Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Resident, Radiation Oncology, Duke University 2000 - 2004
  • Intern, Internal Medicine, Greater Baltimore Medical Center 1999 - 2000
  • M.D., Johns Hopkins University 1999
  • M.S., Massachusetts Institute of Technology 1995
  • B.S., Massachusetts Institute of Technology 1994
• 

  Duke Appointment History

  • Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2006 - 2007
  • Associate in the Department of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2004 - 2006
• Publications & Artistic Works
• 

  Selected Publications

  • Book Sections

    • Larrier, N, Eward, WC, and Riedel, RF. "Bone Sarcomas." In Cancer Consult: Expertise for Clinical Practice, 687-695. June 20, 2014.  Full Text

  • Conference Papers

    • Craciunescu, O, MacFall, J, Soher, B, Stauffer, P, Maccarini, P, Jones, E, Larrier, N, Wong, T, Carroll, M, Dewhirst, M, and Vujaskovic, Z. "WE-C-BRC-02: Combined Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) and Magnetic Resonance Thermal Imaging (MRTI) for Optimal Hyperthermia Treatment of Advanced Extremity Sarcomas: Fifteen Patients Update." June 2009.  Full Text
    • Craciunescu, O, Steffey, B, Yoo, S, Larrier, N, Paarz-Largay, C, Sullivan, K, and Prosnitz, R. "TU-EE-A2-05: Challenges in Limiting Kidney Dose When Delivering Total Body Irradiation (TBI) for Patients with Severe Systemic Sclerosis (SSc)." June 2007.  Full Text
    • Wang, Z, Nelson, J, Yoo, S, Wu, QJ, Kirkpatrick, J, Larrier, N, Meyer, J, Willett, C, and Yin, F. "Improvement of localization accuracy by using 3D cone beam CT for stereotactic body radiation therapy of liver, lung and spine lesions." June 2007.  Full Text  Link to Item
    • Craciunescu, O, Raidy, T, Brizel, D, Blackwell, K, Vujaskovic, Z, Wong, T, Jones, E, Larrier, N, MacFall, J, and Dewhirst, M. "SU-FF-J-125: Therapy Assessment Using a Full Time Point (fTP) Pharmacokinetic Analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI): Role of Region of Interest (ROI) Selection in Three Tumor Sites." June 2006.  Full Text
    • Yin, F, Marks, L, Wang, Z, Kirkpatrick, J, Wu, J, Yoo, S, Larrier, N, Meyer, J, and Willett, C. "SU-FF-T-66: A Technique for Cone-Beam CT-Guided Stereotactic Body Radiation Therapy." June 2006.  Full Text

  • Journal Articles

    • Lee, AR, Grewal, DS, Cummings, TJ, Enyedi, LB, Larrier, NA, and Mruthyunjaya, P. "Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy." Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 21, no. 5 (October 2017): 410-412.  Full Text
    • Larrier, NA, Czito, BG, and Kirsch, DG. "Radiation Therapy for Soft Tissue Sarcoma: Indications and Controversies for Neoadjuvant Therapy, Adjuvant Therapy, Intraoperative Radiation Therapy, and Brachytherapy." Surgical oncology clinics of North America 25, no. 4 (October 2016): 841-860. (Review)  Full Text
    • Whitley, MJ, Cardona, DM, Lazarides, AL, Spasojevic, I, Ferrer, JM, Cahill, J, Lee, C-L, Snuderl, M, Blazer, DG, Hwang, ES, Greenup, RA, Mosca, PJ, Mito, JK, Cuneo, KC, Larrier, NA, O'Reilly, EK, Riedel, RF, Eward, WC, Strasfeld, DB, Fukumura, D, Jain, RK, Lee, WD, Griffith, LG, Bawendi, MG, Kirsch, DG, and Brigman, BE. "A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer." Science translational medicine 8, no. 320 (January 2016): 320ra4-.  Full Text
    • Larrier, N, and Larrier, N. "GenitourinaryGenitourinary (PublishedPublished)." (September 3, 2015): 283-296. (Chapter)  Full Text
    • Larrier, NA, Kirsch, DG, Riedel, RF, Levinson, H, Eward, WC, and Brigman, BE. "Practical radiation oncology for extremity sarcomas." Surg Oncol Clin N Am 22, no. 3 (July 2013): 433-443. (Review)  Full Text  Link to Item
    • Craciunescu, OI, Steffey, BA, Kelsey, CR, Larrier, NA, Paarz-Largay, CJ, Prosnitz, RG, Chao, N, Chute, J, Gasparetto, C, Horwitz, M, Long, G, Rizzieri, D, and Sullivan, KM. "Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial." Int J Radiat Oncol Biol Phys 79, no. 4 (March 15, 2011): 1248-1255.  Full Text  Link to Item
    • McMahon, RL, Larrier, NA, and Wu, QJ. "An image-guided technique for planning and verification of supine craniospinal irradiation. (Published online)" J Appl Clin Med Phys 12, no. 2 (January 31, 2011): 3310-.  Link to Item
    • McMahon, RL, Larrier, NA, and Wu, QJ. "An image-guided technique for planning and verification of supine craniospinal irradiation." Journal of Applied Clinical Medical Physics 12, no. 2 (2011): 184-190.
    • Nelson, JW, Yoo, DS, Sampson, JH, Isaacs, RE, Larrier, NA, Marks, LB, Yin, F-F, Wu, QJ, Wang, Z, and Kirkpatrick, JP. "Stereotactic body radiotherapy for lesions of the spine and paraspinal regions." Int J Radiat Oncol Biol Phys 73, no. 5 (April 1, 2009): 1369-1375.  Full Text  Link to Item
    • Riedel, RF, Larrier, N, Dodd, L, Kirsch, D, Martinez, S, and Brigman, BE. "The clinical management of chondrosarcoma." Curr Treat Options Oncol 10, no. 1-2 (April 2009): 94-106. (Review)  Full Text  Link to Item
    • Gururangan, S, Krauser, J, Watral, MA, Driscoll, T, Larrier, N, Reardon, DA, Rich, JN, Quinn, JA, Vredenburgh, JJ, Desjardins, A, McLendon, RE, Fuchs, H, Kurtzberg, J, and Friedman, HS. "Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma." Neuro Oncol 10, no. 5 (October 2008): 745-751.  Full Text  Link to Item
    • Miles, EF, Larrier, NA, Kelsey, CR, Hubbs, JL, Ma, J, Yoo, S, and Marks, LB. "Intensity-modulated radiotherapy for resected mesothelioma: the Duke experience." Int J Radiat Oncol Biol Phys 71, no. 4 (July 15, 2008): 1143-1150.  Full Text  Link to Item
    • Yin, F-F, Wang, Z, Yoo, S, Wu, QJ, Kirkpatrick, J, Larrier, N, Meyer, J, Willett, CG, and Marks, LB. "Integration of cone-beam CT in stereotactic body radiation therapy." Technol Cancer Res Treat 7, no. 2 (April 2008): 133-139.  Full Text  Link to Item
    • Wang, Z, Wu, QJ, Marks, LB, Larrier, N, and Yin, F-F. "Cone-beam CT localization of internal target volumes for stereotactic body radiotherapy of lung lesions." Int J Radiat Oncol Biol Phys 69, no. 5 (December 1, 2007): 1618-1624.  Full Text  Link to Item
    • Larrier, NA, and Marks, LB. "What radiation dose is safe in patients with non-small-cell lung cancer?." Nat Clin Pract Oncol 4, no. 2 (February 2007): 80-81.  Full Text  Link to Item
    • Mao, J, Kocak, Z, Zhou, S, Garst, J, Evans, ES, Zhang, J, Larrier, NA, Hollis, DR, Folz, RJ, and Marks, LB. "The Impact of Induction Chemotherapy and the Associated Tumor Response on Subsequent Radiation-Related Changes in Lung Function and Tumor Response." International Journal of Radiation Oncology Biology Physics 67, no. 5 (2007): 1360-1369.  Full Text
    • Anscher, MS, Garst, J, Marks, LB, Larrier, N, Dunphy, F, Herndon, JE, Clough, R, Marino, C, Vujaskovic, Z, Zhou, S, Dewhirst, MW, Shafman, TD, and Crawford, J. "Assessing the ability of the antiangiogenic and anticytokine agent thalidomide to modulate radiation-induced lung injury." Int J Radiat Oncol Biol Phys 66, no. 2 (October 1, 2006): 477-482.  Full Text  Link to Item
    • Mazur, MA, Gururangan, S, Bridge, JA, Cummings, TJ, Mukundan, S, Fuchs, H, Larrier, N, and Halperin, EC. "Intracranial Ewing sarcoma." Pediatr Blood Cancer 45, no. 6 (November 2005): 850-856.  Full Text  Link to Item
    • Rosoff, PM, Larrier, N, and Rice, HE. "Intra-abdominal desmoid tumor after successful treatment for Hodgkin disease." Pediatr Blood Cancer 45, no. 5 (October 15, 2005): 728-731.  Full Text  Link to Item
    • Anscher, MS, Chen, L, Rabbani, Z, Kang, S, Larrier, N, Huang, H, Samulski, TV, Dewhirst, MW, Brizel, DM, Folz, RJ, and Vujaskovic, Z. "Recent progress in defining mechanisms and potential targets for prevention of normal tissue injury after radiation therapy." Int J Radiat Oncol Biol Phys 62, no. 1 (May 1, 2005): 255-259.  Full Text  Link to Item
    • Chen, L, Brizel, DM, Rabbani, ZN, Samulski, TV, Farrell, CL, Larrier, N, Anscher, MS, and Vujaskovic, Z. "The protective effect of recombinant human keratinocyte growth factor on radiation-induced pulmonary toxicity in rats." Int J Radiat Oncol Biol Phys 60, no. 5 (December 1, 2004): 1520-1529.  Full Text  Link to Item
    • DeWeese, TL, Shipman, JM, Larrier, NA, Buckley, NM, Kidd, LR, Groopman, JD, Cutler, RG, te Riele, H, and Nelson, WG. "Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation." Proc Natl Acad Sci U S A 95, no. 20 (September 29, 1998): 11915-11920.  Link to Item
• Teaching & Mentoring
• 

  Recent Courses

  • RADONC 220C: BRIEF EXP. IN CLINICAL RADIATION/ONCOLOGY 2018
  • RADONC 415C: Clinical Radiation Oncology 2018

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