Nirmish Ramesh Shah
Assistant Professor of Medicine
Current Appointments & Affiliations
- Assistant Professor of Medicine, Medicine, Hematology, Medicine 2012
- Assistant Professor in Pediatrics, Pediatrics, Hematology-Oncology, Pediatrics 2012
Contact Information
- Department Of Medicine, Duke S, Durham, NC 27710
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nirmish.shah@duke.edu
(919) 668-5178
- Background
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Education, Training, & Certifications
- M.D., American University of the Caribbean 2000
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Duke Appointment History
- Medical Instructor in the Department of Medicine, Medicine, Hematology, Medicine 2010 - 2012
- Medical Instructor in the Department of Pediatrics, Pediatrics, Hematology-Oncology, Pediatrics 2010 - 2012
- Instructor Temporary in the Department of Medicine, Medicine, Hematology, Medicine 2010
- Expertise
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Subject Headings
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Global Scholarship
- Research
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Selected Grants
- Improving SCD Care using Web-based Guidelines, Nurse Care Managers and Peer Mentors in Primary Care and Emergency Departments in Central North Carolina awarded by National Institutes of Health 2016 - 2022
- A Double-blind, Randomized, Placebo-controlled, Multicenter Study of GBT440 Administered Orally to Subjects with Sickle Cell Disease awarded by Global Blood Therapeutics, Inc. 2017 - 2022
- Phase II study to assess SEG101 in Sickle Cell Patients awarded by Novartis Pharmaceuticals Corporation 2018 - 2022
- Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
- Open Label study to evaluate the safety and Pharmacokinetics of PF-06412528 in children 7-17 for treatment of moderate to severe pain awarded by Pfizer, Inc. 2018 - 2021
- Disseminating NIH Evidence Based Sickle Cell Recommendations in North Carolina awarded by Agency for Healthcare Research and Quality 2016 - 2020
- AZD9668 and Neutrophil Elastase Inhibition to Prevent Graft-versus-Host Disease awarded by National Institutes of Health 2018 - 2019
- Impact of Sickle-Trait on Transcriptional Regulation in P. Falciparum Parasites awarded by National Institutes of Health 2017 - 2019
- DU176b-A-U157/ A Phase 1, Open-Label, Single-Dose Non-Randomized Study To Evaluate Pharmacokinetics And Pharmacodynamics of Edoxaban In Pediatric Patients awarded by Daiichi Sankyo Inc 2015 - 2018
- EINSTEIN Junior Phase III: oral rivaroxaban in children with venous thrombosis awarded by Bayer Healthcare Pharmaceuticals Inc 2015 - 2018
- Use of Mobile Technology to Improve Acute Care Utilization in Sickle Cell Disease awarded by Agency for Healthcare Research and Quality 2015 - 2018
- Improving Pain in Sickle Cell Patients With Targeted Antithrombotic Therapy awarded by National Institutes of Health 2014 - 2017
- EPIC: Evaluation of purified poloxamer 188 in children in crisis awarded by : Mast Therapeutics, Inc. 2014 - 2017
- EVALUATION OF REPEAT ADMINISTRATION OF PURIFIED POLOXAMER 188 IN VASO-OCCLUSIVE CRISIS OF SICKLE CELL DISEASE (EPIC-E): AN OPEN-LABEL SAFETY EXTENSION TRIAL ASSESSING REPEAT ADMINISTRATION OF MST-188 awarded by : Mast Therapeutics, Inc. 2016 - 2017
- SUSTAIN awarded by Selexys Pharmaceuticals, Corp 2014 - 2017
- QuBBD: Collaborative Research: Advancing mHealth using Big Data Analytics: Statistical and Dynamical Systems Modeling of Real-Time Adaptive m-Intervention for Pain awarded by National Science Foundation 2015 - 2016
- Apixaban SC awarded by Bristol-Myers Squibb 2013 - 2016
- Use of Mobile Technology for Intensive Training in Medication Management awarded by Sickle Soft Incorporated 2014 - 2016
- Population-based Surveillance And Outcomes of Venous Thromboembolism awarded by Centers for Disease Control and Prevention 2012 - 2015
- Publications & Artistic Works
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Selected Publications
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Conference Papers
- Clifton, SM, Kang, C, Li, JJ, Long, Q, Shah, N, and Abrams, DM. "Hybrid Statistical and Mechanistic Mathematical Model Guides Mobile Health Intervention for Chronic Pain." July 2017. Full Text
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Journal Articles
- Klein, NP, Habanec, T, Kosina, P, Shah, NR, Kolhe, D, Miller, JM, Hezareh, M, and Van der Wielen, M. "Immunogenicity and safety of the quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in splenectomized or hyposplenic children and adolescents: Results of a phase III, open, non-randomized study." Vaccine (March 22, 2018). Full Text
- Leonard, S, Anderson, LM, Jonassaint, J, Jonassaint, C, and Shah, N. "Utilizing a Novel Mobile Health "Selfie" Application to Improve Compliance to Iron Chelation in Pediatric Patients Receiving Chronic Transfusions." Journal of pediatric hematology/oncology 39, no. 3 (April 2017): 223-229. Full Text
- Shah, NR. "Advances in iron chelation therapy: transitioning to a new oral formulation." Drugs in context 6 (January 2017): 212502-. Full Text
- Kayle, M, Tanabe, P, Shah, NR, Baker-Ward, L, and Docherty, SL. "Challenges in Shifting Management Responsibility From Parents to Adolescents With Sickle Cell Disease." Journal of pediatric nursing 31, no. 6 (November 2016): 678-690. Full Text
- Lunyera, J, Jonassaint, C, Jonassaint, J, and Shah, N. "Attitudes of Primary Care Physicians Toward Sickle Cell Disease Care, Guidelines, and Comanaging Hydroxyurea With a Specialist." Journal of primary care & community health (August 9, 2016). Full Text
- Wang, H-HS, Herbst, KW, Rothman, JA, Shah, NR, Wiener, JS, and Routh, JC. "Trends in Sickle Cell Disease-related Priapism in U.S. Children's Hospitals." Urology 89 (March 2016): 118-122. Full Text
- Goldenberg, NA, Abshire, T, Blatchford, PJ, Fenton, LZ, Halperin, JL, Hiatt, WR, Kessler, CM, Kittelson, JM, Manco-Johnson, MJ, Spyropoulos, AC, Steg, PG, Stence, NV, Turpie, AGG, Schulman, S, and Kids-DOTT Trial Investigators, . "Multicenter randomized controlled trial on Duration of Therapy for Thrombosis in Children and Young Adults (the Kids-DOTT trial): pilot/feasibility phase findings." Journal of thrombosis and haemostasis : JTH 13, no. 9 (September 2015): 1597-1605. Full Text
- Shah, N, Welsby, IJ, Fielder, MA, Jacobsen, WK, and Nielsen, VG. "Sickle cell disease is associated with iron mediated hypercoagulability." Journal of thrombosis and thrombolysis 40, no. 2 (August 2015): 182-185. Full Text
- Jonassaint, CR, Shah, N, Jonassaint, J, and De Castro, L. "Usability and Feasibility of an mHealth Intervention for Monitoring and Managing Pain Symptoms in Sickle Cell Disease: The Sickle Cell Disease Mobile Application to Record Symptoms via Technology (SMART)." Hemoglobin 39, no. 3 (January 2015): 162-168. Full Text
- Shah, N, Rollins, M, Landi, D, Shah, R, Bae, J, and De Castro, LM. "Differences in pain management between hematologists and hospitalists caring for patients with sickle cell disease hospitalized for vasoocclusive crisis." Clin J Pain 30, no. 3 (March 2014): 266-268. Full Text Link to Item
- Shah, N, Jonassaint, J, and De Castro, L. "Patients welcome the Sickle Cell Disease Mobile Application to Record Symptoms via Technology (SMART)." Hemoglobin 38, no. 2 (January 2014): 99-103. Full Text
- Shah, N, Rollins, M, Landi, D, Shah, R, Bae, J, and Castro, LMD. "Differences in pain management between hematologists and hospitalists caring for patients with sickle cell disease hospitalized for vasoocclusive crisis." Clinical Journal of Pain 30, no. 3 (2014): 266-268. Full Text
- Landi, D, Beckman, MG, Shah, NR, Bockenstedt, P, Grant, AM, Heit, JA, Key, NS, Kulkarni, R, Manco-Johnson, M, Moll, S, Philipp, CS, Andersen, JC, and Ortel, TL. "Characteristics of abdominal vein thrombosis in children and adults." Thromb Haemost 109, no. 4 (April 2013): 625-632. Full Text Link to Item
- Shah, N, Thornburg, C, Telen, MJ, and Ortel, TL. "Characterization of the hypercoagulable state in patients with sickle cell disease." Thromb Res 130, no. 5 (November 2012): e241-e245. Full Text Link to Item
- Verhovsek, M, Shah, NR, Wilcox, I, Koenig, SC, Barros, T, Thornburg, CD, Steinberg, MH, Luo, H-Y, and Chui, DHK. "Severe fetal and neonatal hemolytic anemia due to a 198 kb deletion removing the complete β-globin gene cluster." Pediatr Blood Cancer 59, no. 5 (November 2012): 941-944. Full Text Link to Item
- Shah, NR, Ortel, T, Thames, E, and James, AH. "Changes in Thrombin Generation During Pregnancy as Measured by Computerized Automated Thrombography (Cat)." AMERICAN JOURNAL OF HEMATOLOGY 87 (May 2012): S170-S170. Link to Item
- Shah, N, Landi, D, Shah, R, Rothman, J, De Castro, LM, and Thornburg, CD. "Complications of implantable venous access devices in patients with sickle cell disease." Am J Hematol 87, no. 2 (February 2012): 224-226. Full Text Link to Item
- Shah, NR, Landi, DB, Kreissman, SG, Kulbachi, E, and Moran, C. "Presentation and outcomes for children with bone marrow necrosis and acute lymphoblastic leukemia: a literature review." J Pediatr Hematol Oncol 33, no. 7 (October 2011): e316-e319. (Review) Full Text Link to Item
- Shah, NR, Telen, M, and Ortel, T. "Evaluation of thrombin generation in sickle cell patients and correlation to clinical disease." JOURNAL OF THROMBOSIS AND HAEMOSTASIS 9 (July 2011): 836-836. Link to Item
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- Scholarly, Clinical, & Service Activities
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Outreach & Engaged Scholarship
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