Scholars@Duke
Nazish Khalid Hashmi

Nazish Khalid Hashmi

Assistant Professor of Anesthesiology
Anesthesiology, Cardiothoracic

Selected Publications

Blood or Fat? Differentiating Hemopericardium versus Epicardial Fat Using Focused Cardiac Ultrasound.

Journal Article Diagnostics (Basel) · April 15, 2024 Basic point-of-care ultrasound of the heart-also known as Focused Cardiac Ultrasound (FoCUS)-has emerged as a powerful bedside tool to narrow the differential diagnosis of causes of hypotension. The list of causes of hypotension that a FoCUS provider is ex ... Full text Link to item Cite

Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery.

Journal Article Circulation · October 24, 2023 BACKGROUND: Right ventricular failure (RVF) is a leading driver of morbidity and death after major cardiac surgery for advanced heart failure, including orthotopic heart transplantation and left ventricular assist device implantation. Inhaled pulmonary-sel ... Full text Open Access Link to item Cite

Prevention of contamination after endotracheal intubation using a dedicated sleeve.

Journal Article J Thorac Dis · September 28, 2023 BACKGROUND: Contamination of work surfaces by used laryngoscopes after endotracheal intubation is a serious infection control concern but no strategies are available to address it. We assessed if contamination of the surfaces after endotracheal intubation ... Full text Link to item Cite

The Quality Improvement Fellow: Educating on Making the Difference.

Journal Article A A Pract · September 1, 2023 The critical care medicine (CCM) fellowship is an opportunity for advanced anesthesiology trainees to refine their quality improvement (QI) skills. However, the short training period and inconsistent curricula make this challenging. The QI fellow (QIF) is ... Full text Link to item Cite

Pulmonary Vein Systolic Flow Reversal Seen With Severe Tricuspid Regurgitation.

Journal Article CASE (Phila) · July 2023 • Systolic PVF reversal is specific to severe MR. • We report systolic PVF reversal with severe TR and TS. • This may be caused by interatrial dependence due to elevated RAP. ... Full text Link to item Cite

The QI Fellow: Educating on Making the Difference

Conference ANESTHESIA AND ANALGESIA · 2023 Cite

Predictive capabilities of the European registry for patients with mechanical circulatory support right-sided heart failure risk score after left ventricular assist device implantation.

Journal Article J Cardiothorac Vasc Anesth · October 2022 OBJECTIVES: The prediction of right heart failure (RHF) after left ventricular assist device (LVAD) implantation remains a challenge. Recently, risk scores were derived from analysis of the European Registry for Patients with Mechanical Circulatory Support ... Full text Link to item Cite

Anesthetic Management in Adults with Congenital Heart Disease.

Journal Article Curr Cardiol Rep · March 2022 PURPOSE OF REVIEW: Adults with congenital heart disease (ACHD) are a complex and growing population that presents numerous challenges for anesthetic management. This review summarizes special considerations for anesthetic management in ACHD. RECENT FINDING ... Full text Open Access Link to item Cite

Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant: A Randomized Clinical Trial.

Journal Article JAMA Surg · January 1, 2022 IMPORTANCE: Inhaled nitric oxide (iNO) is commonly administered for selectively inhaled pulmonary vasodilation and prevention of oxidative injury after lung transplant (LT). Inhaled epoprostenol (iEPO) has been introduced worldwide as a cost-saving alterna ... Full text Open Access Link to item Cite

What Drugs Decrease Perioperative Bleeding?

Chapter · January 1, 2022 Perioperative bleeding can lead to increased patient morbidity and mortality. Patients should be assessed for anemia preope­ratively and optimized before elective surgery. Management of intraoperative bleeding should be guided by point-of-care, test-driven ... Full text Cite

Blood product transfusion and lung transplant outcomes: A systematic review.

Journal Article Clin Transplant · October 2021 The perioperative transfusion of blood products has long been linked to development of acute lung injury and associated with mortality across both medical and surgical patient populations.1,2 The need for blood product transfusion during and after lung tra ... Full text Link to item Cite

The Year in Perioperative Echocardiography: Selected Highlights from 2020.

Journal Article J Cardiothorac Vasc Anesth · September 2021 This article is the fifth of an annual series reviewing the research highlights of the year pertaining to the subspecialty of perioperative echocardiography for the Journal of Cardiothoracic and Vascular Anesthesia. The authors thank Editor-in-Chief Dr. Ka ... Full text Link to item Cite

Pneumonia: Hiding in Plain (Film) Sight.

Journal Article J Cardiothorac Vasc Anesth · November 2020 Herein, a case describing how point-of-care lung ultrasound was used to identify the source of progressive multiorgan failure when a chest x-ray and other routine tests failed to provide a conclusive answer is presented. The discussion after the case focus ... Full text Link to item Cite

Impact of Tricuspid Valve Repair for Moderate Tricuspid Regurgitation at the Time of Left Ventricular Assist Device Implantation on the Occurrence of Right Heart Failure

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Significant tricuspid regurgitation (TR) in patients undergoing durable left ventricular assist device (LVAD) implantation has been associated with increased incidence of right heart failure (RHF). There is great surgical practice variability rela ... Full text Cite

EUROMACS-RHF Risk Score and 3D Echocardiography as Predictors of Right Heart Failure after Left Ventricular Assist Device Implantation

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Right heart failure (RHF) after LVAD implantation is associated with significant morbidity and mortality. Recently, the EUROMACS-RHF risk score was developed to predict postoperative RHF in this setting. In a single-center analysis, we assessed th ... Full text Cite

Effects of a Goal Directed Transfusion Protocol on Severe Primary Graft Dysfunction after Lung Transplantation

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Transfusion during lung transplantation (LT) is linked to primary graft dysfunction (PGD) and worsened outcomes. Goal-directed protocols have improved outcomes in cardiac surgical populations and decreased transfusions in LT on cardiopulmonary byp ... Full text Cite

Patient-Reported Chronic Pain Outcomes After Lung Transplantation.

Journal Article Semin Cardiothorac Vasc Anesth · March 2020 Chronic pain after lung transplantation is a significant concern, in particular given the heterogeneity of the patient population and the challenges of achieving adequate pain control amid concerns related to complex immunosuppressant regimens and the poss ... Full text Link to item Cite

Durability and Efficacy of Tricuspid Valve Repair in Patients Undergoing Left Ventricular Assist Device Implantation.

Journal Article JACC Heart Fail · February 2020 OBJECTIVES: This study sought to determine the durability of tricuspid valve repair (TVr) performed concurrently with left ventricular assist device (LVAD) implantation and its association with the development of late right heart failure (RHF). BACKGROUND: ... Full text Open Access Link to item Cite

Unsuspected Coagulopathy: Epidural Hematoma in Lung Transplant Recipients: A Rare Complication

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Link to item Cite

Three-factor prothrombin complex concentrates for refractory bleeding after cardiovascular surgery within an algorithmic approach to haemostasis.

Journal Article Vox Sang · May 2019 BACKGROUND/OBJECTIVES: Prothrombin complex concentrates (PCC) are increasingly administered off-label in the United States to treat bleeding in cardiovascular surgical patients and carry the potential risk for acquired thromboembolic side-effects after sur ... Full text Open Access Link to item Cite

Renal Angina Is a Sensitive, but Nonspecific Identifier of Postcardiac Surgery Acute Kidney Injury.

Journal Article J Cardiothorac Vasc Anesth · February 2019 OBJECTIVES: Acute kidney injury (AKI) is a common complication of cardiac surgery, and early detection is difficult. This study was performed to determine the sensitivity, specificity, positive predictive value, negative predictive value, and statistical p ... Full text Link to item Cite

Emergency airway management

Chapter · January 1, 2018 Full text Cite

Methemoglobinemia with the use of benzocaine spray for awake fiberoptic intubation.

Conference Middle East J Anaesthesiol · October 2013 We report a case in which the use of benzocaine spray to facilitate awake fiber optic intubation (FOI) in a patient with a difficult airway caused methemoglobinemia intraoperatively. Local benzocaine was sprayed to numb the patient's airway for a total tim ... Link to item Cite

Biofilm accumulation on endotracheal tubes following prolonged intubation.

Journal Article J Laryngol Otol · March 2012 OBJECTIVE: To demonstrate that patients who have been intubated for prolonged periods of time will have an increased likelihood of developing bacterial biofilm on their endotracheal tubes. METHODS: We collected endotracheal tubes from patients at the time ... Full text Link to item Cite

Use of potassium-titanyl phosphate laser with flexible bronchoscope through a laryngeal mask airway in patients with difficult airways

Journal Article Operative Techniques in Otolaryngology - Head and Neck Surgery · June 1, 2011 Laryngeal lesions with difficult visualization and access require an alternative approach. Patients with difficult anatomy, anterior glottis, subglottic and upper tracheal lesions can present challenges for the anesthesiologist and surgeon. We describe a t ... Full text Cite

Quality of life and self-image in patients undergoing tracheostomy.

Conference Laryngoscope · 2010 OBJECTIVES: The objective of this study is to understand trends in the Quality of Life and Self Image in patients undergoing an elective tracheostomy for non-malignant laryngeotracheal pathologies. We will also discuss the relationship between quality of l ... Full text Link to item Cite

Antibiotic eluting chitosan glycerophosphate implant in the setting of acute bacterial sinusitis: a rabbit model.

Journal Article Am J Rhinol Allergy · 2010 BACKGROUND: Topical therapy offers the potential for treatment of sinonasal disease with minimal systemic side effects. Chitosan glycerophosphate (CGP) is a mucoadhesive polymer that can be used as an antibiotic eluting sinonasal implant in the treatment o ... Full text Link to item Cite

Extramedullary plasmacytoma of the nasopharynx treated with surgery and adjuvant radiation: Case report and review of the literature

Journal Article Laryngoscope · December 1, 2009 Objectives Extramedullary plasmacytoma (EMP) is a rare neoplasm of plasma cell origin that arises due to soft tissue infiltration of monoclonal plasma cells, in the absence of systemic disease. Although the head and neck is the most common location of EMP, ... Full text Cite

Laryngeal mask airway in laryngoscopies: a safer alternative for the difficult airway.

Journal Article ORL J Otorhinolaryngol Relat Spec · 2009 PURPOSE OF THE STUDY: This study was undertaken to highlight the method, usefulness and postoperative morbidity of using a laryngeal mask airway (LMA) to ventilate patients with difficult airways undergoing laryngeal procedures. PROCEDURES: Retrospective c ... Full text Link to item Cite

Laryngeal mask airway in laryngoscopies: A safer alternative for the difficult airway.

Journal Article Laryngoscope · January 1, 2009 Objectives: To identify patients with potentially difficult airways, and to determine the benefits and risks of ventilating such patients during laryngeal or upper tracheal procedures using a Laryngeal Mask Airway (LMA). Methods: The computer records of th ... Full text Cite

Chromatographic analysis of Hb S for the diagnosis of various sickle cell disorders in Pakistan.

Journal Article Ann Hematol · August 2008 Sickle cell disease remains a relatively obscure theme in research on haemoglobinopathies in Pakistan. Limited data is available regarding its prevalence in the country. The objective of our study was not only to estimate the frequency of different sickle ... Full text Link to item Cite

Identification of hemoglobin Q India (alpha 1-64 Asp-His) through ARMS-PCR. First report from Pakistan.

Journal Article Ann Hematol · May 2008 Various hemoglobinopathies have been reported from Pakistan excepting the rare ones like hemoglobin Q India. Our purpose of study was to identify the mutation (alpha 1 64 aspartate to histidine) through amplification restriction mutation system-polymerase ... Full text Link to item Cite