with leukocyte adhesion deficiency type-1 (LAD-1).” Blood 111, no. 1 (January 1, 2008): 209–18. https://doi.org/10.1182/blood-2007-04-082552.Full Text Link to Item
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Horwitz, Mitchell E., Ivan Spasojevic, Ashley Morris, Marilyn Telen, James Essell, Cristina Gasparetto, Keith Sullivan, et al. “Fludarabine-based nonmyeloablative stem cell transplantation for sickle cell disease with and without renal failure: clinical outcome and pharmacokinetics.” Biol Blood Marrow Transplant 13, no. 12 (December 2007): 1422–26. https://doi.org/10.1016/j.bbmt.2007.08.050.Full Text Link to Item
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Horwitz, Mitchell E. “Sources of human and murine hematopoietic stem cells.” Curr Protoc Immunol Chapter 22 (November 2007): 22A.2.1-22A.2.6. https://doi.org/10.1002/0471142735.im22a02s79.Full Text Link to Item
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Hanson, Kimberly E., L Barth Reller, Joanne Kurtzberg, Mitchell Horwitz, Gwynn Long, and Barbara D. Alexander. “Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens from allogeneic-stem-cell transplant recipients.” J Clin Microbiol 45, no. 6 (June 2007): 1972–73. https://doi.org/10.1128/JCM.02515-06.Full Text Link to Item
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Rizzieri, David A., Liang Piu Koh, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan, Mitchell Horwitz, John Chute, et al. “Partially matched, nonmyeloablative allogeneic transplantation: clinical outcomes and immune reconstitution.” J Clin Oncol 25, no. 6 (February 20, 2007): 690–97. https://doi.org/10.1200/JCO.2006.07.0953.Full Text Link to Item
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Brenner, Sebastian, Martin F. Ryser, Uimook Choi, Narda Whiting-Theobald, Eberhard Kuhlisch, Gilda Linton, Elizabeth Kang, et al. “Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells.” Mol Ther 14, no. 2 (August 2006): 202–11. https://doi.org/10.1016/j.ymthe.2006.01.015.Full Text Link to Item
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Bleesing, Jack J., Margarida M. Souto-Carneiro, William J. Savage, Margaret R. Brown, Cynthia Martinez, Sule Yavuz, Sebastian Brenner, et al. “Patients with chronic granulomatous disease have a reduced peripheral blood memory B cell compartment.” J Immunol 176, no. 11 (June 1, 2006): 7096–7103. https://doi.org/10.4049/jimmunol.176.11.7096.Full Text Link to Item
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Horwitz, Mitchell E., and Keith M. Sullivan. “Chronic graft-versus-host disease.” Blood Rev 20, no. 1 (January 2006): 15–27. https://doi.org/10.1016/j.blre.2005.01.007.Full Text Link to Item
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Yamashita, Kouhei, Mitchell E. Horwitz, Akua Kwatemaa, Effie Nomicos, Kathleen Castro, Robert Sokolic, Susan F. Foster, et al. “Unique abnormalities of CD4(+) and CD8(+) central memory cells associated with chronic graft-versus-host disease improve after extracorporeal photopheresis.” Biol Blood Marrow Transplant 12, no. 1 Suppl 2 (January 2006): 22–30. https://doi.org/10.1016/j.bbmt.2005.11.004.Full Text Link to Item
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Roesler, Joachim, Mitchell E. Horwitz, Capucine Picard, Pierre Bordigoni, Graham Davies, Ewa Koscielniak, Mike Levin, et al. “Hematopoietic stem cell transplantation for complete IFN-gamma receptor 1 deficiency: a multi-institutional survey.” J Pediatr 145, no. 6 (December 2004): 806–12. https://doi.org/10.1016/j.jpeds.2004.08.021.Full Text Link to Item
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Chao, Nelson. “Hematopoietic stem cell transplantation.” Curr Opin Hematol 11, no. 6 (November 2004): 373–74. https://doi.org/10.1097/01.moh.0000144500.82861.c0.Full Text Link to Item
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Chao, Nelson J., Liang-Piu Koh, Gwynn D. Long, Cristina Gasparetto, Mitchell Horwitz, Ashley Morris, Martha Lassiter, Keith M. Sullivan, and David A. Rizzieri. “Adult recipients of umbilical cord blood transplants after nonmyeloablative preparative regimens.” Biol Blood Marrow Transplant 10, no. 8 (August 2004): 569–75. https://doi.org/10.1016/j.bbmt.2004.05.001.Full Text Link to Item
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Yamashita, Kouhei, Uimook Choi, Patricia C. Woltz, Susan F. Foster, Michael C. Sneller, Francis T. Hakim, Daniel H. Fowler, et al. “Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells.” Blood 103, no. 10 (May 15, 2004): 3986–88. https://doi.org/10.1182/blood-2003-09-3286.Full Text Link to Item
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Bolan, Charles D., Yu Ying Yau, Herbert C. Cullis, Mitchell E. Horwitz, Crystal L. Mackall, A John Barrett, Harry L. Malech, Nadja N. Rehak, Alan S. Wayne, and Susan F. Leitman. “Pediatric large-volume leukapheresis: a single institution experience with heparin versus citrate-based anticoagulant regimens.” Transfusion 44, no. 2 (February 2004): 229–38. https://doi.org/10.1111/j.1537-2995.2004.00668.x.Full Text Link to Item
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Brenner, Sebastian, Narda L. Whiting-Theobald, Gilda F. Linton, Kevin L. Holmes, Mindy Anderson-Cohen, Patrick F. Kelly, Elio F. Vanin, et al. “Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.” Blood 102, no. 8 (October 15, 2003): 2789–97. https://doi.org/10.1182/blood-2002-05-1482.Full Text Link to Item
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Horwitz, Mitchell E., Gulbu Uzel, Gilda F. Linton, Judi A. Miller, Margaret R. Brown, Harry L. Malech, and Steven M. Holland. “Persistent Mycobacterium avium infection following nonmyeloablative allogeneic peripheral blood stem cell transplantation for interferon-gamma receptor-1 deficiency.” Blood 102, no. 7 (October 1, 2003): 2692–94. https://doi.org/10.1182/blood-2003-04-1268.Full Text Link to Item
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Abo-Zena, Reem A., and Mitchell E. Horwitz. “Immunomodulation in stem-cell transplantation.” Curr Opin Pharmacol 2, no. 4 (August 2002): 452–57. https://doi.org/10.1016/s1471-4892(02)00174-1.Full Text Link to Item
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Barron, K. S., C. Wallace, C. Woolfrey CEA, R. M. Laxer, R. Hirsch, M. Horwitz, J. Siegel, et al. “Autologous stem cell transplantation for pediatric rheumatic diseases.” J Rheumatol 28, no. 10 (October 2001): 2337–58.Link to Item
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Savage, W. J., J. J. Bleesing, D. Douek, M. R. Brown, G. M. Linton, H. L. Malech, and M. E. Horwitz. “Lymphocyte reconstitution following non-myeloablative hematopoietic stem cell transplantation follows two patterns depending on age and donor/recipient chimerism.” Bone Marrow Transplant 28, no. 5 (September 2001): 463–71. https://doi.org/10.1038/sj.bmt.1703176.Full Text Link to Item
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Horwitz, M. E., A. J. Barrett, M. R. Brown, C. S. Carter, R. Childs, J. I. Gallin, S. M. Holland, et al. “Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft.” N Engl J Med 344, no. 12 (March 22, 2001): 881–88. https://doi.org/10.1056/NEJM200103223441203.Full Text Link to Item
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Horwitz, M. E. “Stem-cell transplantation for inherited immunodeficiency disorders.” Pediatr Clin North Am 47, no. 6 (December 2000): 1371–87. https://doi.org/10.1016/s0031-3955(05)70276-5.Full Text Link to Item
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Centola, M., G. Wood, D. M. Frucht, J. Galon, M. Aringer, C. Farrell, D. W. Kingma, et al. “The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators.” Blood 95, no. 10 (May 15, 2000): 3223–31.Link to Item
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Horwitz, M. E., H. L. Malech, S. M. Anderson, L. J. Girard, D. M. Bodine, and D. Orlic. “Granulocyte colony-stimulating factor mobilized peripheral blood stem cells enter into G1 of the cell cycle and express higher levels of amphotropic retrovirus receptor mRNA.” Exp Hematol 27, no. 7 (July 1999): 1160–67. https://doi.org/10.1016/s0301-472x(99)00049-1.Full Text Link to Item
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Conference Papers
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Lin, Chenyu, Aurelie Schwarzbach, Jaime Sanz, Pau Montesinos, Patrick Stiff, Suhag Parikh, Claudio Brunstein, et al. “Multicenter Long-Term Follow-Up of Allogeneic Hematopoietic Cell Transplantation with Omidubicel: A Pooled Analysis of Five Prospective Clinical Trials.” In Transplant Cell Ther, 29:338.e1-338.e6, 2023. https://doi.org/10.1016/j.jtct.2023.01.031.Full Text Link to Item
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Lin, Chenyu, Gautam Sajeev, Patrick Stiff, Claudio Brunstein, Corey Cutler, Guillermo Sanz, Caroline Lindemans, et al. “Health-Related Quality of Life Following Allogeneic Hematopoietic Stem Cell Transplantation with Omidubicel Versus Standard Umbilical Cord Blood,” 2022.
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Smith, Patrick J., Meagan Lew, Yen Lowder, Kristi Romero, Jillian C. Thompson, Lauren Bohannon, Alyssa Pittman, et al. “Cognitive impairment in candidates for allogeneic hematopoietic stem cell transplantation.” In Bone Marrow Transplant, 57:89–94, 2022. https://doi.org/10.1038/s41409-021-01470-z.Full Text Link to Item
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Lin, Chenyu, Laura Morrison, Edwin Alyea, Taewoong Choi, Cristina Gasparetto, Gwynn Long, Richard Lopez, et al. “Allogeneic Stem Cell Transplantation with Omidubicel: Long-Term Follow-Up from a Single Center.” In Blood, 138:1827–1827. American Society of Hematology, 2021.Link to Item
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Brunstein, Claudio G., Paul V. O’Donnell, Brent R. Logan, Luciano J. Costa, Corey Cutler, Michael Craig, William J. Hogan, et al. “Impact of Center Experience with Donor Type and Treatment Platform on Outcomes: A Secondary Analysis BMT CTN 1101.” In Blood, 138:3956–3956. American Society of Hematology, 2021. https://doi.org/10.1182/blood-2021-145527.Full Text
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Szabolcs, Paul, Stuart Levy, Dima Yackoubov, Aviad Pato, Einat Galamidi-Cohen, and Mitchell E. Horwitz. “Hematopoietic Stem Cell Transplantation (HSCT) with Omidubicel Is Associated with Robust Immune Reconstitution and Lower Rates of Severe Infection Compared to Standard Umbilical Cord Blood Transplantation.” In Blood, 138:333–333. American Society of Hematology, 2021. https://doi.org/10.1182/blood-2021-153408.Full Text
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Pabon, Cindy M., Zhiguo Li, Therese Hennig, Carlos De Castro, Jadee Neff, Mitchell E. Horwitz, Thomas W. Leblanc, et al. “Morphologic Leukemia-Free State in Acute Myeloid Leukemia Is Sufficient for Successful Allogeneic Hematopoietic Stem Cell Transplant.” In Blood, 136:24–25. American Society of Hematology, 2020. https://doi.org/10.1182/blood-2020-133901.Full Text
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Maung, Ko, Nelson Jen An Chao, Kelly Corbet, Ashley Morris Engemann, Cristina Gasparetto, Mitchell Horwitz, Yubin Kang, et al. “CLO20-049: Retrospective Study of Safety and Toxicity Profile Comparison for Propylene Glycol-Free Melphalan (Evomela®) and Generic Melphalan.” In Journal of the National Comprehensive Cancer Network, 18:CLO20-049. Harborside Press, LLC, 2020. https://doi.org/10.6004/jnccn.2019.7412.Full Text
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Ramalingam, Sendhilnathan, Sharareh Siamakpour-Reihani, Lauren Bohannon, Yi Ren, Alexander Sibley, Andrew Nixon, Jing Lyu, et al. “Phase II Trial of Pasireotide to Prevent GI Toxicity and Acute Gvhd in Allogeneic HSCT.” In Biology of Blood and Marrow Transplantation, 26:S48–49. ELSEVIER SCIENCE INC, 2020.Link to Item
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Brunstein, Claudio, Paul V. O’Donnell, Mary Eapen, Brent Logan, Joseph H. Antin, Peter Dawson, Steven Devine, et al. “Results of Bmt Ctn Protocol 1101 a Multicenter Phase Iii Randomized Trial of Transplantation of Double Umbilical Cord Blood vs. Hla-haploidentical-related Bone Marrow.” In Bone Marrow Transplantation, 55:16–17, 2020.Link to Item
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Bohannon, Lauren M., Kristin M. Page, Yi Ren, Sin-Ho Jung, Vinay K. Giri, Meagan V. Lew, Matthew Kelly, et al. “Decreased Mortality after the First Year of Allogeneic Hematopoietic Stem Cell Transplant in Recipients of Umbilical Cord Blood Vs. Matched Related or Matched Unrelated Donors.” In Blood, 134:4613–4613. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-126906.Full Text
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Giri, Vinay K., Kristin G. Kegerreis, Yi Ren, Lauren M. Bohannon, Erica Lobaugh-Jin, Julia A. Messina, Anita Matthews, et al. “Daily Chlorhexidine Gluconate Bathing Reduces the Rate of Bloodstream Infections in Adults Undergoing Inpatient Hematopoietic Stem Cell Transplantation.” In Blood, 134:2210–2210. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-122272.Full Text
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Lew, Meagan V., Yi Ren, Yen P. Lowder, Kristi M. Romero, Jillian C. Thompson, Lauren M. Bohannon, Harvey Cohen, et al. “Geriatric Assessment Identifies Impairments in Younger Candidates for Allogeneic Hematopoietic Stem Cell Transplantation.” In Blood, 134:1984–1984. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-127264.Full Text
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Maung, Ko Ko Ko, Mohammad Chaudhry, Yi Ren, Sin-Ho Jung, Kristi M. Romero, Kelly Corbet, Nelson J. Chao, et al. “Pre-Transplant Hepatic Steatosis (fatty liver) Predicts Chronic Graft-Vs-Host Disease but Does Not Affect Mortality.” In Blood, 134:5731–5731. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-121830.Full Text
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McManigle, William C., Rachel A. DiCioccio, Sarah Anand, Zhiguo Li, Jonathan C. Poe, Krista R. Nichols, Amy N. Suthers, et al. “Evaluation of the Oral SYK Inhibitor Fostamatinib in Patients after Allogeneic Transplantation for Chronic Graft-Versus-Host Disease.” In Blood, 134:4521–4521. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-130742.Full Text
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Poe, Jonathan C., Dadong Zhang, Jichun Xie, Rachel A. DiCioccio, Xiaodi Qin, Jiyuan Fang, Vincent T. Ho, et al. “Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd.” In Blood, 134:874–874. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-130928.Full Text
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Koning, Coco de, Mitchell E. Horwitz, Guillermo Sanz, Madan Jagasia, John E. Wagner, Patrick J. Stiff, Rabi Hanna, Daniela Cilloni, Stefan Nierkens, and Jaap-Jan Boelens. “Rapid and Robust CD4+and CD8+T-, NK-, B-Cell, Dendritic Cell, and Monocyte Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation.” In Biology of Blood and Marrow Transplantation, Vol. 25, 2019.Link to Item
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Lowder, Yen P., Meredith Moyers, Jenna Seckar, Elisabeth Gorecki, Kelli Oldham, Jennifer Frutchey, Kara Beasley, et al. “Nutrition Practices in Hematopoietic Stem Cell Transplantation (HSCT): A Comparison between Guidelines and Clinical Practice.” In Biology of Blood and Marrow Transplantation, Vol. 25, 2019.Link to Item
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Maung, Ko Ko, Benny J. Chen, David A. Rizzieri, Cristina Gasparetto, Keith Sullivan, Gwynn D. Long, Ashley Morris Engemann, et al. “Phase I, Dose Escalation Study of Naive T-Cell Depleted Donor Lymphocyte Infusion Following Allogeneic Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, Vol. 25, 2019.Link to Item
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Boelens, Jaap Jan, Coco de Koning, Mitchell E. Horwitz, Guillermo Sanz, Madan Jagasia, John E. Wagner, Patrick J. Stiff, Rabi Hanna, Daniela Cilloni, and Stefan Nierkens. “Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation.” In Blood, 132:2123–2123. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-116700.Full Text
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Foster, Yevgeniya, Michael J. Grant, Samantha M. Thomas, Blake Cameron, Doug Raiff, Kelly Corbet, Christopher Ferreri, and Mitchell E. Horwitz. “Treatment with Foscarnet after Allogeneic Hematopoietic-Cell Transplant (AlloHCT) Is Associated with Long-Term Loss of Renal Function.” In Blood, 132:4594–4594. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-113189.Full Text
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Leventhal, Joseph R., John P. Galvin, James Mathew, Lorenzo Gallon, Kadiyala Ravindra, Mitchell E. Horwitz, Michael Abecassis, and Suzanne T. Ildstad. “Use of a Processed Hematopoietic Stem Cell Product (FCRx) in Unmatched Related and Unrelated Donor — Recipient Pairs Is Associated with High Levels of Donor Chimerism and Donor-Specific Tolerance to Kidney Allografts.” In Blood, 132:202–202. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-118832.Full Text
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Parikh, Suhag, Joel A. Brochstein, Stephen Wease, Paul L. Martin, Mitchell E. Horwitz, Aurelie Schwarzbach, and Joanne Kurtzberg. “A Novel Therapy for Sickle Cell Disease (SCD): Co-Transplantation of Nicord (R) [Ex Vivo Expanded Umbilical Cord Blood (UCB) Progenitor Cells with Nicotinamide] and an Unmanipulated Unrelated UCB Graft Leads to Successful Engraftment and Cure of Severe SCD.” In Biology of Blood and Marrow Transplantation, 24:S157–58. ELSEVIER SCIENCE INC, 2018.Link to Item
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Horwitz, Mitchell E., Daniela Cilloni, David Valcarcel, Francesco Frassoni, Jaap-Jan Boelens, Madan Jagasia, John E. Wagner, et al. “Nicord Single Unit Expanded Umbilical Cord Blood Transplantation (UCBT): Final Results of a Multicenter Phase I/ II Trial.” In Biology of Blood and Marrow Transplantation, 24:S57–S57. Elsevier BV, 2018. https://doi.org/10.1016/j.bbmt.2017.12.628.Full Text
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Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Gwynn D. Long, Richard Lopez, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Thiotepa, Total Body Irradiation, and Fludarabine Conditioning.” In Biol Blood Marrow Transplant, 23:1949–54, 2017. https://doi.org/10.1016/j.bbmt.2017.06.027.Full Text Link to Item
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Parikh, Suhag, Joel Brochstein, Paul L. Martin, Mitchell E. Horwitz, Einat Galamidi, Iddo Peleg, Uri Goshen, et al. “Successful Engraftment of Umbilical Cord Blood (UCB) Cells after Co-Transplantation of Nicord (R) (Ex Vivo Expanded UCB Progenitor Cells with Nicotinamide) and an Unmanipulated UCB Unit after Myeloablative Chemotherapy in Severe Sickle Cell Disease.” In Biology of Blood and Marrow Transplantation, 23:S150–51, 2017.Link to Item
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Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Richard Lopez, Gwynn D. Long, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Total Body Irradiation, Fludarabine, and Thiotepa Conditioning.” In Blood, 128:3395–3395. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.3395.3395.Full Text
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Parikh, Suhag H., Joel Brochstein, Paul L. Martin, Mitchell E. Horwitz, Einat Galamidi, Iddo Peleg, Uri Goshen, et al. “Successful Engraftment of Donor Umbilical Cord Blood (UCB) Cells after Co-Transplantation of Nicord® (Ex Vivo Expanded UCB Progenitor Cells with Nicotinamide) and a Second Unmanipulated Cord Blood Unit after Myeloablative Chemotherapy in Pediatric Patients with Severe Sickle Cell Disease.” In Blood, 128:3651–3651. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.3651.3651.Full Text
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Soiffer, Robert J., Haesook T. Kim, Joseph McGuirk, Mitchell E. Horwitz, Laura Johnston, Mrinal M. Patnaik, Witold Rybka, et al. “A Prospective Randomized Double Blind Phase 3 Clinical Trial of Anti- T Lymphocyte Globulin (ATLG) to Assess Impact on Chronic Graft-Versus-Host Disease (cGVHD) Free Survival in Patients Undergoing HLA Matched Unrelated Myeloablative Hematopoietic Cell Transplantation (HCT).” In Blood, 128:505–505. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.505.505.Full Text
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Huang, Li-Wen, Wendi Bacon, Constance Cirrincione, Bercedis Peterson, Gwynn D. Long, David A. Rizzieri, Mitchell E. Horwitz, et al. “Efficacy of Autologous Stem Cell Transplantation in Older Multiple Myeloma Patients.” In Biology of Blood and Marrow Transplantation, 22:S223–S223. Elsevier BV, 2016. https://doi.org/10.1016/j.bbmt.2015.11.626.Full Text
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Stephens, Sarah J., Samantha Thomas, David A. Rizzieri, Mitchell E. Horwitz, Nelson J. Chao, Ashley M. Engemann, Martha Lassiter, and Chris R. Kelsey. “Myeloablative conditioning with total body irradiation for AML: Balancing survival and pulmonary toxicity.” In Adv Radiat Oncol, 1:272–80, 2016. https://doi.org/10.1016/j.adro.2016.07.001.Full Text Open Access Copy Link to Item
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Chen, Yi-Bin, Jennifer Le-Rademacher, Deidre Marie Kiefer, Mehdi Hamadani, John F. DiPersio, Mark R. Litzow, Michael Craig, et al. “A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells in Recipients with Hematological Malignancies.” In Blood, Vol. 126. AMER SOC HEMATOLOGY, 2015.Link to Item
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Scott, Bart L., Marcelo C. Pasquini, Brent Logan, Juan Wu, Steve Devine, David L. Porter, Richard T. Maziarz, et al. “Results of a Phase III Randomized, Multi-Center Study of Allogeneic Stem Cell Transplantation after High Versus Reduced Intensity Conditioning in Patients with Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML): Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0901.” In Blood, Vol. 126. American Society of Hematology, 2015. https://doi.org/10.1182/blood.v126.23.lba-8.lba-8.Full Text
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Green, Michael M. B., Mitchell E. Horwitz, Yubin Kang, Nelson J. Chao, Gwynn D. Long, David Rizzieri, Cristina Gasparetto, et al. “Administration of Plerixafor (a CXCR4 antagonist) Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation Enhances Platelet Recovery in a Phase I/II Trial.” In Biology of Blood and Marrow Transplantation, 21:S31–32. Elsevier BV, 2015. https://doi.org/10.1016/j.bbmt.2014.11.024.Full Text
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Pasquini, Marcelo C., Jennifer Le Rademacher, Christopher Flowers, Michael Lill, Luciano J. Costa, Tsiporah B. Shore, William Vaughan, et al. “Matched Pair Comparison of Busulfan/Cyclophosphamide/Etoposide (BuCyE) to Carmustine/Etoposide/Cytarabine/Melphalan (BEAM) Conditioning Regimen Prior to Autologous Hematopoietic Cell Transplantation (autoHCT) for Lymphoma.” In Biology of Blood and Marrow Transplantation, 20:S162–S162. Elsevier BV, 2014. https://doi.org/10.1016/j.bbmt.2013.12.259.Full Text
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Horwitz, Mitchell E., Patrick J. Stiff, Nelson J. Chao, David Rizzieri, Gwynn Long, Keith Sullivan, Cristina Gasparetto, et al. “Nicord® Expanded Hematopoietic Progenitor Cells (HPC) Are Capable of Outcompeting the Unmanipulated (UM) Cord Blood Unit and of Prolonged Myeloid and Lymphoid Engraftment Following Myeloablative Dual Umbilical Cord Blood (UCB) Transplantation.” In Biology of Blood and Marrow Transplantation, 19:S118–S118. Elsevier BV, 2013. https://doi.org/10.1016/j.bbmt.2012.11.044.Full Text
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Sung, Anthony D., Julia A. M. Sung, Kelly Corbet, Vera Hars, Lan Lan, Gloria Broadwater, Ashley Zanter, et al. “Surgical Mask Usage Reduces the Incidence of Parainfleunza Virus 3 in Recipients of Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, 19:S271–72. Elsevier BV, 2013. https://doi.org/10.1016/j.bbmt.2012.11.375.Full Text
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Sung, Anthony D., Julia A. M. Sung, Kelly Corbet, Gloria Broadwater, Vera Hars, Ashley Zanter, Nelson J. Chao, and Mitchell E. Horwitz. “Surgical Mask Usage Reduces the Incidence of Parainfluenza Virus 3 in Recipients of Stem Cell Transplantation.” In Blood, Vol. 120. AMER SOC HEMATOLOGY, 2012.Link to Item
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Sung, Anthony D., Julia A. M. Sung, Kelly Corbet, Gloria Broadwater, Vera Hars, Ashley Zanter, Nelson J. Chao, and Mitchell E. Horwitz. “Surgical Mask Usage Reduces the Incidence of Parainfluenza Virus 3 in Recipients of Stem Cell Transplantation.” In Blood, 120:462–462. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.462.462.Full Text
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Kanda, J., L. Kaynar, Y. Kanda, V. K. Prasad, S. H. Parikh, D. A. Rizzieri, G. D. Long, et al. “Use of Cyclosporine Is Associated with the Increase in Pre-Engraftment Syndrome After Myeloablative Dual Cord Blood Transplantation.” In Biology of Blood and Marrow Transplantation, 18:S332–S332. Elsevier BV, 2012. https://doi.org/10.1016/j.bbmt.2011.12.336.Full Text
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Lill, M., S. Lim, R. F. Yeh, E. Waller, L. J. Costa, T. Shore, M. Craig, et al. “Dose Precision Using a Pretransplant Test PK of Intravenous Busulfan Prior to BuCyVP-16 Preparative Regimen in Lymphoma.” In Biology of Blood and Marrow Transplantation, 18:S246–S246. Elsevier BV, 2012. https://doi.org/10.1016/j.bbmt.2011.12.126.Full Text
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Bacon, Wendi A., Gwynn D. Long, David A. Rizzieri, Mitchell E. Horwitz, John P. Chute, Keith M. Sullivan, Amanda Yopp, Angela Johns, Nelson J. Chao, and Cristina Gasparetto. “Impact of High Dose Cyclophosphamide on the Outcome of Autologous Stem Cell Transplant in Patients with Newly Diagnosed Multiple Myeloma.” In Blood, 118:1765–1765. AMER SOC HEMATOLOGY, 2011.Link to Item
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Chao, Nelson J., Daniel T. Grima, George Carrum, Leona Holmberg, Henry C. Fung, Stephen Brown, Mitchell E. Horwitz, et al. “Chemo-Mobilization Provides Superior Mobilization and Collection in Autologous Stem Cell Transplants but with Less Predictability and At a Higher Cost.” In Blood, 118:1729–1729. AMER SOC HEMATOLOGY, 2011.Link to Item
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Chao, Nelson J., Lisa M. Bernard, George Carrum, Henry C. Fung, Daniel T. Grima, Leona Holmberg, Stephen Brown, et al. “Differences in Stem Cell Collection Practices and Related Outcomes Between Centers That Conduct and Do Not Conduct Aphaeresis on Weekends.” In Blood, 118:839–40. AMER SOC HEMATOLOGY, 2011.Link to Item
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Gasparetto, Cristina, Wendi A. Bacon, Phuong Doan, David A. Rizzieri, Mitchell E. Horwitz, John P. Chute, Keith M. Sullivan, et al. “High Dose BCNU/Melphalan Preparative Regimen Doubles Event Free Survival of Myeloma Patients Undergoing Autologous Transplantation.” In Blood, 118:879–879. AMER SOC HEMATOLOGY, 2011.Link to Item
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Kanda, Junya, David A. Rizzieri, Gwynn D. Long, Cristina Gasparetto, John P. Chute, Keith M. Sullivan, Ashley Morris, et al. “The Impact of Lymphocyte Subset Recovery At 3 Months on Progression-Free Survival After Myeloablative Allogeneic Stem Cell Transplantation.” In Blood, 118:1736–1736. AMER SOC HEMATOLOGY, 2011.Link to Item
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Kanda, J., M. E. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. P. Chute, A. Morris, T. Hennig, N. J. Chao, and D. A. Rizzieri. “Outcomes of a 1-Day Nonmyeloablative Preparative Regimen for Primary Graft Failure After Allogeneic Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, 17:S308–S308. Elsevier BV, 2011. https://doi.org/10.1016/j.bbmt.2010.12.460.Full Text
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Biernacki, Melinda A., Maureen Okam, Shalini Shenoy, Lakshmanan Krishnamurti, Mitchell E. Horwitz, Donna Neuberg, Joseph H. Antin, and Catherine J. Wu. “Long-Term Follow-up of Adults with Severe Sickle Cell Disease After Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning.” In Blood, 116:120–120. AMER SOC HEMATOLOGY, 2010.Link to Item
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Chiou, Lun-Wei, Junya Kanda, Paul Szabolcs, Gregory E. Sempowski, Jeffrey Hale, Donna Niedzwiecki, Gloria Broadwater, Nelson J. Chao, and Mitchell E. Horwitz. “A Comprehensive Comparison Immune Recovery In Adult Patients Following Allogeneic Umbilical Cord Blood, Matched Sibling and Matched Unrelated Donor Stem Cell Transplantation.” In Blood, 116:954–55. AMER SOC HEMATOLOGY, 2010.Link to Item
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Horwitz, Mitchell E., Edward Gorak, Peter Holman, Edward Libby, Dirk Huebner, Purvi D. Mody, and Jeffrey R. Schriber. “Efficacy and Safety of Hematopoietic Stem Cell Remobilization with Plerixafor (Mozobil (R)) plus G-CSF In Adult Patients with Non-Hematologic Malignancies.” In Blood, 116:925–925. AMER SOC HEMATOLOGY, 2010.Link to Item
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Hutchinson, Charles Blake, Jennifer H. Crow, Huang Qin, Chuanyi M. Lu, Siby Sebastain, Catherine Rehder, Anand S. Lagoo, et al. “Donor Cell Leukemia: A Clinicopathological Study of 9 Cases and a Comprehensive Review of Literature.” In Blood, 116:1423–24. AMER SOC HEMATOLOGY, 2010.Link to Item
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Kanda, Junya, Gwynn D. Long, Cristina Gasparetto, Mitchell E. Horwitz, Keith M. Sullivan, John P. Chute, Ashley Morris, Zhiguo Li, Nelson J. Chao, and David A. Rizzieri. “Prospective, Biological Randomized Study of T-Cell Depleted Nonmyeloablative Allogeneic Transplantation From HLA-Matched Related, Unrelated or Haploidentical Donors for Patients with Hematologic Malignancies.” In Blood, 116:1456–57. AMER SOC HEMATOLOGY, 2010.Link to Item
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Khan, T., K. Richard, G. Broadwater, S. E. Hemphill, M. Lassiter, and M. E. Horwitz. “Polyoma Virus Is The Principal Cause Of Cystitis Following Alemtuzumab-Based Allogeneic Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, 16:S319–S319. Elsevier BV, 2010. https://doi.org/10.1016/j.bbmt.2009.12.487.Full Text
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Page, K. M., T. Gentry, K. Shoulars, M. E. Horwitz, N. Herrmann, N. Meadows, B. Philipps, A. Balber, and J. Kurtzberg. “Aldehyde Dehydrogenase Cell Dosing Predicts The Dominating Cord In Double Cord Blood Transplantation.” In Biology of Blood and Marrow Transplantation, 16:S267–68. Elsevier BV, 2010. https://doi.org/10.1016/j.bbmt.2009.12.340.Full Text
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Gasparetto, Cristina, Mitchell E. Horwitz, Jon P. Gockerman, Carlos M. de Castro, Joseph O. Moore, Clay A. Smith, Patty Davis, et al. “Campath-1H May Have Activity in the Treatment of Multiple Myeloma.” In Blood, 104:4931–4931. American Society of Hematology, 2004. https://doi.org/10.1182/blood.v104.11.4931.4931.Full Text
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Ryser, M. F., S. Brenner, N. Whiting-Theobald, R. Lehmann, U. Choi, G. F. Linton, E. Kang, et al. “Insertional analyses in rhesus monkey blood cells after non-myeloablative hematopoietic stem cell marking with a therapeutic onco-retroviral vector for X-linked chronic granulomatous disease.” In Molecular Therapy, 9:S350–S350. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004.Link to Item
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Gasparetto, C., N. J. Chao, M. E. Horwitz, J. O. Moore, C. DeCastro, J. Gockerman, K. Sullivan, et al. “Pharmacokinetics of subcutaneous alemtuzumab in a patient with myeloma.” In Blood, 102:385B-385B. AMER SOC HEMATOLOGY, 2003.Link to Item
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Goggins, T. F., D. A. Rizzieri, R. Prosnitz, C. Gasparetto, G. Long, M. E. Horwitz, K. Sullivan, et al. “One day preparative regimen for allogeneic non-myeloablative stem cell transplantation (NMSCT) using 3-5/6 HLA matched related donors.” In Blood, 102:476B-477B. AMER SOC HEMATOLOGY, 2003.Link to Item
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Rizzieri, D. A., L. P. Koh, G. D. Long, A. S. Lagoo, C. Gasparatto, J. J. Vredenburgh, P. J. Buckley, et al. “Clinical outcome and immune reconstitution following alemtuzumab T cell depleted nonmyeloablative allogeneic immunotherapy from HLA matched siblings.” In Blood, 102:238A-239A. AMER SOC HEMATOLOGY, 2003.Link to Item
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