Scholars@Duke
Nicholas Said

Nicholas Said

Assistant Professor of Radiology
Radiology
nicholas.said@duke.edu
2301 Erwin Rd, DUMC Box 3808, Durham, NC 27710

Selected Publications

ACR Appropriateness Criteria® Stress (Fatigue-Insufficiency) Fracture Including Sacrum Excluding Other Vertebrae: 2024 Update.

Journal Article J Am Coll Radiol · November 2024 Stress fractures, including both fatigue and insufficiency types, are frequently encountered in clinical practice as a source of pain in a variety of patients (athletes, older patients, and patients with predisposing conditions). Radiography is the imaging ... Full text Link to item Cite

ACR Appropriateness Criteria® Chronic Hand and Wrist Pain: 2023 Update.

Journal Article J Am Coll Radiol · June 2024 Chronic hand and wrist pain is a common presenting complaint. The intricate anatomy results in a variety of pain generators-multiple bones, articular cartilage, intrinsic ligaments, triangular fibrocartilage complex, joint capsules and synovium, tendons an ... Full text Link to item Cite

Quick Guide: Programming a Gaming Keyboard for PACS to Optimize Radiology Workflow.

Journal Article Curr Probl Diagn Radiol · 2024 The surging demand for diagnostic imaging has highlighted inefficiencies with traditional input devices. Radiologists, using conventional mice and keyboards, grapple with cumbersome shortcuts leading to fatigue, errors, and possible injuries. Gaming keyboa ... Full text Link to item Cite

ACR Appropriateness Criteria® Imaging After Total Knee Arthroplasty: 2023 Update.

Journal Article J Am Coll Radiol · November 2023 Total knee arthroplasty is the most commonly performed joint replacement procedure in the United States. This manuscript will discuss the recommended imaging modalities for six clinical variants; 1. follow-up of symptomatic or asymptomatic patients with a ... Full text Link to item Cite

ACR Appropriateness Criteria® Imaging After Total Hip Arthroplasty.

Journal Article J Am Coll Radiol · November 2023 This article reviews evidence for performing various imaging studies in patients with total hip prostheses. Routine follow-up is generally performed with radiography. Radiographs are also usually the initial imaging modality for patients with symptoms rela ... Full text Link to item Cite

Facets of facet joint interventions.

Journal Article Skeletal Radiol · October 2023 Facet joint (FJ) disease is a common cause of axial low back pain with many minimally invasive image-guided treatment options. This article discusses fluoroscopic and CT-guided intraarticular FJ injections, medial branch (MB) radiofrequency ablation (RFA), ... Full text Link to item Cite

ACR Appropriateness Criteria® Chronic Shoulder Pain: 2022 Update.

Journal Article J Am Coll Radiol · May 2023 Chronic shoulder pain is an extremely common presenting complaint. Potential pain generators include the rotator cuff tendons, biceps tendon, labrum, glenohumeral articular cartilage, acromioclavicular joint, bones, suprascapular and axillary nerves, and t ... Full text Link to item Cite

ACR Appropriateness Criteria® Chronic Hip Pain: 2022 Update.

Journal Article J Am Coll Radiol · May 2023 Chronic hip pain is a frequent chief complaint for adult patients who present for evaluation in a variety of clinical practice settings. Following a targeted history and physical examination, imaging plays a vital role in elucidating the etiologies of a pa ... Full text Link to item Cite

ACR Appropriateness Criteria® Chronic Extremity Joint Pain-Suspected Inflammatory Arthritis, Crystalline Arthritis, or Erosive Osteoarthritis: 2022 Update.

Journal Article J Am Coll Radiol · May 2023 Evaluation for suspected inflammatory arthritis as a cause for chronic extremity joint pain often relies on imaging. It is essential that imaging results are interpreted in the context of clinical and serologic results to add specificity because there is s ... Full text Link to item Cite

Quick Guide: Programming a Gaming Mouse for PACS to Optimize Radiology Workflow.

Journal Article Curr Probl Diagn Radiol · 2023 The increasing demand for diagnostic imaging has added to the radiologists' workload, highlighting the shortcomings of conventional computer mice. Radiologists grapple with inefficiencies from frequent mouse clicks and keyboard shortcuts required for vario ... Full text Link to item Cite

Prospective Multireader Evaluation of Photon-counting CT for Multiple Myeloma Screening.

Journal Article Radiol Imaging Cancer · November 2022 Purpose To determine whether photon-counting CT (PCCT) acquisition of whole-body CT images provides similar quantitative image quality and reader satisfaction for multiple myeloma screening at lower radiation doses than does standard energy-integrating det ... Full text Link to item Cite

ACR Appropriateness Criteria® Osteoporosis and Bone Mineral Density: 2022 Update.

Journal Article J Am Coll Radiol · November 2022 Osteoporosis constitutes a significant public health risk. An estimated 10.2 million adults in the United States >50 years of age have osteoporosis, a systemic condition that weakens the bones increasing the susceptibility for fractures. Approximately one- ... Full text Link to item Cite

Optimizing radiologist productivity and efficiency: Work smarter, not harder.

Journal Article Eur J Radiol · October 2022 Radiologists' personal productivity and efficiency are critically important for both improving patient outcomes and protecting clinician well-being. There are several solutions that individuals can implement to improve personal productivity and efficiency ... Full text Link to item Cite

A Reliability Study of Multiplanar Radiographs for the Evaluation of SNAC Wrist Arthritis.

Journal Article Hand (N Y) · May 2022 Background: Scaphoid nonunion advanced collapse (SNAC) is a common form of wrist arthritis, the treatment of which depends on the arthritic stage. The Vender classification serves to describe SNAC arthritis based on a single posteroanterior (PA) radiograph ... Full text Link to item Cite

ACR Appropriateness Criteria® Imaging After Shoulder Arthroplasty: 2021 Update.

Journal Article J Am Coll Radiol · May 2022 Shoulder arthroplasty is a common orthopedic procedure with a complication rate reported to be as high as 39.8% and revision rates as high as 11%. Symptoms related to postoperative difficulties include activity-related pain, decreased range of motion, and ... Full text Link to item Cite

Deep learning-based algorithm for assessment of knee osteoarthritis severity in radiographs matches performance of radiologists.

Journal Article Comput Biol Med · June 2021 UNLABELLED: A fully-automated deep learning algorithm matched performance of radiologists in assessment of knee osteoarthritis severity in radiographs using the Kellgren-Lawrence grading system. PURPOSE: To develop an automated deep learning-based algorith ... Full text Link to item Cite

Moving Radiology Workflow to the Electronic Health Record: Quantitative and Qualitative Experience From a Large Academic Medical Center.

Journal Article Acad Radiol · February 2020 RATIONALE AND OBJECTIVES: To objectively and subjectively evaluate a large, academic radiology department's transition to electronic health record (EHR) centered workflow. MATERIALS AND METHODS: Multiple metrics were compared from before and after the move ... Full text Link to item Cite

Automatic Kellgren-Lawrence grade estimation driven deep learning algorithms

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2020 Knee osteoarthritis (OA) is a prevalent and disabling degenerative joint disease. Objectively identifying knee OA severity is challenging given significant inter-reader variability due to human interpretation factors. The Kellgren-Lawrence (KL) grading sys ... Full text Cite

Automatic estimation of knee joint space narrowing by deep learning segmentation algorithms

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2020 Evaluating the severity of knee osteoarthritis (OA) accounts for significant plain film workload and is a crucial component of knee radiograph interpretation, which informs surgical decision-making for costly and invasive procedures such as knee replacemen ... Full text Cite

Percutaneous image-guided bone biopsy of osteomyelitis in the foot and pelvis has a low impact on guiding antibiotics management: a retrospective analysis of 60 bone biopsies.

Journal Article Skeletal Radiol · September 2019 OBJECTIVE: Image-guided percutaneous bone biopsy may be requested by clinicians to guide antibiotics management decisions in patients with extremity osteomyelitis. Much of the clinical literature describes a high rate of bone biopsy culture positivity in p ... Full text Link to item Cite

Incidence of gadolinium or fluid signal within surgically proven glenoid labral tears at MR arthrography.

Journal Article Skeletal Radiol · August 2019 OBJECTIVE: To determine how often patients with surgically proven labral tears have labral signal on shoulder MR arthrography (MRA) that is not equal to gadolinium or fluid on T1- and T2-weighted images, respectively. MATERIALS AND METHODS: Consecutive pat ... Full text Link to item Cite

Magnetic resonance imaging features of pubic symphysis urinary fistula with pubic bone osteomyelitis in the treated prostate cancer patient.

Journal Article Abdom Radiol (NY) · April 2019 INTRODUCTION: Pubic bone osteomyelitis with pubic symphysis urinary fistula represents a debilitating complication of radiation and ablative treatments for prostate cancer. The definitive radiographic diagnosis of this clinical entity is not described. In ... Full text Link to item Cite

The Value of MRI in Distinguishing Subtypes of Lipomatous Extremity Tumors Needs Reassessment in the Era of MDM2 and CDK4 Testing.

Journal Article Sarcoma · 2018 INTRODUCTION: Extremity lipomas and well-differentiated liposarcomas (WDLs) are difficult to distinguish on MR imaging. We sought to evaluate the accuracy of MRI interpretation using MDM2 amplification, via fluorescence in-situ hybridization (FISH), as the ... Full text Link to item Cite

Correlation of diffusion tensor tractography and intraoperative macrostimulation during deep brain stimulation for Parkinson disease.

Journal Article J Neurosurg · October 2014 OBJECTIVES: The purpose of this study was to investigate whether diffusion tensor imaging (DTI) of the corticospinal tract (CST) is a reliable surrogate for intraoperative macrostimulation through the deep brain stimulation (DBS) leads. The authors hypothe ... Full text Link to item Cite

Dependence of residual dipolar couplings on foot angle in (1)H MR spectra from skeletal muscle.

Journal Article Magn Reson Imaging · May 2014 Foot dorsi and plantar flexion affects the pennation angle of skeletal muscle fibers and changes the fiber direction with respect to the main magnetic field, thereby affecting MR spectrum of the muscle. In order to analyze the effect that foot flexion has ... Full text Link to item Cite

Distinct patterns of fat metabolism in skeletal muscle of normal-weight, overweight, and obese humans.

Journal Article Am J Physiol Regul Integr Comp Physiol · October 2008 The link between body weight, lipid metabolism, and health risks is poorly understood and difficult to study. Magnetic resonance spectroscopy (MRS) permits noninvasive investigation of lipid metabolism. We extended existing two-dimensional MRS techniques t ... Full text Link to item Cite