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Nicole Lewellyn Schramm-Sapyta

Associate Professor of the Practice in the Duke Institute for Brain Sciences
Duke Institute for Brain Sciences
308 Research Dr Room M055, Box 91003, Durham, NC 27708
308 Research Dr Room M055, Box 91003, Durham, NC 27708

Overview


Dr. Schramm-Sapyta earned her bachelor’s degree in Biochemistry from N.C. State University in 1994 and her doctoral degree in Pharmacology from Vanderbilt University in 2000.  She is currently an associate professor of the practice and Associate Director of the Duke Institute for Brain Sciences.  She has a long-standing interest in the neurobiology of drug addiction, using rodent models to investigate adolescent vulnerability to addiction. Her scientific expertise in this area supports her passion to bring scientific and clinical knowledge to inform public policy and educate the public about mental health and addiction.  Her course offerings at Duke include “Drugs and the Law,” “Reward and Addiction,” and “Biological Bases of Behavior.”  She co-leads a Bass Connections team on the subject of “Mental Health and the Justice System in Durham County.” 
 
Her early career was dedicated to exploring the biological basis of drug addiction using rodent behavioral models, with a particular interest in adolescent vulnerability to addiction. This work led her to appreciate the importance of resilience and mental health in individuals and society as a whole, and the role the public policy can play in this area. 

Current Appointments & Affiliations


Associate Professor of the Practice in the Duke Institute for Brain Sciences · 2020 - Present Duke Institute for Brain Sciences, University Institutes and Centers
Associate Director of the Duke Institute for Brain Sciences · 2019 - Present Duke Institute for Brain Sciences, University Institutes and Centers
Adjunct Assistant Professor in the Department of Psychiatry and Behavioral Sciences · 2021 - Present Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences
Associate of the Duke Initiative for Science & Society · 2021 - Present Duke Science & Society, University Initiatives & Academic Support Units

In the News


Published September 25, 2023
Finding Solutions Together
Published June 15, 2021
Addiction on the Brain with Dr. Nicole Schramm-Sapyta
Published May 15, 2018
New Opiate Policies can Help NC Prepare for Next Epidemic

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Recent Publications


Editorial: New insights on bringing social context into addiction neuroscience.

Journal Article Frontiers in behavioral neuroscience · January 2024 Full text Cite

Primary care need and engagement by people with criminal legal involvement: Descriptive and associational analysis using retrospective data on the entire population ever detained in one southeastern U.S. county jail 2014-2020.

Journal Article PLoS One · 2024 More than 7 million people are released each year from U.S. jails or prisons, many with chronic diseases that would benefit from primary care in their returning communities. The objective of this study was to provide an in-depth, payer-agnostic description ... Full text Link to item Cite

Reliance on Community Emergency Departments by People Ever Detained in Jail: Retrospective Cross-Sectional Study.

Journal Article J Correct Health Care · August 2023 Millions are confined in U.S. jails each year, often with unmet health and social needs. After release, many will visit the emergency department (ED). To illuminate their patterns of ED use, this study linked records from all individuals detained at a Sout ... Full text Link to item Cite
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Recent Grants


The Impact Neuroscience Program: an Inclusive Multi-Dimensional Program to Advance Career Training (R25)

Inst. Training Prgm or CMECollaborator · Awarded by National Institute of Mental Health · 2023 - 2028

Role of HPA Axis in Adolescent Vulnerability to Drug Addiction

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2011

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Education, Training & Certifications


Vanderbilt University · 2000 Ph.D.