David Charles Montefiori
Professor in Surgery
Dr. Montefiori is Professor and Director of the Laboratory for AIDS Vaccine Research and Development in the Department of Surgery, Division of Surgical Sciences, Duke University Medical Center. His major research interests are viral immunology and AIDS vaccine development, with a special emphasis on neutralizing antibodies. One of his highest priorities is to identify immunogens that generate broadly cross-reactive neutralizing antibodies for inclusion in HIV vaccines. Many aspects of the neutralizing antibody response are studied in his laboratory, including mechanisms of neutralization and escape, epitope diversity among genetic subtypes and geographic origins, ontogeny of broadly neutralizing antibody responses and computationally-assisted vaccine design. Over the years he has explored multiple types of assays for neutralizing antibodies and other potential antiviral antibodies, focusing on assay optimization, standardization, validation and high throughput. The scope of research covers HIV-infected individuals and nonhuman primate models of simian immunodeficiency virus (SIV) and simian-human immunodeficiency virus (SHIV) infection. Dr. Montefiori also directs a large AIDS vaccine immune monitoring program, which operates in compliance with Good Clinical Laboratory Practice and has served as a national and international resource for standardized assessments of neutralizing antibody responses in preclinical and clinical trials of candidate AIDS vaccines since 1988. In 2002 he chaired the Antibody Laboratory Standardization Working Group that assisted in the design of the Global HIV Vaccine Enterprise Strategic Plan for HIV vaccines. He currently directs the Core Neutralizing Antibody Laboratories for the HIV Vaccine Clinical Trials Network (HVTN), the NIH Preclinical HIV-1 Vaccine Program and the Center for HIV/AIDS Vaccine Immunology- Immunogen Design (CHAVI-ID). He also directs a large Comprehensive Antibody Vaccine Immune Monitoring Consortium (CAVIMC) as part of the Bill and Melinda Gates Foundation's Collaboration for AIDS Vaccine Discovery (CAVD). He has published over 500 original research papers that have helped shape the scientific rationale for antibody-based HIV-1 vaccines.
Current Appointments & Affiliations
- Professor in Surgery, Surgery, Surgical Sciences, Surgery 2021
- Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2006
Contact Information
- Box 2926 Med Ctr, Durham, NC 27710
- Surgical Oncology Res Fac, Durham, NC 27710
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monte@duke.edu
(919) 684-5278
- Background
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Education, Training, & Certifications
- Ph.D., Clemson University 1982
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Previous Appointments & Affiliations
- Professor of Surgery, Surgery, Surgical Sciences, Surgery 2013 - 2020
- Professor of Surgery, Surgery, Surgical Sciences, Surgery 2006 - 2013
- Research Professor in Surgery, Surgery, Surgical Sciences, Surgery 2000 - 2006
- Associate Research Professor in Surgery, Surgery, Surgical Sciences, Surgery 1996 - 2000
- Associate Research Professor of Experimental Surgery in the Department of Surgery, Surgery, Clinical Science Departments 1994 - 1996
- Recognition
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In the News
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DEC 13, 2022 -
JAN 28, 2022 Duke Health News -
DEC 3, 2021 -
APR 8, 2021 Duke Health News -
NOV 19, 2019 -
NOV 27, 2018 -
APR 29, 2016 The Scientist -
APR 29, 2016 The Scientist
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- Research
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Selected Grants
- CAVIMC 2022-2026 Grant Renewal awarded by Bill and Melinda Gates Foundation 2016 - 2026
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2025
- CIVICS A - Option 21A Equitable Adjustment awarded by National Institutes of Health 2022 - 2025
- CIVICS A - Option 21A awarded by National Institute of Allergy and Infectious Diseases 2021 - 2025
- CISA COVID Flu Immunogenicity awarded by Centers for Disease Control and Prevention 2022 - 2024
- CISA COVID Peds Immunogenicity awarded by Centers for Disease Control and Prevention 2022 - 2024
- CISA Maternal COVID Immunogenicity awarded by Centers for Disease Control and Prevention 2022 - 2024
- Moderna mRNA1275 P205 Trial Neutralizing Antibody Assessment awarded by Moderna Therapeutics, Inc. 2021 - 2024
- A Phase 2/3, Two-Part, Open-Label, Dose-Escalation, Age De-escalation and Randomized, Observer-Blind, Placebo-Controlled, Expansion Study to Evaluate the Safety, Tolerability, Reactogenicity, and Effe awarded by Moderna Therapeutics, Inc. 2021 - 2024
- EQAPOL SARS CoV-2 Option 45 awarded by National Institutes of Health 2022 - 2023
- CIVICs A - Option 18C awarded by National Institutes of Health 2022 - 2023
- A Phase 1, Randomized, Observer-Blind, Dose-Ranging Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 and mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18-55 Years awarded by Moderna Therapeutics, Inc. 2021 - 2023
- Moderna mRNA-1273 P201 (Part B) Trial Neutralizing Antibody Assessment awarded by Moderna Therapeutics, Inc. 2021 - 2023
- Duke CTSA (TL1) Year 5 awarded by National Institutes of Health 2018 - 2023
- CIVICs A - Option 18B SAVE Aim 3 awarded by National Institute of Allergy and Infectious Diseases 2021 - 2023
- A Phase 3b, Open-Label, Safety and Immunogenicity Study of SARS-CoV-2 mRNA-1273 Vaccine in Adult Solid Organ Transplant Recipients and Healthy Controls awarded by Moderna Therapeutics, Inc. 2021 - 2023
- Neutralizing Antibody Response Assessment for a Phase 2/3 Randomized, Observer-Blind, Placebo-Controlled, Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 SARS-CoV-2 Vaccin awarded by Moderna Therapeutics, Inc. 2021 - 2023
- Nonhuman Primate Option 4 awarded by National Institutes of Health 2018 - 2023
- CoVPN 3001 A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine awarded by Fred Hutchinson Cancer Center 2022
- CoVPN 3008 Multi-Center, Randomized, Efficacy Study of Early vs Deferred Vaccination with COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern awarded by Fred Hutchinson Cancer Center 2022
- CoVPN 5001 A Prospective Study of Acute Immune Responses to SARS-CoV-2 Infection awarded by Fred Hutchinson Cancer Center 2022
- HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals awarded by Fred Hutchinson Cancer Center 2022
- HVTN LC awarded by Fred Hutchinson Cancer Center 2022
- HVTN Laboratory Center: Phase 1 PF awarded by Fred Hutchinson Cancer Center 2022
- EQAPOL SARS CoV-2 Option 44 awarded by National Institutes of Health 2021 - 2022
- A PHASE 2a, RANDOMIZED, OBSERVER-BLIND, PLACEBO-CONTROLLED, DOSE-CONFIRMATION STUDY TO EVALUATE THE SAFETY, REACTOGENICITY, AND IMMUNOGENICITY OF MRNA-1273 SARS-COV-2 VACCINE IN ADULTS AGED 18 YEARS A awarded by Moderna Therapeutics, Inc. 2021 - 2022
- Neutralizing antibody assessment for EID 030 SARS-CoV-2 Vaccine Phase I trial awarded by Henry M. Jackson Foundation 2021 - 2022
- CIVICs A - Option 18A SAVE Aims 1, 2 awarded by National Institute of Allergy and Infectious Diseases 2021 - 2022
- CoVPN 3008 Multi-Center, Randomized, Efficacy Study of Early vs Deferred Vaccination with COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern awarded by Fred Hutchinson Cancer Research Center 2020 - 2022
- HVTN Laboratory Center: Phase 1 PF awarded by Fred Hutchinson Cancer Research Center 2020 - 2022
- CoVPN 5001 A prospective study of acute immune responses to SARS-CoV2 infection - LAB awarded by Fred Hutchinson Cancer Research Center 2020 - 2022
- HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals awarded by Fred Hutchinson Cancer Research Center 2020 - 2022
- EQAPOL SARS CoV-2 EQA Option 43 awarded by National Institutes of Health 2021
- EQAPOL SARS CoV-2 EQA Option 42 awarded by National Institutes of Health 2020 - 2021
- NIAID Virology Quality Assurance - Options 27 Only awarded by National Institutes of Health 2020 - 2021
- Role of neutralizing antibodies in HIV-1-infected and vaccinated mothers in MTCT awarded by National Institutes of Health 2016 - 2021
- Primate Contract Expansion for Covid-19 awarded by National Institutes of Health 2020 - 2021
- Protocol Development Assays awarded by Fred Hutchinson Cancer Research Center 2019 - 2020
- HVTN Laboratory Center: HVTN 704 awarded by Fred Hutchinson Cancer Research Center 2015 - 2020
- HVTN Laboratory Center: HVTN Phase 1 awarded by Fred Hutchinson Cancer Research Center 2015 - 2020
- HVTN Laboratory Center: HVTN 117 awarded by Fred Hutchinson Cancer Research Center 2017 - 2018
- HVTN Laboratory Center: HVTN 118 awarded by Fred Hutchinson Cancer Research Center 2017 - 2018
- RAMP Scholar Award Shay Behrens awarded by Fred Hutchinson Cancer Research Center 2016 - 2018
- HIV Vaccine Trials Network: LC P5 PF awarded by Fred Hutchinson Cancer Research Center 2015 - 2018
- Nonhuman Primate Core-Option 6 awarded by National Institutes of Health 2012 - 2018
- Option 13 Non Human Primate Core awarded by National Institutes of Health 2012 - 2018
- Option 19 Non Human Primate Core awarded by National Institutes of Health 2012 - 2017
- HIV Vaccine Trials Network: LC P5 PF awarded by Fred Hutchinson Cancer Research Center 2014 - 2015
- LC: HIV Vaccine Trials Network: Phase 1 PF awarded by Fred Hutchinson Cancer Research Center 2014 - 2015
- HIV Envelope-specific functional antibody responses in HIV-exposed, HIV-vaccinated infants awarded by National Institutes of Health 2012 - 2015
- Methods to Determine HIV Transport and Inactivation by Microbicide Coating Layers awarded by National Institutes of Health 2009 - 2012
- Nonhuman Primate Core Humoral Immunology Laboratory for AIDS Vaccine Research and Development awarded by National Institutes of Health 2011 - 2012
- Central Laboratory for the HIV Vaccines Trial Network awarded by National Institutes of Health 2000 - 2006
- A Universal Env Immunogen for all HIV-1 Subtypes awarded by National Institutes of Health 2003 - 2006
- Same awarded by National Institutes of Health 1997 - 2002
- Host Virus Interactions During Acute Infection awarded by National Institutes of Health 1996 - 1999
- Perform Neutralizing Assays On Hiv,Siv,And Shiv, And Adopt awarded by National Institutes of Health 1993 - 1998
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Pahar, Bapi, Wayne Gray, Marissa Fahlberg, Brooke Grasperge, Meredith Hunter, Arpita Das, Christopher Mabee, et al. “Recombinant Simian Varicella Virus-Simian Immunodeficiency Virus Vaccine Induces T and B Cell Functions and Provides Partial Protection against Repeated Mucosal SIV Challenges in Rhesus Macaques.” Viruses 14, no. 12 (December 17, 2022). https://doi.org/10.3390/v14122819.Full Text Link to Item
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Chalkias, Spyros, Jing Feng, Xing Chen, Honghong Zhou, Jean-Claude Marshall, Bethany Girard, Joanne E. Tomassini, Barbara J. Kuter, David C. Montefiori, and Rituparna Das. “Neutralization of Omicron Subvariant BA.2.75 after Bivalent Vaccination.” N Engl J Med 387, no. 23 (December 8, 2022): 2194–96. https://doi.org/10.1056/NEJMc2212772.Full Text Link to Item
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Leggat, David J., Kristen W. Cohen, Jordan R. Willis, William J. Fulp, Allan C. deCamp, Oleksandr Kalyuzhniy, Christopher A. Cottrell, et al. “Vaccination induces HIV broadly neutralizing antibody precursors in humans.” Science 378, no. 6623 (December 2, 2022): eadd6502. https://doi.org/10.1126/science.add6502.Full Text Link to Item
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Huang, Yunda, Lily Zhang, Amanda Eaton, Nonhlanhla N. Mkhize, Lindsay N. Carpp, Erika Rudnicki, Allan DeCamp, et al. “Prediction of serum HIV-1 neutralization titers of VRC01 in HIV-uninfected Antibody Mediated Prevention (AMP) trial participants.” Human Vaccines & Immunotherapeutics 18, no. 1 (December 2022): 1908030. https://doi.org/10.1080/21645515.2021.1908030.Full Text
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Reiss, E. I. M. M., M. M. van Haaren, J. van Schooten, M. A. F. Claireaux, P. Maisonnasse, A. Antanasijevic, J. D. Allen, et al. “Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates.” Npj Vaccines 7, no. 1 (November 25, 2022): 152. https://doi.org/10.1038/s41541-022-00576-9.Full Text Link to Item
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Knudsen, Maria L., Parul Agrawal, Anna MacCamy, K Rachael Parks, Matthew D. Gray, Brittany N. Takushi, Arineh Khechaduri, et al. “Adjuvants influence the maturation of VRC01-like antibodies during immunization.” Iscience 25, no. 11 (November 18, 2022): 105473. https://doi.org/10.1016/j.isci.2022.105473.Full Text Link to Item
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El Sahly, Hana M., Lindsey R. Baden, Brandon Essink, David Montefiori, Adrian McDermont, Richard Rupp, Michael Lewis, et al. “Humoral Immunogenicity of the mRNA-1273 Vaccine in the Phase 3 Coronavirus Efficacy (COVE) Trial.” J Infect Dis 226, no. 10 (November 11, 2022): 1731–42. https://doi.org/10.1093/infdis/jiac188.Full Text Link to Item
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Chalkias, Spyros, Frank Eder, Brandon Essink, Shishir Khetan, Biliana Nestorova, Jing Feng, Xing Chen, et al. “Safety, immunogenicity and antibody persistence of a bivalent Beta-containing booster vaccine against COVID-19: a phase 2/3 trial.” Nat Med 28, no. 11 (November 2022): 2388–97. https://doi.org/10.1038/s41591-022-02031-7.Full Text Link to Item
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Schooten, Jelle van, Anna Schorcht, Elinaz Farokhi, Jeffrey C. Umotoy, Hongmei Gao, Tom L. G. M. van den Kerkhof, Jessica Dorning, et al. “Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.” Plos Pathog 18, no. 11 (November 2022): e1010945. https://doi.org/10.1371/journal.ppat.1010945.Full Text Link to Item
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Luo, Sai, Jun Zhang, Alex J. B. Kreutzberger, Amanda Eaton, Robert J. Edwards, Changbin Jing, Hai-Qiang Dai, et al. “An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.” Sci Immunol 7, no. 76 (October 28, 2022): eadd5446. https://doi.org/10.1126/sciimmunol.add5446.Full Text Link to Item
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Moy, James N., Mark Anderson, Xiaoying Shen, Jia Fu, Michael Stec, Amy Gosha, Dina Naquiallah, et al. “Neutralizing Antibody Activity to Severe Acute Respiratory Syndrome Coronavirus 2 Delta (B.1.617.2) and Omicron (B.1.1.529) After 1 or 2 Doses of BNT162b2 Vaccine in Infection-Naive and Previously Infected Individuals.” J Infect Dis 226, no. 8 (October 17, 2022): 1407–11. https://doi.org/10.1093/infdis/jiac261.Full Text Link to Item
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Chalkias, Spyros, Charles Harper, Keith Vrbicky, Stephen R. Walsh, Brandon Essink, Adam Brosz, Nichole McGhee, et al. “A Bivalent Omicron-Containing Booster Vaccine against Covid-19.” N Engl J Med 387, no. 14 (October 6, 2022): 1279–91. https://doi.org/10.1056/NEJMoa2208343.Full Text Link to Item
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Li, Dapeng, David R. Martinez, Alexandra Schäfer, Haiyan Chen, Maggie Barr, Laura L. Sutherland, Esther Lee, et al. “Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine.” Nature Communications 13, no. 1 (October 2022): 6309. https://doi.org/10.1038/s41467-022-33985-4.Full Text Open Access Copy
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Shen, Xiaoying, Spyros Chalkias, Jing Feng, Xing Chen, Honghong Zhou, Jean-Claude Marshall, Bethany Girard, et al. “Neutralization of SARS-CoV-2 Omicron BA.2.75 after mRNA-1273 Vaccination.” N Engl J Med 387, no. 13 (September 29, 2022): 1234–36. https://doi.org/10.1056/NEJMc2210648.Full Text Link to Item
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Saunders, Kevin O., Robert J. Edwards, Kedamawit Tilahun, Kartik Manne, Xiaozhi Lu, Derek W. Cain, Kevin Wiehe, et al. “Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.” Sci Transl Med 14, no. 661 (September 7, 2022): eabo5598. https://doi.org/10.1126/scitranslmed.abo5598.Full Text Link to Item
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Gilbert, Peter B., Yunda Huang, Allan C. deCamp, Shelly Karuna, Yuanyuan Zhang, Craig A. Magaret, Elena E. Giorgi, et al. “Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition.” Nat Med 28, no. 9 (September 2022): 1924–32. https://doi.org/10.1038/s41591-022-01953-6.Full Text Link to Item
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Lee, Jeong Hyun, Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall, Rebecca Nedellec, et al. “Long-primed germinal centres with enduring affinity maturation and clonal migration.” Nature 609, no. 7929 (September 2022): 998–1004. https://doi.org/10.1038/s41586-022-05216-9.Full Text Link to Item
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Schooten, Jelle van, Elinaz Farokhi, Anna Schorcht, Tom L. G. M. van den Kerkhof, Hongmei Gao, Patricia van der Woude, Judith A. Burger, et al. “Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.” Nat Commun 13, no. 1 (August 3, 2022): 4515. https://doi.org/10.1038/s41467-022-32208-0.Full Text Link to Item
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Lyke, Kirsten E., Robert L. Atmar, Clara Dominguez Islas, Christine M. Posavad, Daniel Szydlo, Rahul Paul Chourdhury, Meagan E. Deming, et al. “Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant.” Cell Rep Med 3, no. 7 (July 19, 2022): 100679. https://doi.org/10.1016/j.xcrm.2022.100679.Full Text Link to Item
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Fears, Alyssa C., Brandon J. Beddingfield, Nicole R. Chirichella, Nadia Slisarenko, Stephanie Z. Killeen, Rachel K. Redmann, Kelly Goff, et al. “Exposure modality influences viral kinetics but not respiratory outcome of COVID-19 in multiple nonhuman primate species.” Plos Pathog 18, no. 7 (July 2022): e1010618. https://doi.org/10.1371/journal.ppat.1010618.Full Text Link to Item
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Wee, Edmund G., Nathifa A. Moyo, Kevin O. Saunders, Celia LaBranche, Filippo Donati, Silvia Capucci, Robert Parks, et al. “Erratum: Parallel Induction of CH505 B Cell Ontogeny-Guided Neutralizing Antibodies and tHIVconsvX Conserved Mosaic-Specific T Cells against HIV-1.” Mol Ther Methods Clin Dev 25 (June 9, 2022): 490. https://doi.org/10.1016/j.omtm.2022.05.001.Full Text Link to Item
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Gobeil, Sophie M-C, Rory Henderson, Victoria Stalls, Katarzyna Janowska, Xiao Huang, Aaron May, Micah Speakman, et al. “Structural diversity of the SARS-CoV-2 Omicron spike.” Mol Cell 82, no. 11 (June 2, 2022): 2050-2068.e6. https://doi.org/10.1016/j.molcel.2022.03.028.Full Text Link to Item
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Tu, Joshua J., Amit Kumar, Elena E. Giorgi, Joshua Eudailey, Celia C. LaBranche, David R. Martinez, Genevieve G. Fouda, et al. “Vertical HIV-1 Transmission in the Setting of Maternal Broad and Potent Antibody Responses.” Journal of Virology 96, no. 11 (June 2022): e0023122. https://doi.org/10.1128/jvi.00231-22.Full Text
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Welles, Hugh C., Hannah A. D. King, Leonard Nettey, Nicole Cavett, Jason Gorman, Tongqing Zhou, Yaroslav Tsybovsky, et al. “Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4.” Plos Pathog 18, no. 6 (June 2022): e1010574. https://doi.org/10.1371/journal.ppat.1010574.Full Text Link to Item
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Heydarchi, Behnaz, Danielle S. Fong, Hongmei Gao, Natalia A. Salazar-Quiroz, Jack M. Edwards, Christopher A. Gonelli, Samantha Grimley, et al. “Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody.” Cell Rep Med 3, no. 5 (May 17, 2022): 100635. https://doi.org/10.1016/j.xcrm.2022.100635.Full Text Link to Item
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Lucier, Amanda, Youyi Fong, Shuk Hang Li, Maria Dennis, Joshua Eudailey, Ashley Nelson, Kevin Saunders, et al. “Frequent Development of Broadly Neutralizing Antibodies in Early Life in a Large Cohort of Children With Human Immunodeficiency Virus.” J Infect Dis 225, no. 10 (May 16, 2022): 1731–40. https://doi.org/10.1093/infdis/jiab629.Full Text Link to Item
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Gray, Matthew D., Junli Feng, Connor E. Weidle, Kristen W. Cohen, Lamar Ballweber-Fleming, Anna J. MacCamy, Crystal N. Huynh, et al. “Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain.” Sci Adv 8, no. 18 (May 6, 2022): eabm3948. https://doi.org/10.1126/sciadv.abm3948.Full Text Link to Item
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Chu, Laurence, Keith Vrbicky, David Montefiori, Wenmei Huang, Biliana Nestorova, Ying Chang, Andrea Carfi, et al. “Immune response to SARS-CoV-2 after a booster of mRNA-1273: an open-label phase 2 trial.” Nat Med 28, no. 5 (May 2022): 1042–49. https://doi.org/10.1038/s41591-022-01739-w.Full Text Link to Item
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DeGrace, Marciela M., Elodie Ghedin, Matthew B. Frieman, Florian Krammer, Alba Grifoni, Arghavan Alisoltani, Galit Alter, et al. “Defining the risk of SARS-CoV-2 variants on immune protection.” Nature 605, no. 7911 (May 2022): 640–52. https://doi.org/10.1038/s41586-022-04690-5.Full Text Link to Item
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Atmar, Robert L., Kirsten E. Lyke, Meagan E. Deming, Lisa A. Jackson, Angela R. Branche, Hana M. El Sahly, Christina A. Rostad, et al. “Homologous and Heterologous Covid-19 Booster Vaccinations.” N Engl J Med 386, no. 11 (March 17, 2022): 1046–57. https://doi.org/10.1056/NEJMoa2116414.Full Text Link to Item
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Pajon, Rolando, Nicole A. Doria-Rose, Xiaoying Shen, Stephen D. Schmidt, Sijy O’Dell, Charlene McDanal, Wenhong Feng, et al. “SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination.” N Engl J Med 386, no. 11 (March 17, 2022): 1088–91. https://doi.org/10.1056/NEJMc2119912.Full Text Link to Item
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Montefiori, David C. “Enhanced immunity after Ad26.COV2.S vaccine breakthrough infection.” Cell Rep Med 3, no. 3 (March 15, 2022): 100579. https://doi.org/10.1016/j.xcrm.2022.100579.Full Text Link to Item
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Mu, Zekun, Kevin Wiehe, Kevin O. Saunders, Rory Henderson, Derek W. Cain, Robert Parks, Diana Martik, et al. “mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice.” Cell Rep 38, no. 11 (March 15, 2022): 110514. https://doi.org/10.1016/j.celrep.2022.110514.Full Text Link to Item
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Gay, Cynthia L., Katherine S. James, Marina Tuyishime, Shane D. Falcinelli, Sarah B. Joseph, Matthew J. Moeser, Brigitte Allard, et al. “Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat.” J Infect Dis 225, no. 5 (March 2, 2022): 856–61. https://doi.org/10.1093/infdis/jiab487.Full Text Link to Item
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Sahoo, Anusmita, Edgar A. Hodge, Celia C. LaBranche, Tiffany M. Styles, Xiaoying Shen, Narayanaiah Cheedarla, Ayalnesh Shiferaw, et al. “Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies.” Cell Rep 38, no. 9 (March 1, 2022): 110436. https://doi.org/10.1016/j.celrep.2022.110436.Full Text Link to Item
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Del Moral-Sánchez, Iván, Rebecca A. Russell, Edith E. Schermer, Christopher A. Cottrell, Joel D. Allen, Alba Torrents de la Peña, Celia C. LaBranche, et al. “High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers.” Npj Vaccines 7, no. 1 (February 28, 2022): 27. https://doi.org/10.1038/s41541-022-00446-4.Full Text Link to Item
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Sangare, K., S. H. Hait, M. Moore, C. Hogge, T. Hoang, M. A. Rahman, D. J. Venzon, et al. “E4orf1 Suppresses E1B-Deleted Adenovirus Vaccine-Induced Immune Responses.” Vaccines 10, no. 2 (February 1, 2022). https://doi.org/10.3390/vaccines10020295.Full Text
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Martinez, David R., Alexandra Schäfer, Sophie Gobeil, Dapeng Li, Gabriela De la Cruz, Robert Parks, Xiaozhi Lu, et al. “A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.” Sci Transl Med 14, no. 629 (January 26, 2022): eabj7125. https://doi.org/10.1126/scitranslmed.abj7125.Full Text Link to Item
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Mielke, Dieter, Sherry Stanfield-Oakley, Bhavesh Borate, Leigh H. Fisher, Katelyn Faircloth, Marina Tuyishime, Kelli Greene, et al. “Selection of HIV Envelope Strains for Standardized Assessments of Vaccine-Elicited Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies.” J Virol 96, no. 2 (January 26, 2022): e0164321. https://doi.org/10.1128/JVI.01643-21.Full Text Link to Item
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Goldblatt, David, Andrew Fiore-Gartland, Marina Johnson, Adam Hunt, Christopher Bengt, Dace Zavadska, Hilda Darta Snipe, et al. “Towards a population-based threshold of protection for COVID-19 vaccines.” Vaccine 40, no. 2 (January 21, 2022): 306–15. https://doi.org/10.1016/j.vaccine.2021.12.006.Full Text Link to Item
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Gilbert, Peter B., David C. Montefiori, Adrian B. McDermott, Youyi Fong, David Benkeser, Weiping Deng, Honghong Zhou, et al. “Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial.” Science 375, no. 6576 (January 7, 2022): 43–50. https://doi.org/10.1126/science.abm3425.Full Text Link to Item
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Lakhashe, Samir K., Mario Amacker, Dinesh Hariraju, Hemant K. Vyas, Kyle S. Morrison, Joshua A. Weiner, Margaret E. Ackerman, et al. “Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges.” Front Immunol 13 (2022): 788619. https://doi.org/10.3389/fimmu.2022.788619.Full Text Link to Item
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Perdiguero, Beatriz, Benedikt Asbach, Carmen E. Gómez, Josef Köstler, Susan W. Barnett, Marguerite Koutsoukos, Deborah E. Weiss, et al. “Early and Long-Term HIV-1 Immunogenicity Induced in Macaques by the Combined Administration of DNA, NYVAC and Env Protein-Based Vaccine Candidates: The AUP512 Study.” Front Immunol 13 (2022): 939627. https://doi.org/10.3389/fimmu.2022.939627.Full Text Link to Item
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Huang, Yunda, Oleg Borisov, Jia Jin Kee, Lindsay N. Carpp, Terri Wrin, Suqin Cai, Marcella Sarzotti-Kelsoe, et al. “Calibration of two validated SARS-CoV-2 pseudovirus neutralization assays for COVID-19 vaccine evaluation.” Sci Rep 11, no. 1 (December 14, 2021): 23921. https://doi.org/10.1038/s41598-021-03154-6.Full Text Link to Item
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Karuna, Shelly, Shuying Sue Li, Shannon Grant, Stephen R. Walsh, Ian Frank, Martin Casapia, Meg Trahey, et al. “Neutralizing antibody responses over time in demographically and clinically diverse individuals recovered from SARS-CoV-2 infection in the United States and Peru: A cohort study.” Plos Med 18, no. 12 (December 2021): e1003868. https://doi.org/10.1371/journal.pmed.1003868.Full Text Link to Item
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Melton, Alexandra, Lara A. Doyle-Meyers, Robert V. Blair, Cecily Midkiff, Hunter J. Melton, Kasi Russell-Lodrigue, Pyone P. Aye, et al. “The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease.” Plos Pathog 17, no. 12 (December 2021): e1010162. https://doi.org/10.1371/journal.ppat.1010162.Full Text Link to Item
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Saunders, Kevin O., Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, et al. “Author Correction: Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.” Npj Vaccines 6, no. 1 (November 6, 2021): 136. https://doi.org/10.1038/s41541-021-00397-2.Full Text Link to Item
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Gilbert, Peter B., Jean-Louis Excler, Georgia D. Tomaras, Lindsay N. Carpp, Barton F. Haynes, Hua-Xin Liao, David C. Montefiori, et al. “Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women.” Plos One 12, no. 5 (2017): e0176428. https://doi.org/10.1371/journal.pone.0176428.Full Text Link to Item
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Gilbert, Peter B., Michal Juraska, Allan C. deCamp, Shelly Karuna, Srilatha Edupuganti, Nyaradzo Mgodi, Deborah J. Donnell, et al. “Basis and Statistical Design of the Passive HIV-1 Antibody Mediated Prevention (AMP) Test-of-Concept Efficacy Trials.” Stat Commun Infect Dis 9, no. 1 (January 2017). https://doi.org/10.1515/scid-2016-0001.Full Text Link to Item
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Hussain, Syed Iqbal, Nandagopal Panneerselvam, Suniti Solomon, Sunil S. Solomon, Kaavya Adam, Ezhilarasi Chandrasekaran, David C. Montefiori, and Balakrishnan Pachamuthu. “Broadly Neutralizing Antibody Responses in a Subset of HIV-1-Infected Individuals in Chennai, India.” J Int Assoc Provid Aids Care 16, no. 2 (2017): 201–8. https://doi.org/10.1177/1545109712467695.Full Text Link to Item
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McCurley, Nathanael P., Arban Domi, Rahul Basu, Kevin O. Saunders, Celia C. LaBranche, David C. Montefiori, Barton F. Haynes, and Harriet L. Robinson. “HIV transmitted/founder vaccines elicit autologous tier 2 neutralizing antibodies for the CD4 binding site.” Plos One 12, no. 10 (2017): e0177863. https://doi.org/10.1371/journal.pone.0177863.Full Text Link to Item
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Astronomo, Rena D., Sampa Santra, Lamar Ballweber-Fleming, Katharine G. Westerberg, Linh Mach, Tiffany Hensley-McBain, Laura Sutherland, et al. “Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection.” Ebiomedicine 14 (December 2016): 97–111. https://doi.org/10.1016/j.ebiom.2016.11.024.Full Text Open Access Copy Link to Item
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Pahar, Bapi, Carys S. Kenway-Lynch, Preston Marx, Sudesh K. Srivastav, Celia LaBranche, David C. Montefiori, and Arpita Das. “Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques.” Virol J 13, no. 1 (December 1, 2016): 200. https://doi.org/10.1186/s12985-016-0652-x.Full Text Link to Item
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Poteet, Ethan, Phoebe Lewis, Changyi Chen, Sam On Ho, Thai Do, SuMing Chiang, Celia Labranche, David Montefiori, Gary Fujii, and Qizhi Yao. “Toll-like receptor 3 adjuvant in combination with virus-like particles elicit a humoral response against HIV.” Vaccine 34, no. 48 (November 21, 2016): 5886–94. https://doi.org/10.1016/j.vaccine.2016.10.036.Full Text Link to Item
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Altenburg, Arwen F., Carolien E. van de Sandt, Stella E. van Trierum, Heidi L. M. De Gruyter, Peter R. W. A. van Run, Ron A. M. Fouchier, Kenny Roose, et al. “Increased Protein Degradation Improves Influenza Virus Nucleoprotein-Specific CD8+ T Cell Activation In Vitro but Not in C57BL/6 Mice.” J Virol 90, no. 22 (November 15, 2016): 10209–19. https://doi.org/10.1128/JVI.01633-16.Full Text Link to Item
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Costa, Matthew R., Justin Pollara, Regina Whitney Edwards, Michael S. Seaman, Miroslaw K. Gorny, David C. Montefiori, Hua-Xin Liao, Guido Ferrari, Shan Lu, and Shixia Wang. “Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001.” J Virol 90, no. 22 (November 15, 2016): 10362–78. https://doi.org/10.1128/JVI.01458-16.Full Text Link to Item
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Kannanganat, Sunil, Linda S. Wyatt, Sailaja Gangadhara, Venkatesarlu Chamcha, Lynette S. Chea, Pamela A. Kozlowski, Celia C. LaBranche, et al. “High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.” J Immunol 197, no. 9 (November 1, 2016): 3586–96. https://doi.org/10.4049/jimmunol.1600629.Full Text Link to Item
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Negri, Donatella, Maria Blasi, Celia LaBranche, Robert Parks, Harikrishnan Balachandran, Michelle Lifton, Xiaoying Shen, et al. “Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques.” Mol Ther 24, no. 11 (November 2016): 2021–32. https://doi.org/10.1038/mt.2016.123.Full Text Open Access Copy Link to Item
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Andersson, Anne-Marie C., Emeline Ragonnaud, Kelly E. Seaton, Sheetal Sawant, Antonella Folgori, Stefano Colloca, Celia Labranche, David C. Montefiori, Georgia D. Tomaras, and Peter J. Holst. “Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations.” Vaccine 34, no. 44 (October 17, 2016): 5344–51. https://doi.org/10.1016/j.vaccine.2016.08.089.Full Text Link to Item
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Gordon, Shari N., Namal P. M. Liyanage, Melvin N. Doster, Monica Vaccari, Diego A. Vargas-Inchaustegui, Poonam Pegu, Luca Schifanella, et al. “Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition.” J Immunol 197, no. 7 (October 1, 2016): 2726–37. https://doi.org/10.4049/jimmunol.1600674.Full Text Link to Item
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Townsley, Samantha, Zeinab Mohamed, Wenjin Guo, Jennifer McKenna, Brad Cleveland, Celia LaBranche, David Beaumont, et al. “Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization.” J Virol 90, no. 19 (October 1, 2016): 8644–60. https://doi.org/10.1128/JVI.00853-16.Full Text Link to Item
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Klasse, P. J., Celia C. LaBranche, Thomas J. Ketas, Gabriel Ozorowski, Albert Cupo, Pavel Pugach, Rajesh P. Ringe, et al. “Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.” Plos Pathog 12, no. 9 (September 2016): e1005864. https://doi.org/10.1371/journal.ppat.1005864.Full Text Link to Item
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Moody, M Anthony, Isabela Pedroza-Pacheco, Nathan A. Vandergrift, Cecilia Chui, Krissey E. Lloyd, Robert Parks, Kelly A. Soderberg, et al. “Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies.” Sci Immunol 1, no. 1 (July 29, 2016): aag0851. https://doi.org/10.1126/sciimmunol.aag0851.Full Text Link to Item
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Rademeyer, Cecilia, Bette Korber, Michael S. Seaman, Elena E. Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J. Sheward, et al. “Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.” Plos Pathog 12, no. 7 (July 2016): e1005742. https://doi.org/10.1371/journal.ppat.1005742.Full Text Link to Item
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Vaccari, Monica, Shari N. Gordon, Slim Fourati, Luca Schifanella, Namal P. M. Liyanage, Mark Cameron, Brandon F. Keele, et al. “Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.” Nat Med 22, no. 7 (July 2016): 762–70. https://doi.org/10.1038/nm.4105.Full Text Link to Item
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Li, Hui, Shuyi Wang, Rui Kong, Wenge Ding, Fang-Hua Lee, Zahra Parker, Eunlim Kim, et al. “Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.” Proc Natl Acad Sci U S A 113, no. 24 (June 14, 2016): E3413–22. https://doi.org/10.1073/pnas.1606636113.Full Text Link to Item
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Gray, Glenda E., Kenneth H. Mayer, Marnie L. Elizaga, Linda-Gail Bekker, Mary Allen, Lynn Morris, David Montefiori, et al. “Subtype C gp140 Vaccine Boosts Immune Responses Primed by the South African AIDS Vaccine Initiative DNA-C2 and MVA-C HIV Vaccines after More than a 2-Year Gap.” Clin Vaccine Immunol 23, no. 6 (June 2016): 496–506. https://doi.org/10.1128/CVI.00717-15.Full Text Link to Item
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Nelson, Cody S., Justin Pollara, Erika L. Kunz, Thomas L. Jeffries, Ryan Duffy, Charles Beck, Lisa Stamper, et al. “Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk.” J Virol 90, no. 10 (May 15, 2016): 4951–65. https://doi.org/10.1128/JVI.00335-16.Full Text Link to Item
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Swanstrom, Adrienne E., Beth Haggarty, Andrea P. O. Jordan, Josephine Romano, George J. Leslie, Pyone P. Aye, Preston A. Marx, et al. “Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus.” J Virol 90, no. 10 (May 15, 2016): 4966–80. https://doi.org/10.1128/JVI.02851-15.Full Text Link to Item
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Willis, Jordan R., Jessica A. Finn, Bryan Briney, Gopal Sapparapu, Vidisha Singh, Hannah King, Celia C. LaBranche, David C. Montefiori, Jens Meiler, and James E. Crowe. “Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization.” Proc Natl Acad Sci U S A 113, no. 16 (April 19, 2016): 4446–51. https://doi.org/10.1073/pnas.1518405113.Full Text Link to Item
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Bonsignori, Mattia, Tongqing Zhou, Zizhang Sheng, Lei Chen, Feng Gao, M Gordon Joyce, Gabriel Ozorowski, et al. “Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.” Cell 165, no. 2 (April 7, 2016): 449–63. https://doi.org/10.1016/j.cell.2016.02.022.Full Text Link to Item
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Asbach, Benedikt, Alexander Kliche, Josef Köstler, Beatriz Perdiguero, Mariano Esteban, Bertram L. Jacobs, David C. Montefiori, et al. “Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens.” J Virol 90, no. 8 (April 2016): 4133–49. https://doi.org/10.1128/JVI.03135-15.Full Text Open Access Copy Link to Item
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Hessell, Ann J., Delphine C. Malherbe, Franco Pissani, Sean McBurney, Shelly J. Krebs, Michelle Gomes, Shilpi Pandey, et al. “Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens.” J Immunol 196, no. 7 (April 1, 2016): 3064–78. https://doi.org/10.4049/jimmunol.1500527.Full Text Link to Item
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Paneerselvam, N., S. Iqbal, S. Solomon, S. S. Solomon, D. C. Montefiori, and P. Balakrishnan. “Elite neutralizers among HIV-1 Subtype-C infected individuals from southern India.” International Journal of Infectious Diseases 45 (April 2016): 268–268. https://doi.org/10.1016/j.ijid.2016.02.597.Full Text
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Wagh, Kshitij, Tanmoy Bhattacharya, Carolyn Williamson, Alex Robles, Madeleine Bayne, Jetta Garrity, Michael Rist, et al. “Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection.” Plos Pathog 12, no. 3 (March 2016): e1005520. https://doi.org/10.1371/journal.ppat.1005520.Full Text Link to Item
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Walsh, Stephen R., Zoe Moodie, Andrew J. Fiore-Gartland, Cecilia Morgan, Marissa B. Wilck, Scott M. Hammer, Susan P. Buchbinder, et al. “Vaccination With Heterologous HIV-1 Envelope Sequences and Heterologous Adenovirus Vectors Increases T-Cell Responses to Conserved Regions: HVTN 083.” J Infect Dis 213, no. 4 (February 15, 2016): 541–50. https://doi.org/10.1093/infdis/jiv496.Full Text Link to Item
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Khattar, Sunil K., Anthony L. DeVico, Celia C. LaBranche, Aruna Panda, David C. Montefiori, and Siba K. Samal. “Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins.” J Virol 90, no. 3 (February 1, 2016): 1682–86. https://doi.org/10.1128/JVI.02847-15.Full Text Link to Item
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Bradley, Todd, Daniela Fera, Jinal Bhiman, Leila Eslamizar, Xiaozhi Lu, Kara Anasti, Ruijung Zhang, et al. “Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site.” Cell Rep 14, no. 1 (January 5, 2016): 43–54. https://doi.org/10.1016/j.celrep.2015.12.017.Full Text Link to Item
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Zambonelli, Carlo, Antu K. Dey, Susan Hilt, Samuel Stephenson, Eden P. Go, Daniel F. Clark, Mark Wininger, et al. “Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa.” Plos One 11, no. 7 (2016): e0157391. https://doi.org/10.1371/journal.pone.0157391.Full Text Link to Item
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Zurawski, Gerard, Sandra Zurawski, Anne-Laure Flamar, Laura Richert, Ralf Wagner, Georgia D. Tomaras, David C. Montefiori, et al. “Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques.” Plos One 11, no. 4 (2016): e0153484. https://doi.org/10.1371/journal.pone.0153484.Full Text Link to Item
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Boehme, Karl W., Mine’ Ikizler, Jason A. Iskarpatyoti, J Denise Wetzel, Jordan Willis, James E. Crowe, Celia C. LaBranche, David C. Montefiori, Gregory J. Wilson, and Terence S. Dermody. “Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1.” Msphere 1, no. 3 (2016). https://doi.org/10.1128/mSphere.00086-16.Full Text Link to Item
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Chamcha, Venkateswarlu, Sunil Kannanganat, Sailaja Gangadhara, Rafiq Nabi, Pamela A. Kozlowski, David C. Montefiori, Celia C. LaBranche, et al. “Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine.” Open Forum Infect Dis 3, no. 1 (January 2016): ofw034. https://doi.org/10.1093/ofid/ofw034.Full Text Link to Item
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Churchyard, Gavin, Koleka Mlisana, Shelly Karuna, Anna-Lise Williamson, Carolyn Williamson, Lynn Morris, Georgia D. Tomaras, et al. “Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants.” Plos One 11, no. 9 (2016): e0161753. https://doi.org/10.1371/journal.pone.0161753.Full Text Link to Item
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Kutzler, M. A., M. C. Wise, N. A. Hutnick, Z. Moldoveanu, M. Hunter, M. Reuter, S. Yuan, et al. “Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge.” Mucosal Immunol 9, no. 1 (January 2016): 13–23. https://doi.org/10.1038/mi.2015.31.Full Text Link to Item
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Rosenberg, Yvonne J., David C. Montefiori, Celia C. LaBranche, Mark G. Lewis, Markus Sack, Jonathan P. Lees, and Xiaoming Jiang. “Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques.” Plos One 11, no. 3 (2016): e0152760. https://doi.org/10.1371/journal.pone.0152760.Full Text Link to Item
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Arrildt, Kathryn T., Celia C. LaBranche, Sarah B. Joseph, Elena N. Dukhovlinova, William D. Graham, Li-Hua Ping, Gretja Schnell, et al. “Phenotypic Correlates of HIV-1 Macrophage Tropism.” J Virol 89, no. 22 (November 2015): 11294–311. https://doi.org/10.1128/JVI.00946-15.Full Text Link to Item
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Dunkel, Amber, Shixue Shen, Celia C. LaBranche, David Montefiori, and James P. McGettigan. “A Bivalent, Chimeric Rabies Virus Expressing Simian Immunodeficiency Virus Envelope Induces Multifunctional Antibody Responses.” Aids Res Hum Retroviruses 31, no. 11 (November 2015): 1126–38. https://doi.org/10.1089/AID.2014.0319.Full Text Link to Item
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Menon, Veena, Rangasamy Sneha Priya, Celia Labranche, David Montefiori, Sundarasamy Mahalingam, Vaniambadi S. Kalyanaraman, and Ranajit Pal. “Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques.” J Med Primatol 44, no. 5 (October 2015): 275–85. https://doi.org/10.1111/jmp.12178.Full Text Link to Item
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Murray, Marta K., Victor A. Teran, Jean-Philippe Chapleau, Baomin Wang, Su Hyon Kim, Celia C. LaBranche, Jonathan Richard, David C. Montefiori, Andrés Finzi, and Wen Yuan. “Soluble Envelope Glycoprotein Trimers from a CD4-Independent HIV-1 Elicit Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Guinea Pigs.” J Virol 89, no. 20 (October 2015): 10707–11. https://doi.org/10.1128/JVI.01642-15.Full Text Link to Item
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Webb, Nicholas E., David C. Montefiori, and Benhur Lee. “Dose-response curve slope helps predict therapeutic potency and breadth of HIV broadly neutralizing antibodies.” Nat Commun 6 (September 29, 2015): 8443. https://doi.org/10.1038/ncomms9443.Full Text Link to Item
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Sliepen, Kwinten, Gabriel Ozorowski, Judith A. Burger, Thijs van Montfort, Melissa Stunnenberg, Celia LaBranche, David C. Montefiori, John P. Moore, Andrew B. Ward, and Rogier W. Sanders. “Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity.” Retrovirology 12 (September 26, 2015): 82. https://doi.org/10.1186/s12977-015-0210-4.Full Text Link to Item
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Moody, M Anthony, Feng Gao, Thaddeus C. Gurley, Joshua D. Amos, Amit Kumar, Bhavna Hora, Dawn J. Marshall, et al. “Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses.” Cell Host Microbe 18, no. 3 (September 9, 2015): 354–62. https://doi.org/10.1016/j.chom.2015.08.006.Full Text Link to Item
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Wise, Megan C., Natalie A. Hutnick, Justin Pollara, Devin J. F. Myles, Constance Williams, Jian Yan, Celia C. LaBranche, et al. “An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates.” J Virol 89, no. 18 (September 2015): 9154–66. https://doi.org/10.1128/JVI.00652-15.Full Text Link to Item
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García-Arriaza, Juan, Beatriz Perdiguero, Jonathan Heeney, Michael Seaman, David C. Montefiori, Celia Labranche, Nicole L. Yates, et al. “Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates.” J Virol 89, no. 16 (August 2015): 8525–39. https://doi.org/10.1128/JVI.01265-15.Full Text Link to Item
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Shen, Xiaoying, Ryan Duffy, Robert Howington, Alethea Cope, Shanmugalakshmi Sadagopal, Haesun Park, Ranajit Pal, et al. “Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.” J Virol 89, no. 16 (August 2015): 8643–50. https://doi.org/10.1128/JVI.03635-14.Full Text Link to Item
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Tomaras, Georgia D., Guido Ferrari, Xiaoying Shen, S Munir Alam, Hua-Xin Liao, Justin Pollara, Mattia Bonsignori, et al. “Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.” Proc Natl Acad Sci U S A 110, no. 22 (May 28, 2013): 9019–24. https://doi.org/10.1073/pnas.1301456110.Full Text Link to Item
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Perez, Lautaro G., Susan Zolla-Pazner, and David C. Montefiori. “Antibody-DEPENDENT, FcγRI-mediated neutralization of HIV-1 in TZM-bl cells occurs independently of phagocytosis.” J Virol 87, no. 9 (May 2013): 5287–90. https://doi.org/10.1128/JVI.00278-13.Full Text Link to Item
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Bhattacharyya, Sanchari, Pranveer Singh, Ujjwal Rathore, Mansi Purwar, Denise Wagner, Heather Arendt, Joanne DeStefano, et al. “Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies.” J Biol Chem 288, no. 14 (April 5, 2013): 9815–25. https://doi.org/10.1074/jbc.M112.425959.Full Text Link to Item
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Manrique, Mariana, Pamela A. Kozlowski, Antonio Cobo-Molinos, Shainn-Wei Wang, Robert L. Wilson, David C. Montefiori, Angela Carville, and Anna Aldovini. “Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes.” J Virol 87, no. 8 (April 2013): 4738–50. https://doi.org/10.1128/JVI.03531-12.Full Text Link to Item
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Vaccari, Monica, Brandon F. Keele, Steven E. Bosinger, Melvin N. Doster, Zhong-Min Ma, Justin Pollara, Anna Hryniewicz, et al. “Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure.” J Virol 87, no. 6 (March 2013): 3538–48. https://doi.org/10.1128/JVI.02863-12.Full Text Link to Item
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Russell, Elizabeth S., Suany Ojeda, Genevieve G. Fouda, Steven R. Meshnick, David Montefiori, Sallie R. Permar, and Ronald Swanstrom. “Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes.” Aids Res Hum Retroviruses 29, no. 3 (March 2013): 511–15. https://doi.org/10.1089/AID.2012.0197.Full Text Link to Item
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Pegu, Poonam, Monica Vaccari, Shari Gordon, Brandon F. Keele, Melvin Doster, Yongjun Guan, Guido Ferrari, et al. “Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial.” J Virol 87, no. 3 (February 2013): 1708–19. https://doi.org/10.1128/JVI.02544-12.Full Text Link to Item
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Liao, Hua-Xin, Mattia Bonsignori, S Munir Alam, Jason S. McLellan, Georgia D. Tomaras, M Anthony Moody, Daniel M. Kozink, et al. “Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2.” Immunity 38, no. 1 (January 24, 2013): 176–86. https://doi.org/10.1016/j.immuni.2012.11.011.Full Text Link to Item
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Fouda, Genevieve G., Tatenda Mahlokozera, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Gerald Learn, Surender B. Kumar, S Moses Dennison, et al. “Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants.” Retrovirology 10 (January 10, 2013): 3. https://doi.org/10.1186/1742-4690-10-3.Full Text Open Access Copy Link to Item
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Alexander, Jeff, Jason Mendy, Lo Vang, Jenny B. Avanzini, Fermin Garduno, Darly J. Manayani, Glenn Ishioka, et al. “Pre-clinical development of a recombinant, replication-competent adenovirus serotype 4 vector vaccine expressing HIV-1 envelope 1086 clade C.” Plos One 8, no. 12 (2013): e82380. https://doi.org/10.1371/journal.pone.0082380.Full Text Link to Item
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Bontjer, Ilja, Mark Melchers, Tommy Tong, Thijs van Montfort, Dirk Eggink, David Montefiori, William C. Olson, et al. “Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers.” Plos One 8, no. 6 (2013): e67484. https://doi.org/10.1371/journal.pone.0067484.Full Text Link to Item
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Chenine, Agnès-Laurence, Lindsay Wieczorek, Eric Sanders-Buell, Maggie Wesberry, Teresa Towle, Devin M. Pillis, Sebastian Molnar, et al. “Impact of HIV-1 backbone on neutralization sensitivity: neutralization profiles of heterologous envelope glycoproteins expressed in native subtype C and CRF01_AE backbone.” Plos One 8, no. 11 (2013): e76104. https://doi.org/10.1371/journal.pone.0076104.Full Text Link to Item
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Kassa, Aemro, Antu K. Dey, Pampi Sarkar, Celia Labranche, Eden P. Go, Daniel F. Clark, Yide Sun, et al. “Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein.” Plos One 8, no. 10 (2013): e76139. https://doi.org/10.1371/journal.pone.0076139.Full Text Link to Item
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Khattar, Sunil K., Sweety Samal, Celia C. LaBranche, David C. Montefiori, Peter L. Collins, and Siba K. Samal. “Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector.” Plos One 8, no. 10 (2013): e78521. https://doi.org/10.1371/journal.pone.0078521.Full Text Link to Item
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Rosenberg, Yvonne, Markus Sack, David Montefiori, Donald Forthal, Lingjun Mao, Segundo Hernandez-Abanto, Lori Urban, Gary Landucci, Rainer Fischer, and Xiaoming Jiang. “Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems.” Plos One 8, no. 3 (2013): e58724. https://doi.org/10.1371/journal.pone.0058724.Full Text Link to Item
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Venditto, Vincent J., Douglas S. Watson, Michael Motion, David Montefiori, and Francis C. Szoka. “Rational design of membrane proximal external region lipopeptides containing chemical modifications for HIV-1 vaccination.” Clin Vaccine Immunol 20, no. 1 (January 2013): 39–45. https://doi.org/10.1128/CVI.00615-12.Full Text Link to Item
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Weaver, Eric A., Pramod N. Nehete, Bharti P. Nehete, Guojun Yang, Stephanie J. Buchl, Patrick W. Hanley, Donna Palmer, et al. “Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV.” Plos One 8, no. 7 (2013): e67574. https://doi.org/10.1371/journal.pone.0067574.Full Text Link to Item
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Winckelmann, Anni A., Lærke V. Munk-Petersen, Thomas A. Rasmussen, Jesper Melchjorsen, Thomas J. Hjelholt, David Montefiori, Lars Østergaard, Ole S. Søgaard, and Martin Tolstrup. “Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients.” Plos One 8, no. 4 (2013): e62074. https://doi.org/10.1371/journal.pone.0062074.Full Text Link to Item
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Gottardo, Raphael, Robert T. Bailer, Bette T. Korber, S. Gnanakaran, Joshua Phillips, Xiaoying Shen, Georgia D. Tomaras, et al. “Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial.” Plos One 8, no. 9 (2013): e75665. https://doi.org/10.1371/journal.pone.0075665.Full Text Link to Item
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McLinden, Robert J., Celia C. Labranche, Agnès-Laurence Chenine, Victoria R. Polonis, Michael A. Eller, Lindsay Wieczorek, Christina Ochsenbauer, et al. “Detection of HIV-1 neutralizing antibodies in a human CD4⁺/CXCR4⁺/CCR5⁺ T-lymphoblastoid cell assay system.” Plos One 8, no. 11 (2013): e77756. https://doi.org/10.1371/journal.pone.0077756.Full Text Link to Item
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Zolla-Pazner, Susan, Allan C. deCamp, Timothy Cardozo, Nicos Karasavvas, Raphael Gottardo, Constance Williams, Daryl E. Morris, et al. “Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial.” Plos One 8, no. 1 (2013): e53629. https://doi.org/10.1371/journal.pone.0053629.Full Text Link to Item
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Shingai, Masashi, Olivia K. Donau, Stephen D. Schmidt, Rajeev Gautam, Ronald J. Plishka, Alicia Buckler-White, Reza Sadjadpour, et al. “Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains.” Proc Natl Acad Sci U S A 109, no. 48 (November 27, 2012): 19769–74. https://doi.org/10.1073/pnas.1217443109.Full Text Link to Item
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Bonsignori, Mattia, Justin Pollara, M Anthony Moody, Michael D. Alpert, Xi Chen, Kwan-Ki Hwang, Peter B. Gilbert, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family.” J Virol 86, no. 21 (November 2012): 11521–32. https://doi.org/10.1128/JVI.01023-12.Full Text Link to Item
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Fukazawa, Yoshinori, Haesun Park, Mark J. Cameron, Francois Lefebvre, Richard Lum, Noel Coombes, Eisa Mahyari, et al. “Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.” Nat Med 18, no. 11 (November 2012): 1673–81. https://doi.org/10.1038/nm.2934.Full Text Link to Item
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Jalah, Rashmi, Vainav Patel, Viraj Kulkarni, Margherita Rosati, Candido Alicea, Brunda Ganneru, Agneta von Gegerfelt, et al. “IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques.” Hum Vaccin Immunother 8, no. 11 (November 1, 2012): 1620–29. https://doi.org/10.4161/hv.21407.Full Text Link to Item
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Karasavvas, Nicos, Erik Billings, Mangala Rao, Constance Williams, Susan Zolla-Pazner, Robert T. Bailer, Richard A. Koup, et al. “The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120.” Aids Res Hum Retroviruses 28, no. 11 (November 2012): 1444–57. https://doi.org/10.1089/aid.2012.0103.Full Text Link to Item
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Hu, Xintao, Kunxue Hong, Chunhong Zhao, Yang Zheng, Liying Ma, Yuhua Ruan, Hongmei Gao, et al. “Profiles of neutralizing antibody response in chronically human immunodeficiency virus type 1 clade B'-infected former plasma donors from China naive to antiretroviral therapy.” J Gen Virol 93, no. Pt 10 (October 2012): 2267–78. https://doi.org/10.1099/vir.0.043802-0.Full Text Link to Item
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Montefiori, David C., Chitraporn Karnasuta, Ying Huang, Hasan Ahmed, Peter Gilbert, Mark S. de Souza, Robert McLinden, et al. “Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials.” J Infect Dis 206, no. 3 (August 1, 2012): 431–41. https://doi.org/10.1093/infdis/jis367.Full Text Link to Item
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Gautam, Rajeev, Yoshiaki Nishimura, Wendy R. Lee, Olivia Donau, Alicia Buckler-White, Masashi Shingai, Reza Sadjadpour, et al. “Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies.” J Virol 86, no. 16 (August 2012): 8516–26. https://doi.org/10.1128/JVI.00644-12.Full Text Link to Item
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Van Rompay, Koen K. A., Kristin A. Trott, Kartika Jayashankar, Yongzhi Geng, Celia C. LaBranche, Jeffrey A. Johnson, Gary Landucci, et al. “Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.” Retrovirology 9 (July 17, 2012): 57. https://doi.org/10.1186/1742-4690-9-57.Full Text Link to Item
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Moody, M Anthony, Nicole L. Yates, Joshua D. Amos, Mark S. Drinker, Joshua A. Eudailey, Thaddeus C. Gurley, Dawn J. Marshall, et al. “HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.” J Virol 86, no. 14 (July 2012): 7496–7507. https://doi.org/10.1128/JVI.00426-12.Full Text Link to Item
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Lynch, Rebecca M., Lillian Tran, Mark K. Louder, Stephen D. Schmidt, Myron Cohen, Myron CHAVI 001 Clinical Team Members, Rebecca Dersimonian, et al. “The development of CD4 binding site antibodies during HIV-1 infection.” J Virol 86, no. 14 (July 2012): 7588–95. https://doi.org/10.1128/JVI.00734-12.Full Text Link to Item
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Schell, John B., Kapil Bahl, Nina F. Rose, Linda Buonocore, Meredith Hunter, Preston A. Marx, Celia C. LaBranche, David C. Montefiori, and John K. Rose. “Viral vectored granulocyte-macrophage colony stimulating factor inhibits vaccine protection in an SIV challenge model: protection correlates with neutralizing antibody.” Vaccine 30, no. 28 (June 13, 2012): 4233–39. https://doi.org/10.1016/j.vaccine.2012.04.046.Full Text Link to Item
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Dey, Antu K., Brian Burke, Yide Sun, Karin Hartog, Jonathan L. Heeney, David Montefiori, Indresh K. Srivastava, and Susan W. Barnett. “Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein.” Vaccine 30, no. 17 (April 5, 2012): 2749–59. https://doi.org/10.1016/j.vaccine.2012.02.027.Full Text Link to Item
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Haynes, Barton F., Peter B. Gilbert, M Juliana McElrath, Susan Zolla-Pazner, Georgia D. Tomaras, S Munir Alam, David T. Evans, et al. “Immune-correlates analysis of an HIV-1 vaccine efficacy trial.” N Engl J Med 366, no. 14 (April 5, 2012): 1275–86. https://doi.org/10.1056/NEJMoa1113425.Full Text Link to Item
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Bonsignori, Mattia, David C. Montefiori, Xueling Wu, Xi Chen, Kwan-Ki Hwang, Chun-Yen Tsao, Daniel M. Kozink, et al. “Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design.” J Virol 86, no. 8 (April 2012): 4688–92. https://doi.org/10.1128/JVI.07163-11.Full Text Open Access Copy Link to Item
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Xiao, Peng, L Jean Patterson, Seraphin Kuate, Egidio Brocca-Cofano, Michael A. Thomas, David Venzon, Jun Zhao, et al. “Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac251) challenge.” J Virol 86, no. 8 (April 2012): 4644–57. https://doi.org/10.1128/JVI.06812-11.Full Text Link to Item
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Melchers, Mark, Ilja Bontjer, Tommy Tong, Nancy P. Y. Chung, Per Johan Klasse, Dirk Eggink, David C. Montefiori, et al. “Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.” J Virol 86, no. 5 (March 2012): 2488–2500. https://doi.org/10.1128/JVI.06259-11.Full Text Link to Item
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Cox, Josephine H., Maria G. Ferrari, Patricia Earl, James R. Lane, Linda L. Jagodzinski, Victoria R. Polonis, Ellen G. Kuta, et al. “Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.” Vaccine 30, no. 10 (February 27, 2012): 1830–40. https://doi.org/10.1016/j.vaccine.2011.12.131.Full Text Link to Item
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Lai, Lilin, Sue-Fen Kwa, Pamela A. Kozlowski, David C. Montefiori, Tracy L. Nolen, Michael G. Hudgens, Welkin E. Johnson, et al. “SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses.” Vaccine 30, no. 9 (February 21, 2012): 1737–45. https://doi.org/10.1016/j.vaccine.2011.12.026.Full Text Link to Item
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Lavine, Christy L., Socheata Lao, David C. Montefiori, Barton F. Haynes, Joseph G. Sodroski, Xinzhen Yang, and Xinzhen NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI). “High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection.” J Virol 86, no. 4 (February 2012): 2153–64. https://doi.org/10.1128/JVI.06201-11.Full Text Link to Item
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Todd, Christopher A., Kelli M. Greene, Xuesong Yu, Daniel A. Ozaki, Hongmei Gao, Yunda Huang, Maggie Wang, et al. “Development and implementation of an international proficiency testing program for a neutralizing antibody assay for HIV-1 in TZM-bl cells.” J Immunol Methods 375, no. 1–2 (January 31, 2012): 57–67. https://doi.org/10.1016/j.jim.2011.09.007.Full Text Link to Item
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Rosario, Maximillian, Nicola Borthwick, Guillaume B. Stewart-Jones, Alice Mbewe-Mvula, Anne Bridgeman, Stefano Colloca, David Montefiori, et al. “Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques.” Aids 26, no. 3 (January 28, 2012): 275–84. https://doi.org/10.1097/QAD.0b013e32834ed9b2.Full Text Link to Item
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Rasmussen, Robert A., Nagadenahalli B. Siddappa, Samir K. Lakhashe, Jennifer Watkins, François Villinger, Chris Ibegbu, Ruth H. Florese, et al. “High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine and boosted by live-virus exposure: prevention of viremia.” Aids 26, no. 2 (January 14, 2012): 149–55. https://doi.org/10.1097/QAD.0b013e32834d3c4f.Full Text Link to Item
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Bar, Katharine J., Chun-yen Tsao, Shilpa S. Iyer, Julie M. Decker, Yongping Yang, Mattia Bonsignori, Xi Chen, et al. “Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape.” Plos Pathog 8, no. 5 (2012): e1002721. https://doi.org/10.1371/journal.ppat.1002721.Full Text Link to Item
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Dey, Antu K., Brian Burke, Yide Sun, Klara Sirokman, Avishek Nandi, Karin Hartog, Ying Lian, et al. “Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein.” Plos One 7, no. 1 (2012): e30233. https://doi.org/10.1371/journal.pone.0030233.Full Text Link to Item
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Heyndrickx, Leo, Alan Heath, Enas Sheik-Khalil, Jose Alcami, Vera Bongertz, Marianne Jansson, Mauro Malnati, et al. “International network for comparison of HIV neutralization assays: the NeutNet report II.” Plos One 7, no. 5 (2012): e36438. https://doi.org/10.1371/journal.pone.0036438.Full Text Link to Item
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Jaworski, Juan Pablo, Shelly J. Krebs, Maria Trovato, Dina N. Kovarik, Zachary Brower, William F. Sutton, Garrett Waagmeester, et al. “Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells.” Plos One 7, no. 2 (2012): e31464. https://doi.org/10.1371/journal.pone.0031464.Full Text Link to Item
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Kobie, James J., Danielle C. Alcena, Bo Zheng, Peter Bryk, Jonelle L. Mattiacio, Matthew Brewer, Celia Labranche, et al. “9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity.” Plos One 7, no. 4 (2012): e35356. https://doi.org/10.1371/journal.pone.0035356.Full Text Link to Item
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Lai, Rachel P. J., Michael S. Seaman, Paul Tonks, Frank Wegmann, David J. Seilly, Simon D. W. Frost, Celia C. LaBranche, et al. “Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants.” Plos One 7, no. 4 (2012): e35083. https://doi.org/10.1371/journal.pone.0035083.Full Text Link to Item
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Ozaki, Daniel A., Hongmei Gao, Christopher A. Todd, Kelli M. Greene, David C. Montefiori, and Marcella Sarzotti-Kelsoe. “International technology transfer of a GCLP-compliant HIV-1 neutralizing antibody assay for human clinical trials.” Plos One 7, no. 1 (2012): e30963. https://doi.org/10.1371/journal.pone.0030963.Full Text Link to Item
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Parrish, Nicholas F., Craig B. Wilen, Lauren B. Banks, Shilpa S. Iyer, Jennifer M. Pfaff, Jesus F. Salazar-Gonzalez, Maria G. Salazar, et al. “Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7.” Plos Pathog 8, no. 5 (2012): e1002686. https://doi.org/10.1371/journal.ppat.1002686.Full Text Link to Item
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Schultz, Anke, Stefanie Koch, Martina Fuss, Angela S. Mazzotta, Marcella Sarzotti-Kelsoe, Daniel A. Ozaki, David C. Montefiori, Hagen von Briesen, Heiko Zimmermann, and Andreas Meyerhans. “An automated HIV-1 Env-pseudotyped virus production for global HIV vaccine trials.” Plos One 7, no. 12 (2012): e51715. https://doi.org/10.1371/journal.pone.0051715.Full Text Link to Item
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Sellhorn, George, Zane Kraft, Zachary Caldwell, Katharine Ellingson, Christine Mineart, Michael S. Seaman, David C. Montefiori, Eliza Lagerquist, and Leonidas Stamatatos. “Engineering, expression, purification, and characterization of stable clade A/B recombinant soluble heterotrimeric gp140 proteins.” J Virol 86, no. 1 (January 2012): 128–42. https://doi.org/10.1128/JVI.06363-11.Full Text Link to Item
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Sholukh, Anton M., Muhammad M. Mukhtar, Michael Humbert, Sosthène S. Essono, Jennifer D. Watkins, Hemant K. Vyas, Vivekanandan Shanmuganathan, et al. “Isolation of monoclonal antibodies with predetermined conformational epitope specificity.” Plos One 7, no. 6 (2012): e38943. https://doi.org/10.1371/journal.pone.0038943.Full Text Link to Item
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Brown, Bruce K., Lindsay Wieczorek, Gustavo Kijak, Kara Lombardi, Jeffrey Currier, Maggie Wesberry, John C. Kappes, et al. “The role of natural killer (NK) cells and NK cell receptor polymorphisms in the assessment of HIV-1 neutralization.” Plos One 7, no. 4 (2012): e29454. https://doi.org/10.1371/journal.pone.0029454.Full Text Link to Item
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Bialuk, Izabela, Stephen Whitney, Vibeke Andresen, Ruth H. Florese, Janos Nacsa, Valentina Cecchinato, Valerio W. Valeri, et al. “Vaccine induced antibodies to the first variable loop of human immunodeficiency virus type 1 gp120, mediate antibody-dependent virus inhibition in macaques.” Vaccine 30, no. 1 (December 9, 2011): 78–94. https://doi.org/10.1016/j.vaccine.2011.10.040.Full Text Link to Item
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Tomaras, Georgia D., James M. Binley, Elin S. Gray, Emma T. Crooks, Keiko Osawa, Penny L. Moore, Nancy Tumba, et al. “Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals.” J Virol 85, no. 21 (November 2011): 11502–19. https://doi.org/10.1128/JVI.05363-11.Full Text Link to Item
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Liu, Pinghuang, R Glenn Overman, Nicole L. Yates, S Munir Alam, Nathan Vandergrift, Yue Chen, Frederik Graw, et al. “Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infection.” J Virol 85, no. 21 (November 2011): 11196–207. https://doi.org/10.1128/JVI.05601-11.Full Text Link to Item
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Zhu, Zhongyu, Haiyan Rebekah Qin, Weizao Chen, Qi Zhao, Xiaoying Shen, Robert Schutte, Yanping Wang, et al. “Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies.” J Virol 85, no. 21 (November 2011): 11401–8. https://doi.org/10.1128/JVI.05312-11.Full Text Link to Item
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Liao, Hua-Xin, Xi Chen, Supriya Munshaw, Ruijun Zhang, Dawn J. Marshall, Nathan Vandergrift, John F. Whitesides, et al. “Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated.” J Exp Med 208, no. 11 (October 24, 2011): 2237–49. https://doi.org/10.1084/jem.20110363.Full Text Open Access Copy Link to Item
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Bonsignori, Mattia, Kwan-Ki Hwang, Xi Chen, Chun-Yen Tsao, Lynn Morris, Elin Gray, Dawn J. Marshall, et al. “Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors.” J Virol 85, no. 19 (October 2011): 9998–10009. https://doi.org/10.1128/JVI.05045-11.Full Text Link to Item
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Fouda, Genevieve G., Nicole L. Yates, Justin Pollara, Xiaoying Shen, Glenn R. Overman, Tatenda Mahlokozera, Andrew B. Wilks, et al. “HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.” J Virol 85, no. 18 (September 2011): 9555–67. https://doi.org/10.1128/JVI.05174-11.Full Text Open Access Copy Link to Item
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Tang, Haili, James E. Robinson, S. Gnanakaran, Ming Li, Eric S. Rosenberg, Lautaro G. Perez, Barton F. Haynes, et al. “epitopes immediately below the base of the V3 loop of gp120 as targets for the initial autologous neutralizing antibody response in two HIV-1 subtype B-infected individuals.” J Virol 85, no. 18 (September 2011): 9286–99. https://doi.org/10.1128/JVI.02286-10.Full Text Link to Item
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Wilen, Craig B., Nicholas F. Parrish, Jennifer M. Pfaff, Julie M. Decker, Elizabeth A. Henning, Hillel Haim, Josiah E. Petersen, et al. “Phenotypic and immunologic comparison of clade B transmitted/founder and chronic HIV-1 envelope glycoproteins.” J Virol 85, no. 17 (September 2011): 8514–27. https://doi.org/10.1128/JVI.00736-11.Full Text Link to Item
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Lai, Weihong, Li Huang, Phong Ho, David Montefiori, and Chin-Ho Chen. “The role of dynamin in HIV type 1 Env-mediated cell-cell fusion.” Aids Res Hum Retroviruses 27, no. 9 (September 2011): 1013–17. https://doi.org/10.1089/AID.2010.0259.Full Text Link to Item
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Lakhashe, Samir K., Vijayakumar Velu, Gaia Sciaranghella, Nagadenahalli B. Siddappa, Janet M. Dipasquale, Girish Hemashettar, John K. Yoon, et al. “Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges.” Vaccine 29, no. 34 (August 5, 2011): 5611–22. https://doi.org/10.1016/j.vaccine.2011.06.017.Full Text Link to Item
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Ourmanov, Ilnour, Yanfang Zheng, Mattias N. E. Forsell, Audrey L. Kinter, Simoy Goldstein, David C. Montefiori, Richard T. Wyatt, and Vanessa M. Hirsch. “STUDIES OF ENV-BASED RECOMBINANT IMMUNOGENS AND ROLE OF NEUTRALIZING ANTIBODY IN THE SIV MACAQUE MODEL.” Journal of Medical Primatology 40, no. 4 (August 1, 2011): 269–70.Link to Item
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Pandrea, Ivona, Thaidra Gaufin, Rajeev Gautam, Jan Kristoff, Daniel Mandell, David Montefiori, Brandon F. Keele, Ruy M. Ribeiro, Ronald S. Veazey, and Cristian Apetrei. “Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion.” Plos Pathog 7, no. 8 (August 2011): e1002170. https://doi.org/10.1371/journal.ppat.1002170.Full Text Link to Item
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Revilla, Ana, Elena Delgado, Elizabeth C. Christian, Justin Dalrymple, Yolanda Vega, Cristina Carrera, María González-Galeano, et al. “Construction and phenotypic characterization of HIV type 1 functional envelope clones of subtypes G and F.” Aids Res Hum Retroviruses 27, no. 8 (August 2011): 889–901. https://doi.org/10.1089/AID.2010.0177.Full Text Link to Item
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Russell, Elizabeth S., Jesse J. Kwiek, Jessica Keys, Kirston Barton, Victor Mwapasa, David C. Montefiori, Steven R. Meshnick, and Ronald Swanstrom. “The genetic bottleneck in vertical transmission of subtype C HIV-1 is not driven by selection of especially neutralization-resistant virus from the maternal viral population.” J Virol 85, no. 16 (August 2011): 8253–62. https://doi.org/10.1128/JVI.00197-11.Full Text Link to Item
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Pollara, Justin, Lydia Hart, Faraha Brewer, Joy Pickeral, Beverly Z. Packard, James A. Hoxie, Akira Komoriya, et al. “High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses.” Cytometry A 79, no. 8 (August 2011): 603–12. https://doi.org/10.1002/cyto.a.21084.Full Text Link to Item
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Lai, Lilin, Suefen Kwa, Pamela A. Kozlowski, David C. Montefiori, Guido Ferrari, Welkin E. Johnson, Vanessa Hirsch, et al. “Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine.” J Infect Dis 204, no. 1 (July 1, 2011): 164–73. https://doi.org/10.1093/infdis/jir199.Full Text Link to Item
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Mörner, Andreas, Marianne Jansson, Evelien M. Bunnik, Jørgen Schøller, Robert Vaughan, Yufei Wang, David C. Montefiori, et al. “Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques.” J Virol 85, no. 13 (July 2011): 6442–52. https://doi.org/10.1128/JVI.00129-11.Full Text Link to Item
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Martin, Grégoire, Brian Burke, Robert Thaï, Antu K. Dey, Olivier Combes, Oscar H. P. Ramos, Bernadette Heyd, et al. “Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimetic.” J Biol Chem 286, no. 24 (June 17, 2011): 21706–16. https://doi.org/10.1074/jbc.M111.232272.Full Text Link to Item
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Schell, John B., Nina F. Rose, Kapil Bahl, Kathryn Diller, Linda Buonocore, Meredith Hunter, Preston A. Marx, et al. “Significant protection against high-dose simian immunodeficiency virus challenge conferred by a new prime-boost vaccine regimen.” J Virol 85, no. 12 (June 2011): 5764–72. https://doi.org/10.1128/JVI.00342-11.Full Text Link to Item
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Piehler, Britt, Elizabeth K. Nelson, Josh Eckels, Sarah Ramsay, Karl Lum, Blake Wood, Kelli M. Greene, et al. “LabKey Server NAb: a tool for analyzing, visualizing and sharing results from neutralizing antibody assays.” Bmc Immunol 12 (May 27, 2011): 33. https://doi.org/10.1186/1471-2172-12-33.Full Text Link to Item
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Letvin, Norman L., Srinivas S. Rao, David C. Montefiori, Michael S. Seaman, Yue Sun, So-Yon Lim, Wendy W. Yeh, et al. “Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys.” Sci Transl Med 3, no. 81 (May 4, 2011): 81ra36. https://doi.org/10.1126/scitranslmed.3002351.Full Text Link to Item
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Spearman, Paul, Michelle A. Lally, Marnie Elizaga, David Montefiori, Georgia D. Tomaras, M Juliana McElrath, John Hural, et al. “A trimeric, V2-deleted HIV-1 envelope glycoprotein vaccine elicits potent neutralizing antibodies but limited breadth of neutralization in human volunteers.” J Infect Dis 203, no. 8 (April 15, 2011): 1165–73. https://doi.org/10.1093/infdis/jiq175.Full Text Link to Item
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Siddappa, Nagadenahalli B., Girish Hemashettar, Yin Ling Wong, Samir Lakhashe, Robert A. Rasmussen, Jennifer D. Watkins, Francis J. Novembre, et al. “Development of a tier 1 R5 clade C simian-human immunodeficiency virus as a tool to test neutralizing antibody-based immunoprophylaxis.” J Med Primatol 40, no. 2 (April 2011): 120–28. https://doi.org/10.1111/j.1600-0684.2010.00454.x.Full Text Link to Item
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Jiang, Haixiang, Garren Hester, Larry Liao, David C. Montefiori, and Michael M. Frank. “Mechanisms by which HIV envelope minimizes immunogenicity.” Immunol Res 49, no. 1–3 (April 2011): 147–58. https://doi.org/10.1007/s12026-010-8178-6.Full Text Link to Item
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Manrique, Mariana, Pamela A. Kozlowski, Antonio Cobo-Molinos, Shainn-Wei Wang, Robert L. Wilson, David C. Montefiori, Keith G. Mansfield, Angela Carville, and Anna Aldovini. “Long-term control of simian immunodeficiency virus mac251 viremia to undetectable levels in half of infected female rhesus macaques nasally vaccinated with simian immunodeficiency virus DNA/recombinant modified vaccinia virus Ankara.” J Immunol 186, no. 6 (March 15, 2011): 3581–93. https://doi.org/10.4049/jimmunol.1002594.Full Text Link to Item
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Goepfert, Paul A., Marnie L. Elizaga, Alicia Sato, Li Qin, Massimo Cardinali, Christine M. Hay, John Hural, et al. “Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles.” J Infect Dis 203, no. 5 (March 1, 2011): 610–19. https://doi.org/10.1093/infdis/jiq105.Full Text Link to Item
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Patterson, L Jean, Mara Daltabuit-Test, Peng Xiao, Jun Zhao, William Hu, Ulrike Wille-Reece, Egidio Brocca-Cofano, et al. “Rapid SIV Env-specific mucosal and serum antibody induction augments cellular immunity in protecting immunized, elite-controller macaques against high dose heterologous SIV challenge.” Virology 411, no. 1 (March 1, 2011): 87–102. https://doi.org/10.1016/j.virol.2010.12.033.Full Text Link to Item
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Salazar-Gonzalez, Jesus F., Maria G. Salazar, Gerald H. Learn, Genevieve G. Fouda, Helen H. Kang, Tatenda Mahlokozera, Andrew B. Wilks, et al. “Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing.” J Virol 85, no. 6 (March 2011): 2751–63. https://doi.org/10.1128/JVI.02316-10.Full Text Open Access Copy Link to Item
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Keefer, Michael C., Sharon E. Frey, Marnie Elizaga, Barbara Metch, Stephen C. De Rosa, Paulo F. Barroso, Georgia Tomaras, et al. “A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects.” Vaccine 29, no. 10 (February 24, 2011): 1948–58. https://doi.org/10.1016/j.vaccine.2010.12.104.Full Text Link to Item
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Kirchherr, Jennifer L., Jennifer Hamilton, Xiaozhi Lu, S. Gnanakaran, Mark Muldoon, Marcus Daniels, Webster Kasongo, et al. “Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120.” Virology 409, no. 2 (January 20, 2011): 163–74. https://doi.org/10.1016/j.virol.2010.09.031.Full Text Link to Item
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Churchyard, Gavin J., Cecilia Morgan, Elizabeth Adams, John Hural, Barney S. Graham, Zoe Moodie, Doug Grove, et al. “A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204).” Plos One 6, no. 8 (2011): e21225. https://doi.org/10.1371/journal.pone.0021225.Full Text Link to Item
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Koblin, Beryl A., Martin Casapia, Cecilia Morgan, Li Qin, Zhixue Maggie Wang, Olivier D. Defawe, Lindsey Baden, et al. “Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial.” Plos One 6, no. 9 (2011): e24517. https://doi.org/10.1371/journal.pone.0024517.Full Text Link to Item
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Lakhashe, Samir K., Wendy Wang, Nagadenahalli B. Siddappa, Girish Hemashettar, Patricia Polacino, Shiu-Lok Hu, François Villinger, et al. “Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.” Plos One 6, no. 7 (2011): e22010. https://doi.org/10.1371/journal.pone.0022010.Full Text Link to Item
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Oballah, Peter, Britta Flach, Leigh A. Eller, Michael A. Eller, Benson Ouma, Mark de Souza, Hannah N. Kibuuka, et al. “B cell depletion in HIV-1 subtype A infected Ugandan adults: relationship to CD4 T cell count, viral load and humoral immune responses.” Plos One 6, no. 8 (2011): e22653. https://doi.org/10.1371/journal.pone.0022653.Full Text Link to Item
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Morris, Lynn, Xi Chen, Munir Alam, Georgia Tomaras, Ruijun Zhang, Dawn J. Marshall, Bing Chen, et al. “Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting.” Plos One 6, no. 9 (2011): e23532. https://doi.org/10.1371/journal.pone.0023532.Full Text Link to Item
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Kannanganat, Sunil, Pragati Nigam, Vijayakumar Velu, Patricia L. Earl, Lilin Lai, Lakshmi Chennareddi, Benton Lawson, et al. “Preexisting vaccinia virus immunity decreases SIV-specific cellular immunity but does not diminish humoral immunity and efficacy of a DNA/MVA vaccine.” J Immunol 185, no. 12 (December 15, 2010): 7262–73. https://doi.org/10.4049/jimmunol.1000751.Full Text Link to Item
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Vaine, Michael, Shixia Wang, Qin Liu, James Arthos, David Montefiori, Paul Goepfert, M Juliana McElrath, and Shan Lu. “Profiles of human serum antibody responses elicited by three leading HIV vaccines focusing on the induction of Env-specific antibodies.” Plos One 5, no. 11 (November 9, 2010): e13916. https://doi.org/10.1371/journal.pone.0013916.Full Text Open Access Copy Link to Item
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Dreja, Hanna, Eithne O’Sullivan, Corinna Pade, Kelli M. Greene, Hongmei Gao, Keith Aubin, James Hand, et al. “Neutralization activity in a geographically diverse East London cohort of human immunodeficiency virus type 1-infected patients: clade C infection results in a stronger and broader humoral immune response than clade B infection.” J Gen Virol 91, no. Pt 11 (November 2010): 2794–2803. https://doi.org/10.1099/vir.0.024224-0.Full Text Open Access Copy Link to Item
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Lai, Bonnie E., Anthony R. Geonnotti, Michael G. Desoto, David C. Montefiori, and David F. Katz. “Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro.” Antiviral Res 88, no. 2 (November 2010): 143–51. https://doi.org/10.1016/j.antiviral.2010.08.006.Full Text Link to Item
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Gnanakaran, S., Marcus G. Daniels, Tanmoy Bhattacharya, Alan S. Lapedes, Anurag Sethi, Ming Li, Haili Tang, et al. “Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.” Plos Comput Biol 6, no. 10 (October 7, 2010): e1000955. https://doi.org/10.1371/journal.pcbi.1000955.Full Text Open Access Copy Link to Item
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Mohr, Emma L., Jinhua Xiang, James H. McLinden, Thomas M. Kaufman, Qing Chang, David C. Montefiori, Donna Klinzman, and Jack T. Stapleton. “GB virus type C envelope protein E2 elicits antibodies that react with a cellular antigen on HIV-1 particles and neutralize diverse HIV-1 isolates.” J Immunol 185, no. 7 (October 1, 2010): 4496–4505. https://doi.org/10.4049/jimmunol.1001980.Full Text Link to Item
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Gegerfelt, Agneta von, Antonio Valentin, Candido Alicea, Koen K. A. Van Rompay, Marta L. Marthas, David C. Montefiori, George N. Pavlakis, and Barbara K. Felber. “Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus.” J Immunol 185, no. 6 (September 15, 2010): 3348–58. https://doi.org/10.4049/jimmunol.1000572.Full Text Link to Item
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Traina-Dorge, V., B. Pahar, P. Marx, P. Kissinger, D. Montefiori, Y. Ou, and W. L. Gray. “Recombinant varicella vaccines induce neutralizing antibodies and cellular immune responses to SIV and reduce viral loads in immunized rhesus macaques.” Vaccine 28, no. 39 (September 7, 2010): 6483–90. https://doi.org/10.1016/j.vaccine.2010.07.018.Full Text Link to Item
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Gilbert, Peter, Maggie Wang, Terri Wrin, Chris Petropoulos, Marc Gurwith, Faruk Sinangil, Patricia D’Souza, et al. “Magnitude and breadth of a nonprotective neutralizing antibody response in an efficacy trial of a candidate HIV-1 gp120 vaccine.” J Infect Dis 202, no. 4 (August 15, 2010): 595–605. https://doi.org/10.1086/654816.Full Text Open Access Copy Link to Item
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Smith, Douglas H., Peggy Winters-Digiacinto, Misrach Mitiku, Sara O’Rourke, Faruk Sinangil, Terri Wrin, David C. Montefiori, and Phillip W. Berman. “Comparative immunogenicity of HIV-1 clade C envelope proteins for prime/boost studies.” Plos One 5, no. 8 (August 11, 2010): e12076. https://doi.org/10.1371/journal.pone.0012076.Full Text Open Access Copy Link to Item
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Graham, Barney S., M Juliana McElrath, Michael C. Keefer, Kyle Rybczyk, David Berger, Kent J. Weinhold, Janet Ottinger, et al. “Immunization with cocktail of HIV-derived peptides in montanide ISA-51 is immunogenic, but causes sterile abscesses and unacceptable reactogenicity.” Plos One 5, no. 8 (August 10, 2010): e11995. https://doi.org/10.1371/journal.pone.0011995.Full Text Open Access Copy Link to Item
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Siddappa, Nagadenahalli B., Jennifer D. Watkins, Klemens J. Wassermann, Ruijiang Song, Wendy Wang, Victor G. Kramer, Samir Lakhashe, et al. “R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models.” Plos One 5, no. 7 (July 21, 2010): e11689. https://doi.org/10.1371/journal.pone.0011689.Full Text Open Access Copy Link to Item
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Matoba, Nobuyuki, Adam S. Husk, Brian W. Barnett, Michelle M. Pickel, Charles J. Arntzen, David C. Montefiori, Atsushi Takahashi, et al. “HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity.” Plos One 5, no. 6 (June 15, 2010): e11143. https://doi.org/10.1371/journal.pone.0011143.Full Text Open Access Copy Link to Item
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Bianchi, Elisabetta, Joseph G. Joyce, Michael D. Miller, Adam C. Finnefrock, Xiaoping Liang, Marco Finotto, Paolo Ingallinella, et al. “Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates.” Proc Natl Acad Sci U S A 107, no. 23 (June 8, 2010): 10655–60. https://doi.org/10.1073/pnas.1004261107.Full Text Link to Item
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Zahn, Roland C., Melisa D. Rett, Ming Li, Haili Tang, Birgit Korioth-Schmitz, Harikrishnan Balachandran, Robert White, et al. “Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease.” Blood 115, no. 15 (April 15, 2010): 3070–78. https://doi.org/10.1182/blood-2009-10-245225.Full Text Link to Item
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Moody, M Anthony, Hua-Xin Liao, S Munir Alam, Richard M. Scearce, M Kelly Plonk, Daniel M. Kozink, Mark S. Drinker, et al. “Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines.” J Exp Med 207, no. 4 (April 12, 2010): 763–76. https://doi.org/10.1084/jem.20091281.Full Text Open Access Copy Link to Item
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Nkolola, Joseph P., Hanqin Peng, Ethan C. Settembre, Michael Freeman, Lauren E. Grandpre, Colleen Devoy, Diana M. Lynch, et al. “Breadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigs.” J Virol 84, no. 7 (April 2010): 3270–79. https://doi.org/10.1128/JVI.02252-09.Full Text Link to Item
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Robinson, James E., Kelly Franco, Debra Holton Elliott, Mary Jane Maher, Ashley Reyna, David C. Montefiori, Susan Zolla-Pazner, Miroslaw K. Gorny, Zane Kraft, and Leonidas Stamatatos. “Quaternary epitope specificities of anti-HIV-1 neutralizing antibodies generated in rhesus macaques infected by the simian/human immunodeficiency virus SHIVSF162P4.” J Virol 84, no. 7 (April 2010): 3443–53. https://doi.org/10.1128/JVI.02617-09.Full Text Link to Item
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Shen, Xiaoying, S Moses Dennison, Pinghuang Liu, Feng Gao, Frederick Jaeger, David C. Montefiori, Laurent Verkoczy, Barton F. Haynes, S Munir Alam, and Georgia D. Tomaras. “Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution.” Proc Natl Acad Sci U S A 107, no. 13 (March 30, 2010): 5972–77. https://doi.org/10.1073/pnas.0912381107.Full Text Link to Item
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Geonnotti, Anthony R., Miroslawa Bilska, Xing Yuan, Christina Ochsenbauer, Tara G. Edmonds, John C. Kappes, Hua-Xin Liao, Barton F. Haynes, and David C. Montefiori. “Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma interferon production.” Aids Res Hum Retroviruses 26, no. 3 (March 2010): 279–91. https://doi.org/10.1089/aid.2009.0186.Full Text Open Access Copy Link to Item
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Seaman, Michael S., Holly Janes, Natalie Hawkins, Lauren E. Grandpre, Colleen Devoy, Ayush Giri, Rory T. Coffey, et al. “Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies.” J Virol 84, no. 3 (February 2010): 1439–52. https://doi.org/10.1128/JVI.02108-09.Full Text Link to Item
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Corti, Davide, Johannes P. M. Langedijk, Andreas Hinz, Michael S. Seaman, Fabrizia Vanzetta, Blanca M. Fernandez-Rodriguez, Chiara Silacci, et al. “Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.” Plos One 5, no. 1 (January 20, 2010): e8805. https://doi.org/10.1371/journal.pone.0008805.Full Text Open Access Copy Link to Item
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Nandi, Avishek, Christine L. Lavine, Pengcheng Wang, Inna Lipchina, Paul A. Goepfert, George M. Shaw, Georgia D. Tomaras, et al. “Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1.” Virology 396, no. 2 (January 20, 2010): 339–48. https://doi.org/10.1016/j.virol.2009.10.044.Full Text Link to Item
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Mascola, John R., and David C. Montefiori. “The role of antibodies in HIV vaccines.” Annu Rev Immunol 28 (2010): 413–44. https://doi.org/10.1146/annurev-immunol-030409-101256.Full Text Link to Item
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Zhang, Mei-Yun, Andrew Rosa Borges, Roger G. Ptak, Yanping Wang, Antony S. Dimitrov, S Munir Alam, Lindsay Wieczorek, et al. “Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1.” Mabs 2, no. 3 (2010): 266–74. https://doi.org/10.4161/mabs.2.3.11416.Full Text Open Access Copy Link to Item
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Faul, Elizabeth J., Pyone P. Aye, Amy B. Papaneri, Bapi Pahar, James P. McGettigan, Faith Schiro, Inna Chervoneva, David C. Montefiori, Andrew A. Lackner, and Matthias J. Schnell. “Rabies virus-based vaccines elicit neutralizing antibodies, poly-functional CD8+ T cell, and protect rhesus macaques from AIDS-like disease after SIV(mac251) challenge.” Vaccine 28, no. 2 (December 11, 2009): 299–308. https://doi.org/10.1016/j.vaccine.2009.10.051.Full Text Link to Item
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Schmitz, Jörn E., Roland C. Zahn, Charles R. Brown, Melisa D. Rett, Ming Li, Haili Tang, Sarah Pryputniewicz, et al. “Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys.” Plos Pathog 5, no. 12 (December 2009): e1000691. https://doi.org/10.1371/journal.ppat.1000691.Full Text Open Access Copy Link to Item
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Weaver, Eric A., Pramod N. Nehete, Bharti P. Nehete, Stephanie J. Buchl, Donna Palmer, David C. Montefiori, Philip Ng, K Jagannadha Sastry, and Michael A. Barry. “Protection against Mucosal SHIV Challenge by Peptide and Helper-Dependent Adenovirus Vaccines.” Viruses 1, no. 3 (December 1, 2009): 920. https://doi.org/10.3390/v1030920.Full Text Link to Item
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Manrique, M., P. A. Kozlowski, S. -. W. Wang, R. L. Wilson, E. Micewicz, D. C. Montefiori, K. G. Mansfield, A. Carville, and A. Aldovini. “Nasal DNA-MVA SIV vaccination provides more significant protection from progression to AIDS than a similar intramuscular vaccination.” Mucosal Immunol 2, no. 6 (November 2009): 536–50. https://doi.org/10.1038/mi.2009.103.Full Text Link to Item
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Del Prete, Gregory Q., Beth Haggarty, George J. Leslie, Andrea P. O. Jordan, Josephine Romano, Nathaniel Wang, Jianbin Wang, Michael C. Holmes, David C. Montefiori, and James A. Hoxie. “Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4.” J Virol 83, no. 19 (October 2009): 9911–22. https://doi.org/10.1128/JVI.00533-09.Full Text Link to Item
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Gaufin, Thaidra, Melissa Pattison, Rajeev Gautam, Crystal Stoulig, Jason Dufour, Jeanne MacFarland, Daniel Mandell, et al. “Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural host.” J Virol 83, no. 20 (October 2009): 10347–57. https://doi.org/10.1128/JVI.00880-09.Full Text Link to Item
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Santra, Sampa, Yue Sun, Birgit Korioth-Schmitz, Julie Fitzgerald, Cherie Charbonneau, Giannina Santos, Michael S. Seaman, et al. “Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors.” Vaccine 27, no. 42 (September 25, 2009): 5837–45. https://doi.org/10.1016/j.vaccine.2009.07.050.Full Text Link to Item
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Rosati, Margherita, Cristina Bergamaschi, Antonio Valentin, Viraj Kulkarni, Rashmi Jalah, Candido Alicea, Vainav Patel, et al. “DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge.” Proc Natl Acad Sci U S A 106, no. 37 (September 15, 2009): 15831–36. https://doi.org/10.1073/pnas.0902628106.Full Text Link to Item
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Barouch, Dan H., Jinyan Liu, Diana M. Lynch, Kara L. O’Brien, Annalena La Porte, Nathaniel L. Simmons, Ambryice M. Riggs, et al. “Protective efficacy of a single immunization of a chimeric adenovirus vector-based vaccine against simian immunodeficiency virus challenge in rhesus monkeys.” J Virol 83, no. 18 (September 2009): 9584–90. https://doi.org/10.1128/JVI.00821-09.Full Text Link to Item
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Gray, Elin S., Natasha Taylor, Diane Wycuff, Penny L. Moore, Georgia D. Tomaras, Constantinos Kurt Wibmer, Adrian Puren, et al. “Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors.” J Virol 83, no. 17 (September 2009): 8925–37. https://doi.org/10.1128/JVI.00758-09.Full Text Link to Item
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Meyuhas, Ronit, Hava Noy, Sigal Fishman, Alon Margalit, David C. Montefiori, and Gideon Gross. “Enhanced HIV-1 neutralization by a CD4-VH3-IgG1 fusion protein.” Biochem Biophys Res Commun 386, no. 2 (August 21, 2009): 402–6. https://doi.org/10.1016/j.bbrc.2009.06.057.Full Text Link to Item
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Hinz, Andreas, Guy Schoehn, Heribert Quendler, David Lutje Hulsik, Gabi Stiegler, Hermann Katinger, Michael S. Seaman, David Montefiori, and Winfried Weissenhorn. “Characterization of a trimeric MPER containing HIV-1 gp41 antigen.” Virology 390, no. 2 (August 1, 2009): 221–27. https://doi.org/10.1016/j.virol.2009.05.015.Full Text Link to Item
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Perez, Lautaro G., Matthew R. Costa, Christopher A. Todd, Barton F. Haynes, and David C. Montefiori. “Utilization of immunoglobulin G Fc receptors by human immunodeficiency virus type 1: a specific role for antibodies against the membrane-proximal external region of gp41.” J Virol 83, no. 15 (August 2009): 7397–7410. https://doi.org/10.1128/JVI.00656-09.Full Text Link to Item
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Platt, Emily J., Miroslawa Bilska, Susan L. Kozak, David Kabat, and David C. Montefiori. “Evidence that ecotropic murine leukemia virus contamination in TZM-bl cells does not affect the outcome of neutralizing antibody assays with human immunodeficiency virus type 1.” J Virol 83, no. 16 (August 2009): 8289–92. https://doi.org/10.1128/JVI.00709-09.Full Text Link to Item
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Lambotte, Olivier, Guido Ferrari, Christiane Moog, Nicole L. Yates, Hua-Xin Liao, Robert J. Parks, Charles B. Hicks, et al. “Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers.” Aids 23, no. 8 (May 15, 2009): 897–906. https://doi.org/10.1097/QAD.0b013e328329f97d.Full Text Link to Item
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Davis, Katie L., Elin S. Gray, Penny L. Moore, Julie M. Decker, Aidy Salomon, David C. Montefiori, Barney S. Graham, et al. “High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination.” Virology 387, no. 2 (May 10, 2009): 414–26. https://doi.org/10.1016/j.virol.2009.02.022.Full Text Link to Item
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Pahar, Bapi, Andrew A. Lackner, Michael Piatak, Jeffrey D. Lifson, Xiaolei Wang, Arpita Das, Binhua Ling, David C. Montefiori, and Ronald S. Veazey. “Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge.” Virology 387, no. 2 (May 10, 2009): 273–84. https://doi.org/10.1016/j.virol.2009.02.014.Full Text Link to Item
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Zhao, Jun, Lilin Lai, Rama Rao Amara, David C. Montefiori, Francois Villinger, Lakshmi Chennareddi, Linda S. Wyatt, Bernard Moss, and Harriet L. Robinson. “Preclinical studies of human immunodeficiency virus/AIDS vaccines: inverse correlation between avidity of anti-Env antibodies and peak postchallenge viremia.” J Virol 83, no. 9 (May 2009): 4102–11. https://doi.org/10.1128/JVI.02173-08.Full Text Link to Item
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Gaufin, Thaidra, Rajeev Gautam, Melissa Kasheta, Ruy Ribeiro, Erin Ribka, Mary Barnes, Melissa Pattison, et al. “Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain.” Blood 113, no. 18 (April 30, 2009): 4250–61. https://doi.org/10.1182/blood-2008-09-177741.Full Text Link to Item
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O’Keefe, Barry R., Fakhrieh Vojdani, Viviana Buffa, Robin J. Shattock, David C. Montefiori, James Bakke, Jon Mirsalis, et al. “Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component.” Proc Natl Acad Sci U S A 106, no. 15 (April 14, 2009): 6099–6104. https://doi.org/10.1073/pnas.0901506106.Full Text Link to Item
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Ma, Zhong-Min, Mars Stone, Mike Piatak, Becky Schweighardt, Nancy L. Haigwood, David Montefiori, Jeffrey D. Lifson, Michael P. Busch, and Christopher J. Miller. “High specific infectivity of plasma virus from the pre-ramp-up and ramp-up stages of acute simian immunodeficiency virus infection.” J Virol 83, no. 7 (April 2009): 3288–97. https://doi.org/10.1128/JVI.02423-08.Full Text Link to Item
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Shen, Xiaoying, Robert J. Parks, David C. Montefiori, Jennifer L. Kirchherr, Brandon F. Keele, Julie M. Decker, William A. Blattner, et al. “In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth.” J Virol 83, no. 8 (April 2009): 3617–25. https://doi.org/10.1128/JVI.02631-08.Full Text Link to Item
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Kulkarni, Smita S., Alan Lapedes, Haili Tang, S. Gnanakaran, Marcus G. Daniels, Ming Zhang, Tanmoy Bhattacharya, et al. “Highly complex neutralization determinants on a monophyletic lineage of newly transmitted subtype C HIV-1 Env clones from India.” Virology 385, no. 2 (March 15, 2009): 505–20. https://doi.org/10.1016/j.virol.2008.12.032.Full Text Link to Item
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Yeh, Wendy W., Pimkwan Jaru-Ampornpan, Daiva Nevidomskyte, Mohammed Asmal, Srinivas S. Rao, Adam P. Buzby, David C. Montefiori, Bette T. Korber, and Norman L. Letvin. “Partial protection of Simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate.” J Virol 83, no. 6 (March 2009): 2686–96. https://doi.org/10.1128/JVI.02237-08.Full Text Link to Item
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Fenyö, E. M., A. Heath, S. Dispinseri, H. Holmes, P. Lusso, S. Zolla-Pazner, H. Donners, et al. “International network for comparison of HIV neutralization assays: The NeutNet report.” Plos One 4, no. 2 (February 20, 2009). https://doi.org/10.1371/journal.pone.0004505.Full Text
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Schell, John, Nina F. Rose, Nicole Fazo, Preston A. Marx, Meredith Hunter, Elizabeth Ramsburg, David Montefiori, Patricia Earl, Bernard Moss, and John K. Rose. “Long-term vaccine protection from AIDS and clearance of viral DNA following SHIV89.6P challenge.” Vaccine 27, no. 7 (February 11, 2009): 979–86. https://doi.org/10.1016/j.vaccine.2008.12.017.Full Text Link to Item
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Huang, Yunda, Peter B. Gilbert, David C. Montefiori, and Steve G. Self. “Simultaneous Evaluation of the Magnitude and Breadth of a Left and Right Censored Multivariate Response, with Application to HIV Vaccine Development.” Stat Biopharm Res 1, no. 1 (February 1, 2009): 81–91. https://doi.org/10.1198/sbr.2009.0008.Full Text Link to Item
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Siddappa, Nagadenahalli B., Ruijiang Song, Victor G. Kramer, Agnès-Laurence Chenine, Vijayakumar Velu, Helena Ong, Robert A. Rasmussen, et al. “Neutralization-sensitive R5-tropic simian-human immunodeficiency virus SHIV-2873Nip, which carries env isolated from an infant with a recent HIV clade C infection.” J Virol 83, no. 3 (February 2009): 1422–32. https://doi.org/10.1128/JVI.02066-08.Full Text Link to Item
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Hidajat, Rachmat, Peng Xiao, Qifeng Zhou, David Venzon, L Ebonita Summers, Vaniambadi S. Kalyanaraman, David C. Montefiori, and Marjorie Robert-Guroff. “Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques.” J Virol 83, no. 2 (January 2009): 791–801. https://doi.org/10.1128/JVI.01672-08.Full Text Link to Item
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Liu, Jinyan, Kara L. O’Brien, Diana M. Lynch, Nathaniel L. Simmons, Annalena La Porte, Ambryice M. Riggs, Peter Abbink, et al. “Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys.” Nature 457, no. 7225 (January 1, 2009): 87–91. https://doi.org/10.1038/nature07469.Full Text Link to Item
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Montefiori, David C. “Measuring HIV neutralization in a luciferase reporter gene assay.” Methods Mol Biol 485 (2009): 395–405. https://doi.org/10.1007/978-1-59745-170-3_26.Full Text Link to Item
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Tomaras, Georgia D., Nicole L. Yates, Pinghuang Liu, Li Qin, Genevieve G. Fouda, Leslie L. Chavez, Allan C. Decamp, et al. “Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia.” J Virol 82, no. 24 (December 2008): 12449–63. https://doi.org/10.1128/JVI.01708-08.Full Text Link to Item
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Binley, James M., Elizabeth A. Lybarger, Emma T. Crooks, Michael S. Seaman, Elin Gray, Katie L. Davis, Julie M. Decker, et al. “Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.” J Virol 82, no. 23 (December 2008): 11651–68. https://doi.org/10.1128/JVI.01762-08.Full Text Link to Item
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Morgan, Cecilia, Marta Marthas, Christopher Miller, Ann Duerr, Cecilia Cheng-Mayer, Ronald Desrosiers, Jorge Flores, et al. “The use of nonhuman primate models in HIV vaccine development.” Plos Med 5, no. 8 (August 12, 2008): e173. https://doi.org/10.1371/journal.pmed.0050173.Full Text Link to Item
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Vaine, Michael, Shixia Wang, Emma T. Crooks, Pengfei Jiang, David C. Montefiori, James Binley, and Shan Lu. “Improved induction of antibodies against key neutralizing epitopes by human immunodeficiency virus type 1 gp120 DNA prime-protein boost vaccination compared to gp120 protein-only vaccination.” J Virol 82, no. 15 (August 2008): 7369–78. https://doi.org/10.1128/JVI.00562-08.Full Text Link to Item
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Luallen, Robert J., Jianqiao Lin, Hu Fu, Karen K. Cai, Caroline Agrawal, Innocent Mboudjeka, Fang-Hua Lee, et al. “An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies.” J Virol 82, no. 13 (July 2008): 6447–57. https://doi.org/10.1128/JVI.00412-08.Full Text Link to Item
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Zhang, Mei-Yun, Bang K. Vu, Anil Choudhary, Hong Lu, Michael Humbert, Helena Ong, Munir Alam, et al. “Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens.” J Virol 82, no. 14 (July 2008): 6869–79. https://doi.org/10.1128/JVI.00033-08.Full Text Link to Item
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Polonis, Victoria R., Bruce K. Brown, Andrew Rosa Borges, Susan Zolla-Pazner, Dimiter S. Dimitrov, Mei-Yun Zhang, Susan W. Barnett, et al. “Recent advances in the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination.” Virology 375, no. 2 (June 5, 2008): 315–20. https://doi.org/10.1016/j.virol.2008.02.007.Full Text Link to Item
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Veazey, Ronald S., Paula M. Acierno, Kimberly J. McEvers, Susanne H. C. Baumeister, Gabriel J. Foster, Melisa D. Rett, Michael H. Newberg, et al. “Increased loss of CCR5+ CD45RA- CD4+ T cells in CD8+ lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeys.” J Virol 82, no. 11 (June 2008): 5618–30. https://doi.org/10.1128/JVI.02748-07.Full Text Link to Item
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Keele, Brandon F., Elena E. Giorgi, Jesus F. Salazar-Gonzalez, Julie M. Decker, Kimmy T. Pham, Maria G. Salazar, Chuanxi Sun, et al. “Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.” Proc Natl Acad Sci U S A 105, no. 21 (May 27, 2008): 7552–57. https://doi.org/10.1073/pnas.0802203105.Full Text Link to Item
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Patterson, L Jean, Jennifer Beal, Thorsten Demberg, Ruth H. Florese, Nina Malkevich, David Venzon, Kris Aldrich, et al. “Replicating adenovirus HIV/SIV recombinant priming alone or in combination with a gp140 protein boost results in significant control of viremia following a SHIV89.6P challenge in Mamu-A*01 negative rhesus macaques.” Virology 374, no. 2 (May 10, 2008): 322–37. https://doi.org/10.1016/j.virol.2007.12.037.Full Text Link to Item
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Matoba, Nobuyuki, Tagan A. Griffin, Michele Mittman, Jeffrey D. Doran, Annette Alfsen, David C. Montefiori, Carl V. Hanson, Morgane Bomsel, and Tsafrir S. Mor. “Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes.” Curr Hiv Res 6, no. 3 (May 2008): 218–29. https://doi.org/10.2174/157016208784324994.Full Text Link to Item
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Juompan, Laure Y., Karen Hutchinson, David C. Montefiori, Soumya Nidtha, François Villinger, and Francis J. Novembre. “Analysis of the immune responses in chimpanzees infected with HIV type 1 isolates.” Aids Res Hum Retroviruses 24, no. 4 (April 2008): 573–86. https://doi.org/10.1089/aid.2007.0182.Full Text Link to Item
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Penn-Nicholson, Adam, Dong P. Han, Soon J. Kim, Hanna Park, Rais Ansari, David C. Montefiori, and Michael W. Cho. “Assessment of antibody responses against gp41 in HIV-1-infected patients using soluble gp41 fusion proteins and peptides derived from M group consensus envelope.” Virology 372, no. 2 (March 15, 2008): 442–56. https://doi.org/10.1016/j.virol.2007.11.009.Full Text Link to Item
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Manrique, Mariana, Ewa Micewicz, Pamela A. Kozlowski, Shainn-Wei Wang, Deepti Aurora, Robert L. Wilson, Musie Ghebremichael, et al. “DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory.” Aids Res Hum Retroviruses 24, no. 3 (March 2008): 505–19. https://doi.org/10.1089/aid.2007.0191.Full Text Link to Item
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Wang, Shixia, Jeffrey S. Kennedy, Kim West, David C. Montefiori, Scott Coley, John Lawrence, Siyuan Shen, et al. “Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.” Vaccine 26, no. 8 (February 20, 2008): 1098–1110. https://doi.org/10.1016/j.vaccine.2007.12.024.Full Text Link to Item
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Bielinska, Anna U., Katarzyna W. Janczak, Jeffrey J. Landers, David M. Markovitz, David C. Montefiori, and James R. Baker. “Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates.” Aids Res Hum Retroviruses 24, no. 2 (February 2008): 271–81. https://doi.org/10.1089/aid.2007.0148.Full Text Link to Item
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Barnett, Susan W., Indresh K. Srivastava, Elaine Kan, Fengmin Zhou, Amanda Goodsell, Anthony D. Cristillo, Maria Grazia Ferrai, et al. “Protection of macaques against vaginal SHIV challenge by systemic or mucosal and systemic vaccinations with HIV-envelope.” Aids 22, no. 3 (January 30, 2008): 339–48. https://doi.org/10.1097/QAD.0b013e3282f3ca57.Full Text Link to Item
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Alam, S Munir, Richard M. Scearce, Robert J. Parks, Kelly Plonk, Steven G. Plonk, Laura L. Sutherland, Miroslaw K. Gorny, et al. “Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection.” J Virol 82, no. 1 (January 2008): 115–25. https://doi.org/10.1128/JVI.00927-07.Full Text Link to Item
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Lai, Weihong, Li Huang, Phong Ho, Zhijun Li, David Montefiori, and Chin-Ho Chen. “Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.” Antimicrob Agents Chemother 52, no. 1 (January 2008): 128–36. https://doi.org/10.1128/AAC.00737-07.Full Text Link to Item
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Li, Yun, Bradley Cleveland, Igor Klots, Bruce Travis, Barbra A. Richardson, David Anderson, David Montefiori, Patricia Polacino, and Shiu-Lok Hu. “Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses.” J Virol 82, no. 2 (January 2008): 638–51. https://doi.org/10.1128/JVI.01691-07.Full Text Link to Item
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Lai, Lilin, Dalma Vödrös, Pamela A. Kozlowski, David C. Montefiori, Robert L. Wilson, Vicki L. Akerstrom, Lakshmi Chennareddi, et al. “GM-CSF DNA: an adjuvant for higher avidity IgG, rectal IgA, and increased protection against the acute phase of a SHIV-89.6P challenge by a DNA/MVA immunodeficiency virus vaccine.” Virology 369, no. 1 (December 5, 2007): 153–67. https://doi.org/10.1016/j.virol.2007.07.017.Full Text Link to Item
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Ljungberg, Karl, Alan C. Whitmore, Meagan E. Fluet, Timothy P. Moran, Reed S. Shabman, Martha L. Collier, Annette A. Kraus, et al. “Increased immunogenicity of a DNA-launched Venezuelan equine encephalitis virus-based replicon DNA vaccine.” J Virol 81, no. 24 (December 2007): 13412–23. https://doi.org/10.1128/JVI.01799-07.Full Text Link to Item
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Robinson, Harriet L., Sunita Sharma, Jun Zhao, Sunil Kannanganat, Lilin Lai, Lakshmi Chennareddi, Tianwei Yu, et al. “Immunogenicity in macaques of the clinical product for a clade B DNA/MVA HIV vaccine: elicitation of IFN-gamma, IL-2, and TNF-alpha coproducing CD4 and CD8 T cells.” Aids Res Hum Retroviruses 23, no. 12 (December 2007): 1555–62. https://doi.org/10.1089/aid.2007.0165.Full Text Link to Item
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Seaman, Michael S., Daniel F. Leblanc, Lauren E. Grandpre, Melissa T. Bartman, David C. Montefiori, Norman L. Letvin, and John R. Mascola. “Standardized assessment of NAb responses elicited in rhesus monkeys immunized with single- or multi-clade HIV-1 envelope immunogens.” Virology 367, no. 1 (October 10, 2007): 175–86. https://doi.org/10.1016/j.virol.2007.05.024.Full Text Link to Item
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Cleghorn, Farley, Jean W. Pape, Mauro Schechter, Courtenay Bartholomew, Jorge Sanchez, Noreen Jack, Barbara J. Metch, et al. “Lessons from a multisite international trial in the Caribbean and South America of an HIV-1 Canarypox vaccine (ALVAC-HIV vCP1452) with or without boosting with MN rgp120.” J Acquir Immune Defic Syndr 46, no. 2 (October 1, 2007): 222–30. https://doi.org/10.1097/QAI.0b013e318149297d.Full Text Link to Item
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Crooks, Emma T., Penny L. Moore, Michael Franti, Charmagne S. Cayanan, Ping Zhu, Pengfei Jiang, Robbert P. de Vries, et al. “A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.” Virology 366, no. 2 (September 30, 2007): 245–62. https://doi.org/10.1016/j.virol.2007.04.033.Full Text Link to Item
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Earl, Patricia L., Jeffrey L. Americo, Linda S. Wyatt, Leigh Anne Eller, David C. Montefiori, Russ Byrum, Michael Piatak, et al. “Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate.” Virology 366, no. 1 (September 15, 2007): 84–97. https://doi.org/10.1016/j.virol.2007.02.041.Full Text Link to Item
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Santra, Sampa, Yue Sun, Jenny G. Parvani, Valerie Philippon, Michael S. Wyand, Kelledy Manson, Alicia Gomez-Yafal, et al. “Heterologous prime/boost immunization of rhesus monkeys by using diverse poxvirus vectors.” J Virol 81, no. 16 (August 2007): 8563–70. https://doi.org/10.1128/JVI.00744-07.Full Text Link to Item
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Kirchherr, Jennifer L., Xiaozhi Lu, Webster Kasongo, Victor Chalwe, Lawrence Mwananyanda, Rosemary M. Musonda, Shi-Mao Xia, et al. “High throughput functional analysis of HIV-1 env genes without cloning.” J Virol Methods 143, no. 1 (July 2007): 104–11. https://doi.org/10.1016/j.jviromet.2007.02.015.Full Text Link to Item
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Kim, Mikyung, Zhisong Qiao, Jessica Yu, David Montefiori, and Ellis L. Reinherz. “Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion state.” Vaccine 25, no. 27 (June 28, 2007): 5102–14. https://doi.org/10.1016/j.vaccine.2006.09.071.Full Text Link to Item
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Chong, Siew-Yen, Michael A. Egan, Michele A. Kutzler, Shakuntala Megati, Amjed Masood, Vidia Roopchard, Dorys Garcia-Hand, et al. “Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV(89.6P) challenge in rhesus macaques.” Vaccine 25, no. 26 (June 21, 2007): 4967–82. https://doi.org/10.1016/j.vaccine.2006.11.070.Full Text Link to Item
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Choudhry, Vidita, Mei-Yun Zhang, Igor A. Sidorov, John M. Louis, Ilia Harris, Antony S. Dimitrov, Peter Bouma, et al. “Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies.” Virology 363, no. 1 (June 20, 2007): 79–90. https://doi.org/10.1016/j.virol.2007.01.015.Full Text Link to Item
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Luckay, Amara, Maninder K. Sidhu, Rune Kjeken, Shakuntala Megati, Siew-Yen Chong, Vidia Roopchand, Dorys Garcia-Hand, et al. “Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques.” J Virol 81, no. 10 (May 2007): 5257–69. https://doi.org/10.1128/JVI.00055-07.Full Text Link to Item
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Miller, Christopher J., Meritxell Genescà, Kristina Abel, David Montefiori, Donald Forthal, Kristen Bost, Jun Li, David Favre, and Joseph M. McCune. “Antiviral antibodies are necessary for control of simian immunodeficiency virus replication.” J Virol 81, no. 10 (May 2007): 5024–35. https://doi.org/10.1128/JVI.02444-06.Full Text Link to Item
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Montefiori, David C., Lynn Morris, Guido Ferrari, and John R. Mascola. “Neutralizing and other antiviral antibodies in HIV-1 infection and vaccination.” Curr Opin Hiv Aids 2, no. 3 (May 2007): 169–76. https://doi.org/10.1097/COH.0b013e3280ef691e.Full Text Link to Item
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Demberg, Thorsten, Ruth H. Florese, Megan J. Heath, Kay Larsen, Irene Kalisz, V. S. Kalyanaraman, Eun Mi Lee, et al. “A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques.” J Virol 81, no. 7 (April 2007): 3414–27. https://doi.org/10.1128/JVI.02453-06.Full Text Link to Item
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McKenna, Philip M., Martin L. Koser, Kevin R. Carlson, David C. Montefiori, Norman L. Letvin, Amy B. Papaneri, Roger J. Pomerantz, et al. “Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rhesus macaques and protect from an AIDS-like disease.” J Infect Dis 195, no. 7 (April 1, 2007): 980–88. https://doi.org/10.1086/512243.Full Text Link to Item
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Pahar, Bapi, Michael Piatak, Xiaolei Wang, Jeffrey Lifson, David C. Montefiori, Binhua Ling, Andrew Lackner, and Ronald Veazey. “Control of viremia and preservation of intestinal CD4+T cells in SHIVsf162P3 infected macaques intravenously challenged with pathogenic SIVmac251.” Journal of Immunology 178 (April 1, 2007).Link to Item
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Ferrantelli, Flavia, Kathleen A. Buckley, Robert A. Rasmussen, Alistair Chalmers, Tao Wang, Pei-Lin Li, Alison L. Williams, et al. “Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaques.” Virology 358, no. 1 (February 5, 2007): 69–78. https://doi.org/10.1016/j.virol.2006.07.056.Full Text Link to Item
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Russell, Nina D., Barney S. Graham, Michael C. Keefer, M Juliana McElrath, Steve G. Self, Kent J. Weinhold, David C. Montefiori, et al. “Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.” J Acquir Immune Defic Syndr 44, no. 2 (February 1, 2007): 203–12. https://doi.org/10.1097/01.qai.0000248356.48501.ff.Full Text Link to Item
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Goepfert, Paul A., Georgia D. Tomaras, Helen Horton, David Montefiori, Guido Ferrari, Mark Deers, Gerald Voss, et al. “Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers.” Vaccine 25, no. 3 (January 5, 2007): 510–18. https://doi.org/10.1016/j.vaccine.2006.07.050.Full Text Link to Item
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Li, Ming, Jesus F. Salazar-Gonzalez, Cynthia A. Derdeyn, Lynn Morris, Carolyn Williamson, James E. Robinson, Julie M. Decker, et al. “Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa.” J Virol 80, no. 23 (December 2006): 11776–90. https://doi.org/10.1128/JVI.01730-06.Full Text Link to Item
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Pahar, Bapi, Mayra A. Cantu, Wei Zhao, Marcelo J. Kuroda, Ronald S. Veazey, David C. Montefiori, John D. Clements, et al. “Single epitope mucosal vaccine delivered via immuno-stimulating complexes induces low level of immunity against simian-HIV.” Vaccine 24, no. 47–48 (November 17, 2006): 6839–49. https://doi.org/10.1016/j.vaccine.2006.06.050.Full Text Link to Item
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Gómez-Román, V Raúl, Ruth H. Florese, Bo Peng, David C. Montefiori, Vaniambadi S. Kalyanaraman, David Venzon, Indresh Srivastava, Susan W. Barnett, and Marjorie Robert-Guroff. “An adenovirus-based HIV subtype B prime/boost vaccine regimen elicits antibodies mediating broad antibody-dependent cellular cytotoxicity against non-subtype B HIV strains.” J Acquir Immune Defic Syndr 43, no. 3 (November 1, 2006): 270–77. https://doi.org/10.1097/01.qai.0000230318.40170.60.Full Text Link to Item
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Liao, Hua-Xin, Laura L. Sutherland, Shi-Mao Xia, Mary E. Brock, Richard M. Scearce, Stacie Vanleeuwen, S Munir Alam, et al. “A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses.” Virology 353, no. 2 (September 30, 2006): 268–82. https://doi.org/10.1016/j.virol.2006.04.043.Full Text Link to Item
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Robinson, Harriet L., David C. Montefiori, Francois Villinger, James E. Robinson, Sunita Sharma, Linda S. Wyatt, Patricia L. Earl, Harold M. McClure, Bernard Moss, and Rama Rao Amara. “Studies on GM-CSF DNA as an adjuvant for neutralizing Ab elicited by a DNA/MVA immunodeficiency virus vaccine.” Virology 352, no. 2 (September 1, 2006): 285–94. https://doi.org/10.1016/j.virol.2006.02.011.Full Text Link to Item
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Haynes, Barton F., and David C. Montefiori. “Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates.” Expert Rev Vaccines 5, no. 4 (August 2006): 579–95. https://doi.org/10.1586/14760584.5.4.579.Full Text Link to Item
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Gray, Elin Solomonovna, Tammy Meyers, Glenda Gray, David Charles Montefiori, and Lynn Morris. “Insensitivity of paediatric HIV-1 subtype C viruses to broadly neutralising monoclonal antibodies raised against subtype B.” Plos Med 3, no. 7 (July 2006): e255. https://doi.org/10.1371/journal.pmed.0030255.Full Text Link to Item
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Mulligan, M. J., N. D. Russell, C. Celum, J. Kahn, E. Noonan, D. C. Montefiori, G. Ferrari, et al. “Excellent safety and tolerability of the human immunodeficiency virus type 1 pGA2/JS2 plasmid DNA priming vector vaccine in HIV type 1 uninfected adults.” Aids Res Hum Retroviruses 22, no. 7 (July 2006): 678–83. https://doi.org/10.1089/aid.2006.22.678.Full Text Link to Item
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Van Rompay, Koen K. A., Raman P. Singh, Walid Heneine, Jeffrey A. Johnson, David C. Montefiori, Norbert Bischofberger, and Marta L. Marthas. “Structured treatment interruptions with tenofovir monotherapy for simian immunodeficiency virus-infected newborn macaques.” J Virol 80, no. 13 (July 2006): 6399–6410. https://doi.org/10.1128/JVI.02308-05.Full Text Link to Item
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Mattapallil, Joseph J., Daniel C. Douek, Alicia Buckler-White, David Montefiori, Norman L. Letvin, Gary J. Nabel, and Mario Roederer. “Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge.” J Exp Med 203, no. 6 (June 12, 2006): 1533–41. https://doi.org/10.1084/jem.20060657.Full Text Link to Item
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Letvin, Norman L., John R. Mascola, Yue Sun, Darci A. Gorgone, Adam P. Buzby, Ling Xu, Zhi-Yong Yang, et al. “Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys.” Science 312, no. 5779 (June 9, 2006): 1530–33. https://doi.org/10.1126/science.1124226.Full Text Link to Item
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Batten, C Jane, Robert De Rose, Kim M. Wilson, Michael B. Agy, Socheata Chea, Ivan Stratov, David C. Montefiori, and Stephen J. Kent. “Comparative evaluation of simian, simian-human, and human immunodeficiency virus infections in the pigtail macaque (Macaca nemestrina) model.” Aids Res Hum Retroviruses 22, no. 6 (June 2006): 580–88. https://doi.org/10.1089/aid.2006.22.580.Full Text Link to Item
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Haynes, Barton F., and David C. Montefiori. “Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates.” Expert Rev Vaccines 5, no. 3 (June 2006): 347–63. https://doi.org/10.1586/14760584.5.3.347.Full Text Link to Item
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Pal, Ranajit, V. S. Kalyanaraman, B. C. Nair, Stephen Whitney, Timothy Keen, Lindsey Hocker, Lauren Hudacik, et al. “Immunization of rhesus macaques with a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine elicits protective antibody response against simian human immunodeficiency virus of R5 phenotype.” Virology 348, no. 2 (May 10, 2006): 341–53. https://doi.org/10.1016/j.virol.2005.12.029.Full Text Link to Item
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Pal, Ranajit, David Venzon, Sampa Santra, Vaniambadi S. Kalyanaraman, David C. Montefiori, Lindsey Hocker, Lauren Hudacik, et al. “Systemic immunization with an ALVAC-HIV-1/protein boost vaccine strategy protects rhesus macaques from CD4+ T-cell loss and reduces both systemic and mucosal simian-human immunodeficiency virus SHIVKU2 RNA levels.” J Virol 80, no. 8 (April 2006): 3732–42. https://doi.org/10.1128/JVI.80.8.3732-3742.2006.Full Text Link to Item
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Haynes, Barton F., Benjiang Ma, David C. Montefiori, Terri Wrin, Christos J. Petropoulos, Laura L. Sutherland, Richard M. Scearce, et al. “Analysis of HIV-1 subtype B third variable region peptide motifs for induction of neutralizing antibodies against HIV-1 primary isolates.” Virology 345, no. 1 (February 5, 2006): 44–55. https://doi.org/10.1016/j.virol.2005.08.042.Full Text Link to Item
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Stratov, Ivan, C Jane Dale, Socheata Chea, David C. Montefiori, Robert De Rose, Jeanette C. Reece, and Stephen J. Kent. “Short communication: characteristics of effective immune control of simian/human immunodeficiency virus in pigtail macaques.” Aids Res Hum Retroviruses 22, no. 1 (January 2006): 27–32. https://doi.org/10.1089/aid.2006.22.27.Full Text Link to Item
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Amara, Rama Rao, Chris Ibegbu, Francois Villinger, David C. Montefiori, Sunita Sharma, Pragati Nigam, Yongxian Xu, Harold M. McClure, and Harriet L. Robinson. “Studies using a viral challenge and CD8 T cell depletions on the roles of cellular and humoral immunity in the control of an SHIV-89.6P challenge in DNA/MVA-vaccinated macaques.” Virology 343, no. 2 (December 20, 2005): 246–55. https://doi.org/10.1016/j.virol.2005.08.027.Full Text Link to Item
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Amara, Rama Rao, Kalpana Patel, Genevieve Niedziela, Pragati Nigam, Sunita Sharma, Silvija I. Staprans, David C. Montefiori, et al. “A combination DNA and attenuated simian immunodeficiency virus vaccine strategy provides enhanced protection from simian/human immunodeficiency virus-induced disease.” J Virol 79, no. 24 (December 2005): 15356–67. https://doi.org/10.1128/JVI.79.24.15356-15367.2005.Full Text Link to Item
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Hammonds, Jason, Xuemin Chen, Timothy Fouts, Anthony DeVico, David Montefiori, and Paul Spearman. “Induction of neutralizing antibodies against human immunodeficiency virus type 1 primary isolates by Gag-Env pseudovirion immunization.” J Virol 79, no. 23 (December 2005): 14804–14. https://doi.org/10.1128/JVI.79.23.14804-14814.2005.Full Text Link to Item
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Metzner, Karin J., Walter J. Moretto, Sean M. Donahoe, Xia Jin, Agegnehu Gettie, David C. Montefiori, Preston A. Marx, James M. Binley, Douglas F. Nixon, and Ruth I. Connor. “Evaluation of CD8+ T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live, attenuated simian immunodeficiency virus.” J Gen Virol 86, no. Pt 12 (December 2005): 3375–84. https://doi.org/10.1099/vir.0.81206-0.Full Text Link to Item
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Lian, Ying, Indresh Srivastava, V Rául Gómez-Román, Jan Zur Megede, Yide Sun, Elaine Kan, Susan Hilt, et al. “Evaluation of envelope vaccines derived from the South African subtype C human immunodeficiency virus type 1 TV1 strain.” J Virol 79, no. 21 (November 2005): 13338–49. https://doi.org/10.1128/JVI.79.21.13338-13349.2005.Full Text Link to Item
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Johnston, Robert E., Philip R. Johnson, Mary J. Connell, David C. Montefiori, Ande West, Martha L. Collier, Chad Cecil, Ronald Swanstrom, Jeffrey A. Frelinger, and Nancy L. Davis. “Vaccination of macaques with SIV immunogens delivered by Venezuelan equine encephalitis virus replicon particle vectors followed by a mucosal challenge with SIVsmE660.” Vaccine 23, no. 42 (October 10, 2005): 4969–79. https://doi.org/10.1016/j.vaccine.2005.05.034.Full Text Link to Item
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Kent, Stephen J., C Jane Dale, Charani Ranasinghe, Ivan Stratov, Robert De Rose, Socheata Chea, David C. Montefiori, et al. “Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3.” Vaccine 23, no. 42 (October 10, 2005): 5009–21. https://doi.org/10.1016/j.vaccine.2005.05.032.Full Text Link to Item
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Goepfert, Paul A., Helen Horton, M Juliana McElrath, Sanjay Gurunathan, Guido Ferrari, Georgia D. Tomaras, David C. Montefiori, et al. “High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects.” J Infect Dis 192, no. 7 (October 1, 2005): 1249–59. https://doi.org/10.1086/432915.Full Text Link to Item
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Pal, Ranajit, Shixia Wang, V. S. Kalyanaraman, B. C. Nair, Stephen Whitney, Timothy Keen, Lindsey Hocker, et al. “Polyvalent DNA prime and envelope protein boost HIV-1 vaccine elicits humoral and cellular responses and controls plasma viremia in rhesus macaques following rectal challenge with an R5 SHIV isolate.” J Med Primatol 34, no. 5–6 (October 2005): 226–36. https://doi.org/10.1111/j.1600-0684.2005.00120.x.Full Text Link to Item
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Ellenberger, Dennis, Linda Wyatt, Bin Li, Suzan Buge, Nattawan Lanier, I Vanesssa Rodriguez, Carlos A. Sariol, et al. “Comparative immunogenicity in rhesus monkeys of multi-protein HIV-1 (CRF02_AG) DNA/MVA vaccines expressing mature and immature VLPs.” Virology 340, no. 1 (September 15, 2005): 21–32. https://doi.org/10.1016/j.virol.2005.06.014.Full Text Link to Item
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Doria-Rose, N. A., G. H. Learn, A. G. Rodrigo, D. C. Nickle, F. Li, M. Mahalanabis, M. T. Hensel, et al. “Human immunodeficiency virus type 1 subtype B ancestral envelope protein is functional and elicits neutralizing antibodies in rabbits similar to those elicited by a circulating subtype B envelope.” J Virol 79, no. 17 (September 2005): 11214–24. https://doi.org/10.1128/JVI.79.17.11214-11224.2005.Full Text Link to Item
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Li, Ming, Feng Gao, John R. Mascola, Leonidas Stamatatos, Victoria R. Polonis, Marguerite Koutsoukos, Gerald Voss, et al. “Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies.” J Virol 79, no. 16 (August 2005): 10108–25. https://doi.org/10.1128/JVI.79.16.10108-10125.2005.Full Text Link to Item
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Peng, Bo, Liqun Rejean Wang, Victor Raúl Gómez-Román, Alberta Davis-Warren, David C. Montefiori, V. S. Kalyanaraman, David Venzon, et al. “Replicating rather than nonreplicating adenovirus-human immunodeficiency virus recombinant vaccines are better at eliciting potent cellular immunity and priming high-titer antibodies.” J Virol 79, no. 16 (August 2005): 10200–209. https://doi.org/10.1128/JVI.79.16.10200-10209.2005.Full Text Link to Item
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Egan, Michael A., Siew Yen Chong, Shakuntala Megati, David C. Montefiori, Nina F. Rose, Jean D. Boyer, Maninder K. Sidhu, et al. “Priming with plasmid DNAs expressing interleukin-12 and simian immunodeficiency virus gag enhances the immunogenicity and efficacy of an experimental AIDS vaccine based on recombinant vesicular stomatitis virus.” Aids Res Hum Retroviruses 21, no. 7 (July 2005): 629–43. https://doi.org/10.1089/aid.2005.21.629.Full Text Link to Item
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Otten, Gillis R., Mary Schaefer, Barbara Doe, Hong Liu, Indresh Srivastava, Jan zur Megede, Jina Kazzaz, et al. “Enhanced potency of plasmid DNA microparticle human immunodeficiency virus vaccines in rhesus macaques by using a priming-boosting regimen with recombinant proteins.” J Virol 79, no. 13 (July 2005): 8189–8200. https://doi.org/10.1128/JVI.79.13.8189-8200.2005.Full Text Link to Item
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Reimann, Keith A., Robert A. Parker, Michael S. Seaman, Kristin Beaudry, Margaret Beddall, Lauren Peterson, Kenneth C. Williams, et al. “Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses.” J Virol 79, no. 14 (July 2005): 8878–85. https://doi.org/10.1128/JVI.79.14.8878-8885.2005.Full Text Link to Item
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Rosati, Margherita, Agneta von Gegerfelt, Patricia Roth, Candido Alicea, Antonio Valentin, Marjorie Robert-Guroff, David Venzon, et al. “DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge.” J Virol 79, no. 13 (July 2005): 8480–92. https://doi.org/10.1128/JVI.79.13.8480-8492.2005.Full Text Link to Item
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Schmitz, Jörn E., R Paul Johnson, Harold M. McClure, Kelledy H. Manson, Michael S. Wyand, Marcelo J. Kuroda, Michelle A. Lifton, et al. “Effect of CD8+ lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239delta3-vaccinated rhesus macaques.” J Virol 79, no. 13 (July 2005): 8131–41. https://doi.org/10.1128/JVI.79.13.8131-8141.2005.Full Text Link to Item
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Qiao, Zhi-Song, Mikyung Kim, Bruce Reinhold, David Montefiori, Jia-huai Wang, and Ellis L. Reinherz. “Design, expression, and immunogenicity of a soluble HIV trimeric envelope fragment adopting a prefusion gp41 configuration.” J Biol Chem 280, no. 24 (June 17, 2005): 23138–46. https://doi.org/10.1074/jbc.M414515200.Full Text Link to Item
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Wang, Shixia, James Arthos, John M. Lawrence, Donald Van Ryk, Innocent Mboudjeka, Siyuan Shen, Te-Hui W. Chou, David C. Montefiori, and Shan Lu. “Enhanced immunogenicity of gp120 protein when combined with recombinant DNA priming to generate antibodies that neutralize the JR-FL primary isolate of human immunodeficiency virus type 1.” J Virol 79, no. 12 (June 2005): 7933–37. https://doi.org/10.1128/JVI.79.12.7933-7937.2005.Full Text Link to Item
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Meyuhas, Ronit, Hava Noy, David C. Montefiori, Galina Denisova, Jonathan M. Gershoni, and Gideon Gross. “HIV-1 neutralization by chimeric CD4-CG10 polypeptides fused to human IgG1.” Mol Immunol 42, no. 9 (May 2005): 1099–1109. https://doi.org/10.1016/j.molimm.2004.11.002.Full Text Link to Item
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Chakrabarti, Bimal K., Xu Ling, Zhi-Yong Yang, David C. Montefiori, Amos Panet, Wing-Pui Kong, Brent Welcher, Mark K. Louder, John R. Mascola, and Gary J. Nabel. “Expanded breadth of virus neutralization after immunization with a multiclade envelope HIV vaccine candidate.” Vaccine 23, no. 26 (May 2005): 3434–45. https://doi.org/10.1016/j.vaccine.2005.01.099.Full Text
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Abdel-Motal, Ussama M., Jacqueline Gillis, Kelledy Manson, Michael Wyand, David Montefiori, Kelly Stefano-Cole, Ronald C. Montelaro, John D. Altman, and R Paul Johnson. “Kinetics of expansion of SIV Gag-specific CD8+ T lymphocytes following challenge of vaccinated macaques.” Virology 333, no. 2 (March 15, 2005): 226–38. https://doi.org/10.1016/j.virol.2004.12.030.Full Text Link to Item
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Barouch, Dan H., Jennifer Powers, Diana M. Truitt, Michael G. Kishko, Janelle C. Arthur, Fred W. Peyerl, Marcelo J. Kuroda, et al. “Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants.” Nat Immunol 6, no. 3 (March 2005): 247–52. https://doi.org/10.1038/ni1167.Full Text Link to Item
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Quinnan, Gerald V., Xiao-Fang Yu, Mark G. Lewis, Peng Fei Zhang, Gerd Sutter, Peter Silvera, Ming Dong, et al. “Protection of rhesus monkeys against infection with minimally pathogenic simian-human immunodeficiency virus: correlations with neutralizing antibodies and cytotoxic T cells.” J Virol 79, no. 6 (March 2005): 3358–69. https://doi.org/10.1128/JVI.79.6.3358-3369.2005.Full Text Link to Item
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Sadagopal, Shanmugalakshmi, Rama Rao Amara, David C. Montefiori, Linda S. Wyatt, Silvija I. Staprans, Natalia L. Kozyr, Harold M. McClure, Bernard Moss, and Harriet L. Robinson. “Signature for long-term vaccine-mediated control of a Simian and human immunodeficiency virus 89.6P challenge: stable low-breadth and low-frequency T-cell response capable of coproducing gamma interferon and interleukin-2.” J Virol 79, no. 6 (March 2005): 3243–53. https://doi.org/10.1128/JVI.79.6.3243-3253.2005.Full Text Link to Item
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Greenier, Jennifer L., Koen K. A. Van Rompay, David Montefiori, Patricia Earl, Bernard Moss, and Marta L. Marthas. “Simian immunodeficiency virus (SIV) envelope quasispecies transmission and evolution in infant rhesus macaques after oral challenge with uncloned SIVmac251: increased diversity is associated with neutralizing antibodies and improved survival in previously immunized animals.” Virol J 2 (February 14, 2005): 11. https://doi.org/10.1186/1743-422X-2-11.Full Text Link to Item
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Van Rompay, Koen K. A., Kristina Abel, Jonathan R. Lawson, Raman P. Singh, Kimberli A. Schmidt, Thomas Evans, Patricia Earl, et al. “Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV.” J Acquir Immune Defic Syndr 38, no. 2 (February 1, 2005): 124–34. https://doi.org/10.1097/00126334-200502010-00002.Full Text Link to Item
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Anderson, David E., Anil Singapuri, Kyung Hee Kang, David C. Montefiori, and José V. Torres. “Timing of retroviral infection influences anamnestic immune response in vaccinated primates.” Viral Immunol 18, no. 4 (2005): 689–94. https://doi.org/10.1089/vim.2005.18.689.Full Text Link to Item
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Gao, Feng, Eric A. Weaver, Zhongjing Lu, Yingying Li, Hua-Xin Liao, Benjiang Ma, S Munir Alam, et al. “Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein.” J Virol 79, no. 2 (January 2005): 1154–63. https://doi.org/10.1128/JVI.79.2.1154-1163.2005.Full Text Link to Item
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Johnson, Philip R., Bruce C. Schnepp, Mary J. Connell, Daniela Rohne, Suzanne Robinson, Georgia R. Krivulka, Carol I. Lord, et al. “Novel adeno-associated virus vector vaccine restricts replication of simian immunodeficiency virus in macaques.” J Virol 79, no. 2 (January 2005): 955–65. https://doi.org/10.1128/JVI.79.2.955-965.2005.Full Text Link to Item
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Kim, Mikyung, Zhi-Song Qiao, David C. Montefiori, Barton F. Haynes, Ellis L. Reinherz, and Hua-Xin Liao. “Comparison of HIV Type 1 ADA gp120 monomers versus gp140 trimers as immunogens for the induction of neutralizing antibodies.” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 58–67. https://doi.org/10.1089/aid.2005.21.58.Full Text Link to Item
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Mascola, John R., Anna Sambor, Kristin Beaudry, Sampa Santra, Brent Welcher, Mark K. Louder, Thomas C. Vancott, et al. “Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins.” J Virol 79, no. 2 (January 2005): 771–79. https://doi.org/10.1128/JVI.79.2.771-779.2005.Full Text Link to Item
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Montefiori, David C. “Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays.” Curr Protoc Immunol Chapter 12 (January 2005): 12.11.1-12.11.17. https://doi.org/10.1002/0471142735.im1211s64.Full Text Link to Item
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Dale, C. J., R. De Rose, I. Stratov, S. Chea, D. C. Montefiori, S. Thomson, I. A. Ramshaw, et al. “Efficacy of DNA and fowlpox virus priming/boosting vaccines for simian/human immunodeficiency virus.” J Virol 78, no. 24 (December 2004): 13819–28. https://doi.org/10.1128/JVI.78.24.13819-13828.2004.Full Text Link to Item
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McKenna, Philip M., Pyone Pyone Aye, Bernhard Dietzschold, David C. Montefiori, Louis N. Martin, Preston A. Marx, Roger J. Pomerantz, Andrew Lackner, and Matthias J. Schnell. “Immunogenicity study of glycoprotein-deficient rabies virus expressing simian/human immunodeficiency virus SHIV89.6P envelope in a rhesus macaque.” J Virol 78, no. 24 (December 2004): 13455–59. https://doi.org/10.1128/JVI.78.24.13455-13459.2004.Full Text Link to Item
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Smith, James M., Rama Rao Amara, David Campbell, Yan Xu, Milloni Patel, Sunita Sharma, Salvatore T. Butera, et al. “DNA/MVA vaccine for HIV type 1: effects of codon-optimization and the expression of aggregates or virus-like particles on the immunogenicity of the DNA prime.” Aids Res Hum Retroviruses 20, no. 12 (December 2004): 1335–47. https://doi.org/10.1089/aid.2004.20.1335.Full Text Link to Item
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Montefiori, David C., Barbara Metch, M Juliana McElrath, Steve Self, Kent J. Weinhold, Lawrence Corey, and Lawrence HIV Vaccine Trials Network. “Demographic factors that influence the neutralizing antibody response in recipients of recombinant HIV-1 gp120 vaccines.” J Infect Dis 190, no. 11 (December 1, 2004): 1962–69. https://doi.org/10.1086/425518.Full Text Link to Item
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Vajdy, Michael, Manmohan Singh, Jina Kazzaz, Elawati Soenawan, Mildred Ugozzoli, Fengmin Zhou, Indresh Srivastava, et al. “Mucosal and systemic anti-HIV responses in rhesus macaques following combinations of intranasal and parenteral immunizations.” Aids Res Hum Retroviruses 20, no. 11 (November 2004): 1269–81. https://doi.org/10.1089/aid.2004.20.1269.Full Text Link to Item
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Egan, Michael A., Siew Yen Chong, Michael Hagen, Shakuntala Megati, Eva B. Schadeck, Priscilla Piacente, Ben-Jiang Ma, et al. “A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques.” Vaccine 22, no. 27–28 (September 9, 2004): 3774–88. https://doi.org/10.1016/j.vaccine.2004.03.011.Full Text Link to Item
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Zhang, Mei-Yun, Xiaodong Xiao, Igor A. Sidorov, Vidita Choudhry, Fatim Cham, Peng Fei Zhang, Peter Bouma, et al. “Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody.” J Virol 78, no. 17 (September 2004): 9233–42. https://doi.org/10.1128/JVI.78.17.9233-9242.2004.Full Text Link to Item
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Staprans, Silvija I., Ashley P. Barry, Guido Silvestri, Jeffrey T. Safrit, Natalia Kozyr, Beth Sumpter, Hanh Nguyen, et al. “Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein.” Proc Natl Acad Sci U S A 101, no. 35 (August 31, 2004): 13026–31. https://doi.org/10.1073/pnas.0404739101.Full Text Link to Item
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Santra, Sampa, Dan H. Barouch, Birgit Korioth-Schmitz, Carol I. Lord, Georgia R. Krivulka, Faye Yu, Margaret H. Beddall, et al. “Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses.” Proc Natl Acad Sci U S A 101, no. 30 (July 27, 2004): 11088–93. https://doi.org/10.1073/pnas.0401954101.Full Text Link to Item
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Letvin, Norman L., Yue Huang, Bimal K. Chakrabarti, Ling Xu, Michael S. Seaman, Kristin Beaudry, Birgit Korioth-Schmitz, et al. “Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys.” J Virol 78, no. 14 (July 2004): 7490–97. https://doi.org/10.1128/JVI.78.14.7490-7497.2004.Full Text Link to Item
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Evans, Thomas G., Sharon Frey, Heidi Israel, Joseph Chiu, Raphaelle El-Habib, Peter Gilbert, Alicia Gaitan, David C. Montefiori, and David C. HIV Vaccine Trials Network (HVTN 803). “Long-term memory B-cell responses in recipients of candidate human immunodeficiency virus type 1 vaccines.” Vaccine 22, no. 20 (June 30, 2004): 2626–30. https://doi.org/10.1016/j.vaccine.2003.12.011.Full Text Link to Item
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Ferrantelli, Flavia, Robert A. Rasmussen, Kathleen A. Buckley, Pei-Lin Li, Tao Wang, David C. Montefiori, Hermann Katinger, et al. “Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies.” J Infect Dis 189, no. 12 (June 15, 2004): 2167–73. https://doi.org/10.1086/420833.Full Text Link to Item
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Haigwood, Nancy L., David C. Montefiori, William F. Sutton, Janela McClure, Andrew J. Watson, Gerald Voss, Vanessa M. Hirsch, et al. “Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies.” J Virol 78, no. 11 (June 2004): 5983–95. https://doi.org/10.1128/JVI.78.11.5983-5995.2004.Full Text Link to Item
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Wyatt, Linda S., Patricia L. Earl, Jin Yan Liu, James M. Smith, David C. Montefiori, Harriet L. Robinson, and Bernard Moss. “Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component.” Aids Res Hum Retroviruses 20, no. 6 (June 2004): 645–53. https://doi.org/10.1089/0889222041217428.Full Text Link to Item
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Liao, Hua-Xin, S Munir Alam, John R. Mascola, James Robinson, Benjiang Ma, David C. Montefiori, Maria Rhein, Laura L. Sutherland, Richard Scearce, and Barton F. Haynes. “Immunogenicity of constrained monoclonal antibody A32-human immunodeficiency virus (HIV) Env gp120 complexes compared to that of recombinant HIV type 1 gp120 envelope glycoproteins.” J Virol 78, no. 10 (May 2004): 5270–78. https://doi.org/10.1128/jvi.78.10.5270-5278.2004.Full Text Link to Item
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Leung, Louisa, Indresh K. Srivastava, Elaine Kan, Harold Legg, Yide Sun, Catherine Greer, David C. Montefiori, Jan zur Megede, and Susan W. Barnett. “Immunogenicity of HIV-1 Env and Gag in baboons using a DNA prime/protein boost regimen.” Aids 18, no. 7 (April 30, 2004): 991–1001. https://doi.org/10.1097/00002030-200404300-00006.Full Text Link to Item
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Mossman, Sally P., Christopher C. Pierce, Andrew J. Watson, Michael N. Robertson, David C. Montefiori, Larene Kuller, Barbra A. Richardson, et al. “Protective immunity to SIV challenge elicited by vaccination of macaques with multigenic DNA vaccines producing virus-like particles.” Aids Res Hum Retroviruses 20, no. 4 (April 2004): 425–34. https://doi.org/10.1089/088922204323048177.Full Text Link to Item
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Ramsburg, Elizabeth, Nina F. Rose, Preston A. Marx, Megan Mefford, Douglas F. Nixon, Walter J. Moretto, David Montefiori, Patricia Earl, Bernard Moss, and John K. Rose. “Highly effective control of an AIDS virus challenge in macaques by using vesicular stomatitis virus and modified vaccinia virus Ankara vaccine vectors in a single-boost protocol.” J Virol 78, no. 8 (April 2004): 3930–40. https://doi.org/10.1128/jvi.78.8.3930-3940.2004.Full Text Link to Item
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Rybarczyk, Brian J., David Montefiori, Philip R. Johnson, Ande West, Robert E. Johnston, and Ronald Swanstrom. “Correlation between env V1/V2 region diversification and neutralizing antibodies during primary infection by simian immunodeficiency virus sm in rhesus macaques.” J Virol 78, no. 7 (April 2004): 3561–71. https://doi.org/10.1128/jvi.78.7.3561-3571.2004.Full Text Link to Item
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Bertley, Frederic M. N., Pamela A. Kozlowski, Shainn-Wei Wang, Joseph Chappelle, Jignesh Patel, Oluwakemi Sonuyi, Gail Mazzara, et al. “Control of simian/human immunodeficiency virus viremia and disease progression after IL-2-augmented DNA-modified vaccinia virus Ankara nasal vaccination in nonhuman primates.” J Immunol 172, no. 6 (March 15, 2004): 3745–57. https://doi.org/10.4049/jimmunol.172.6.3745.Full Text Link to Item
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Hirsch, Vanessa M., Sampa Santra, Simoy Goldstein, Ronald Plishka, Alicia Buckler-White, Aruna Seth, Ilnour Ourmanov, et al. “Immune failure in the absence of profound CD4+ T-lymphocyte depletion in simian immunodeficiency virus-infected rapid progressor macaques.” J Virol 78, no. 1 (January 2004): 275–84. https://doi.org/10.1128/jvi.78.1.275-284.2004.Full Text Link to Item
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Vogel, Thorsten U., Matthew R. Reynolds, Deborah H. Fuller, Kathy Vielhuber, Tim Shipley, James T. Fuller, Kevin J. Kunstman, et al. “Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.” J Virol 77, no. 24 (December 2003): 13348–60. https://doi.org/10.1128/jvi.77.24.13348-13360.2003.Full Text Link to Item
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Buge, Suzan L., Hak-Ling Ma, Rama R. Amara, Linda S. Wyatt, Patricia L. Earl, François Villinger, David C. Montefiori, et al. “Gp120-alum boosting of a Gag-Pol-Env DNA/MVA AIDS vaccine: poorer control of a pathogenic viral challenge.” Aids Res Hum Retroviruses 19, no. 10 (October 2003): 891–900. https://doi.org/10.1089/088922203322493067.Full Text Link to Item
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Mascola, John R., Mark G. Lewis, Thomas C. VanCott, Gabriela Stiegler, Hermann Katinger, Michael Seaman, Kristin Beaudry, et al. “Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies.” J Virol 77, no. 19 (October 2003): 10348–56. https://doi.org/10.1128/jvi.77.19.10348-10356.2003.Full Text Link to Item
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O’Neill, Eduardo, Vanda Bostik, David C. Montefiori, Edmundo Kraiselburd, and François Villinger. “IL-12/GM-CSF coadministration in an SIV DNA prime/protein boost protocol enhances Gag-specific T cells but not virus-specific neutralizing antibodies in rhesus macaques.” Aids Res Hum Retroviruses 19, no. 10 (October 2003): 883–90. https://doi.org/10.1089/088922203322493058.Full Text Link to Item
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Srivastava, Indresh K., Leonidas Stamatatos, Elaine Kan, Michael Vajdy, Ying Lian, Susan Hilt, Loic Martin, et al. “Purification, characterization, and immunogenicity of a soluble trimeric envelope protein containing a partial deletion of the V2 loop derived from SF162, an R5-tropic human immunodeficiency virus type 1 isolate.” J Virol 77, no. 20 (October 2003): 11244–59. https://doi.org/10.1128/jvi.77.20.11244-11259.2003.Full Text Link to Item
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O’Connor, David H., Bianca R. Mothe, Jason T. Weinfurter, Sarah Fuenger, William M. Rehrauer, Peicheng Jing, Richard R. Rudersdorf, et al. “Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.” J Virol 77, no. 16 (August 2003): 9029–40. https://doi.org/10.1128/jvi.77.16.9029-9040.2003.Full Text Link to Item
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Zhao, Jun, Joel Pinczewski, Victor R. Gómez-Román, David Venzon, V. S. Kalyanaraman, Phillip D. Markham, Kristine Aldrich, et al. “Improved protection of rhesus macaques against intrarectal simian immunodeficiency virus SIV(mac251) challenge by a replication-competent Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinant priming/gp120 boosting regimen.” J Virol 77, no. 15 (August 2003): 8354–65. https://doi.org/10.1128/jvi.77.15.8354-8365.2003.Full Text Link to Item
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Montefiori, David C., Marcus Altfeld, Paul K. Lee, Miroslawa Bilska, Jintao Zhou, Mary N. Johnston, Feng Gao, Bruce D. Walker, and Eric S. Rosenberg. “Viremia control despite escape from a rapid and potent autologous neutralizing antibody response after therapy cessation in an HIV-1-infected individual.” J Immunol 170, no. 7 (April 1, 2003): 3906–14. https://doi.org/10.4049/jimmunol.170.7.3906.Full Text Link to Item
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Ambrose, Zandrea, Jannelle Thompson, Kay Larsen, Larene Kuller, Dennis L. Panicali, John D. Clements, Michael Agy, David C. Montefiori, Shiu Lok Hu, and Marnix L. Bosch. “Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6).” Virology 308, no. 1 (March 30, 2003): 178–90. https://doi.org/10.1016/s0042-6822(03)00027-8.Full Text Link to Item
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Abel, Kristina, Lara Compton, Tracy Rourke, David Montefiori, Ding Lu, Kristina Rothaeusler, Linda Fritts, Kristen Bost, and Christopher J. Miller. “Simian-human immunodeficiency virus SHIV89.6-induced protection against intravaginal challenge with pathogenic SIVmac239 is independent of the route of immunization and is associated with a combination of cytotoxic T-lymphocyte and alpha interferon responses.” J Virol 77, no. 5 (March 2003): 3099–3118. https://doi.org/10.1128/jvi.77.5.3099-3118.2003.Full Text Link to Item
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Green, Thomas D., David C. Montefiori, and Ted M. Ross. “Enhancement of antibodies to the human immunodeficiency virus type 1 envelope by using the molecular adjuvant C3d.” J Virol 77, no. 3 (February 2003): 2046–55. https://doi.org/10.1128/jvi.77.3.2046-2055.2003.Full Text Link to Item
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Schmitz, Jörn E., Marcelo J. Kuroda, Sampa Santra, Meredith A. Simon, Michelle A. Lifton, Wenyu Lin, Rajinder Khunkhun, et al. “Effect of humoral immune responses on controlling viremia during primary infection of rhesus monkeys with simian immunodeficiency virus.” J Virol 77, no. 3 (February 2003): 2165–73. https://doi.org/10.1128/jvi.77.3.2165-2173.2003.Full Text Link to Item
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Muthumani, Karuppiah, Mark Bagarazzi, Dan Conway, Daniel S. Hwang, Kelledy Manson, Richard Ciccarelli, Zimmra Israel, et al. “A Gag-Pol/Env-Rev SIV239 DNA vaccine improves CD4 counts, and reduce viral loads after pathogenic intrarectal SIV(mac)251 challenge in rhesus Macaques.” Vaccine 21, no. 7–8 (January 30, 2003): 629–37. https://doi.org/10.1016/s0264-410x(02)00571-6.Full Text Link to Item
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Voss, Gerald, Kelledy Manson, David Montefiori, David I. Watkins, Jonathan Heeney, Michael Wyand, Joe Cohen, and Claudine Bruck. “Prevention of disease induced by a partially heterologous AIDS virus in rhesus monkeys by using an adjuvanted multicomponent protein vaccine.” J Virol 77, no. 2 (January 2003): 1049–58. https://doi.org/10.1128/jvi.77.2.1049-1058.2003.Full Text Link to Item
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Altfeld, Marcus, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, et al. “HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus.” Nature 420, no. 6914 (November 28, 2002): 434–39. https://doi.org/10.1038/nature01200.Full Text Link to Item
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Hel, Zdenek, Janos Nacsa, Elzbieta Tryniszewska, Wen-Po Tsai, Robyn Washington Parks, David C. Montefiori, Barbara K. Felber, James Tartaglia, George N. Pavlakis, and Genoveffa Franchini. “Containment of simian immunodeficiency virus infection in vaccinated macaques: correlation with the magnitude of virus-specific pre- and postchallenge CD4+ and CD8+ T cell responses.” J Immunol 169, no. 9 (November 1, 2002): 4778–87. https://doi.org/10.4049/jimmunol.169.9.4778.Full Text Link to Item
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Shacklett, Barbara L., Karen E. S. Shaw, Lou A. Adamson, David T. Wilkens, Catherine A. Cox, David C. Montefiori, Murray B. Gardner, Pierre Sonigo, and Paul A. Luciw. “Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251.” J Virol 76, no. 22 (November 2002): 11365–78. https://doi.org/10.1128/jvi.76.22.11365-11378.2002.Full Text Link to Item
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Tryniszewska, Elzbieta, Janos Nacsa, Mark G. Lewis, Peter Silvera, David Montefiori, David Venzon, Zdenek Hel, et al. “Vaccination of macaques with long-standing SIVmac251 infection lowers the viral set point after cessation of antiretroviral therapy.” J Immunol 169, no. 9 (November 1, 2002): 5347–57. https://doi.org/10.4049/jimmunol.169.9.5347.Full Text Link to Item
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Allen, Todd M., Peicheng Jing, Briana Calore, Helen Horton, David H. O’Connor, Tomas Hanke, Marian Piekarczyk, et al. “Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.” J Virol 76, no. 20 (October 2002): 10507–11. https://doi.org/10.1128/jvi.76.20.10507-10511.2002.Full Text Link to Item
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Fouts, Timothy, Karla Godfrey, Kathryn Bobb, David Montefiori, Carl V. Hanson, V. S. Kalyanaraman, Anthony DeVico, and Ranajit Pal. “Crosslinked HIV-1 envelope-CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques.” Proc Natl Acad Sci U S A 99, no. 18 (September 3, 2002): 11842–47. https://doi.org/10.1073/pnas.182412199.Full Text Link to Item
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Lewis, Anne D., Ruju Chen, David C. Montefiori, Philip R. Johnson, and K Reed Clark. “Generation of neutralizing activity against human immunodeficiency virus type 1 in serum by antibody gene transfer.” J Virol 76, no. 17 (September 2002): 8769–75. https://doi.org/10.1128/jvi.76.17.8769-8775.2002.Full Text Link to Item
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Amara, Rama Rao, Francois Villinger, Silvija I. Staprans, John D. Altman, David C. Montefiori, Natalia L. Kozyr, Yan Xu, et al. “Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6P mucosal challenge by modified vaccinia virus Ankara (MVA) and DNA/MVA vaccines.” J Virol 76, no. 15 (August 2002): 7625–31. https://doi.org/10.1128/jvi.76.15.7625-7631.2002.Full Text Link to Item
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O’Neill, E., I. Martinez, F. Villinger, M. Rivera, S. Gascot, C. Colon, T. Arana, et al. “Protection by SIV VLP DNA prime/protein boost following mucosal SIV challenge is markedly enhanced by IL-12/GM-CSF co-administration.” J Med Primatol 31, no. 4–5 (August 2002): 217–27. https://doi.org/10.1034/j.1600-0684.2002.02008.x.Full Text Link to Item
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Horton, Helen, Thorsten U. Vogel, Donald K. Carter, Kathy Vielhuber, Deborah H. Fuller, Tim Shipley, James T. Fuller, et al. “Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239.” J Virol 76, no. 14 (July 2002): 7187–7202. https://doi.org/10.1128/jvi.76.14.7187-7202.2002.Full Text Link to Item
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Amara, Rama Rao, James M. Smith, Silvija I. Staprans, David C. Montefiori, Francois Villinger, John D. Altman, Shawn P. O’Neil, et al. “Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime/recombinant modified vaccinia virus Ankara vaccine.” J Virol 76, no. 12 (June 2002): 6138–46. https://doi.org/10.1128/jvi.76.12.6138-6146.2002.Full Text Link to Item
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Chakrabarti, Bimal K., Wing-pui Kong, Bei-yue Wu, Zhi-Yong Yang, Jacques Friborg, Xu Ling, Steven R. King, David C. Montefiori, and Gary J. Nabel. “Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization.” J Virol 76, no. 11 (June 2002): 5357–68. https://doi.org/10.1128/jvi.76.11.5357-5368.2002.Full Text Link to Item
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Hofmann-Lehmann, R., J. Vlasak, R. A. Rasmussen, S. Jiang, P. L. Li, T. W. Baba, D. C. Montefiori, et al. “Postnatal pre- and postexposure passive immunization strategies: protection of neonatal macaques against oral simian-human immunodeficiency virus challenge.” J Med Primatol 31, no. 3 (June 2002): 109–19. https://doi.org/10.1034/j.1600-0684.2002.01014.x.Full Text Link to Item
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Liao, Hua Xin, George J. Cianciolo, Herman F. Staats, Richard M. Scearce, Dana M. Lapple, Stephen H. Stauffer, James R. Thomasch, et al. “Increased immunogenicity of HIV envelope subunit complexed with alpha2-macroglobulin when combined with monophosphoryl lipid A and GM-CSF.” Vaccine 20, no. 17–18 (May 22, 2002): 2396–2403. https://doi.org/10.1016/s0264-410x(02)00090-7.Full Text Link to Item
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Amara, Rama Rao, Francois Villinger, John D. Altman, Shari L. Lydy, Shawn P. O’Neil, Silvija I. Staprans, David C. Montefiori, et al. “Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.” Vaccine 20, no. 15 (May 6, 2002): 1949–55. https://doi.org/10.1016/s0264-410x(02)00076-2.Full Text Link to Item
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Hofmann-Lehmann, Regina, Josef Vlasak, Agnès-Laurence Chenine, Pei-Lin Li, Timothy W. Baba, David C. Montefiori, Harold M. McClure, Daniel C. Anderson, and Ruth M. Ruprecht. “Molecular evolution of human immunodeficiency virus env in humans and monkeys: similar patterns occur during natural disease progression or rapid virus passage.” J Virol 76, no. 10 (May 2002): 5278–84. https://doi.org/10.1128/jvi.76.10.5278-5284.2002.Full Text Link to Item
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Rasmussen, Robert A., Regina Hofmann-Lehmann, Pei-Lin Li, Josef Vlasak, Joern E. Schmitz, Keith A. Reimann, Marcelo J. Kuroda, et al. “Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques.” Aids 16, no. 6 (April 12, 2002): 829–38. https://doi.org/10.1097/00002030-200204120-00002.Full Text Link to Item
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Earl, Patricia L., Linda S. Wyatt, David C. Montefiori, Miroslawa Bilska, Ruth Woodward, Phillip D. Markham, James D. Malley, et al. “Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model.” Virology 294, no. 2 (March 15, 2002): 270–81. https://doi.org/10.1006/viro.2001.1345.Full Text Link to Item
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Bures, Renata, Lynn Morris, Carolyn Williamson, Gita Ramjee, Mark Deers, Susan A. Fiscus, Salim Abdool-Karim, and David C. Montefiori. “Regional clustering of shared neutralization determinants on primary isolates of clade C human immunodeficiency virus type 1 from South Africa.” J Virol 76, no. 5 (March 2002): 2233–44. https://doi.org/10.1128/jvi.76.5.2233-2244.2002.Full Text Link to Item
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Gupta, Kalpana, Michael Hudgens, Lawrence Corey, M Juliana McElrath, Kent Weinhold, David C. Montefiori, Geoffrey J. Gorse, et al. “Safety and immunogenicity of a high-titered canarypox vaccine in combination with rgp120 in a diverse population of HIV-1-uninfected adults: AIDS Vaccine Evaluation Group Protocol 022A.” J Acquir Immune Defic Syndr 29, no. 3 (March 1, 2002): 254–61. https://doi.org/10.1097/00126334-200203010-00005.Full Text Link to Item
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Rasmussen, Robert A., R. Hofmann-Lehman, D. C. Montefiori, P. L. Li, V. Liska, J. Vlasak, T. W. Baba, et al. “DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus.” J Med Primatol 31, no. 1 (February 2002): 40–60. https://doi.org/10.1034/j.1600-0684.2002.1o019.x.Full Text Link to Item
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Barouch, Dan H., Jennifer Kunstman, Marcelo J. Kuroda, Jörn E. Schmitz, Sampa Santra, Fred W. Peyerl, Georgia R. Krivulka, et al. “Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes.” Nature 415, no. 6869 (January 17, 2002): 335–39. https://doi.org/10.1038/415335a.Full Text Link to Item
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Shiver, John W., Tong-Ming Fu, Ling Chen, Danilo R. Casimiro, Mary-Ellen Davies, Robert K. Evans, Zhi-Qiang Zhang, et al. “Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity.” Nature 415, no. 6869 (January 17, 2002): 331–35. https://doi.org/10.1038/415331a.Full Text Link to Item
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Gegerfelt, Agneta S. von, Vladimir Liska, Pei-Lin Li, Harold M. McClure, Kyoji Horie, Filomena Nappi, David C. Montefiori, et al. “Rev-independent simian immunodeficiency virus strains are nonpathogenic in neonatal macaques.” J Virol 76, no. 1 (January 2002): 96–104. https://doi.org/10.1128/jvi.76.1.96-104.2002.Full Text Link to Item
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Letvin, Norman L., Dan H. Barouch, and David C. Montefiori. “Prospects for vaccine protection against HIV-1 infection and AIDS.” Annu Rev Immunol 20 (2002): 73–99. https://doi.org/10.1146/annurev.immunol.20.081501.094854.Full Text Link to Item
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Pal, R., D. Venzon, N. L. Letvin, S. Santra, D. C. Montefiori, N. R. Miller, E. Tryniszewska, et al. “ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency.” J Virol 76, no. 1 (January 2002): 292–302. https://doi.org/10.1128/jvi.76.1.292-302.2002.Full Text Link to Item
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Davis, Nancy L., Ande West, Elizabeth Reap, Gene MacDonald, Martha Collier, Sergey Dryga, Maureen Maughan, et al. “Alphavirus replicon particles as candidate HIV vaccines.” Iubmb Life 53, no. 4–5 (2002): 209–11. https://doi.org/10.1080/15216540212657.Full Text Link to Item
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Rasmussen, R. A., D. C. Montefiori, H. L. Robinson, H. M. McClure, and R. M. Ruprecht. “Heterologous neutralizing antibody induction in a simian-human immunodeficiency virus primate model: lack of original antigenic sin.” J Infect Dis 184, no. 12 (December 15, 2001): 1603–7. https://doi.org/10.1086/324582.Full Text Link to Item
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Juompan, L., J. Zhou, D. C. Montefiori, and F. J. Novembre. “Resistance to neutralizing antibody and expanded coreceptor usage are associated with human immunodeficiency virus type 1 isolates derived from chimpanzees with pathogenic infections.” Aids Res Hum Retroviruses 17, no. 18 (December 10, 2001): 1705–14. https://doi.org/10.1089/08892220152741405.Full Text Link to Item
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Kim, M., B. Chen, R. E. Hussey, Y. Chishti, D. Montefiori, J. A. Hoxie, O. Byron, G. Campbell, S. C. Harrison, and E. L. Reinherz. “The stoichiometry of trimeric SIV glycoprotein interaction with CD4 differs from that of anti-envelope antibody Fab fragments.” J Biol Chem 276, no. 46 (November 16, 2001): 42667–76. https://doi.org/10.1074/jbc.M104166200.Full Text Link to Item
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Ortiz, G. M., M. Wellons, J. Brancato, H. T. Vo, R. L. Zinn, D. E. Clarkson, K. Van Loon, et al. “Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects.” Proc Natl Acad Sci U S A 98, no. 23 (November 6, 2001): 13288–93. https://doi.org/10.1073/pnas.221452198.Full Text Link to Item
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Barouch, D. H., T. M. Fu, D. C. Montefiori, M. G. Lewis, J. W. Shiver, and N. L. Letvin. “Vaccine-elicited immune responses prevent clinical AIDS in SHIV(89.6P)-infected rhesus monkeys.” Immunol Lett 79, no. 1–2 (November 1, 2001): 57–61. https://doi.org/10.1016/s0165-2478(01)00266-8.Full Text Link to Item
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Montefiori, D. C., T. S. Hill, H. T. Vo, B. D. Walker, and E. S. Rosenberg. “Neutralizing antibodies associated with viremia control in a subset of individuals after treatment of acute human immunodeficiency virus type 1 infection.” J Virol 75, no. 21 (November 2001): 10200–207. https://doi.org/10.1128/JVI.75.21.10200-10207.2001.Full Text Link to Item
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Rose, N. F., P. A. Marx, A. Luckay, D. F. Nixon, W. J. Moretto, S. M. Donahoe, D. Montefiori, A. Roberts, L. Buonocore, and J. K. Rose. “An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants.” Cell 106, no. 5 (September 7, 2001): 539–49. https://doi.org/10.1016/s0092-8674(01)00482-2.Full Text Link to Item
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Hofmann-Lehmann, R., J. Vlasak, R. A. Rasmussen, B. A. Smith, T. W. Baba, V. Liska, F. Ferrantelli, et al. “Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge.” J Virol 75, no. 16 (August 2001): 7470–80. https://doi.org/10.1128/JVI.75.16.7470-7480.2001.Full Text Link to Item
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Hofmann-Lehmann, R., R. A. Rasmussen, J. Vlasak, B. A. Smith, T. W. Baba, V. Liska, D. C. Montefiori, et al. “Passive immunization against oral AIDS virus transmission: an approach to prevent mother-to-infant HIV-1 transmission?” J Med Primatol 30, no. 4 (August 2001): 190–96. https://doi.org/10.1034/j.1600-0684.2001.d01-52.x.Full Text Link to Item
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Ruprecht, R. M., R. Hofmann-Lehmann, B. A. Smith-Franklin, R. A. Rasmussen, V. Liska, J. Vlasak, W. Xu, et al. “Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies.” Transfus Clin Biol 8, no. 4 (August 2001): 350–58. https://doi.org/10.1016/s1246-7820(01)00187-2.Full Text Link to Item
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Montefiori, D. C., J. T. Safrit, S. L. Lydy, A. P. Barry, M. Bilska, H. T. Vo, M. Klein, J. Tartaglia, H. L. Robinson, and B. Rovinski. “Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques.” J Virol 75, no. 13 (July 2001): 5879–90. https://doi.org/10.1128/JVI.75.13.5879-5890.2001.Full Text Link to Item
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Ross, T. M., Y. Xu, T. D. Green, D. C. Montefiori, and H. L. Robinson. “Enhanced avidity maturation of antibody to human immunodeficiency virus envelope: DNA vaccination with gp120-C3d fusion proteins.” Aids Res Hum Retroviruses 17, no. 9 (June 10, 2001): 829–35. https://doi.org/10.1089/088922201750252025.Full Text Link to Item
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Barouch, D. H., S. Santra, M. J. Kuroda, J. E. Schmitz, R. Plishka, A. Buckler-White, A. E. Gaitan, et al. “Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination.” J Virol 75, no. 11 (June 2001): 5151–58. https://doi.org/10.1128/JVI.75.11.5151-5158.2001.Full Text Link to Item
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Letvin, N. L., S. Robinson, D. Rohne, M. K. Axthelm, J. W. Fanton, M. Bilska, T. J. Palker, H. X. Liao, B. F. Haynes, and D. C. Montefiori. “Vaccine-elicited V3 loop-specific antibodies in rhesus monkeys and control of a simian-human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate envelope.” J Virol 75, no. 9 (May 2001): 4165–75. https://doi.org/10.1128/JVI.75.9.4165-4175.2001.Full Text Link to Item
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Amara, R. R., F. Villinger, J. D. Altman, S. L. Lydy, S. P. O’Neil, S. I. Staprans, D. C. Montefiori, et al. “Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.” Science 292, no. 5514 (April 6, 2001): 69–74. https://doi.org/10.1126/science.1058915.Full Text Link to Item
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Cho, M. W., Y. B. Kim, M. K. Lee, K. C. Gupta, W. Ross, R. Plishka, A. Buckler-White, et al. “Polyvalent envelope glycoprotein vaccine elicits a broader neutralizing antibody response but is unable to provide sterilizing protection against heterologous Simian/human immunodeficiency virus infection in pigtailed macaques.” J Virol 75, no. 5 (March 2001): 2224–34. https://doi.org/10.1128/JVI.75.5.2224-2234.2001.Full Text Link to Item
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Evans, T. G., M. J. McElrath, T. Matthews, D. Montefiori, K. Weinhold, M. Wolff, M. C. Keefer, et al. “QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immunization in humans.” Vaccine 19, no. 15–16 (February 28, 2001): 2080–91. https://doi.org/10.1016/s0264-410x(00)00415-1.Full Text Link to Item
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Earl, P. L., W. Sugiura, D. C. Montefiori, C. C. Broder, S. A. Lee, C. Wild, J. Lifson, and B. Moss. “Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140.” J Virol 75, no. 2 (January 2001): 645–53. https://doi.org/10.1128/JVI.75.2.645-653.2001.Full Text Link to Item
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Fultz, P. N., P. J. Vance, M. J. Endres, B. Tao, J. D. Dvorin, I. C. Davis, J. D. Lifson, et al. “In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.” J Virol 75, no. 1 (January 2001): 278–91. https://doi.org/10.1128/JVI.75.1.278-291.2001.Full Text Link to Item
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Bures, R., A. Gaitan, T. Zhu, C. Graziosi, K. M. McGrath, J. Tartaglia, P. Caudrelier, et al. “Immunization with recombinant canarypox vectors expressing membrane-anchored glycoprotein 120 followed by glycoprotein 160 boosting fails to generate antibodies that neutralize R5 primary isolates of human immunodeficiency virus type 1.” Aids Res Hum Retroviruses 16, no. 18 (December 10, 2000): 2019–35. https://doi.org/10.1089/088922200750054756.Full Text Link to Item
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Wang, S. W., P. A. Kozlowski, G. Schmelz, K. Manson, M. S. Wyand, R. Glickman, D. Montefiori, et al. “Effective induction of simian immunodeficiency virus-specific systemic and mucosal immune responses in primates by vaccination with proviral DNA producing intact but noninfectious virions.” J Virol 74, no. 22 (November 2000): 10514–22. https://doi.org/10.1128/jvi.74.22.10514-10522.2000.Full Text Link to Item
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Barouch, D. H., S. Santra, J. E. Schmitz, M. J. Kuroda, T. M. Fu, W. Wagner, M. Bilska, et al. “Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination.” Science 290, no. 5491 (October 20, 2000): 486–92. https://doi.org/10.1126/science.290.5491.486.Full Text Link to Item
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Liao, H. X., D. C. Montefiori, D. D. Patel, D. M. Lee, W. K. Scott, M. Pericak-Vance, and B. F. Haynes. “Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA.” J Immunol 165, no. 1 (July 1, 2000): 148–57. https://doi.org/10.4049/jimmunol.165.1.148.Full Text Link to Item
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McElrath, M. J., L. Corey, D. Montefiori, M. Wolff, D. Schwartz, M. Keefer, R. Belshe, et al. “A phase II study of two HIV type 1 envelope vaccines, comparing their immunogenicity in populations at risk for acquiring HIV type 1 infection. AIDS Vaccine Evaluation Group.” Aids Res Hum Retroviruses 16, no. 9 (June 10, 2000): 907–19. https://doi.org/10.1089/08892220050042846.Full Text Link to Item
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Binley, J. M., B. Clas, A. Gettie, M. Vesanen, D. C. Montefiori, L. Sawyer, J. Booth, et al. “Passive infusion of immune serum into simian immunodeficiency virus-infected rhesus macaques undergoing a rapid disease course has minimal effect on plasma viremia.” Virology 270, no. 1 (April 25, 2000): 237–49. https://doi.org/10.1006/viro.2000.0254.Full Text Link to Item
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Barouch, D. H., A. Craiu, M. J. Kuroda, J. E. Schmitz, X. X. Zheng, S. Santra, J. D. Frost, et al. “Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys.” Proc Natl Acad Sci U S A 97, no. 8 (April 11, 2000): 4192–97. https://doi.org/10.1073/pnas.050417697.Full Text Link to Item
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Ourmanov, I., M. Bilska, V. M. Hirsch, and D. C. Montefiori. “Recombinant modified vaccinia virus ankara expressing the surface gp120 of simian immunodeficiency virus (SIV) primes for a rapid neutralizing antibody response to SIV infection in macaques.” J Virol 74, no. 6 (March 2000): 2960–65. https://doi.org/10.1128/jvi.74.6.2960-2965.2000.Full Text Link to Item
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Davis, N. L., I. J. Caley, K. W. Brown, M. R. Betts, D. M. Irlbeck, K. M. McGrath, M. J. Connell, et al. “Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles.” J Virol 74, no. 1 (January 2000): 371–78. https://doi.org/10.1128/jvi.74.1.371-378.2000.Full Text Link to Item
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Haynes, B. F., H. X. Liao, H. F. Staats, M. S. Alam, K. J. Weinhold, and D. C. Montefiori. “HIV vaccine development at Duke University Medical Center.” Immunol Res 22, no. 2–3 (2000): 263–69. https://doi.org/10.1385/ir:22:2-3:263.Full Text Link to Item
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Liao, H. X., B. Etemad-Moghadam, D. C. Montefiori, Y. Sun, J. Sodroski, R. M. Scearce, R. W. Doms, et al. “Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains.” J Virol 74, no. 1 (January 2000): 254–63. https://doi.org/10.1128/jvi.74.1.254-263.2000.Full Text Link to Item
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Robinson, H. L., D. C. Montefiori, R. P. Johnson, M. L. Kalish, S. L. Lydy, and H. M. McClure. “DNA priming and recombinant pox virus boosters for an AIDS vaccine.” Dev Biol (Basel) 104 (2000): 93–100.Link to Item
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Cavacini, L. A., A. Wisnewski, J. E. Peterson, D. Montefiori, C. Emes, M. Duval, G. Kingsbury, A. Wang, D. Scadden, and M. R. Posner. “A human anti-HIV autoantibody enhances EBV transformation and HIV infection.” Clin Immunol 93, no. 3 (December 1999): 263–73. https://doi.org/10.1006/clim.1999.4790.Full Text Link to Item
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Crawford, J. M., P. L. Earl, B. Moss, K. A. Reimann, M. S. Wyand, K. H. Manson, M. Bilska, et al. “Characterization of primary isolate-like variants of simian-human immunodeficiency virus.” J Virol 73, no. 12 (December 1999): 10199–207. https://doi.org/10.1128/JVI.73.12.10199-10207.1999.Full Text Link to Item
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Dreyer, K., E. G. Kallas, V. Planelles, D. Montefiori, M. P. McDermott, M. S. Hasan, and T. G. Evans. “Primary isolate neutralization by HIV type 1-infected patient sera in the era of highly active antiretroviral therapy.” Aids Res Hum Retroviruses 15, no. 17 (November 20, 1999): 1563–71. https://doi.org/10.1089/088922299309856.Full Text Link to Item
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Polacino, P. S., V. Stallard, J. E. Klaniecki, S. Pennathur, D. C. Montefiori, A. J. Langlois, B. A. Richardson, W. R. Morton, R. E. Benveniste, and S. L. Hu. “Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and uncloned virus challenge in Macaques.” J Virol 73, no. 10 (October 1999): 8201–15. https://doi.org/10.1128/JVI.73.10.8201-8215.1999.Full Text Link to Item
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Wyand, M. S., K. Manson, D. C. Montefiori, J. D. Lifson, R. P. Johnson, and R. C. Desrosiers. “Protection by live, attenuated simian immunodeficiency virus against heterologous challenge.” J Virol 73, no. 10 (October 1999): 8356–63. https://doi.org/10.1128/JVI.73.10.8356-8363.1999.Full Text Link to Item
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Wang, C. Y., L. S. Sawyer, K. K. Murthy, X. Fang, A. M. Walfield, J. Ye, J. J. Wang, et al. “Postexposure immunoprophylaxis of primary isolates by an antibody to HIV receptor complex.” Proc Natl Acad Sci U S A 96, no. 18 (August 31, 1999): 10367–72. https://doi.org/10.1073/pnas.96.18.10367.Full Text Link to Item
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Israel, Z. R., A. Gettie, S. T. Ishizaka, E. M. Mishkin, J. Staas, R. Gilley, D. Montefiori, P. A. Marx, and J. H. Eldridge. “Combined systemic and mucosal immunization with microsphere-encapsulated inactivated simian immunodeficiency virus elicits serum, vaginal, and tracheal antibody responses in female rhesus macaques.” Aids Res Hum Retroviruses 15, no. 12 (August 10, 1999): 1121–36. https://doi.org/10.1089/088922299310412.Full Text Link to Item
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Evans, T. G., M. C. Keefer, K. J. Weinhold, M. Wolff, D. Montefiori, G. J. Gorse, B. S. Graham, et al. “A canarypox vaccine expressing multiple human immunodeficiency virus type 1 genes given alone or with rgp120 elicits broad and durable CD8+ cytotoxic T lymphocyte responses in seronegative volunteers.” J Infect Dis 180, no. 2 (August 1999): 290–98. https://doi.org/10.1086/314895.Full Text Link to Item
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Ishizaka, S. T., Z. R. Israel, A. Gettie, E. M. Mishkin, J. K. Staas, R. M. Gilley, P. J. Dailey, D. C. Montefiori, P. A. Marx, and J. H. Eldridge. “Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodeficiency virus in a male urethral challenge model.” Vaccine 17, no. 22 (July 16, 1999): 2817–25. https://doi.org/10.1016/s0264-410x(99)00093-6.Full Text Link to Item
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Liang, X., S. Munshi, J. Shendure, G. Mark, M. E. Davies, D. C. Freed, D. C. Montefiori, and J. W. Shiver. “Epitope insertion into variable loops of HIV-1 gp120 as a potential means to improve immunogenicity of viral envelope protein.” Vaccine 17, no. 22 (July 16, 1999): 2862–72. https://doi.org/10.1016/s0264-410x(99)00125-5.Full Text Link to Item
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Hay, C. M., D. J. Ruhl, N. O. Basgoz, C. C. Wilson, J. M. Billingsley, M. P. DePasquale, R. T. D’Aquila, et al. “Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection.” J Virol 73, no. 7 (July 1999): 5509–19. https://doi.org/10.1128/JVI.73.7.5509-5519.1999.Full Text Link to Item
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Gicheru, M. M., M. Otsyula, P. Spearman, B. S. Graham, C. J. Miller, H. L. Robinson, N. L. Haigwood, and D. C. Montefiori. “Neutralizing antibody responses in Africa green monkeys naturally infected with simian immunodeficiency virus (SIVagm).” J Med Primatol 28, no. 3 (June 1999): 97–104. https://doi.org/10.1111/j.1600-0684.1999.tb00257.x.Full Text Link to Item
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Johnson, R. P., J. D. Lifson, S. C. Czajak, K. S. Cole, K. H. Manson, R. Glickman, J. Yang, et al. “Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation.” J Virol 73, no. 6 (June 1999): 4952–61. https://doi.org/10.1128/JVI.73.6.4952-4961.1999.Full Text Link to Item
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Bradney, A. P., S. Scheer, J. M. Crawford, S. P. Buchbinder, and D. C. Montefiori. “Neutralization escape in human immunodeficiency virus type 1-infected long-term nonprogressors.” J Infect Dis 179, no. 5 (May 1999): 1264–67. https://doi.org/10.1086/314711.Full Text Link to Item
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Robinson, H. L., D. C. Montefiori, R. P. Johnson, K. H. Manson, M. L. Kalish, J. D. Lifson, T. A. Rizvi, et al. “Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations.” Nat Med 5, no. 5 (May 1999): 526–34. https://doi.org/10.1038/8406.Full Text Link to Item
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Polacino, P., V. Stallard, D. C. Montefiori, C. R. Brown, B. A. Richardson, W. R. Morton, R. E. Benveniste, and S. L. Hu. “Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines.” J Virol 73, no. 4 (April 1999): 3134–46. https://doi.org/10.1128/JVI.73.4.3134-3146.1999.Full Text Link to Item
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Evans, D. T., L. A. Knapp, P. Jing, J. L. Mitchen, M. Dykhuizen, D. C. Montefiori, C. D. Pauza, and D. I. Watkins. “Rapid and slow progressors differ by a single MHC class I haplotype in a family of MHC-defined rhesus macaques infected with SIV.” Immunol Lett 66, no. 1–3 (March 1999): 53–59. https://doi.org/10.1016/s0165-2478(98)00151-5.Full Text Link to Item
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Haigwood, N. L., C. C. Pierce, M. N. Robertson, A. J. Watson, D. C. Montefiori, M. Rabin, J. B. Lynch, et al. “Protection from pathogenic SIV challenge using multigenic DNA vaccines.” Immunol Lett 66, no. 1–3 (March 1999): 183–88. https://doi.org/10.1016/s0165-2478(98)00156-4.Full Text Link to Item
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Schmitz, J. E., M. J. Kuroda, S. Santra, V. G. Sasseville, M. A. Simon, M. A. Lifton, P. Racz, et al. “Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes.” Science 283, no. 5403 (February 5, 1999): 857–60. https://doi.org/10.1126/science.283.5403.857.Full Text Link to Item
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Schmitz, J. E., M. A. Lifton, K. A. Reimann, D. C. Montefiori, L. Shen, P. Racz, K. Tenner-Racz, et al. “Effect of complement consumption by cobra venom factor on the course of primary infection with simian immunodeficiency virus in rhesus monkeys.” Aids Res Hum Retroviruses 15, no. 2 (January 20, 1999): 195–202. https://doi.org/10.1089/088922299311619.Full Text Link to Item
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Polacino, P., V. Stallard, J. E. Klaniecki, D. C. Montefiori, A. J. Langlois, B. A. Richardson, J. Overbaugh, W. R. Morton, R. E. Benveniste, and S. L. Hu. “Limited breadth of the protective immunity elicited by simian immunodeficiency virus SIVmne gp160 vaccines in a combination immunization regimen.” J Virol 73, no. 1 (January 1999): 618–30. https://doi.org/10.1128/JVI.73.1.618-630.1999.Full Text Link to Item
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Mossman, S. P., C. C. Pierce, M. N. Robertson, A. J. Watson, D. C. Montefiori, M. Rabin, L. Kuller, et al. “Immunization against SIVmne in macaques using multigenic DNA vaccines.” J Med Primatol 28, no. 4–5 (1999): 206–13. https://doi.org/10.1111/j.1600-0684.1999.tb00271.x.Full Text Link to Item
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Belshe, R. B., G. J. Gorse, M. J. Mulligan, T. G. Evans, M. C. Keefer, J. L. Excler, A. M. Duliege, et al. “Induction of immune responses to HIV-1 by canarypox virus (ALVAC) HIV-1 and gp120 SF-2 recombinant vaccines in uninfected volunteers. NIAID AIDS Vaccine Evaluation Group.” Aids 12, no. 18 (December 24, 1998): 2407–15. https://doi.org/10.1097/00002030-199818000-00009.Full Text Link to Item
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Richmond, J. F., S. Lu, J. C. Santoro, J. Weng, S. L. Hu, D. C. Montefiori, and H. L. Robinson. “Studies of the neutralizing activity and avidity of anti-human immunodeficiency virus type 1 Env antibody elicited by DNA priming and protein boosting.” J Virol 72, no. 11 (November 1998): 9092–9100. https://doi.org/10.1128/JVI.72.11.9092-9100.1998.Full Text Link to Item
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Dykhuizen, M., J. L. Mitchen, D. C. Montefiori, J. Thomson, L. Acker, H. Lardy, and C. D. Pauza. “Determinants of disease in the simian immunodeficiency virus-infected rhesus macaque: characterizing animals with low antibody responses and rapid progression.” J Gen Virol 79 ( Pt 10) (October 1998): 2461–67. https://doi.org/10.1099/0022-1317-79-10-2461.Full Text Link to Item
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Cavacini, L. A., C. L. Emes, A. V. Wisnewski, J. Power, G. Lewis, D. Montefiori, and M. R. Posner. “Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41.” Aids Res Hum Retroviruses 14, no. 14 (September 20, 1998): 1271–80. https://doi.org/10.1089/aid.1998.14.1271.Full Text Link to Item
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Connor, R. I., D. C. Montefiori, J. M. Binley, J. P. Moore, S. Bonhoeffer, A. Gettie, E. A. Fenamore, et al. “Temporal analyses of virus replication, immune responses, and efficacy in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.” J Virol 72, no. 9 (September 1998): 7501–9. https://doi.org/10.1128/JVI.72.9.7501-7509.1998.Full Text Link to Item
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Lu, Y., C. D. Pauza, X. Lu, D. C. Montefiori, and C. J. Miller. “Rhesus macaques that become systemically infected with pathogenic SHIV 89.6-PD after intravenous, rectal, or vaginal inoculation and fail to make an antiviral antibody response rapidly develop AIDS.” J Acquir Immune Defic Syndr Hum Retrovirol 19, no. 1 (September 1, 1998): 6–18. https://doi.org/10.1097/00042560-199809010-00002.Full Text Link to Item
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Hirsch, V. M., G. Dapolito, A. Hahn, J. Lifson, D. Montefiori, C. R. Brown, and R. Goeken. “Viral genetic evolution in macaques infected with molecularly cloned simian immunodeficiency virus correlates with the extent of persistent viremia.” J Virol 72, no. 8 (August 1998): 6482–89. https://doi.org/10.1128/JVI.72.8.6482-6489.1998.Full Text Link to Item
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Langlois, A. J., R. C. Desrosiers, M. G. Lewis, V. N. KewalRamani, D. R. Littman, J. Y. Zhou, K. Manson, M. S. Wyand, D. P. Bolognesi, and D. C. Montefiori. “Neutralizing antibodies in sera from macaques immunized with attenuated simian immunodeficiency virus.” J Virol 72, no. 8 (August 1998): 6950–55. https://doi.org/10.1128/JVI.72.8.6950-6955.1998.Full Text Link to Item
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Benson, J., C. Chougnet, M. Robert-Guroff, D. Montefiori, P. Markham, G. Shearer, R. C. Gallo, et al. “Recombinant vaccine-induced protection against the highly pathogenic simian immunodeficiency virus SIV(mac251): dependence on route of challenge exposure.” J Virol 72, no. 5 (May 1998): 4170–82. https://doi.org/10.1128/JVI.72.5.4170-4182.1998.Full Text Link to Item
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Van Rompay, K. K., C. J. Berardi, S. Dillard-Telm, R. P. Tarara, D. R. Canfield, C. R. Valverde, D. C. Montefiori, et al. “Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection.” J Infect Dis 177, no. 5 (May 1998): 1247–59. https://doi.org/10.1086/515270.Full Text Link to Item
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Montefiori, D. C., K. A. Reimann, M. S. Wyand, K. Manson, M. G. Lewis, R. G. Collman, J. G. Sodroski, D. P. Bolognesi, and N. L. Letvin. “Neutralizing antibodies in sera from macaques infected with chimeric simian-human immunodeficiency virus containing the envelope glycoproteins of either a laboratory-adapted variant or a primary isolate of human immunodeficiency virus type 1.” J Virol 72, no. 4 (April 1998): 3427–31. https://doi.org/10.1128/JVI.72.4.3427-3431.1998.Full Text Link to Item
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Ruprecht, R. M., T. W. Baba, V. Liska, S. Ayehunie, J. Andersen, D. C. Montefiori, A. Trichel, et al. “Oral SIV, SHIV, and HIV type 1 infection.” Aids Res Hum Retroviruses 14 Suppl 1 (April 1998): S97-103.Link to Item
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Montefiori, D. C., R. G. Collman, T. R. Fouts, J. Y. Zhou, M. Bilska, J. A. Hoxie, J. P. Moore, and D. P. Bolognesi. “Evidence that antibody-mediated neutralization of human immunodeficiency virus type 1 by sera from infected individuals is independent of coreceptor usage.” J Virol 72, no. 3 (March 1998): 1886–93. https://doi.org/10.1128/JVI.72.3.1886-1893.1998.Full Text Link to Item
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Lu, S., R. Wyatt, J. F. Richmond, F. Mustafa, S. Wang, J. Weng, D. C. Montefiori, J. Sodroski, and H. L. Robinson. “Immunogenicity of DNA vaccines expressing human immunodeficiency virus type 1 envelope glycoprotein with and without deletions in the V1/2 and V3 regions.” Aids Res Hum Retroviruses 14, no. 2 (January 20, 1998): 151–55. https://doi.org/10.1089/aid.1998.14.151.Full Text Link to Item
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Glamann, J., D. R. Burton, P. W. Parren, H. J. Ditzel, K. A. Kent, C. Arnold, D. Montefiori, and V. M. Hirsch. “Simian immunodeficiency virus (SIV) envelope-specific Fabs with high-level homologous neutralizing activity: recovery from a long-term-nonprogressor SIV-infected macaque.” J Virol 72, no. 1 (January 1998): 585–92. https://doi.org/10.1128/JVI.72.1.585-592.1998.Full Text Link to Item
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Kraiselburd, E. N., A. Salaman, M. Beltrán, M. Rivera, J. Oliver, M. Kessler, M. Knezevich, et al. “Vaccine evaluation studies of replication-defective SIVsmB7.” Cell Mol Biol (Noisy Le Grand) 43, no. 7 (November 1997): 915–24.Link to Item
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Pilgrim, A. K., G. Pantaleo, O. J. Cohen, L. M. Fink, J. Y. Zhou, J. T. Zhou, D. P. Bolognesi, A. S. Fauci, and D. C. Montefiori. “Neutralizing antibody responses to human immunodeficiency virus type 1 in primary infection and long-term-nonprogressive infection.” J Infect Dis 176, no. 4 (October 1997): 924–32. https://doi.org/10.1086/516508.Full Text Link to Item
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Letvin, N. L., D. C. Montefiori, Y. Yasutomi, H. C. Perry, M. E. Davies, C. Lekutis, M. Alroy, et al. “Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination.” Proc Natl Acad Sci U S A 94, no. 17 (August 19, 1997): 9378–83. https://doi.org/10.1073/pnas.94.17.9378.Full Text Link to Item
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Richmond, J. F., F. Mustafa, S. Lu, J. C. Santoro, J. Weng, M. O’Connell, E. M. Fenyö, J. L. Hurwitz, D. C. Montefiori, and H. L. Robinson. “Screening of HIV-1 Env glycoproteins for the ability to raise neutralizing antibody using DNA immunization and recombinant vaccinia virus boosting.” Virology 230, no. 2 (April 14, 1997): 265–74. https://doi.org/10.1006/viro.1997.8478.Full Text Link to Item
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Zhou, J. Y., and D. C. Montefiori. “Antibody-mediated neutralization of primary isolates of human immunodeficiency virus type 1 in peripheral blood mononuclear cells is not affected by the initial activation state of the cells.” J Virol 71, no. 3 (March 1997): 2512–17. https://doi.org/10.1128/JVI.71.3.2512-2517.1997.Full Text Link to Item
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Hirsch, V., D. Adger-Johnson, B. Campbell, S. Goldstein, C. Brown, W. R. Elkins, and D. C. Montefiori. “A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3.” J Virol 71, no. 2 (February 1997): 1608–20. https://doi.org/10.1128/JVI.71.2.1608-1620.1997.Full Text Link to Item
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Burton, D. R., and D. C. Montefiori. “The antibody response in HIV-1 infection.” Aids 11 Suppl A (1997): S87–98.Link to Item
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Montefiori, D. C. “Role of complement and Fc receptors in the pathogenesis of HIV-1 infection.” Springer Semin Immunopathol 18, no. 3 (1997): 371–90. https://doi.org/10.1007/BF00813504.Full Text Link to Item
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Montefiori, D. C., T. W. Baba, A. Li, M. Bilska, and R. M. Ruprecht. “Neutralizing and infection-enhancing antibody responses do not correlate with the differential pathogenicity of SIVmac239delta3 in adult and infant rhesus monkeys.” J Immunol 157, no. 12 (December 15, 1996): 5528–35.Link to Item
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Zhou, J., and D. C. Montefiori. “Complement-activating antibodies in sera from infected individuals and vaccinated volunteers that target human immunodeficiency virus type 1 to complement receptor type 1 (CR1, CD35).” Virology 226, no. 1 (December 1, 1996): 13–21. https://doi.org/10.1006/viro.1996.0623.Full Text Link to Item
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Palker, T. J., A. J. Muir, D. E. Spragion, H. F. Staats, A. Langlois, and D. C. Montefiori. “The V3 domain of SIVmac251 gp120 contains a linear neutralizing epitope.” Virology 224, no. 2 (October 15, 1996): 415–26. https://doi.org/10.1006/viro.1996.0548.Full Text Link to Item
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Hirsch, V. M., T. R. Fuerst, G. Sutter, M. W. Carroll, L. C. Yang, S. Goldstein, M. Piatak, et al. “Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara.” J Virol 70, no. 6 (June 1996): 3741–52. https://doi.org/10.1128/JVI.70.6.3741-3752.1996.Full Text Link to Item
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Lu, S., J. Arthos, D. C. Montefiori, Y. Yasutomi, K. Manson, F. Mustafa, E. Johnson, et al. “Simian immunodeficiency virus DNA vaccine trial in macaques.” J Virol 70, no. 6 (June 1996): 3978–91. https://doi.org/10.1128/JVI.70.6.3978-3991.1996.Full Text Link to Item
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Wyand, M. S., K. H. Manson, M. Garcia-Moll, D. Montefiori, and R. C. Desrosiers. “Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.” J Virol 70, no. 6 (June 1996): 3724–33. https://doi.org/10.1128/JVI.70.6.3724-3733.1996.Full Text Link to Item
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Reimann, K. A., J. T. Li, G. Voss, C. Lekutis, K. Tenner-Racz, P. Racz, W. Lin, et al. “An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys.” J Virol 70, no. 5 (May 1996): 3198–3206. https://doi.org/10.1128/JVI.70.5.3198-3206.1996.Full Text Link to Item
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McElrath, M. J., L. Corey, P. D. Greenberg, T. J. Matthews, D. C. Montefiori, L. Rowen, L. Hood, and J. I. Mullins. “Human immunodeficiency virus type 1 infection despite prior immunization with a recombinant envelope vaccine regimen.” Proc Natl Acad Sci U S A 93, no. 9 (April 30, 1996): 3972–77. https://doi.org/10.1073/pnas.93.9.3972.Full Text Link to Item
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Robinson, H. L., S. Lu, D. M. Feltquate, C. T. Torres, J. Richmond, C. M. Boyle, M. J. Morin, et al. “DNA vaccines.” Aids Res Hum Retroviruses 12, no. 5 (March 20, 1996): 455–57. https://doi.org/10.1089/aid.1996.12.455.Full Text Link to Item
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Montefiori, D. C., G. Pantaleo, L. M. Fink, J. T. Zhou, J. Y. Zhou, M. Bilska, G. D. Miralles, and A. S. Fauci. “Neutralizing and infection-enhancing antibody responses to human immunodeficiency virus type 1 in long-term nonprogressors.” J Infect Dis 173, no. 1 (January 1996): 60–67. https://doi.org/10.1093/infdis/173.1.60.Full Text Link to Item
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Robinson, H. L., S. Lu, F. Mustafa, E. Johnson, J. C. Santoro, J. Arthos, J. Winsink, J. I. Mullins, D. Montefiori, and Y. Yasutomi. “Simian immunodeficiency virus DNA vaccine trial in macaques.” Ann N Y Acad Sci 772 (November 27, 1995): 209–11. https://doi.org/10.1111/j.1749-6632.1995.tb44746.x.Full Text Link to Item
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Cavacini, L. A., C. L. Emes, J. Power, F. D. Desharnais, M. Duval, D. Montefiori, and M. R. Posner. “Influence of heavy chain constant regions on antigen binding and HIV-1 neutralization by a human monoclonal antibody.” J Immunol 155, no. 7 (October 1, 1995): 3638–44.Link to Item
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Montefiori, D. C., K. A. Reimann, N. L. Letvin, J. Zhou, and S. L. Hu. “Studies of complement-activating antibodies in the SIV/macaque model of acute primary infection and vaccine protection.” Aids Res Hum Retroviruses 11, no. 8 (August 1995): 963–70. https://doi.org/10.1089/aid.1995.11.963.Full Text Link to Item
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Goldstein, S., B. Hague, D. Montefiori, and V. M. Hirsch. “A macaque adherent cell line that expresses human CD4 is susceptible to SIV: utility for assessing neutralizing antibody.” J Virol Methods 53, no. 1 (May 1995): 139–48. https://doi.org/10.1016/0166-0934(95)00010-r.Full Text Link to Item
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Pantaleo, G., S. Menzo, M. Vaccarezza, C. Graziosi, O. J. Cohen, J. F. Demarest, D. Montefiori, J. M. Orenstein, C. Fox, and L. K. Schrager. “Studies in subjects with long-term nonprogressive human immunodeficiency virus infection.” N Engl J Med 332, no. 4 (January 26, 1995): 209–16. https://doi.org/10.1056/NEJM199501263320402.Full Text Link to Item
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Montefiori, D. C., R. J. Cornell, J. Y. Zhou, J. T. Zhou, V. M. Hirsch, and P. R. Johnson. “Complement control proteins, CD46, CD55, and CD59, as common surface constituents of human and simian immunodeficiency viruses and possible targets for vaccine protection.” Virology 205, no. 1 (November 15, 1994): 82–92. https://doi.org/10.1006/viro.1994.1622.Full Text Link to Item
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Schlienger, K., D. C. Montefiori, M. Mancini, Y. Rivière, P. Tiollais, and M. L. Michel. “Vaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge.” J Virol 68, no. 10 (October 1994): 6578–88. https://doi.org/10.1128/JVI.68.10.6578-6588.1994.Full Text Link to Item
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Hirsch, V. M., S. Goldstein, N. A. Hynes, W. R. Elkins, W. T. London, P. M. Zack, D. Montefiori, and P. R. Johnson. “Prolonged clinical latency and survival of macaques given a whole inactivated simian immunodeficiency virus vaccine.” J Infect Dis 170, no. 1 (July 1994): 51–59. https://doi.org/10.1093/infdis/170.1.51.Full Text Link to Item
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Javaherian, K., A. J. Langlois, D. C. Montefiori, K. A. Kent, K. A. Ryan, P. D. Wyman, J. Stott, D. P. Bolognesi, M. Murphey-Corb, and G. J. Larosa. “Studies of the conformation-dependent neutralizing epitopes of simian immunodeficiency virus envelope protein.” J Virol 68, no. 4 (April 1994): 2624–31. https://doi.org/10.1128/JVI.68.4.2624-2631.1994.Full Text Link to Item
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Reimann, K. A., K. Tenner-Racz, P. Racz, D. C. Montefiori, Y. Yasutomi, W. Lin, B. J. Ransil, and N. L. Letvin. “Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques.” J Virol 68, no. 4 (April 1994): 2362–70. https://doi.org/10.1128/JVI.68.4.2362-2370.1994.Full Text Link to Item
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Lewis, M. G., W. R. Elkins, F. E. McCutchan, R. E. Benveniste, C. Y. Lai, D. C. Montefiori, D. S. Burke, G. A. Eddy, and A. Shafferman. “Passively transferred antibodies directed against conserved regions of SIV envelope protect macaques from SIV infection.” Vaccine 11, no. 13 (October 1993): 1347–55. https://doi.org/10.1016/0264-410x(93)90106-8.Full Text Link to Item
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Montefiori, D. C., B. S. Graham, J. Zhou, R. A. Bucco, D. H. Schwartz, L. A. Cavacini, and M. R. Posner. “V3-specific neutralizing antibodies in sera from HIV-1 gp160-immunized volunteers block virus fusion and act synergistically with human monoclonal antibody to the conformation-dependent CD4 binding site of gp120. NIH-NIAID AIDS Vaccine Clinical Trials Network.” J Clin Invest 92, no. 2 (August 1993): 840–47. https://doi.org/10.1172/JCI116658.Full Text Link to Item
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Macon, W. R., S. C. Lo, B. J. Poiesz, D. C. Montefiori, M. S. Dawson, T. E. Mason, P. R. Michael, A. G. Cohen, C. M. Davis, and J. B. Cousar. “Acquired immunodeficiency syndrome-like illness associated with systemic Mycoplasma fermentans infection in a human immunodeficiency virus-negative homosexual man.” Hum Pathol 24, no. 5 (May 1993): 554–58. https://doi.org/10.1016/0046-8177(93)90169-h.Full Text Link to Item
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Montefiori, D. C., K. Stewart, J. M. Ahearn, and J. Zhou. “Complement-mediated binding of naturally glycosylated and glycosylation-modified human immunodeficiency virus type 1 to human CR2 (CD21).” J Virol 67, no. 5 (May 1993): 2699–2706. https://doi.org/10.1128/JVI.67.5.2699-2706.1993.Full Text Link to Item
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Smallheer, J. M., M. J. Otto, C. A. Amaral-Ly, R. A. Earl, M. J. Myers, P. Pennev, D. C. Montefiori, and M. A. Wuonola. “Synthesis and anti-HIV activity of a series of 2-indolinones and related analogues.” Antiviral Chemistry and Chemotherapy 4, no. 1 (January 1, 1993): 27–39. https://doi.org/10.1177/095632029300400104.Full Text
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Montefiori, D. C., J. Zhou, and D. I. Shaff. “CD4-independent binding of HIV-1 to the B lymphocyte receptor CR2 (CD21) in the presence of complement and antibody.” Clin Exp Immunol 90, no. 3 (December 1992): 383–89. https://doi.org/10.1111/j.1365-2249.1992.tb05855.x.Full Text Link to Item
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Johnson, P. R., D. C. Montefiori, S. Goldstein, T. E. Hamm, J. Zhou, S. Kitov, N. L. Haigwood, L. Misher, W. T. London, and J. L. Gerin. “Inactivated whole SIV vaccine in macaques: evaluation of protective efficacy against challenge with cell-free virus or infected cells.” Aids Res Hum Retroviruses 8, no. 8 (August 1992): 1501–5. https://doi.org/10.1089/aid.1992.8.1501.Full Text Link to Item
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Graham, B. S., R. B. Belshe, M. L. Clements, R. Dolin, L. Corey, P. F. Wright, G. J. Gorse, K. Midthun, M. C. Keefer, and N. J. Roberts. “Vaccination of vaccinia-naive adults with human immunodeficiency virus type 1 gp160 recombinant vaccinia virus in a blinded, controlled, randomized clinical trial. The AIDS Vaccine Clinical Trials Network.” J Infect Dis 166, no. 2 (August 1992): 244–52. https://doi.org/10.1093/infdis/166.2.244.Full Text Link to Item
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Johnson, P. R., D. C. Montefiori, S. Goldstein, T. E. Hamm, J. Zhou, S. Kitov, N. L. Haigwood, L. Misher, W. T. London, and J. L. Gerin. “Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge.” Proc Natl Acad Sci U S A 89, no. 6 (March 15, 1992): 2175–79. https://doi.org/10.1073/pnas.89.6.2175.Full Text Link to Item
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Montefiori, D. C., I. Y. Zhou, B. Barnes, D. Lake, E. M. Hersh, Y. Masuho, and L. B. Lefkowitz. “Homotypic antibody responses to fresh clinical isolates of human immunodeficiency virus.” Virology 182, no. 2 (June 1991): 635–43. https://doi.org/10.1016/0042-6822(91)90604-a.Full Text Link to Item
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Dolin, R., B. S. Graham, S. B. Greenberg, C. O. Tacket, R. B. Belshe, K. Midthun, M. L. Clements, G. J. Gorse, B. W. Horgan, and R. L. Atmar. “The safety and immunogenicity of a human immunodeficiency virus type 1 (HIV-1) recombinant gp160 candidate vaccine in humans. NIAID AIDS Vaccine Clinical Trials Network.” Ann Intern Med 114, no. 2 (January 15, 1991): 119–27. https://doi.org/10.7326/0003-4819-114-2-119.Full Text Link to Item
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Montefiori, D. C., and J. Y. Zhou. “Selective antiviral activity of synthetic soluble L-tyrosine and L-dopa melanins against human immunodeficiency virus in vitro.” Antiviral Res 15, no. 1 (January 1991): 11–25. https://doi.org/10.1016/0166-3542(91)90037-r.Full Text Link to Item
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Graham, B. S., J. M. Rowland, A. Modliszewski, and D. C. Montefiori. “Antifusion activity in sera from persons infected with human immunodeficiency virus type 1.” J Clin Microbiol 28, no. 12 (December 1990): 2608–11. https://doi.org/10.1128/jcm.28.12.2608-2611.1990.Full Text Link to Item
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Montefiori, D. C., M. Murphey-Corb, R. C. Desrosiers, and M. D. Daniel. “Complement-mediated, infection-enhancing antibodies in plasma from vaccinated macaques before and after inoculation with live simian immunodeficiency virus.” J Virol 64, no. 10 (October 1990): 5223–25. https://doi.org/10.1128/JVI.64.10.5223-5225.1990.Full Text Link to Item
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Montefiori, D. C., A. Modliszewski, D. I. Shaff, and J. Zhou. “Inhibition of human immunodeficiency virus type 1 replication and cytopathicity by synthetic soluble catecholamine melanins in vitro.” Biochem Biophys Res Commun 168, no. 1 (April 16, 1990): 200–205. https://doi.org/10.1016/0006-291x(90)91694-n.Full Text Link to Item
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Montefiori, D. C., W. E. Robinson, A. Modliszewski, and W. M. Mitchell. “Effective inactivation of human immunodeficiency virus with chlorhexidine antiseptics containing detergents and alcohol.” J Hosp Infect 15, no. 3 (April 1990): 279–82. https://doi.org/10.1016/0195-6701(90)90036-n.Full Text Link to Item
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Robinson, W. E., D. C. Montefiori, and W. M. Mitchell. “Complement-mediated antibody-dependent enhancement of HIV-1 infection requires CD4 and complement receptors.” Virology 175, no. 2 (April 1990): 600–604. https://doi.org/10.1016/0042-6822(90)90449-2.Full Text Link to Item
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Montefiori, D. C., W. E. Robinson, A. Modliszewski, J. M. Rowland, S. S. Schuffman, and W. M. Mitchell. “Differential inhibition of HIV-1 cell binding and HIV-1-induced syncytium formation by low molecular weight sulphated polysaccharides.” J Antimicrob Chemother 25, no. 3 (March 1990): 313–18. https://doi.org/10.1093/jac/25.3.313.Full Text Link to Item
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Montefiori, D. C., W. E. Robinson, V. M. Hirsch, A. Modliszewski, W. M. Mitchell, and P. R. Johnson. “Antibody-dependent enhancement of SIV infection: further characterization and cross reactivity between macaque and sooty mangabey isolates.” J Med Primatol 19, no. 3–4 (1990): 269–78.Link to Item
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Montefiori, D. C., W. E. Robinson, V. M. Hirsch, A. Modliszewski, W. M. Mitchell, and P. R. Johnson. “Antibody-dependent enhancement of simian immunodeficiency virus (SIV) infection in vitro by plasma from SIV-infected rhesus macaques.” J Virol 64, no. 1 (January 1990): 113–19. https://doi.org/10.1128/JVI.64.1.113-119.1990.Full Text Link to Item
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Robinson, W. E., D. C. Montefiori, W. M. Mitchell, A. M. Prince, H. J. Alter, G. R. Dreesman, and J. W. Eichberg. “Antibody-dependent enhancement of human immunodeficiency virus type 1 (HIV-1) infection in vitro by serum from HIV-1-infected and passively immunized chimpanzees.” Proc Natl Acad Sci U S A 86, no. 12 (June 1989): 4710–14. https://doi.org/10.1073/pnas.86.12.4710.Full Text Link to Item
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Montefiori, D. C., W. E. Robinson, and W. M. Mitchell. “Antibody-independent, complement-mediated enhancement of HIV-1 infection by mannosidase I and II inhibitors.” Antiviral Res 11, no. 3 (April 1989): 137–46. https://doi.org/10.1016/0166-3542(89)90025-9.Full Text Link to Item
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Montefiori, D. C., W. E. Robinson, and W. M. Mitchell. “In vitro evaluation of mismatched double-stranded RNA (ampligen) for combination therapy in the treatment of acquired immunodeficiency syndrome.” Aids Res Hum Retroviruses 5, no. 2 (April 1989): 193–203. https://doi.org/10.1089/aid.1989.5.193.Full Text Link to Item
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Montefiori, D. C., M. G. Pellegrino, W. E. Robinson, K. Engle, M. Field, W. M. Mitchell, and D. H. Gillespie. “Inhibition of HIV-1 proviral DNA synthesis and RNA accumulation by mismatched dsRNA.” Biochem Biophys Res Commun 158, no. 3 (February 15, 1989): 943–50. https://doi.org/10.1016/0006-291x(89)92813-1.Full Text Link to Item
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Charubala, R., R. J. Suhadolnik, B. Lebleu, W. Pfleiderer, and D. C. Montefiori. “Phosphorothioate Analogs Of 2-5A: Activation / Inhibition Of Rnase L And Inhibition Of Hiv-1 Reverse Transcriptase.” Nucleosides and Nucleotides 8, no. 5–6 (January 1, 1989): 987–90. https://doi.org/10.1080/07328318908054260.Full Text
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Robinson, W. E., D. C. Montefiori, D. H. Gillespie, and W. M. Mitchell. “Complement-mediated, antibody-dependent enhancement of HIV-1 infection in vitro is characterized by increased protein and RNA syntheses and infectious virus release.” J Acquir Immune Defic Syndr (1988) 2, no. 1 (1989): 33–42.Link to Item
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Montefiori, D. C., W. E. Robinson, and W. M. Mitchell. “Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.” Proc Natl Acad Sci U S A 85, no. 23 (December 1988): 9248–52. https://doi.org/10.1073/pnas.85.23.9248.Full Text Link to Item
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Robinson, W. E., W. M. Mitchell, W. H. Chambers, S. S. Schuffman, D. C. Montefiori, and T. N. Oeltmann. “Natural killer cell infection and inactivation in vitro by the human immunodeficiency virus.” Hum Pathol 19, no. 5 (May 1988): 535–40. https://doi.org/10.1016/s0046-8177(88)80200-4.Full Text Link to Item
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Robinson, W. E., D. C. Montefiori, and W. M. Mitchell. “Antibody-dependent enhancement of human immunodeficiency virus type 1 infection.” Lancet 1, no. 8589 (April 9, 1988): 790–94. https://doi.org/10.1016/s0140-6736(88)91657-1.Full Text Link to Item
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Montefiori, D. C., W. E. Robinson, S. S. Schuffman, and W. M. Mitchell. “Evaluation of antiviral drugs and neutralizing antibodies to human immunodeficiency virus by a rapid and sensitive microtiter infection assay.” J Clin Microbiol 26, no. 2 (February 1988): 231–35. https://doi.org/10.1128/jcm.26.2.231-235.1988.Full Text Link to Item
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Montefiori, D. C., W. E. Robinson, and W. M. Mitchell. “Mismatched dsRNA (ampligen) induces protection against genomic variants of the human immunodeficiency virus type 1 (HIV-1) in a multiplicity of target cells.” Antiviral Res 9, no. 1–2 (1988): 47–55. https://doi.org/10.1016/0166-3542(88)90066-6.Full Text Link to Item
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Robinson, W. E., D. C. Montefiori, and W. M. Mitchell. “A human immunodeficiency virus type 1 (HIV-1) infection-enhancing factor in seropositive sera.” Biochem Biophys Res Commun 149, no. 2 (December 16, 1987): 693–99. https://doi.org/10.1016/0006-291x(87)90423-2.Full Text Link to Item
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Montefiori, D. C., and W. M. Mitchell. “Persistent coinfection of T lymphocytes with HTLV-II and HIV and the role of syncytium formation in HIV-induced cytopathic effect.” Virology 160, no. 2 (October 1987): 372–78. https://doi.org/10.1016/0042-6822(87)90008-0.Full Text Link to Item
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Carter, W. A., D. R. Strayer, I. Brodsky, M. Lewin, M. G. Pellegrino, L. Einck, H. F. Henriques, G. L. Simon, D. M. Parenti, and R. G. Scheib. “Clinical, immunological, and virological effects of ampligen, a mismatched double-stranded RNA, in patients with AIDS or AIDS-related complex.” Lancet 1, no. 8545 (June 6, 1987): 1286–92. https://doi.org/10.1016/s0140-6736(87)90543-5.Full Text Link to Item
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Montefiori, D. C., and W. M. Mitchell. “Antiviral activity of mismatched double-stranded RNA against human immunodeficiency virus in vitro.” Proc Natl Acad Sci U S A 84, no. 9 (May 1987): 2985–89. https://doi.org/10.1073/pnas.84.9.2985.Full Text Link to Item
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Mitchell, W. M., D. C. Montefiori, W. E. Robinson, D. R. Strayer, and W. A. Carter. “Mismatched double-stranded RNA (ampligen) reduces concentration of zidovudine (azidothymidine) required for in-vitro inhibition of human immunodeficiency virus.” Lancet 1, no. 8538 (April 18, 1987): 890–92. https://doi.org/10.1016/s0140-6736(87)92862-5.Full Text Link to Item
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Robinson, W. E., D. C. Montefiori, and W. M. Mitchell. “Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis.” Aids Res Hum Retroviruses 3, no. 3 (1987): 265–82. https://doi.org/10.1089/aid.1987.3.265.Full Text Link to Item
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Montefiori, D. C., and W. M. Mitchell. “Infection of the HTLV-II-bearing T-cell line C3 with HTLV-III/LAV is highly permissive and lytic.” Virology 155, no. 2 (December 1986): 726–31. https://doi.org/10.1016/0042-6822(86)90233-3.Full Text Link to Item
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Brown, T. M., D. R. Johnson, J. A. Durant, D. C. Montefiori, and A. R. Hopkins. “Interactions of Pyrethroid Insecticides and Toxaphene in Cotton.” Journal of Agricultural and Food Chemistry 30, no. 3 (January 1, 1982): 542–45. https://doi.org/10.1021/jf00111a033.Full Text
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Montefiori, D. C., and E. L. Kline. “Regulation of cell division and of tyrosinase in B16 melanoma cells by imidazole: a possible role for the concept of metabolite gene regulation in mammalian cells.” J Cell Physiol 106, no. 2 (February 1981): 283–91. https://doi.org/10.1002/jcp.1041060215.Full Text Link to Item
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Kline, E. L., V. A. Bankaitis, C. S. Brown, and D. C. Montefiori. “Metabolite gene regulation: imidazole and imidazole derivatives which circumvent cyclic adenosine 3',5'-monophosphate in induction of the Escherichia coli L-arabinose operon.” J Bacteriol 141, no. 2 (February 1980): 770–78. https://doi.org/10.1128/jb.141.2.770-778.1980.Full Text Link to Item
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Kline, E. L., V. Bankaitis, C. S. Brown, and D. Montefiori. “Imidazole acetic acid as a substitute for cAMP.” Biochem Biophys Res Commun 87, no. 2 (March 30, 1979): 566–74. https://doi.org/10.1016/0006-291x(79)91832-1.Full Text Link to Item
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Roome, A. P., D. Montefiore, and D. Waller. “Incidence of Herpesvirus hominis antibodies among blood donor populations.” Br J Vener Dis 51, no. 5 (October 1975): 324–28. https://doi.org/10.1136/sti.51.5.324.Full Text Link to Item
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Fouts, T. R., K. Bagley, I. J. Prado, K. L. Bobb, J. A. Schwartz, R. Xu, R. J. Zagursky, et al. “Erratum: Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (E992–E999) DOI: 10.1073/pnas.1423669112).” Proceedings of the National Academy of Sciences of the United States of America, May 5, 2015. https://doi.org/10.1073/pnas.1506010112.Full Text
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Chakrabarti, B. K., Y. Feng, S. K. Sharma, K. McKee, G. B. Karlsson Hedestam, C. C. LaBranche, D. C. Montefiori, J. R. Mascola, and R. T. Wyatt. “Correction for Chakrabarti et al., Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates.” J Virol, January 1, 2015. https://doi.org/10.1128/JVI.02670-14.Full Text Link to Item
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Han, D., H. Habte, Y. Qin, K. Takamoto, C. LaBranche, D. Montefiori, and M. W. Cho. “Retraction: eliciting broadly neutralizing antibodies against HIV-1 that target gp41 MPER.” Retrovirology, February 6, 2014. https://doi.org/10.1186/1742-4690-11-16.Full Text Link to Item
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Khattar, S. K., S. Samal, C. C. Labranche, D. C. Montefiori, P. L. Collins, and S. K. Samal. “Correction: Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector.” Plos One, 2014. https://doi.org/10.1371/annotation/670112f8-b4fd-4622-8a8c-203dc647f807.Full Text Link to Item
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Montefiori, David C. “Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy.” Hum Vaccin Immunother, 2014. https://doi.org/10.4161/hv.28950.Full Text Link to Item
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Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, X. Shen, R. Schutte, Y. Wang, et al. “Erratum to Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies [Journal of Virology, 85, 21, (2011) 11401-11408] DOI: 10.1128/JVI.05312-11.” Journal of Virology, December 1, 2013. https://doi.org/10.1128/JVI.02726-13.Full Text
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Jiang, H., C. G. Hester, L. Liao, D. C. Montefiori, and M. M. Frank. “Erratum to: Mechanisms by which HIV envelope minimizes immunogenicity (Immunologic Research DOI: 10.1007/s12026-010-8178-6).” Immunologic Research, April 1, 2011. https://doi.org/10.1007/s12026-010-8202-x.Full Text
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Montefiori, D., and J. Mascola. “Editorial introductions.” Current Opinion in Hiv and Aids, September 1, 2009. https://doi.org/10.1097/COH.0b013e3283304ea1.Full Text
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Montefiori, David C., and John R. Mascola. “Neutralizing antibodies against HIV-1: can we elicit them with vaccines and how much do we need?” Curr Opin Hiv Aids, September 2009. https://doi.org/10.1097/COH.0b013e32832f4a4d.Full Text Link to Item
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Siddappa, N. B., R. Song, V. G. Kramer, A. L. Chenine, V. Velu, H. Ong, R. A. Rasmussen, et al. “Neutralization-sensitive R5-tropic simian-human immunodeficiency virus SHIV-2873Nip, which carries env isolated from an infant with a recent HIV clade C infection (Journal of Virology (2009) 83, 3, (1422-1432)).” Journal of Virology, August 1, 2009. https://doi.org/10.1128/JVI.01123-09.Full Text
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Yeh, W. W., P. Jaru-ampornpan, D. Nevidomskyte, M. Asmal, S. S. Rao, A. P. Buzby, D. C. Montefiori, B. T. Korber, and N. L. Letvin. “Partial protection of simian immunodeficiency virus (SIV)-infected rhesus monkeys against superinfection with a heterologous SIV isolate (Journal of Virology (2009) 83, 6 (2686-2696)).” Journal of Virology, May 1, 2009. https://doi.org/10.1128/JVI.00496-09.Full Text
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Wang, Shixia, Jeffrey S. Kennedy, Kim West, David C. Montefiori, Scott Coley, John Lawrence, Siyuan Shen, et al. “Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers.” Vaccine, July 23, 2008. https://doi.org/10.1016/j.vaccine.2007.12.060.Full Text Link to Item
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Montefiori, D., Q. Sattentau, J. Flores, J. Esparza, and J. Mascola. “Antibody-based HIV-1 vaccines: Recent developments and future directions: A summary report from a Global HIV Vaccine Enterprise Working Group.” Plos Medicine, December 1, 2007. https://doi.org/10.1371/journal.pmed.0040348.Full Text
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Choudhry, V., M. Y. Zhang, I. A. Sidorov, J. M. Louis, I. Harris, A. S. Dimitrov, P. Bouma, et al. “Corrigendum to "Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies" [Virology 363 (2007) 79-90] (DOI:10.1016/j.virol.2007.01.015).” Virology, November 25, 2007. https://doi.org/10.1016/j.virol.2007.09.004.Full Text
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Ahuja, Sunil K., Fernando Aiuti, Ben Berkhout, Peter Biberfeld, Dennis R. Burton, Vittorio Colizzi, Steven G. Deeks, et al. “A plea for justice for jailed medical workers.” Science, November 10, 2006. https://doi.org/10.1126/science.1136578.Full Text Link to Item
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Mascola, John R., Patricia D’Souza, Peter Gilbert, Beatrice H. Hahn, Nancy L. Haigwood, Lynn Morris, Christos J. Petropoulos, Victoria R. Polonis, Marcella Sarzotti, and David C. Montefiori. “Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines.” J Virol, August 2005. https://doi.org/10.1128/JVI.79.16.10103-10107.2005.Full Text Link to Item
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Montefiori, David C. “Neutralizing antibodies take a swipe at HIV in vivo.” Nat Med, June 2005. https://doi.org/10.1038/nm0605-593.Full Text Link to Item
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Knechtle, S., G. Remuzzi, and R. M. Strieter. “Editorial introductions.” Current Opinion in Organ Transplantation, December 1, 2004.
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Mascola, John R., and David C. Montefiori. “HIV-1: nature's master of disguise.” Nat Med, April 2003. https://doi.org/10.1038/nm0403-393.Full Text Link to Item
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Altfeld, M., T. M. Allen, X. G. Yu, M. N. Johnston, D. Agrawal, B. T. Korber, D. C. Montefiori, et al. “Erratum: HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus (Nature (2002) 420 (434-439)).” Nature, 2003.
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AIDS Vaccine Evaluation Group 022 Protocol Team, J. O. “Cellular and humoral immune responses to a canarypox vaccine containing human immunodeficiency virus type 1 Env, Gag, and Pro in combination with rgp120.” J Infect Dis, February 15, 2001. https://doi.org/10.1086/318523.Full Text Link to Item
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Sabbaj, S., M. J. Mulligan, R. H. Hsieh, R. B. Belshe, and J. R. McGhee. “Cytokine profiles in seronegative volunteers immunized with a recombinant canarypox and gp120 prime-boost HIV-1 vaccine. NIAID AIDS Vaccine Evaluation Group.” Aids, July 7, 2000. https://doi.org/10.1097/00002030-200007070-00009.Full Text Link to Item
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Davis, N. L., I. J. Caley, K. W. Brown, M. R. Betts, D. M. Irlbeck, K. M. McGrath, M. J. Connell, et al. “Erratum: Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles (Journal of Virology (2000) 74:1 (371-378)).” Journal of Virology, January 1, 2000. https://doi.org/10.1128/JVI.74.7.3430-3430.2000.Full Text
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Montefiori, D., and J. P. Moore. “HIV vaccines. Magic of the occult?” Science, January 15, 1999. https://doi.org/10.1126/science.283.5400.336.Full Text Link to Item
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Montefiori, D. C. “New insights into the role of host cell proteins in antiviral vaccine protection.” Aids Res Hum Retroviruses, December 1995. https://doi.org/10.1089/aid.1995.11.1429.Full Text Link to Item
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Henry, N. W., and D. C. Montefiori. “Resistance of clothing materials to biological liquids.” Astm Special Technical Publication, December 1, 1992.
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“AIDS response.” Nature, December 12, 1991. https://doi.org/10.1038/354439c0.Full Text Link to Item
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Montefiori, D. C. “Progress in AIDS vaccine development.” Infectious Diseases Newsletter, January 1, 1990. https://doi.org/10.1016/0278-2316(90)90044-G.Full Text
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Robinson, W. E., D. C. Montefiori, and W. M. Mitchell. “Will antibody-dependent enhancement of HIV-1 infection be a problem with AIDS vaccines?” Lancet, April 9, 1988. https://doi.org/10.1016/s0140-6736(88)91695-9.Full Text Link to Item
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Montefiori, D. C., W. Edward Robinson, and W. M. Mitchell. “Antibody-dependent enhancement of viral infectivity: III. Relation to the development of a vaccine against human immunodeficiency virus.” Infectious Diseases Newsletter, January 1, 1988. https://doi.org/10.1016/0278-2316(88)90018-7.Full Text
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Robinson, W. E., D. C. Montefiori, and W. M. Mitchell. “Antibody-dependent enhancement of viral infectivity: II. Potential significance in aids.” Infectious Diseases Newsletter, January 1, 1988. https://doi.org/10.1016/0278-2316(88)90034-5.Full Text
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Conference Papers
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Eslamizar, L., C. Petrovas, D. J. Leggat, K. Furr, M. L. Lifton, G. Levine, S. Ma, et al. “Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center.” In Npj Vaccines, Vol. 6, 2021. https://doi.org/10.1038/s41541-020-00277-1.Full Text
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Sliepen, K., B. W. Han, I. Bontjer, P. Mooij, F. Garces, A. J. Behrens, K. Rantalainen, et al. “Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.” In Nature Communications, Vol. 10, 2019. https://doi.org/10.1038/s41467-019-10262-5.Full Text
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Asbach, Benedikt, Karen V. Kibler, Josef Köstler, Beatriz Perdiguero, Nicole L. Yates, Sherry Stanfield-Oakley, Georgia D. Tomaras, et al. “Priming with a Potent HIV-1 DNA Vaccine Frames the Quality of Immune Responses prior to a Poxvirus and Protein Boost.” In J Virol, Vol. 93, 2019. https://doi.org/10.1128/JVI.01529-18.Full Text Link to Item
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Behrens, Shay, Celia C. LaBranche, Tongqing Zhou, Kevin Wiehe, Mattia Bonsignori, Quentin J. Sattentau, Amanda Eaton, et al. “Germline-targeting and Reverse Engineering to Elicit CH235.12 Lineage bNAbs.” In Aids Research and Human Retroviruses, 34:116–116. MARY ANN LIEBERT, INC, 2018.Link to Item
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Bonsignori, Mattia, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam, Kwan-Ki Hwang, David C. Montefiori, et al. “Dual Maturation Pathways from the Unmutated Common Ancestor of HIV-1 Envelope Broadly Neutralizing Antibodies Overcome Glycan Barriers.” In Aids Research and Human Retroviruses, 34:111–111. MARY ANN LIEBERT, INC, 2018.Link to Item
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Kimpel, Janine, C Anika Bresk, Tamara Hofer, Sarah Wilmschen, Marina Krismer, Anja Beierfuss, Gregory Effantin, et al. “HIV Neutralizing Antibodies Induced by Native-like Envelope Trimers Incorporated Into a Rhabdoviral Vector Vaccine.” In Aids Research and Human Retroviruses, 34:324–324. MARY ANN LIEBERT, INC, 2018.Link to Item
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Pollara, Justin, Dorothy I. Jones, Tori Huffman, Maria Dennis, Grace Li, Derrick Goodman, R Whitney Edwards, et al. “Bridging Vaccine-induced Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” In Aids Research and Human Retroviruses, 34:129–129. MARY ANN LIEBERT, INC, 2018.Link to Item
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Verkoczy, Laurent, Chuancang Jiang, Raiees Andrabi, Jinsong Zhang, Amanda Newman, Devin Sok, Ge Song, et al. “Mechanistic Insights Into Vaccine Induction of V2 Apex-directed, Heterologous Tier 2 Neutralizing Responses in CH103 UCA Knock-in Mice.” In Aids Research and Human Retroviruses, 34:110–110. MARY ANN LIEBERT, INC, 2018.Link to Item
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Felber, Barbara K., Antonio Valentin, Eric Ramirez Salazar, Rami Doueiri, Margherita Rosati, Xintao Hu, Candido Alicea, et al. “DNA and Protein Co-delivery Vaccines Using TLR-4-based Adjuvants Induce Potent Immune Responses Able to Delay Heterologous SIV Acquisition.” In Aids Research and Human Retroviruses, 32:67–67. MARY ANN LIEBERT, INC, 2016.Link to Item
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Rademeyer, Cecilia, Bette Korber, Michael S. Seaman, Elena E. Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J. Sheward, et al. “Features of Recently Transmitted HIV-1 Clade C Viruses That Impact Antibody Recognition: Implications for Active and Passive Immunization.” In Aids Research and Human Retroviruses, 32:261–261. MARY ANN LIEBERT, INC, 2016.Link to Item
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Reddy, Pradeep B. J., Sailaja Gangadhara, Traci Legere, Brenda Wehrle, Yevgeniy Kovalenkov, Lori M. Spicer, Madhavi Kaja, et al. “Effects of gp140 Protein Booster Immunizations to DNA/MVA SHIV Vaccine on Immunogenicity and Protection against Intravaginal Tier-2 SHIV Challenges.” In Aids Research and Human Retroviruses, 32:347–347. MARY ANN LIEBERT, INC, 2016.Link to Item
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Tuero, Iskra, Venkatramanan Mohanram, Thomas Musich, Diego Vargas-Inchaustegui, Thorsten Demberg, Irene Kalisz, V. S. Kalyanaraman, et al. “VACCINE-INDUCED MUCOSAL B CELLS ARE CORRELATED WITH DELAYED SIVMAC251 ACQUISITION FOLLOWING RECTAL CHALLENGE OF FEMALE BUT NOT MALE RHESUS MACAQUES.” In Journal of Medical Primatology, 44:341–341. WILEY-BLACKWELL, 2015.Link to Item
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Valentin, Antonio, Jinyao Li, Rashmi Jalah, Vainav Patel, Margherita Rosati, Viraj Kulkarni, Candido Alicea, et al. “DNA AND PROTEIN CO-IMMUNIZATION IMPROVES THE MAGNITUDE, LONGEVITY, AND MUCOSAL DISSEMINATION OF IMMUNE RESPONSES.” In Journal of Medical Primatology, 44:341–341. WILEY-BLACKWELL, 2015.Link to Item
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Fourati, S., M. Vaccari, S. N. Gordon, L. Schifanella, M. Cameron, B. F. Keele, X. Shen, et al. “Modulation of RAS Pathways as a Biomarker of Protection against HIV and as a Means to Improve Vaccine Efficacy.” In Aids Res Hum Retroviruses, 30 Suppl 1:A99, 2014. https://doi.org/10.1089/aid.2014.5182b.abstract.Full Text Link to Item
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Pavlakis, G. N., J. Li, A. Valentin, R. Jalah, V. Patel, M. Rosati, V. Kulkarni, et al. “DNA and Protein Co-immunization Improves the Magnitude, Longevity, and Mucosal Dissemination of Immune Responses.” In Aids Res Hum Retroviruses, 30 Suppl 1:A63–64, 2014. https://doi.org/10.1089/aid.2014.5115.abstract.Full Text Link to Item
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Pavlakis, George N., Rashmi Jalah, Jinyao Li, Antonio Valentin, Margherita Rosati, Vainav Patel, Viraj Kulkarni, et al. “OPTIMIZATION OF SYSTEMIC AND MUCOSAL IMMUNE RESPONSES TO SIV AND HIV-1 ANTIGENS USING DIFFERENT PROTOCOLS OF DNA AND PROTEIN IMMUNIZATION IN MACAQUES.” In Journal of Medical Primatology, 43:410–410. WILEY-BLACKWELL, 2014.Link to Item
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Vaccari, M., S. N. Gordon, S. Fourati, L. Schifanella, M. Cameron, B. F. Keele, X. Shen, et al. “Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition.” In Aids Res Hum Retroviruses, 30 Suppl 1:A64–65, 2014. https://doi.org/10.1089/aid.2014.5117.abstract.Full Text Link to Item
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Moody, M. A., D. Easterhoff, T. C. Gurley, J. F. Whitesides, D. J. Marshall, A. Foulger, K. E. Lloyd, et al. “Induction of Antibodies with Long Variable Heavy Third Complementarity Determining Regions by Repetitive Boosting with AIDSVAX® B/E in RV144 Vaccinees.” In Aids Res Hum Retroviruses, 30 Suppl 1:A36, 2014. https://doi.org/10.1089/aid.2014.5057a.abstract.Full Text Link to Item
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Sarzotti-Kelsoe, M., X. Daniell, C. A. Todd, M. Bilska, A. Martelli, C. LaBranche, L. G. Perez, et al. “Optimization and validation of a neutralizing antibody assay for HIV-1 in A3R5 cells.” In Journal of Immunological Methods, 2014.Open Access Copy
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Bonsignori, M., K. Wiehe, R. M. Lynch, S. K. Grimm, D. M. Kozink, K. Hwang, J. A. Eudailey, et al. “Isolation and Characterization of an Autoreactive CD4bs Broad Neutralizing Antibody from a Chronic HIV-1 Controller with Systemic Lupus Erythematosus.” In Aids Research and Human Retroviruses, 29:A45–46. MARY ANN LIEBERT, INC, 2013.Link to Item
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Chege, G. K., D. C. Montefiori, S. Barnett, C. M. Gray, W. A. Burgers, T. L. Muller, E. G. Shephard, C. Williamson, G. Ferrari, and A. Williamson. “A Combined Saavi MVA-C and Novartis Gp140 Env Protein Vaccine Boost Elicits Robust HIV Cellular and Humoral Responses in a Nonhuman Primate Model.” In Aids Research and Human Retroviruses, 29:A39–A39. MARY ANN LIEBERT, INC, 2013.Link to Item
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Chen, Y., J. Zhang, H. Bouton-Verville, A. Newman, S. Xia, H. Liao, D. C. Montefiori, et al. “Lipid Components in MPER-Based Immunization Regimens Are Critical for Inducing Broadly Neutralizing Antibody Responses in 2F5 and 4E10 Knockin Mice.” In Aids Research and Human Retroviruses, 29:A20–A20. MARY ANN LIEBERT, INC, 2013.Link to Item
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Gao, F., M. Bonsignori, H. Liao, A. Kumar, S. Xia, F. Cai, X. Lu, et al. “Multiple Pathways of HIV-1 Autologous Neutralizing Antibodies Cooperate to Drive CD4 Binding Site Broadly Neutralizing Antibody Responses.” In Aids Research and Human Retroviruses, 29:A186–A186. MARY ANN LIEBERT, INC, 2013.Link to Item
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Gordon, S. N., M. Vaccari, M. N. Doster, N. P. Liyanage, P. Pegu, L. Schifanella, F. Caccuri, et al. “Priming with Adenovirus26 Vaccines Affects ALVAC-SIV/gp120 Vaccine Efficacy Tested in a SIVmac251 Challenge Model Performed One-Month Post-Vaccination.” In Aids Research and Human Retroviruses, 29:A39–A39. MARY ANN LIEBERT, INC, 2013.Link to Item
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Pavlakis, G. N., R. Jalah, J. Li, A. Valentin, M. Rosati, V. Patel, V. Kulkarni, et al. “Optimization of Systemic and Mucosal Immune Responses to SIV and HIV-1 Antigens Using Different Protocols of DNA and Protein Immunization in Macaques.” In Aids Research and Human Retroviruses, 29:A19–A19. MARY ANN LIEBERT, INC, 2013.Link to Item
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Perez, L. G., and D. C. Montefiori. “Env Binding to the alpha 4 beta 7 Integrin Complex Is Not a General Property of Most HIV-1 Variants.” In Aids Research and Human Retroviruses, 29:A100–A100. MARY ANN LIEBERT, INC, 2013.Link to Item
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Pollara, J., M. Bonsignori, M. Moody, S. Alam, K. Hwang, T. C. Gurley, D. M. Kozink, et al. “Heterogeneity of Anti-V2 ADCC Ab Responses and Implications for Vaccine Development.” In Aids Research and Human Retroviruses, 29:A41–A41. MARY ANN LIEBERT, INC, 2013.Link to Item
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Rolland, M., P. T. Edlefsen, R. Gottardo, D. C. Montefiori, S. Zolla-Pazner, A. Moody, L. H. Liao, et al. “Genetic and Immunological Evidence for a Role of Env-V3 Antibodies in the RV144 Trial.” In Aids Research and Human Retroviruses, 29:A168–A168. MARY ANN LIEBERT, INC, 2013.Link to Item
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Vaccari, M., S. N. Gordon, M. Doster, N. Liynage, P. Pegu, L. Schifanella, B. F. Keele, et al. “Protection from SIVmac251 Acquisition by an ALVAC/SIV/gp120 Regimen Is Not Improved by the Increase of Anti-Envelope Antibodies and T Cell Responses.” In Aids Research and Human Retroviruses, 29:A34–A34. MARY ANN LIEBERT, INC, 2013.Link to Item
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Williams, W. B., K. Jones, P. Liu, A. M. Trama, K. Seaton, M. A. Moody, N. Vandergrift, et al. “Antibody Repertoire Induced by the Multiclade (Env A, B, C) HIV-1 DNA Prime, rAd5 Boost VRC Vaccine.” In Aids Research and Human Retroviruses, 29:A9–A9. MARY ANN LIEBERT, INC, 2013.Link to Item
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Montefiori, David C. “Magnitude, Breadth and Duration of HIV-1 Vaccine-Elicited Neutralizing Antibody Responses.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 62:51–51. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Pavlakis, George N., Rashmi Jalah, Antonio Valentin, Margherita Rosati, Vainav Patel, Viraj Kulkarni, Candido Alicea, et al. “Comparison of systemic and mucosal responses after DNA and protein co-immunization.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 62:56–56. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Alexander, J., M. Gurwith, J. Mendy, L. Vang, D. Manayani, J. Avanzini, B. Guenther, et al. “Development of a HIV-1 vaccine using an orally-administered, replication-competent adenovirus serotype 4 vector expressing Env clade C glycoprotein.” In Retrovirology, Vol. 9. BIOMED CENTRAL LTD, 2012.Link to Item
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Sholukh, A. M., N. B. Siddappa, V. Shanmuganathan, S. K. Lakhashe, R. A. Rasmussen, J. D. Watkins, H. K. Vyas, et al. “Passive immunization with polyclonal anti-SHIV IgG: partial protection or increased acquisition of heterologous tier 2 SHIV - depending on IgG dose.” In Retrovirology, Vol. 9. BIOMED CENTRAL LTD, 2012.Link to Item
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Bonsignori, M., J. Pollara, M. A. Moody, T. B. Kepler, X. Chen, T. C. Gurley, D. M. Kozink, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial preferentially use the VH1 gene family.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p78.Full Text
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Montefiori, D. C., Y. Huang, S. Karuna, M. Allen, N. Kochar, S. Chappuis, J. Gaillard, et al. “rAd5/NYVAC-B is superior to NYVAC-B/rAd5 and is dependent on rAd5 dose for neutralizing antibody responses against HIV-1.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p132.Full Text
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Moody, M., M. S. Drinker, T. C. Gurley, J. D. Amos, J. A. Eudailey, L. C. Armand, R. Parks, et al. “Isolation of a clonal lineage of IgA broadly neutralizing antibodies from a chronically infected Tanzanian subject.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o35.Full Text
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Williams, W. B., K. Jones, A. Krambrink, D. Grove, P. Liu, N. L. Yates, M. A. Moody, et al. “Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o55.Full Text
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Alpert, M. D., J. D. Harvey, W. J. Neidermyer, Y. Huang, D. Morris, L. Harris, H. Gao, et al. “ADCC Titers to HIV-Infected Cells Are Detectable in the Majority of Vaccine Recipients in the RV144 Trial.” In Aids Research and Human Retroviruses, 27:A20–21. MARY ANN LIEBERT INC, 2011.Link to Item
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Brown, B. K., L. Wieczorek, G. Kijak, K. Lombardi, J. Currier, M. Wesberry, C. Ochsenbauer, et al. “Influence of NK Cells and NK Cell Receptor Polymorphisms in the Assessment of HIV-1 Neutralization.” In Aids Research and Human Retroviruses, 27:A17–A17. MARY ANN LIEBERT INC, 2011.Link to Item
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Hu, X., K. Hong, C. Zhao, H. Gao, K. M. Greene, Y. Zheng, L. Ren, Y. Ruan, D. C. Montefiori, and Y. Shao. “Profiles of Neutralizing Antibody Responses in Chronically HIV-1 CRF07_BC Infected Intravenous Drug Users in Western China.” In Aids Research and Human Retroviruses, 27:A46–47. MARY ANN LIEBERT INC, 2011.Link to Item
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Jalah, R., V. Patel, V. Kulkarni, A. Valentin, C. Alicea, M. Rosati, A. von Gegerfelt, et al. “DNA and Protein Vaccination Confers Protection Upon Mucosal Challenge with Heterologous SIVsmE660.” In Aids Research and Human Retroviruses, 27:A24–A24. MARY ANN LIEBERT INC, 2011.Link to Item
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Lacerda, M., P. L. Moore, N. Ngandu, E. S. Gray, K. Wibmer, M. Nonyane, D. Sheward, et al. “Identification of Amino Acid Residues in HIV-1 Envelope Targeted by Plasma Broadly Neutralizing Antibodies using Evolutionary Models.” In Aids Research and Human Retroviruses, 27:A15–16. MARY ANN LIEBERT INC, 2011.Link to Item
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Lynch, R. M., M. K. Louder, L. Tran, Z. Yang, G. Tomaras, M. Cohen, E. S. Gray, et al. “Detection of CD4-Binding Site Antibodies in Three HIV-1 Seroconverter Cohorts.” In Aids Research and Human Retroviruses, 27:A47–A47. MARY ANN LIEBERT INC, 2011.Link to Item
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Ferrari, G., J. Pollara, D. Kozink, T. Harms, M. Drinker, S. Freel, M. A. Moody, et al. “Mapping of ADCC Activity: The A32 Conformational C1 Epitope is a Dominant Target for ADCC Antibodies in Chronically HIV-1 Infected Subjects.” In Aids Research and Human Retroviruses, 27:A66–A66. MARY ANN LIEBERT INC, 2011.Link to Item
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Lakhashe, Samir K., Wendy Wang, Nagadenahalli B. Siddappa, Girish Hemashettar, Patricia Polacino, Shiu-Lok Hu, Francois Villinger, et al. “VACCINATION AGAINST MUCOSAL CHALLENGES WITH HETEROLOGOUS R5 CLADE C SHIV: PREVENTION OF INFECTION AND CORRELATES OF PROTECTION.” In Journal of Medical Primatology, 40:267–68. WILEY-BLACKWELL, 2011.Link to Item
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Amou’ou, G Fouda, A. S. Perelson, N. K. Vaidya, G. M. Shaw, and D. C. Montefiori. “Decrease in the Ratio of Infectious to Total Virions During Acute HIV-1 Infection.” In Aids Research and Human Retroviruses, 26:A13–A13. MARY ANN LIEBERT INC, 2010.Link to Item
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Bonsignori, M., K. Hwang, X. Chen, C. Tsao, M. Bilska, W. Fang, D. Marshall, et al. “Immunoregulation of HIV-1 broadly neutralizing antibody responses: deciphering maturation paths for antibody induction.” In Aids Research and Human Retroviruses, 26:A153–A153. MARY ANN LIEBERT INC, 2010.Link to Item
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Gegerfelt, A. von, A. Valentin, C. Alicea, K. K. Van Rompay, M. L. Marthas, D. C. Montefiori, G. N. Pavlakis, and B. K. Felber. “SIV-Specific Cytotoxic CD4+T Cells and Humoral Responses Control Rebounding Viremia in CD8-Depleted Macaques Infected with Rev-Independent SIV.” In Aids Research and Human Retroviruses, 26:A112–A112. MARY ANN LIEBERT INC, 2010.Link to Item
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Geonnotti, A. R., S. Gnanakaran, M. G. Daniels, T. Bhattacharya, A. Lapedes, B. Korber, and D. C. Montefiori. “Computationally identified mutations suspected to cause gp120 charge inversion and gp41-mediated allosteric effects impact IgG1b12 susceptibility.” In Aids Research and Human Retroviruses, 26:A27–A27. MARY ANN LIEBERT INC, 2010.Link to Item
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Jalah, R., V. Patel, V. Kulkarni, A. Valentin, C. Alicea, M. Rosati, A. von Gegerfelt, et al. “Improvement of humoral immune responses in macaques using DNA/viral particle combination vaccine.” In Aids Research and Human Retroviruses, 26:A118–A118. MARY ANN LIEBERT INC, 2010.Link to Item
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Karnasuta, C., R. McLinden, M. de Souza, N. Karasavva, S. Tovanabutra, A. Laurence-Chenine, E. Sanders-Buell, et al. “Magnitude and Breadth of the Neutralizing Antibody Response in RV144.” In Aids Research and Human Retroviruses, 26:A161–A161. MARY ANN LIEBERT INC, 2010.Link to Item
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Lai, R. P., P. Tonks, D. J. Seilly, A. K. Dey, P. Sarkar, D. C. Montefiori, M. S. Seaman, et al. “Neutralizing antibody responses to HIV-1 are dependent on conformational integrity of gp140 immunogens.” In Aids Research and Human Retroviruses, 26:A50–A50. MARY ANN LIEBERT INC, 2010.Link to Item
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Patel, V., V. Kulkarni, R. Jalah, A. Valentin, C. Alicea, M. Rosati, A. von Gegerfelt, et al. “Improved DNA vaccination achieves long-lasting immune responses in macaques.” In Aids Research and Human Retroviruses, 26:A120–21. MARY ANN LIEBERT INC, 2010.Link to Item
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Pavlakis, G. N., A. Valentin, M. Rosati, V. Patel, R. Jalah, V. Kulkarni, C. Alicea, et al. “DNA and combination vaccines achieve high levels of long lasting and protective cellular and humoral responses.” In Aids Research and Human Retroviruses, 26:A123–24. MARY ANN LIEBERT INC, 2010.Link to Item
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Perez, L. G., B. F. Haynes, and D. C. Montefiori. “Evidence against phagocytosis in Fc gamma RI-mediated HIV neutralization by MPER antibodies in TZM-bl cells.” In Aids Research and Human Retroviruses, 26:A152–A152. MARY ANN LIEBERT INC, 2010.Link to Item
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Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, G. Fouda, R. Schutte, X. Shen, et al. “New broadly neutralizing human monoclonal antibodies targeting the 2F5 epitope.” In Aids Research and Human Retroviruses, 26:A14–15. MARY ANN LIEBERT INC, 2010.Link to Item
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Siddappa, Nagadenahalli B., Klemens Wassermann, Wendy Wang, Jennifer Watkins, Victor G. Kramer, Samir Lakhashe, Michael Santosuosso, et al. “NATURAL EVOLUTION OF CLADE C SHIV NEUTRALIZATION SENSITIVITY FROM TIER 1 TO TIER 2 IS LINKED TO DIFFERENCES IN V1 AND V2 LOOP SEQUENCES IN ENV.” In Journal of Medical Primatology, 39:268–268. WILEY-BLACKWELL, 2010.Link to Item
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Brown, B. K., K. Lombardi, M. Bryson, J. Currier, D. Thelian, L. Wieczorek, G. Kijak, et al. “P04-12. Characterization of leukopak PBMC phenotypes and biotypes for optimal performance in HIV-1 neutralization assays.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P40.Full Text
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Carrico, C. T., E. Lagerquist, E. Boni, Y. A. Ban, C. Bretz, K. Ellingson, O. Kalyuzhniy, et al. “P05-12. A computationally designed immunogen elicits potent anti-V3 neutralizing antibodies.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P88.Full Text
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Chung, H., L. Galmin, J. Suschak, D. Weiss, L. Finke, D. Montefiori, and R. Pal. “P03-10. Induction of neutralizing antibodies in Rhesus macaques following mucosal challenge with R5 tropic SHIV162P3 isolate.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P27.Full Text
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Eller, L., B. Ouma, P. Oballah, M. A. Eller, M. S. de Souza, F. Wabwire-Mangen, O. Laeyendecker, et al. “P04-28. Breadth and magnitude of neutralizing antibody responses in subjects infected with HIV-1 subtype D or recombinants in Rakai district, Uganda.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P56.Full Text
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Gnanakaran, G., T. Bhattacharya, M. Daniels, A. Lapedes, F. Gao, A. Kumar, M. Li, et al. “P04-54 LB. Genetic signature analysis identifies the CD4i region of gp120 as a determinant of broadly NAb responses in HIV-1-infected individuals.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P394.Full Text
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Njai, H. F., K. Tomusange, B. Sokolik-Wolak, D. Montefiori, S. Balla, G. Vanham, J. Levin, et al. “P04-11. Prevalence of neutralizing antibody responses in chronic clades A and D human immunodeficiency virus type 1 (HIV-1) infections.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P39.Full Text
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Perez, L. G., M. R. Costa, and D. C. Montefiori. “P11-07. Characterization of a new TZM-bl cell line that expresses human FcαR(CD89).” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P152.Full Text
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Scarlatti, G., J. Alcami, V. Bongertz, E. Fenyö, A. Heath, L. Heyndrickx, H. Holmes, et al. “P04-18. Comparison of HIV neutralization assays for use in vaccine research and clinical trials, phase II: Results from the NeutNet working group.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P46.Full Text
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Shen, X., M. Dennison, F. Gao, D. C. Montefiori, L. Verkoczy, B. Haynes, M. Alam, and G. Tomaras. “OA021-04. HIV-1 gp41 envelope MPER mutation altered epitope conformation in lipid and increased sensitivity to 2F5 and 4E10 neutralizing antibodies.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-O16.Full Text
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Todd, C. A., X. Yu, D. A. Ozaki, K. M. Greene, H. Gao, B. Wood, M. Wang, P. Gilbert, D. C. Montefiori, and M. Sarzotti-Kelsoe. “P15-04. Development and implementation of an international proficiency testing program for a neutralizing antibody assay for HIV-1 in TZM-bl cells.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P205.Full Text
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Wieczorek, L., B. K. Brown, M. Wesberry, C. Ochsenbauer-Jambor, J. C. Kappes, N. Lora, A. Gillis, et al. “P04-23. HIV-1 neutralization is impacted by the PBMC donor used for both virus growth and target cells, and the effects are neutralization reagent-specific.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P51.Full Text
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Yates, Nicole L., Judith Lucas, Rob Parks, Vicki C. Ashley, Glenn Overman, David C. Montefiori, Kent J. Weinhold, et al. “142 HIV Frequently Elicits Mucosal and Plasma Env-Specific IgA With a Rapid Initial Decline In Acute Infection.” In Jaids Journal of Acquired Immune Deficiency Syndromes, Vol. 51. Ovid Technologies (Wolters Kluwer Health), 2009. https://doi.org/10.1097/01.qai.0000351099.78513.42.Full Text
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Borges, A Rosa, E. Sanders-Buell, L. Wieczorek, J. C. O’Toole, B. K. Brown, M. Bilska, M. Li, et al. “Recombination of HIV-1 gp160 Clones with Viral Backbone DNA through Co-transfection to Produce Pseudoviruses can Create Replication Competent Viruses.” In Aids Research and Human Retroviruses, 24:47–48. MARY ANN LIEBERT INC, 2008.Link to Item
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Hinz, A., H. Quendler, H. Katinger, M. Seaman, G. Schoehn, B. Ferko, G. Stiegler, D. C. Montefiori, and W. Weissenhorn. “Immunogenicity and Neutralization Properties of a Trimeric MPER Containing gp41 Antigen.” In Aids Research and Human Retroviruses, 24:97–97. MARY ANN LIEBERT INC, 2008.Link to Item
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Kulkarni, S. S., A. Lapedes, H. Tang, G. Gnanakaran, M. G. Daniels, M. Zhang, M. Li, et al. “Highly Complex Neutralization Determinants on a Monophyletic Lineage of Newly Transmitted Subtype C HIV-1 Env Clones from India.” In Aids Research and Human Retroviruses, 24:48–49. MARY ANN LIEBERT INC, 2008.Link to Item
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Moody, M. A., M. K. Plonk, L. Fuller, H. Liao, S. Xia, M. S. Drinker, T. C. Gurley, et al. “Anti-lipid Human Monoclonal Antibodies Inhibit HIV-1 Infection of PBMC by Binding to Host Cells.” In Aids Research and Human Retroviruses, 24:13–13. MARY ANN LIEBERT INC, 2008.Link to Item
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Nishiyama, Y., S. Planque, Y. Mitsuda, B. Jena, M. Salas, L. Jin, J. Symersky, et al. “Covalent gp120 Immunization: Induction of Neutralizing Monoclonal Antibodies but Failure to Enhance Vaccine-Relevant Polyclonal Antibody Activity.” In Aids Research and Human Retroviruses, 24:56–56. MARY ANN LIEBERT INC, 2008.Link to Item
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Perez, L. G., C. A. Todd, and D. C. Montefiori. “Enhanced Neutralization of HIV-1 by gp41 MPER-Specific Antibodies in Cells that Express Fcg Receptors.” In Aids Research and Human Retroviruses, 24:11–11. MARY ANN LIEBERT INC, 2008.Link to Item
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Planque, S., M. Salas, M. A. Escobar, M. Morris, B. Jena, Y. Mitsuda, Y. Nishiyama, et al. “Exceptionally Potent, Broadly-Neutralizing IgAs from Survivors of Prolonged HIV Infection.” In Aids Research and Human Retroviruses, 24:55–55. MARY ANN LIEBERT INC, 2008.Link to Item
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Vaine, M., S. Wang, E. T. Crooks, P. Jiang, D. C. Montefiori, J. Binley, and S. Lu. “Improved Induction of Antibodies against Key Neutralizing Epitopes by HIV-1 gp120 DNA Prime-Protein Boost Compared to gp120 Protein Only Vaccination.” In Aids Research and Human Retroviruses, 24:45–45. MARY ANN LIEBERT INC, 2008.Link to Item
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Lai, L., D. C. Montefiori, L. Chennareddi, and H. L. Robinson. “Identification of ENVS that preferentially bind the cross-reactive neutralizing Ab in chronic patient sera.” In Journal of Medical Primatology, 36:296–296. BLACKWELL PUBLISHING, 2007.Link to Item
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Lai, Lilin, Dalma Vodros, Francois Villinger, David C. Montefiori, Lazarus Ofielu, Lakshmi Chennareddi, Rama R. Amara, and Harriet L. Robinson. “GM-CSF as an adjuvant for protective immune responses.” In Journal of Medical Primatology, 36:328–29. BLACKWELL PUBLISHING, 2007.Link to Item
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Sestak, Karol, Mayra A. Cantu, Wei Zhao, Marcelo J. Kuroda, David C. Montefiori, Ronald S. Veazey, Preston A. Marx, John D. Clements, Andrew A. Lackner, and Karin Lovgren-Bengtsson. “Mucosal aids vaccine delivered to rhesus macaques via immuno-stimulating complexes induces low levels of virus-neutralizing antibodies and cytotoxic T cell responses that are rapidly expanded upon challenge with simian-human immunodeficiency viruses (sHIVs).” In Journal of Medical Primatology, 35:315–315. BLACKWELL PUBLISHING, 2006.Link to Item
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Clark, K Reed, Jianchao Zhang, David C. Montefiori, and Philip R. Johnson. “586. Anti-HIV-1 Neutralizing Antibody Gene Delivery to Rhesus Macaques and Rodents: A Novel Vaccination Approach.” In Molecular Therapy, 13:S226–S226. Elsevier BV, 2006. https://doi.org/10.1016/j.ymthe.2006.08.660.Full Text
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Liao, H. X., D. C. Montefiori, D. D. Patel, D. M. Lee, W. K. Scott, M. Pericak-Vance, and B. F. Haynes. “Association of the CCR5D32 mutation with a functional polymorphism of CD45RA.” In Faseb Journal, 14:A983–A983. FEDERATION AMER SOC EXP BIOL, 2000.Link to Item
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Johnson, P. R., N. L. Davis, I. J. Caley, K. W. Brown, M. R. Betts, D. M. Irlbeck, K. McGrath, et al. “A novel SIV vaccine based on Venezuelan equine encephalitis virus (VEE) replicons.” In Pediatric Research, 47:265A-265A. INT PEDIATRIC RESEARCH FOUNDATION, INC, 2000.Link to Item
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Montefiori, D. C., and T. G. Evans. “Toward an HIV type 1 vaccine that generates potent, broadly cross-reactive neutralizing antibodies.” In Aids Res Hum Retroviruses, 15:689–98, 1999. https://doi.org/10.1089/088922299310773.Full Text Link to Item
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Davis, N. L., K. W. Brown, I. J. Caley, G. H. MacDonald, D. M. Irlbeck, M. R. Betts, P. Pushko, et al. “A multicomponent SIV vaccine delivered by Venezuelan equine encephalitis virus vectors.” In 11e Colloque Des Cent Gardes, edited by M. Girard and B. Dodet, 209–14. EDITIONS SCIENTIFIQUES ET MEDICALES ELSEVIER, 1998.Link to Item
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Montefiori, D. C., B. F. Haynes, B. Moss, K. A. Reimann, H. X. Liao, J. Y. Zhou, M. Bilska, D. P. Bolognesi, N. L. Letvin, and P. L. Earl. “Design of an HIV-1 vaccine that will raise neutralizing antibodies to primary isolates.” In 11e Colloque Des Cent Gardes, edited by M. Girard and B. Dodet, 131–36. EDITIONS SCIENTIFIQUES ET MEDICALES ELSEVIER, 1998.Link to Item
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Robinson, H. L., D. C. Montefiori, P. R. Johnson, S. Lu, T. A. Rizvi, K. Manson, and M. Wyand. “Protective efficacy of DNA primes combined with protein or recombinant fowl pox boosts for a SHIV-challenge.” In 11e Colloque Des Cent Gardes, edited by M. Girard and B. Dodet, 277–80. EDITIONS SCIENTIFIQUES ET MEDICALES ELSEVIER, 1998.Link to Item
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Hirsch, V. M., D. AdgerJohnson, B. Campbell, S. Goldstein, C. Brown, W. R. Elkins, and D. C. Montefiori. “A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3.” In Vaccines 97 Molecular Approaches to the Control of Infectious Diseases, edited by F. Brown, D. Burton, P. Doherty, J. Mekalanos, and E. Norrby, 285–89. COLD SPRING HARBOR LABORATORY PRESS, 1997.Link to Item
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Hu, S. L., J. Klaniecki, B. M. Travis, T. Wrey, S. Pennathur, D. C. Montefiori, J. L. Thompson, M. B. Agy, L. Kuller, and W. R. Morton. “Immunization with HIV-1 gp160 by the ''prime and boost'' regimen protects macaques against SHIV HXBc2 challenge.” In Vaccines 97 Molecular Approaches to the Control of Infectious Diseases, edited by F. Brown, D. Burton, P. Doherty, J. Mekalanos, and E. Norrby, 291–98. COLD SPRING HARBOR LABORATORY PRESS, 1997.Link to Item
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Montefiori, D. C. “Role of complement in HIV and SIV pathogenesis and immunity.” In Symposium in Immunology V, edited by M. M. Eibl, C. Huber, H. H. Peter, and U. Wahn, 31–53. SPRINGER-VERLAG BERLIN, 1996.Link to Item
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MONTEFIORI, D. C., B. VASUDEVAN, L. N. MARTIN, G. PANTALEO, A. S. FAUCI, and J. ZHOU. “ANTIBODIES THAT FORM IMMUNE-COMPLEXES CAPABLE OF BINDING COMPLEMENT RECEPTOR TYPE-1 (CR1/CD35) AS A CORRELATE OF IMMUNITY IN HIV-1 AND SIV INFECTION AND VACCINATION.” In Journal of Cellular Biochemistry, 223–223. WILEY-LISS, 1995.Link to Item
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MONTEFIORI, D. C. “WHAT IS THE FATE OF COMPLEMENT-OPSONIZED HIV.” In Aids Research and Human Retroviruses, 11:S134–S134. MARY ANN LIEBERT INC PUBL, 1995.Link to Item
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REIMANN, K. A., J. T. LI, G. VOSS, C. LEKUTIS, K. TENNERRACZ, P. RACZ, W. LIN, et al. “AN ENV GENE DERIVED FROM A PRIMARY HIV-1 ISOLATE CONFERS HIGH IN-VIVO REPLICATIVE CAPACITY TO A CHIMERIC SIMIAN/HUMAN IMMUNODEFICIENCY VIRUS IN RHESUS-MONKEYS.” In Aids Research and Human Retroviruses, 11:S93–S93. MARY ANN LIEBERT INC PUBL, 1995.Link to Item
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RUPRECHT, R. M., S. AYEHUNIE, T. W. BABA, L. AN, V. LISKA, D. PENNINCK, M. GREENE, and D. C. MONTEFIORI. “SIV PATHOGENESIS DURING ONTOGENY - THE VIRUS THRESHOLD HYPOTHESIS.” In Aids Research and Human Retroviruses, 11:S129–S129. MARY ANN LIEBERT INC PUBL, 1995.Link to Item
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MONTEFIORI, D. C., J. Y. ZHOU, J. T. ZHOU, and J. M. AHEARN. “BINDING OF HIV-1 TO THE C3B/C4B RECEPTOR, CR-1 (CD35), IN THE PRESENCE OF COMPLEMENT AND ANTIBODIES FROM INFECTED INDIVIDUALS AND GP160-VACCINATED VOLUNTEERS.” In Aids Research and Human Retroviruses, 10:S41–S41. MARY ANN LIEBERT INC PUBL, 1994.Link to Item
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MONTEFIORI, D. C., R. J. CORNELL, J. Y. ZHOU, J. T. ZHOU, V. M. HIRSCH, and P. R. JOHNSON. “MECHANISM OF RESISTANCE OF HIV-1 AND SIV TO COMPLEMENT LYSIS - THE ROLE OF ANTI-CELL ANTIBODIES IN VACCINE PROTECTION.” In Aids Research and Human Retroviruses, 10:S135–S135. MARY ANN LIEBERT INC PUBL, 1994.Link to Item
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MONTEFIORI, D. C., J. T. ZHOU, R. BUCCO, J. Y. ZHOU, L. A. CAVACINI, and M. R. POSNER. “V3-SPECIFIC NEUTRALIZING ANTIBODIES IN SERA FROM HIV-1 GP160-IMMUNIZED VOLUNTEERS BLOCK VIRUS ATTACHMENT AND ACT SYNERGISTICALLY WITH HUMAN MONOCLONAL-ANTIBODY TO THE CONFORMATION-DEPENDENT CD4 BINDING REGION OF GP120.” In Aids Research and Human Retroviruses, 9:S79–S79. MARY ANN LIEBERT INC PUBL, 1993.Link to Item
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MONTEFIORI, D. C., K. STEWART, D. SHAFF, J. Y. ZHOU, and J. M. AHEARN. “COMPLEMENT-MEDIATED BINDING OF HIV-1 TO CR-1 AND CR-2.” In Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 6:732–732. LIPPINCOTT-RAVEN PUBL, 1993.Link to Item
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MACON, W. R., S. C. LO, B. J. POIESZ, D. C. MONTEFIORI, M. S. DAWSON, T. E. MASON, P. R. MICHAEL, et al. “AIDS-LIKE ILLNESS ASSOCIATED WITH SYSTEMIC MYCOPLASMA-FERMENTANS INFECTION IN AN HIV-NEGATIVE HOMOSEXUAL MALE.” In Laboratory Investigation, 68:A105–A105. WILLIAMS & WILKINS, 1993.Link to Item
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MONTEFIORI, D. C., and P. R. JOHNSON. “COMPLEMENT-MEDIATED, INFECTION-ENHANCING ANTIBODIES IN HIV AND SIV INFECTION AND VACCINE TRIALS.” In Aids Research and Human Retroviruses, 8:940–940. MARY ANN LIEBERT INC PUBL, 1992.Link to Item
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JOHNSON, P. R., S. GOLDSTEIN, T. E. HAMM, S. KITOV, W. T. LONDON, J. L. GERIN, R. H. PURCELL, et al. “INACTIVATED WHOLE-VIRUS VACCINE DERIVED FROM A PROVIRAL DNA CLONE OF SIV INDUCES PROTECTION AGAINST CHALLENGE WITH CELL-FREE VIRUS BUT NOT INFECTED-CELLS.” In Vaccines 92 : Modern Approaches to New Vaccines Including Prevention of Aids, edited by F. BROWN, R. M. CHANOCK, H. S. GINSBURG, and R. A. LERNER, 95–102. COLD SPRING HARBOR LABORATORY PRESS, 1992.Link to Item
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HAAS, D. W., W. H. TETTELBACH, L. RATNER, D. C. MONTEFIORI, W. M. MITCHELL, and C. H. HAGEDORN. “ISOLATION AND QUANTITATION OF EIF-4E IN H-9 LYMPHOCYTES.” In Clinical Research, 37:A430–A430. SLACK INC, 1989.Link to Item
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SOBOL, R. W., K. KARIKO, S. W. LI, R. CHARUBALA, W. PFLEIDERER, D. C. MONTEFIORI, W. M. MITCHELL, and R. J. SUHADOLNIK. “HUMAN IMMUNODEFICIENCY VIRUS REVERSE-TRANSCRIPTASE - INHIBITION BY STRUCTURALLY AND STEREOCHEMICALLY MODIFIED ANALOGS OF 2-5A.” In Faseb Journal, 2:A830–A830. FEDERATION AMER SOC EXP BIOL, 1988.Link to Item
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MITCHELL, W. M., W. E. ROBINSON, W. H. CHAMBERS, S. S. SCHUFFMAN, D. C. MONTEFIORI, and T. N. OELTMAN. “NATURAL-KILLER-CELL INFECTION AND INACTIVATION INVITRO BY HTLV-III LAV.” In Journal of Cellular Biochemistry, 203–203. WILEY-LISS, 1986.Link to Item
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Preprints
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Luo, Sai, Jun Zhang, Alex J. B. Kreutzberger, Amanda Eaton, Robert J. Edwards, Changbin Jing, Hai-Qiang Dai, et al. “Humanized antibody potently neutralizes all SARS-CoV-2 variants by a novel mechanism.” Cold Spring Harbor Laboratory, June 26, 2022. https://doi.org/10.1101/2022.06.26.497634.Full Text
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