Eugene William Moretti

Research efforts are focused primarily in the area of functional genomics. Work has centered on investigating genetic polymorphisms in the surgical intensive care population that would predispose one to the development of the sepsis syndrome. As an extension of this work, there is ongoing investigation working to identify genetically susceptible populations at risk for developing various types of perioperative organ dysfunction. Parallel studies involve identification of a panel of biomarkers that would enable early diagnosis and intervention for those patients, both surgical and non-surgical that develop the sepsis syndrome. There is also active investigation in the human pharmacology laboratory in the department of anesthesiology involving the phase 1 testing of novel pharmaceutical agents in healthy volunteers.

Current Appointments & Affiliations

Professor of Anesthesiology · 2021 - Present Anesthesiology, General, Vascular, High Risk Transplant & Critical Care, Anesthesiology

Professor in the School of Nursing · 2014 - Present School of Nursing

Recent Publications

Erratum: The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.

Journal Article Anesth Analg · May 1, 2025 Full text Link to item Cite

The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.

Journal Article Anesth Analg · January 1, 2025 BACKGROUND: Obstructive sleep apnea is associated with increased dementia risk, yet its role in postoperative neurocognitive disorders is unclear. Here, we studied whether the severity of untreated obstructive sleep apnea is associated with the severity of ... Full text Link to item Cite

Cognitive and Cerebrospinal Fluid Alzheimer's Disease-related Biomarker Trajectories in Older Surgical Patients and Matched Nonsurgical Controls.

Conference Anesthesiology · May 1, 2024 BACKGROUND: Anesthesia and/or surgery accelerate Alzheimer's disease pathology and cause memory deficits in animal models, yet there is a lack of prospective data comparing cerebrospinal fluid (CSF) Alzheimer's disease-related biomarker and cognitive traje ... Full text Link to item Cite

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Recent Grants

Right Place, Right Time: Information Design to Support Decisions in Acute Care

ResearchCo Investigator · Awarded by Saint Alphonsus Regional Medical Center · 2015 - 2018

Toward intelligent display of health data: A qualitative study of use patterns

ResearchCo Investigator · Awarded by National Institutes of Health · 2011 - 2015

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Education, Training & Certifications

Duke University, School of Medicine · 2004 M.H.S.

Temple University · 1993 M.D.