Scholars@Duke

Academic Articles

• Ostrominski, John W., Sameer Hirji, Ankeet S. Bhatt, Javed Butler, Mona Fiuzat, Gregg C. Fonarow, Paul A. Heidenreich, et al. “Cost and Value in Contemporary Heart Failure Clinical Guidance Documents.” Jacc Heart Fail 10, no. 1 (January 2022): 1–11. https://doi.org/10.1016/j.jchf.2021.08.002.
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• Chouairi, Fouad, Michael A. Fuery, Clancy W. Mullan, Cesar Caraballo, Sounok Sen, Christopher Maulion, Samuel T. Wilkinson, et al. “The Impact of Depression on Outcomes in Patients With Heart Failure and Reduced Ejection Fraction Treated in the GUIDE-IT Trial.” Journal of Cardiac Failure 27, no. 12 (December 2021): 1359–66. https://doi.org/10.1016/j.cardfail.2021.06.008.
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• Costanzo, M. R., C. M. O’Connor, and H. O. Ventura. “Advanced Heart Failure: Progress and Disappointments.” Jacc: Heart Failure 9, no. 12 (December 1, 2021): 938–40. https://doi.org/10.1016/j.jchf.2021.10.005.
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• Wan, Luxi, Marc D. Samsky, Christopher M. O’Connor, Amanda Stebbins, Brooke Alhanti, Haider J. Warraich, Kimberly S. Johnson, et al. “Patterns of Change in Individual Domains of the Kansas City Cardiomyopathy Questionnaire With a Palliative Care Intervention for Patients With Advanced Heart Failure: Insights from PAL-HF.” J Card Fail 27, no. 12 (December 2021): 1476–78. https://doi.org/10.1016/j.cardfail.2021.02.007.
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• Ezekowitz, Justin A., Wendimagegn Alemayehu, Sarah Rathwell, Andrew D. Grant, Mona Fiuzat, David J. Whellan, Tariq Ahmad, et al. “The influence of comorbidities on achieving an N-terminal pro-b-type natriuretic peptide target: a secondary analysis of the GUIDE-IT trial.” Esc Heart Failure, November 16, 2021. https://doi.org/10.1002/ehf2.13692.
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• Ezekowitz, Justin A., Yinggan Zheng, Alain Cohen-Solal, Vojtěch Melenovský, Jorge Escobedo, Javed Butler, Adrian F. Hernandez, et al. “Hemoglobin and Clinical Outcomes in the Vericiguat Global Study in Patients With Heart Failure and Reduced Ejection Fraction (VICTORIA).” Circulation 144, no. 18 (November 2021): 1489–99. https://doi.org/10.1161/circulationaha.121.056797.
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• Luo, Nancy, Christopher M. O’Connor, Karen Chiswell, Kevin J. Anstrom, L Kristin Newby, and Robert J. Mentz. “Survival in Patients With Nonischemic Cardiomyopathy With Preserved vs Reduced Ejection Fraction.” Cjc Open 3, no. 11 (November 2021): 1333–40. https://doi.org/10.1016/j.cjco.2021.06.007.
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• Zeitler, E. P., C. M. O’Connor, W. Abraham, and J. A. Lindenfeld. “How Is Medical Device Innovation Currently Supported in the U.S.?: From the Heart Failure Collaboratory.” Jacc: Heart Failure 9, no. 11 (November 1, 2021): 855–57. https://doi.org/10.1016/j.jchf.2021.09.005.
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• Granger, Bradi B., James A. Tulsky, Brystana G. Kaufman, Robert M. Clare, Kevin Anstrom, Daniel B. Mark, Kimberly A. Johnson, et al. “Polypharmacy in Palliative Care for Advanced Heart Failure: The PAL-HF Experience.” Journal of Cardiac Failure, October 7, 2021. https://doi.org/10.1016/j.cardfail.2021.08.021.
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• Greenberg, B., C. M. O’Connor, and G. M. Felker. “Classifying Heart Failure in the 21st Century: Matching Taxonomy With Science.” Jacc: Heart Failure 9, no. 10 (October 1, 2021): 771–73. https://doi.org/10.1016/j.jchf.2021.08.004.
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• Mentz, Robert J., David J. Whellan, Gordon R. Reeves, Amy M. Pastva, Pamela Duncan, Bharathi Upadhya, M Benjamin Nelson, et al. “Rehabilitation Intervention in Older Patients With Acute Heart Failure With Preserved Versus Reduced Ejection Fraction.” Jacc. Heart Failure 9, no. 10 (October 2021): 747–57. https://doi.org/10.1016/j.jchf.2021.05.007.
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• Anchouche, Khalil, Malik Elharram, Emily Oulousian, Amir Razaghizad, Robert Avram, Guillaume Marquis-Gravel, Varinder Kaur Randhawa, et al. “Use of Actigraphy (Wearable Digital Sensors to Monitor Activity) in Heart Failure Randomized Clinical Trials: A Scoping Review.” Can J Cardiol 37, no. 9 (September 2021): 1438–49. https://doi.org/10.1016/j.cjca.2021.07.001.
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• Ezekowitz, Justin, Robert J. Mentz, Cynthia M. Westerhout, Nancy K. Sweitzer, Michael M. Givertz, Ileana L. Piña, Christopher M. O’Connor, et al. “Participation in a Heart Failure Clinical Trial: Perspectives and Opportunities From the VICTORIA Trial and VICTORIA Simultaneous Registry.” Circ Heart Fail 14, no. 9 (September 2021): e008242. https://doi.org/10.1161/CIRCHEARTFAILURE.120.008242.
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• Fudim, Marat, Toi Spates, Jie-Lena Sun, Veraprapas Kittipibul, Jeffrey M. Testani, Randall C. Starling, WH Wilson Tang, et al. “Early diuretic strategies and the association with In-hospital and Post-discharge outcomes in acute heart failure.” American Heart Journal 239 (September 2021): 110–19. https://doi.org/10.1016/j.ahj.2021.05.011.
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• Ibrahim, Nasrien E., Christopher M. O’Connor, and James L. Januzzi. “From Clinical Trials to Communities: The 5 C's of Ensuring Equitable Delivery of Heart Failure Therapies.” Jacc. Heart Failure 9, no. 9 (September 2021): 694–96. https://doi.org/10.1016/j.jchf.2021.08.001.
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• Rosner, Carolyn M., Leonard Genovese, Behnam N. Tehrani, Melany Atkins, Hooman Bakhshi, Saquib Chaudhri, Abdulla A. Damluji, et al. “Myocarditis Temporally Associated With COVID-19 Vaccination.” Circulation 144, no. 6 (August 10, 2021): 502–5. https://doi.org/10.1161/CIRCULATIONAHA.121.055891.
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• Ponikowski, Piotr, Wendimagegn Alemayehu, Ali Oto, M Cecilia Bahit, Ebrahim Noori, Mahesh J. Patel, Javed Butler, et al. “Vericiguat in patients with atrial fibrillation and heart failure with reduced ejection fraction: insights from the VICTORIA trial.” Eur J Heart Fail 23, no. 8 (August 2021): 1300–1312. https://doi.org/10.1002/ejhf.2285.
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• Psotka, Mitchell A., Christopher M. O’Connor, and John R. Teerlink. “Empower the Future… Even Oprah Had a Mentor!.” Jacc Heart Fail 9, no. 8 (August 2021): 604–5. https://doi.org/10.1016/j.jchf.2021.06.006.
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• Voors, Adriaan A., Hillary Mulder, Eugene Reyes, Martin R. Cowie, Johan Lassus, Adrian F. Hernandez, Justin A. Ezekowitz, et al. “Renal function and the effects of vericiguat in patients with worsening heart failure with reduced ejection fraction: insights from the VICTORIA (Vericiguat Global Study in Subjects with HFrEF) trial.” Eur J Heart Fail 23, no. 8 (August 2021): 1313–21. https://doi.org/10.1002/ejhf.2221.
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• Kitzman, Dalane W., David J. Whellan, Pamela Duncan, Amy M. Pastva, Robert J. Mentz, Gordon R. Reeves, M Benjamin Nelson, et al. “Physical Rehabilitation for Older Patients Hospitalized for Heart Failure.” N Engl J Med 385, no. 3 (July 15, 2021): 203–16. https://doi.org/10.1056/NEJMoa2026141.
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• Lang, Ninian N., Faheem A. Ahmad, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jorg Taubel, et al. “Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial.” Eur J Heart Fail 23, no. 7 (July 2021): 1147–55. https://doi.org/10.1002/ejhf.2138.
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• Ahmad, Tariq, and Christopher O’Connor. “Change Is the Only Constant in Heart Failure.” Jacc. Heart Failure 9, no. 7 (July 2021): 528–29. https://doi.org/10.1016/j.jchf.2021.06.001.
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• Fuery, Michael A., Fouad Chouairi, James L. Januzzi, Gordon W. Moe, Cesar Caraballo, Megan McCullough, P Elliott Miller, et al. “Intercountry Differences in Guideline-Directed Medical Therapy and Outcomes Among Patients With Heart Failure.” Jacc Heart Fail 9, no. 7 (July 2021): 497–505. https://doi.org/10.1016/j.jchf.2021.02.011.
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• Markousis-Mavrogenis, George, Jasper Tromp, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “The Additive Prognostic Value of Serial Plasma Interleukin-6 Levels over Changes in Brain Natriuretic Peptide in Patients with Acute Heart Failure.” Journal of Cardiac Failure 27, no. 7 (July 2021): 808–11. https://doi.org/10.1016/j.cardfail.2021.01.008.
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• Whellan, David J., and Christopher M. O’Connor. “Function Follows Form.” Jacc. Heart Failure 9, no. 7 (July 2021): 482–83. https://doi.org/10.1016/j.jchf.2021.02.012.
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• Mentz, Robert J., Hillary Mulder, Arend Mosterd, Nancy K. Sweitzer, Michele Senni, Javed Butler, Justin A. Ezekowitz, et al. “Clinical Outcome Predictions for the VerICiguaT Global Study in Subjects With Heart Failure With Reduced Ejection Fraction (VICTORIA) Trial.” J Card Fail, June 24, 2021. https://doi.org/10.1016/j.cardfail.2021.05.016.
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• Batchelor, Wayne B., Abdulla A. Damluji, Celina Yong, Mona Fiuzat, Scott D. Barnett, David E. Kandzari, Matthew W. Sherwood, et al. “Does study subject diversity influence cardiology research site performance?: Insights from 2 U.S. National Coronary Stent Registries.” Am Heart J 236 (June 2021): 37–48. https://doi.org/10.1016/j.ahj.2021.02.003.
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• Kaufman, Brystana G., Bradi B. Granger, Jie-Lena Sun, Gillian Sanders, Donald H. Taylor, Daniel B. Mark, Haider Warraich, et al. “The Cost-Effectiveness of Palliative Care: Insights from the PAL-HF Trial.” Journal of Cardiac Failure 27, no. 6 (June 2021): 662–69. https://doi.org/10.1016/j.cardfail.2021.02.019.
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• Lam, Carolyn S. P., Anna Giczewska, Karen Sliwa, Frank Edelmann, Jens Refsgaard, Edimar Bocchi, Justin A. Ezekowitz, et al. “Clinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights From the VICTORIA Trial.” Jama Cardiol 6, no. 6 (June 1, 2021): 706–12. https://doi.org/10.1001/jamacardio.2020.6455.
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• O’Connor, Christopher M., Joseph Rogers, and JoAnn Lindenfeld. “Device Development in the Gray Zone: One Step Forward.” Jacc Heart Fail 9, no. 6 (June 2021): 463–64. https://doi.org/10.1016/j.jchf.2021.05.001.
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• Perez, Antonio L., Justin L. Grodin, Thanat Chaikijurajai, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, et al. “Interleukin-6 and Outcomes in Acute Heart Failure: An ASCEND-HF Substudy.” J Card Fail 27, no. 6 (June 2021): 670–76. https://doi.org/10.1016/j.cardfail.2021.01.006.
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• Tehrani, Behnam N., Abdulla A. Damluji, Matthew W. Sherwood, Carolyn Rosner, Alexander G. Truesdell, Kelly C. Epps, Edward Howard, et al. “Transradial access in acute myocardial infarction complicated by cardiogenic shock: Stratified analysis by shock severity.” Catheter Cardiovasc Interv 97, no. 7 (June 1, 2021): 1354–66. https://doi.org/10.1002/ccd.29098.
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• Blumer, Vanessa, Stephen J. Greene, Angie Wu, Javed Butler, Justin A. Ezekowitz, JoAnn Lindenfeld, Brooke Alhanti, Adrian F. Hernandez, Christopher M. O’Connor, and Robert J. Mentz. “Sex Differences in Clinical Course and Patient-Reported Outcomes Among Patients Hospitalized for Heart Failure.” Jacc Heart Fail 9, no. 5 (May 2021): 336–45. https://doi.org/10.1016/j.jchf.2020.12.011.
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• Lindenfeld, JoAnn, Mona Fiuzat, and Christopher O’Connor. “Promoting Diversity in Clinical Trial Leadership: A Call to Action.” Jacc Heart Fail 9, no. 5 (May 2021): 401–2. https://doi.org/10.1016/j.jchf.2021.03.005.
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• Bhatt, Ankeet S., Mona Fiuzat, JoAnn Lindenfeld, Christopher M. O’Connor, and Javed Butler. “Reply: Improving Heart Failure Therapeutics: Thinking Outside the Pillbox?” Jacc Heart Fail 9, no. 4 (April 2021): 320–21. https://doi.org/10.1016/j.jchf.2021.01.005.
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• Blumer, Vanessa, Robert J. Mentz, Jie-Lena Sun, Javed Butler, Marco Metra, Adriaan A. Voors, Adrian F. Hernandez, Christopher M. O’Connor, and Stephen J. Greene. “Prognostic Role of Prior Heart Failure Hospitalization Among Patients Hospitalized for Worsening Chronic Heart Failure.” Circulation. Heart Failure 14, no. 4 (April 2021): e007871. https://doi.org/10.1161/circheartfailure.120.007871.
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• O’Connor, Christopher M. “Heart Failure Leadership, Culture, and Governance: Lessons Learned From Tom Brady.” Jacc Heart Fail 9, no. 4 (April 2021): 317–18. https://doi.org/10.1016/j.jchf.2021.02.002.
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• Yang, Siyun, Monique Anderson Starks, Adrian F. Hernandez, Elizabeth L. Turner, Robert M. Califf, Christopher M. O’Connor, Robert J. Mentz, and Kingshuk Roy Choudhury. “Corrigendum to "Impact of baseline covariate imbalance on bias in treatment effect estimation in cluster randomized trials: Race as an example" [Contemporary Clinical Trials volume 88 (2020) 105775].” Contemporary Clinical Trials 103 (April 2021): 106298. https://doi.org/10.1016/j.cct.2021.106298.
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• Brooksbank, Jeremy A., Stephen J. Greene, Hailey M. Harris, Amanda Stebbins, Mona Fiuzat, David J. Whellan, Brooke Alhanti, et al. “Beta-blocker and ACE-inhibitor dosing as a function of body surface area: From the HF-ACTION trial.” American Heart Journal 233 (March 2021): 1–4. https://doi.org/10.1016/j.ahj.2020.11.003.
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• Fudim, Marat, Joseph B. Lerman, Courtney Page, Brooke Alhanti, Robert M. Califf, Justin A. Ezekowitz, Nicolas Girerd, et al. “Plasma Volume Status and Its Association With In-Hospital and Postdischarge Outcomes in Decompensated Heart Failure.” Journal of Cardiac Failure 27, no. 3 (March 2021): 297–308. https://doi.org/10.1016/j.cardfail.2020.09.478.
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• O’Connor, Christopher M. “Reviewers Hall of Fame: 2020 Top Reviewers.” Jacc Heart Fail 9, no. 3 (March 2021): 241. https://doi.org/10.1016/j.jchf.2021.01.004.
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• Felker, G Michael, John J. V. McMurray, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jan Belohlavek, et al. “Effects of a Novel Nitroxyl Donor in Acute Heart Failure: The STAND-UP AHF Study.” Jacc Heart Fail 9, no. 2 (February 2021): 146–57. https://doi.org/10.1016/j.jchf.2020.10.012.
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• O’Connor, Christopher M. “Meet Me in the Middle: Lessons From the Cardiorenal Advisory Committee for Sacubitril/Valsartan in HFpEF.” Jacc Heart Fail 9, no. 2 (February 2021): 161–63. https://doi.org/10.1016/j.jchf.2020.12.003.
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• Farsky, Pedro S., Jennifer White, Hussein R. Al-Khalidi, Carla A. Sueta, Jean L. Rouleau, Julio A. Panza, Eric J. Velazquez, Christopher M. O’Connor, and Christopher M. Working Group and Surgical Treatment for IsChemic Heart failure Trial Investigators. “Optimal medical therapy with or without surgical revascularization and long-term outcomes in ischemic cardiomyopathy.” J Thorac Cardiovasc Surg, January 7, 2021. https://doi.org/10.1016/j.jtcvs.2020.12.094.
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• Bhatt, Ankeet S., William T. Abraham, JoAnn Lindenfeld, Michael Bristow, Peter E. Carson, G Michael Felker, Gregg C. Fonarow, et al. “Treatment of HF in an Era of Multiple Therapies: Statement From the HF Collaboratory.” Jacc Heart Fail 9, no. 1 (January 2021): 1–12. https://doi.org/10.1016/j.jchf.2020.10.014.
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• O’Connor, Christopher M. “A Generation Passed; A Generation Forward: Why Joseph C. Greenfield, Chairman of Medicine, Duke University, Matters Today (1931 to 2020).” Jacc Heart Fail 9, no. 1 (January 2021): 80–81. https://doi.org/10.1016/j.jchf.2020.11.005.
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• Abraham, William T., Mitchell A. Psotka, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Roxana Mehran, Amrut V. Ambardekar, et al. “Standardized definitions for evaluation of heart failure therapies: scientific expert panel from the Heart Failure Collaboratory and Academic Research Consortium.” Eur J Heart Fail 22, no. 12 (December 2020): 2175–86. https://doi.org/10.1002/ejhf.2018.
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• Sbolli, Marco, and Christopher M. O’Connor. “Aldosterone: Behind the Scenes of Depression and Heart Failure?” Jacc Heart Fail 8, no. 12 (December 2020): 1021–23. https://doi.org/10.1016/j.jchf.2020.10.006.
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• Angraal, Suveen, César Caraballo, Peter Kahn, Ambika Bhatnagar, Bikramjot Singh, F Perry Wilson, Mona Fiuzat, et al. “Geographical affiliation with top 10 NIH-funded academic medical centers and differences between mortality from cardiovascular disease and cancer.” Am Heart J 230 (December 2020): 54–58. https://doi.org/10.1016/j.ahj.2020.08.014.
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• Lanfear, David E., Jasmine A. Luzum, Ruicong She, Hongsheng Gui, Mark P. Donahue, Christopher M. O’Connor, Kirkwood F. Adams, et al. “Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure.” Circ Heart Fail 13, no. 12 (December 2020): e007012. https://doi.org/10.1161/CIRCHEARTFAILURE.119.007012.
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• O’Connor, Christopher M., and Michael R. Bristow. “Changing U.S. Heart Failure Research Culture: Part 2-Recognizing Frontline Investigators and Coordinators.” Jacc Heart Fail 8, no. 12 (December 2020): 1050–51. https://doi.org/10.1016/j.jchf.2020.10.010.
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• Perego, Carlotta, Marco Sbolli, Claudia Specchia, Mona Fiuzat, Zachary R. McCaw, Marco Metra, Chiara Oriecuia, et al. “Utility of Restricted Mean Survival Time Analysis for Heart Failure Clinical Trial Evaluation and Interpretation.” Jacc Heart Fail 8, no. 12 (December 2020): 973–83. https://doi.org/10.1016/j.jchf.2020.07.005.
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• Psotka, Mitchell A., William T. Abraham, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Tariq Ahmad, Ankeet S. Bhatt, et al. “Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.” J Am Coll Cardiol 76, no. 20 (November 17, 2020): 2368–78. https://doi.org/10.1016/j.jacc.2020.09.544.
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• O’Connor, Christopher M. “Personalized Therapeutic Approach: Gun Control for Shotgun Therapy.” Jacc Heart Fail 8, no. 11 (November 2020): 954–55. https://doi.org/10.1016/j.jchf.2020.09.002.
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• Sbolli, Marco, Mona Fiuzat, Dario Cani, and Christopher M. O’Connor. “Depression and heart failure: the lonely comorbidity.” Eur J Heart Fail 22, no. 11 (November 2020): 2007–17. https://doi.org/10.1002/ejhf.1865.
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• Ezekowitz, Justin A., Christopher M. O’Connor, Richard W. Troughton, Wendimagegn G. Alemayehu, Cynthia M. Westerhout, Adriaan A. Voors, Javed Butler, et al. “N-Terminal Pro-B-Type Natriuretic Peptide and Clinical Outcomes: Vericiguat Heart Failure With Reduced Ejection Fraction Study.” Jacc Heart Fail 8, no. 11 (November 2020): 931–39. https://doi.org/10.1016/j.jchf.2020.08.008.
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• Armstrong, Paul W., Carolyn S. P. Lam, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Burkert Pieske, et al. “Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial.” Jama 324, no. 15 (October 20, 2020): 1512–21. https://doi.org/10.1001/jama.2020.15922.
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• Armstrong, Paul W., Kevin J. Anstrom, Christopher M. O’Connor, and Christopher M. VICTORIA Study Group. “Vericiguat in Heart Failure with Reduced Ejection Fraction. Reply.” N Engl J Med 383, no. 15 (October 8, 2020): 1497–98. https://doi.org/10.1056/NEJMc2027731.
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• Psotka, Mitchell A., Mona Fiuzat, Marco Metra, and Christopher M. O’Connor. “Reply: Potential Mechanisms to Improve Heart Failure Clinical Trial Publication Rates.” J Am Coll Cardiol 76, no. 14 (October 6, 2020): 1717–18. https://doi.org/10.1016/j.jacc.2020.08.013.
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• Armstrong, Paul W., Burkert Pieske, and Christopher M. O’Connor. “Effects of vericiguat in heart failure with reduced ejection fraction: do not forget sST2. Reply.” Eur J Heart Fail 22, no. 10 (October 2020): 1935. https://doi.org/10.1002/ejhf.1765.
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• O’Connor, Christopher M. “Convalescence From COVID Research: Lessons From the Heart Failure Community.” Jacc Heart Fail 8, no. 10 (October 2020): 870–71. https://doi.org/10.1016/j.jchf.2020.08.005.
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• O’Connor, Christopher M., and Cleveland Francis. “The Journey of an American Black Cardiologist.” Jacc Heart Fail 8, no. 9 (September 2020): 780–81. https://doi.org/10.1016/j.jchf.2020.08.001.
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• Psotka, Mitchell A., Mona Fiuzat, Scott D. Solomon, Cynthia Chauhan, G Michael Felker, Javed Butler, John R. Teerlink, Shashank S. Sinha, Christopher M. O’Connor, and Marvin A. Konstam. “Challenges and Potential Improvements to Patient Access to Pharmaceuticals: Examples From Cardiology.” Circulation 142, no. 8 (August 25, 2020): 790–98. https://doi.org/10.1161/CIRCULATIONAHA.119.044976.
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• Abraham, William T., Mona Fiuzat, Mitchell A. Psotka, and Christopher M. O’Connor. “Heart Failure Collaboratory Statement on Remote Monitoring and Social Distancing in the Landscape of COVID-19.” Jacc Heart Fail 8, no. 8 (August 2020): 692–94. https://doi.org/10.1016/j.jchf.2020.06.006.
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• Damluji, Abdulla A., Michael Fabbro, Richard H. Epstein, Stefan Rayer, Ying Wang, Mauro Moscucci, Mauricio G. Cohen, et al. “Transcatheter Aortic Valve Replacement in Low-Population Density Areas: Assessing Healthcare Access for Older Adults With Severe Aortic Stenosis.” Circ Cardiovasc Qual Outcomes 13, no. 8 (August 2020): e006245. https://doi.org/10.1161/CIRCOUTCOMES.119.006245.
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• Reza, Nosheen, Ayman Samman Tahhan, Nadim Mahmud, Ersilia M. DeFilippis, Alaaeddin Alrohaibani, Muthiah Vaduganathan, Stephen J. Greene, et al. “Representation of Women Authors in International Heart Failure Guidelines and Contemporary Clinical Trials.” Circ Heart Fail 13, no. 8 (August 2020): e006605. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006605.
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• Fiuzat, Mona, Justin Ezekowitz, Wendimagegn Alemayehu, Cynthia M. Westerhout, Marco Sbolli, Dario Cani, David J. Whellan, et al. “Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial.” Jama Cardiol 5, no. 7 (July 1, 2020): 757–64. https://doi.org/10.1001/jamacardio.2020.0640.
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• O’Connor, Christopher M. “COVID-19 Fatigue: Not So Fast.” Jacc Heart Fail 8, no. 7 (July 2020): 592–94. https://doi.org/10.1016/j.jchf.2020.06.001.
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• Psotka, Mitchell A., Federica Latta, Dario Cani, Mona Fiuzat, Marco Sbolli, Scott Barnett, Marco Metra, and Christopher M. O’Connor. “Publication Rates of Heart Failure Clinical Trials Remain Low.” J Am Coll Cardiol 75, no. 25 (June 30, 2020): 3151–61. https://doi.org/10.1016/j.jacc.2020.04.068.
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• O’Connor, Christopher M. “Heart Failure Editorial Emergencies in the COVID-19 Era.” Jacc Heart Fail 8, no. 6 (June 2020): 518. https://doi.org/10.1016/j.jchf.2020.04.002.
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• Bhatt, Ankeet S., Andrew P. Ambrosy, Allison Dunning, Adam D. DeVore, Javed Butler, Shelby Reed, Adriaan Voors, et al. “The burden of non-cardiac comorbidities and association with clinical outcomes in an acute heart failure trial - insights from ASCEND-HF.” Eur J Heart Fail 22, no. 6 (June 2020): 1022–31. https://doi.org/10.1002/ejhf.1795.
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• Damluji, Abdulla A., Gregory Rodriguez, Thomas Noel, Lakerria Davis, Vishal Dahya, Behnam Tehrani, Kelly Epps, et al. “Sarcopenia and health-related quality of life in older adults after transcatheter aortic valve replacement.” Am Heart J 224 (June 2020): 171–81. https://doi.org/10.1016/j.ahj.2020.03.021.
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• Fiuzat, Mona, Naomi Lowy, Norman Stockbridge, Marco Sbolli, Federica Latta, JoAnn Lindenfeld, Eldrin F. Lewis, et al. “Endpoints in Heart Failure Drug Development: History and Future.” Jacc. Heart Failure 8, no. 6 (June 2020): 429–40. https://doi.org/10.1016/j.jchf.2019.12.011.
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• Armstrong, Paul W., Burkert Pieske, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Javed Butler, Carolyn S. P. Lam, et al. “Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.” N Engl J Med 382, no. 20 (May 14, 2020): 1883–93. https://doi.org/10.1056/NEJMoa1915928.
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• Reddy, Yogesh N. V., Barry A. Borlaug, Christopher M. O’Connor, and Bernard J. Gersh. “Novel approaches to the management of chronic systolic heart failure: future directions and unanswered questions.” Eur Heart J 41, no. 18 (May 7, 2020): 1764–74. https://doi.org/10.1093/eurheartj/ehz364.
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• Abraham, William T., Mona Fiuzat, Mitchell A. Psotka, and Christopher M. O’Connor. “Heart Failure Collaboratory Statement on Clinical Trials in the Landscape of COVID-19.” Jacc Heart Fail 8, no. 5 (May 2020): 423–25. https://doi.org/10.1016/j.jchf.2020.03.005.
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• Cooper, Lauren B., Mitchell A. Psotka, Shashank Sinha, Brahmajee K. Nallamothu, Christopher R. deFilippi, Wayne Batchelor, Christopher M. O’Connor, and Abdulla A. Damluji. “Specificity of administrative coding for older adults with acute heart failure hospitalizations.” Am Heart J 223 (May 2020): 1–2. https://doi.org/10.1016/j.ahj.2020.02.004.
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• Butler, Javed, Muhammad Shahzeb Khan, Stefan D. Anker, Gregg C. Fonarow, Raymond J. Kim, Savina Nodari, Christopher M. O’Connor, et al. “Effects of Elamipretide on Left Ventricular Function in Patients With Heart Failure With Reduced Ejection Fraction: The PROGRESS-HF Phase 2 Trial.” J Card Fail 26, no. 5 (May 2020): 429–37. https://doi.org/10.1016/j.cardfail.2020.02.001.
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• Ibrahim, Nasrien E., John C. Burnett, Javed Butler, Alexander Camacho, G Michael Felker, Mona Fiuzat, Christopher O’Connor, et al. “Natriuretic Peptides as Inclusion Criteria in Clinical Trials: A JACC: Heart Failure Position Paper.” Jacc. Heart Failure 8, no. 5 (May 2020): 347–58. https://doi.org/10.1016/j.jchf.2019.12.010.
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• Pandhi, Paloma, Jozine M. Ter Maaten, Johanna E. Emmens, Joachim Struck, Andreas Bergmann, John G. Cleland, Michael M. Givertz, et al. “Clinical value of pre-discharge bio-adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission.” Eur J Heart Fail 22, no. 4 (April 2020): 683–91. https://doi.org/10.1002/ejhf.1693.
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• O’Connor, Christopher M. “Heart Failure Multidisciplinary Teams and New Zealand Rugby: What Can We Learn From the "All Blacks" Rugby Team?” Jacc. Heart Failure 8, no. 4 (April 2020): 341–42. https://doi.org/10.1016/j.jchf.2020.02.003.
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• Truby, Lauren K., Christopher O’Connor, Mona Fiuzat, Amanda Stebbins, Adrian Coles, Chetan B. Patel, Bradi Granger, et al. “Sex Differences in Quality of Life and Clinical Outcomes in Patients With Advanced Heart Failure: Insights From the PAL-HF Trial.” Circ Heart Fail 13, no. 4 (April 2020): e006134. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006134.
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• O’Connor, Christopher M. “The Heart Failure High Five: Medical Therapy and Policy: 2019.” Jacc Heart Fail 8, no. 1 (January 2020): 81–82. https://doi.org/10.1016/j.jchf.2019.11.008.
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• Psotka, Mitchell A., Gregg C. Fonarow, Larry A. Allen, Karen E. Joynt Maddox, Mona Fiuzat, Paul Heidenreich, Adrian F. Hernandez, Marvin A. Konstam, Clyde W. Yancy, and Christopher M. O’Connor. “The Hospital Readmissions Reduction Program: Nationwide Perspectives and Recommendations: A JACC: Heart Failure Position Paper.” Jacc Heart Fail 8, no. 1 (January 2020): 1–11. https://doi.org/10.1016/j.jchf.2019.07.012.
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• Yang, Siyun, Monique Anderson Starks, Adrian F. Hernandez, Elizabeth L. Turner, Robert M. Califf, Christopher M. O’Connor, Robert J. Mentz, and Kingshuk Roy Choudhury. “Impact of baseline covariate imbalance on bias in treatment effect estimation in cluster randomized trials: Race as an example.” Contemporary Clinical Trials 88 (January 2020): 105775. https://doi.org/10.1016/j.cct.2019.04.016.
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• Butler, Javed, Milton Packer, Stephen J. Greene, Mona Fiuzat, Stefan D. Anker, Kevin J. Anstrom, Peter E. Carson, et al. “Heart Failure End Points in Cardiovascular Outcome Trials of Sodium Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Critical Evaluation of Clinical and Regulatory Issues.” Circulation 140, no. 25 (December 16, 2019): 2108–18. https://doi.org/10.1161/circulationaha.119.042155.
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• Caraballo, César, Nihar R. Desai, Hillary Mulder, Brooke Alhanti, F Perry Wilson, Mona Fiuzat, G Michael Felker, et al. “Clinical Implications of the New York Heart Association Classification.” J Am Heart Assoc 8, no. 23 (December 3, 2019): e014240. https://doi.org/10.1161/JAHA.119.014240.
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• DeVore, Adam D., Eric Yow, Mitchell W. Krucoff, Matthew W. Sherwood, Linda K. Shaw, Karen Chiswell, Christopher M. O’Connor, Erik Magnus Ohman, and Eric J. Velazquez. “Percutaneous coronary intervention outcomes in patients with stable coronary disease and left ventricular systolic dysfunction.” Esc Heart Fail 6, no. 6 (December 2019): 1233–42. https://doi.org/10.1002/ehf2.12510.
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• O’Connor, Christopher M. “N-1 and Sequencing Clinical Heart Failure Trials: Charting the Path for Future Clinical Care.” Jacc Heart Fail 7, no. 12 (December 2019): 1089–90. https://doi.org/10.1016/j.jchf.2019.10.006.
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• Pieske, Burkert, Mahesh J. Patel, Cynthia M. Westerhout, Kevin J. Anstrom, Javed Butler, Justin Ezekowitz, Adrian F. Hernandez, et al. “Baseline features of the VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction) trial.” Eur J Heart Fail 21, no. 12 (December 2019): 1596–1604. https://doi.org/10.1002/ejhf.1664.
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• Regan, Jessica A., Dalane W. Kitzman, Eric S. Leifer, William E. Kraus, Jerome L. Fleg, Daniel E. Forman, David J. Whellan, et al. “Impact of Age on Comorbidities and Outcomes in Heart Failure With Reduced Ejection Fraction.” Jacc. Heart Failure 7, no. 12 (December 2019): 1056–65. https://doi.org/10.1016/j.jchf.2019.09.004.
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• Beldhuis, Iris E., Koen W. Streng, Peter van der Meer, Jozine M. Ter Maaten, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, et al. “Trajectories of Changes in Renal Function in Patients with Acute Heart Failure.” J Card Fail 25, no. 11 (November 2019): 866–74. https://doi.org/10.1016/j.cardfail.2019.07.004.
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• O’Connor, Christopher M. “A Call for Change: Level of Statistical Significance.” Jacc Heart Fail 7, no. 11 (November 2019): 993–94. https://doi.org/10.1016/j.jchf.2019.09.005.
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• Psotka, Mitchell A., Mona Fiuzat, Peter E. Carson, David P. Kao, Jeffrey Cerkvenik, Daniel E. Schaber, Patrick Verta, et al. “Design of a "Lean" Case Report Form for Heart Failure Therapeutic Development.” Jacc Heart Fail 7, no. 11 (November 2019): 913–21. https://doi.org/10.1016/j.jchf.2019.07.001.
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• Truesdell, Alexander G., Behnam Tehrani, Carolyn Rosner, Ramesh Singh, Shashank Sinha, Mehul Desai, Shashank Desai, et al. “After Action Reviews.” J Invasive Cardiol 31, no. 11 (November 2019): E341.
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• Beusekamp, Joost C., Jasper Tromp, John G. F. Cleland, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, John R. Teerlink, et al. “Hyperkalemia and Treatment With RAAS Inhibitors During Acute Heart Failure Hospitalizations and Their Association With Mortality.” Jacc. Heart Failure 7, no. 11 (November 2019): 970–79. https://doi.org/10.1016/j.jchf.2019.07.010.
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• Greene, Stephen J., Adam D. DeVore, Shubin Sheng, Gregg C. Fonarow, Javed Butler, Robert M. Califf, Adrian F. Hernandez, et al. “Representativeness of a Heart Failure Trial by Race and Sex: Results From ASCEND-HF and GWTG-HF.” Jacc Heart Fail 7, no. 11 (November 2019): 980–92. https://doi.org/10.1016/j.jchf.2019.07.011.
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• O’Connor, Christopher M. “Acute Decompensated Heart Failure: Is There a Path Forward?” Jacc Heart Fail 7, no. 10 (October 2019): 911–12. https://doi.org/10.1016/j.jchf.2019.08.005.
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• Januzzi, James L., Tariq Ahmad, Hillary Mulder, Adrian Coles, Kevin J. Anstrom, Kirkwood F. Adams, Justin A. Ezekowitz, et al. “Natriuretic Peptide Response and Outcomes in Chronic Heart Failure With Reduced Ejection Fraction.” J Am Coll Cardiol 74, no. 9 (September 3, 2019): 1205–17. https://doi.org/10.1016/j.jacc.2019.06.055.
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• Grodin, Justin L., Max J. Liebo, Javed Butler, Marco Metra, G Michael Felker, Adrian F. Hernandez, Adriaan A. Voors, et al. “Prognostic Implications of Changes in Amino-Terminal Pro-B-Type Natriuretic Peptide in Acute Decompensated Heart Failure: Insights From ASCEND-HF.” J Card Fail 25, no. 9 (September 2019): 703–11. https://doi.org/10.1016/j.cardfail.2019.04.002.
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• O’Connor, Christopher M. “Heart Failure Physician Burnout: How Can We Help?” Jacc Heart Fail 7, no. 9 (September 2019): 821. https://doi.org/10.1016/j.jchf.2019.07.004.
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• Felker, G Michael, Maria Borentain, John G. Cleland, Mary M. DeSouza, Paul D. Kessler, Christopher M. O’Connor, Dietmar Seiffert, John R. Teerlink, Adriaan A. Voors, and John J. V. McMurray. “Rationale and design for the development of a novel nitroxyl donor in patients with acute heart failure.” Eur J Heart Fail 21, no. 8 (August 2019): 1022–31. https://doi.org/10.1002/ejhf.1504.
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• O’Connor, Christopher M. “Why Should We Publish All Clinical Trials?” Jacc Heart Fail 7, no. 8 (August 2019): 730. https://doi.org/10.1016/j.jchf.2019.06.009.
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• Warraich, Haider J., Christopher M. O’Connor, Hongqiu Yang, Bradi B. Granger, Kimberly S. Johnson, Daniel B. Mark, Kevin J. Anstrom, et al. “African Americans With Advanced Heart Failure Are More Likely to Die in a Health Care Facility Than at Home or in Hospice: An Analysis From the PAL-HF Trial.” Journal of Cardiac Failure 25, no. 8 (August 2019): 693–94. https://doi.org/10.1016/j.cardfail.2019.05.013.
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• Tehrani, Behnam N., and Christopher M. O’Connor. “Reply: Standardized and Tailored Approach to Therapies for Cardiogenic Shock.” J Am Coll Cardiol 74, no. 4 (July 30, 2019): 593–94. https://doi.org/10.1016/j.jacc.2019.05.039.
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• O’Connor, Christopher M. “N-of-1 Clinical Trials.” Jacc Heart Fail 7, no. 7 (July 2019): 630–31. https://doi.org/10.1016/j.jchf.2019.05.004.
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• Blumenthal, James A., Yidan Zhu, Gary G. Koch, Patrick J. Smith, Lana L. Watkins, Alan L. Hinderliter, Benson M. Hoffman, et al. “The modifying effects of social support on psychological outcomes in patients with heart failure.” Health Psychol 38, no. 6 (June 2019): 502–8. https://doi.org/10.1037/hea0000716.
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• O’Connor, Christopher M. “Better Quality of Life Over More Quantity of Life: How We View Time Trade-Off.” Jacc Heart Fail 7, no. 6 (June 2019): 531–32. https://doi.org/10.1016/j.jchf.2019.05.001.
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• Ambrosy, Andrew P., Robert J. Mentz, Mona Fiuzat, John G. F. Cleland, Stephen J. Greene, Christopher M. O’Connor, John R. Teerlink, Faiez Zannad, and Scott D. Solomon. “Erratum to 'The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions' [Eur J Heart Fail 2018;20:963-972].” European Journal of Heart Failure 21, no. 6 (June 2019): 819. https://doi.org/10.1002/ejhf.1480.
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• O’Connor, Christopher, Mona Fiuzat, Hillary Mulder, Adrian Coles, Tariq Ahmad, Justin A. Ezekowitz, Kirkwood F. Adams, et al. “Clinical factors related to morbidity and mortality in high-risk heart failure patients: the GUIDE-IT predictive model and risk score.” Eur J Heart Fail 21, no. 6 (June 2019): 770–78. https://doi.org/10.1002/ejhf.1450.
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• Butler, Javed, Carolyn S. P. Lam, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Burkert Pieske, et al. “Rationale and Design of the VITALITY-HFpEF Trial.” Circ Heart Fail 12, no. 5 (May 2019): e005998. https://doi.org/10.1161/CIRCHEARTFAILURE.119.005998.
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• O’Connor, Christopher M. “Guideline-Directed Medical Therapy Clinics: A Call to Action for the Heart Failure Team.” Jacc Heart Fail 7, no. 5 (May 2019): 442–43. https://doi.org/10.1016/j.jchf.2019.04.001.
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• Russell, Frances M., Robert R. Ehrman, Robinson Ferre, Luna Gargani, Vicki Noble, Jordan Rupp, Sean P. Collins, et al. “Design and rationale of the B-lines lung ultrasound guided emergency department management of acute heart failure (BLUSHED-AHF) pilot trial.” Heart Lung 48, no. 3 (May 2019): 186–92. https://doi.org/10.1016/j.hrtlng.2018.10.027.
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• Psotka, Mitchell A., Susan E. Ammon, Mona Fiuzat, Biykem Bozkurt, Eugene S. Chung, Robert T. Cole, Stephen J. Greene, et al. “Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey.” Jacc Heart Fail 7, no. 5 (May 2019): 431–38. https://doi.org/10.1016/j.jchf.2019.02.008.
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• Taylor, Rod S., Sarah Walker, Neil A. Smart, Massimo F. Piepoli, Fiona C. Warren, Oriana Ciani, David Whellan, et al. “Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis.” J Am Coll Cardiol 73, no. 12 (April 2, 2019): 1430–43. https://doi.org/10.1016/j.jacc.2018.12.072.
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• O’Connor, Christopher M. “Heart Failure Fake News: How Do We Distinguish the Truth?” Jacc Heart Fail 7, no. 4 (April 2019): 363. https://doi.org/10.1016/j.jchf.2019.02.004.
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• Lindenfeld, JoAnn, and Christopher M. O’Connor. “Heart Failure in Women.” Jacc Heart Fail 7, no. 3 (March 2019): 274–75. https://doi.org/10.1016/j.jchf.2019.01.012.
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• Vaduganathan, Muthiah, Ayman Samman Tahhan, Alaaeddin Alrohaibani, Stephen J. Greene, Gregg C. Fonarow, Orly Vardeny, JoAnn Lindenfeld, et al. “Do Women and Men Respond Similarly to Therapies in Contemporary Heart Failure Clinical Trials?” Jacc Heart Fail 7, no. 3 (March 2019): 267–71. https://doi.org/10.1016/j.jchf.2018.12.016.
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• Daubert, Melissa A., Kirkwood Adams, Eric Yow, Huiman X. Barnhart, Pamela S. Douglas, Susan Rimmer, Casey Norris, et al. “NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF.” Jacc Heart Fail 7, no. 2 (February 2019): 158–68. https://doi.org/10.1016/j.jchf.2018.10.014.
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• O’Connor, Christopher M. “Recognizing Heart Failure Awareness Week.” Jacc Heart Fail 7, no. 2 (February 2019): 173. https://doi.org/10.1016/j.jchf.2018.12.013.
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• O’Connor, Christopher M. “JACC: Heart Failure Peer Review Hall of Fame 2018.” Jacc Heart Fail 7, no. 1 (January 2019): 81. https://doi.org/10.1016/j.jchf.2018.12.001.
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• Piccini, Jonathan P., Sean D. Pokorney, Kevin J. Anstrom, Olaf Oldenburg, Naresh M. Punjabi, Mona Fiuzat, Gudaye Tasissa, et al. “Adaptive servo-ventilation reduces atrial fibrillation burden in patients with heart failure and sleep apnea.” Heart Rhythm 16, no. 1 (January 2019): 91–97. https://doi.org/10.1016/j.hrthm.2018.07.027.
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• Luo, Nancy, Christopher M. O’Connor, Lauren B. Cooper, Jie-Lena Sun, Adrian Coles, Shelby D. Reed, David J. Whellan, Ileana L. Piña, William E. Kraus, and Robert J. Mentz. “Relationship between changing patient-reported outcomes and subsequent clinical events in patients with chronic heart failure: insights from HF-ACTION.” European Journal of Heart Failure 21, no. 1 (January 2019): 63–70. https://doi.org/10.1002/ejhf.1299.
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• O’Connor, Christopher M. “Aviation Emergencies for Heart Failure Cardiologists: A New Twist to the Heart Team.” Jacc Heart Fail 6, no. 12 (December 2018): 1047–48. https://doi.org/10.1016/j.jchf.2018.10.018.
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• Taylor, Rod S., Sarah Walker, Neil A. Smart, Massimo F. Piepoli, Fiona C. Warren, Oriana Ciani, Christopher O’Connor, et al. “Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials.” Eur J Heart Fail 20, no. 12 (December 2018): 1735–43. https://doi.org/10.1002/ejhf.1311.
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• Hamo, Carine E., Christopher O’Connor, Marco Metra, James E. Udelson, Mihai Gheorghiade, and Javed Butler. “A Critical Appraisal of Short-Term End Points in Acute Heart Failure Clinical Trials.” J Card Fail 24, no. 11 (November 2018): 783–92. https://doi.org/10.1016/j.cardfail.2018.08.007.
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• O’Connor, Christopher M. “COAPTing Heart Failure Physicians, Interventional Cardiologists, and CardioThoracic Surgeons: A New Opportunity for Patients.” Jacc Heart Fail 6, no. 11 (November 2018): 967–68. https://doi.org/10.1016/j.jchf.2018.09.007.
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• Fudim, Marat, Christopher M. O’Connor, Hillary Mulder, Adrian Coles, Ankeet S. Bhatt, Andrew P. Ambrosy, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Loop diuretic adjustments in patients with chronic heart failure: Insights from HF-ACTION.” American Heart Journal 205 (November 2018): 133–41. https://doi.org/10.1016/j.ahj.2018.06.017.
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• Fudim, Marat, Kishan S. Parikh, Allison Dunning, Adam D. DeVore, Robert J. Mentz, Phillip J. Schulte, Paul W. Armstrong, et al. “Relation of Volume Overload to Clinical Outcomes in Acute Heart Failure (From ASCEND-HF).” Am J Cardiol 122, no. 9 (November 1, 2018): 1506–12. https://doi.org/10.1016/j.amjcard.2018.07.023.
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• Mark, Daniel B., Patricia A. Cowper, Kevin J. Anstrom, Shubin Sheng, Melanie R. Daniels, J David Knight, Khaula N. Baloch, et al. “Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure.” Journal of the American College of Cardiology 72, no. 21 (November 2018): 2551–62. https://doi.org/10.1016/j.jacc.2018.08.2184.
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• Jiang, Wei, David J. Whellan, Kirkwood F. Adams, Michael A. Babyak, Stephen H. Boyle, Jennifer L. Wilson, Chetan B. Patel, Joseph G. Rogers, William S. Harris, and Christopher M. O’Connor. “Long-Chain Omega-3 Fatty Acid Supplements in Depressed Heart Failure Patients: Results of the OCEAN Trial.” Jacc Heart Fail 6, no. 10 (October 2018): 833–43. https://doi.org/10.1016/j.jchf.2018.03.011.
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• O’Connor, Christopher M. “Depression in Heart Failure: Beyond a SADHART.” Jacc Heart Fail 6, no. 10 (October 2018): 885–86. https://doi.org/10.1016/j.jchf.2018.08.004.
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• Tahhan, Ayman Samman, Muthiah Vaduganathan, Stephen J. Greene, Gregg C. Fonarow, Mona Fiuzat, Mariell Jessup, JoAnn Lindenfeld, Christopher M. O’Connor, and Javed Butler. “Enrollment of Older Patients, Women, and Racial and Ethnic Minorities in Contemporary Heart Failure Clinical Trials: A Systematic Review.” Jama Cardiol 3, no. 10 (October 1, 2018): 1011–19. https://doi.org/10.1001/jamacardio.2018.2559.
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• Fudim, Marat, Rahul Loungani, Shannon M. Doerfler, Adrian Coles, Stephen J. Greene, Lauren B. Cooper, Mona Fiuzat, Christopher M. O’Connor, Joseph G. Rogers, and Robert J. Mentz. “Worsening renal function during decongestion among patients hospitalized for heart failure: Findings from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial.” American Heart Journal 204 (October 2018): 163–73. https://doi.org/10.1016/j.ahj.2018.07.019.
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• Greene, Stephen J., Adrian F. Hernandez, Jie-Lena Sun, Javed Butler, Paul W. Armstrong, Justin A. Ezekowitz, Faiez Zannad, et al. “Relationship Between Enrolling Country Income Level and Patient Profile, Protocol Completion, and Trial End Points.” Circulation. Cardiovascular Quality and Outcomes 11, no. 10 (October 2018): e004783. https://doi.org/10.1161/circoutcomes.118.004783.
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• Sharma, Abhinav, Lauren B. Cooper, Mona Fiuzat, Robert J. Mentz, João Pedro Ferreira, Javed Butler, David Fitchett, Alan Charles Moses, Christopher O’Connor, and Faiez Zannad. “Antihyperglycemic Therapies to Treat Patients With Heart Failure and Diabetes Mellitus.” Jacc. Heart Failure 6, no. 10 (October 2018): 813–22. https://doi.org/10.1016/j.jchf.2018.05.020.
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• O’Connor, Christopher M. “Politically Correct Heart Failure Research in America to Avoid Geographic Variation.” Jacc Heart Fail 6, no. 9 (September 2018): 805–6. https://doi.org/10.1016/j.jchf.2018.07.010.
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• Ambrosy, Andrew P., Hillary Mulder, Adrian Coles, William E. Krauss, Carolyn S. P. Lam, Peter A. McCullough, Ileana Pina, et al. “Renal Function and Exercise Training in AmbulatoryHeart Failure Patients With a Reduced Ejection Fraction.” The American Journal of Cardiology 122, no. 6 (September 2018): 999–1007. https://doi.org/10.1016/j.amjcard.2018.06.011.
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• Cooper, Lauren B., Jonathan Yap, Wan Ting Tay, Tiew-Hwa K. Teng, Michael MacDonald, Inder S. Anand, Abhinav Sharma, et al. “Multi-ethnic comparisons of diabetes in heart failure with reduced ejection fraction: insights from the HF-ACTION trial and the ASIAN-HF registry.” European Journal of Heart Failure 20, no. 9 (September 2018): 1281–89. https://doi.org/10.1002/ejhf.1223.
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• Greene, Stephen J., Robert J. Mentz, Mona Fiuzat, Javed Butler, Scott D. Solomon, Andrew P. Ambrosy, Cyrus Mehta, John R. Teerlink, Faiez Zannad, and Christopher M. O’Connor. “Reassessing the Role of Surrogate End Points in Drug Development for Heart Failure.” Circulation 138, no. 10 (September 2018): 1039–53. https://doi.org/10.1161/circulationaha.118.034668.
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• Grodin, Justin L., Javed Butler, Marco Metra, G Michael Felker, Adriaan A. Voors, John J. McMurray, Paul W. Armstrong, et al. “Circulating Cardiac Troponin I Levels Measured by a Novel Highly Sensitive Assay in Acute Decompensated Heart Failure: Insights From the ASCEND-HF Trial.” J Card Fail 24, no. 8 (August 2018): 512–19. https://doi.org/10.1016/j.cardfail.2018.06.008.
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• O’Connor, Christopher M. “HFpEF: From Early Observations to Worldwide Awareness.” Jacc Heart Fail 6, no. 8 (August 2018): 718–19. https://doi.org/10.1016/j.jchf.2018.07.001.
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• Parikh, Kishan S., Kavita Sharma, Mona Fiuzat, Howard K. Surks, Jyothis T. George, Narimon Honarpour, Christopher Depre, et al. “Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials.” Jacc Heart Fail 6, no. 8 (August 2018): 619–32. https://doi.org/10.1016/j.jchf.2018.06.008.
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• Parikh, Kishan S., Mona Fiuzat, Gordon Davis, Megan Neely, Penny Blain-Nelson, David J. Whellan, William T. Abraham, et al. “Dose Response of β-Blockers in Adrenergic Receptor Polymorphism Genotypes.” Circ Genom Precis Med 11, no. 8 (August 2018): e002210. https://doi.org/10.1161/CIRCGEN.117.002210.
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• O’Connor, Christopher M. “Cardiovascular Drug Pricing: Less Innovation for More Access?” Jacc Heart Fail 6, no. 7 (July 2018): 613–14. https://doi.org/10.1016/j.jchf.2018.05.016.
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• Daubert, Melissa A., David J. Whellan, Holger Woehrle, Gudaye Tasissa, Kevin J. Anstrom, JoAnn Lindenfeld, Adam Benjafield, et al. “Treatment of sleep-disordered breathing in heart failure impacts cardiac remodeling: Insights from the CAT-HF Trial.” American Heart Journal 201 (July 2018): 40–48. https://doi.org/10.1016/j.ahj.2018.03.026.
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• Vaduganathan, Muthiah, Ravi B. Patel, Robert J. Mentz, Haris Subacius, Neal A. Chatterjee, Stephen J. Greene, Andrew P. Ambrosy, et al. “Sudden Death After Hospitalization for Heart Failure With Reduced Ejection Fraction (from the EVEREST Trial).” The American Journal of Cardiology 122, no. 2 (July 2018): 255–60. https://doi.org/10.1016/j.amjcard.2018.03.362.
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• Warraich, Haider J., Christopher O’Connor, Angie Wu, Adrian Coles, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Differences Between Patients Enrolled Early and Late During Clinical Trial Recruitment: Insights From the HF-ACTION Trial.” Circulation. Cardiovascular Quality and Outcomes 11, no. 7 (July 2018): e004643. https://doi.org/10.1161/circoutcomes.117.004643.
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• O’Connor, Christopher M. “Dying With Dignity and Heart Failure: A Lesson From Barbara Bush.” Jacc Heart Fail 6, no. 6 (June 2018): 536–37. https://doi.org/10.1016/j.jchf.2018.04.011.
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• Ambrosy, Andrew P., Robert J. Mentz, Mona Fiuzat, John G. F. Cleland, Stephen J. Greene, Christopher M. O’Connor, John R. Teerlink, Faiez Zannad, and Scott D. Solomon. “The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions.” European Journal of Heart Failure 20, no. 6 (June 2018): 963–72. https://doi.org/10.1002/ejhf.1159.
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• Ahmad, Tariq, Keyanna Jackson, Veena S. Rao, WH Wilson Tang, Meredith A. Brisco-Bacik, Horng H. Chen, G Michael Felker, et al. “Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury.” Circulation 137, no. 19 (May 8, 2018): 2016–28. https://doi.org/10.1161/CIRCULATIONAHA.117.030112.
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• Metra, Marco, Gad Cotter, Stefanie Senger, Christopher Edwards, John G. Cleland, Piotr Ponikowski, Guillermo C. Cursack, et al. “Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data.” Circ Heart Fail 11, no. 5 (May 2018): e004644. https://doi.org/10.1161/CIRCHEARTFAILURE.117.004644.
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• O’Connor, Christopher M. “What's One More Day?” Jacc Heart Fail 6, no. 5 (May 2018): 438. https://doi.org/10.1016/j.jchf.2018.03.015.
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• Rubio-Gracia, Jorge, Biniyam G. Demissei, Jozine M. Ter Maaten, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, et al. “Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure.” Int J Cardiol 258 (May 1, 2018): 185–91. https://doi.org/10.1016/j.ijcard.2018.01.067.
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• Ambrosy, Andrew P., Ankeet S. Bhatt, Amanda L. Stebbins, Lisa M. Wruck, Marat Fudim, Stephen J. Greene, William E. Kraus, et al. “Prevalent digoxin use and subsequent risk of death or hospitalization in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) randomized controlled trial.” American Heart Journal 199 (May 2018): 97–104. https://doi.org/10.1016/j.ahj.2018.02.004.
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• Ahmad, Tariq, Lars H. Lund, Pooja Rao, Rohit Ghosh, Prashant Warier, Benjamin Vaccaro, Ulf Dahlström, Christopher M. O’Connor, G Michael Felker, and Nihar R. Desai. “Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients.” J Am Heart Assoc 7, no. 8 (April 12, 2018). https://doi.org/10.1161/JAHA.117.008081.
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• O’Connor, Christopher M., and Michael R. Bristow. “Changing the Research Culture in the United States.” Jacc Heart Fail 6, no. 4 (April 2018): 344–45. https://doi.org/10.1016/j.jchf.2018.03.001.
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• Cerbin, Lukasz P., Andrew P. Ambrosy, Stephen J. Greene, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, et al. “Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial.” Jacc. Heart Failure 6, no. 4 (April 2018): 298–307. https://doi.org/10.1016/j.jchf.2018.01.018.
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• Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.” J Am Coll Cardiol 71, no. 9 (March 6, 2018): 1021–34. https://doi.org/10.1016/j.jacc.2017.12.048.
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• O’Connor, Christopher M. “Heart Failure Health Care 2018: Challenges and Opportunities.” Jacc Heart Fail 6, no. 3 (March 2018): 262–63. https://doi.org/10.1016/j.jchf.2018.01.013.
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• Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.” Circulation 137, no. 9 (February 27, 2018): 961–72. https://doi.org/10.1161/CIRCULATIONAHA.117.033502.
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• Bhatt, Ankeet S., Lauren B. Cooper, Andrew P. Ambrosy, Robert M. Clare, Adrian Coles, Emer Joyce, Arun Krishnamoorthy, et al. “Interaction of Body Mass Index on the Association Between N-Terminal-Pro-b-Type Natriuretic Peptide and Morbidity and Mortality in Patients With Acute Heart Failure: Findings From ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Journal of the American Heart Association 7, no. 3 (February 3, 2018). https://doi.org/10.1161/jaha.117.006740.
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• Cotter, Gad, Marco Metra, Beth A. Davison, Guillaume Jondeau, John G. F. Cleland, Robert C. Bourge, Olga Milo, et al. “Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe?” Eur J Heart Fail 20, no. 2 (February 2018): 317–22. https://doi.org/10.1002/ejhf.889.
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• O’Connor, Christopher M. “Smartphone, Mom, and HFpEF.” Jacc Heart Fail 6, no. 2 (February 2018): 176. https://doi.org/10.1016/j.jchf.2017.12.010.
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• Armstrong, Paul W., Lothar Roessig, Mahesh J. Patel, Kevin J. Anstrom, Javed Butler, Adriaan A. Voors, Carolyn S. P. Lam, et al. “A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Efficacy and Safety of the Oral Soluble Guanylate Cyclase Stimulator: The VICTORIA Trial.” Jacc Heart Fail 6, no. 2 (February 2018): 96–104. https://doi.org/10.1016/j.jchf.2017.08.013.
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• Fudim, Marat, Christopher M. O’Connor, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Adrian Coles, Justin A. Ezekowitz, et al. “Aetiology, timing and clinical predictors of early vs. late readmission following index hospitalization for acute heart failure: insights from ASCEND-HF.” European Journal of Heart Failure 20, no. 2 (February 2018): 304–14. https://doi.org/10.1002/ejhf.1020.
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• O’Connor, Christopher M., Mitchell A. Psotka, Mona Fiuzat, JoAnn Lindenfeld, William T. Abraham, Michael R. Bristow, Daniel Canos, et al. “Improving Heart Failure Therapeutics Development in the United States: The Heart Failure Collaboratory.” J Am Coll Cardiol 71, no. 4 (January 30, 2018): 443–53. https://doi.org/10.1016/j.jacc.2017.11.048.
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• O’Connor, Christopher M. “I Don't Care How Low My BNP Is, I Want to Feel Good.” Jacc Heart Fail 6, no. 1 (January 2018): 82–83. https://doi.org/10.1016/j.jchf.2017.11.004.
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• Pastva, Amy M., Pamela W. Duncan, Gordon R. Reeves, M Benjamin Nelson, David J. Whellan, Christopher M. O’Connor, Joel D. Eggebeen, et al. “Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial.” Contemporary Clinical Trials 64 (January 2018): 118–27. https://doi.org/10.1016/j.cct.2017.10.014.
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• Daubert, Melissa A., Eric Yow, Gary Dunn, Sotir Marchev, Huiman Barnhart, Pamela S. Douglas, Christopher O’Connor, Sidney Goldstein, James E. Udelson, and Hani N. Sabbah. “Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide.” Circ Heart Fail 10, no. 12 (December 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.117.004389.
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• Alenezi, Fawaz, Beverly H. Brummett, Stephen H. Boyle, Zainab Samad, Michael A. Babyak, Nabil Alzaeim, Jennifer Wilson, et al. “Usefulness of Myocardial Annular Velocity Change During Mental Stress to Predict Cardiovascular Outcome in Patients With Coronary Artery Disease (From the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment Trial).” Am J Cardiol 120, no. 9 (November 1, 2017): 1495–1500. https://doi.org/10.1016/j.amjcard.2017.07.039.
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• O’Connor, Christopher M. “Goodbye Mihai: We Will Miss You.” Jacc Heart Fail 5, no. 11 (November 2017): 848–49. https://doi.org/10.1016/j.jchf.2017.09.007.
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• O’Connor, Christopher M. “Q&A With the JACC: Heart Failure Editor-in-Chief: Marking the 5-Year Milestone.” Jacc Heart Fail 5, no. 10 (October 2017): 758–59. https://doi.org/10.1016/j.jchf.2017.08.006.
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• Sharma, Abhinav, Biniyam G. Demissei, Jasper Tromp, Hans L. Hillege, John G. Cleland, Christopher M. O’Connor, Marco Metra, et al. “A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure.” Eur J Heart Fail 19, no. 10 (October 2017): 1310–20. https://doi.org/10.1002/ejhf.912.
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• Sharma, Abhinav, Susanna R. Stevens, Joseph Lucas, Mona Fiuzat, Kirkwood F. Adams, David J. Whellan, Mark P. Donahue, et al. “Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study.” Jacc Heart Fail 5, no. 10 (October 2017): 724–34. https://doi.org/10.1016/j.jchf.2017.07.013.
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• O’Connor, Christopher M. “America and Apple Pie: How Do We Change the American Health Care System?” Jacc Heart Fail 5, no. 9 (September 2017): 686–87. https://doi.org/10.1016/j.jchf.2017.07.006.
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• Sherwood, Andrew, LaBarron K. Hill, James A. Blumenthal, Kirkwood F. Adams, Nicola J. Paine, Gary G. Koch, Christopher M. O’Connor, Kristy S. Johnson, and Alan L. Hinderliter. “Blood pressure reactivity to psychological stress is associated with clinical outcomes in patients with heart failure.” Am Heart J 191 (September 2017): 82–90. https://doi.org/10.1016/j.ahj.2017.07.003.
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• Luo, Nancy, Tiew-Hwa Katherine Teng, Wan Ting Tay, Inder S. Anand, William E. Kraus, Houng Bang Liew, Lieng Hsi Ling, et al. “Multinational and multiethnic variations in health-related quality of life in patients with chronic heart failure.” American Heart Journal 191 (September 2017): 75–81. https://doi.org/10.1016/j.ahj.2017.06.016.
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• O’Connor, Christopher M. “Does Institutional Memory Matter?” Jacc Heart Fail 5, no. 8 (August 2017): 616. https://doi.org/10.1016/j.jchf.2017.07.001.
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• O’Connor, Christopher M. “A Decade With Editorial Mentors: The Day They Dropped the Mic.” Jacc Heart Fail 5, no. 7 (July 2017): 541–42. https://doi.org/10.1016/j.jchf.2017.05.009.
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• Rogers, Joseph G., Chetan B. Patel, Robert J. Mentz, Bradi B. Granger, Karen E. Steinhauser, Mona Fiuzat, Patricia A. Adams, et al. “Palliative Care in Heart Failure: The PAL-HF Randomized, Controlled Clinical Trial.” Journal of the American College of Cardiology 70, no. 3 (July 2017): 331–41. https://doi.org/10.1016/j.jacc.2017.05.030.
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• Tromp, Jasper, Mohsin A. F. Khan, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Biomarker Profiles of Acute Heart Failure Patients With a Mid-Range Ejection Fraction.” Jacc. Heart Failure 5, no. 7 (July 2017): 507–17. https://doi.org/10.1016/j.jchf.2017.04.007.
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• O’Connor, Christopher M. “Development of Acute Decompensated Heart Failure Therapies: Is the Journey Over?” Jacc Heart Fail 5, no. 6 (June 2017): 464–65. https://doi.org/10.1016/j.jchf.2017.04.010.
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• Raslan, Ismail R., Paul Brown, Cynthia M. Westerhout, Justin A. Ezekowitz, Adrian F. Hernandez, Randall C. Starling, Christopher O’Connor, et al. “Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score.” Am Heart J 188 (June 2017): 127–35. https://doi.org/10.1016/j.ahj.2017.03.014.
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• Banks, Adam, Samuel Broderick, Karen Chiswell, Linda Shaw, Adam Devore, Mona Fiuzat, Christopher O’Connor, Gary Michael Felker, Eric Velazquez, and Robert Mentz. “Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease).” The American Journal of Cardiology 119, no. 11 (June 2017): 1703–9. https://doi.org/10.1016/j.amjcard.2017.02.053.
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• Cleland, John G. F., John R. Teerlink, Beth A. Davison, Ahmad Shoaib, Marco Metra, Stefanie Senger, Olga Milo, et al. “Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS).” Eur J Heart Fail 19, no. 6 (June 2017): 739–47. https://doi.org/10.1002/ejhf.786.
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• Demissei, Biniyam G., Douwe Postmus, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “Plasma biomarkers to predict or rule out early post-discharge events after hospitalization for acute heart failure.” Eur J Heart Fail 19, no. 6 (June 2017): 728–38. https://doi.org/10.1002/ejhf.766.
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• Greene, Stephen J., Adrian F. Hernandez, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Javed Butler, Lukasz P. Cerbin, et al. “Hospitalization for Recently Diagnosed Versus Worsening Chronic Heart Failure: From the ASCEND-HF Trial.” Journal of the American College of Cardiology 69, no. 25 (June 2017): 3029–39. https://doi.org/10.1016/j.jacc.2017.04.043.
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• Packer, Milton, Christopher O’Connor, John J. V. McMurray, Janet Wittes, William T. Abraham, Stefan D. Anker, Kenneth Dickstein, et al. “Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure.” N Engl J Med 376, no. 20 (May 18, 2017): 1956–64. https://doi.org/10.1056/NEJMoa1601895.
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• O’Connor, Christopher M. “High Heart Failure Readmission Rates: Is It the Health System's Fault?” Jacc Heart Fail 5, no. 5 (May 2017): 393. https://doi.org/10.1016/j.jchf.2017.03.011.
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• Packer, Milton, Richard Holcomb, William T. Abraham, Stefan Anker, Kenneth Dickstein, Gerasimos Filippatos, Henry Krum, et al. “Rationale for and design of the TRUE-AHF trial: the effects of ularitide on the short-term clinical course and long-term mortality of patients with acute heart failure.” Eur J Heart Fail 19, no. 5 (May 2017): 673–81. https://doi.org/10.1002/ejhf.698.
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• Reeves, Gordon R., David J. Whellan, Christopher M. O’Connor, Pamela Duncan, Joel D. Eggebeen, Timothy M. Morgan, Leigh Ann Hewston, Amy Pastva, Mahesh J. Patel, and Dalane W. Kitzman. “A Novel Rehabilitation Intervention for Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Pilot Study.” Jacc Heart Fail 5, no. 5 (May 2017): 359–66. https://doi.org/10.1016/j.jchf.2016.12.019.
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• Butler, Javed, Carine E. Hamo, James E. Udelson, Christopher O’Connor, Hani N. Sabbah, Marco Metra, Sanjiv J. Shah, et al. “Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations.” Circ Heart Fail 10, no. 4 (April 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003800.
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• O’Connor, Christopher M., and Dirk J. van Veldhuisen. “Data Sharing From the Editors' Perspective: Our Hope With Limitations.” Jacc Heart Fail 5, no. 4 (April 2017): 314–15. https://doi.org/10.1016/j.jchf.2017.02.007.
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• Sun, Julia L., Stephen H. Boyle, Zainab Samad, Michael A. Babyak, Jennifer L. Wilson, Cynthia Kuhn, Richard C. Becker, et al. “Mental stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients.” Eur J Prev Cardiol 24, no. 6 (April 2017): 591–99. https://doi.org/10.1177/2047487316686435.
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• Ambrosy, Andrew P., Lukasz P. Cerbin, Adam D. DeVore, Stephen J. Greene, William E. Kraus, Christopher M. O’Connor, Ileana L. Piña, et al. “Aerobic exercise training and general health status in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)trial.” American Heart Journal 186 (April 2017): 130–38. https://doi.org/10.1016/j.ahj.2016.12.017.
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• Luo, Nancy, Peter Merrill, Kishan S. Parikh, David J. Whellan, Ileana L. Piña, Mona Fiuzat, William E. Kraus, et al. “Exercise Training in Patients With Chronic Heart Failure and Atrial Fibrillation.” Journal of the American College of Cardiology 69, no. 13 (April 2017): 1683–91. https://doi.org/10.1016/j.jacc.2017.01.032.
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• Felker, G Michael, Robert J. Mentz, Robert T. Cole, Kirkwood F. Adams, Gregory F. Egnaczyk, Mona Fiuzat, Chetan B. Patel, et al. “Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure.” J Am Coll Cardiol 69, no. 11 (March 21, 2017): 1399–1406. https://doi.org/10.1016/j.jacc.2016.09.004.
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• O’Connor, Christopher M. “Is Salt Bad for You?” Jacc Heart Fail 5, no. 3 (March 2017): 238–39. https://doi.org/10.1016/j.jchf.2017.01.003.
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• Levy, Wayne C., Yanhong Li, Shelby D. Reed, Michael R. Zile, Ramin Shadman, Todd Dardas, David J. Whellan, et al. “Does the Implantable Cardioverter-Defibrillator Benefit Vary With the Estimated Proportional Risk of Sudden Death in Heart Failure Patients?” Jacc Clin Electrophysiol 3, no. 3 (March 2017): 291–98. https://doi.org/10.1016/j.jacep.2016.09.006.
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• Matsue, Yuya, Jozine M. Ter Maaten, Joachim Struck, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure.” J Card Fail 23, no. 3 (March 2017): 231–39. https://doi.org/10.1016/j.cardfail.2016.09.007.
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• Matsue, Yuya, Peter van der Meer, Kevin Damman, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Blood urea nitrogen-to-creatinine ratio in the general population and in patients with acute heart failure.” Heart 103, no. 6 (March 2017): 407–13. https://doi.org/10.1136/heartjnl-2016-310112.
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• O’Connor, Christopher M., David J. Whellan, Mona Fiuzat, Naresh M. Punjabi, Gudaye Tasissa, Kevin J. Anstrom, Adam V. Benjafield, et al. “Cardiovascular Outcomes With Minute Ventilation-Targeted Adaptive Servo-Ventilation Therapy in Heart Failure: The CAT-HF Trial.” Journal of the American College of Cardiology 69, no. 12 (March 2017): 1577–87. https://doi.org/10.1016/j.jacc.2017.01.041.
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• Reeves, Gordon R., David J. Whellan, Pamela Duncan, Christopher M. O’Connor, Amy M. Pastva, Joel D. Eggebeen, Leigh Ann Hewston, et al. “Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale.” American Heart Journal 185 (March 2017): 130–39. https://doi.org/10.1016/j.ahj.2016.12.012.
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• Feigal, Jacob P., Stephen H. Boyle, Zainab Samad, Eric J. Velazquez, Jennifer L. Wilson, Richard C. Becker, Redford B. Williams, et al. “Associations between positive emotional well-being and stress-induced myocardial ischemia: Well-being scores predict exercise-induced ischemia.” J Psychosom Res 93 (February 2017): 14–18. https://doi.org/10.1016/j.jpsychores.2016.11.012.
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• O’Connor, Christopher M. “21st Century Cures: A Step Forward for Patients With Heart Failure.” Jacc Heart Fail 5, no. 2 (February 2017): 154. https://doi.org/10.1016/j.jchf.2016.12.004.
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• Kitai, Takeshi, Justin L. Grodin, Robert J. Mentz, Adrian F. Hernandez, Javed Butler, Marco Metra, John J. McMurray, et al. “Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial.” European Journal of Heart Failure 19, no. 2 (February 2017): 241–49. https://doi.org/10.1002/ejhf.629.
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• Tromp, Jasper, Jozine M. Ter Maaten, Kevin Damman, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials).” Am J Cardiol 119, no. 2 (January 15, 2017): 290–96. https://doi.org/10.1016/j.amjcard.2016.09.038.
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• Navarese, Eliano P., Paul A. Gurbel, Felicita Andreotti, Michalina Marta Kołodziejczak, Suetonia C. Palmer, Sofia Dias, Antonino Buffon, et al. “Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis.” Plos One 12, no. 2 (2017): e0168726. https://doi.org/10.1371/journal.pone.0168726.
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• O’Connor, C. “HFSA President's Paper (Accepted).” Journal of Cardiac Failure, January 1, 2017. https://doi.org/10.1016/j.cardfail.2017.07.399.
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• O’Connor, Christopher M. “Developing Breakthrough Drugs for Heart Failure: Lessons Learned From the Cystic Fibrosis Experience.” Jacc Heart Fail 5, no. 1 (January 2017): 71–72. https://doi.org/10.1016/j.jchf.2016.11.008.
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• Sherwood, Andrew, James A. Blumenthal, Gary G. Koch, Benson M. Hoffman, Lana L. Watkins, Patrick J. Smith, Christopher M. O’Connor, et al. “Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial.” Circ Heart Fail 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003410.
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• Streng, Koen W., Jozine M. Ter Maaten, John G. Cleland, Christopher M. O’Connor, Beth A. Davison, Marco Metra, Michael M. Givertz, et al. “Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure.” Circ Heart Fail 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003350.
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• Ambrosy, Andrew P., Lukasz P. Cerbin, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, Mark E. Dunlap, et al. “Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From the ASCEND-HF Trial.” Jacc Heart Fail 5, no. 1 (January 2017): 1–13. https://doi.org/10.1016/j.jchf.2016.09.012.
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• Verma, Amanda K., Phillip J. Schulte, Vera Bittner, Steven J. Keteyian, Jerome L. Fleg, Ileana L. Piña, Ann M. Swank, et al. “Socioeconomic and partner status in chronic heart failure: Relationship to exercise capacity, quality of life, and clinical outcomes.” Am Heart J 183 (January 2017): 54–61. https://doi.org/10.1016/j.ahj.2016.10.007.
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• O’Connor, Christopher M. “Not Your Mother's FDA.” Jacc Heart Fail 4, no. 12 (December 2016): 978. https://doi.org/10.1016/j.jchf.2016.10.001.
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• Vegter, Eline L., Daniela Schmitter, Yanick Hagemeijer, Ekaterina S. Ovchinnikova, Pim van der Harst, John R. Teerlink, Christopher M. O’Connor, et al. “Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure.” Int J Cardiol 224 (December 1, 2016): 231–39. https://doi.org/10.1016/j.ijcard.2016.09.010.
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• Demissei, Biniyam G., Douwe Postmus, Licette C. Y. Liu, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, et al. “Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial.” Int J Cardiol 223 (November 15, 2016): 967–75. https://doi.org/10.1016/j.ijcard.2016.08.271.
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• O’Connor, Christopher M. “Peer Review of Peer Review: Somewhere Over the Rainbow.” Jacc Heart Fail 4, no. 11 (November 2016): 907–8. https://doi.org/10.1016/j.jchf.2016.09.005.
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• Cotter, Gad, Beth A. Davison, Olga Milo, Robert C. Bourge, John G. F. Cleland, Guillaume Jondeau, Henry Krum, et al. “Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.” J Card Fail 22, no. 10 (October 2016): 815–22. https://doi.org/10.1016/j.cardfail.2015.12.017.
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• O’Connor, Christopher M. “The International Olympic Games: Heart Teams and Heart Failure.” Jacc Heart Fail 4, no. 10 (October 2016): 826–27. https://doi.org/10.1016/j.jchf.2016.08.004.
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• Parikh, Kishan S., Adrian Coles, Phillip J. Schulte, William E. Kraus, Jerome L. Fleg, Steven J. Keteyian, Ileana L. Piña, et al. “Relation of Angina Pectoris to Outcomes, Quality of Life, and Response to Exercise Training in Patients With Chronic Heart Failure (from HF-ACTION).” The American Journal of Cardiology 118, no. 8 (October 2016): 1211–16. https://doi.org/10.1016/j.amjcard.2016.07.040.
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• Tromp, Jasper, Sven Meyer, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Acute heart failure in the young: Clinical characteristics and biomarker profiles.” International Journal of Cardiology 221 (October 2016): 1067–72. https://doi.org/10.1016/j.ijcard.2016.06.339.
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• O’Connor, Christopher M. “The Mentor's Mentor: The Life of Galen Wagner.” Jacc Heart Fail 4, no. 9 (September 2016): 759. https://doi.org/10.1016/j.jchf.2016.07.009.
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• Greene, Stephen J., Adrian F. Hernandez, Jie-Lena Sun, Marco Metra, Javed Butler, Andrew P. Ambrosy, Justin A. Ezekowitz, et al. “Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Circulation. Heart Failure 9, no. 9 (September 2016). https://doi.org/10.1161/circheartfailure.116.002986.
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• Luo, Nancy, Joseph G. Rogers, Gwen C. Dodson, Chetan B. Patel, Anthony N. Galanos, Carmelo A. Milano, Christopher M. O’Connor, and Robert J. Mentz. “Usefulness of Palliative Care to Complement the Management of Patients on Left Ventricular Assist Devices.” The American Journal of Cardiology 118, no. 5 (September 2016): 733–38. https://doi.org/10.1016/j.amjcard.2016.06.010.
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• Davison, Beth A., Marco Metra, Stefanie Senger, Christopher Edwards, Olga Milo, Daniel M. Bloomfield, John G. Cleland, et al. “Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality.” Eur J Heart Fail 18, no. 8 (August 2016): 1041–50. https://doi.org/10.1002/ejhf.540.
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• O’Connor, Christopher M. “Can Academic Cardiology Divisions Survive?” Jacc Heart Fail 4, no. 8 (August 2016): 687–88. https://doi.org/10.1016/j.jchf.2016.06.001.
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• Kelly, Jacob P., Allison Dunning, Phillip J. Schulte, Mona Fiuzat, Eric S. Leifer, Jerome L. Fleg, Lawton S. Cooper, et al. “Statins and Exercise Training Response in Heart Failure Patients: Insights From HF-ACTION.” Jacc. Heart Failure 4, no. 8 (August 2016): 617–24. https://doi.org/10.1016/j.jchf.2016.05.006.
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• Kelly, Jacob P., Lauren B. Cooper, Dianne Gallup, Kevin J. Anstrom, Horng H. Chen, Margaret M. Redfield, Christopher M. O’Connor, Robert J. Mentz, Adrian F. Hernanadez, and G Michael Felker. “Implications of Using Different Definitions on Outcomes in Worsening Heart Failure.” Circulation. Heart Failure 9, no. 8 (August 2016). https://doi.org/10.1161/circheartfailure.116.003048.
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• Paine, Nicola J., Alan L. Hinderliter, James A. Blumenthal, Kirkwood F. Adams, Carla A. Sueta, Patricia P. Chang, Christopher M. O’Connor, and Andrew Sherwood. “Reactive hyperemia is associated with adverse clinical outcomes in heart failure.” Am Heart J 178 (August 2016): 108–14. https://doi.org/10.1016/j.ahj.2016.05.008.
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• Ter Maaten, Jozine M., Kevin Damman, Jennifer S. Hanberg, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, John R. Teerlink, et al. “Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure.” Circ Heart Fail 9, no. 8 (August 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003109.
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• Biegus, Jan, Hans L. Hillege, Douwe Postmus, Mattia A. E. Valente, Daniel M. Bloomfield, John G. F. Cleland, Gad Cotter, et al. “Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study.” Eur J Heart Fail 18, no. 7 (July 2016): 830–39. https://doi.org/10.1002/ejhf.532.
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• Denardo, Scott J., David M. Vock, Carsten M. Schmalfuss, Gregory D. Young, James E. Tcheng, and Christopher M. O’Connor. “Baseline Hemodynamics and Response to Contrast Media During Diagnostic Cardiac Catheterization Predict Adverse Events in Heart Failure Patients.” Circ Heart Fail 9, no. 7 (July 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002529.
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• O’Connor, Christopher M. “The Year in Heart Failure Review 2015 to 2016.” Jacc Heart Fail 4, no. 7 (July 2016): 603–4. https://doi.org/10.1016/j.jchf.2016.05.005.
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• Banks, Adam Z., Robert J. Mentz, Amanda Stebbins, Catherine R. Mikus, Phillip J. Schulte, Jerome L. Fleg, Lawton S. Cooper, et al. “Response to Exercise Training and Outcomes in Patients With Heart Failure and Diabetes Mellitus: Insights From the HF-ACTION Trial.” Journal of Cardiac Failure 22, no. 7 (July 2016): 485–91. https://doi.org/10.1016/j.cardfail.2015.12.007.
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• Reeves, Gordon R., David J. Whellan, Mahesh J. Patel, Christopher M. O’Connor, Pamela Duncan, Joel D. Eggebeen, Timothy M. Morgan, Leigh A. Hewston, Amy M. Pastva, and Dalane W. Kitzman. “Comparison of Frequency of Frailty and Severely Impaired Physical Function in Patients ≥60 Years Hospitalized With Acute Decompensated Heart Failure Versus Chronic Stable Heart Failure With Reduced and Preserved Left Ventricular Ejection Fraction.” Am J Cardiol 117, no. 12 (June 15, 2016): 1953–58. https://doi.org/10.1016/j.amjcard.2016.03.046.
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• Emmens, Johanna E., Jozine M. Ter Maaten, Yuya Matsue, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome.” Eur J Heart Fail 18, no. 6 (June 2016): 641–49. https://doi.org/10.1002/ejhf.426.
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• O’Connor, Christopher M. “Social Media: Can It Reduce Heart Failure Events?” Jacc Heart Fail 4, no. 6 (June 2016): 514–15. https://doi.org/10.1016/j.jchf.2016.04.006.
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• Ter Maaten, Jozine M., Mattia A. E. Valente, Kevin Damman, John G. Cleland, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, et al. “Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure.” Circ Heart Fail 9, no. 6 (June 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002845.
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• Whellan, David J., Amanda Stebbins, Adrian F. Hernandez, Justin A. Ezekowitz, John J. V. McMurray, Paul J. Mather, Vic Hasselblad, and Christopher M. O’Connor. “Dichotomous Relationship Between Age and 30-Day Death or Rehospitalization in Heart Failure Patients Admitted With Acute Decompensated Heart Failure: Results From the ASCEND-HF Trial.” J Card Fail 22, no. 6 (June 2016): 409–16. https://doi.org/10.1016/j.cardfail.2016.02.011.
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• Metra, Marco, Robert J. Mentz, Adrian F. Hernandez, Gretchen M. Heizer, Paul W. Armstrong, Nadine Clausell, Ramon Corbalan, et al. “Geographic Differences in Patients in a Global Acute Heart Failure Clinical Trial (from the ASCEND-HF Trial).” The American Journal of Cardiology 117, no. 11 (June 2016): 1771–78. https://doi.org/10.1016/j.amjcard.2016.03.002.
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• Wong, Yee Weng, Robert J. Mentz, G Michael Felker, Justin Ezekowitz, Karen Pieper, Gretchen Heizer, Vic Hasselblad, et al. “Nesiritide in patients hospitalized for acute heart failure: does timing matter? Implication for future acute heart failure trials.” European Journal of Heart Failure 18, no. 6 (June 2016): 684–92. https://doi.org/10.1002/ejhf.487.
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• Navarese, Eliano P., Michalina Kolodziejczak, Dean J. Kereiakes, Udaya S. Tantry, Christopher O’Connor, and Paul A. Gurbel. “Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review.” Annals of Internal Medicine 164, no. 9 (May 2016): 600–607. https://doi.org/10.7326/m15-2994.
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• O’Connor, Christopher M., Mona Fiuzat, and JoAnn Lindenfeld. “Are We Really in Love With Old Therapies?” Jacc Heart Fail, April 12, 2016. https://doi.org/10.1016/j.jchf.2016.02.011.
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• Ovchinnikova, Ekaterina S., Daniela Schmitter, Eline L. Vegter, Jozine M. Ter Maaten, Mattia A. E. Valente, Licette C. Y. Liu, Pim van der Harst, et al. “Signature of circulating microRNAs in patients with acute heart failure.” Eur J Heart Fail 18, no. 4 (April 2016): 414–23. https://doi.org/10.1002/ejhf.332.
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• O’Connor, Christopher M. “Why Negative Trials Are Positive for Heart Failure Patients.” Jacc Heart Fail 4, no. 4 (April 2016): 329–30. https://doi.org/10.1016/j.jchf.2016.02.010.
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• Rosendorff, Clive, and Clive Writing Committee. “Treatment of Hypertension in Patients with Coronary Artery Disease. A Case-Based Summary of the 2015 AHA/ACC/ASH Scientific Statement.” Am J Med 129, no. 4 (April 2016): 372–78. https://doi.org/10.1016/j.amjmed.2015.10.045.
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• Garber, Adam M., Robert J. Mentz, Hussein R. Al-Khalidi, Linda K. Shaw, Mona Fiuzat, Christopher M. O’Connor, and Eric J. Velazquez. “Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction.” Journal of Thrombosis and Thrombolysis 41, no. 3 (April 2016): 365–73. https://doi.org/10.1007/s11239-015-1252-0.
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• Samsky, Marc D., Allison Dunning, Adam D. DeVore, Phillip J. Schulte, Randall C. Starling, WH Wilson Tang, Paul W. Armstrong, et al. “Liver function tests in patients with acute heart failure and associated outcomes: insights from ASCEND-HF.” European Journal of Heart Failure 18, no. 4 (April 2016): 424–32. https://doi.org/10.1002/ejhf.440.
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• Ezekowitz, Justin A., Mohua Podder, Adrian F. Hernandez, Paul W. Armstrong, Randall C. Starling, Christopher M. O’Connor, and Robert M. Califf. “Arrival by ambulance in acute heart failure: insights into the mode of presentation from Acute Studies of Nesiritide in Decompensated Heart Failure (ASCEND-HF).” Bmj Open 6, no. 3 (March 17, 2016): e010201. https://doi.org/10.1136/bmjopen-2015-010201.
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• Demissei, Biniyam G., Mattia A. E. Valente, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “Optimizing clinical use of biomarkers in high-risk acute heart failure patients.” Eur J Heart Fail 18, no. 3 (March 2016): 269–80. https://doi.org/10.1002/ejhf.443.
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• Fiuzat, Mona, Olaf Oldenberg, David J. Whellan, Holger Woehrle, Naresh M. Punjabi, Kevin J. Anstrom, Amy B. Blase, Adam V. Benjafield, JoAnn Lindenfeld, and Christopher M. O’Connor. “Lessons learned from a clinical trial: Design, rationale, and insights from The Cardiovascular Improvements with Minute Ventilation-targeted Adaptive Sero-Ventilation (ASV) Therapy in Heart Failure (CAT-HF) Study.” Contemp Clin Trials 47 (March 2016): 158–64. https://doi.org/10.1016/j.cct.2016.01.001.
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• O’Connor, Christopher M. “I Lost a Friend From HFpEF: William Anlyan, MD, Chancellor Emeritus and Duke University Trustee.” Jacc Heart Fail 4, no. 3 (March 2016): 230–31. https://doi.org/10.1016/j.jchf.2016.01.007.
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• Perez, Antonio L., Justin L. Grodin, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, G Michael Felker, et al. “Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy.” Eur J Heart Fail 18, no. 3 (March 2016): 290–97. https://doi.org/10.1002/ejhf.456.
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• Ambrosy, Andrew P., Adrian F. Hernandez, Paul W. Armstrong, Javed Butler, Allison Dunning, Justin A. Ezekowitz, G Michael Felker, et al. “The clinical course of health status and association with outcomes in patients hospitalized for heart failure: insights from ASCEND-HF.” European Journal of Heart Failure 18, no. 3 (March 2016): 306–13. https://doi.org/10.1002/ejhf.420.
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• Cooper, Lauren B., Robert J. Mentz, Susanna R. Stevens, G Michael Felker, Carlo Lombardi, Marco Metra, Lynne W. Stevenson, et al. “Hemodynamic Predictors of Heart Failure Morbidity and Mortality: Fluid or Flow?” J Card Fail 22, no. 3 (March 2016): 182–89. https://doi.org/10.1016/j.cardfail.2015.11.012.
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• Keteyian, Steven J., Mahesh Patel, William E. Kraus, Clinton A. Brawner, Timothy R. McConnell, Ileana L. Piña, Eric S. Leifer, et al. “Variables Measured During Cardiopulmonary Exercise Testing as Predictors of Mortality in Chronic Systolic Heart Failure.” J Am Coll Cardiol 67, no. 7 (February 23, 2016): 780–89. https://doi.org/10.1016/j.jacc.2015.11.050.
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• Demissei, Biniyam G., John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, Beth Davison, et al. “Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients.” Int J Cardiol 204 (February 1, 2016): 164–71. https://doi.org/10.1016/j.ijcard.2015.11.141.
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• Fiuzat, Mona, Daniel Wojdyla, Ileana Pina, Kirkwood Adams, David Whellan, and Christopher M. O’Connor. “Heart Rate or Beta-Blocker Dose? Association With Outcomes in Ambulatory Heart Failure Patients With Systolic Dysfunction: Results From the HF-ACTION Trial.” Jacc Heart Fail 4, no. 2 (February 2016): 109–15. https://doi.org/10.1016/j.jchf.2015.09.002.
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• Maaten, Jozine M. ter, Mattia A. E. Valente, Marco Metra, Noemi Bruno, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “A combined clinical and biomarker approach to predict diuretic response in acute heart failure.” Clin Res Cardiol 105, no. 2 (February 2016): 145–53. https://doi.org/10.1007/s00392-015-0896-2.
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• Mark, Daniel B., and Christopher M. O’Connor. “When Business and Science Clash, How Can We Avoid Harming Patients?: The Case of AVOID-HF.” Jacc Heart Fail 4, no. 2 (February 2016): 106–8. https://doi.org/10.1016/j.jchf.2015.09.001.
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• O’Connor, Christopher M. “Death of the Heart Failure Clinical Investigator: Molecules and Receptors Win Nobel Prizes, Clinical Investigation Improves Survival.” Jacc Heart Fail 4, no. 2 (February 2016): 162–63. https://doi.org/10.1016/j.jchf.2015.12.001.
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• Mentz, Robert J., Vic Hasselblad, Adam D. DeVore, Marco Metra, Adriaan A. Voors, Paul W. Armstrong, Justin A. Ezekowitz, et al. “Torsemide Versus Furosemide in Patients With Acute Heart Failure (from the ASCEND-HF Trial).” The American Journal of Cardiology 117, no. 3 (February 2016): 404–11. https://doi.org/10.1016/j.amjcard.2015.10.059.
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• Ahmad, Tariq, Jacob P. Kelly, Robert W. McGarrah, Anne S. Hellkamp, Mona Fiuzat, Jeffrey M. Testani, Teresa S. Wang, et al. “Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support.” J Am Coll Cardiol 67, no. 3 (January 26, 2016): 291–99. https://doi.org/10.1016/j.jacc.2015.10.079.
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• Bruno, Noemi, Jozine M. ter Maaten, Ekaterina S. Ovchinnikova, Eline L. Vegter, Mattia A. E. Valente, Peter van der Meer, Rudolf A. de Boer, et al. “MicroRNAs relate to early worsening of renal function in patients with acute heart failure.” Int J Cardiol 203 (January 15, 2016): 564–69. https://doi.org/10.1016/j.ijcard.2015.10.217.
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• O’Connor, Christopher M. “Why Dr. Robert Califf's Nomination for Commissioner of the Food and Drug Administration Is Good for Heart Failure Patients.” Jacc Heart Fail 4, no. 1 (January 2016): 90–91. https://doi.org/10.1016/j.jchf.2015.11.004.
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• Tang, WH Wilson, Yuping Wu, Justin L. Grodin, Amy P. Hsu, Adrian F. Hernandez, Javed Butler, Marco Metra, et al. “Prognostic Value of Baseline and Changes in Circulating Soluble ST2 Levels and the Effects of Nesiritide in Acute Decompensated Heart Failure.” Jacc Heart Fail 4, no. 1 (January 2016): 68–77. https://doi.org/10.1016/j.jchf.2015.07.015.
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• Ahmad, Tariq, Nihar Desai, Francis Wilson, Phillip Schulte, Allison Dunning, Daniel Jacoby, Larry Allen, et al. “Clinical Implications of Cluster Analysis-Based Classification of Acute Decompensated Heart Failure and Correlation with Bedside Hemodynamic Profiles.” Plos One 11, no. 2 (January 2016): e0145881. https://doi.org/10.1371/journal.pone.0145881.
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• Mentz, R., and C. O’Connor. “Pathophysiology and clinical evaluation of acute heart failure.” Nature Reviews Cardiology 13, no. 1 (January 1, 2016): 28–35. https://doi.org/10.1038/nrcardio.2015.134.
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• Brunner-La Rocca, Hans-Peter, Luc Eurlings, A Mark Richards, James L. Januzzi, Matthias E. Pfisterer, Ulf Dahlström, Yigal M. Pinto, et al. “Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials.” Eur J Heart Fail 17, no. 12 (December 2015): 1252–61. https://doi.org/10.1002/ejhf.401.
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• O’Connor, Christopher M. “Heart Failure "End Result Cards": Solid B.” Jacc Heart Fail 3, no. 12 (December 2015): 1001–2. https://doi.org/10.1016/j.jchf.2015.10.004.
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• O’Connor, Christopher M. “Bundle Up for Value-Based Heart Failure Care.” Jacc Heart Fail 3, no. 11 (November 2015): 931–32. https://doi.org/10.1016/j.jchf.2015.09.003.
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• Cooper, Lauren B., Robert J. Mentz, Jie-Lena Sun, Phillip J. Schulte, Jerome L. Fleg, Lawton S. Cooper, Ileana L. Piña, et al. “Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION).” Circulation. Heart Failure 8, no. 6 (November 2015): 1044–51. https://doi.org/10.1161/circheartfailure.115.002327.
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• Samad, Zainab, Linda K. Shaw, Matthew Phelan, Mads Ersboll, Niels Risum, Hussein R. Al-Khalidi, Donald D. Glower, et al. “Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction.” Eur Heart J 36, no. 40 (October 21, 2015): 2733–41. https://doi.org/10.1093/eurheartj/ehv343.
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• Grodin, Justin L., Antonio L. Perez, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, G Michael Felker, et al. “Circulating Kidney Injury Molecule-1 Levels in Acute Heart Failure: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Jacc Heart Fail 3, no. 10 (October 2015): 777–85. https://doi.org/10.1016/j.jchf.2015.06.006.
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• O’Connor, Christopher M. “Physician-Leaders: A Call for Cardiovascular Specialists to Step Up.” Jacc Heart Fail 3, no. 10 (October 2015): 843–44. https://doi.org/10.1016/j.jchf.2015.08.004.
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• Mentz, Robert J., Eric J. Velazquez, Marco Metra, Colleen McKendry, Karen Chiswell, Mona Fiuzat, Michael M. Givertz, Adriaan A. Voors, John R. Teerlink, and Christopher M. O’Connor. “Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial.” Future Cardiology 11, no. 5 (September 25, 2015): 585–95. https://doi.org/10.2217/fca.15.56.
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• O’Connor, Christopher M. “What Is a Life Worth?: A Tribute to Dr. William Little, a Pioneer in the Understanding of Heart Failure With Preserved Ejection Fraction.” Jacc Heart Fail 3, no. 9 (September 2015): 734–35. https://doi.org/10.1016/j.jchf.2015.07.002.
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• Xiong, Glen L., Kevin Prybol, Stephen H. Boyle, Russell Hall, Robert D. Streilein, David C. Steffens, Ranga Krishnan, et al. “Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study.” Psychosom Med 77, no. 7 (September 2015): 808–15. https://doi.org/10.1097/PSY.0000000000000216.
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• Felker, G Michael, Robert J. Mentz, Kirkwood F. Adams, Robert T. Cole, Gregory F. Egnaczyk, Chetan B. Patel, Mona Fiuzat, et al. “Tolvaptan in Patients Hospitalized With Acute Heart Failure: Rationale and Design of the TACTICS and the SECRET of CHF Trials.” Circulation. Heart Failure 8, no. 5 (September 2015): 997–1005. https://doi.org/10.1161/circheartfailure.115.002259.
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• Abualnaja, Seraj, Mohua Podder, Adrian F. Hernandez, John J. V. McMurray, Randall C. Starling, Christopher M. O’Connor, Robert M. Califf, Paul W. Armstrong, and Justin A. Ezekowitz. “Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) Trial.” J Am Heart Assoc 4, no. 8 (August 24, 2015): e002092. https://doi.org/10.1161/JAHA.115.002092.
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• O’Connor, Christopher M., and Tariq Ahmad. “The Role of Sodium and Chloride in Heart Failure: Does It Take Two to Tango?” J Am Coll Cardiol 66, no. 6 (August 11, 2015): 667–69. https://doi.org/10.1016/j.jacc.2015.05.070.
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• Farzaneh-Far, Afshin, Linda K. Shaw, Allison Dunning, Jorge D. Oldan, Christopher M. O’Connor, and Salvador Borges-Neto. “Comparison of the prognostic value of regadenoson and adenosine myocardial perfusion imaging.” J Nucl Cardiol 22, no. 4 (August 2015): 600–607. https://doi.org/10.1007/s12350-015-0155-y.
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• Hess, Paul L., Linda K. Shaw, Sreekanth Vemulapalli, Robert Pagnanelli, Christopher M. O’Connor, and Salvador Borges-Neto. “An alternative method to examine the predictive value of mechanical dyssynchrony.” J Nucl Cardiol 22, no. 4 (August 2015): 686–89. https://doi.org/10.1007/s12350-015-0145-0.
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• Khazanie, Prateeti, Gretchen M. Heizer, Vic Hasselblad, Paul W. Armstrong, Robert M. Califf, Justin Ezekowitz, Kenneth Dickstein, et al. “Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models.” Am Heart J 170, no. 2 (August 2015): 290–97. https://doi.org/10.1016/j.ahj.2015.04.006.
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• Maaten, Jozine M. ter, Allison M. Dunning, Mattia A. E. Valente, Kevin Damman, Justin A. Ezekowitz, Robert M. Califf, Randall C. Starling, et al. “Diuretic response in acute heart failure-an analysis from ASCEND-HF.” Am Heart J 170, no. 2 (August 2015): 313–21. https://doi.org/10.1016/j.ahj.2015.05.003.
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• O’Connor, Christopher M. “The Globalization of Heart Failure Research.” Jacc Heart Fail 3, no. 8 (August 2015): 657–58. https://doi.org/10.1016/j.jchf.2015.06.001.
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• Filippatos, Gerasimos, Joseph Rossi, Donald M. Lloyd-Jones, Wendy Gattis Stough, John Ouyang, David D. Shin, Christopher O’connor, Kirkwood F. Adams, Cesare Orlandi, and Mihai Gheorghiade. “Prognostic value of blood urea nitrogen in patients hospitalized with worsening heart failure: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) study.” J Card Fail 13, no. 5 (June 2007): 360–64. https://doi.org/10.1016/j.cardfail.2007.02.005.
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• Rosendorff, Clive, Henry R. Black, Christopher P. Cannon, Bernard J. Gersh, Joel Gore, Joseph L. Izzo, Norman M. Kaplan, et al. “Treatment of hypertension in the prevention and management of ischemic heart disease: a scientific statement from the American Heart Association Council for High Blood Pressure Research and the Councils on Clinical Cardiology and Epidemiology and Prevention.” Circulation 115, no. 21 (May 29, 2007): 2761–88. https://doi.org/10.1161/CIRCULATIONAHA.107.183885.
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• Bourque, Jamieson M., Eric J. Velazquez, Robert H. Tuttle, Linda K. Shaw, Christopher M. O’Connor, and Salvador Borges-Neto. “Mortality risk associated with ejection fraction differs across resting nuclear perfusion findings.” J Nucl Cardiol 14, no. 2 (April 2007): 165–73. https://doi.org/10.1016/j.nuclcard.2006.11.011.
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• Gheorghiade, Mihai, William T. Abraham, Nancy M. Albert, Wendy Gattis Stough, Barry H. Greenberg, Christopher M. O’Connor, Lilin She, et al. “Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry.” Eur Heart J 28, no. 8 (April 2007): 980–88. https://doi.org/10.1093/eurheartj/ehl542.
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• Gold, M. R., and C. O’Connor. “Introduction.” American Heart Journal 153, no. 4 SUPPL. (April 1, 2007): 1. https://doi.org/10.1016/j.ahj.2007.01.012.
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• O’Connor, Christopher M. “The new heart failure guidelines: strategies for implementation.” Am Heart J 153, no. 4 Suppl (April 2007): 2–5. https://doi.org/10.1016/j.ahj.2007.01.010.
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• Phillips, Harry R., Christopher M. O’Connor, and Joseph Rogers. “Revascularization for heart failure.” Am Heart J 153, no. 4 Suppl (April 2007): 65–73. https://doi.org/10.1016/j.ahj.2007.01.026.
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• Albert, Nancy M., Gregg C. Fonarow, William T. Abraham, Karen Chiswell, Wendy Gattis Stough, Mihai Gheorghiade, Barry H. Greenberg, et al. “Predictors of delivery of hospital-based heart failure patient education: a report from OPTIMIZE-HF.” J Card Fail 13, no. 3 (April 2007): 189–98. https://doi.org/10.1016/j.cardfail.2006.11.008.
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• Allen, Larry A., and Christopher M. O’Connor. “Management of acute decompensated heart failure.” Cmaj 176, no. 6 (March 13, 2007): 797–805. https://doi.org/10.1503/cmaj.051620.
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• Arumugham, Pradeep S., and Christopher M. O’Connor. “Nonpharmacologic therapy in heart failure: an overview.” Curr Heart Fail Rep 4, no. 1 (March 2007): 33–38. https://doi.org/10.1007/s11897-007-0023-4.
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• Malinin, Alex I., Benjamin R. Oshrine, David C. Sane, Christopher M. O’Connor, and Victor L. Serebruany. “Does heart failure etiology, New York Heart Association class, or ejection fraction affect the ability of clopidogrel to inhibit heightened platelet activity?” Blood Coagul Fibrinolysis 18, no. 2 (March 2007): 91–96. https://doi.org/10.1097/MBC.0b013e32801455db.
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• Sherwood, Andrew, James A. Blumenthal, Ranak Trivedi, Kristy S. Johnson, Christopher M. O’Connor, Kirkwood F. Adams, Carla Sueta Dupree, et al. “Relationship of depression to death or hospitalization in patients with heart failure.” Arch Intern Med 167, no. 4 (February 26, 2007): 367–73. https://doi.org/10.1001/archinte.167.4.367.
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• Milo-Cotter, Olga, Kirkwood F. Adams, Christopher M. O’Connor, Nir Uriel, Edo Kaluski, G Michael Felker, Beth Weatherley, Zvi Vered, and Gad Cotter. “Acute heart failure associated with high admission blood pressure--a distinct vascular disorder?” Eur J Heart Fail 9, no. 2 (February 2007): 178–83. https://doi.org/10.1016/j.ejheart.2006.06.004.
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• O’Connor, Christopher M., and Pradeep Arumugham. “Inotropic drugs and neurohormonal antagonists in the treatment of HF in the elderly.” Clin Geriatr Med 23, no. 1 (February 2007): 141–53. https://doi.org/10.1016/j.cger.2006.09.001.
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• Whellan, David J., Christopher M. O’Connor, Kerry L. Lee, Steven J. Keteyian, Lawton S. Cooper, Stephen J. Ellis, Eric S. Leifer, et al. “Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale.” Am Heart J 153, no. 2 (February 2007): 201–11. https://doi.org/10.1016/j.ahj.2006.11.007.
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• Whellan, David J., Shelby D. Reed, Lawrence Liao, Stuart D. Gould, Christopher M. O’connor, and Kevin A. Schulman. “Financial implications of a model heart failure disease management program for providers, hospital, healthcare systems, and payer perspectives.” Am J Cardiol 99, no. 2 (January 15, 2007): 256–60. https://doi.org/10.1016/j.amjcard.2006.08.019.
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• Fonarow, Gregg C., William T. Abraham, Nancy M. Albert, Wendy Gattis Stough, Mihai Gheorghiade, Barry H. Greenberg, Christopher M. O’Connor, et al. “Association between performance measures and clinical outcomes for patients hospitalized with heart failure.” Jama 297, no. 1 (January 3, 2007): 61–70. https://doi.org/10.1001/jama.297.1.61.
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• Fonarow, Gregg C., William T. Abraham, Nancy M. Albert, Wendy Gattis Stough, Mihai Gheorghiade, Barry H. Greenberg, Christopher M. O’Connor, et al. “Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: an analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).” Am Heart J 153, no. 1 (January 2007): 82.e1-82.11. https://doi.org/10.1016/j.ahj.2006.10.008.
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• Rossi, Joseph, Melike Bayram, James E. Udelson, Donald Lloyd-Jones, Kirkwood F. Adams, Christopher M. Oconnor, Wendy Gattis Stough, et al. “Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) trial.” Acute Card Care 9, no. 2 (2007): 82–86. https://doi.org/10.1080/17482940701210179.
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• Echols, Melvin R., G Michael Felker, Kevin L. Thomas, Karen S. Pieper, Jyotsna Garg, Michael S. Cuffe, Mihai Gheorghiade, Robert M. Califf, and Christopher M. O’Connor. “Racial differences in the characteristics of patients admitted for acute decompensated heart failure and their relation to outcomes: results from the OPTIME-CHF trial.” J Card Fail 12, no. 9 (December 2006): 684–88. https://doi.org/10.1016/j.cardfail.2006.08.003.
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• Gheorghiade, Mihai, William T. Abraham, Nancy M. Albert, Barry H. Greenberg, Christopher M. O’Connor, Lilin She, Wendy Gattis Stough, et al. “Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure.” Jama 296, no. 18 (November 8, 2006): 2217–26. https://doi.org/10.1001/jama.296.18.2217.
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• Bourque, Jamieson M., Christopher M. O’Connor, and Eric J. Velazquez. “Letter by Bourque et al regarding article, "Changing incidence and survival for heart failure in a well-defined older population, 1970-1974 and 1990-1994".” Circulation 114, no. 7 (August 15, 2006): e255. https://doi.org/10.1161/CIRCULATIONAHA.106.632786.
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• Aguilar, David, Marian R. Fisher, Christopher M. O’Connor, Michael W. Dunne, Joseph B. Muhlestein, Louis Yao, Sandeep Gupta, et al. “Metabolic syndrome, C-reactive protein, and prognosis in patients with established coronary artery disease.” Am Heart J 152, no. 2 (August 2006): 298–304. https://doi.org/10.1016/j.ahj.2005.11.011.
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• Whellan, David J., Robert H. Tuttle, Eric J. Velazquez, Linda K. Shaw, James G. Jollis, Wendell Ellis, Christopher M. O’Connor, Robert M. Califf, and Salvador Borges-Neto. “Predicting significant coronary artery disease in patients with left ventricular dysfunction.” American Heart Journal 152, no. 2 (August 2006): 340–47. https://doi.org/10.1016/j.ahj.2005.12.001.
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• Jaffe, Allan S., Harlan M. Krumholz, Diane J. Catellier, Kenneth E. Freedland, Vera Bittner, James A. Blumenthal, James E. Calvin, et al. “Prediction of medical morbidity and mortality after acute myocardial infarction in patients at increased psychosocial risk in the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) study.” Am Heart J 152, no. 1 (July 2006): 126–35. https://doi.org/10.1016/j.ahj.2005.10.004.
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• Xiong, Glen L., Wei Jiang, Robert Clare, Linda K. Shaw, Peter K. Smith, Kenneth W. Mahaffey, Christopher M. O’Connor, K Ranga R. Krishnan, and L Kristin Newby. “Prognosis of patients taking selective serotonin reuptake inhibitors before coronary artery bypass grafting.” Am J Cardiol 98, no. 1 (July 1, 2006): 42–47. https://doi.org/10.1016/j.amjcard.2006.01.051.
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• Janardhanan, Rajesh, Satish Kenchaiah, Eric J. Velazquez, Yuhyun Park, John J. V. McMurray, W Douglas Weaver, Peter V. Finn, et al. “Extent of coronary artery disease as a predictor of outcomes in acute myocardial infarction complicated by heart failure, left ventricular dysfunction, or both.” American Heart Journal 152, no. 1 (July 2006): 183–89. https://doi.org/10.1016/j.ahj.2005.11.013.
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• Butler, Javed, James B. Young, William T. Abraham, Robert C. Bourge, Kirkwood F. Adams, Robert Clare, Christopher O’Connor, and Christopher ESCAPE Investigators. “Beta-blocker use and outcomes among hospitalized heart failure patients.” J Am Coll Cardiol 47, no. 12 (June 20, 2006): 2462–69. https://doi.org/10.1016/j.jacc.2006.03.030.
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• Harrington, R. A., C. M. O’Connor, J. H. Stein, and M. R. Wolff. “An Introduction.” Journal of the American College of Cardiology 47, no. 11 SUPPL. (June 6, 2006). https://doi.org/10.1016/j.jacc.2006.04.027.
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• Packer, Milton, William T. Abraham, Mandeep R. Mehra, Clyde W. Yancy, Christine E. Lawless, Judith E. Mitchell, Frank W. Smart, et al. “Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failure.” J Am Coll Cardiol 47, no. 11 (June 6, 2006): 2245–52. https://doi.org/10.1016/j.jacc.2005.12.071.
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• Wagoner, Lynne E., Randall C. Starling, and Christopher M. O’Connor. “Cardiac function and heart failure.” J Am Coll Cardiol 47, no. 11 Suppl (June 6, 2006): D18–22. https://doi.org/10.1016/j.jacc.2006.04.041.
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• Cohn, Jay N., Peter E. Carson, Christopher O’Connor, Cristina Opasich, Ileana L. Piña, Marino Scherillo, Gianfranco Sinagra, Lynne Warner-Stevenson, Felix E. Tristani, and Alberto Volpi. “Prognosis and mechanism of death in treated heart failure: data from the placebo arm of Val-HeFT.” Congest Heart Fail 12, no. 3 (May 2006): 127–31. https://doi.org/10.1111/j.1527-5299.2006.05441.x.
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• Stevenson, L. W., C. M. O’Connor, and R. M. Califf. “In reply [2].” Journal of the American Medical Association 295, no. 10 (March 8, 2006): 1121–22. https://doi.org/10.1001/jama.295.10.1121-b.
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• Davidson, Robert M., J Frederick McNeer, Leanne Logan, Michael B. Higginbotham, Jerome Anderson, Joseph Blackshear, Alan Chu, et al. “A cooperative network of trained sites for the conduct of a complex clinical trial: a new concept in multicenter clinical research.” Am Heart J 151, no. 2 (February 2006): 451–56. https://doi.org/10.1016/j.ahj.2005.04.013.
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• Felker, G Michael, Linda K. Shaw, Wendy Gattis Stough, and Christopher M. O’Connor. “Anemia in patients with heart failure and preserved systolic function.” Am Heart J 151, no. 2 (February 2006): 457–62. https://doi.org/10.1016/j.ahj.2005.03.056.
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• Douglas, Pamela, Robert A. Harrington, Christopher M. O’Connor, James H. Stein, and Matthew R. Wolff. “President's page: New York 1952 to Atlanta 2006: celebrating the cardiovascular community.” J Am Coll Cardiol 47, no. 1 (January 3, 2006): 203–4. https://doi.org/10.1016/j.jacc.2005.11.008.
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• Doraiswamy, P Murali, Indira Varia, Caroline Hellegers, H Ryan Wagner, Greg L. Clary, John L. Beyer, L Kristin Newby, et al. “A randomized controlled trial of paroxetine for noncardiac chest pain.” Psychopharmacol Bull 39, no. 1 (2006): 15–24.
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• Felker, G Michael, Wendy Gattis Stough, Linda K. Shaw, and Christopher M. O’Connor. “Anaemia and coronary artery disease severity in patients with heart failure.” Eur J Heart Fail 8, no. 1 (January 2006): 54–57. https://doi.org/10.1016/j.ejheart.2005.05.004.
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• Serebruany, Victor L., Alex N. Pokov, Alex I. Malinin, Christopher O’Connor, Deepak L. Bhatt, Jean-Francois Tanguay, David C. Sane, and Charles H. Hennekens. “Valsartan inhibits platelet activity at different doses in mild to moderate hypertensives: Valsartan Inhibits Platelets (VIP) trial.” Am Heart J 151, no. 1 (January 2006): 92–99. https://doi.org/10.1016/j.ahj.2005.03.001.
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• Carson, Peter, Inder Anand, Christopher O’Connor, Brian Jaski, Jonathan Steinberg, Amy Lwin, JoAnn Lindenfeld, et al. “Mode of death in advanced heart failure: the Comparison of Medical, Pacing, and Defibrillation Therapies in Heart Failure (COMPANION) trial.” J Am Coll Cardiol 46, no. 12 (December 20, 2005): 2329–34. https://doi.org/10.1016/j.jacc.2005.09.016.
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• Shah, Monica R., Karen A. Claise, Margaret T. Bowers, Manjushri Bhapkar, Julie Little, Anju Nohria, Laura H. Gaulden, et al. “Testing new targets of therapy in advanced heart failure: the design and rationale of the Strategies for Tailoring Advanced Heart Failure Regimens in the Outpatient Setting: BRain NatrIuretic Peptide Versus the Clinical CongesTion ScorE (STARBRITE) trial.” Am Heart J 150, no. 5 (November 2005): 893–98. https://doi.org/10.1016/j.ahj.2005.01.003.
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• Hernandez, Adrian F., Eric J. Velazquez, Scott D. Solomon, Rakhi Kilaru, Rafael Diaz, Christopher M. O’Connor, George Ertl, et al. “Left ventricular assessment in myocardial infarction: the VALIANT registry.” Arch Intern Med 165, no. 18 (October 10, 2005): 2162–69. https://doi.org/10.1001/archinte.165.18.2162.
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• Shah, Monica R., Vic Hasselblad, Lynne W. Stevenson, Cynthia Binanay, Christopher M. O’Connor, George Sopko, and Robert M. Califf. “Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials.” Jama 294, no. 13 (October 5, 2005): 1664–70. https://doi.org/10.1001/jama.294.13.1664.
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• Binanay, C., R. M. Califf, V. Hasselblad, C. M. O’Connor, M. R. Shah, G. Sopko, L. W. Stevenson, et al. “Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial.” Jama : The Journal of the American Medical Association 294, no. 13 (October 2005): 1625–33.
• Thomas, Kevin L., Mark A. East, Eric J. Velazquez, Robert H. Tuttle, Linda K. Shaw, Christopher M. O’Connor, and Eric D. Peterson. “Outcomes by race and etiology of patients with left ventricular systolic dysfunction.” Am J Cardiol 96, no. 7 (October 1, 2005): 956–63. https://doi.org/10.1016/j.amjcard.2005.07.002.
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• Gheorghiade, Mihai, Wendy Gattis Stough, Kirkwood F. Adams, Allan S. Jaffe, Victor Hasselblad, and Christopher M. O’Connor. “The Pilot Randomized Study of Nesiritide Versus Dobutamine in Heart Failure (PRESERVD-HF).” Am J Cardiol 96, no. 6A (September 19, 2005): 18G-25G. https://doi.org/10.1016/j.amjcard.2005.07.017.
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• Stough, Wendy Gattis, Christopher M. O’Connor, and Mihai Gheorghiade. “Overview of current noninodilator therapies for acute heart failure syndromes.” Am J Cardiol 96, no. 6A (September 19, 2005): 41G-46G. https://doi.org/10.1016/j.amjcard.2005.07.020.
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• Harrington, R. A., R. C. Becker, M. Ezekowttz, T. W. Meade, C. C. O’Connor, D. A. Vorchheimer, G. H. Guyatt, et al. “VII. Anticoagulant treatment of coronary disease.” Journal Des Maladies Vasculaires 30, no. SPEC. ISS. 2 (September 1, 2005).
• Serebruany, Victor L., Christopher M. O’Connor, Ranga R. Krishnan, and Charles H. Hennekens. “Hypothesis: antiplatelet effects of selective serotonin reuptake inhibitors cause clinical benefits on cardiovascular disease and increase risks of bleeding.” J Cardiovasc Pharmacol Ther 10, no. 3 (September 2005): 163–64. https://doi.org/10.1177/107424840501000303.
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• Schroder, Jacob N., Matthew L. Williams, Jonathan A. Hata, Lawrence H. Muhlbaier, Madhav Swaminathan, Joseph P. Mathew, Donald D. Glower, Christopher M. O’Connor, Peter K. Smith, and Carmelo A. Milano. “Impact of mitral valve regurgitation evaluated by intraoperative transesophageal echocardiography on long-term outcomes after coronary artery bypass grafting.” Circulation 112, no. 9 Suppl (August 30, 2005): I293–98. https://doi.org/10.1161/CIRCULATIONAHA.104.523472.
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• Adams, Kirkwood F., J Herbert Patterson, Wendy A. Gattis, Christopher M. O’Connor, Craig R. Lee, Todd A. Schwartz, and Mihai Gheorghiade. “Relationship of serum digoxin concentration to mortality and morbidity in women in the digitalis investigation group trial: a retrospective analysis.” J Am Coll Cardiol 46, no. 3 (August 2, 2005): 497–504. https://doi.org/10.1016/j.jacc.2005.02.091.
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• Evans, Dwight L., Dennis S. Charney, Lydia Lewis, Robert N. Golden, Jack M. Gorman, K Ranga Rama Krishnan, Charles B. Nemeroff, et al. “Mood disorders in the medically ill: scientific review and recommendations.” Biol Psychiatry 58, no. 3 (August 1, 2005): 175–89. https://doi.org/10.1016/j.biopsych.2005.05.001.
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• Jiang, Wei, Alexander Glassman, Ranga Krishnan, Christopher M. O’Connor, and Robert M. Califf. “Depression and ischemic heart disease: what have we learned so far and what must we do in the future?” Am Heart J 150, no. 1 (July 2005): 54–78. https://doi.org/10.1016/j.ahj.2005.04.012.
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• Teerlink, John R., John J. V. McMurray, Robert C. Bourge, John G. F. Cleland, Gadi Cotter, Guillaume Jondeau, Henry Krum, et al. “Tezosentan in patients with acute heart failure: design of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Study (VERITAS).” Am Heart J 150, no. 1 (July 2005): 46–53. https://doi.org/10.1016/j.ahj.2005.04.035.
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• Serebruany, Victor L., Raymond F. Suckow, Thomas B. Cooper, Christopher M. O’Connor, Alex I. Malinin, K Ranga R. Krishnan, Louis T. van Zyl, Vladimir Lekht, Alexander H. Glassman, and Alexander H. Sertraline Antidepressant Heart Attack Randomized Trial. “Relationship between release of platelet/endothelial biomarkers and plasma levels of sertraline and N-desmethylsertraline in acute coronary syndrome patients receiving SSRI treatment for depression.” Am J Psychiatry 162, no. 6 (June 2005): 1165–70. https://doi.org/10.1176/appi.ajp.162.6.1165.
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• Klein, Liviu, Christopher M. O’Connor, Jeffrey D. Leimberger, Wendy Gattis-Stough, Ileana L. Piña, G Michael Felker, Kirkwood F. Adams, Robert M. Califf, Mihai Gheorghiade, and Mihai OPTIME-CHF Investigators. “Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study.” Circulation 111, no. 19 (May 17, 2005): 2454–60. https://doi.org/10.1161/01.CIR.0000165065.82609.3D.
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• Kovacic, Jason C. “Further aspects of anemia, heart failure, and erythropoietin.” J Am Coll Cardiol 45, no. 9 (May 3, 2005): 1549–50. https://doi.org/10.1016/j.jacc.2005.02.023.
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• Joynt, Karen E., and Christopher M. O’Connor. “Lessons from SADHART, ENRICHD, and other trials.” Psychosom Med 67 Suppl 1 (May 2005): S63–66. https://doi.org/10.1097/01.psy.0000163454.25036.fc.
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• Al-Khatib, Sana M., Kevin J. Anstrom, Eric L. Eisenstein, Eric D. Peterson, James G. Jollis, Daniel B. Mark, Yun Li, Christopher M. O’Connor, Linda K. Shaw, and Robert M. Califf. “Clinical and economic implications of the Multicenter Automatic Defibrillator Implantation Trial-II.” Ann Intern Med 142, no. 8 (April 19, 2005): 593–600. https://doi.org/10.7326/0003-4819-142-8-200504190-00007.
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• O’Connor, Christopher M., Wendy Gattis Stough, Dianne S. Gallup, Vic Hasselblad, and Mihai Gheorghiade. “Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry.” J Card Fail 11, no. 3 (April 2005): 200–205. https://doi.org/10.1016/j.cardfail.2004.08.160.
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• Whellan, David J., Vic Hasselblad, Eric Peterson, Christopher M. O’Connor, and Kevin A. Schulman. “Metaanalysis and review of heart failure disease management randomized controlled clinical trials.” Am Heart J 149, no. 4 (April 2005): 722–29. https://doi.org/10.1016/j.ahj.2004.09.023.
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• O’Connor, Christopher M., Alexander H. Glassman, and David J. Harrison. “Pharmacoeconomic analysis of sertraline treatment of depression in patients with unstable angina or a recent myocardial infarction.” J Clin Psychiatry 66, no. 3 (March 2005): 346–52. https://doi.org/10.4088/jcp.v66n0311.
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• Felker, G Michael, Jeffrey D. Leimberger, Robert M. Califf, Michael S. Cuffe, Barry M. Massie, Kirkwood F. Adams, Mihai Gheorghiade, and Christopher M. O’Connor. “Risk stratification after hospitalization for decompensated heart failure.” J Card Fail 10, no. 6 (December 2004): 460–66. https://doi.org/10.1016/j.cardfail.2004.02.011.
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• Jiang, Wei, Maragatha Kuchibhatla, Michael S. Cuffe, Eric J. Christopher, Jude D. Alexander, Greg L. Clary, Michael A. Blazing, et al. “Prognostic value of anxiety and depression in patients with chronic heart failure.” Circulation 110, no. 22 (November 30, 2004): 3452–56. https://doi.org/10.1161/01.CIR.0000148138.25157.F9.
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• Velazquez, Eric J., Gary S. Francis, Paul W. Armstrong, Phillip E. Aylward, Rafael Diaz, Christopher M. O’Connor, Harvey D. White, et al. “An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry.” Eur Heart J 25, no. 21 (November 2004): 1911–19. https://doi.org/10.1016/j.ehj.2004.08.006.
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• Serebruany, Victor L., Mark G. Midei, Alex I. Malinin, Benjamin R. Oshrine, David R. Lowry, David C. Sane, Jean-François Tanguay, et al. “Absence of interaction between atorvastatin or other statins and clopidogrel: results from the interaction study.” Arch Intern Med 164, no. 18 (October 11, 2004): 2051–57. https://doi.org/10.1001/archinte.164.18.2051.
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• Hernandez, Adrian F., David J. Whellan, Sharon Stroud, Jie Lena Sun, Christopher M. O’Connor, and James G. Jollis. “Outcomes in heart failure patients after major noncardiac surgery.” J Am Coll Cardiol 44, no. 7 (October 6, 2004): 1446–53. https://doi.org/10.1016/j.jacc.2004.06.059.
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• Swenson, J Robert, Christopher M. O’Connor, David Barton, Louis T. Van Zyl, Karl Swedberg, Leslie M. Forman, Michael Gaffney, Alexander H. Glassman, and Alexander H. Sertraline Antidepressant Heart Attack Randomized Trial (SADHART) Group. “Influence of depression and effect of treatment with sertraline on quality of life after hospitalization for acute coronary syndrome.” Am J Cardiol 92, no. 11 (December 1, 2003): 1271–76. https://doi.org/10.1016/j.amjcard.2003.08.006.
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• Klein, Liviu, Christopher M. O’Connor, Wendy A. Gattis, Manuela Zampino, Leonardo de Luca, Antonio Vitarelli, Francesco Fedele, and Mihai Gheorghiade. “Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations.” Am J Cardiol 91, no. 9A (May 8, 2003): 18F-40F. https://doi.org/10.1016/s0002-9149(02)03336-2.
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• Bourque, Jamieson MacDonald, Eric J. Velazquez, Salvador Borges-Neto, Linda K. Shaw, David J. Whellan, and Christopher M. O’Connor. “Radionuclide viability testing: should it affect treatment strategy in patients with cardiomyopathy and significant coronary artery disease?” Am Heart J 145, no. 5 (May 2003): 758–67. https://doi.org/10.1016/S0002-8703(02)94818-0.
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• Felker, G Michael, Raymond L. Benza, A Bleakley Chandler, Jeffrey D. Leimberger, Michael S. Cuffe, Robert M. Califf, Mihai Gheorghiade, Christopher M. O’Connor, and Christopher M. OPTIME-CHF Investigators. “Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study.” J Am Coll Cardiol 41, no. 6 (March 19, 2003): 997–1003. https://doi.org/10.1016/s0735-1097(02)02968-6.
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• Gheorghiade, Mihai, Wendy A. Gattis, Alejandro Barbagelata, Kirkwood F. Adams, Uri Elkayam, Cesare Orlandi, Christopher M. O’Connor, and Christopher M. Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Congestive Heart Failure Investigators. “Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure.” Am Heart J 145, no. 2 Suppl (February 2003): S51–54. https://doi.org/10.1067/mhj.2003.154.
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• Gheorghiade, Mihai, Wendy A. Gattis, Kirkwood F. Adams, Alan S. Jaffe, Christopher M. O’Connor, Christopher M. Pilot Randomized Study of Nesiritide versus Dobutamine in Heart Failure, and Christopher M. Duke University Cooperative Cardiovascular Studies Investigators. “Rationale and design of the pilot randomized study of nesiritide versus dobutamine in heart failure (PRESERVD-HF).” Am Heart J 145, no. 2 Suppl (February 2003): S55–57. https://doi.org/10.1067/mhj.2003.155.
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• Gheorghiade, Mihai, Wendy A. Gattis, Mary Ann Lukas, Christopher M. O’Connor, and Christopher M. Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure Investigators. “Rationale and design of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) study.” Am Heart J 145, no. 2 Suppl (February 2003): S60–61. https://doi.org/10.1067/mhj.2003.157.
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• O’Connor, Christopher M., Wendy A. Gattis, Kirkwood F. Adams, Monica R. Shah, Aline Frey, Mihai Gheorghiade, and Mihai Randomized Intravenous Tezosentan Study Investigators. “Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the fourth Randomized Intravenous Tezosentan Study (RITZ-4).” Am Heart J 145, no. 2 Suppl (February 2003): S58–59. https://doi.org/10.1067/mhj.2003.156.
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• Zampino, Manuela, Christopher M. O’Connor, Wendy A. Gattis, Kirkwood F. Adams, and Mihai Gheorghiade. “Concomitant use of a positive inotropic agent to create a bridge to the successful initiation of beta-blocker therapy in patients with heart failure: a proposal for a trial.” Am Heart J 145, no. 2 Suppl (February 2003): S62–66. https://doi.org/10.1067/mhj.2003.158.
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• Glassman, Alexander H., Christopher M. O’Connor, Robert M. Califf, Karl Swedberg, Peter Schwartz, J Thomas Bigger, K Ranga Rama Krishnan, et al. “Sertraline treatment of major depression in patients with acute MI or unstable angina.” Jama 288, no. 6 (August 14, 2002): 701–9. https://doi.org/10.1001/jama.288.6.701.
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• Gurbel, Paul A., Alex I. Malinin, Kevin P. Callahan, Victor L. Serebruany, and Christopher M. O’Connor. “Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation.” Am J Cardiol 90, no. 3 (August 1, 2002): 312–15. https://doi.org/10.1016/s0002-9149(02)02471-2.
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• Serebruany, V., M. McKenzie, A. Meister, S. Fuzaylov, P. Gurbel, D. Atar, W. Gattis, and C. O’Connor. “Whole blood impedance aggregometry for the assessment of platelet function in patients with congestive heart failure (EPCOT Trial).” Eur J Heart Fail 4, no. 4 (August 2002): 461–67. https://doi.org/10.1016/s1388-9842(02)00026-0.
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• O’Connor, Christopher M., Eric J. Velazquez, Laura H. Gardner, Peter K. Smith, Mark F. Newman, Kevin P. Landolfo, Kerry L. Lee, Robert M. Califf, and Robert H. Jones. “Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank).” Am J Cardiol 90, no. 2 (July 15, 2002): 101–7. https://doi.org/10.1016/s0002-9149(02)02429-3.
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• Neuberg, Gerald W., Alan B. Miller, Chris M. O’Connor, Robert N. Belkin, Peter E. Carson, Anne B. Cropp, David J. Frid, et al. “Diuretic resistance predicts mortality in patients with advanced heart failure.” Am Heart J 144, no. 1 (July 2002): 31–38. https://doi.org/10.1067/mhj.2002.123144.
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• Whellan, David J., and Christopher M. O’Connor. “The state of exercise training: a need for action.” Am Heart J 144, no. 1 (July 2002): 1–4. https://doi.org/10.1067/mhj.2002.123311.
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• Gottlieb, Stephen S., William Abraham, Javed Butler, Daniel E. Forman, Evan Loh, Barry M. Massie, Christopher M. O’connor, et al. “The prognostic importance of different definitions of worsening renal function in congestive heart failure.” J Card Fail 8, no. 3 (June 2002): 136–41. https://doi.org/10.1054/jcaf.2002.125289.
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• Gurbel, Paul A., Wendy A. Gattis, Sergey F. Fuzaylov, Laura Gaulden, Vic Hasselblad, Victor L. Serebruany, and Christopher M. O’Connor. “Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?” Am Heart J 143, no. 6 (June 2002): 1068–75. https://doi.org/10.1067/mhj.2002.121261.
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• Shah, Monica R., Vic Hasselblad, Sandra S. Stinnett, Judith M. Kramer, Steven Grossman, Mihai Gheorghiade, Kirkwood F. Adams, Karl Swedberg, Robert M. Califf, and Christopher M. O’Connor. “Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure.” Eur J Heart Fail 4, no. 3 (June 2002): 297–304. https://doi.org/10.1016/s1388-9842(01)00202-1.
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• Cuffe, Michael S., Robert M. Califf, Kirkwood F. Adams, Raymond Benza, Robert Bourge, Wilson S. Colucci, Barry M. Massie, et al. “Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial.” Jama 287, no. 12 (March 27, 2002): 1541–47. https://doi.org/10.1001/jama.287.12.1541.
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• Jiang, Wei, Vic Hasselblad, Ranga R. Krishnan, and Christopher M. O’Connor. “Patients with CHF and depression have greater risk of mortality and morbidity than patients without depression.” J Am Coll Cardiol 39, no. 5 (March 6, 2002): 919–21. https://doi.org/10.1016/s0735-1097(02)01694-7.
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• Rozzini, Renzo, Tony Sabatini, Giovanni B. Frisoni, and Marco Trabucchi. “Depression and major outcomes in older patients with heart failure.” Arch Intern Med 162, no. 3 (February 11, 2002): 362–64. https://doi.org/10.1001/archinte.162.3.362-a.
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• Felker, G Michael, Linda K. Shaw, and Christopher M. O’Connor. “A standardized definition of ischemic cardiomyopathy for use in clinical research.” J Am Coll Cardiol 39, no. 2 (January 16, 2002): 210–18. https://doi.org/10.1016/s0735-1097(01)01738-7.
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• Blumenthal, James A., Michael Babyak, Jiang Wei, Christopher O’Connor, Robert Waugh, Eric Eisenstein, Daniel Mark, et al. “Usefulness of psychosocial treatment of mental stress-induced myocardial ischemia in men.” Am J Cardiol 89, no. 2 (January 15, 2002): 164–68. https://doi.org/10.1016/s0002-9149(01)02194-4.
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• Cuffe, M., R. Califf, K. Adams, R. Benza, R. Bourge, W. Colucci, B. Massie, et al. “Intravenous milrinone is no better than standard therapy for people admitted with acute exacerbation of chronic heart failure.” Evidence Based Cardiovascular Medicine 6, no. 4 (January 1, 2002): 154–55. https://doi.org/10.1054/ebcm.2002.0490.
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• Jiang, Wei, Ranga R. K. Krishnan, and Christopher M. O’Connor. “Depression and heart disease: evidence of a link, and its therapeutic implications.” Cns Drugs 16, no. 2 (2002): 111–27. https://doi.org/10.2165/00023210-200216020-00004.
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• Serebruany, Victor L., Marcus E. McKenzie, Andrew F. Meister, Sergey Y. Fuzaylov, Paul A. Gurbel, Dan Atar, Wendy A. Gattis, and Christopher M. O’Connor. “Failure of platelet parameters and biomarkers to correlate platelet function to severity and etiology of heart failure in patients enrolled in the EPCOT trial. With special reference to the Hemodyne hemostatic analyzer. Whole Blood Impedance Aggregometry for the Assessment of Platelet Function in Patients with Congestive Heart Failure.” Pathophysiol Haemost Thromb 32, no. 1 (January 2002): 8–15. https://doi.org/10.1159/000057283.
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• Shah, Bimal R., Eric Velazquez, Linda K. Shaw, Brad Bart, Christopher O’Connor, and Galen S. Wagner. “Revascularization improves survival in ischemic cardiomyopathy regardless of electrocardiographic criteria for prior small-to-medium myocardial infarcts.” Am Heart J 143, no. 1 (January 2002): 111–17. https://doi.org/10.1067/mhj.2002.119996.
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• Gattis, Wendy A., Christopher M. O’Connor, and Mihai Gheorghiade. “The Initiation Management Predischarge Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) Study: design and implications.” Rev Cardiovasc Med 3 Suppl 3 (2002): S48–54.
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• Gheorghiade, Mihai, Wendy A. Gattis, and Christopher M. O’Connor. “Treatment gaps in the pharmacologic management of heart failure.” Rev Cardiovasc Med 3 Suppl 3 (2002): S11–19.
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• Felker, G. M., and C. M. O’connor. “Between Scylla and Charybdis: The choice of inotropic agent for decompensated heart failure.” Am Heart J 142, no. 6 (December 2001): 932–33. https://doi.org/10.1067/mhj.2001.119611.
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• Serebruany, V. L., C. J. Davis, A. F. Meister, D. Atar, D. J. Whellan, and C. M. O’Connor. “Biomarkers and exercise training: A possible missing link between physical activity and mortality benefit in patients with heart failure.” Heartdrug 1, no. 2 (December 1, 2001): 110–24. https://doi.org/10.1159/000048946.
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• Shah, M. R., V. Hasselblad, M. Gheorghiade, K. F. Adams, K. Swedberg, R. M. Califf, and C. M. O’Connor. “Prognostic usefulness of the six-minute walk in patients with advanced congestive heart failure secondary to ischemic or nonischemic cardiomyopathy.” Am J Cardiol 88, no. 9 (November 1, 2001): 987–93. https://doi.org/10.1016/s0002-9149(01)01975-0.
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• Carney, R. M., J. A. Blumenthal, P. K. Stein, L. Watkins, D. Catellier, L. F. Berkman, S. M. Czajkowski, C. O’Connor, P. H. Stone, and K. E. Freedland. “Depression, heart rate variability, and acute myocardial infarction.” Circulation 104, no. 17 (October 23, 2001): 2024–28. https://doi.org/10.1161/hc4201.097834.
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• Whellan, D. J., L. Gaulden, W. A. Gattis, B. Granger, S. D. Russell, M. A. Blazing, M. S. Cuffe, and C. M. O’Connor. “The benefit of implementing a heart failure disease management program.” Arch Intern Med 161, no. 18 (October 8, 2001): 2223–28. https://doi.org/10.1001/archinte.161.18.2223.
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• Felker, G. M., and C. M. O’Connor. “Inotropic therapy for heart failure: an evidence-based approach.” Am Heart J 142, no. 3 (September 2001): 393–401. https://doi.org/10.1067/mhj.2001.117606.
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• O’Connor, C. M., W. A. Gattis, A. S. Hellkamp, A. Langer, R. L. Larsen, R. A. Harrington, S. D. Berkowitz, et al. “Comparison of two aspirin doses on ischemic stroke in post-myocardial infarction patients in the warfarin (Coumadin) Aspirin Reinfarction Study (CARS).” Am J Cardiol 88, no. 5 (September 1, 2001): 541–46. https://doi.org/10.1016/s0002-9149(01)01735-0.
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• ENRICHD Investigators, E. N. R. I. C. H. D. “Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design.” Psychosom Med 63, no. 5 (September 2001): 747–55.
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• ENRICHD Investigators, J. M. “Enhancing recovery in coronary heart disease (ENRICHD): baseline characteristics.” Am J Cardiol 88, no. 3 (August 1, 2001): 316–22. https://doi.org/10.1016/s0002-9149(01)01652-6.
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• Jiang, W., J. Alexander, E. Christopher, M. Kuchibhatla, L. H. Gaulden, M. S. Cuffe, M. A. Blazing, et al. “Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure.” Archives of Internal Medicine 161, no. 15 (August 2001): 1849–56. https://doi.org/10.1001/archinte.161.15.1849.
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• Alexander, K. P., L. K. Newby, A. S. Hellkamp, R. A. Harrington, E. D. Peterson, S. Kopecky, A. Langer, et al. “Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up.” J Am Coll Cardiol 38, no. 1 (July 2001): 1–7. https://doi.org/10.1016/s0735-1097(01)01329-8.
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• Whellan, D. J., L. K. Shaw, B. A. Bart, W. E. Kraus, R. M. Califf, and C. M. O’Connor. “Cardiac rehabilitation and survival in patients with left ventricular systolic dysfunction.” Am Heart J 142, no. 1 (July 2001): 160–66. https://doi.org/10.1067/mhj.2001.115785.
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• Serebruany, V. L., C. M. O’Connor, and P. A. Gurbel. “Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease.” Am J Cardiol 87, no. 12 (June 15, 2001): 1398–1400. https://doi.org/10.1016/s0002-9149(01)01562-4.
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• Rosenberg, E. L., P. Ekman, W. Jiang, M. Babyak, R. E. Coleman, M. Hanson, C. O’Connor, R. Waugh, and J. A. Blumenthal. “Linkages between facial expressions of anger and transient myocardial ischemia in men with coronary artery disease.” Emotion 1, no. 2 (June 2001): 107–15. https://doi.org/10.1037/1528-3542.1.2.107.
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• Shah, M. R., S. S. Stinnett, S. E. McNulty, M. Gheorghiade, F. Zannad, B. Uretsky, K. F. Adams, R. M. Califf, and C. M. O’connor. “Hemodynamics as surrogate end points for survival in advanced heart failure: an analysis from FIRST.” Am Heart J 141, no. 6 (June 2001): 908–14. https://doi.org/10.1067/mhj.2001.115299.
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• Shah, M. R., V. Hasselblad, S. S. Stinnett, M. Gheorghiade, K. Swedberg, R. M. Califf, and C. M. O’Connor. “Hemodynamic profiles of advanced heart failure: association with clinical characteristics and long-term outcomes.” J Card Fail 7, no. 2 (June 2001): 105–13. https://doi.org/10.1054/jcaf.2001.24131.
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• Serebruany, V. L., P. A. Gurbel, and C. M. O’Connor. “Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors.” Pharmacol Res 43, no. 5 (May 2001): 453–62. https://doi.org/10.1006/phrs.2001.0817.
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• Shah, M. R., C. M. O’Connor, G. Sopko, V. Hasselblad, R. M. Califf, and L. W. Stevenson. “Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE): design and rationale.” Am Heart J 141, no. 4 (April 2001): 528–35. https://doi.org/10.1067/mhj.2001.113995.
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• Gurbel, P. A., C. M. O’Connor, M. R. Dalesandro, and V. L. Serebruany. “Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy.” Am J Cardiol 87, no. 6 (March 15, 2001): 774-A7. https://doi.org/10.1016/s0002-9149(00)01502-2.
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• Serebruany, V. L., A. B. Alford, A. F. Meister, S. Y. Fuzaylov, W. A. Gattis, P. A. Gurbel, and C. M. O’Connor. “Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial).” Thromb Res 101, no. 6 (March 15, 2001): 427–33. https://doi.org/10.1016/s0049-3848(00)00431-x.
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• Gattis, W. A., and C. M. O’Connor. “Effect of amlodipine on mode of death in advanced heart failure.” Cardiology Review 18, no. 2 (March 12, 2001): 13–19.
• Felker, G. M., and C. M. O’Connor. “Rational use of inotropic therapy in heart failure.” Curr Cardiol Rep 3, no. 2 (March 2001): 108–13. https://doi.org/10.1007/s11886-001-0035-8.
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• Gattis, W. A., A. Galanos, and C. M. O’Connor. “Angiotensin-converting enzyme inhibitor dosing in heart failure: what is optimal?” Am Heart J 141, no. 3 (March 2001): 331–33. https://doi.org/10.1067/mhj.2001.113228.
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• Shah, M. R., and C. M. O’connor. “The congestion score: a simple tool for a complicated disease?” Am Heart J 140, no. 6 (December 2000): 824–26. https://doi.org/10.1067/mhj.2000.110932.
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• O’Connor, C. M., W. A. Gattis, L. Shaw, M. S. Cuffe, and R. M. Califf. “Clinical characteristics and long-term outcomes of patients with heart failure and preserved systolic function.” Am J Cardiol 86, no. 8 (October 15, 2000): 863–67. https://doi.org/10.1016/s0002-9149(00)01107-3.
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• Nemeroff, C. B., and C. M. O’connor. “Introduction.” Am Heart J 140, no. 4 Suppl (October 2000): 55–56. https://doi.org/10.1067/mhj.2000.109976.
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• O’connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Depression and ischemic heart disease.” Am Heart J 140, no. 4 Suppl (October 2000): 63–69. https://doi.org/10.1067/mhj.2000.109979.
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• Varia, I., E. Logue, C. O’connor, K. Newby, H. R. Wagner, C. Davenport, K. Rathey, and K. R. Krishnan. “Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin.” Am Heart J 140, no. 3 (September 2000): 367–72. https://doi.org/10.1067/mhj.2000.108514.
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• Carson, P. A., C. M. O’Connor, A. B. Miller, S. Anderson, R. Belkin, G. W. Neuberg, J. H. Wertheimer, D. Frid, A. Cropp, and M. Packer. “Circadian rhythm and sudden death in heart failure: results from Prospective Randomized Amlodipine Survival Trial.” J Am Coll Cardiol 36, no. 2 (August 2000): 541–46. https://doi.org/10.1016/s0735-1097(00)00728-2.
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• Davis, C. J., P. A. Gurbel, W. A. Gattis, S. Y. Fuzaylov, G. V. Nair, C. M. O’Connor, and V. L. Serebruany. “Hemostatic abnormalities in patients with congestive heart failure: diagnostic significance and clinical challenge.” Int J Cardiol 75, no. 1 (August 2000): 15–21. https://doi.org/10.1016/s0167-5273(00)00300-4.
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• Kong, D. F., M. A. Blazing, and C. M. O’Connor. “Advances in the approach to acute coronary syndromes.” Hosp Pract (1995) 35, no. 4 (April 15, 2000): 61–64. https://doi.org/10.3810/hp.2000.04.192.
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• O’Connor, C. M., W. A. Gattis, and T. J. Ryan. “The role of clinical nonfatal end points in cardiovascular phase II/III clinical trials.” Am Heart J 139, no. 4 (April 2000): S143–54. https://doi.org/10.1016/s0002-8703(00)90062-0.
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• Serebruany, V. L., D. R. Lowry, S. Y. Fuzailov, D. J. Levine, C. M. O’Connor, and P. A. Gurbel. “Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction.” J Thromb Thrombolysis 9, no. 3 (April 2000): 229–34. https://doi.org/10.1023/a:1018762510842.
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• Califf, R. M., and C. M. O’Connor. “Beta-blocker therapy for heart failure: the evidence is in, now the work begins.” Jama 283, no. 10 (March 8, 2000): 1335–37. https://doi.org/10.1001/jama.283.10.1335.
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• Shah, A., G. S. Wagner, C. B. Granger, C. M. O’Connor, C. L. Green, K. M. Trollinger, R. M. Califf, and M. W. Krucoff. “Prognostic implications of TIMI flow grade in the infarct related artery compared with continuous 12-lead ST-segment resolution analysis. Reexamining the "gold standard" for myocardial reperfusion assessment.” J Am Coll Cardiol 35, no. 3 (March 1, 2000): 666–72. https://doi.org/10.1016/s0735-1097(99)00601-4.
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• Gurbel, P. A., D. J. Kereiakes, M. R. Dalesandro, R. D. Bahr, C. M. O’Connor, and V. L. Serebruany. “Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.” Am Heart J 139, no. 2 Pt 1 (February 2000): 320–28. https://doi.org/10.1067/mhj.2000.101109.
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• Bosworth, H. B., D. C. Steffens, M. N. Kuchibhatla, W. J. Jiang, R. M. Arias, C. M. O’Connor, and K. R. R. Krishnan. “The relationship of social support, social networks and negative events with depression in patients with coronary artery disease.” Aging and Mental Health 4, no. 3 (January 1, 2000): 253–58. https://doi.org/10.1080/713649927.
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• Cuffe, M. S., R. M. Califf, K. F. Adams, R. C. Bourge, W. Colucci, B. Massie, C. M. O’Connor, et al. “Rationale and design of the OPTIME CHF trial: outcomes of a prospective trial of intravenous milrinone for exacerbations of chronic heart failure.” Am Heart J 139, no. 1 Pt 1 (January 2000): 15–22. https://doi.org/10.1016/s0002-8703(00)90303-x.
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• Gattis, W., and C. M. O’Connor. “[Calcium antagonists in the treatment of heart failure. Re-evaluation of therapeutic strategies].” Drugs 59 Spec No 2 (2000): 17–24.
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• Gattis, W., and C. M. O’Connor. “Calcium antagonist use in heart failure: A re-evalutaion of treatment options.” Drugs 59, no. SPEC. ISS. 2 (January 1, 2000): 17–24. https://doi.org/10.2165/00003495-200059992-00003.
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• Gurbel, P. A., D. J. Kereiakes, M. R. Dalesandro, R. D. Bahr, C. M. O’Connor, and V. L. Serebruany. “Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.” American Heart Journal 139, no. 2 I (2000): 320–28.
• Fortner, Molly R., Kristine Brown, Indu M. Varia, Kenneth R. Gersing, Christopher O’Connor, and P Murali Doraiswamy. “Effect of Bupropion SR on the Quality of Life of Elderly Depressed Patients With Comorbid Medical Disorders.” Prim Care Companion J Clin Psychiatry 1, no. 6 (December 1999): 174–79. https://doi.org/10.4088/pcc.v01n0601.
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• O’Connor, C. M., W. A. Gattis, M. Gheorghiade, C. B. Granger, J. Gilbert, J. M. McKenney, F. C. Messineo, et al. “A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: the U.S. ecadotril pilot safety study.” Am Heart J 138, no. 6 Pt 1 (December 1999): 1140–48. https://doi.org/10.1016/s0002-8703(99)70081-5.
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• Velazquez, E. J., and C. M. O’Connor. “Heart failure after myocardial infarction: A good heart is hard to find.” Am Heart J 138, no. 6 Pt 1 (December 1999): 1009–11. https://doi.org/10.1016/s0002-8703(99)70061-x.
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• Orloff, D. G., M. A. Blazing, and C. M. O’Connor. “Atherosclerotic disease in non-insulin-dependent diabetes mellitus: role of abnormal lipids and the place for lipid-altering therapies.” Am Heart J 138, no. 5 Pt 1 (November 1999): S406–12. https://doi.org/10.1016/s0002-8703(99)70043-8.
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• Del Carlo, C. H., and C. M. O’Connor. “Cardiac troponins in congestive heart failure.” Am Heart J 138, no. 4 Pt 1 (October 1999): 646–53. https://doi.org/10.1016/s0002-8703(99)70178-x.
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• Doraiswamy, P. M., J. MacFall, K. R. Krishnan, C. O’Connor, X. Wan, M. Benaur, M. Lewandowski, and M. Fortner. “Magnetic resonance assessment of cerebral perfusion in depressed cardiac patients: preliminary findings.” Am J Psychiatry 156, no. 10 (October 1999): 1641–43. https://doi.org/10.1176/ajp.156.10.1641.
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• Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada. The CARS Investigators (Coumadin/Aspirin Reinfarction Study).” Can J Cardiol 15, no. 10 (October 1999): 1095–1102.
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• Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada.” Canadian Journal of Cardiology 15, no. 10 (October 1, 1999): 1095–1102.
• Gattis, W. A., V. Hasselblad, D. J. Whellan, and C. M. O’Connor. “Reduction in heart failure events by the addition of a clinical pharmacist to the heart failure management team: results of the Pharmacist in Heart Failure Assessment Recommendation and Monitoring (PHARM) Study.” Arch Intern Med 159, no. 16 (September 13, 1999): 1939–45. https://doi.org/10.1001/archinte.159.16.1939.
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• Gurbel, P. A., C. M. O’Connor, C. C. Cummings, and V. L. Serebruany. “Clopidogrel: the future choice for preventing platelet activation during coronary stenting?” Pharmacol Res 40, no. 2 (August 1999): 107–11. https://doi.org/10.1006/phrs.1999.0478.
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• Nair, G. V., P. A. Gurbel, C. M. O’Connor, W. A. Gattis, S. R. Murugesan, and V. L. Serebruany. “Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors.” Am J Cardiol 84, no. 3 (August 1, 1999): 321-A8. https://doi.org/10.1016/s0002-9149(99)00284-2.
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• Serebruany, V. L., S. R. Murugesan, A. Pothula, D. Atar, D. R. Lowry, C. M. O’Connor, and P. A. Gurbel. “Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy.” Eur J Heart Fail 1, no. 3 (August 1999): 243–49. https://doi.org/10.1016/s1388-9842(99)00029-x.
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• Blazing, M. A., and C. M. O’Connor. “Evidence supporting secondary prevention strategies.” Curr Opin Cardiol 14, no. 4 (July 1999): 303–9. https://doi.org/10.1097/00001573-199907000-00005.
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• O’Connor, C. M., P. W. Radensky, A. N. Unger, and B. C. Martin. “Hospital use and costs among patients with nonischemic cardiomyopathy in the first prospective randomized amlodipine survival evaluation study.” Clin Ther 21, no. 7 (July 1999): 1254–65. https://doi.org/10.1016/S0149-2918(00)80027-2.
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• O’Connor, C. M., W. A. Gattis, B. F. Uretsky, K. F. Adams, S. E. McNulty, S. H. Grossman, W. J. McKenna, et al. “Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST).” Am Heart J 138, no. 1 Pt 1 (July 1999): 78–86. https://doi.org/10.1016/s0002-8703(99)70250-4.
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• O’Connor, C. M., W. A. Gattis, and K. Swedberg. “Current and novel pharmacologic approaches in advanced heart failure.” Heart Lung 28, no. 4 (July 1999): 227–42. https://doi.org/10.1016/s0147-9563(99)70069-5.
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• Shapiro, P. A., F. Lespérance, N. Frasure-Smith, C. M. O’Connor, B. Baker, J. W. Jiang, P. Dorian, W. Harrison, and A. H. Glassman. “An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT Trial). Sertraline Anti-Depressant Heart Attack Trial.” Am Heart J 137, no. 6 (June 1999): 1100–1106. https://doi.org/10.1016/s0002-8703(99)70369-8.
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• Kong, D. F., M. A. Blazing, and C. M. O’Connor. “The health care burden of unstable angina.” Cardiol Clin 17, no. 2 (May 1999): 247–61. https://doi.org/10.1016/s0733-8651(05)70072-2.
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• O’Connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure.” Am J Cardiol 83, no. 9 (May 1, 1999): 1345–49. https://doi.org/10.1016/s0002-9149(99)00098-3.
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• Adams, K. F., C. A. Sueta, M. Gheorghiade, C. M. O’Connor, T. A. Schwartz, G. G. Koch, B. Uretsky, et al. “Gender differences in survival in advanced heart failure. Insights from the FIRST study.” Circulation 99, no. 14 (April 13, 1999): 1816–21. https://doi.org/10.1161/01.cir.99.14.1816.
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• Whellan, D. J., W. A. Gattis, L. Gaulden, B. Granger, and C. M. O’Connor. “Disease management of congestive heart failure.” Am J Manag Care 5, no. 4 (April 1999): 499–507.
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• O’Connor, C. M., W. A. Gattis, F. Zannad, S. E. McNulty, M. Gheorghiade, K. F. Adams, R. M. Califf, W. J. McKenna, J. Soler-Soler, and K. Swedberg. “Beta-blocker therapy in advanced heart failure: clinical characteristics and long-term outcomes.” Eur J Heart Fail 1, no. 1 (March 1999): 81–88. https://doi.org/10.1016/S1388-9842(98)00004-X.
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• Steffens, D. C., C. M. O’Connor, W. J. Jiang, C. F. Pieper, M. N. Kuchibhatla, R. M. Arias, A. Look, C. Davenport, M. B. Gonzalez, and K. R. Krishnan. “The effect of major depression on functional status in patients with coronary artery disease.” Journal of the American Geriatrics Society 47, no. 3 (March 1999): 319–22. https://doi.org/10.1111/j.1532-5415.1999.tb02995.x.
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• Bart, B. A., and C. M. O’Connor. “Clinical determinants of mortality in patients with cardiomyopathy.” Cardiology Review 16, no. 7 (January 1, 1999): 8–11.
• McKenzie, M. E., A. Pothula, P. A. Gurbel, S. Y. Fuzaylov, C. M. O’Connor, W. A. Gattis, and V. L. Serebruany. “Failure of thrombin generation markers to triage patients presenting with chest pain.” Cardiology 92, no. 1 (1999): 53–58. https://doi.org/10.1159/000006946.
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• Thel, M. C., and C. M. O’Connor. “Cardiopulmonary resuscitation: historical perspective to recent investigations.” Am Heart J 137, no. 1 (January 1999): 39–48. https://doi.org/10.1016/s0002-8703(99)70458-8.
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• O’Connor, C. M., P. E. Carson, A. B. Miller, M. L. Pressler, R. N. Belkin, G. W. Neuberg, D. J. Frid, et al. “Effect of amlodipine on mode of death among patients with advanced heart failure in the PRAISE trial. Prospective Randomized Amlodipine Survival Evaluation.” Am J Cardiol 82, no. 7 (October 1, 1998): 881–87. https://doi.org/10.1016/s0002-9149(98)00496-2.
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• Guyton, J. R., A. C. Goldberg, R. A. Kreisberg, D. L. Sprecher, H. R. Superko, and C. M. O’Connor. “Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia.” Am J Cardiol 82, no. 6 (September 15, 1998): 737–43. https://doi.org/10.1016/s0002-9149(98)00448-2.
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• Krishnan, K. R., L. K. George, C. F. Pieper, W. Jiang, R. Arias, A. Look, and C. O’Connor. “Depression and social support in elderly patients with cardiac disease.” American Heart Journal 136, no. 3 (September 1998): 491–95. https://doi.org/10.1016/s0002-8703(98)70225-x.
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• Shah, B. R., C. Lin, C. Maynard, B. Bart, R. H. Selvester, L. K. Shaw, C. O’Connor, and G. S. Wagner. “Specificity of electrocardiographic myocardial infarction screening criteria in patients with nonischemic cardiomyopathies.” Am Heart J 136, no. 2 (August 1998): 314–19. https://doi.org/10.1053/hj.1998.v136.89909.
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• Gattis, W. A., R. L. Larsen, V. Hasselblad, B. A. Bart, and C. M. O’Connor. “Is optimal angiotensin-converting enzyme inhibitor dosing neglected in elderly patients with heart failure?” Am Heart J 136, no. 1 (July 1998): 43–48. https://doi.org/10.1016/s0002-8703(98)70180-2.
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• Serebruany, V. L., R. D. Bahr, C. M. O’Connor, D. R. Lowry, and P. A. Gurbel. “Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction. The GUSTO-III Platelet Substudy.” Cardiology 90, no. 1 (July 1998): 37–42. https://doi.org/10.1159/000006814.
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• O’Connor, C. M., W. A. Gattis, and K. Swedberg. “Current and novel pharmacologic approaches in advanced heart failure.” Am Heart J 135, no. 6 Pt 2 Su (June 1998): S249–63. https://doi.org/10.1016/s0002-8703(98)70254-6.
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• Serebruany, V. L., D. Atar, M. R. Dalesandro, C. M. O’Connor, and P. A. Gurbel. “Changes in hemostasis after parenteral magnesium in myocardial ischemia-reperfusion: from animal studies to clinical trials.” Magnes Res 11, no. 2 (June 1998): 133–40.
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• Flack, J. M., C. M. O’Connor, and J. Y. Wei. “Four commonly seen cardiovascular diseases.” Patient Care 32, no. 9 (May 15, 1998): 98–130.
• Hassan, T. B., and D. B. Barnett. “Magnesium in in-hospital cardiac arrest.” Lancet 351, no. 9100 (February 7, 1998): 445–46. https://doi.org/10.1016/S0140-6736(05)78390-2.
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• Cuffe, M. S., and C. M. O’Connor. “Pharmacologic management of acute heart failure.” Current Opinion in Critical Care 3, no. 5 (December 1, 1997): 386–90.
• Blumenthal, J. A., C. O’Connor, A. Hinderliter, K. Fath, S. B. Hegde, G. Miller, J. Puma, et al. “Psychosocial factors and coronary disease. A national multicenter clinical trial (ENRICHD) with a North Carolina focus.” N C Med J 58, no. 6 (November 1997): 440–44.
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• Thel, M. C., A. L. Armstrong, S. E. McNulty, R. M. Califf, and C. M. O’Connor. “Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff.” Lancet 350, no. 9087 (November 1, 1997): 1272–76. https://doi.org/10.1016/s0140-6736(97)05048-4.
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• Bart, B. A., L. K. Shaw, C. B. McCants, D. F. Fortin, K. L. Lee, R. M. Califf, and C. M. O’Connor. “Clinical determinants of mortality in patients with angiographically diagnosed ischemic or nonischemic cardiomyopathy.” J Am Coll Cardiol 30, no. 4 (October 1997): 1002–8. https://doi.org/10.1016/s0735-1097(97)00235-0.
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• Blumenthal, J. A., W. Jiang, M. A. Babyak, D. S. Krantz, D. J. Frid, R. E. Coleman, R. Waugh, et al. “Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms.” Archives of Internal Medicine 157, no. 19 (October 1997): 2213–23. https://doi.org/10.1001/archinte.1997.00440400063008.
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• Jiang, W., W. R. Hathaway, S. McNulty, R. L. Larsen, K. L. Hansley, Y. Zhang, and C. M. O’Connor. “Ability of heart rate variability to predict prognosis in patients with advanced congestive heart failure.” Am J Cardiol 80, no. 6 (September 15, 1997): 808–11. https://doi.org/10.1016/s0002-9149(97)00526-2.
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• Hayano, J., W. Jiang, R. Waugh, C. O’Connor, D. Frid, and J. A. Blumenthal. “Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease.” Am Heart J 134, no. 3 (September 1997): 411–18. https://doi.org/10.1016/s0002-8703(97)70075-9.
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• O’Connor, C. M., W. R. Hathaway, E. R. Bates, J. D. Leimberger, K. N. Sigmon, D. J. Kereiakes, B. S. George, et al. “Clinical characteristics and long-term outcome of patients in whom congestive heart failure develops after thrombolytic therapy for acute myocardial infarction: development of a predictive model.” Am Heart J 133, no. 6 (June 1997): 663–73. https://doi.org/10.1016/s0002-8703(97)70168-6.
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• Gullette, E. C., J. A. Blumenthal, M. Babyak, W. Jiang, R. A. Waugh, D. J. Frid, C. M. O’Connor, J. J. Morris, and D. S. Krantz. “Effects of mental stress on myocardial ischemia during daily life.” Jama 277, no. 19 (May 21, 1997): 1521–26.
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• Bart, B. A., W. A. Gattis, S. J. Diem, and C. M. O’Connor. “Reasons for underuse of angiotensin-converting enzyme inhibitors in patients with heart failure and left ventricular dysfunction.” Am J Cardiol 79, no. 8 (April 15, 1997): 1118–20. https://doi.org/10.1016/s0002-9149(97)00060-x.
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• Allan, J. J. “Amlodipine in chronic heart failure.” N Engl J Med 336, no. 14 (April 3, 1997): 1023–24.
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• Packer, M., C. M. O’Connor, J. K. Ghali, M. L. Pressler, P. E. Carson, R. N. Belkin, A. B. Miller, et al. “Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group.” N Engl J Med 335, no. 15 (October 10, 1996): 1107–14. https://doi.org/10.1056/NEJM199610103351504.
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• Barefoot, J. C., M. J. Helms, D. B. Mark, J. A. Blumenthal, R. M. Califf, T. L. Haney, C. M. O’Connor, I. C. Siegler, and R. B. Williams. “Depression and long-term mortality risk in patients with coronary artery disease.” Am J Cardiol 78, no. 6 (September 15, 1996): 613–17. https://doi.org/10.1016/s0002-9149(96)00380-3.
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• Jiang, W., M. Babyak, D. S. Krantz, R. A. Waugh, R. E. Coleman, M. M. Hanson, D. J. Frid, et al. “Mental stress--induced myocardial ischemia and cardiac events.” Jama 275, no. 21 (June 5, 1996): 1651–56. https://doi.org/10.1001/jama.275.21.1651.
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• O’Connor, C. M., R. B. Meese, S. McNulty, K. D. Lucas, R. J. Carney, R. M. LeBoeuf, W. Maddox, et al. “A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction. The DUCCS-II Investigators.” Am J Cardiol 77, no. 10 (April 15, 1996): 791–97. https://doi.org/10.1016/s0002-9149(97)89171-0.
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• Mahaffey, K. W., C. B. Granger, R. Collins, C. M. O’Connor, E. M. Ohman, S. D. Bleich, J. J. Col, and R. M. Califf. “Overview of randomized trials of intravenous heparin in patients with acute myocardial infarction treated with thrombolytic therapy.” Am J Cardiol 77, no. 8 (March 15, 1996): 551–56. https://doi.org/10.1016/s0002-9149(97)89305-8.
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• Gonzalez, M. B., T. B. Snyderman, J. T. Colket, R. M. Arias, J. W. Jiang, C. M. O’Connor, and K. R. Krishnan. “Depression in patients with coronary artery disease.” Depression 4, no. 2 (1996): 57–62. https://doi.org/10.1002/(SICI)1522-7162(1996)4:2<57::AID-DEPR3>3.0.CO;2-C.
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• Jiang, W., M. A. Trauner, R. E. Coleman, R. A. Waugh, M. W. Hanson, D. J. Frid, B. G. Phillips, J. J. Morris, C. O’Connor, and J. A. Blumenthal. “Association of physical fitness and transient myocardial ischemia in patients with coronary artery disease.” J Cardiopulm Rehabil 15, no. 6 (November 1995): 431–38. https://doi.org/10.1097/00008483-199511000-00007.
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• Blumenthal, J. A., W. Jiang, R. A. Waugh, D. J. Frid, J. J. Morris, R. E. Coleman, M. Hanson, M. Babyak, E. T. Thyrum, and D. S. Krantz. “Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life. Association and hemodynamic features.” Circulation 92, no. 8 (October 15, 1995): 2102–8. https://doi.org/10.1161/01.cir.92.8.2102.
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• Thel, M. C., and C. M. O’Connor. “Magnesium in acute myocardial infarction.” Coron Artery Dis 6, no. 10 (October 1995): 831–37. https://doi.org/10.1097/00019501-199510000-00012.
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• Jiang, W., J. A. Blumenthal, M. W. Hanson, R. E. Coleman, C. M. O’Connor, D. Frid, J. J. Morris, and R. A. Waugh. “Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring.” Am J Cardiol 76, no. 5 (August 15, 1995): 350–54. https://doi.org/10.1016/s0002-9149(99)80099-x.
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• Mörike, K., and G. Mikus. “Zofenopril after anterior myocardial infarction.” N Engl J Med 332, no. 25 (June 22, 1995): 1715.
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• Campbell, P. T., J. S. Li, T. C. Wall, C. M. O’Connor, P. Van Trigt, R. T. Kenney, O. Melhus, and G. R. Corey. “Cytomegalovirus pericarditis: a case series and review of the literature.” Am J Med Sci 309, no. 4 (April 1995): 229–34. https://doi.org/10.1097/00000441-199504000-00009.
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• Selker, H. P., J. R. Beshansky, C. H. Schmid, J. L. Griffith, W. T. Longstreth, C. M. O’Connor, L. R. Caplan, E. W. Massey, R. B. D’Agostino, and M. M. Laks. “Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results.” Circulation 90, no. 4 (October 1994): 1657–61. https://doi.org/10.1161/01.cir.90.4.1657.
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• Larsen, R. L., V. S. Behar, S. R. Brazer, J. Chen, and C. M. O’Connor. “Chest pain presenting as ischemic heart disease. Congenital absence of the pericardium.” N C Med J 55, no. 7 (July 1994): 306–8.
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• O’Connor, C. M., R. Meese, R. Carney, J. Smith, E. Conn, J. Burks, C. Hartman, S. Roark, N. Shadoff, and M. Heard. “A randomized trial of intravenous heparin in conjunction with anistreplase (anisoylated plasminogen streptokinase activator complex) in acute myocardial infarction: the Duke University Clinical Cardiology Study (DUCCS) 1.” J Am Coll Cardiol 23, no. 1 (January 1994): 11–18. https://doi.org/10.1016/0735-1097(94)90496-0.
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• Van Trigt, P., J. Douglas, P. K. Smith, P. T. Campbell, T. C. Wall, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, and G. R. Corey. “A prospective trial of subxiphoid pericardiotomy in the diagnosis and treatment of large pericardial effusion. A follow-up report.” Ann Surg 218, no. 6 (December 1993): 777–82. https://doi.org/10.1097/00000658-199312000-00012.
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• Jiang, W., J. Hayano, E. R. Coleman, M. W. Hanson, D. J. Frid, C. O’Connor, D. Thurber, R. A. Waugh, and J. A. Blumenthal. “Relation of cardiovascular responses to mental stress and cardiac vagal activity in coronary artery disease.” Am J Cardiol 72, no. 7 (September 1, 1993): 551–54. https://doi.org/10.1016/0002-9149(93)90350-l.
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• Corey, G. R., P. T. Campbell, P. Van Trigt, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, J. A. Kisslo, and T. C. Wall. “Etiology of large pericardial effusions.” Am J Med 95, no. 2 (August 1993): 209–13. https://doi.org/10.1016/0002-9343(93)90262-n.
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• Kenney, R. T., J. S. Li, W. A. Clyde, T. C. Wall, C. M. O’Connor, P. T. Campbell, P. Van Trigt, and G. R. Corey. “Mycoplasmal pericarditis: evidence of invasive disease.” Clin Infect Dis 17 Suppl 1 (August 1993): S58–62. https://doi.org/10.1093/clinids/17.supplement_1.s58.
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• Krucoff, M. W., M. A. Croll, J. E. Pope, C. B. Granger, C. M. O’Connor, K. N. Sigmon, B. L. Wagner, J. A. Ryan, K. L. Lee, and D. J. Kereiakes. “Continuous 12-lead ST-segment recovery analysis in the TAMI 7 study. Performance of a noninvasive method for real-time detection of failed myocardial reperfusion.” Circulation 88, no. 2 (August 1993): 437–46. https://doi.org/10.1161/01.cir.88.2.437.
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• Slaughter, T. F., E. A. Mody, H. N. Oldham, J. G. Reves, C. M. O’Connor, J. K. Parker, and C. S. Greenberg. “Management of a patient with type IIC von Willebrand's disease during coronary artery bypass graft surgery.” Anesthesiology 78, no. 1 (January 1993): 195–97. https://doi.org/10.1097/00000542-199301000-00027.
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• Wall, T. C., P. T. Campbell, C. M. O’Connor, P. Van Trigt, R. T. Kenney, K. H. Sheikh, J. A. Kisslo, and G. R. Corey. “Diagnosis and management (by subxiphoid pericardiotomy) of large pericardial effusions causing cardiac tamponade.” Am J Cardiol 69, no. 12 (April 15, 1992): 1075–78. https://doi.org/10.1016/0002-9149(92)90866-w.
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• Campbell, P. T., P. Van Trigt, T. C. Wall, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, J. A. Kisslo, M. E. Baker, and G. R. Corey. “Subxiphoid pericardiotomy in the diagnosis and management of large pericardial effusions associated with malignancy.” Chest 101, no. 4 (April 1992): 938–43. https://doi.org/10.1378/chest.101.4.938.
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• Ortel, T. L., J. P. Gockerman, R. M. Califf, R. L. McCann, C. M. O’Connor, D. M. Metzler, and C. S. Greenberg. “Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.” Thromb Haemost 67, no. 3 (March 2, 1992): 292–96.
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• O’Connor, C. M., and R. M. Califf. “Aggressive therapy of acute MI in the elderly.” Hosp Pract (Off Ed) 27, no. 2 (February 15, 1992): 59-passim. https://doi.org/10.1080/21548331.1992.11705360.
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• Uglietta, J. P., C. M. O’Connor, O. B. Boyko, H. Aldrich, E. W. Massey, and E. R. Heinz. “CT patterns of intracranial hemorrhage complicating thrombolytic therapy for acute myocardial infarction.” Radiology 181, no. 2 (November 1991): 555–59. https://doi.org/10.1148/radiology.181.2.1924804.
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• Wallis, D. E., W. E. Boden, R. Califf, M. H. Crawford, A. H. Hakki, A. S. Iskandrian, A. Labovitz, C. O’Connor, R. Sutton, and P. J. Scanlon. “Failure of adjuvant heparin to reduce myocardial ischemia in the early treatment of patients with unstable angina.” Am Heart J 122, no. 4 Pt 1 (October 1991): 949–54. https://doi.org/10.1016/0002-8703(91)90456-r.
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• O’Connor, C. M., R. M. Califf, E. W. Massey, D. B. Mark, D. J. Kereiakes, R. J. Candela, C. Abbottsmith, B. George, R. S. Stack, and L. Aronson. “Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis.” J Am Coll Cardiol 16, no. 3 (September 1990): 533–40. https://doi.org/10.1016/0735-1097(90)90338-p.
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• Blumenthal, J. A., and C. O’Connor. “Stress and silent myocardial ischemia. A new research study at Duke University Medical Center.” N C Med J 51, no. 4 (April 1990): 135–38.
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• Mark, D. B., M. A. Hlatky, C. M. O’Connor, D. B. Pryor, T. C. Wall, M. B. Honan, H. R. Phillips, and R. M. Califf. “Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues.” J Am Coll Cardiol 12, no. 6 Suppl A (December 1988): 32A-43A. https://doi.org/10.1016/0735-1097(88)92639-3.
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• Stack, R. S., R. M. Califf, T. Hinohara, H. R. Phillips, D. B. Pryor, C. A. Simonton, E. B. Carlson, K. G. Morris, V. S. Behar, and Y. Kong. “Survival and cardiac event rates in the first year after emergency coronary angioplasty for acute myocardial infarction.” J Am Coll Cardiol 11, no. 6 (June 1988): 1141–49. https://doi.org/10.1016/0735-1097(88)90274-4.
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• Simonton, C. A., D. B. Mark, T. Hinohara, D. S. Rendall, H. R. Phillips, R. H. Peter, V. S. Behar, Y. Kong, W. G. O’Callaghan, and C. O’Connor. “Late restenosis after emergent coronary angioplasty for acute myocardial infarction: comparison with elective coronary angioplasty.” J Am Coll Cardiol 11, no. 4 (April 1988): 698–705. https://doi.org/10.1016/0735-1097(88)90198-2.
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• Hlatky, M. A., H. Cotugno, C. O’Connor, D. B. Mark, D. B. Pryor, and R. M. Califf. “Adoption of thrombolytic therapy in the management of acute myocardial infarction.” Am J Cardiol 61, no. 8 (March 1, 1988): 510–14. https://doi.org/10.1016/0002-9149(88)90755-2.
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• Hlatky, M. A., H. E. Cotugno, D. B. Mark, C. O’Connor, R. M. Califf, and D. B. Pryor. “Trends in physician management of uncomplicated acute myocardial infarction, 1970 to 1987.” Am J Cardiol 61, no. 8 (March 1, 1988): 515–18. https://doi.org/10.1016/0002-9149(88)90756-4.
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• Stack, R. S., C. M. O’Connor, D. B. Mark, T. Hinohara, H. R. Phillips, M. M. Lee, N. M. Ramirez, W. G. O’Callaghan, C. A. Simonton, and E. B. Carlson. “Coronary perfusion during acute myocardial infarction with a combined therapy of coronary angioplasty and high-dose intravenous streptokinase.” Circulation 77, no. 1 (January 1988): 151–61. https://doi.org/10.1161/01.cir.77.1.151.
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• Boswick, J. M., K. L. Lee, L. G. Aronson, C. M. O’Connor, M. B. Honan, R. M. Califf, and D. B. Pryor. “USE OF COMPUTERIZED STATISTICAL MODELS TO EDUCATE MEDICAL HOUSESTAFF IN ESTIMATING CLINICAL OUTCOMES.” Proceedings  Annual Symposium on Computer Applications in Medical Care, December 1, 1987, 162–65.
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