Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Resident, Radiation Oncology, Duke University 2000 - 2004
  • Intern, Internal Medicine, Greater Baltimore Medical Center 1999 - 2000
  • M.D., Johns Hopkins University 1999
  • M.S., Massachusetts Institute of Technology 1995
  • B.S., Massachusetts Institute of Technology 1994
• 

  Duke Appointment History

  • Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2018 - 2020
  • Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2007 - 2018
  • Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2006 - 2007
  • Associate in the Department of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2004 - 2006
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Dial, Brian L., David L. Kerr, Alexander L. Lazarides, Anthony A. Catanzano, Cindy L. Green, Thomas Risoli, Dan G. Blazer, et al. “The Role of Radiotherapy for Chordoma Patients Managed With Surgery: Analysis of the National Cancer Database.” Spine (Phila Pa 1976) 45, no. 12 (June 15, 2020): E742–51. https://doi.org/10.1097/BRS.0000000000003406.
       Full Text  Link to Item
    • Brown, Patrick, Hiroto Inaba, Colleen Annesley, Jill Beck, Susan Colace, Mari Dallas, Kenneth DeSantes, et al. “Pediatric Acute Lymphoblastic Leukemia, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 18, no. 1 (January 2020): 81–112. https://doi.org/10.6004/jnccn.2020.0001.
       Full Text  Link to Item
    • Catanzano, Anthony A., David L. Kerr, Alexander L. Lazarides, Brian L. Dial, Whitney O. Lane, Dan G. Blazer, Nicole A. Larrier, David G. Kirsch, Brian E. Brigman, and William C. Eward. “Revisiting the Role of Radiation Therapy in Chondrosarcoma: A National Cancer Database Study.” Sarcoma 2019 (2019): 4878512. https://doi.org/10.1155/2019/4878512.
       Full Text  Link to Item
    • Leung, Nicole, Adela R. Cardones, and Nicole Larrier. “Long-term improvement of recalcitrant Darier disease with photon and electron beam radiation therapy.” Jaad Case Rep 4, no. 10 (November 2018): 1062–64. https://doi.org/10.1016/j.jdcr.2018.08.017.
       Full Text  Link to Item
    • Leung, Nicole, Adela R. Cardones, and Nicole Larrier. “Long-term improvement of recalcitrant Hailey-Hailey disease with electron beam radiation therapy: Case report and review.” Pract Radiat Oncol 8, no. 5 (September 2018): e259–61. https://doi.org/10.1016/j.prro.2018.02.011.
       Full Text  Link to Item
    • Lee, Andrew R., Dilraj S. Grewal, Thomas J. Cummings, Laura B. Enyedi, Nicole A. Larrier, and Prithvi Mruthyunjaya. “Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy.” J Aapos 21, no. 5 (October 2017): 410–12. https://doi.org/10.1016/j.jaapos.2017.03.014.
       Full Text  Link to Item
    • Larrier, Nicole A., Brian G. Czito, and David G. Kirsch. “Radiation Therapy for Soft Tissue Sarcoma: Indications and Controversies for Neoadjuvant Therapy, Adjuvant Therapy, Intraoperative Radiation Therapy, and Brachytherapy.” Surg Oncol Clin N Am 25, no. 4 (October 2016): 841–60. https://doi.org/10.1016/j.soc.2016.05.012.
       Full Text  Link to Item
    • Whitley, Melodi Javid, Diana M. Cardona, Alexander L. Lazarides, Ivan Spasojevic, Jorge M. Ferrer, Joan Cahill, Chang-Lung Lee, et al. “A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.” Sci Transl Med 8, no. 320 (January 6, 2016): 320ra4. https://doi.org/10.1126/scitranslmed.aad0293.
       Full Text  Link to Item
    • Larrier, N. “Genitourinary,” September 3, 2015, 283–96. https://doi.org/10.1007/978-3-319-16435-9_15.
       Full Text
    • Larrier, Nicole A., David G. Kirsch, Richard F. Riedel, Howard Levinson, William C. Eward, and Brian E. Brigman. “Practical radiation oncology for extremity sarcomas.” Surg Oncol Clin N Am 22, no. 3 (July 2013): 433–43. https://doi.org/10.1016/j.soc.2013.02.004.
       Full Text  Link to Item
    • Craciunescu, Oana I., Beverly A. Steffey, Chris R. Kelsey, Nicole A. Larrier, Cathy J. Paarz-Largay, Robert G. Prosnitz, Nelson Chao, et al. “Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial.” Int J Radiat Oncol Biol Phys 79, no. 4 (March 15, 2011): 1248–55. https://doi.org/10.1016/j.ijrobp.2010.05.036.
       Full Text  Link to Item
    • McMahon, Ryan L., Nicole A. Larrier, and Q Jackie Wu. “An image-guided technique for planning and verification of supine craniospinal irradiation.” J Appl Clin Med Phys 12, no. 2 (January 31, 2011): 3310. https://doi.org/10.1120/jacmp.v12i2.3310.
       Full Text  Link to Item
    • McMahon, R. L., N. A. Larrier, and Q. J. Wu. “An image-guided technique for planning and verification of supine craniospinal irradiation.” Journal of Applied Clinical Medical Physics 12, no. 2 (January 1, 2011): 184–90. https://doi.org/10.1120/jacmp.v12i2.3310.
       Full Text
    • Nelson, John W., David S. Yoo, John H. Sampson, Robert E. Isaacs, Nicole A. Larrier, Lawrence B. Marks, Fang-Fang Yin, Q Jackie Wu, Zhiheng Wang, and John P. Kirkpatrick. “Stereotactic body radiotherapy for lesions of the spine and paraspinal regions.” Int J Radiat Oncol Biol Phys 73, no. 5 (April 1, 2009): 1369–75. https://doi.org/10.1016/j.ijrobp.2008.06.1949.
       Full Text  Link to Item
    • Riedel, Richard F., Nicole Larrier, Leslie Dodd, David Kirsch, Salutario Martinez, and Brian E. Brigman. “The clinical management of chondrosarcoma.” Curr Treat Options Oncol 10, no. 1–2 (April 2009): 94–106. https://doi.org/10.1007/s11864-009-0088-2.
       Full Text  Link to Item
    • Gururangan, Sridharan, Jeanne Krauser, Melody A. Watral, Tim Driscoll, Nicole Larrier, David A. Reardon, Jeremy N. Rich, et al. “Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma.” Neuro Oncol 10, no. 5 (October 2008): 745–51. https://doi.org/10.1215/15228517-2008-044.
       Full Text  Link to Item
    • Miles, Edward F., Nicole A. Larrier, Christopher R. Kelsey, Jessica L. Hubbs, Jinli Ma, Sua Yoo, and Lawrence B. Marks. “Intensity-modulated radiotherapy for resected mesothelioma: the Duke experience.” Int J Radiat Oncol Biol Phys 71, no. 4 (July 15, 2008): 1143–50. https://doi.org/10.1016/j.ijrobp.2007.11.011.
       Full Text  Link to Item
    • Yin, Fang-Fang, Zhiheng Wang, Sua Yoo, Q Jackie Wu, John Kirkpatrick, Nicole Larrier, Jeffrey Meyer, Christopher G. Willett, and Lawrence B. Marks. “Integration of cone-beam CT in stereotactic body radiation therapy.” Technol Cancer Res Treat 7, no. 2 (April 2008): 133–39. https://doi.org/10.1177/153303460800700206.
       Full Text  Link to Item
    • Wang, Zhiheng, Q Jackie Wu, Lawrence B. Marks, Nicole Larrier, and Fang-Fang Yin. “Cone-beam CT localization of internal target volumes for stereotactic body radiotherapy of lung lesions.” Int J Radiat Oncol Biol Phys 69, no. 5 (December 1, 2007): 1618–24. https://doi.org/10.1016/j.ijrobp.2007.08.030.
       Full Text  Link to Item
    • Mao, Jingfang, Zafer Kocak, Sumin Zhou, Jennifer Garst, Elizabeth S. Evans, Junan Zhang, Nicole A. Larrier, Donna R. Hollis, Rodney J. Folz, and Lawrence B. Marks. “The impact of induction chemotherapy and the associated tumor response on subsequent radiation-related changes in lung function and tumor response.” Int J Radiat Oncol Biol Phys 67, no. 5 (April 1, 2007): 1360–69. https://doi.org/10.1016/j.ijrobp.2006.11.003.
       Full Text  Link to Item
    • Larrier, Nicole A., and Lawrence B. Marks. “What radiation dose is safe in patients with non-small-cell lung cancer?” Nat Clin Pract Oncol 4, no. 2 (February 2007): 80–81. https://doi.org/10.1038/ncponc0689.
       Full Text  Link to Item
    • Anscher, Mitchell S., Jennifer Garst, Lawrence B. Marks, Nicole Larrier, Frank Dunphy, James E. Herndon, Robert Clough, et al. “Assessing the ability of the antiangiogenic and anticytokine agent thalidomide to modulate radiation-induced lung injury.” Int J Radiat Oncol Biol Phys 66, no. 2 (October 1, 2006): 477–82. https://doi.org/10.1016/j.ijrobp.2006.05.031.
       Full Text  Link to Item
    • Mazur, Melissa A., Sridharan Gururangan, Julia A. Bridge, Thomas J. Cummings, Srinivasan Mukundan, Herbert Fuchs, Nicole Larrier, and Edward C. Halperin. “Intracranial Ewing sarcoma.” Pediatr Blood Cancer 45, no. 6 (November 2005): 850–56. https://doi.org/10.1002/pbc.20430.
       Full Text  Link to Item
    • Rosoff, Philip M., Nicole Larrier, and Henry E. Rice. “Intra-abdominal desmoid tumor after successful treatment for Hodgkin disease.” Pediatr Blood Cancer 45, no. 5 (October 15, 2005): 728–31. https://doi.org/10.1002/pbc.20288.
       Full Text  Link to Item
    • Anscher, Mitchell S., Liguang Chen, Zahid Rabbani, Song Kang, Nicole Larrier, Hong Huang, Thaddeus V. Samulski, et al. “Recent progress in defining mechanisms and potential targets for prevention of normal tissue injury after radiation therapy.” Int J Radiat Oncol Biol Phys 62, no. 1 (May 1, 2005): 255–59. https://doi.org/10.1016/j.ijrobp.2005.01.040.
       Full Text  Link to Item
    • Chen, Liguang, David M. Brizel, Zahid N. Rabbani, Thaddeus V. Samulski, Catherine L. Farrell, Nicole Larrier, Mitchell S. Anscher, and Zeljko Vujaskovic. “The protective effect of recombinant human keratinocyte growth factor on radiation-induced pulmonary toxicity in rats.” Int J Radiat Oncol Biol Phys 60, no. 5 (December 1, 2004): 1520–29. https://doi.org/10.1016/j.ijrobp.2004.07.729.
       Full Text  Link to Item
    • DeWeese, T. L., J. M. Shipman, N. A. Larrier, N. M. Buckley, L. R. Kidd, J. D. Groopman, R. G. Cutler, H. te Riele, and W. G. Nelson. “Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation.” Proc Natl Acad Sci U S A 95, no. 20 (September 29, 1998): 11915–20. https://doi.org/10.1073/pnas.95.20.11915.
       Full Text  Link to Item

  • Book Sections

    • Larrier, N., W. C. Eward, and R. F. Riedel. “Bone Sarcomas.” In Cancer Consult: Expertise for Clinical Practice, 687–95, 2014. https://doi.org/10.1002/9781118589199.ch105.
       Full Text

  • Conference Papers

    • Craciunescu, O., J. Macfall, B. Soher, P. Stauffer, P. Maccarini, E. Jones, N. Larrier, et al. “WE‐C‐BRC‐02: Combined Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE‐MRI) and Magnetic Resonance Thermal Imaging (MRTI) for Optimal Hyperthermia Treatment of Advanced Extremity Sarcomas: Fifteen Patients Update.” In Medical Physics, 36:2760, 2009. https://doi.org/10.1118/1.3182470.
       Full Text
    • Craciunescu, O., B. Steffey, S. Yoo, N. Larrier, C. Paarz‐largay, K. Sullivan, and R. Prosnitz. “TU‐EE‐A2‐05: Challenges in Limiting Kidney Dose When Delivering Total Body Irradiation (TBI) for Patients with Severe Systemic Sclerosis (SSc).” In Medical Physics, 34:2568, 2007. https://doi.org/10.1118/1.2761426.
       Full Text
    • Wang, Z., J. Nelson, S. Yoo, Q. J. wu, J. Kirkpatrick, N. Larrier, J. Meyer, C. Willett, and F. Yin. “SU‐FF‐T‐252: Improvement of Localization Accuracy by Using 3D Cone Beam CT for Stereotactic Body Radiation Therapy of Liver, Lung and Spine Lesions.” In Medical Physics, 34:2459, 2007. https://doi.org/10.1118/1.2760913.
       Full Text
    • Craciunescu, O., T. Raidy, D. Brizel, K. Blackwell, Z. Vujaskovic, T. Wong, E. Jones, N. Larrier, J. Macfall, and M. Dewhirst. “SU‐FF‐J‐125: Therapy Assessment Using a Full Time Point (fTP) Pharmacokinetic Analysis of Dynamic Contrast‐Enhanced Magnetic Resonance Imaging (DCE‐MRI): Role of Region of Interest (ROI) Selection in Three Tumor Sites.” In Medical Physics, 33:2049, 2006. https://doi.org/10.1118/1.2240901.
       Full Text
    • Yin, F., L. Marks, Z. Wang, J. Kirkpatrick, J. Wu, S. Yoo, N. Larrier, J. Meyer, and C. Willett. “SU‐FF‐T‐66: A Technique for Cone‐Beam CT‐Guided Stereotactic Body Radiation Therapy.” In Medical Physics, 33:2063, 2006. https://doi.org/10.1118/1.2240992.
       Full Text
• Teaching & Mentoring
• 

  Recent Courses

  • RADONC 220C: Brief Experience in Clinical Radiation/Oncology 2021
  • RADONC 415C: Clinical Radiation Oncology 2021
  • RADONC 220C: Brief Experience in Clinical Radiation/Oncology 2020
  • RADONC 415C: Clinical Radiation Oncology 2020
  • RADONC 220C: Brief Experience in Clinical Radiation/Oncology 2019
  • RADONC 415C: Clinical Radiation Oncology 2019

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.