Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Icahn School of Medicine at Mount Sinai 2003
• 

  Previous Appointments & Affiliations

  • Associate Professor of Anesthesiology, Anesthesiology, Neuroanesthesia, Anesthesiology 2018 - 2020
  • Assistant Professor of Anesthesiology, Anesthesiology, Neuroanesthesia, Anesthesiology 2012 - 2018
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Guinn, Nicole R., Jonathon Schwartz, Rakesh C. Arora, Vicki Morton-Bailey, Solomon Aronson, Charles Scott Brudney, Elliott Bennett-Guerrero, and Elliott Perioperative Quality Initiative (POQI-8) and the Enhanced Recovery After Surgery-Cardiac Society (ERAS-C) Investigators. “Perioperative Quality Initiative and Enhanced Recovery After Surgery-Cardiac Society Consensus Statement on the Management of Preoperative Anemia and Iron Deficiency in Adult Cardiac Surgery Patients.” Anesth Analg 135, no. 3 (September 1, 2022): 532–44. https://doi.org/10.1213/ANE.0000000000006148.
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    • Guinn, Nicole R., and Susan M. Goobie. “Patient Blood Management: The Forgotten Element of Enhanced Recovery After Surgery Programs.” Anesth Analg 135, no. 3 (September 1, 2022): 474–75. https://doi.org/10.1213/ANE.0000000000005900.
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    • Shaw, Andrew D., Nicole R. Guinn, Jessica K. Brown, Rakesh C. Arora, Kevin W. Lobdell, Michael C. Grant, Tong J. Gan, Daniel T. Engelman, and Daniel T. Perioperative Quality Initiative (POQI) and Enhanced Recovery after Surgery–Cardiac (ERAS→-Cardiac) investigators. “Controversies in enhanced recovery after cardiac surgery.” Perioper Med (Lond) 11, no. 1 (April 28, 2022): 19. https://doi.org/10.1186/s13741-022-00250-7.
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    • Guinn, Nicole R., Matt Fuller, Sutton Murray, Solomon Aronson, and Solomon Duke Perioperative Enhancement Team (POET). “Treatment through a preoperative anemia clinic is associated with a reduction in perioperative red blood cell transfusion in patients undergoing orthopedic and gynecologic surgery.” Transfusion 62, no. 4 (April 2022): 809–16. https://doi.org/10.1111/trf.16847.
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    • Tan, Hon Sen, Nicole R. Guinn, Matthew E. Fuller, and Ashraf S. Habib. “The association between intravenous iron for antenatal anemia and postnatal depression: a retrospective cohort study.” Arch Gynecol Obstet, February 7, 2022. https://doi.org/10.1007/s00404-022-06417-3.
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    • Guinn, Nicole R., Linda M. S. Resar, and Steven M. Frank. “Perioperative Management of Patients for Whom Transfusion Is Not an Option.” Anesthesiology 134, no. 6 (June 1, 2021): 939–48. https://doi.org/10.1097/ALN.0000000000003763.
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    • Warner, Matthew A., and Nicole R. Guinn. “In Response.” Anesth Analg 132, no. 6 (June 1, 2021): e109–10. https://doi.org/10.1213/ANE.0000000000005493.
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    • Jahr, Jonathan S., Nicole R. Guinn, David R. Lowery, Linda Shore-Lesserson, and Aryeh Shander. “Blood Substitutes and Oxygen Therapeutics: A Review.” Anesth Analg 132, no. 1 (January 2021): 119–29. https://doi.org/10.1213/ANE.0000000000003957.
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    • Merchant, Akeel M., Mark D. Friedland, Marcus A. Behrens, Adam R. Williams, Andrew Berchuck, and Nicole R. Guinn. “Surgical management of ovarian carcinosarcoma with inferior vena cava extension into the right atrium.” J Surg Case Rep 2020, no. 12 (December 2020): rjaa530. https://doi.org/10.1093/jscr/rjaa530.
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    • Weiskopf, Richard B., Elon Glassberg, Nicole R. Guinn, Michael F. M. James, Paul M. Ness, and Anthony E. Pusateri. “The need for an artificial oxygen carrier for disasters and pandemics, including COVID-19.” Transfusion 60, no. 12 (December 2020): 3039–45. https://doi.org/10.1111/trf.16122.
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    • Murillo-Berlioz, Alejandro, Nicole R. Guinn, Jerrold H. Levy, and Carmelo A. Milano. “Arterial and venous thrombosis complicating coronary artery bypass grafting after use of epoetin alfa-epbx.” Jtcvs Tech 4 (December 2020): 154–55. https://doi.org/10.1016/j.xjtc.2020.07.018.
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    • Guinn, Nicole R., Mary L. Cooter, Yasmin Maisonave, Aime Grimsley, Cindy Cellura, Chad A. Grotegut, Agnes Lamon, Solomon Aronson, and Solomon Duke Perioperative Enhancement Team (POET). “How do I develop a process to effectively treat parturients with iron deficiency anemia?” Transfusion 60, no. 11 (November 2020): 2476–81. https://doi.org/10.1111/trf.15930.
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    • Seay, Theresa, Nicole Guinn, Yasmin Maisonave, Matt Fuller, Jessica Poisson, Angela Pollak, Ben Bryner, et al. “The Association of Increased FFP:RBC Transfusion Ratio to Primary Graft Dysfunction in Bleeding Lung Transplantation Patients.” J Cardiothorac Vasc Anesth 34, no. 11 (November 2020): 3024–32. https://doi.org/10.1053/j.jvca.2020.05.043.
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    • Jones, E., A. N. Rice, N. R. Guinn, and C. A. Vacchiano. “Use of a preoperative screening tool to optimize patients with anemia before cardiac valve procedures.” Medsurg Nursing 29, no. 4 (July 1, 2020): 267–71.
    • Shander, Aryeh, Susan M. Goobie, Matthew A. Warner, Matti Aapro, Elvira Bisbe, Angel A. Perez-Calatayud, Jeannie Callum, et al. “Essential Role of Patient Blood Management in a Pandemic: A Call for Action.” Anesth Analg 131, no. 1 (July 2020): 74–85. https://doi.org/10.1213/ANE.0000000000004844.
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    • Guinn, Nicole R., Mary L. Cooter, and Richard B. Weiskopf. “Lower hemoglobin concentration decreases time to death in severely anemic patients for whom blood transfusion is not an option.” J Trauma Acute Care Surg 88, no. 6 (June 2020): 803–8. https://doi.org/10.1097/TA.0000000000002632.
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    • Warner, Matthew A., Linda Shore-Lesserson, Aryeh Shander, Sephalie Y. Patel, Seth I. Perelman, and Nicole R. Guinn. “Perioperative Anemia: Prevention, Diagnosis, and Management Throughout the Spectrum of Perioperative Care.” Anesth Analg 130, no. 5 (May 2020): 1364–80. https://doi.org/10.1213/ANE.0000000000004727.
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    • Gamble, John F., Cory D. Maxwell, Jeffrey Gaca, Nicole R. Guinn, Brian C. Cho, Steven M. Frank, and Pierre R. Tibi. “Successful Ascending Aorta and Hemiarch Replacement and Aortic Valve Resuspension Via Redo Median Sternotomy Using Hypothermic Circulatory Arrest in a Practicing Jehovah's Witnesses Patient.” J Cardiothorac Vasc Anesth 33, no. 5 (May 2019): 1447–54. https://doi.org/10.1053/j.jvca.2018.12.019.
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    • Tan, Gee Mei, Nicole R. Guinn, Steven M. Frank, and Aryeh Shander. “Proceedings From the Society for Advancement of Blood Management Annual Meeting 2017: Management Dilemmas of the Surgical Patient-When Blood Is Not an Option.” Anesth Analg 128, no. 1 (January 2019): 144–51. https://doi.org/10.1213/ANE.0000000000003478.
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    • Guinn, Nicole R., Mary L. Cooter, Claudia Villalpando, and Richard B. Weiskopf. “Severe anemia associated with increased risk of death and myocardial ischemia in patients declining blood transfusion.” Transfusion 58, no. 10 (October 2018): 2290–96. https://doi.org/10.1111/trf.14768.
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    • Duce, Lorent, Mary L. Cooter, Sharon L. McCartney, Frederick W. Lombard, and Nicole R. Guinn. “Outcomes in Patients Undergoing Cardiac Surgery Who Decline Transfusion and Received Erythropoietin Compared to Patients Who Did Not: A Matched Cohort Study.” Anesth Analg 127, no. 2 (August 2018): 490–95. https://doi.org/10.1213/ANE.0000000000002418.
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    • Aronson, Solomon, Julie Westover, Nicole Guinn, Tracy Setji, Paul Wischmeyer, Padma Gulur, Thomas Hopkins, et al. “A Perioperative Medicine Model for Population Health: An Integrated Approach for an Evolving Clinical Science.” Anesth Analg 126, no. 2 (February 2018): 682–90. https://doi.org/10.1213/ANE.0000000000002606.
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    • Oprea, Adriana D., J Mauricio Del Rio, Mary Cooter, Cynthia L. Green, Jörn A. Karhausen, Patrick Nailer, Nicole R. Guinn, et al. “Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study.” Can J Anaesth 65, no. 1 (January 2018): 46–59. https://doi.org/10.1007/s12630-017-0991-0.
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    • Guinn, Nicole R., and Cory Maxwell. “Encouraging single-unit transfusions: a superior patient blood management strategy?” Transfusion 57, no. 5 (May 2017): 1107–8. https://doi.org/10.1111/trf.14083.
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    • Weiskopf, Richard B., Andrei M. Beliaev, Aryeh Shander, Nicole R. Guinn, Andrew P. Cap, Paul M. Ness, and Toby A. Silverman. “Addressing the unmet need of life-threatening anemia with hemoglobin-based oxygen carriers.” Transfusion 57, no. 1 (January 2017): 207–14. https://doi.org/10.1111/trf.13923.
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    • Guinn, Nicole R., Nathan H. Waldron, Mary L. Cooter, Corinne L. Goldberg, Miklos D. Kertai, Karthik Raghunathan, Nicholas Bandarenko, Maureane Hoffman, and Elliott Bennett-Guerrero. “No association between donor age and recipient outcomes: transfusion of plasma in patients undergoing coronary artery bypass grafting surgery.” Transfusion 56, no. 7 (July 2016): 1723–29. https://doi.org/10.1111/trf.13616.
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    • Mauritz, Amy A., Jennifer E. Dominguez, Nicole R. Guinn, Jennifer Gilner, and Ashraf S. Habib. “Blood-Conservation Strategies in a Blood-Refusal Parturient with Placenta Previa and Placenta Percreta.” A a Case Rep 6, no. 5 (March 1, 2016): 111–13. https://doi.org/10.1213/XAA.0000000000000258.
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    • Guinn, Nicole R., Jason R. Guercio, Thomas J. Hopkins, Aime Grimsley, Dinesh J. Kurian, Maria I. Jimenez, Michael P. Bolognesi, Rebecca Schroeder, Solomon Aronson, and Solomon Duke Perioperative Enhancement Team (POET). “How do we develop and implement a preoperative anemia clinic designed to improve perioperative outcomes and reduce cost?” Transfusion 56, no. 2 (February 2016): 297–303. https://doi.org/10.1111/trf.13426.
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    • Guinn, Nicole R., Russell S. Roberson, William White, Patricia A. Cowper, Bob Broomer, Carmelo Milano, Antonio Chiricolo, and Steven Hill. “Costs and outcomes after cardiac surgery in patients refusing transfusion compared with those who do not: a case-matched study.” Transfusion 55, no. 12 (December 2015): 2791–98. https://doi.org/10.1111/trf.13246.
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    • Dallas, Torijaun, Ian Welsby, Brandi Bottiger, Carmelo Milano, Mani Daneshmand, and Nicole Guinn. “Bloodless Orthotopic Heart Transplantation in a Jehovah's Witness.” A a Case Rep 4, no. 10 (May 15, 2015): 140–42. https://doi.org/10.1213/XAA.0000000000000067.
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    • McCartney, Sharon, Nicole Guinn, Russell Roberson, Bob Broomer, William White, and Steven Hill. “Jehovah's Witnesses and cardiac surgery: a single institution's experience.” Transfusion 54, no. 10 Pt 2 (October 2014): 2745–52. https://doi.org/10.1111/trf.12696.
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    • Guinn, Nicole R., Bob W. Broomer, William White, William Richardson, and Steven E. Hill. “Comparison of visually estimated blood loss with direct hemoglobin measurement in multilevel spine surgery.” Transfusion 53, no. 11 (November 2013): 2790–94. https://doi.org/10.1111/trf.12119.
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    • Guinn, Nicole R., David L. McDonagh, Cecil O. Borel, David R. Wright, Ali R. Zomorodi, Ciaran J. Powers, David S. Warner, Arthur M. Lam, and Gavin W. Britz. “Adenosine-induced transient asystole for intracranial aneurysm surgery: a retrospective review.” J Neurosurg Anesthesiol 23, no. 1 (January 2011): 35–40. https://doi.org/10.1097/ANA.0b013e3181ef2b11.
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    • Guinn, Nicole, and Andrew D. Shaw. “Invited commentary.” Ann Thorac Surg 90, no. 6 (December 2010): 1943. https://doi.org/10.1016/j.athoracsur.2010.09.014.
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    • Beilin, Y., D. Wax, T. Torrillo, D. Mungall, N. Guinn, J. Henriquez, and D. L. Reich. “A survey of anesthesiologists' and nurses' attitudes toward the implementation of an Anesthesia Information Management System on a labor and delivery floor.” Int J Obstet Anesth 18, no. 1 (January 2009): 22–27. https://doi.org/10.1016/j.ijoa.2008.05.007.
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    • Beilin, Yaakov, Nicole R. Guinn, Howard H. Bernstein, Jeff Zahn, Sabera Hossain, and Carol A. Bodian. “Local anesthetics and mode of delivery: bupivacaine versus ropivacaine versus levobupivacaine.” Anesth Analg 105, no. 3 (September 2007): 756–63. https://doi.org/10.1213/01.ane.0000278131.73472.f4.
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    • Kurian, Dinesh J., Nicole R. Guinn, John Hunting, John F. Gamble, Thomas J. Hopkins, Aime Grimsley, Jason R. Guercio, Michael P. Bolognesi, Rebecca Schroeder, and Solomon Aronson. “Preoperative Blood Management Strategy for Elective Hip and Knee Arthroplasty.” J Healthc Qual 41, no. 6 (n.d.): 376–83. https://doi.org/10.1097/JHQ.0000000000000207.
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  • Book Sections

    • Guinn, N. R. “Cardiopulmonary bypass cases: To hemodilute or not?” In You’re Wrong, I’m Right: Dueling Authors Reexamine Classic Teachings in Anesthesia, 83–84, 2016. https://doi.org/10.1007/978-3-319-43169-7_24.
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  • Conference Papers

    • Najmeh, S., J. Klapper, J. Poisson, M. Fuller, L. Zaffiri, J. Haney, M. Hartwig, et al. “Perioperative Characteristics Associated with Transfusion-Free Lung Transplantation.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S317, 2020. https://doi.org/10.1016/j.healun.2020.01.715.
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