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Matthew Leonard Maciejewski

Professor in Population Health Sciences
Population Health Sciences
Duke Box 2720, Durham, NC 27705
215 Morris Street (Imperial), Suite 210, Durham, NC 27701

Overview


Matt Maciejewski, PhD is a Professor in the Department of Population Health Sciences. He is also a Senior Research Career Scientist in the Center of Innovation to Accelerate Discovery and Practice Transformation at the Durham VA Medical Center. Matt also holds Adjunct Professor appointments in the Schools of Public Health and Pharmacy at the University of North Carolina at Chapel Hill.

He has received funding from NIDDK, NIDA, CMS, AHRQ, FDA, VA HSR&D, and the RWJ Foundation to conduct evaluation of long-term clinical and economic outcomes of surgical interventions, behavioral interventions and Medicare program/policy changes on patients with obesity or cardiometabolic conditions.  He is also interested in methods for addressing unobserved confounding in observational studies.  Matt evaluated the first-ever population-based implementation of value-based insurance design and led the first-ever linkage of lab results and Medicare FFS claims.  He has published over 325 papers in peer-reviewed journals such as JAMA, JAMA Internal Medicine, JAMA Surgery, Annals of Internal Medicine, Health Economics, Medical Care, and Health Services Research.

Areas of expertise: Health Services Research, Health Economics, Health Policy, Multimorbidity, treatments for obesity

Current Duke Appointments & Affiliations


Professor in Population Health Sciences · 2021 - Present Population Health Sciences, Basic Science Departments
Professor in Medicine · 2020 - Present Medicine, General Internal Medicine, Medicine
Core Faculty Member, Duke-Margolis Institute for Health Policy · 2024 - Present Duke-Margolis Institute for Health Policy, University Institutes and Centers

Recent News Items


Published January 29, 2025
Bariatric Surgery Shown to Reduce Health Costs
Published September 6, 2016
Bariatric Surgery Can Help People Keep Weight Off Long Term
Published September 1, 2016
Do the benefits of weight-loss surgery really last?

View All News Items

Recent Scholarly Works


Implementing Advanced Comprehensive Diabetes Care Within the Veterans Affairs Learning Health System.

Journal article J Gen Intern Med · October 2026 BACKGROUND: Telehealth can improve glycemic control for patients with type 2 diabetes (T2D), but programs must be designed in a manner that facilitates real-world uptake and effectiveness within learning health systems (LHS). OBJECTIVE: To highlight how th ... Full text Link to item Cite

"It Would be a Burden off My Back": Veterans' Perceptions of Social Risk and Needs Screening Acceptability.

Journal article J Gen Intern Med · September 23, 2026 BACKGROUND: Many health systems seek to identify social risks (individual-level social and economic conditions such as food insecurity, financial strain) and address needs. However, the impact of these efforts relies in part on patient acceptability of scr ... Full text Link to item Cite

Methodological Approaches to Real-World Evidence Generation for Glucagon-like Peptide-1-Based Therapies: Synopsis of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

Journal article Ann Intern Med · September 2026 Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have reshaped the clinical approach to managing obesity and type 2 diabetes. As approved indications have expanded, use of GLP-1RAs has increased rapidly in the United States. Although randomized trials ... Full text Link to item Cite
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Recent Grants


2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Center for Advancing Translational Sciences · 2025 - 2030

Deprescribing Decision-Making using Machine Learning Individualized Treatment Rules to Improve CNS Polypharmacy

ResearchCo Investigator · Awarded by National Institute on Aging · 2024 - 2029

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Education


University of Minnesota, Twin Cities · 1998 Ph.D.

External Links


Google Scholar