Overview
I am Dr. Mona Marie, a dedicated researcher with a strong background in pharmaceutical sciences and biotechnology. Having earned my Ph.D. in Biomedical Sciences from the Brody School of Medicine at East Carolina University, I have a robust foundation in exploring the intricate roles of G protein-coupled receptors (GPCRs) in inflammation and cancer.
Background:
My journey in research began during my master's studies in Egypt, where I investigated the Effect of Cannabidiol on breast cancer progression. This early exposure to the complexities of molecular interactions fueled my passion for understanding the pharmacology of receptors.
Current Focus:
Building on my previous work, my current research, conducted in both in vivo and in vitro settings, centers around the roles of Olfactory receptors, another intriguing family of GPCRs. I am fascinated by their diverse functions, not only within the olfactory system but also in extra-nasal tissues.
Proposed Research:
Looking ahead, my research agenda aims to delve deeper into the pharmacology of olfactory receptors. I plan to unravel the specific molecular basis of olfactory receptor function and its direct translation to downstream molecular interactions, shedding light on their potential therapeutic applications.
Approach:
Utilizing state-of-the-art techniques such as ligand binding assays, cell signaling studies, and advanced imaging, I will dissect the pharmacological profiles of olfactory receptors. Furthermore, my exploration will focus on understanding the molecular aspects of olfaction by investigating how these receptors can be pharmacologically modulated. This investigation into receptor-ligand interactions not only enhances our comprehension of olfactory processes but also holds the potential to provide insights into the extranasal roles of these receptors, particularly in detecting in vivo ligands."
Significance:
Understanding the pharmacology of olfactory receptors holds promise for novel therapeutic interventions. Whether in the context of sensory perception or extra-nasal functions, deciphering the intricacies of these receptors can open avenues for the development of pharmacological agents with a wide range of applications.
Long-Term Goals:
In the long term, I aspire to establish myself as a leading researcher in the field of receptor pharmacology and translational medicine. My goal is to contribute to the development of targeted therapies based on a comprehensive understanding of receptor function, bridging the gap between basic research and practical applications.
In conclusion, my research endeavors are driven by a commitment to unraveling the pharmacological mysteries of olfactory receptors. By applying cutting-edge techniques and a multidisciplinary approach, I aim to contribute valuable insights to the broader field of pharmacology and lay the groundwork for potential therapeutic advancements.