Mitchell Eric Horwitz | Scholars@Duke

Mitchell Eric Horwitz
Professor of Medicine

Allogeneic stem cell transplantation using umbilical cord blood grafts; Allogenic stem cell transplantation for Sickle Cell Disease; Prevention of acute graft versus host disease through donor stem cell graft manipulation; Improving immune recovery following alternative donor stem cell transplantation using donor graft manipulation or third party thymus transplantation.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2016
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2003
Affiliate of the Duke Regeneration Center, Regeneration Next Initiative, Basic Science Departments 2021

Contact Information

2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
mitchell.horwitz@duke.edu (919) 668-1000

Background
Education, Training, & Certifications
- Medical Resident, Medicine, Northwestern University 1992 - 1995
- M.D., Rush University 1992
Previous Appointments & Affiliations
- Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2013 - 2016
- Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2010 - 2013
- Assistant Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2003 - 2009
- Instructor, Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2003
Recognition
In the News
- DEC 5, 2018 Duke Health News
  
  Expanded Cord Blood Shows Potential for Use in Adult Bone Marrow Transplants
Research
Selected Grants
External Relationships
- CareDx
- Equillium
- Gamida-Cell, Ltd.
- Kadmon Corporation
- Magenta Therapeutics
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Koning, Coco de, Weiyang Tao, Amelia Lacna, Karin van Veghel, Mitchell E. Horwitz, Guillermo Sanz, Madan H. Jagasia, et al. “Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation.” Bone Marrow Transplant 56, no. 11 (November 2021): 2826–33. https://doi.org/10.1038/s41409-021-01417-4.
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  - Horwitz, Mitchell E., Patrick J. Stiff, Corey Cutler, Claudio Brunstein, Rabi Hanna, Richard T. Maziarz, Andrew R. Rezvani, et al. “Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study.” Blood 138, no. 16 (October 2021): 1429–40. https://doi.org/10.1182/blood.2021011719.
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  - Herrera, Alex F., Kwang Woo Ahn, Carlos Litovich, Yue Chen, Amer Assal, Qaiser Bashir, Ruthee-Lu Bayer, et al. “Autologous and allogeneic hematopoietic cell transplantation for diffuse large B-cell lymphoma-type Richter syndrome.” Blood Adv 5, no. 18 (September 28, 2021): 3528–39. https://doi.org/10.1182/bloodadvances.2021004865.
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  - Islam, Prioty, Helen Tang, Haesu Jin, Felicia Cao, Lauren M. Bohannon, Yi Ren, Nelson J. Chao, et al. “Female Sex Is Associated with Improved Long-Term Survival Following Allogeneic Hematopoietic Stem Cell Transplantation.” Transplant Cell Ther 27, no. 9 (September 2021): 784.e1-784.e7. https://doi.org/10.1016/j.jtct.2021.06.012.
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  - Bohannon, Lauren, Helen Tang, Kristin Page, Yi Ren, Sin-Ho Jung, Alexandra Artica, Anne Britt, et al. “Decreased Mortality in 1-Year Survivors of Umbilical Cord Blood Transplant vs. Matched Related or Matched Unrelated Donor Transplant in Patients with Hematologic Malignancies.” Transplant Cell Ther 27, no. 8 (August 2021): 669.e1-669.e8. https://doi.org/10.1016/j.jtct.2021.05.002.
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  - Ponce, Doris M., Ioannis Politikos, Amin Alousi, Paul A. Carpenter, Filippo Milano, Margaret L. MacMillan, Juliet N. Barker, Mitchell E. Horwitz, and Mitchell E. American Society for Transplantation and Cellular Therapy Cord Blood Special Interest Group. “Guidelines for the Prevention and Management of Graft-versus-Host Disease after Cord Blood Transplantation.” Transplantation and Cellular Therapy 27, no. 7 (July 2021): 540–44. https://doi.org/10.1016/j.jtct.2021.03.012.
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  - Pabon, Cindy M., Zhiguo Li, Therese Hennig, Carlos de Castro, Jadee L. Neff, Mitchell E. Horwitz, Thomas W. LeBlanc, et al. “Morphologic leukemia-free state in acute myeloid leukemia is sufficient for successful allogeneic hematopoietic stem cell transplant.” Blood Cancer J 11, no. 5 (May 16, 2021): 92. https://doi.org/10.1038/s41408-021-00481-9.
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  - Giri, Vinay K., Kristin G. Kegerreis, Yi Ren, Lauren M. Bohannon, Erica Lobaugh-Jin, Julia A. Messina, Anita Matthews, et al. “Chlorhexidine Gluconate Bathing Reduces the Incidence of Bloodstream Infections in Adults Undergoing Inpatient Hematopoietic Cell Transplantation.” Transplant Cell Ther 27, no. 3 (March 2021): 262.e1-262.e11. https://doi.org/10.1016/j.jtct.2021.01.004.
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  - Racioppi, Alessandro, Tara Dalton, Sendhilnathan Ramalingam, Kristi Romero, Yi Ren, Lauren Bohannon, Consuelo Arellano, et al. “Assessing the Feasibility of a Novel mHealth App in Hematopoietic Stem Cell Transplant Patients.” Transplant Cell Ther 27, no. 2 (February 2021): 181.e1-181.e9. https://doi.org/10.1016/j.jtct.2020.10.017.
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  - Maung, Ko K., Benny J. Chen, Ian Barak, Zhiguo Li, David A. Rizzieri, Cristina Gasparetto, Keith M. Sullivan, et al. “Phase I dose escalation study of naive T-cell depleted donor lymphocyte infusion following allogeneic stem cell transplantation.” Bone Marrow Transplant 56, no. 1 (January 2021): 137–43. https://doi.org/10.1038/s41409-020-0991-5.
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  - Dillon, Laura W., Gege Gui, Brent R. Logan, Mingwei Fei, Jack Ghannam, Yuesheng Li, Abel Licon, et al. “Impact of Conditioning Intensity and Genomics on Relapse After Allogeneic Transplantation for Patients With Myelodysplastic Syndrome.” Jco Precis Oncol 5 (2021). https://doi.org/10.1200/PO.20.00355.
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  - Ramalingam, Sendhilnathan, Sharareh Siamakpour-Reihani, Lauren Bohannan, Yi Ren, Alexander Sibley, Jeff Sheng, Li Ma, et al. “A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant.” Plos One 16, no. 6 (2021): e0252995. https://doi.org/10.1371/journal.pone.0252995.
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  - Smith, Patrick, Jillian C. Thompson, Elena Perea, Brian Wasserman, Lauren Bohannon, Alessandro Racioppi, Taewoong Choi, et al. “Clinical and Neuroimaging Correlates of Post-Transplant Delirium.” Biol Blood Marrow Transplant 26, no. 12 (December 2020): 2323–28. https://doi.org/10.1016/j.bbmt.2020.09.016.
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  - Scaradavou, Andromachi, Scott T. Avecilla, Joann Tonon, Ioannis Politikos, Mitchell E. Horwitz, Joanne Kurtzberg, Filippo Milano, Juliet N. Barker, and Juliet N. American Society for Transplantation and Cellular Therapy Cord Blood Special Interest Group. “Guidelines for Cord Blood Unit Thaw and Infusion.” Biol Blood Marrow Transplant 26, no. 10 (October 2020): 1780–83. https://doi.org/10.1016/j.bbmt.2020.06.018.
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  - Foster, Gena G., Michael J. Grant, Samantha M. Thomas, Blake Cameron, Doug Raiff, Kelly Corbet, Gavin Loitsch, Christopher Ferreri, and Mitchell Horwitz. “Treatment with Foscarnet after Allogeneic Hematopoietic Cell Transplant (Allo-HCT) Is Associated with Long-Term Loss of Renal Function.” Biol Blood Marrow Transplant 26, no. 9 (September 2020): 1597–1606. https://doi.org/10.1016/j.bbmt.2020.05.007.
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  - Fuchs, Ephraim J., Paul V. O’Donnell, Mary Eapen, Brent R. Logan, Joseph H. Antin, Peter Dawson, Steven M. Devine, et al. “Double unrelated umbilical cord blood versus HLA-haploidentical bone marrow transplantation (BMT CTN 1101).” Blood, August 31, 2020. https://doi.org/10.1182/blood.2020007535.
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  - Saad, Ayman, Marcos de Lima, Sarah Anand, Vijaya Raj Bhatt, Ryan Bookout, George Chen, Daniel Couriel, et al. “Hematopoietic Cell Transplantation, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 18, no. 5 (May 1, 2020): 599–634. https://doi.org/10.6004/jnccn.2020.0021.
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  - Hourigan, Christopher S., Laura W. Dillon, Gege Gui, Brent R. Logan, Mingwei Fei, Jack Ghannam, Yuesheng Li, et al. “Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease.” J Clin Oncol 38, no. 12 (April 20, 2020): 1273–83. https://doi.org/10.1200/JCO.19.03011.
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  - Saullo, Jennifer L., Yanhong Li, Julia A. Messina, Jillian Thompson, Tara Dalton, Vinay K. Giri, Shelby D. Reed, et al. “Cytomegalovirus in Allogeneic Hematopoietic Transplantation: Impact on Costs and Clinical Outcomes Using a Preemptive Strategy.” Biol Blood Marrow Transplant 26, no. 3 (March 2020): 568–80. https://doi.org/10.1016/j.bbmt.2019.11.005.
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  - Maung, Ko, Sendhilnathan Ramalingam, Mohammad Chaudhry, Yi Ren, Sin-Ho Jung, Kristi Romero, Kelly Corbet, et al. “Pre-transplant hepatic steatosis (fatty liver) is associated with chronic graft-vs-host disease but not mortality.” Plos One 15, no. 9 (2020): e0238824. https://doi.org/10.1371/journal.pone.0238824.
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  - Islam, Prioty, and Mitchell E. Horwitz. “Small-molecule nicotinamide for ex vivo expansion of umbilical cord blood.” Experimental Hematology 80 (December 2019): 11–15. https://doi.org/10.1016/j.exphem.2019.11.006.
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  - Horwitz, Mitchell E. “Intestinal Acute Graft-versus-Host Disease: A Bug Highway to the Bloodstream.” Biol Blood Marrow Transplant 25, no. 8 (August 2019): e250–51. https://doi.org/10.1016/j.bbmt.2019.06.011.
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  - Cardones, Adela R., Keith M. Sullivan, Cindy Green, Nelson J. Chao, Krista Rowe-Nichols, Lionel L. Bañez, Claude S. Burton, et al. “Interrater Reliability of Clinical Grading Measures for Cutaneous Chronic Graft-vs-Host Disease.” Jama Dermatol 155, no. 7 (July 1, 2019): 833–37. https://doi.org/10.1001/jamadermatol.2018.5459.
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  - Maung, Ko K., and Mitchell E. Horwitz. “Current and future perspectives on allogeneic transplantation using ex vivo expansion or manipulation of umbilical cord blood cells.” Int J Hematol 110, no. 1 (July 2019): 50–58. https://doi.org/10.1007/s12185-019-02670-6.
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  - Chen, Yi-Bin, Jennifer Le-Rademacher, Ruta Brazauskas, Deidre M. Kiefer, Mehdi Hamadani, John F. DiPersio, Mark R. Litzow, et al. “Plerixafor alone for the mobilization and transplantation of HLA-matched sibling donor hematopoietic stem cells.” Blood Adv 3, no. 6 (March 26, 2019): 875–83. https://doi.org/10.1182/bloodadvances.2018027599.
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  - Horwitz, Mitchell E., Stephen Wease, Beth Blackwell, David Valcarcel, Francesco Frassoni, Jaap Jan Boelens, Stefan Nierkens, et al. “Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide.” J Clin Oncol 37, no. 5 (February 10, 2019): 367–74. https://doi.org/10.1200/JCO.18.00053.
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  - Spellecy, Ryan, Sergey Tarima, Ellen Denzen, Heather Moore, Sunil Abhyankar, Peter Dawson, Amy Foley, et al. “Easy-to-Read Informed Consent Form for Hematopoietic Cell Transplantation Clinical Trials: Results from the Blood and Marrow Transplant Clinical Trials Network 1205 Study.” Biol Blood Marrow Transplant 24, no. 10 (October 2018): 2145–51. https://doi.org/10.1016/j.bbmt.2018.04.014.
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  - Micallef, Ivana N., Patrick J. Stiff, Auayporn P. Nademanee, Richard T. Maziarz, Mitchell E. Horwitz, Edward A. Stadtmauer, Jonathan L. Kaufman, et al. “Plerixafor Plus Granulocyte Colony-Stimulating Factor for Patients with Non-Hodgkin Lymphoma and Multiple Myeloma: Long-Term Follow-Up Report.” Biol Blood Marrow Transplant 24, no. 6 (June 2018): 1187–95. https://doi.org/10.1016/j.bbmt.2018.01.039.
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  - Sullivan, Keith M., Mitchell Horwitz, Ifeyinwa Osunkwo, Nirmish Shah, and John J. Strouse. “Shared Decision-Making in Hematopoietic Stem Cell Transplantation for Sickle Cell Disease.” Biol Blood Marrow Transplant 24, no. 5 (May 2018): 883–84. https://doi.org/10.1016/j.bbmt.2018.04.001.
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  - Jones, Roy B., Charles Martinez, Navneet S. Majhail, Matthew Prestegaard, Martin Maiers, Mitchell Horwitz, and Krishna Komanduri. “Stem Cell Transplantation and Informatics: Current Considerations.” Biol Blood Marrow Transplant 24, no. 4 (April 2018): 659–65. https://doi.org/10.1016/j.bbmt.2017.12.792.
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  - Grant, Michael J., and Mitchell E. Horwitz. “HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature.” Case Rep Transplant 2018 (2018): 2376483. https://doi.org/10.1155/2018/2376483.
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  - Sivaraj, D., W. Bacon, G. D. Long, D. A. Rizzieri, M. E. Horwitz, K. M. Sullivan, Y. Kang, Z. Li, N. J. Chao, and C. Gasparetto. “High-dose BCNU/Melphalan conditioning regimen before autologous stem cell transplantation in newly diagnosed multiple myeloma.” Bone Marrow Transplant 53, no. 1 (January 2018): 34–38. https://doi.org/10.1038/bmt.2017.208.
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  - Soiffer, Robert J., Haesook T. Kim, Joseph McGuirk, Mitchell E. Horwitz, Laura Johnston, Mrinal M. Patnaik, Witold Rybka, et al. “Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation.” J Clin Oncol 35, no. 36 (December 20, 2017): 4003–11. https://doi.org/10.1200/JCO.2017.75.8177.
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  - Huang, Li-Wen, Wendi Bacon, Constance Cirrincione, Bercedis Peterson, Gwynn Long, David Rizzieri, Keith M. Sullivan, et al. “Efficacy and safety of high-dose chemotherapy with autologous stem cell transplantation in senior versus younger adults with newly diagnosed multiple myeloma.” Hematol Oncol 35, no. 4 (December 2017): 752–59. https://doi.org/10.1002/hon.2379.
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  - Poe, Jonathan C., Wei Jia, Hsuan Su, Sarah Anand, Jeremy J. Rose, Prasanthi V. Tata, Amy N. Suthers, et al. “An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.” Blood 130, no. 19 (November 9, 2017): 2131–45. https://doi.org/10.1182/blood-2017-05-782466.
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  - Stover, Jessica T., J Ryan Shaw, Maragatha Kuchibhatla, Mitchell E. Horwitz, and Ashley M. Engemann. “Evaluation of Hematopoietic Stem Cell Mobilization Rates with Early Plerixafor Administration for Adult Stem Cell Transplantation.” Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 23, no. 8 (August 2017): 1290–94. https://doi.org/10.1016/j.bbmt.2017.04.007.
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  - Anand, Sarah, Samantha Thomas, Terry Hyslop, Janet Adcock, Kelly Corbet, Cristina Gasparetto, Richard Lopez, et al. “Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization.” Biol Blood Marrow Transplant 23, no. 7 (July 2017): 1151–57. https://doi.org/10.1016/j.bbmt.2017.04.001.
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  - Barker, Juliet N., Joanne Kurtzberg, Karen Ballen, Michael Boo, Claudio Brunstein, Corey Cutler, Mitchell Horwitz, et al. “Optimal Practices in Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies.” Biol Blood Marrow Transplant 23, no. 6 (June 2017): 882–96. https://doi.org/10.1016/j.bbmt.2017.03.006.
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  - Scott, Bart L., Marcelo C. Pasquini, Brent R. Logan, Juan Wu, Steven M. Devine, David L. Porter, Richard T. Maziarz, et al. “Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.” J Clin Oncol 35, no. 11 (April 10, 2017): 1154–61. https://doi.org/10.1200/JCO.2016.70.7091.
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  - Sivaraj, Dharshan, Michael M. Green, Zhiguo Li, Anthony D. Sung, Stefanie Sarantopoulos, Yubin Kang, Gwynn D. Long, et al. “Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma.” Biol Blood Marrow Transplant 23, no. 2 (February 2017): 262–68. https://doi.org/10.1016/j.bbmt.2016.11.010.
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  - Sung, Anthony, and Mitchell Horwitz. “Reply to Strahilevitz and Shapira.” Clin Infect Dis, December 12, 2016. https://doi.org/10.1093/cid/ciw813.
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  - Sung, Anthony D., Julia A. M. Sung, Samantha Thomas, Terry Hyslop, Cristina Gasparetto, Gwynn Long, David Rizzieri, et al. “Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial.” Clin Infect Dis 63, no. 8 (October 15, 2016): 999–1006. https://doi.org/10.1093/cid/ciw451.
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  - Green, Michael M. B., Nelson Chao, Saurabh Chhabra, Kelly Corbet, Cristina Gasparetto, Ari Horwitz, Zhiguo Li, et al. “Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.” J Hematol Oncol 9, no. 1 (August 17, 2016): 71. https://doi.org/10.1186/s13045-016-0301-2.
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  - Flowers, Christopher R., Luciano J. Costa, Marcelo C. Pasquini, Jennifer Le-Rademacher, Michael Lill, Tsiporah B. Shore, William Vaughan, et al. “Efficacy of Pharmacokinetics-Directed Busulfan, Cyclophosphamide, and Etoposide Conditioning and Autologous Stem Cell Transplantation for Lymphoma: Comparison of a Multicenter Phase II Study and CIBMTR Outcomes.” Biol Blood Marrow Transplant 22, no. 7 (July 2016): 1197–1205. https://doi.org/10.1016/j.bbmt.2016.03.018.
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  - Horwitz, Mitchell E. “Ex Vivo Expansion or Manipulation of Stem Cells to Improve Outcome of Umbilical Cord Blood Transplantation.” Curr Hematol Malig Rep 11, no. 1 (February 2016): 12–18. https://doi.org/10.1007/s11899-015-0297-7.
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  - Anderlini, Paolo, Juan Wu, Iris Gersten, Marian Ewell, Jakob Tolar, Joseph H. Antin, Roberta Adams, et al. “Cyclophosphamide conditioning in patients with severe aplastic anaemia given unrelated marrow transplantation: a phase 1-2 dose de-escalation study.” Lancet Haematol 2, no. 9 (September 2015): e367–75. https://doi.org/10.1016/S2352-3026(15)00147-7.
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  - Horwitz, Mitchell E., and Francesco Frassoni. “Improving the outcome of umbilical cord blood transplantation through ex vivo expansion or graft manipulation.” Cytotherapy 17, no. 6 (June 2015): 730–38. https://doi.org/10.1016/j.jcyt.2015.02.004.
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  - Tuchman, Sascha A., Wendi A. Bacon, Li-Wen Huang, Gwynn Long, David Rizzieri, Mitchell Horwitz, John P. Chute, et al. “Cyclophosphamide-based hematopoietic stem cell mobilization before autologous stem cell transplantation in newly diagnosed multiple myeloma.” J Clin Apher 30, no. 3 (June 2015): 176–82. https://doi.org/10.1002/jca.21360.
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  - Barker, Juliet N., Mingwei Fei, Chatchada Karanes, Mitchell Horwitz, Steven Devine, Tamila L. Kindwall-Keller, Jennifer Holter, et al. “Results of a prospective multicentre myeloablative double-unit cord blood transplantation trial in adult patients with acute leukaemia and myelodysplasia.” Br J Haematol 168, no. 3 (February 2015): 405–12. https://doi.org/10.1111/bjh.13136.
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  - Kelsey, C. R., J. M. Scott, A. Lane, E. Schwitzer, M. J. West, S. Thomas, J. E. Herndon, et al. “Cardiopulmonary exercise testing prior to myeloablative allo-SCT: a feasibility study.” Bone Marrow Transplant 49, no. 10 (October 2014): 1330–36. https://doi.org/10.1038/bmt.2014.159.
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  - Horwitz, Mitchell E., Nelson J. Chao, David A. Rizzieri, Gwynn D. Long, Keith M. Sullivan, Cristina Gasparetto, John P. Chute, et al. “Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment.” J Clin Invest 124, no. 7 (July 2014): 3121–28. https://doi.org/10.1172/JCI74556.
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  - Allen, Jessica L., Prasanthi V. Tata, Matthew S. Fore, Jenna Wooten, Sharmistha Rudra, Allison M. Deal, Andrew Sharf, et al. “Increased BCR responsiveness in B cells from patients with chronic GVHD.” Blood 123, no. 13 (March 27, 2014): 2108–15. https://doi.org/10.1182/blood-2013-10-533562.
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  - Kanda, Junya, Gwynn D. Long, Cristina Gasparetto, Mitchell E. Horwitz, Keith M. Sullivan, John P. Chute, Ashley Morris, et al. “Reduced-intensity allogeneic transplantation using alemtuzumab from HLA-matched related, unrelated, or haploidentical related donors for patients with hematologic malignancies.” Biol Blood Marrow Transplant 20, no. 2 (February 2014): 257–63. https://doi.org/10.1016/j.bbmt.2013.11.010.
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  - Sung, A. D., D. T. Grima, L. M. Bernard, S. Brown, G. Carrum, L. Holmberg, M. E. Horwitz, et al. “Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone.” Bone Marrow Transplantation 48, no. 11 (November 1, 2013): 1444–49. https://doi.org/10.1038/bmt.2013.80.
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  - Sung, A. D., D. T. Grima, L. M. Bernard, S. Brown, G. Carrum, L. Holmberg, M. E. Horwitz, et al. “Outcomes and costs of autologous stem cell mobilization with chemotherapy plus G-CSF vs G-CSF alone.” Bone Marrow Transplant 48, no. 11 (November 2013): 1444–49. https://doi.org/10.1038/bmt.2013.80.
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  - Kanda, J., L. Kaynar, Y. Kanda, V. K. Prasad, S. H. Parikh, L. Lan, T. Shen, et al. “Pre-engraftment syndrome after myeloablative dual umbilical cord blood transplantation: risk factors and response to treatment.” Bone Marrow Transplantation 48, no. 7 (July 2013): 926–31. https://doi.org/10.1038/bmt.2012.279.
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  - Held, Lauren A., David Rizzieri, Gwynn D. Long, Jon P. Gockerman, Louis F. Diehl, Carlos M. de Castro, Joseph O. Moore, Mitchell E. Horwitz, Nelson J. Chao, and Cristina Gasparetto. “A Phase I study of arsenic trioxide (Trisenox), ascorbic acid, and bortezomib (Velcade) combination therapy in patients with relapsed/refractory multiple myeloma.” Cancer Invest 31, no. 3 (March 2013): 172–76. https://doi.org/10.3109/07357907.2012.756109.
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  - Spasojevic, Ivan, Ligia R. S. da Costa, Mitchell E. Horwitz, Gwynn D. Long, Keith M. Sullivan, John P. Chute, Cristina Gasparetto, Ashley Morris, Nelson J. Chao, and David A. Rizzieri. “Mini test dose of intravenous busulfan (busulfex(®)) in allogeneic non-myeloablative stem cell transplantation, followed by liquid chromatography tandem-mass spectrometry.” Cancer Invest 30, no. 9 (November 2012): 679–82. https://doi.org/10.3109/07357907.2012.726386.
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  - Kanda, Junya, Lun-Wei Chiou, Paul Szabolcs, Gregory D. Sempowski, David A. Rizzieri, Gwynn D. Long, Keith M. Sullivan, et al. “Immune recovery in adult patients after myeloablative dual umbilical cord blood, matched sibling, and matched unrelated donor hematopoietic cell transplantation.” Biol Blood Marrow Transplant 18, no. 11 (November 2012): 1664-1676.e1. https://doi.org/10.1016/j.bbmt.2012.06.005.
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  - Horwitz, M. E., G. Long, P. Holman, E. Libby, G. C. Calandra, and J. R. Schriber. “Efficacy and safety of hematopoietic stem cell remobilization with plerixafor+G-CSF in adult patients with germ cell tumors.” Bone Marrow Transplant 47, no. 10 (October 2012): 1283–86. https://doi.org/10.1038/bmt.2012.21.
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  - Eapen, Mary, Kwang Woo Ahn, Paul J. Orchard, Morton J. Cowan, Stella M. Davies, Anders Fasth, Anna Hassebroek, et al. “Long-term survival and late deaths after hematopoietic cell transplantation for primary immunodeficiency diseases and inborn errors of metabolism.” Biol Blood Marrow Transplant 18, no. 9 (September 2012): 1438–45. https://doi.org/10.1016/j.bbmt.2012.03.003.
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  - Horwitz, M. E., J. P. Chute, C. Gasparetto, G. D. Long, C. McDonald, A. Morris, D. A. Rizzieri, K. M. Sullivan, and N. J. Chao. “Preemptive dosing of plerixafor given to poor stem cell mobilizers on day 5 of G-CSF administration.” Bone Marrow Transplant 47, no. 8 (August 2012): 1051–55. https://doi.org/10.1038/bmt.2011.217.
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  - Tolar, Jakub, H Joachim Deeg, Sally Arai, Mitchell Horwitz, Joseph H. Antin, John M. McCarty, Roberta H. Adams, et al. “Fludarabine-based conditioning for marrow transplantation from unrelated donors in severe aplastic anemia: early results of a cyclophosphamide dose deescalation study show life-threatening adverse events at predefined cyclophosphamide dose levels.” Biol Blood Marrow Transplant 18, no. 7 (July 2012): 1007–11. https://doi.org/10.1016/j.bbmt.2012.04.014.
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  - Chen, D. -. F., V. K. Prasad, G. Broadwater, N. L. Reinsmoen, A. DeOliveira, A. Clark, K. M. Sullivan, et al. “Differential impact of inhibitory and activating Killer Ig-Like Receptors (KIR) on high-risk patients with myeloid and lymphoid malignancies undergoing reduced intensity transplantation from haploidentical related donors.” Bone Marrow Transplant 47, no. 6 (June 2012): 817–23. https://doi.org/10.1038/bmt.2011.181.
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  - Kanda, J., M. E. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. P. Chute, A. Morris, et al. “Outcomes of a 1-day nonmyeloablative salvage regimen for patients with primary graft failure after allogeneic hematopoietic cell transplantation.” Bone Marrow Transplant 47, no. 5 (May 2012): 700–705. https://doi.org/10.1038/bmt.2011.158.
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  - Kelsey, Chris R., Mitchell E. Horwitz, Junzo P. Chino, Oana Craciunescu, Beverly Steffey, Rodney J. Folz, Nelson J. Chao, David A. Rizzieri, and Lawrence B. Marks. “Severe pulmonary toxicity after myeloablative conditioning using total body irradiation: an assessment of risk factors.” Int J Radiat Oncol Biol Phys 81, no. 3 (November 1, 2011): 812–18. https://doi.org/10.1016/j.ijrobp.2010.06.058.
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  - Kanda, Junya, David A. Rizzieri, Cristina Gasparetto, Gwynn D. Long, John P. Chute, Keith M. Sullivan, Ashley Morris, et al. “Adult dual umbilical cord blood transplantation using myeloablative total body irradiation (1350 cGy) and fludarabine conditioning.” Biol Blood Marrow Transplant 17, no. 6 (June 2011): 867–74. https://doi.org/10.1016/j.bbmt.2010.09.009.
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  - Palmer, J., T. Goggins, G. Broadwater, N. Chao, M. Horwitz, A. Beaven, K. Sullivan, R. E. Coleman, and D. Rizzieri. “Early post transplant (F-18) 2-fluoro-2-deoxyglucose positron emission tomography does not predict outcome for patients undergoing auto-SCT in non-Hodgkin and Hodgkin lymphoma.” Bone Marrow Transplant 46, no. 6 (June 2011): 847–51. https://doi.org/10.1038/bmt.2010.203.
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  - Wang, Endi, Charles Blake Hutchinson, Qin Huang, Chuanyi Mark Lu, Jennifer Crow, Frances F. Wang, Siby Sebastian, et al. “Donor cell-derived leukemias/myelodysplastic neoplasms in allogeneic hematopoietic stem cell transplant recipients: a clinicopathologic study of 10 cases and a comprehensive review of the literature.” Am J Clin Pathol 135, no. 4 (April 2011): 525–40. https://doi.org/10.1309/AJCPPJUQ9DNR1GHP.
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  - Craciunescu, Oana I., Beverly A. Steffey, Chris R. Kelsey, Nicole A. Larrier, Cathy J. Paarz-Largay, Robert G. Prosnitz, Nelson Chao, et al. “Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial.” Int J Radiat Oncol Biol Phys 79, no. 4 (March 15, 2011): 1248–55. https://doi.org/10.1016/j.ijrobp.2010.05.036.
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  - Horwitz, Mitchell E. “Reduced intensity versus myeloablative allogeneic stem cell transplantation for the treatment of acute myeloid leukemia, myelodysplastic syndrome and acute lymphoid leukemia.” Curr Opin Oncol 23, no. 2 (March 2011): 197–202. https://doi.org/10.1097/CCO.0b013e328342b82a.
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  - Turbeville, Sean, Helen Nicely, J Douglas Rizzo, Tanya L. Pedersen, Paul J. Orchard, Mitchell E. Horwitz, Edwin M. Horwitz, Paul Veys, Carmem Bonfim, and Amal Al-Seraihy. “Clinical outcomes following hematopoietic stem cell transplantation for the treatment of mucopolysaccharidosis VI.” Mol Genet Metab 102, no. 2 (February 2011): 111–15. https://doi.org/10.1016/j.ymgme.2010.09.010.
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  - Rizzieri, David A., Christopher Crout, Robert Storms, Jared Golob, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan, et al. “Feasibility of low-dose interleukin-2 therapy following T-cell-depleted nonmyeloablative allogeneic hematopoietic stem cell transplantation from HLA-matched or -mismatched family member donors.” Cancer Invest 29, no. 1 (January 2011): 56–61. https://doi.org/10.3109/07357907.2010.535055.
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  - Horwitz, M. E., and N. Chao. “Umbilical cord blood transplantation for treatment of non-malignant disorders.” Cellular Therapy and Transplantation 2, no. 7 (December 1, 2010). https://doi.org/10.3205/ctt-2010-en-000069.01.
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  - Rizzieri, David A., Robert Storms, Dong-Feng Chen, Gwynn Long, Yiping Yang, Daniel A. Nikcevich, Cristina Gasparetto, et al. “Natural killer cell-enriched donor lymphocyte infusions from A 3-6/6 HLA matched family member following nonmyeloablative allogeneic stem cell transplantation.” Biol Blood Marrow Transplant 16, no. 8 (August 2010): 1107–14. https://doi.org/10.1016/j.bbmt.2010.02.018.
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  - Crout, Christopher A., Liang-Piu Koh, Jon P. Gockerman, Joseph O. Moore, Carlos Decastro, Gwynn D. Long, Louis Diehl, et al. “Overcoming drug resistance in mantle cell lymphoma using a combination of dose-dense and intense therapy.” Cancer Invest 28, no. 6 (July 2010): 654–60. https://doi.org/10.3109/07357901003631015.
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  - Horwitz, Mitchell E., and Nelson Chao. “Non-myeloablative umbilical cord blood transplantation.” Best Pract Res Clin Haematol 23, no. 2 (June 2010): 231–36. https://doi.org/10.1016/j.beha.2010.06.001.
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  - Gasparetto, Cristina, Jon P. Gockerman, Louis F. Diehl, Carlos M. de Castro, Joseph O. Moore, Gwynn D. Long, Mitchell E. Horwitz, et al. “"Short course" bortezomib plus melphalan and prednisone as induction prior to transplant or as frontline therapy for nontransplant candidates in patients with previously untreated multiple myeloma.” Biol Blood Marrow Transplant 16, no. 1 (January 2010): 70–77. https://doi.org/10.1016/j.bbmt.2009.08.017.
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  - DiPersio, John F., Edward A. Stadtmauer, Auayporn Nademanee, Ivana N. M. Micallef, Patrick J. Stiff, Jonathan L. Kaufman, Richard T. Maziarz, et al. “Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma.” Blood 113, no. 23 (June 4, 2009): 5720–26. https://doi.org/10.1182/blood-2008-08-174946.
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  - Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P134 A phase II pilot study of sorafenib in patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70215-2.
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  - Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P129 A pilot study of decitabine in combination with arsenic trioxide for patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70210-3.
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  - Qasim, Waseem, Marina Cavazzana-Calvo, E Graham Davies, Jeffery Davis, Michel Duval, Gretchen Eames, Nuno Farinha, et al. “Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency.” Pediatrics 123, no. 3 (March 2009): 836–40. https://doi.org/10.1542/peds.2008-1191.
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  - Horwitz, M. E., G. Tunes da Silva, M. Eapen, and E. M. Horwitz. “Survival Following Allogeneic Stem Cell Transplantation for Congenital Immunodeficiency and Metabolic Disorders.” Biology of Blood and Marrow Transplantation 15, no. 2 (February 2009): 78–78. https://doi.org/10.1016/j.bbmt.2008.12.240.
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  - Rizzieri, D. A., P. Dev, G. D. Long, C. Gasparetto, K. M. Sullivan, Ml Horwitz, J. Chute, and N. J. Chao. “Response and toxicity of donor lymphocyte infusions following T-cell depleted non-myeloablative allogeneic hematopoietic SCT from 3-6/6 HLA matched donors.” Bone Marrow Transplant 43, no. 4 (February 2009): 327–33. https://doi.org/10.1038/bmt.2008.321.
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  - Horwitz, Mitchell E., Ashley Morris, Cristina Gasparetto, Keith Sullivan, Gwynn Long, John Chute, David Rizzieri, Jackie McPherson, and Nelson Chao. “Myeloablative intravenous busulfan/fludarabine conditioning does not facilitate reliable engraftment of dual umbilical cord blood grafts in adult recipients.” Biol Blood Marrow Transplant 14, no. 5 (May 2008): 591–94. https://doi.org/10.1016/j.bbmt.2008.02.016.
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  - Byrne, B. J., M. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. Chute, N. J. Chao, and D. A. Rizzieri. “Outcomes of a second non-myeloablative allogeneic stem cell transplantation following graft rejection.” Bone Marrow Transplant 41, no. 1 (January 2008): 39–43. https://doi.org/10.1038/sj.bmt.1705882.
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  - Uzel, Gulbu, Emilia Tng, Sergio D. Rosenzweig, Amy P. Hsu, Jacqueline M. Shaw, Mitchell E. Horwitz, Gilda F. Linton, et al. “Reversion mutations in patients with leukocyte adhesion deficiency type-1 (LAD-1).” Blood 111, no. 1 (January 1, 2008): 209–18. https://doi.org/10.1182/blood-2007-04-082552.
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  - Horwitz, Mitchell E., Ivan Spasojevic, Ashley Morris, Marilyn Telen, James Essell, Cristina Gasparetto, Keith Sullivan, et al. “Fludarabine-based nonmyeloablative stem cell transplantation for sickle cell disease with and without renal failure: clinical outcome and pharmacokinetics.” Biol Blood Marrow Transplant 13, no. 12 (December 2007): 1422–26. https://doi.org/10.1016/j.bbmt.2007.08.050.
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  - Horwitz, Mitchell E. “Sources of human and murine hematopoietic stem cells.” Curr Protoc Immunol Chapter 22 (November 2007): Unit-22A.2. https://doi.org/10.1002/0471142735.im22a02s79.
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  - Hanson, Kimberly E., L Barth Reller, Joanne Kurtzberg, Mitchell Horwitz, Gwynn Long, and Barbara D. Alexander. “Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens from allogeneic-stem-cell transplant recipients.” J Clin Microbiol 45, no. 6 (June 2007): 1972–73. https://doi.org/10.1128/JCM.02515-06.
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  - Rizzieri, David A., Liang Piu Koh, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan, Mitchell Horwitz, John Chute, et al. “Partially matched, nonmyeloablative allogeneic transplantation: clinical outcomes and immune reconstitution.” J Clin Oncol 25, no. 6 (February 20, 2007): 690–97. https://doi.org/10.1200/JCO.2006.07.0953.
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  - Brenner, Sebastian, Martin F. Ryser, Uimook Choi, Narda Whiting-Theobald, Eberhard Kuhlisch, Gilda Linton, Elizabeth Kang, et al. “Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells.” Mol Ther 14, no. 2 (August 2006): 202–11. https://doi.org/10.1016/j.ymthe.2006.01.015.
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  - Bleesing, Jack J., Margarida M. Souto-Carneiro, William J. Savage, Margaret R. Brown, Cynthia Martinez, Sule Yavuz, Sebastian Brenner, et al. “Patients with chronic granulomatous disease have a reduced peripheral blood memory B cell compartment.” J Immunol 176, no. 11 (June 1, 2006): 7096–7103. https://doi.org/10.4049/jimmunol.176.11.7096.
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  - Horwitz, Mitchell E., and Keith M. Sullivan. “Chronic graft-versus-host disease.” Blood Rev 20, no. 1 (January 2006): 15–27. https://doi.org/10.1016/j.blre.2005.01.007.
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  - Yamashita, Kouhei, Mitchell E. Horwitz, Akua Kwatemaa, Effie Nomicos, Kathleen Castro, Robert Sokolic, Susan F. Foster, et al. “Unique abnormalities of CD4(+) and CD8(+) central memory cells associated with chronic graft-versus-host disease improve after extracorporeal photopheresis.” Biol Blood Marrow Transplant 12, no. 1 Suppl 2 (January 2006): 22–30. https://doi.org/10.1016/j.bbmt.2005.11.004.
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  - Roesler, Joachim, Mitchell E. Horwitz, Capucine Picard, Pierre Bordigoni, Graham Davies, Ewa Koscielniak, Mike Levin, et al. “Hematopoietic stem cell transplantation for complete IFN-gamma receptor 1 deficiency: a multi-institutional survey.” J Pediatr 145, no. 6 (December 2004): 806–12. https://doi.org/10.1016/j.jpeds.2004.08.021.
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  - Chao, Nelson. “Hematopoietic stem cell transplantation.” Curr Opin Hematol 11, no. 6 (November 2004): 373–74. https://doi.org/10.1097/01.moh.0000144500.82861.c0.
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  - Chao, Nelson J., Liang-Piu Koh, Gwynn D. Long, Cristina Gasparetto, Mitchell Horwitz, Ashley Morris, Martha Lassiter, Keith M. Sullivan, and David A. Rizzieri. “Adult recipients of umbilical cord blood transplants after nonmyeloablative preparative regimens.” Biol Blood Marrow Transplant 10, no. 8 (August 2004): 569–75. https://doi.org/10.1016/j.bbmt.2004.05.001.
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  - Yamashita, Kouhei, Uimook Choi, Patricia C. Woltz, Susan F. Foster, Michael C. Sneller, Francis T. Hakim, Daniel H. Fowler, et al. “Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells.” Blood 103, no. 10 (May 15, 2004): 3986–88. https://doi.org/10.1182/blood-2003-09-3286.
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  - Bolan, Charles D., Yu Ying Yau, Herbert C. Cullis, Mitchell E. Horwitz, Crystal L. Mackall, A John Barrett, Harry L. Malech, Nadja N. Rehak, Alan S. Wayne, and Susan F. Leitman. “Pediatric large-volume leukapheresis: a single institution experience with heparin versus citrate-based anticoagulant regimens.” Transfusion 44, no. 2 (February 2004): 229–38. https://doi.org/10.1111/j.1537-2995.2004.00668.x.
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  - Brenner, Sebastian, Narda L. Whiting-Theobald, Gilda F. Linton, Kevin L. Holmes, Mindy Anderson-Cohen, Patrick F. Kelly, Elio F. Vanin, et al. “Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.” Blood 102, no. 8 (October 15, 2003): 2789–97. https://doi.org/10.1182/blood-2002-05-1482.
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  - Horwitz, Mitchell E., Gulbu Uzel, Gilda F. Linton, Judi A. Miller, Margaret R. Brown, Harry L. Malech, and Steven M. Holland. “Persistent Mycobacterium avium infection following nonmyeloablative allogeneic peripheral blood stem cell transplantation for interferon-gamma receptor-1 deficiency.” Blood 102, no. 7 (October 1, 2003): 2692–94. https://doi.org/10.1182/blood-2003-04-1268.
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  - Abo-Zena, Reem A., and Mitchell E. Horwitz. “Immunomodulation in stem-cell transplantation.” Curr Opin Pharmacol 2, no. 4 (August 2002): 452–57. https://doi.org/10.1016/s1471-4892(02)00174-1.
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  - Barron, K. S., C. Wallace, C. Woolfrey CEA, R. M. Laxer, R. Hirsch, M. Horwitz, J. Siegel, et al. “Autologous stem cell transplantation for pediatric rheumatic diseases.” J Rheumatol 28, no. 10 (October 2001): 2337–58.
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  - Savage, W. J., J. J. Bleesing, D. Douek, M. R. Brown, G. M. Linton, H. L. Malech, and M. E. Horwitz. “Lymphocyte reconstitution following non-myeloablative hematopoietic stem cell transplantation follows two patterns depending on age and donor/recipient chimerism.” Bone Marrow Transplant 28, no. 5 (September 2001): 463–71. https://doi.org/10.1038/sj.bmt.1703176.
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  - Horwitz, M. E., A. J. Barrett, M. R. Brown, C. S. Carter, R. Childs, J. I. Gallin, S. M. Holland, et al. “Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft.” N Engl J Med 344, no. 12 (March 22, 2001): 881–88. https://doi.org/10.1056/NEJM200103223441203.
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  - Horwitz, M. E. “Stem-cell transplantation for inherited immunodeficiency disorders.” Pediatr Clin North Am 47, no. 6 (December 2000): 1371–87. https://doi.org/10.1016/s0031-3955(05)70276-5.
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  - Centola, M., G. Wood, D. M. Frucht, J. Galon, M. Aringer, C. Farrell, D. W. Kingma, et al. “The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators.” Blood 95, no. 10 (May 15, 2000): 3223–31.
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  - Horwitz, M. E., H. L. Malech, S. M. Anderson, L. J. Girard, D. M. Bodine, and D. Orlic. “Granulocyte colony-stimulating factor mobilized peripheral blood stem cells enter into G1 of the cell cycle and express higher levels of amphotropic retrovirus receptor mRNA.” Exp Hematol 27, no. 7 (July 1999): 1160–67. https://doi.org/10.1016/s0301-472x(99)00049-1.
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- Conference Papers
  - Smith, Patrick J., Meagan Lew, Yen Lowder, Kristi Romero, Jillian C. Thompson, Lauren Bohannon, Alyssa Pittman, et al. “Cognitive impairment in candidates for allogeneic hematopoietic stem cell transplantation.” In Bone Marrow Transplant, 57:89–94, 2022. https://doi.org/10.1038/s41409-021-01470-z.
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  - Maung, Ko, Nelson Jen An Chao, Kelly Corbet, Ashley Morris Engemann, Cristina Gasparetto, Mitchell Horwitz, Yubin Kang, et al. “CLO20-049: Retrospective Study of Safety and Toxicity Profile Comparison for Propylene Glycol-Free Melphalan (Evomela®) and Generic Melphalan.” In Journal of the National Comprehensive Cancer Network, 18:CLO20-049. Harborside Press, LLC, 2020. https://doi.org/10.6004/jnccn.2019.7412.
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  - Ramalingam, Sendhilnathan, Sharareh Siamakpour-Reihani, Lauren Bohannon, Yi Ren, Alexander Sibley, Andrew Nixon, Jing Lyu, et al. “Phase II Trial of Pasireotide to Prevent GI Toxicity and Acute Gvhd in Allogeneic HSCT.” In Biology of Blood and Marrow Transplantation, 26:S48–49. ELSEVIER SCIENCE INC, 2020.
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  - Poe, Jonathan C., Dadong Zhang, Jichun Xie, Rachel A. DiCioccio, Xiaodi Qin, Jiyuan Fang, Vincent T. Ho, et al. “Single-Cell RNA-Seq Identifies Potentially Pathogenic B Cell Populations That Uniquely Circulate in Patients with Chronic Gvhd.” In Blood, 134:874–874. American Society of Hematology, 2019. https://doi.org/10.1182/blood-2019-130928.
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  - Boelens, Jaap Jan, Coco de Koning, Mitchell E. Horwitz, Guillermo Sanz, Madan Jagasia, John E. Wagner, Patrick J. Stiff, Rabi Hanna, Daniela Cilloni, and Stefan Nierkens. “Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation.” In Blood, 132:2123–2123. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-116700.
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  - Foster, Yevgeniya, Michael J. Grant, Samantha M. Thomas, Blake Cameron, Doug Raiff, Kelly Corbet, Christopher Ferreri, and Mitchell E. Horwitz. “Treatment with Foscarnet after Allogeneic Hematopoietic-Cell Transplant (AlloHCT) Is Associated with Long-Term Loss of Renal Function.” In Blood, 132:4594–4594. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-113189.
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  - Leventhal, Joseph R., John P. Galvin, James Mathew, Lorenzo Gallon, Kadiyala Ravindra, Mitchell E. Horwitz, Michael Abecassis, and Suzanne T. Ildstad. “Use of a Processed Hematopoietic Stem Cell Product (FCRx) in Unmatched Related and Unrelated Donor — Recipient Pairs Is Associated with High Levels of Donor Chimerism and Donor-Specific Tolerance to Kidney Allografts.” In Blood, 132:202–202. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-118832.
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  - Parikh, Suhag, Joel A. Brochstein, Stephen Wease, Paul L. Martin, Mitchell E. Horwitz, Aurelie Schwarzbach, and Joanne Kurtzberg. “A Novel Therapy for Sickle Cell Disease (SCD): Co-Transplantation of Nicord (R) [Ex Vivo Expanded Umbilical Cord Blood (UCB) Progenitor Cells with Nicotinamide] and an Unmanipulated Unrelated UCB Graft Leads to Successful Engraftment and Cure of Severe SCD.” In Biology of Blood and Marrow Transplantation, 24:S157–58. ELSEVIER SCIENCE INC, 2018.
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  - Horwitz, Mitchell E., Daniela Cilloni, David Valcarcel, Francesco Frassoni, Jaap-Jan Boelens, Madan Jagasia, John E. Wagner, et al. “Nicord Single Unit Expanded Umbilical Cord Blood Transplantation (UCBT): Final Results of a Multicenter Phase I/ II Trial.” In Biology of Blood and Marrow Transplantation, 24:S57–S57. Elsevier BV, 2018. https://doi.org/10.1016/j.bbmt.2017.12.628.
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  - Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Gwynn D. Long, Richard Lopez, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Thiotepa, Total Body Irradiation, and Fludarabine Conditioning.” In Biol Blood Marrow Transplant, 23:1949–54, 2017. https://doi.org/10.1016/j.bbmt.2017.06.027.
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  - Parikh, Suhag, Joel Brochstein, Paul L. Martin, Mitchell E. Horwitz, Einat Galamidi, Iddo Peleg, Uri Goshen, et al. “Successful Engraftment of Umbilical Cord Blood (UCB) Cells after Co-Transplantation of Nicord (R) (Ex Vivo Expanded UCB Progenitor Cells with Nicotinamide) and an Unmanipulated UCB Unit after Myeloablative Chemotherapy in Severe Sickle Cell Disease.” In Biology of Blood and Marrow Transplantation, 23:S150–51, 2017.
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  - Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Richard Lopez, Gwynn D. Long, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Total Body Irradiation, Fludarabine, and Thiotepa Conditioning.” In Blood, 128:3395–3395. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.3395.3395.
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  - Parikh, Suhag H., Joel Brochstein, Paul L. Martin, Mitchell E. Horwitz, Einat Galamidi, Iddo Peleg, Uri Goshen, et al. “Successful Engraftment of Donor Umbilical Cord Blood (UCB) Cells after Co-Transplantation of Nicord® (Ex Vivo Expanded UCB Progenitor Cells with Nicotinamide) and a Second Unmanipulated Cord Blood Unit after Myeloablative Chemotherapy in Pediatric Patients with Severe Sickle Cell Disease.” In Blood, 128:3651–3651. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.3651.3651.
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  - Soiffer, Robert J., Haesook T. Kim, Joseph McGuirk, Mitchell E. Horwitz, Laura Johnston, Mrinal M. Patnaik, Witold Rybka, et al. “A Prospective Randomized Double Blind Phase 3 Clinical Trial of Anti- T Lymphocyte Globulin (ATLG) to Assess Impact on Chronic Graft-Versus-Host Disease (cGVHD) Free Survival in Patients Undergoing HLA Matched Unrelated Myeloablative Hematopoietic Cell Transplantation (HCT).” In Blood, 128:505–505. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.505.505.
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  - Stephens, Sarah J., Samantha Thomas, David A. Rizzieri, Mitchell E. Horwitz, Nelson J. Chao, Ashley M. Engemann, Martha Lassiter, and Chris R. Kelsey. “Myeloablative conditioning with total body irradiation for AML: Balancing survival and pulmonary toxicity.” In Adv Radiat Oncol, 1:272–80, 2016. https://doi.org/10.1016/j.adro.2016.07.001.
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  - Huang, Li-Wen, Wendi Bacon, Constance Cirrincione, Bercedis Peterson, Gwynn D. Long, David A. Rizzieri, Mitchell E. Horwitz, et al. “Efficacy of Autologous Stem Cell Transplantation in Older Multiple Myeloma Patients.” In Biology of Blood and Marrow Transplantation, 22:S223–S223. Elsevier BV, 2016. https://doi.org/10.1016/j.bbmt.2015.11.626.
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  - Chen, Yi-Bin, Jennifer Le-Rademacher, Deidre Marie Kiefer, Mehdi Hamadani, John F. DiPersio, Mark R. Litzow, Michael Craig, et al. “A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells in Recipients with Hematological Malignancies.” In Blood, Vol. 126. AMER SOC HEMATOLOGY, 2015.
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  - Scott, Bart L., Marcelo C. Pasquini, Brent Logan, Juan Wu, Steve Devine, David L. Porter, Richard T. Maziarz, et al. “Results of a Phase III Randomized, Multi-Center Study of Allogeneic Stem Cell Transplantation after High Versus Reduced Intensity Conditioning in Patients with Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML): Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0901.” In Blood, Vol. 126. American Society of Hematology, 2015. https://doi.org/10.1182/blood.v126.23.lba-8.lba-8.
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  - Green, Michael M. B., Mitchell E. Horwitz, Yubin Kang, Nelson J. Chao, Gwynn D. Long, David Rizzieri, Cristina Gasparetto, et al. “Administration of Plerixafor (a CXCR4 antagonist) Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation Enhances Platelet Recovery in a Phase I/II Trial.” In Biology of Blood and Marrow Transplantation, 21:S31–32. Elsevier BV, 2015. https://doi.org/10.1016/j.bbmt.2014.11.024.
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  - Pasquini, Marcelo C., Jennifer Le Rademacher, Christopher Flowers, Michael Lill, Luciano J. Costa, Tsiporah B. Shore, William Vaughan, et al. “Matched Pair Comparison of Busulfan/Cyclophosphamide/Etoposide (BuCyE) to Carmustine/Etoposide/Cytarabine/Melphalan (BEAM) Conditioning Regimen Prior to Autologous Hematopoietic Cell Transplantation (autoHCT) for Lymphoma.” In Biology of Blood and Marrow Transplantation, 20:S162–S162. Elsevier BV, 2014. https://doi.org/10.1016/j.bbmt.2013.12.259.
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  - Horwitz, Mitchell E., Patrick J. Stiff, Nelson J. Chao, David Rizzieri, Gwynn Long, Keith Sullivan, Cristina Gasparetto, et al. “Nicord® Expanded Hematopoietic Progenitor Cells (HPC) Are Capable of Outcompeting the Unmanipulated (UM) Cord Blood Unit and of Prolonged Myeloid and Lymphoid Engraftment Following Myeloablative Dual Umbilical Cord Blood (UCB) Transplantation.” In Biology of Blood and Marrow Transplantation, 19:S118–S118. Elsevier BV, 2013. https://doi.org/10.1016/j.bbmt.2012.11.044.
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  - Sung, Anthony D., Julia A. M. Sung, Kelly Corbet, Vera Hars, Lan Lan, Gloria Broadwater, Ashley Zanter, et al. “Surgical Mask Usage Reduces the Incidence of Parainfleunza Virus 3 in Recipients of Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, 19:S271–72. Elsevier BV, 2013. https://doi.org/10.1016/j.bbmt.2012.11.375.
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  - Sung, Anthony D., Julia A. M. Sung, Kelly Corbet, Gloria Broadwater, Vera Hars, Ashley Zanter, Nelson J. Chao, and Mitchell E. Horwitz. “Surgical Mask Usage Reduces the Incidence of Parainfluenza Virus 3 in Recipients of Stem Cell Transplantation.” In Blood, 120:462–462. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.462.462.
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  - Sung, Anthony D., Julia A. M. Sung, Kelly Corbet, Gloria Broadwater, Vera Hars, Ashley Zanter, Nelson J. Chao, and Mitchell E. Horwitz. “Surgical Mask Usage Reduces the Incidence of Parainfluenza Virus 3 in Recipients of Stem Cell Transplantation.” In Blood, Vol. 120. AMER SOC HEMATOLOGY, 2012.
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  - Kanda, J., L. Kaynar, Y. Kanda, V. K. Prasad, S. H. Parikh, D. A. Rizzieri, G. D. Long, et al. “Use of Cyclosporine Is Associated with the Increase in Pre-Engraftment Syndrome After Myeloablative Dual Cord Blood Transplantation.” In Biology of Blood and Marrow Transplantation, 18:S332–S332. Elsevier BV, 2012. https://doi.org/10.1016/j.bbmt.2011.12.336.
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  - Lill, M., S. Lim, R. F. Yeh, E. Waller, L. J. Costa, T. Shore, M. Craig, et al. “Dose Precision Using a Pretransplant Test PK of Intravenous Busulfan Prior to BuCyVP-16 Preparative Regimen in Lymphoma.” In Biology of Blood and Marrow Transplantation, 18:S246–S246. Elsevier BV, 2012. https://doi.org/10.1016/j.bbmt.2011.12.126.
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  - Bacon, Wendi A., Gwynn D. Long, David A. Rizzieri, Mitchell E. Horwitz, John P. Chute, Keith M. Sullivan, Amanda Yopp, Angela Johns, Nelson J. Chao, and Cristina Gasparetto. “Impact of High Dose Cyclophosphamide on the Outcome of Autologous Stem Cell Transplant in Patients with Newly Diagnosed Multiple Myeloma.” In Blood, 118:1765–1765. AMER SOC HEMATOLOGY, 2011.
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  - Chao, Nelson J., Daniel T. Grima, George Carrum, Leona Holmberg, Henry C. Fung, Stephen Brown, Mitchell E. Horwitz, et al. “Chemo-Mobilization Provides Superior Mobilization and Collection in Autologous Stem Cell Transplants but with Less Predictability and At a Higher Cost.” In Blood, 118:1729–1729. AMER SOC HEMATOLOGY, 2011.
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  - Chao, Nelson J., Lisa M. Bernard, George Carrum, Henry C. Fung, Daniel T. Grima, Leona Holmberg, Stephen Brown, et al. “Differences in Stem Cell Collection Practices and Related Outcomes Between Centers That Conduct and Do Not Conduct Aphaeresis on Weekends.” In Blood, 118:839–40. AMER SOC HEMATOLOGY, 2011.
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  - Gasparetto, Cristina, Wendi A. Bacon, Phuong Doan, David A. Rizzieri, Mitchell E. Horwitz, John P. Chute, Keith M. Sullivan, et al. “High Dose BCNU/Melphalan Preparative Regimen Doubles Event Free Survival of Myeloma Patients Undergoing Autologous Transplantation.” In Blood, 118:879–879. AMER SOC HEMATOLOGY, 2011.
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  - Kanda, Junya, David A. Rizzieri, Gwynn D. Long, Cristina Gasparetto, John P. Chute, Keith M. Sullivan, Ashley Morris, et al. “The Impact of Lymphocyte Subset Recovery At 3 Months on Progression-Free Survival After Myeloablative Allogeneic Stem Cell Transplantation.” In Blood, 118:1736–1736. AMER SOC HEMATOLOGY, 2011.
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  - Kanda, J., M. E. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. P. Chute, A. Morris, T. Hennig, N. J. Chao, and D. A. Rizzieri. “Outcomes of a 1-Day Nonmyeloablative Preparative Regimen for Primary Graft Failure After Allogeneic Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, 17:S308–S308. Elsevier BV, 2011. https://doi.org/10.1016/j.bbmt.2010.12.460.
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  - Biernacki, Melinda A., Maureen Okam, Shalini Shenoy, Lakshmanan Krishnamurti, Mitchell E. Horwitz, Donna Neuberg, Joseph H. Antin, and Catherine J. Wu. “Long-Term Follow-up of Adults with Severe Sickle Cell Disease After Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning.” In Blood, 116:120–120. AMER SOC HEMATOLOGY, 2010.
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  - Chiou, Lun-Wei, Junya Kanda, Paul Szabolcs, Gregory E. Sempowski, Jeffrey Hale, Donna Niedzwiecki, Gloria Broadwater, Nelson J. Chao, and Mitchell E. Horwitz. “A Comprehensive Comparison Immune Recovery In Adult Patients Following Allogeneic Umbilical Cord Blood, Matched Sibling and Matched Unrelated Donor Stem Cell Transplantation.” In Blood, 116:954–55. AMER SOC HEMATOLOGY, 2010.
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  - Horwitz, Mitchell E., Edward Gorak, Peter Holman, Edward Libby, Dirk Huebner, Purvi D. Mody, and Jeffrey R. Schriber. “Efficacy and Safety of Hematopoietic Stem Cell Remobilization with Plerixafor (Mozobil (R)) plus G-CSF In Adult Patients with Non-Hematologic Malignancies.” In Blood, 116:925–925. AMER SOC HEMATOLOGY, 2010.
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  - Hutchinson, Charles Blake, Jennifer H. Crow, Huang Qin, Chuanyi M. Lu, Siby Sebastain, Catherine Rehder, Anand S. Lagoo, et al. “Donor Cell Leukemia: A Clinicopathological Study of 9 Cases and a Comprehensive Review of Literature.” In Blood, 116:1423–24. AMER SOC HEMATOLOGY, 2010.
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  - Kanda, Junya, Gwynn D. Long, Cristina Gasparetto, Mitchell E. Horwitz, Keith M. Sullivan, John P. Chute, Ashley Morris, Zhiguo Li, Nelson J. Chao, and David A. Rizzieri. “Prospective, Biological Randomized Study of T-Cell Depleted Nonmyeloablative Allogeneic Transplantation From HLA-Matched Related, Unrelated or Haploidentical Donors for Patients with Hematologic Malignancies.” In Blood, 116:1456–57. AMER SOC HEMATOLOGY, 2010.
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  - Khan, T., K. Richard, G. Broadwater, S. E. Hemphill, M. Lassiter, and M. E. Horwitz. “Polyoma Virus Is The Principal Cause Of Cystitis Following Alemtuzumab-Based Allogeneic Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, 16:S319–S319. Elsevier BV, 2010. https://doi.org/10.1016/j.bbmt.2009.12.487.
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  - Page, K. M., T. Gentry, K. Shoulars, M. E. Horwitz, N. Herrmann, N. Meadows, B. Philipps, A. Balber, and J. Kurtzberg. “Aldehyde Dehydrogenase Cell Dosing Predicts The Dominating Cord In Double Cord Blood Transplantation.” In Biology of Blood and Marrow Transplantation, 16:S267–68. Elsevier BV, 2010. https://doi.org/10.1016/j.bbmt.2009.12.340.
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  - Gasparetto, Cristina, Mitchell E. Horwitz, Jon P. Gockerman, Carlos M. de Castro, Joseph O. Moore, Clay A. Smith, Patty Davis, et al. “Campath-1H May Have Activity in the Treatment of Multiple Myeloma.” In Blood, 104:4931–4931. American Society of Hematology, 2004. https://doi.org/10.1182/blood.v104.11.4931.4931.
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  - Ryser, M. F., S. Brenner, N. Whiting-Theobald, R. Lehmann, U. Choi, G. F. Linton, E. Kang, et al. “Insertional analyses in rhesus monkey blood cells after non-myeloablative hematopoietic stem cell marking with a therapeutic onco-retroviral vector for X-linked chronic granulomatous disease.” In Molecular Therapy, 9:S350–S350. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004.
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  - Gasparetto, C., N. J. Chao, M. E. Horwitz, J. O. Moore, C. DeCastro, J. Gockerman, K. Sullivan, et al. “Pharmacokinetics of subcutaneous alemtuzumab in a patient with myeloma.” In Blood, 102:385B-385B. AMER SOC HEMATOLOGY, 2003.
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  - Goggins, T. F., D. A. Rizzieri, R. Prosnitz, C. Gasparetto, G. Long, M. E. Horwitz, K. Sullivan, et al. “One day preparative regimen for allogeneic non-myeloablative stem cell transplantation (NMSCT) using 3-5/6 HLA matched related donors.” In Blood, 102:476B-477B. AMER SOC HEMATOLOGY, 2003.
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  - Rizzieri, D. A., L. P. Koh, G. D. Long, A. S. Lagoo, C. Gasparatto, J. J. Vredenburgh, P. J. Buckley, et al. “Clinical outcome and immune reconstitution following alemtuzumab T cell depleted nonmyeloablative allogeneic immunotherapy from HLA matched siblings.” In Blood, 102:238A-239A. AMER SOC HEMATOLOGY, 2003.
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