Recent Publications
Engineered Cardiac Tissues as a Platform for CRISPR-Based Mitogen Discovery.
Journal Article Advanced healthcare materials · January 2025 Improved understanding of cardiomyocyte (CM) cell cycle regulation may allow researchers to stimulate pro-regenerative effects in injured hearts or promote maturation of human stem cell-derived CMs. Gene therapies, in particular, hold promise to induce con ... Full text CiteTime-dependent effects of BRAF-V600E on cell cycling, metabolism, and function in engineered myocardium.
Journal Article Science advances · January 2024 Candidate cardiomyocyte (CM) mitogens such as those affecting the extracellular signal-regulated kinase (ERK) signaling pathway represent potential targets for functional heart regeneration. We explored whether activating ERK via a constitutively active mu ... Full text CiteRecent Grants
Engineering Human Heart Tissues with Polyploid Cardiomyocytes
ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2022 - 2026Investigating the Role of Polyploidy in the Maturation of hiPSC-derived Cardiomyocytes
FellowshipPI-Fellow · Awarded by National Institutes of Health · 2021 - 2024View All Grants