Mark Franklin Newman | Scholars@Duke

Mark Franklin Newman
Professor Emeritus of Anesthesiology

Best known for his work in assessing and improving clinical outcomes and quality of life following cardiac surgery, Dr. Mark Newman is President of the Duke Private Diagnostic Clinic (The Duke Faculty Practice Organization) and the Merel H. Harmel Professor of Anesthesiology at Duke University Medical Center. In addition, Dr. Newman developed the Multicenter Perioperative Outcomes Research Group of the Duke Clinical Research Institute established at Duke in 2001 to further the study of strategies to improve the outcomes of patients undergoing surgery and anesthesia. Dr. Newman has received funding from the National Institute on Aging, the American Heart Association, the National Heart, Lung and Blood Institute, the Anesthesia Patient Safety Foundation, and the International Anesthesia Research Society to investigate the impact of perioperative outcomes (neurocognitive decline, stroke, myocardial infarction, renal injury) on quantity and quality of life following cardiac surgery and resulting in numerous seminal publications in the New England Journal of Medicine , JAMA and Lancet. Dr. Newman is a popular lecturer and speaker, having appeared on NBC Nightly News and The Today Show and having spoken at more than 200 national and international meetings. Dr. Newman recently stepped down as the Chairman of the Duke University Department after 13 years to assume the role of PDC President. During Dr. Newman’s tenure the department grew exponentially doubling its clinical and academic funding, and developing many outstanding individuals that have gone on to leadership roles at Duke and other key academic institutions across the country.

Current Appointments & Affiliations

Professor Emeritus of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 2017
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 1997

Contact Information

200 Trent Drive, 1293 Orange Zone, Durham, NC 27710
Box 3810, 1293 Orange Zone, Duke South, Durham, NC 27710
newma005@mc.duke.edu (919) 681-6581

Background
Education, Training, & Certifications
- M.D., University of Louisville 1985
Duke Appointment History
- Professor of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 1999 - 2017
- Professor of Medicine, Medicine, Cardiology, Medicine 2003 - 2017
- Chair, Department of Anesthesiology, Anesthesiology, Clinical Science Departments 2001 - 2014
- Chief, Division of Anesthesiology Cardiac Service in the Department of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 1994 - 2006
- Associate Professor in Medicine, Medicine, Cardiology, Medicine 1999 - 2003
- Assistant Professor of Medicine, Medicine, Cardiology, Medicine 1995 - 1999
- Associate Professor of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 1996 - 1999
- Assistant Professor of Anesthesiology, Anesthesiology, Clinical Science Departments 1992 - 1996
Research
Selected Grants
- Lidocaine for Neuroprotection During Cardiac Surgery awarded by National Institutes of Health 2009 - 2016
- Cortical Beta-amyloid Levels and Neurocognitive Performance After Cardiac Surgery awarded by National Institutes of Health 2011 - 2014
- IPA-Jeffrey Taekman awarded by Veterans Administration Medical Center 2012
- IPA-Noa Segall awarded by Veterans Administration Medical Center 2012
- IPA-Eugene Hobbs awarded by Veterans Administration Medical Center 2008 - 2011
- IPA-Jeffrey Taekman awarded by Veterans Administration Medical Center 2008 - 2011
- IPA-Noa Segall awarded by Veterans Administration Medical Center 2008 - 2011
- Defining the Learning Curve in Research Trials awarded by National Institutes of Health 2004 - 2009
- PeriOperative Interventional Neuroprotection Trial POINT awarded by National Institutes of Health 2001 - 2008
- Creating, Implementing, and Sharing Best Practices for Clinical Trials Networks awarded by National Institutes of Health 2004 - 2008
- Genetics, Inflammation & Post-op Cognitive Dysfunction awarded by National Institutes of Health 1999 - 2006
- Aging And Cognition After Cardiac Surgery awarded by National Institutes of Health 1999 - 2004
- Genetic Basis of Cognitive Decline After Surgery awarded by National Institutes of Health 1997 - 2002
- Genetic Basis Of Cognitive Decline After Surgery awarded by National Institutes of Health 1997 - 1999
- Aging, Cognition And Quality Of Life After Cardiac Surgery awarded by National Institutes of Health 1996 - 1999
- Genetic Basis Of Cognitive Decline After Surgery awarded by National Institutes of Health 1997 - 1999
- Aging And Cognitive After Cardiac Surgery awarded by National Institutes of Health 1996 - 1999
- Aging And Cognition After Cardiac Surgery awarded by National Institutes of Health 1994 - 1999
- Aging And Cognition After Cardiac Surgery awarded by National Institutes of Health 1991 - 1999
Publications & Artistic Works
Selected Publications
- Books
  - Grocott, HP, Newman, MF, and Harmel, MH. Foreword to the first edition. January 1, 2012. Full Text
- Academic Articles
  - Smith, PJ, Browndyke, JN, Monge, ZA, Harshbarger, TB, James, ML, Gaca, JG, Alexander, JH, Berger, MM, Newman, MF, Milano, CA, Mathew, JP, and Neurologic Outcomes Research Group (NORG), . "Longitudinal Changes in Regional Cerebral Perfusion and Cognition After Cardiac Operation." The Annals of Thoracic Surgery 107, no. 1 (January 2019): 112-118. Full Text Open Access Copy
  - Waldron, NH, Cooter, M, Piccini, JP, Anstrom, KJ, Klinger, RY, Kertai, MD, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Predictive ability of perioperative atrial fibrillation risk indices in cardiac surgery patients: a retrospective cohort study." Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie 65, no. 7 (July 2018): 786-796. Full Text
  - Wang, A, Wu, A, Wojdyla, D, Lopes, RD, Newby, LK, Newman, MF, Smith, PK, and Alexander, JH. "Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery." American Heart Journal 199 (May 2018): 150-155. Full Text
  - Browndyke, JN, Berger, M, Smith, PJ, Harshbarger, TB, Monge, ZA, Panchal, V, Bisanar, TL, Glower, DD, Alexander, JH, Cabeza, R, Welsh-Bohmer, K, Newman, MF, Mathew, JP, and Duke Neurologic Outcomes Research Group (NORG), . "Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults." Human Brain Mapping 39, no. 2 (February 2018): 985-1003. Full Text Open Access Copy
  - Berger, M, Ponnusamy, V, Greene, N, Cooter, M, Nadler, JW, Friedman, A, McDonagh, DL, Laskowitz, DT, Newman, MF, Shaw, LM, Warner, DS, Mathew, JP, James, ML, and MAD-PIA Investigators, . "The Effect of Propofol vs. Isoflurane Anesthesia on Postoperative Changes in Cerebrospinal Fluid Cytokine Levels: Results from a Randomized Trial." Frontiers in Immunology 8 (January 2017): 1528-null. Full Text
  - Browndyke, JN, Berger, M, Harshbarger, TB, Smith, PJ, White, W, Bisanar, TL, Alexander, JH, Gaca, JG, Welsh-Bohmer, K, Newman, MF, and Mathew, JP. "Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings." Journal of the American Geriatrics Society 65, no. 1 (January 2017): e6-e12. Full Text Open Access Copy
  - Giattino, CM, Gardner, JE, Sbahi, FM, Roberts, KC, Cooter, M, Moretti, E, Browndyke, JN, Mathew, JP, Woldorff, MG, Berger, M, and MADCO-PC Investigators, . "Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults." Frontiers in Systems Neuroscience 11 (January 2017): 24-null. Full Text Open Access Copy
  - Klinger, RY, Cooter, M, Berger, M, Podgoreanu, MV, Stafford-Smith, M, Ortel, TL, Welsby, IJ, Levy, JH, Rinder, HM, Newman, MF, Mathew, JP, and Neurologic Outcomes Research Group (NORG) of The Duke Heart Center, . "Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial." Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie 63, no. 11 (November 2016): 1223-1232. Full Text
  - Berger, M, Nadler, JW, Friedman, A, McDonagh, DL, Bennett, ER, Cooter, M, Qi, W, Laskowitz, DT, Ponnusamy, V, Newman, MF, Shaw, LM, Warner, DS, Mathew, JP, James, ML, and MAD-PIA trial team, . "The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial." Journal of Alzheimer'S Disease : Jad 52, no. 4 (April 2016): 1299-1310. Full Text Open Access Copy
  - Kertai, MD, Qi, W, Li, Y-J, Lombard, FW, Liu, Y, Smith, MP, Stafford-Smith, M, Newman, MF, Milano, CA, Mathew, JP, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers." Journal of Molecular and Cellular Cardiology 92 (March 2016): 109-115. Full Text
  - Reves, JG, and Newman, MF. "Merel Harmel: Portrait of an Anesthesiology Pioneer." Anesthesia and analgesia 122, no. 2 (February 2016): 539-541. Full Text
  - Klinger, RY, Thunberg, CA, White, WD, Fontes, M, Waldron, NH, Piccini, JP, Hughes, GC, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Intraoperative Magnesium Administration Does Not Reduce Postoperative Atrial Fibrillation After Cardiac Surgery." Anesthesia and Analgesia 121, no. 4 (October 2015): 861-867. Full Text
  - Stafford-Smith, M, Li, Y-J, Mathew, JP, Li, Y-W, Ji, Y, Phillips-Bute, BG, Milano, CA, Newman, MF, Kraus, WE, Kertai, MD, Shah, SH, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci." Kidney international 88, no. 4 (October 2015): 823-832. Full Text Open Access Copy
  - Kertai, MD, Li, Y-J, Ji, Y, Qi, W, Lombard, FW, Shah, SH, Kraus, WE, Stafford-Smith, M, Newman, MF, Milano, CA, Waldron, N, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of new-onset atrial fibrillation after coronary artery bypass grafting surgery." American heart journal 170, no. 3 (September 2015): 580-90.e28. Full Text
  - Bartels, K, Li, Y-J, Li, Y-W, White, WD, Laskowitz, DT, Kertai, MD, Stafford-Smith, M, Podgoreanu, MV, Newman, MF, and Mathew, JP. "Apolipoprotein epsilon 4 genotype is associated with less improvement in cognitive function five years after cardiac surgery: a retrospective cohort study." Canadian Journal of Anaesthesia = Journal Canadien D'Anesthesie 62, no. 6 (June 2015): 618-626. Full Text
  - Kertai, MD, Li, Y-J, Li, Y-W, Ji, Y, Alexander, J, Newman, MF, Smith, PK, Joseph, D, Mathew, JP, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery." BMJ open 5, no. 5 (May 6, 2015): e006920-. Full Text Open Access Copy
  - Weisel, RD, Nussmeier, N, Newman, MF, Pearl, RG, Wechsler, AS, Ambrosio, G, Pitt, B, Clare, RM, Pieper, KS, Mongero, L, Reece, TL, Yau, TM, Fremes, S, Menasché, P, Lira, A, Harrington, RA, Ferguson, TB, and RED-CABG Executive and Steering Committees, . "Predictors of contemporary coronary artery bypass grafting outcomes." The Journal of thoracic and cardiovascular surgery 148, no. 6 (December 2014): 2720-6.e1-2-. Full Text
  - Weisel, RD, Nussmeier, N, Newman, MF, Pearl, RG, Wechsler, AS, Ambrosio, G, Pitt, B, Clare, RM, Pieper, KS, Mongero, L, Reece, TL, Yau, TM, Fremes, S, Menasché, P, Lira, A, Harrington, RA, and Ferguson, TB. "Predictors of contemporary coronary artery bypass grafting outcomes." Journal of Thoracic and Cardiovascular Surgery 148, no. 6 (December 1, 2014): 2720-2726.e2. Full Text
  - Welsby, IJ, Phillips-Bute, B, Mathew, JP, Newman, MF, Becker, R, Rao, S, Milano, CA, and Stafford-Smith, M. "ABO blood group influences transfusion and survival after cardiac surgery." Journal of thrombosis and thrombolysis 38, no. 3 (October 2014): 402-408. Full Text
  - Fontes, MT, McDonagh, DL, Phillips-Bute, B, Welsby, IJ, Podgoreanu, MV, Fontes, ML, Stafford-Smith, M, Newman, MF, Mathew, JP, and Neurologic Outcome Research Group (NORG) of the Duke Heart Center, . "Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction." J Cardiothorac Vasc Anesth 28, no. 3 (June 2014): 462-466. Full Text Link to Item
  - McDonagh, DL, Berger, M, Mathew, JP, Graffagnino, C, Milano, CA, and Newman, MF. "Neurological complications of cardiac surgery." The Lancet. Neurology 13, no. 5 (May 2014): 490-502. (Review) Full Text
  - Kertai, MD, Esper, SA, Akushevich, I, Voora, D, Ginsburg, GS, Stafford-Smith, M, Grichnik, K, Newman, MF, Fontes, ML, Smith, P, Podgoreanu, MV, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery." The Journal of thoracic and cardiovascular surgery 147, no. 4 (April 2014): 1368-1375.e3. Full Text Open Access Copy
  - Mathew, JP, Laskowitz, DT, and Newman, MF. "Response to letter regarding article, "Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery"." Stroke 45, no. 3 (March 2014): e45-. (Letter) Full Text
  - "Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery." Journal of Thoracic and Cardiovascular Surgery 147, no. 4 (January 1, 2014). Full Text
  - Fontes, MT, McDonagh, DL, Phillips-Bute, B, Welsby, IJ, Podgoreanu, MV, Fontes, ML, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction." Journal of Cardiothoracic and Vascular Anesthesia 28, no. 3 (January 1, 2014): 462-466. Full Text
  - Mathew, JP, Laskowitz, DT, and Newman, MF. "Response to letter regarding article, "Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery"." Stroke; a Journal of Cerebral Circulation 45, no. 3 (January 1, 2014). Full Text
  - McDonagh, DL, Berger, M, Mathew, JP, Graffagnino, C, Milano, CA, and Newman, MF. "Neurological complications of cardiac surgery." The Lancet Neurology 13, no. 5 (January 1, 2014): 490-502. (Review) Full Text
  - Welsby, IJ, Phillips-Bute, B, Mathew, JP, Newman, MF, Becker, R, Rao, S, Milano, CA, and Stafford-Smith, M. "ABO blood group influences transfusion and survival after cardiac surgery." Journal of Thrombosis and Thrombolysis 38, no. 3 (January 1, 2014): 402-408. Full Text
  - Mathew, JP, White, WD, Schinderle, DB, Podgoreanu, MV, Berger, M, Milano, CA, Laskowitz, DT, Stafford-Smith, M, Blumenthal, JA, Newman, MF, and Neurologic Outcome Research Group (NORG) of The Duke Heart Center, . "Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery." Stroke 44, no. 12 (December 2013): 3407-3413. Full Text
  - Klinger, RY, James, OG, Wong, TZ, Newman, MF, Doraiswamy, PM, and Mathew, JP. "Cortical β-amyloid levels and neurocognitive performance after cardiac surgery. (Published online)" BMJ Open 3, no. 9 (September 20, 2013): e003669-. Full Text Open Access Copy Link to Item
  - Newman, MF, Mathew, JP, and Aronson, S. "The evolution of anesthesiology and perioperative medicine." Anesthesiology 118, no. 5 (May 2013): 1005-1007. Full Text Link to Item
  - Bartels, K, McDonagh, DL, Newman, MF, and Mathew, JP. "Neurocognitive outcomes after cardiac surgery." Current Opinion in Anaesthesiology 26, no. 1 (February 2013): 91-97. (Review) Full Text
  - Fontes, MT, Swift, RC, Phillips-Bute, B, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, Mathew, JP, and Neurologic Outcome Research Group of the Duke Heart Center, . "Predictors of cognitive recovery after cardiac surgery." Anesthesia and Analgesia 116, no. 2 (February 2013): 435-442. Full Text
  - Aronson, S, Phillips-Bute, B, Stafford-Smith, M, Fontes, M, Gaca, J, Mathew, JP, and Newman, MF. "The association of postcardiac surgery acute kidney injury with intraoperative systolic blood pressure hypotension." Anesthesiol Res Pract 2013 (2013): 174091-. Full Text Open Access Copy Link to Item
  - Fontes, MT, Swift, RC, Phillips-Bute, B, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Predictors of cognitive recovery after cardiac surgery." Anesthesia and Analgesia 116, no. 2 (2013): 435-442. Full Text
  - Newman, MF, Ferguson, TB, White, JA, Ambrosio, G, Koglin, J, Nussmeier, NA, Pearl, RG, Pitt, B, Wechsler, AS, Weisel, RD, Reece, TL, Lira, A, Harrington, RA, and RED-CABG Steering Committee and Investigators, . "Effect of adenosine-regulating agent acadesine on morbidity and mortality associated with coronary artery bypass grafting: the RED-CABG randomized controlled trial." JAMA 308, no. 2 (July 11, 2012): 157-164. Full Text Link to Item
  - Lobato, RL, White, WD, Mathew, JP, Newman, MF, Smith, PK, McCants, CB, Alexander, JH, Podgoreanu, MV, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "Thrombomodulin gene variants are associated with increased mortality after coronary artery bypass surgery in replicated analyses." Circulation 124, no. 11 Suppl (September 2011): S143-S148. Full Text
  - Swaminathan, M, Nicoara, A, Phillips-Bute, BG, Aeschlimann, N, Milano, CA, Mackensen, GB, Podgoreanu, MV, Velazquez, EJ, Stafford-Smith, M, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery." Ann Thorac Surg 91, no. 6 (June 2011): 1844-1850. Full Text Link to Item
  - Aronson, S, Dyke, CM, Levy, JH, Cheung, AT, Lumb, PD, Avery, EG, Hu, M-Y, and Newman, MF. "Does perioperative systolic blood pressure variability predict mortality after cardiac surgery? An exploratory analysis of the ECLIPSE trials." Anesthesia and Analgesia 113, no. 1 (2011): 19-30. Full Text
  - Hsu, Y-W, Somma, J, Newman, MF, and Mathew, JP. "Population pharmacokinetics of lidocaine administered during and after cardiac surgery." Journal of Cardiothoracic and Vascular Anesthesia 25, no. 6 (2011): 931-936. Full Text
  - Lobato, RL, White, WD, Mathew, JP, Newman, MF, Alexander, JH, and Podgoreanu, MV. "Thrombomodulin Variants are Associated with Increased Mortality following CABG Surgery in Replicated Analyses." CIRCULATION 122, no. 21 (November 23, 2010). Link to Item
  - McDonagh, DL, Mathew, JP, White, WD, and Newman, MF. "In reply." Anesthesiology 113, no. 5 (November 1, 2010): 1248-1250. (Letter) Full Text
  - Welsby, IJ, Lockhart, E, Phillips-Bute, B, Campbell, ML, Mathew, JP, Newman, MF, Peterson, E, Milano, CA, Mark Stafford-Smith for members of the Cardiothoracic Anesthesiology Research Endeavors (C.A.R.E.), Department of Anesthesiology, and Duke University Medical Center, . "Storage age of transfused platelets and outcomes after cardiac surgery." Transfusion 50, no. 11 (November 2010): 2311-2317. Full Text
  - Taekman, JM, Stafford-Smith, M, Velazquez, EJ, Wright, MC, Phillips-Bute, BG, Pfeffer, MA, Sellers, MA, Pieper, KS, Newman, MF, Van de Werf, F, Diaz, R, Leimberger, J, and Califf, RM. "Departures from the protocol during conduct of a clinical trial: a pattern from the data record consistent with a learning curve." Qual Saf Health Care 19, no. 5 (October 2010): 405-410. Full Text Link to Item
  - Aronson, S, Stafford-Smith, M, Phillips-Bute, B, Shaw, A, Gaca, J, Newman, M, and Cardiothoracic Anesthesiology Research Endeavors, . "Intraoperative systolic blood pressure variability predicts 30-day mortality in aortocoronary bypass surgery patients." Anesthesiology 113, no. 2 (August 2010): 305-312. Full Text
  - Welsby, IJ, Podgoreanu, MV, Phillips-Bute, B, Morris, R, Mathew, JP, Smith, PK, Newman, MF, Schwinn, DA, Stafford-Smith, M, and Perioperative Genetics and Safety Outcomes Study Investigative Team, . "Association of the 98T ELAM-1 polymorphism with increased bleeding after cardiac surgery." J Cardiothorac Vasc Anesth 24, no. 3 (June 2010): 427-433. Full Text Link to Item
  - Swaminathan, M, Hudson, CCC, Phillips-Bute, BG, Patel, UD, Mathew, JP, Newman, MF, Milano, CA, Shaw, AD, and Stafford-Smith, M. "Impact of early renal recovery on survival after cardiac surgery-associated acute kidney injury." Ann Thorac Surg 89, no. 4 (April 2010): 1098-1104. Full Text Link to Item
  - Nikolov, NM, Fontes, ML, White, WD, Aronson, S, Bar-Yosef, S, Gaca, JG, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Pulse pressure and long-term survival after coronary artery bypass graft surgery." Anesthesia and Analgesia 110, no. 2 (February 2010): 335-340. Full Text
  - Bennett-Guerrero, E, Stafford-Smith, M, Waweru, PM, Bredehoeft, SJ, Campbell, ML, Haley, NR, Phillips-Bute, B, Newman, MF, and Bandarenko, N. "A prospective, double-blind, randomized clinical feasibility trial of controlling the storage age of red blood cells for transfusion in cardiac surgical patients." Transfusion 49, no. 7 (July 2009): 1375-1383. Full Text Link to Item
  - Mathew, JP, Mackensen, GB, Phillips-Bute, B, Grocott, HP, Glower, DD, Laskowitz, DT, Blumenthal, JA, Newman, MF, and Neurologic Outcome Research Group (NORG) of the Duke Heart Center, . "Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery." Stroke 40, no. 3 (March 2009): 880-887. Full Text
  - Phillips-Bute, B, Mathew, JP, Blumenthal, JA, Morris, RW, Podgoreanu, MV, Smith, M, Stafford-Smith, M, Grocott, HP, Schwinn, DA, Newman, MF, and Perioperative Genetics and Safety Outcomes Investigative Team, . "Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery." Psychosomatic Medicine 70, no. 9 (November 2008): 953-959. Full Text
  - Aronson, S, Dyke, CM, Stierer, KA, Levy, JH, Cheung, AT, Lumb, PD, Kereiakes, DJ, and Newman, MF. "The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients." Anesthesia and Analgesia 107, no. 4 (October 2008): 1110-1121. Full Text
  - Singla, N, Warltier, DC, Gandhi, SD, Lumb, PD, Sladen, RN, Aronson, S, Newman, MF, Corwin, HL, and ESCAPE-2 Study Group, . "Treatment of acute postoperative hypertension in cardiac surgery patients: an efficacy study of clevidipine assessing its postoperative antihypertensive effect in cardiac surgery-2 (ESCAPE-2), a randomized, double-blind, placebo-controlled trial." Anesthesia and Analgesia 107, no. 1 (July 2008): 59-67. Full Text
  - Shaw, AD, Stafford-Smith, M, White, WD, Phillips-Bute, B, Swaminathan, M, Milano, C, Welsby, IJ, Aronson, S, Mathew, JP, Peterson, ED, and Newman, MF. "The effect of aprotinin on outcome after coronary-artery bypass grafting." The New England Journal of Medicine 358, no. 8 (February 2008): 784-793. Full Text
  - Newman, MF. "Anaesthesia and the brain." Southern African Journal of Anaesthesia and Analgesia 14, no. 1 (January 1, 2008): 90-null. Full Text
  - Puskas, F, Grocott, HP, White, WD, Mathew, JP, Newman, MF, and Bar-Yosef, S. "Intraoperative hyperglycemia and cognitive decline after CABG." Ann Thorac Surg 84, no. 5 (November 2007): 1467-1473. Full Text Link to Item
  - Swaminathan, M, Morris, RW, De Meyts, DD, Podgoreanu, MV, Jollis, JG, Grocott, HP, Milano, CA, Newman, MF, and Mathew, JP. "Deterioration of regional wall motion immediately after coronary artery bypass graft surgery is associated with long-term major adverse cardiac events." Anesthesiology 107, no. 5 (November 2007): 739-745. Full Text Link to Item
  - Levy, JH, Mancao, MY, Gitter, R, Kereiakes, DJ, Grigore, AM, Aronson, S, and Newman, MF. "Clevidipine effectively and rapidly controls blood pressure preoperatively in cardiac surgery patients: the results of the randomized, placebo-controlled efficacy study of clevidipine assessing its preoperative antihypertensive effect in cardiac surgery-1." Anesthesia and Analgesia 105, no. 4 (October 2007): 918-925. Full Text
  - Mathew, JP, Mackensen, GB, Phillips-Bute, B, Stafford-Smith, M, Podgoreanu, MV, Grocott, HP, Hill, SE, Smith, PK, Blumenthal, JA, Reves, JG, Newman, MF, and Neurologic Outcome Research Group (NORG) of the Duke Heart Center, . "Effects of extreme hemodilution during cardiac surgery on cognitive function in the elderly." Anesthesiology 107, no. 4 (October 2007): 577-584. Full Text
  - Mathew, JP, Podgoreanu, MV, Grocott, HP, White, WD, Morris, RW, Stafford-Smith, M, Mackensen, GB, Rinder, CS, Blumenthal, JA, Schwinn, DA, Newman, MF, and PEGASUS Investigative Team, . "Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery." Journal of the American College of Cardiology 49, no. 19 (May 2007): 1934-1942. Full Text
  - Mitchell, JD, Grocott, HP, Phillips-Bute, B, Mathew, JP, Newman, MF, and Bar-Yosef, S. "Cytokine secretion after cardiac surgery and its relationship to postoperative fever." Cytokine 38, no. 1 (April 2007): 37-42. Full Text Link to Item
  - Bennett Guerrero, E, Grocott, HP, Levy, JH, Stierer, KA, Hogue, CW, Cheung, AT, Newman, MF, Carter, AA, Rossignol, DP, and Collard, CD. "A phase II, double-blind, placebo-controlled, ascending-dose study of Eritoran (E5564), a lipid A antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass." Anesthesia and analgesia 104, no. 2 (February 2007): 378-383. (Academic Article)
  - Newman, MF. "Open heart surgery and cognitive decline." Cleve Clin J Med 74 Suppl 1 (February 2007): S52-S55. (Review) Link to Item
  - Doraiswamy, PM, Babyak, MA, Hennig, T, Trivedi, R, White, WD, Mathew, JP, Newman, MF, and Blumenthal, JA. "Donepezil for cognitive decline following coronary artery bypass surgery: a pilot randomized controlled trial." Psychopharmacology Bulletin 40, no. 2 (January 2007): 54-62.
  - Haverich, A, Shernan, SK, Levy, JH, Chen, JC, Carrier, M, Taylor, KM, Van de Werf, F, Newman, MF, Adams, PX, Todaro, TG, van der Laan, M, and Verrier, ED. "Pexelizumab reduces death and myocardial infarction in higher risk cardiac surgical patients." The Annals of Thoracic Surgery 82, no. 2 (August 2006): 486-492. Full Text
  - Newman, MF, Mathew, JP, Grocott, HP, Mackensen, GB, Monk, T, Welsh-Bohmer, KA, Blumenthal, JA, Laskowitz, DT, and Mark, DB. "Central nervous system injury associated with cardiac surgery." Lancet (London, England) 368, no. 9536 (August 2006): 694-703. (Review) Full Text
  - Moretti, EW, Newman, MF, Muhlbaier, LH, Whellan, D, Petersen, RP, Rossignol, D, McCants, CB, Phillips-Bute, B, and Bennett-Guerrero, E. "Effects of decreased preoperative endotoxin core antibody levels on long-term mortality after coronary artery bypass graft surgery." Arch Surg 141, no. 7 (July 2006): 637-641. Full Text Link to Item
  - Podgoreanu, MV, White, WD, Morris, RW, Mathew, JP, Stafford-Smith, M, Welsby, IJ, Grocott, HP, Milano, CA, Newman, MF, Schwinn, DA, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery." Circulation 114, no. 1 Suppl (July 2006): I275-I281. Full Text
  - Hill, SE, Keller, RA, Stafford-Smith, M, Grichnik, K, White, WD, D'Amico, TA, and Newman, MF. "Efficacy of single-dose, multilevel paravertebral nerve blockade for analgesia after thoracoscopic procedures." Anesthesiology 104, no. 5 (May 2006): 1047-1053. Full Text
  - Mathew, JP, Rinder, HM, Smith, BR, Newman, MF, and Rinder, CS. "Transcerebral platelet activation after aortic cross-clamp release is linked to neurocognitive decline." The Annals of Thoracic Surgery 81, no. 5 (May 2006): 1644-1649. Full Text
  - Phillips-Bute, B, Mathew, JP, Blumenthal, JA, Grocott, HP, Laskowitz, DT, Jones, RH, Mark, DB, and Newman, MF. "Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery." Psychosomatic Medicine 68, no. 3 (May 2006): 369-375. Full Text
  - Stafford-Smith, M, and Newman, MF. "What effects do hemodilution and blood transfusion during cardiopulmonary bypass have on renal outcomes?." Nat Clin Pract Nephrol 2, no. 4 (April 2006): 188-189. Full Text Link to Item
  - Carrier, M, Ménasché, P, Levy, JH, Newman, MF, Taylor, KM, Haverich, A, Chen, JC, Shernan, SK, Van de Werf, F, van der Laan, M, Todaro, TG, Adams, PX, and Verrier, ED. "Inhibition of complement activation by pexelizumab reduces death in patients undergoing combined aortic valve replacement and coronary artery bypass surgery." The Journal of thoracic and cardiovascular surgery 131, no. 2 (February 2006): 352-356. (Academic Article)
  - Wright, MC, Taekman, JM, Barber, L, Hobbs, G, Newman, MF, and Stafford-Smith, M. "The use of high-fidelity human patient simulation as an evaluative tool in the development of clinical research protocols and procedures." Contemporary Clinical Trials 26, no. 6 (December 2005): 646-659. Full Text
  - Moretti, EW, Morris, RW, Podgoreanu, M, Schwinn, DA, Newman, MF, Bennett, E, Moulin, VG, Mba, UU, Laskowitz, DT, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "APOE polymorphism is associated with risk of severe sepsis in surgical patients." Crit Care Med 33, no. 11 (November 2005): 2521-2526. Link to Item
  - Fleisher, LA, Newman, MF, St Aubin, LB, Cropp, AB, Billing, CB, Bonney, S, Mackey, WC, Poldermans, D, Corbalan, R, Pereira, AH, Coriat, P, and Perioperative Myocardial Ischemic Injury Investigators, . "Efficacy of zoniporide, an Na/H exchange ion inhibitor, for reducing perioperative cardiovascular events in vascular surgery patients." J Cardiothorac Vasc Anesth 19, no. 5 (October 2005): 570-576. Full Text Link to Item
  - Hill, SE, Grocott, HP, Leone, BJ, White, WD, Newman, MF, and Neurologic Outcome Research Group of the Duke Heart Center, . "Cerebral physiology of cardiac surgical patients treated with the perfluorocarbon emulsion, AF0144." Ann Thorac Surg 80, no. 4 (October 2005): 1401-1407. Full Text Link to Item
  - Grocott, HP, White, WD, Morris, RW, Podgoreanu, MV, Mathew, JP, Nielsen, DM, Schwinn, DA, Newman, MF, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Genetic polymorphisms and the risk of stroke after cardiac surgery." Stroke 36, no. 9 (September 2005): 1854-1858. Full Text Link to Item
  - Clark, JA, Bar-Yosef, S, Anderson, A, Newman, MF, Landolfo, K, and Grocott, HP. "Postoperative hyperthermia following off-pump versus on-pump coronary artery bypass surgery." J Cardiothorac Vasc Anesth 19, no. 4 (August 2005): 426-429. Full Text Link to Item
  - Stafford-Smith, M, Lefrak, EA, Qazi, AG, Welsby, IJ, Barber, L, Hoeft, A, Dorenbaum, A, Mathias, J, Rochon, JJ, Newman, MF, and Members of the Global Perioperative Research Organization, . "Efficacy and safety of heparinase I versus protamine in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass." Anesthesiology 103, no. 2 (August 2005): 229-240. Full Text
  - Corkey, WB, Phillips-Bute, B, Baudet, B, Mathew, JP, Newman, MF, and Grocott, HP. "Brief report: The declining incidence of cerebral hyperthermia during cardiac surgery: a seven-year experience in 6,334 patients." Can J Anaesth 52, no. 6 (June 2005): 626-629. Link to Item
  - Mathew, JP, Grocott, HP, McCurdy, JR, Ti, LK, Davis, RD, Laskowitz, DT, Podgoreanu, MV, Swaminathan, M, Lynch, J, Stafford-Smith, M, White, WD, and Newman, MF. "Preoperative statin therapy does not reduce cognitive dysfunction after cardiopulmonary bypass." Journal of Cardiothoracic and Vascular Anesthesia 19, no. 3 (June 2005): 294-299. Full Text
  - Newman, MF. "Foreward." Middle East Journal of Anesthesiology 18, no. 2 (June 1, 2005).
  - Welsby, IJ, Podgoreanu, MV, Phillips-Bute, B, Mathew, JP, Smith, PK, Newman, MF, Schwinn, DA, Stafford-Smith, M, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Genetic factors contribute to bleeding after cardiac surgery." J Thromb Haemost 3, no. 6 (June 2005): 1206-1212. Full Text Link to Item
  - Lei, B, Morris, DP, Smith, MP, Svetkey, LP, Newman, MF, Rotter, JI, Buchanan, TA, Beckstrom-Sternberg, SM, Green, ED, and Schwinn, DA. "Novel human alpha1a-adrenoceptor single nucleotide polymorphisms alter receptor pharmacology and biological function." Naunyn Schmiedeberg'S Archives of Pharmacology 371, no. 3 (March 10, 2005): 229-239. Full Text
  - Stafford-Smith, M, Podgoreanu, M, Swaminathan, M, Phillips-Bute, B, Mathew, JP, Hauser, EH, Winn, MP, Milano, C, Nielsen, DM, Smith, M, Morris, R, Newman, MF, Schwinn, DA, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery." Am J Kidney Dis 45, no. 3 (March 2005): 519-530. Full Text Link to Item
  - Welsby, IJ, Newman, MF, Phillips-Bute, B, Messier, RH, Kakkis, ED, and Stafford-Smith, M. "Hemodynamic changes after protamine administration: association with mortality after coronary artery bypass surgery." Anesthesiology 102, no. 2 (February 2005): 308-314. Full Text
  - Conlon, PJ, Crowley, J, Stack, R, Neary, JJ, Stafford-Smith, M, White, WD, Newman, MF, and Landolfo, K. "Renal artery stenosis is not associated with the development of acute renal failure following coronary artery bypass grafting." Ren Fail 27, no. 1 (2005): 81-86. Link to Item
  - Newman, MF, Blumenthal, JA, and Mark, DB. "Fixing the heart: must the brain pay the price?." Circulation 110, no. 22 (November 30, 2004): 3402-3403. Full Text Link to Item
  - Mathew, JP, Shernan, SK, White, WD, Fitch, JCK, Chen, JC, Bell, L, and Newman, MF. "Preliminary report of the effects of complement suppression with pexelizumab on neurocognitive decline after coronary artery bypass graft surgery." Stroke 35, no. 10 (October 2004): 2335-2339. Full Text Link to Item
  - Sreeram, GM, Grocott, HP, White, WD, Newman, MF, and Stafford-Smith, M. "Transcranial Doppler emboli count predicts rise in creatinine after coronary artery bypass graft surgery." J Cardiothorac Vasc Anesth 18, no. 5 (October 2004): 548-551. Link to Item
  - Bar-Yosef, S, Mathew, JP, Newman, MF, Landolfo, KP, Grocott, HP, Neurological Outcome Research Group, , and C A R E Investigators of the Duke Heart Center, . "Prevention of cerebral hyperthermia during cardiac surgery by limiting on-bypass rewarming in combination with post-bypass body surface warming: a feasibility study." Anesth Analg 99, no. 3 (September 2004): 641-646. Full Text Link to Item
  - MacKensen, GB, Swaminathan, M, Ti, LK, Grocott, HP, Phillips-Bute, BG, Mathew, JP, Newman, MF, Milano, CA, Stafford-Smith, M, Perioperative Outcomes Research Group, , and Cardiothoracic Anesthesiology Research Endeavors (C.A.R.E.) Investigators of the Duke Heart Center, . "Preliminary report on the interaction of apolipoprotein E polymorphism with aortic atherosclerosis and acute nephropathy after CABG." Ann Thorac Surg 78, no. 2 (August 2004): 520-526. Full Text Link to Item
  - McKinlay, KH, Schinderle, DB, Swaminathan, M, Podgoreanu, MV, Milano, CA, Messier, RH, El-Moalem, H, Newman, MF, Clements, FM, and Mathew, JP. "Predictors of inotrope use during separation from cardiopulmonary bypass." J Cardiothorac Vasc Anesth 18, no. 4 (August 2004): 404-408. Link to Item
  - Taekman, JM, Hobbs, G, Barber, L, Phillips-Bute, BG, Wright, MC, Newman, MF, and Stafford-Smith, M. "Preliminary report on the use of high-fidelity simulation in the training of study coordinators conducting a clinical research protocol." Anesth Analg 99, no. 2 (August 2004): 521-527. Full Text Link to Item
  - Booth, JV, Ward, EE, Colgan, KC, Funk, BL, El-Moalem, H, Smith, MP, Milano, C, Smith, PK, Newman, MF, Schwinn, DA, and Duke Heart Center Perioperative Desensitization Group, . "Metoprolol and coronary artery bypass grafting surgery: does intraoperative metoprolol attenuate acute beta-adrenergic receptor desensitization during cardiac surgery?." Anesthesia and Analgesia 98, no. 5 (May 2004): 1224-1231. Full Text
  - Lett, HS, Blumenthal, JA, Babyak, MA, Sherwood, A, Strauman, T, Robins, C, and Newman, MF. "Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment." Psychosomatic Medicine 66, no. 3 (May 2004): 305-315. (Review) Full Text
  - Verrier, ED, Shernan, SK, Taylor, KM, Werf, FVD, Newman, MF, Chen, JC, Carrier, M, Haverich, A, Malloy, KJ, Adams, PX, Todaro, TG, Mojcik, CF, Rollins, SA, Levy, JH, and Investigators, PRIMO-CABG. "Terminal complement blockade with pexelizumab during coronary artery bypass graft surgery requiring cardiopulmonary bypass: a randomized trial." JAMA : the journal of the American Medical Association 291, no. 19 (May 2004): 2319-2327. (Academic Article)
  - Djaiani, G, Phillips-Bute, B, Podgoreanu, M, Messier, RH, Mathew, JP, Clements, F, and Newman, MF. "The association of patent foramen ovale and atrial fibrillation after coronary artery bypass graft surgery." Anesth Analg 98, no. 3 (March 2004): 585-589. Link to Item
  - Galli, KK, Zimmerman, RA, Jarvik, GP, Wernovsky, G, Kuypers, MK, Clancy, RR, Montenegro, LM, Mahle, WT, Newman, MF, Saunders, AM, Nicolson, SC, Spray, TL, and Gaynor, JW. "Periventricular leukomalacia is common after neonatal cardiac surgery." The Journal of Thoracic and Cardiovascular Surgery 127, no. 3 (March 2004): 692-704. Full Text
  - Kong, DF, Eisenstein, EL, Sketch, MH, Zidar, JP, Ryan, TJ, Harrington, RA, Newman, MF, Smith, PK, Mark, DB, and Califf, RM. "Economic impact of drug-eluting stents on hospital systems: a disease-state model." American Heart Journal 147, no. 3 (March 2004): 449-456. Full Text
  - Grocott, HP, Mathew, JP, Carver, EH, Phillips-Bute, B, Landolfo, KP, Newman, MF, and Duke Heart Center Neurologic Outcome Research Group, . "A randomized controlled trial of the Arctic Sun Temperature Management System versus conventional methods for preventing hypothermia during off-pump cardiac surgery." Anesthesia and Analgesia 98, no. 2 (February 2004): 298-302. Full Text
  - Lynch, JR, Blessing, R, White, WD, Grocott, HP, Newman, MF, and Laskowitz, DT. "Novel diagnostic test for acute stroke." Stroke 35, no. 1 (January 2004): 57-63. Full Text Link to Item
  - Gaynor, JW, Gerdes, M, Zackai, EH, Bernbaum, J, Wernovsky, G, Clancy, RR, Newman, MF, Saunders, AM, Heagerty, PJ, D'Agostino, JA, McDonald-McGinn, D, Nicolson, SC, Spray, TL, and Jarvik, GP. "Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery." The Journal of Thoracic and Cardiovascular Surgery 126, no. 6 (December 2003): 1736-1745. Full Text
  - Kilts, JD, Akazawa, T, El-Moalem, HE, Mathew, JP, Newman, MF, and Kwatra, MM. "Age increases expression and receptor-mediated activation of G alpha i in human atria." Journal of Cardiovascular Pharmacology 42, no. 5 (November 2003): 662-670. Full Text
  - Phillips Bute, B, Mathew, J, Blumenthal, JA, Welsh-Bohmer, K, White, WD, Mark, D, Landolfo, K, and Newman, MF. "Female gender is associated with impaired quality of life 1 year after coronary artery bypass surgery." Psychosom Med 65, no. 6 (November 2003): 944-951. Link to Item
  - Scarborough, JE, White, W, Derilus, FE, Mathew, JP, Newman, MF, Landolfo, KP, and Neurological Outcome Research Group, . "Combined use of off-pump techniques and a sutureless proximal aortic anastomotic device reduces cerebral microemboli generation during coronary artery bypass grafting." The Journal of Thoracic and Cardiovascular Surgery 126, no. 5 (November 2003): 1561-1567. Full Text
  - Swaminathan, M, Phillips-Bute, BG, Conlon, PJ, Smith, PK, Newman, MF, and Stafford-Smith, M. "The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery." Ann Thorac Surg 76, no. 3 (September 2003): 784-791. Link to Item
  - Blumenthal, JA, Lett, HS, Babyak, MA, White, W, Smith, PK, Mark, DB, Jones, R, Mathew, JP, Newman, MF, and NORG Investigators, . "Depression as a risk factor for mortality after coronary artery bypass surgery." Lancet 362, no. 9384 (August 23, 2003): 604-609. Full Text Link to Item
  - Booth, JV, Phillips-Bute, B, McCants, CB, Podgoreanu, MV, Smith, PK, Mathew, JP, and Newman, MF. "Low serum magnesium level predicts major adverse cardiac events after coronary artery bypass graft surgery." Am Heart J 145, no. 6 (June 2003): 1108-1113. Full Text Link to Item
  - Djaiani, GN, Phillips-Bute, B, Blumenthal, JA, Newman, MF, Neurologic Outcome Research Group, , and CARE Investigators of the Duke Heart Center, . "Chronic exposure to nicotine does not prevent neurocognitive decline after cardiac surgery." J Cardiothorac Vasc Anesth 17, no. 3 (June 2003): 341-345. Link to Item
  - Stanley, TO, Grocott, HP, Phillips-Bute, B, Mathew, JP, Landolfo, KP, Newman, MF, Neurologic Outcome Research Group C.A.R.E, , and Investigators of the Duke Heart Center, . "Preliminary evaluation of the Arctic Sun temperature-controlling system during off-pump coronary artery bypass surgery." Ann Thorac Surg 75, no. 4 (April 2003): 1140-1144. Link to Item
  - Albahrani, MJ, Swaminathan, M, Phillips-Bute, B, Smith, PK, Newman, MF, Mathew, JP, and Stafford-Smith, M. "Postcardiac surgery complications: association of acute renal dysfunction and atrial fibrillation." Anesthesia and Analgesia 96, no. 3 (March 2003): 637-643. Full Text
  - Hagen, SA, Kondyra, AL, Grocott, HP, El-Moalem, H, Bainbridge, D, Mathew, JP, Newman, MF, Reves, JG, Schwinn, DA, and Kwatra, MM. "Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells." Anesthesiology 98, no. 2 (February 2003): 343-348. Full Text
  - Mathew, JP, Grocott, HP, Phillips-Bute, B, Stafford-Smith, M, Laskowitz, DT, Rossignol, D, Blumenthal, JA, Newman, MF, Neurologic Outcome Research Group of the Duke Heart Center, , and Cardiothoracic Anesthesiology Research Endeavors Investigators of the Duke Heart Center, . "Lower endotoxin immunity predicts increased cognitive dysfunction in elderly patients after cardiac surgery." Stroke 34, no. 2 (February 2003): 508-513. Full Text
  - Lucas, S, Shuhaiber, JH, Macleod, J, Smith, GD, Blumenthal, JA, Newman, M, Babyak, MA, Lett, HS, and Mark, D. "Depression as risk factor for mortality after coronary artery bypass surgery [4] (multiple letters)." Lancet 362, no. 9394 (2003): 1499-1502. Full Text
  - Scarborough, JE, White, W, Derilus, FE, Mathew, JP, Newman, MF, and Landolfo, KP. "Neurologic outcomes after coronary artery bypass grafting with and without cardiopulmonary bypass." Semin Thorac Cardiovasc Surg 15, no. 1 (January 2003): 52-62. (Review) Link to Item
  - Ti, LK, Mackensen, GB, Grocott, HP, Laskowitz, DT, Phillips-Bute, BG, Milano, CA, Hilton, AK, Newman, MF, Mathew, JP, and Neurologic Outcome Research Group, . "Apolipoprotein E4 increases aortic atheroma burden in cardiac surgical patients." The Journal of Thoracic and Cardiovascular Surgery 125, no. 1 (January 2003): 211-213. Full Text
  - Hill, SE, Leone, BJ, Faithfull, NS, Flaim, KE, Keipert, PE, and Newman, MF. "Perflubron emulsion (AF0144) augments harvesting of autologous blood: a phase II study in cardiac surgery." J Cardiothorac Vasc Anesth 16, no. 5 (October 2002): 555-560. Link to Item
  - Reynolds, JD, Amory, DW, Grocott, HP, White, WD, and Newman, MF. "Change in plasma glutamate concentration during cardiac surgery is a poor predictor of cognitive outcome." J Cardiothorac Vasc Anesth 16, no. 4 (August 2002): 431-436. Link to Item
  - O'Connor, CM, Velazquez, EJ, Gardner, LH, Smith, PK, Newman, MF, Landolfo, KP, Lee, KL, Califf, RM, and Jones, RH. "Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank)." The American Journal of Cardiology 90, no. 2 (July 2002): 101-107. Full Text
  - Amory, DW, Grigore, A, Amory, JK, Gerhardt, MA, White, WD, Smith, PK, Schwinn, DA, Reves, JG, and Newman, MF. "Neuroprotection is associated with beta-adrenergic receptor antagonists during cardiac surgery: evidence from 2,575 patients." Journal of Cardiothoracic and Vascular Anesthesia 16, no. 3 (June 2002): 270-277. Full Text
  - Sato, Y, Laskowitz, DT, Bennett, ER, Newman, MF, Warner, DS, and Grocott, HP. "Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis?." Anesth Analg 94, no. 6 (June 2002): 1389-1394. Link to Item
  - Welsby, IJ, Bennett-Guerrero, E, Atwell, D, White, WD, Newman, MF, Smith, PK, and Mythen, MG. "The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass." Anesthesia and Analgesia 94, no. 5 (May 2002): 1072-1078. Full Text
  - Mark, DB, and Newman, MF. "Protecting the brain in coronary artery bypass graft surgery." JAMA 287, no. 11 (March 20, 2002): 1448-1450. Link to Item
  - Grocott, HP, Mackensen, GB, Grigore, AM, Mathew, J, Reves, JG, Phillips-Bute, B, Smith, PK, Newman, MF, Neurologic Outcome Research Group (NORG), , and Cardiothoracic Anesthesiology Research Endeavors (CARE) Investigators' of the Duke Heart Center, . "Postoperative hyperthermia is associated with cognitive dysfunction after coronary artery bypass graft surgery." Stroke 33, no. 2 (February 2002): 537-541. Full Text
  - Stanley, TO, Mackensen, GB, Grocott, HP, White, WD, Blumenthal, JA, Laskowitz, DT, Landolfo, KP, Reves, JG, Mathew, JP, Newman, MF, Neurological Outcome Research Group, , and CARE Investigators of the Duke Heart Center, . "The impact of postoperative atrial fibrillation on neurocognitive outcome after coronary artery bypass graft surgery." Anesthesia and Analgesia 94, no. 2 (February 2002): 290-295. Full Text
  - Newman, MF, Kirchner, JL, Phillips-Bute, B, Murkin, J, and Hall, R. "Best evidence in anesthetic practice. Prognosis: Cognitive function at hospital discharge predicts long-term cognitive function after coronary artery bypass surgery." Canadian Journal of Anesthesia 49, no. 5 (2002): 497-499.
  - Sharma, AD, Slaughter, TF, Clements, FM, Sreeram, G, Newman, MF, Phillips-Bute, B, Bredehoeft, SJ, Smith, PK, and Stafford-Smith, M. "Association of leukocyte-depleted blood transfusions with infectious complications after cardiac surgery." Surg Infect (Larchmt) 3, no. 2 (2002): 127-133. Full Text Link to Item
  - Mackensen, GB, Sato, Y, Nellgård, B, Pineda, J, Newman, MF, Warner, DS, and Grocott, HP. "Cardiopulmonary bypass induces neurologic and neurocognitive dysfunction in the rat." Anesthesiology 95, no. 6 (December 2001): 1485-1491. Full Text
  - Newman, MF, Grocott, HP, Mathew, JP, White, WD, Landolfo, K, Reves, JG, Laskowitz, DT, Mark, DB, Blumenthal, JA, and Neurologic Outcome Research Group and the Cardiothoracic Anesthesia Research Endeavors (CARE) Investigators of the Duke Heart Center, . "Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery." Stroke 32, no. 12 (December 2001): 2874-2881. Full Text
  - Grigore, AM, Mathew, J, Grocott, HP, Reves, JG, Blumenthal, JA, White, WD, Smith, PK, Jones, RH, Kirchner, JL, Mark, DB, Newman, MF, Neurological Outcome Research Group, , and CARE Investigators of the Duke Heart Center. Cardiothoracic Anesthesia Research Endeavors, . "Prospective randomized trial of normothermic versus hypothermic cardiopulmonary bypass on cognitive function after coronary artery bypass graft surgery." Anesthesiology 95, no. 5 (November 2001): 1110-1119. Link to Item
  - Swaminathan, M, East, C, Phillips-Bute, B, Newman, MF, Reves, JG, Smith, PK, and Stafford-Smith, M. "Report of a substudy on warm versus cold cardiopulmonary bypass: changes in creatinine clearance." The Annals of Thoracic Surgery 72, no. 5 (November 2001): 1603-1609. Full Text
  - Bainbridge, DT, Mackensen, GB, Newman, MF, Landolfo, KP, and Grocott, HP. "Off-pump coronary artery bypass surgery in a patient with C1 esterase inhibitor deficiency." Anesthesiology 95, no. 3 (September 2001): 795-796. Link to Item
  - Grocott, HP, Newman, MF, El-Moalem, H, Bainbridge, D, Butler, A, and Laskowitz, DT. "Apolipoprotein E genotype differentially influences the proinflammatory and anti-inflammatory response to cardiopulmonary bypass." The Journal of Thoracic and Cardiovascular Surgery 122, no. 3 (September 2001): 622-623. Full Text
  - Ti, LK, Mathew, JP, Mackensen, GB, Grocott, HP, White, WD, Reves, JG, and Newman, MF. "Effect of apolipoprotein E genotype on cerebral autoregulation during cardiopulmonary bypass." Stroke 32, no. 7 (July 2001): 1514-1519. Link to Item
  - Cheng, DC, Newman, MF, Duke, P, Wong, DT, Finegan, B, Howie, M, Fitch, J, Bowdle, TA, Hogue, C, Hillel, Z, Pierce, E, and Bukenya, D. "The efficacy and resource utilization of remifentanil and fentanyl in fast-track coronary artery bypass graft surgery: a prospective randomized, double-blinded controlled, multi-center trial." Anesthesia and Analgesia 92, no. 5 (May 2001): 1094-1102. Full Text
  - Howie, MB, Cheng, D, Newman, MF, Pierce, ET, Hogue, C, Hillel, Z, Bowdle, TA, and Bukenya, D. "A randomized double-blinded multicenter comparison of remifentanil versus fentanyl when combined with isoflurane/propofol for early extubation in coronary artery bypass graft surgery." Anesthesia and Analgesia 92, no. 5 (May 2001): 1084-1093. Full Text
  - Newman, MF, Laskowitz, DT, White, WD, Kirchner, JL, Grocott, HP, Stafford-Smith, M, Sketch, MH, Jones, RH, Reves, JG, and Saunders, AM. "Apolipoprotein E polymorphisms and age at first coronary artery bypass graft." Anesthesia and Analgesia 92, no. 4 (April 2001): 824-829. Full Text
  - Newman, MF. "Troponin I in cardiac surgery: marking the future." Am Heart J 141, no. 3 (March 2001): 325-326. Full Text Link to Item
  - Mathew, JP, Rinder, CS, Howe, JG, Fontes, M, Crouch, J, Newman, MF, Phillips-Bute, B, and Smith, BR. "Platelet PlA2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass. Multicenter Study of Perioperative Ischemia (McSPI) Research Group." Ann Thorac Surg 71, no. 2 (February 2001): 663-666. Link to Item
  - Newman, MF, Kirchner, JL, Phillips-Bute, B, Gaver, V, Grocott, H, Jones, RH, Mark, DB, Reves, JG, Blumenthal, JA, and Neurological Outcome Research Group and the Cardiothoracic Anesthesiology Research Endeavors Investigators, . "Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery." The New England Journal of Medicine 344, no. 6 (February 2001): 395-402. Full Text
  - Grocott, HP, Mackensen, GB, Newman, MF, and Warner, DS. "Neurological injury during cardiopulmonary bypass in the rat." Perfusion 16, no. 1 (January 2001): 75-81. Full Text Link to Item
  - Khatri, P, Babyak, M, Croughwell, ND, Davis, R, White, WD, Newman, MF, Reves, JG, Mark, DB, and Blumenthal, JA. "Temperature during coronary artery bypass surgery affects quality of life." Ann Thorac Surg 71, no. 1 (January 2001): 110-116. Link to Item
  - Mack, MJ, Magee, MJ, Dewey, TM, Aklog, L, Wilner, AP, Malphurs, JE, Roscoe, LA, Taggart, DP, Browne, SM, Halligan, PW, Newman, MF, and Blumenthal, JA. "Neurocognitive function after coronary-artery bypass surgery [1]." New England Journal of Medicine 345, no. 7 (2001): 543-545. Full Text
  - Mathew, JP, Rinder, CS, Howe, JG, Fontes, M, Crouch, J, Newman, MF, Phillips-Bute, B, and Smith, BR. "Platelet p1^A2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass." Annals of Thoracic Surgery 71, no. 2 (January 1, 2001): 663-666. Full Text
  - Newman, MF, Booth, JV, Laskowitz, DT, Schwinn, DA, Grocott, HP, and Mathew, JP. "Genetic predictors of perioperative neurological and cognitive injury and recovery." Best Practice and Research: Clinical Anaesthesiology 15, no. 2 (January 1, 2001): 247-276. Full Text
  - Grigore, AM, Grocott, HP, and Newman, MF. "Anesthetic management of a patient with a brain tumor for cardiac surgery." J Cardiothorac Vasc Anesth 14, no. 6 (December 2000): 702-704. Full Text Link to Item
  - Gamoso, MG, Phillips-Bute, B, Landolfo, KP, Newman, MF, and Stafford-Smith, M. "Off-pump versus on-pump coronary artery bypass surgery and postoperative renal dysfunction." Anesth Analg 91, no. 5 (November 2000): 1080-1084. Link to Item
  - Stafford-Smith, M, Phillips-Bute, B, Reddan, DN, Black, J, and Newman, MF. "The association of epsilon-aminocaproic acid with postoperative decrease in creatinine clearance in 1502 coronary bypass patients." Anesth Analg 91, no. 5 (November 2000): 1085-1090. Link to Item
  - Kilts, JD, Gerhardt, MA, Richardson, MD, Sreeram, G, Mackensen, GB, Grocott, HP, White, WD, Davis, RD, Newman, MF, Reves, JG, Schwinn, DA, and Kwatra, MM. "Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i)." Circ Res 87, no. 8 (October 13, 2000): 705-709. Link to Item
  - Kilts, JD, Gerhardt, MA, Richardson, MD, Sreeram, G, Mackensen, GB, Grocott, HP, White, WD, Davis, RD, Newman, MF, Reves, JG, Schwinn, DA, and Kwatra, MM. "β2-Adrenergic and several other g protein-coupled receptors in human atrial membranes activate both G(s) and G(i)." Circulation Research 87, no. 8 (October 13, 2000): 705-709. Full Text
  - Chew, ST, Newman, MF, White, WD, Conlon, PJ, Saunders, AM, Strittmatter, WJ, Landolfo, K, Grocott, HP, and Stafford-Smith, M. "Preliminary report on the association of apolipoprotein E polymorphisms, with postoperative peak serum creatinine concentrations in cardiac surgical patients." Anesthesiology 93, no. 2 (August 2000): 325-331. Link to Item
  - Newman, MF, Stanley, TO, and Grocott, HP. "Strategies to Protect the Brain During Cardiac Surgery." Seminars in Cardiothoracic and Vascular Anesthesia 4, no. 2 (July 2000): 53-64. Full Text
  - Hill, SE, van Wermeskerken, GK, Lardenoye, JW, Phillips-Bute, B, Smith, PK, Reves, JG, and Newman, MF. "Intraoperative physiologic variables and outcome in cardiac surgery: Part I. In-hospital mortality." Ann Thorac Surg 69, no. 4 (April 2000): 1070-1075. Link to Item
  - van Wermeskerken, GK, Lardenoye, JW, Hill, SE, Grocott, HP, Phillips-Bute, B, Smith, PK, Reves, JG, and Newman, MF. "Intraoperative physiologic variables and outcome in cardiac surgery: Part II. Neurologic outcome." Ann Thorac Surg 69, no. 4 (April 2000): 1077-1083. Link to Item
  - Arrowsmith, JE, Grocott, HP, Reves, JG, and Newman, MF. "Central nervous system complications of cardiac surgery." British Journal of Anaesthesia 84, no. 3 (March 2000): 378-393. (Review) Full Text
  - Arrowsmith, JE, Grocott, HP, Reves, JG, Newman, MF, and Levy, F. "Central nervous system complications of cardiac surgery." Cahiers D'Anesthesiologie 48, no. 3 (January 1, 2000): 233-240.
  - Kilts, JD, Gerhardt, MA, Richardson, MD, Sreeram, G, Mackensen, GB, Grocott, HP, White, WD, Davis, RD, Newman, MF, Reves, JG, Schwinn, DA, and Kwatra, MM. "β₂-Adrenergic and several other g protein-coupled receptors in human atrial membranes activate both G(s) and G(i)." Circulation Research 87, no. 8 (2000): 705-709.
  - Arrowsmith, JE, Grocott, HP, and Newman, MF. "Neurologic risk assessment, monitoring and outcome in cardiac surgery." J Cardiothorac Vasc Anesth 13, no. 6 (December 1999): 736-743. (Review) Link to Item
  - Glower, DD, Komtebedde, J, Clements, FM, Debruijn, NP, Stafford-Smith, M, and Newman, MF. "Direct aortic cannulation for port-access mitral or coronary artery bypass grafting." Ann Thorac Surg 68, no. 5 (November 1999): 1878-1880. Link to Item
  - Grichnik, KP, Ijsselmuiden, AJ, D'Amico, TA, Harpole, DH, White, WD, Blumenthal, JA, and Newman, MF. "Cognitive decline after major noncardiac operations: a preliminary prospective study." The Annals of Thoracic Surgery 68, no. 5 (November 1999): 1786-1791. Full Text
  - Bennett-Guerrero, E, Welsby, I, Dunn, TJ, Young, LR, Wahl, TA, Diers, TL, Phillips-Bute, BG, Newman, MF, and Mythen, MG. "The use of a postoperative morbidity survey to evaluate patients with prolonged hospitalization after routine, moderate-risk, elective surgery." Anesth Analg 89, no. 2 (August 1999): 514-519. Link to Item
  - Bennett-Guerrero, E, Spillane, WF, White, WD, Muhlbaier, LH, Gall, SA, Smith, PK, and Newman, MF. "Epsilon-aminocaproic acid administration and stroke following coronary artery bypass graft surgery." Ann Thorac Surg 67, no. 5 (May 1999): 1283-1287. Link to Item
  - Bennett-Guerrero, E, Spillane, WF, White, WD, Muhlbaier, LH, Gall, SA, Smith, PK, and Newman, MF. "ε-Aminocaproic acid administration and stroke following coronary artery bypass graft surgery." Annals of Thoracic Surgery 67, no. 5 (May 1, 1999): 1283-1287. Full Text
  - Conlon, PJ, Stafford-Smith, M, White, WD, Newman, MF, King, S, Winn, MP, and Landolfo, K. "Acute renal failure following cardiac surgery." Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association European Renal Association 14, no. 5 (May 1999): 1158-1162. Full Text
  - Khatri, P, Babyak, M, Clancy, C, Davis, R, Croughwell, N, Newman, M, Reves, JG, Mark, DB, and Blumenthal, JA. "Perception of cognitive function in older adults following coronary artery bypass surgery." Health Psychol 18, no. 3 (May 1999): 301-306. Link to Item
  - Roach, GW, Newman, MF, Murkin, JM, Martzke, J, Ruskin, A, Li, J, Guo, A, Wisniewski, A, and Mangano, DT. "Ineffectiveness of burst suppression therapy in mitigating perioperative cerebrovascular dysfunction. Multicenter Study of Perioperative Ischemia (McSPI) Research Group." Anesthesiology 90, no. 5 (May 1999): 1255-1264. Full Text
  - Roach, GW, Newman, MF, Murkin, JM, Martzke, J, Ruskin, A, Li, J, Guo, A, Wisniewski, A, and Mangano, DT. "Ineffectiveness of burst suppression therapy in mitigating perioperative cerebrovascular dysfunction." Anesthesiology 90, no. 5 (May 1, 1999): 1255-1264. Full Text
  - Newman, MF, Laskowitz, DT, Saunders, AM, Grigore, AM, and Grocott, HP. "Genetic Predictors of Perioperative Neurologic and Neuropsychological Injury and Recovery." Seminars in Cardiothoracic and Vascular Anesthesia 3, no. 1 (March 1999): 34-46. Full Text
  - Wolman, RL, Nussmeier, NA, Aggarwal, A, Kanchuger, MS, Roach, GW, Newman, MF, Mangano, CM, Marschall, KE, Ley, C, Boisvert, DM, Ozanne, GM, Herskowitz, A, Graham, SH, and Mangano, DT. "Cerebral injury after cardiac surgery: identification of a group at extraordinary risk. Multicenter Study of Perioperative Ischemia Research Group (McSPI) and the Ischemia Research Education Foundation (IREF) Investigators." Stroke 30, no. 3 (March 1999): 514-522. Full Text
  - Wolman, RL, Nussmeier, NA, Aggarwal, A, Kanchuger, MS, Roach, GW, Newman, MF, Mora Mangano, C, Marschall, KE, Ley, C, Boisvert, DM, Ozanne, GM, Herskowitz, A, Graham, SH, and Mangano, DT. "Cerebral injury after cardiac surgery: Identification of a group at extraordinary risk." Stroke 30, no. 3 (January 1, 1999): 514-522. Full Text
  - Grocott, HP, and Newman, MF. "Temperature measurement during cardiac surgery." Can J Anaesth 45, no. 11 (November 1998): 1133-1134. (Letter) Full Text Link to Item
  - Atwell, DM, Grichnik, KP, Newman, MF, Reves, JG, and McBride, WT. "Balance of proinflammatory and antiinflammatory cytokines at thoracic cancer operation." Ann Thorac Surg 66, no. 4 (October 1998): 1145-1150. Link to Item
  - Weiss, L, Grocott, HP, Rosania, RA, Friedman, A, Newman, MF, and Warner, DS. "Case 4--1998. Cardiopulmonary bypass and hypothermic circulatory arrest for basilar artery aneurysm clipping." J Cardiothorac Vasc Anesth 12, no. 4 (August 1998): 473-479. Link to Item
  - Grocott, HP, Croughwell, ND, Amory, DW, White, WD, Kirchner, JL, and Newman, MF. "Cerebral emboli and serum S100beta during cardiac operations." Ann Thorac Surg 65, no. 6 (June 1998): 1645-1649. Link to Item
  - Croughwell, ND, Reves, JG, White, WD, Grocott, HP, Baldwin, BI, Clements, FM, Davis, RD, Jones, RH, and Newman, MF. "Cardiopulmonary bypass time does not affect cerebral blood flow." Ann Thorac Surg 65, no. 5 (May 1998): 1226-1230. Link to Item
  - Newman, MF, Croughwell, ND, White, WD, Sanderson, I, Spillane, W, and Reves, JG. "Pharmacologic electroencephalographic suppression during cardiopulmonary bypass: a comparison of thiopental and isoflurane." Anesth Analg 86, no. 2 (February 1998): 246-251. Link to Item
  - Grocott, HP, Amory, DW, Lowry, E, Croughwell, ND, and Newman, MF. "Transcranial Doppler blood flow velocity versus 133Xe clearance cerebral blood flow during mild hypothermic cardiopulmonary bypass." J Clin Monit Comput 14, no. 1 (January 1998): 35-39. Link to Item
  - Bennett-Guerrero, E, Sorohan, JG, Gurevich, ML, Kazanjian, PE, Levy, RR, Barberá, AV, White, WD, Slaughter, TF, Sladen, RN, Smith, PK, and Newman, MF. "Cost-benefit and efficacy of aprotinin compared with epsilon-aminocaproic acid in patients having repeated cardiac operations: a randomized, blinded clinical trial." Anesthesiology 87, no. 6 (December 1997): 1373-1380. Link to Item
  - Hlatky, MA, Bacon, C, Boothroyd, D, Mahanna, E, Reves, JG, Newman, MF, Johnstone, I, Winston, C, Brooks, MM, Rosen, AD, Mark, DB, Pitt, B, Rogers, W, Ryan, T, Wiens, R, and Blumenthal, JA. "Cognitive function 5 years after randomization to coronary angioplasty or coronary artery bypass graft surgery." Circulation 96, no. 9 Suppl (November 4, 1997): II-11-4-. Link to Item
  - Grocott, HP, Amory, DW, Lowry, E, Newman, MF, Lowe, JE, and Clements, FM. "Cerebral embolization during transmyocardial laser revascularization." J Thorac Cardiovasc Surg 114, no. 5 (November 1997): 856-858. Full Text Link to Item
  - Grichnik, KP, Newman, MF, and Reves, JG. "The aging central nervous system." Problems in Anesthesia 9, no. 4 (October 1, 1997): 513-524.
  - Newman, MF, and Reves, JG. "Feeling the heat." J Cardiothorac Vasc Anesth 11, no. 6 (October 1997): 687-688. Link to Item
  - Reves, JG, Sladen, RN, and Newman, MF. "CACI in cardiac surgery." Anesthesiology 87, no. 4 (October 1997): 1015-. (Letter) Link to Item
  - Tardiff, BE, Newman, MF, Saunders, AM, Strittmatter, WJ, Blumenthal, JA, White, WD, Croughwell, ND, Davis, RD, Roses, AD, and Reves, JG. "Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center." Ann Thorac Surg 64, no. 3 (September 1997): 715-720. Link to Item
  - Bennett-Guerrero, E, Sorohan, JG, Canada, AT, Ayuso, L, Newman, MF, Reves, JG, and Mythen, MG. "epsilon-Aminocaproic acid plasma levels during cardiopulmonary bypass." Anesth Analg 85, no. 2 (August 1997): 248-251. Link to Item
  - Bennett-Guerrero, E, Sorohan, JG, Canada, AT, Ayuso, L, Newman, MF, Reves, JG, and Mythen, MG. "ε-Aminocaproic acid plasma levels during cardiopulmonary bypass." Anesthesia and Analgesia 85, no. 2 (August 1, 1997): 248-251. Full Text
  - Grocott, HP, Newman, MF, Croughwell, ND, White, WD, Lowry, E, and Reves, JG. "Continuous jugular venous versus nasopharyngeal temperature monitoring during hypothermic cardiopulmonary bypass for cardiac surgery." J Clin Anesth 9, no. 4 (June 1997): 312-316. Link to Item
  - Grocott, HP, Newman, MF, Lowe, JE, and Clements, F. "Transmyocardial laser revascularization: an anesthetic perspective." J Cardiothorac Vasc Anesth 11, no. 2 (April 1997): 206-210. (Review) Link to Item
  - Bennett-Guerrero, E, Ayuso, L, Hamilton-Davies, C, White, WD, Barclay, GR, Smith, PK, King, SA, Muhlbaier, LH, Newman, MF, and Mythen, MG. "Relationship of preoperative antiendotoxin core antibodies and adverse outcomes following cardiac surgery." Jama 277, no. 8 (February 1997): 646-650. Full Text
  - Newman, MF, and Reves, JG. "Toward a new frontier in cardiac surgery." Ann Thorac Surg 63, no. 2 (February 1997): 322-323. Link to Item
  - Croughwell, ND, Newman, MF, Lowry, E, Davis, RD, Landolfo, KP, White, WD, Kirchner, JL, and Mythen, MG. "Effect of temperature during cardiopulmonary bypass on gastric mucosal perfusion." Br J Anaesth 78, no. 1 (January 1997): 34-38. Link to Item
  - Reves, JG, Sladen, RN, Newman, MF, and Jain, U. "CACl in cardiac surgery [8] (multiple letters)." Anesthesiology 87, no. 4 (January 1, 1997): 1015-null. (Letter)
  - Bennett-Guerrero, E, Sorohan, JG, Howell, ST, Ayuso, L, Cardigan, RA, Newman, MF, Mackie, IJ, Reves, JG, and Mythen, MG. "Maintenance of therapeutic plasma aprotinin levels during prolonged cardiopulmonary bypass using a large-dose regimen." Anesth Analg 83, no. 6 (December 1996): 1189-1192. Link to Item
  - Roach, GW, Kanchuger, M, Mangano, CM, Newman, M, Nussmeier, N, Wolman, R, Aggarwal, A, Marschall, K, Graham, SH, and Ley, C. "Adverse cerebral outcomes after coronary bypass surgery. Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators." The New England Journal of Medicine 335, no. 25 (December 1996): 1857-1863. Full Text
  - Newman, MF, Croughwell, ND, White, WD, Lowry, E, Baldwin, BI, Clements, FM, Davis, RD, Jones, RH, Amory, DW, and Reves, JG. "Effect of perfusion pressure on cerebral blood flow during normothermic cardiopulmonary bypass." Circulation 94, no. 9 Suppl (November 1, 1996): II353-II357. Link to Item
  - Newman, MF, Croughwell, ND, White, WD, Lowry, E, Baldwin, BI, Clements, FM, Davis, RD, Jones, RH, Amory, DW, and Reves, JG. "Effect of perfusion pressure on cerebral blood flow during normothermic cardiopulmonary bypass." Circulation 94, no. 9 SUPPL. (November 1, 1996).
  - Newman, MF, Wolman, R, Kanchuger, M, Marschall, K, Mora-Mangano, C, Roach, G, Smith, LR, Aggarwal, A, Nussmeier, N, Herskowitz, A, and Mangano, DT. "Multicenter preoperative stroke risk index for patients undergoing coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group." Circulation 94, no. 9 Suppl (November 1, 1996): II74-II80. Link to Item
  - Newman, MF, Wolman, R, Kanchuger, M, Marschall, K, Mora-Mangano, C, Roach, G, Smith, LR, Aggarwal, A, Nussmeier, N, Herskowitz, A, and Mangano, DT. "Multicenter preoperative stroke risk index for patients undergoing coronary artery bypass graft surgery." Circulation 94, no. 9 SUPPL. (November 1, 1996).
  - Jones, RH, Kesler, K, Phillips, HR, Mark, DB, Smith, PK, Nelson, CL, Newman, MF, Reves, JG, Anderson, RW, and Califf, RM. "Long-term survival benefits of coronary artery bypass grafting and percutaneous transluminal angioplasty in patients with coronary artery disease." The Journal of Thoracic and Cardiovascular Surgery 111, no. 5 (May 1996): 1013-1025. Full Text
  - Mahanna, EP, Blumenthal, JA, White, WD, Croughwell, ND, Clancy, CP, Smith, LR, and Newman, MF. "Defining neuropsychological dysfunction after coronary artery bypass grafting." Ann Thorac Surg 61, no. 5 (May 1996): 1342-1347. (Review) Link to Item
  - Newman, MF, Croughwell, ND, Blumenthal, JA, Lowry, E, White, WD, and Reves, JG. "Cardiopulmonary bypass and the central nervous system: potential for cerebral protection." J Clin Anesth 8, no. 3 Suppl (May 1996): 53S-60S. (Review) Link to Item
  - Kern, FH, Ungerleider, RM, Schulman, SR, Meliones, JN, Schell, RM, Baldwin, B, Hickey, PR, Newman, MF, Jonas, RA, and Greeley, WJ. "Comparing two strategies of cardiopulmonary bypass cooling on jugular venous oxygen saturation in neonates and infants." Ann Thorac Surg 60, no. 5 (November 1995): 1198-1202. Full Text Link to Item
  - Reves, JG, Sladen, RN, and Newman, MF. "Cardiac anesthetic: is it unique?." Anesth Analg 81, no. 5 (November 1995): 895-896. Link to Item
  - Newman, MF, Murkin, JM, Roach, G, Croughwell, ND, White, WD, Clements, FM, and Reves, JG. "Cerebral physiologic effects of burst suppression doses of propofol during nonpulsatile cardiopulmonary bypass. CNS Subgroup of McSPI." Anesth Analg 81, no. 3 (September 1995): 452-457. Link to Item
  - Newman, MF, Kramer, D, Croughwell, ND, Sanderson, I, Blumenthal, JA, White, WD, Smith, LR, Towner, EA, and Reves, JG. "Differential age effects of mean arterial pressure and rewarming on cognitive dysfunction after cardiac surgery." Anesth Analg 81, no. 2 (August 1995): 236-242. Link to Item
  - Croughwell, ND, White, WD, Smith, LR, Davis, RD, Glower, DD, Reves, JG, and Newman, MF. "Jugular bulb saturation and mixed venous saturation during cardiopulmonary bypass." Journal of Cardiac Surgery 10, no. 4 Suppl (July 1995): 503-508. Full Text
  - Blumenthal, JA, Mahanna, EP, Madden, DJ, White, WD, Croughwell, ND, and Newman, MF. "Methodological issues in the assessment of neuropsychologic function after cardiac surgery." The Annals of Thoracic Surgery 59, no. 5 (May 1995): 1345-1350. (Review) Full Text
  - Newman, MF, Croughwell, ND, Blumenthal, JA, Lowry, E, White, WD, Spillane, W, Davis, RD, Glower, DD, Smith, LR, and Mahanna, EP. "Predictors of cognitive decline after cardiac operation." Ann Thorac Surg 59, no. 5 (May 1995): 1326-1330. Link to Item
  - Young, WL, Newman, MF, Amory, D, and Reves, JG. "Cerebral blood flow values during cardiopulmonary bypass: relatively absolute or absolutely relative?." Ann Thorac Surg 59, no. 3 (March 1995): 558-561. Full Text Link to Item
  - Burker, EJ, Blumenthal, JA, Feldman, M, Burnett, R, White, W, Smith, LR, Croughwell, N, Schell, R, Newman, M, and Reves, JG. "Depression in male and female patients undergoing cardiac surgery." Br J Clin Psychol 34 ( Pt 1) (February 1995): 119-128. Link to Item
  - Burker, EJ, Blumenthal, JA, Feldman, M, Thyrum, E, Mahanna, E, White, W, Smith, LR, Lewis, J, Croughwell, N, and Schell, R. "The Mini Mental State Exam as a predictor of neuropsychological functioning after cardiac surgery." International Journal of Psychiatry in Medicine 25, no. 3 (January 1995): 263-276. Full Text
  - Croughwell, ND, White, WD, Smith, LR, Davis, RD, Jr, DDG, Reves, JG, and Newman, MF. "Jugular Bulb Saturation and Mixed Venous Saturation During Cardiopulmonary Bypass." Journal of Cardiac Surgery 10 (January 1, 1995): 503-508. Full Text
  - Mutch, WAC, Newman, MF, Croughwell, ND, and Reves, JG. "Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass [6]." Annals of Thoracic Surgery 60, no. 1 (1995): 231-232.
  - Newman, MF, Croughwell, ND, and Reves, JG. "Reply." The Annals of Thoracic Surgery 60, no. 1 (January 1, 1995): 231-232. (Letter) Full Text
  - Croughwell, ND, Newman, MF, Blumenthal, JA, White, WD, Lewis, JB, Frasco, PE, Smith, LR, Thyrum, EA, Hurwitz, BJ, and Leone, BJ. "Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass." Ann Thorac Surg 58, no. 6 (December 1994): 1702-1708. Link to Item
  - Newman, MF, Croughwell, ND, Blumenthal, JA, White, WD, Lewis, JB, Smith, LR, Frasco, P, Towner, EA, Schell, RM, Hurwitz, BJ, and Reves, JG. "Effect of aging on cerebral autoregulation during cardiopulmonary bypass: Association with postoperative cognitive dysfunction." Circulation 90, no. 5 II (November 1, 1994).
  - Newman, MF, Croughwell, ND, Blumenthal, JA, White, WD, Lewis, JB, Smith, LR, Frasco, P, Towner, EA, Schell, RM, and Hurwitz, BJ. "Effect of aging on cerebral autoregulation during cardiopulmonary bypass. Association with postoperative cognitive dysfunction." Circulation 90, no. 5 Pt 2 (November 1994): II243-II249. Link to Item
  - Olthoff, D, Deutrich, C, Newman, MF, Schell, RM, and Reves, JG. "Monitoring the jugular-venous oxyhemoglobin saturation as a decision aid for normothermic cardiopulmonary bypass [1]." Anesthesia and Analgesia 78, no. 2 (1994): 403-405.
  - Schell, RM, Kern, FH, Greeley, WJ, Schulman, SR, Frasco, PE, Croughwell, ND, Newman, M, and Reves, JG. "Cerebral blood flow and metabolism during cardiopulmonary bypass." Anesth Analg 76, no. 4 (April 1993): 849-865. (Review) Link to Item
  - Mather, CMP, Anaes, FC, Ready, LB, and Newman, M. "Inflammatory cutaneous reactions to epidural catheters." Anesthesiology 78, no. 1 (1993): 200-203.
  - Newman, M, and Reves, JG. "Midazolam is the sedative of choice to supplement narcotic anesthesia. Pro: Midazolam Is the Sedative of Choice to Supplement Narcotic Anesthesia." Journal of Cardiothoracic and Vascular Anesthesia 7, no. 5 (1993): 615-619. Full Text
  - Croughwell, N, Smith, LR, Quill, T, Newman, M, Greeley, W, Kern, F, Lu, J, and Reves, JG. "The effect of temperature on cerebral metabolism and blood flow in adults during cardiopulmonary bypass." J Thorac Cardiovasc Surg 103, no. 3 (March 1992): 549-554. Link to Item
  - Croughwell, N, Lyth, M, Quill, TJ, Newman, M, Greeley, WJ, Smith, LR, and Reves, JG. "Diabetic patients have abnormal cerebral autoregulation during cardiopulmonary bypass." Circulation 82, no. 5 SUPPL. (1990): IV407-IV412.
  - Ti, LK, Mathew, JP, Mackensen, GB, Grocott, HP, Saunders, AM, White, WD, Reves, JG, and Newman, MF. "Erratum: Effect of apolipoprotein E genotype on cerebral autoregulation during cardiopulmonary bypass (Store (July 2000) 32:7 (1514-1519))." Stroke 32, no. 11 (November 24, 2001): 2727-null.
- Book Sections
  - Mackensen, GB, Grocott, HP, and Newman, MF. "Cardiopulmonary bypass and the brain." In Techniques in Extracorporeal Circulation, Fourth Edition, 148-176. January 1, 2004.
- Other Articles
  - Kertai, MD, Li, Y-W, Li, Y-J, Shah, SH, Kraus, WE, Fontes, ML, Stafford-Smith, M, Newman, MF, Podgoreanu, MV, Mathew, JP, and Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team, . "G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers." Circulation. Cardiovascular Genetics 7, no. 5 (October 2014): 625-633. Full Text
  - McDonagh, DL, Mathew, JP, White, WD, Phillips-Bute, B, Laskowitz, DT, Podgoreanu, MV, Newman, MF, and Neurologic Outcome Research Group, . "Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury." Anesthesiology 112, no. 4 (April 2010): 852-859. Full Text
  - Mackensen, GB, Ti, LK, Phillips-Bute, BG, Mathew, JP, Newman, MF, Grocott, HP, and Neurologic Outcome Research Group (NORG), . "Cerebral embolization during cardiac surgery: impact of aortic atheroma burden." Bja: British Journal of Anaesthesia 91, no. 5 (November 2003): 656-661. Full Text
  - Swaminathan, M, McCreath, BJ, Phillips-Bute, BG, Newman, MF, Mathew, JP, Smith, PK, Blumenthal, JA, Stafford-Smith, M, and Perioperative Outcomes Research Group, . "Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction." Anesth Analg 95, no. 1 (July 2002): 1-8. Link to Item
  - Grigore, AM, Grocott, HP, Mathew, JP, Phillips-Bute, B, Stanley, TO, Butler, A, Landolfo, KP, Reves, JG, Blumenthal, JA, Newman, MF, and Neurologic Outcome Research Group of the Duke Heart Center, . "The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery." Anesthesia and Analgesia 94, no. 1 (January 2002): 4-10. Full Text
  - Tardiff, BE, Newman, MF, Saunders, AM, Strittmatter, WJ, Blumenthal, JA, White, WD, Croughwell, ND, Davis, RD, Roses, AD, and Reves, JG. "Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center." The Annals of Thoracic Surgery 64, no. 3 (September 1997): 715-720. Full Text

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