Overview
Matt Maciejewski, PhD is a Professor in the Department of Population Health Sciences. He is also a Senior Research Career Scientist in the Center of Innovation to Accelerate Discovery and Practice Transformation at the Durham VA Medical Center. Matt also holds Adjunct Professor appointments in the Schools of Public Health and Pharmacy at the University of North Carolina at Chapel Hill.
He has received funding from NIDDK, NIDA, CMS, AHRQ, FDA, VA HSR&D, and the RWJ Foundation to conduct evaluation of long-term clinical and economic outcomes of surgical interventions, behavioral interventions and Medicare program/policy changes on patients with obesity or cardiometabolic conditions. He is also interested in methods for addressing unobserved confounding in observational studies. Matt evaluated the first-ever population-based implementation of value-based insurance design and led the first-ever linkage of lab results and Medicare FFS claims. He has published over 325 papers in peer-reviewed journals such as JAMA, JAMA Internal Medicine, JAMA Surgery, Annals of Internal Medicine, Health Economics, Medical Care, and Health Services Research.
Areas of expertise: Health Services Research, Health Economics, Health Policy, Multimorbidity, treatments for obesity
He has received funding from NIDDK, NIDA, CMS, AHRQ, FDA, VA HSR&D, and the RWJ Foundation to conduct evaluation of long-term clinical and economic outcomes of surgical interventions, behavioral interventions and Medicare program/policy changes on patients with obesity or cardiometabolic conditions. He is also interested in methods for addressing unobserved confounding in observational studies. Matt evaluated the first-ever population-based implementation of value-based insurance design and led the first-ever linkage of lab results and Medicare FFS claims. He has published over 325 papers in peer-reviewed journals such as JAMA, JAMA Internal Medicine, JAMA Surgery, Annals of Internal Medicine, Health Economics, Medical Care, and Health Services Research.
Areas of expertise: Health Services Research, Health Economics, Health Policy, Multimorbidity, treatments for obesity
Current Appointments & Affiliations
Professor in Population Health Sciences
·
2021 - Present
Population Health Sciences,
Basic Science Departments
Professor in Medicine
·
2020 - Present
Medicine, General Internal Medicine,
Medicine
Core Faculty Member, Duke-Margolis Institute for Health Policy
·
2024 - Present
Duke-Margolis Institute for Health Policy,
University Institutes and Centers
Recent Publications
Implementing Advanced Comprehensive Diabetes Care Within the Veterans Affairs Learning Health System.
Journal Article J Gen Intern Med · November 4, 2025 BACKGROUND: Telehealth can improve glycemic control for patients with type 2 diabetes (T2D), but programs must be designed in a manner that facilitates real-world uptake and effectiveness within learning health systems (LHS). OBJECTIVE: To highlight how th ... Full text Link to item CiteImpact of time zero designation on estimated COVID-19 antiviral effectiveness in observational studies.
Journal Article Am J Epidemiol · October 13, 2025 In a well-designed clinical trial, time zero is when eligibility is determined, treatment is assigned, follow-up time begins, and each of these elements is aligned. Attaining this alignment can be challenging in observational studies, risking potential bia ... Full text Link to item CiteA partner-informed approach to prioritizing social risks for research in a learning health system.
Journal Article Learn Health Syst · October 2025 OBJECTIVE: To prioritize social risks (individual-level social and economic conditions) that may influence a person's health for inclusion in a national survey of Veterans Affairs (VA) healthcare system patients. DATA SOURCES AND STUDY SETTING: Quantitativ ... Full text Link to item CiteRecent Grants
2/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030Deprescribing Decision-Making using Machine Learning Individualized Treatment Rules to Improve CNS Polypharmacy
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2029Duke KURe Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2013 - 2028View All Grants
Education, Training & Certifications
University of Minnesota, Twin Cities ·
1998
Ph.D.