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Nimmi Ramanujam

Robert W. Carr, Jr., Distinguished Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, 1427 Fciemas, Durham, NC 27708-0281
367 Gross Hall, 140 Science Drive, Durham, NC 27708

Overview


Nirmala (Nimmi) Ramanujam is the Robert W. Carr Professor of Biomedical Engineering, Professor of Cancer Pharmacology and Cancer Biology, and Global Health at Duke University.  She founded the Center for Global Women’s Health Technologies (GWHT) in 2013 to reshape women’s health through technology innovation. Her translation program in cervical and breast cancer has brought together multiple partners across U.S. and international academic institutions, hospitals, companies, non-governmental organizations, and ministries of health. 

Prof. Ramanujam creates technological solutions to detect cancer at its earliest stages, improve the effectiveness of current treatments and refine them to be more effective and less toxic. Prof. Ramanujam has developed point of care imaging technologies (Pocket colposcope and Callascope) and deep learning algorithms for the global prevention of cervical cancer.  She has implemented these technologies in global health care settings where access to cancer prevention and treatment is sparse or non-existent. Towards cancer treatment, Prof. Ramanujam has developed a drug releasing immunomodulating polymer that simultaneously disrupts tumor cells and elicits an immune boost. This injectable therapeutic can be deployed in settings where treatment is unavailable owing to its simple and low-cost formulation, and it can also provide an immune boost to checkpoint inhibitors. To understand why some tumors are resistant to therapy, she has created tools to image basic cellular processes that provide insight into tumor resistance. She has shown that metabolic plasticity in human residual disease can serve as a cue for treatment optimization and patient management.

Prof. Ramanujam has created a global consortium, Women Inspired strategies for health or WISH to establish technology-enabled community clinics for cervical cancer detection in Peru and Kenya. The MacArthur Foundation recognized WISH in 2019 as one of the top 100 most transformative and impactful global solutions.  She founded Calla Health in 2019 to commercialize women’s health technologies developed by her group. Through WISH and Calla Health, her femtech innovations have been disseminated in 11 countries and has reached more than 8,000 women globally. She has also co-developed the (In)visible Organ documentary on reshaping the future of women’s health through femtech. Her documentary was officially selected for the Women at the Center Film Festival at the International Papillomavirus Conference in 2020.  Prof. Ramanujam has seen the value of co-creating solutions with those that are at the level of the problem. This has led to the creation of a global education program IGNITE that intersects engineering design thinking, STEM concepts, and the U.N. Sustainable Development Goals. This peer mentoring model between undergraduate students and high school and middle students has been deployed in 5 locations globally, reaching more than 2,500 students and the online curriculum has more than 1000 users.

Prof. Ramanujam has received numerous awards, several of which are highlighted here. She received the prestigious DOD Breast Cancer Innovator award in 2024 given to gifted individuals who have a history of visionary scholarship, leadership, and creativity. She received the IEEE Biomedical Engineering Award Technical Field Award in 2023 given annually for outstanding contributions to the field of Biomedical engineering. She is a fellow of and has received several awards from professional societies in the field of biomedical optics.  She is a Fulbright scholar, a fellow of the National Academy of Inventors, and the American Institute of Biomedical and Biomedical Engineering (AIMBE). She has been invited as a speaker at the United Nations and at TEDx events. Her textbook, Biomedical Engineering for Global Health (2024), examines the intersection of health systems, point of care technologies, and data analytics / artificial intelligence and how these technological capabilities can broaden access to care in the 21st century.

Current Appointments & Affiliations


Robert W. Carr, Jr., Distinguished Professor of Biomedical Engineering · 2014 - Present Biomedical Engineering, Pratt School of Engineering
Professor of Biomedical Engineering · 2011 - Present Biomedical Engineering, Pratt School of Engineering
Research Professor of Global Health · 2012 - Present Duke Global Health Institute, University Institutes and Centers
Professor of Pharmacology and Cancer Biology · 2013 - Present Pharmacology & Cancer Biology, Basic Science Departments
Member of the Duke Cancer Institute · 2005 - Present Duke Cancer Institute, Institutes and Centers
Affiliate of the Duke Initiative for Science & Society · 2014 - Present Duke Science & Society, University Initiatives & Academic Support Units
Core Faculty Member, Duke-Margolis Institute for Health Policy · 2024 - Present Duke-Margolis Institute for Health Policy, University Initiatives & Academic Support Units

In the News


Published January 22, 2025
From Philosophy to the U.S. Court of Appeals, Duke Authors Cover Big Topics
Published December 2, 2024
Musician, Entrepreneur, educator - Nimmi Ramanujam has done it all
Published November 12, 2024
Pratt professor receives $10.4 million Defense Department grant for breast cancer research

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Recent Publications


Automated Image Clarity Detection for the Improvement of Colposcopy Imaging with Multiple Devices.

Journal Article Biomed Signal Process Control · February 2025 UNLABELLED: The proportion of women dying from cervical cancer in middle- and low-income countries is over 60%, twice that of their high-income counterparts. A primary screening strategy to eliminate this burden is cervix visualization and application of 3 ... Full text Link to item Cite

Development of Image Pre-processing Toolbox to Boost Cervical Cancer Detection

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2025 Globally, inequitable resources and access cause cervical cancer remain the fourth leading cause of death in women. Risk stratification with human papilloma virus (HPV) screening is fundamental in identifying vulnerable populations. Visual inspection with ... Full text Cite

Biomedical Engineering for Global Health Cancer, Inequity, and Technology

Book · July 31, 2024 Explore the fundamentals of biomedical engineering technologies with this thought-provoking introduction, framed around modern-day global cancer inequities. ... Cite
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Recent Grants


Duke Research Training Program in Surgical Oncology

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

A single shot therapy will accelerate the elimination of breast cancer

ResearchPrincipal Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2024 - 2028

The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program

ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028

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Education, Training & Certifications


University of Texas, Austin · 1995 Ph.D.
University of Texas, Austin · 1992 M.S.
University of Texas, Austin · 1989 B.S.