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Sarah Elise Nystrom

Assistant Professor of Medicine
Medicine, Nephrology

Current Appointments & Affiliations


Assistant Professor of Medicine · 2024 - Present Medicine, Nephrology, Medicine

Recent Publications


APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.

Journal Article J Clin Invest · January 16, 2024 Two coding variants of apolipoprotein L1 (APOL1), called G1 and G2, explain much of the excess risk of kidney disease in African Americans. While various cytotoxic phenotypes have been reported in experimental models, the proximal mechanism by which G1 and ... Full text Open Access Link to item Cite

JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids.

Journal Article JCI Insight · June 8, 2022 COVID-19 infection causes collapse of glomerular capillaries and loss of podocytes, culminating in a severe kidney disease called COVID-19-associated nephropathy (COVAN). The underlying mechanism of COVAN is unknown. We hypothesized that cytokines induced ... Full text Open Access Link to item Cite
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Recent Grants


Identification of Host-Specific Determinants of APOL1-associated COVAN

ResearchPrincipal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029

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Education, Training & Certifications


The Commonwealth Medical College · 2013 M.D.