Christopher Michael O'Connor

Christopher Michael O'Connor
Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology

Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.

Current Appointments & Affiliations

Richard Sean Stack, M.D. / Guidant Foundation Professor of Cardiology, Medicine, Clinical Pharmacology, Medicine 2014
Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2016

Contact Information

7401 Hosp North, Durham, NC 27710
Duke Box 3356, Durham, NC 27710
oconn002@mc.duke.edu (919) 681-6195

Background
Education, Training, & Certifications
- Fellow in Cardiology, Medicine, Duke University 1988 - 1989
- Chief Medical Resident - VAMC, Medicine, Duke University 1987 - 1988
- Cardiology Fellow, Medicine, Duke University 1986 - 1987
- Medical Resident, Medicine, Duke University 1983 - 1986
- M.D., University of Maryland, College Park 1983
Duke Appointment History
- Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 1985 - 2016
- Associate Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2001 - 2016
- Director, of the Heart Center/Cardiovascular CSU, Medicine, Clinical Science Departments 2007 - 2016
- Adjunct Professor in the Department of Medicine, Medicine, Cardiology, Medicine 2015 - 2016
- Professor of Medicine, Medicine, Cardiology, Medicine 2003 - 2015
- Chief, Division of Clinical Pharmacology in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2001 - 2015
- Chief, Division of Cardiology, Medicine, Cardiology, Medicine 2012 - 2015
- Acting Chief of the Division of Cardiology, Medicine, Cardiology, Medicine 2010 - 2012
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 1999 - 2003
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 1996 - 1999
- Assistant Professor of Medicine, Medicine, Cardiology, Medicine 1990 - 1996
- Associate in the Department of Medicine, Medicine, Clinical Science Departments 1989 - 1990
Recognition
In the News
- NOV 27, 2018
  
  Duke Faculty Plentiful On ‘Highly Cited’ List
Expertise
Subject Headings
Research
Selected Grants
- Duke-UNC Clinical Hematology and Transfusion Research Career Development Program awarded by National Institutes of Health 2006 - 2019
- STICHES awarded by National Institutes of Health 2011 - 2019
- GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC) awarded by National Institutes of Health 2012 - 2017
- Palliative Care in Heart Failure (PAL-HF) awarded by National Institutes of Health 2011 - 2016
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2011 - 2016
- Coping Skills Training in Heart Failure: Outcomes and Mechanisms awarded by National Institutes of Health 2009 - 2015
- Responses of Myocardial Ischemia to Sertraline Treatment awarded by National Institutes of Health 2006 - 2013
- Heart Failure Clinical Research Network awarded by National Institutes of Health 2006 - 2011
- STICH Trial - Coordinating Center awarded by National Institutes of Health 2002 - 2011
- Pharmacometabolomics Research Network awarded by National Institutes of Health 2010 - 2011
- Safety and Efficacy of Sertraline for Depression CHF awarded by National Institutes of Health 2003 - 2011
- A CHF Trial Investigating Outcomes of Exercise Training awarded by National Institutes of Health 2002 - 2010
- HF Action Supplement awarded by National Institutes of Health 2002 - 2010
- Inflammation & Prognosis in Decompensated Heart Failure awarded by National Institutes of Health 2004 - 2010
- ESCAPE - Evaluation Study of Congestive Heart Failure and Pulmonary Artery.. awarded by National Institutes of Health 1999 - 2008
- ESCAPE Mechanistic Substudy Grant Application awarded by National Institutes of Health 2001 - 2006
- Enhancing Recovery In Coronary Heart Disease Patients awarded by National Institutes of Health 1995 - 2005
- Stress & Congestive Heart Failure:Prognosis & Mechanisms awarded by National Institutes of Health 1999 - 2005
- Warfarin and antiplatelet therapy study in chronic heart failure (CSP#442) awarded by Department of Veterans Affairs 1999 - 2004
- Inflammatory Biomarkers in Depressed CHF Patients awarded by National Institutes of Health 2003 - 2004
- Depression In Elderly Cardiac Patients awarded by National Institutes of Health 1994 - 2003
- Beta-Blocker Evaluation Of Survival Trial (Best) awarded by Department of Veterans Affairs 1995 - 2001
- Heart Failure Specialized Center Of Research awarded by National Institutes of Health 1995 - 1999
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Psotka, MA, Ammon, SE, Fiuzat, M, Bozkurt, B, Chung, ES, Cole, RT, Greene, SJ, Kraus, D, Ky, B, McIlvennan, CK, Shah, P, Teerlink, JR, Walsh, MN, Jessup, M, and O'Connor, CM. "Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey." Jacc. Heart Failure 7, no. 5 (May 2019): 431-438. Full Text
  - Russell, FM, Ehrman, RR, Ferre, R, Gargani, L, Noble, V, Rupp, J, Collins, SP, Hunter, B, Lane, KA, Levy, P, Li, X, O'Connor, C, and Pang, PS. "Design and rationale of the B-lines lung ultrasound guided emergency department management of acute heart failure (BLUSHED-AHF) pilot trial." Heart and Lung 48, no. 3 (May 1, 2019): 186-192. Full Text
  - O'Connor, CM. "Heart Failure Fake News: How Do We Distinguish the Truth?." Jacc. Heart Failure 7, no. 4 (April 2019): 363-null. Full Text
  - Taylor, RS, Walker, S, Smart, NA, Piepoli, MF, Warren, FC, Ciani, O, Whellan, D, O'Connor, C, Keteyian, SJ, Coats, A, Davos, CH, Dalal, HM, Dracup, K, Evangelista, LS, Jolly, K, Myers, J, Nilsson, BB, Passino, C, Witham, MD, Yeh, GY, and ExTraMATCH II Collaboration, . "Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis." Journal of the American College of Cardiology 73, no. 12 (April 2019): 1430-1443. Full Text
  - Daubert, MA, Adams, K, Yow, E, Barnhart, HX, Douglas, PS, Rimmer, S, Norris, C, Cooper, L, Leifer, E, Desvigne-Nickens, P, Anstrom, K, Fiuzat, M, Ezekowitz, J, Mark, DB, O'Connor, CM, Januzzi, J, and Felker, GM. "NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF." Jacc. Heart Failure 7, no. 2 (February 2019): 158-168. Full Text
  - Luo, N, O'Connor, CM, Cooper, LB, Sun, J-L, Coles, A, Reed, SD, Whellan, DJ, Piña, IL, Kraus, WE, and Mentz, RJ. "Relationship between changing patient-reported outcomes and subsequent clinical events in patients with chronic heart failure: insights from HF-ACTION." European Journal of Heart Failure 21, no. 1 (January 2019): 63-70. Full Text
  - O'Connor, CM. "Aviation Emergencies for Heart Failure Cardiologists: A New Twist to the Heart Team." Jacc. Heart Failure 6, no. 12 (December 2018): 1047-1048. Full Text
  - Taylor, RS, Walker, S, Smart, NA, Piepoli, MF, Warren, FC, Ciani, O, O'Connor, C, Whellan, D, Keteyian, SJ, Coats, A, Davos, CH, Dalal, HM, Dracup, K, Evangelista, L, Jolly, K, Myers, J, McKelvie, RS, Nilsson, BB, Passino, C, Witham, MD, Yeh, GY, Zwisler, A-DO, and ExTraMATCH II Collaboration, . "Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials." European Journal of Heart Failure 20, no. 12 (December 2018): 1735-1743. (Review) Full Text
  - Fudim, M, Parikh, KS, Dunning, A, DeVore, AD, Mentz, RJ, Schulte, PJ, Armstrong, PW, Ezekowitz, JA, Tang, WHW, McMurray, JJV, Voors, AA, Drazner, MH, O'Connor, CM, Hernandez, AF, and Patel, CB. "Relation of Volume Overload to Clinical Outcomes in Acute Heart Failure (From ASCEND-HF)." The American Journal of Cardiology 122, no. 9 (November 2018): 1506-1512. Full Text
  - Hamo, CE, O'Connor, C, Metra, M, Udelson, JE, Gheorghiade, M, and Butler, J. "A Critical Appraisal of Short-Term End Points in Acute Heart Failure Clinical Trials." Journal of Cardiac Failure 24, no. 11 (November 2018): 783-792. (Review) Full Text
  - Mark, DB, Cowper, PA, Anstrom, KJ, Sheng, S, Daniels, MR, Knight, JD, Baloch, KN, Davidson-Ray, L, Fiuzat, M, Januzzi, JL, Whellan, DJ, Piña, IL, Ezekowitz, JA, Adams, KF, Cooper, LS, O'Connor, CM, and Felker, GM. "Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure." Journal of the American College of Cardiology 72, no. 21 (November 2018): 2551-2562. Full Text
  - O'Connor, CM. "COAPTing Heart Failure Physicians, Interventional Cardiologists, and CardioThoracic Surgeons: A New Opportunity for Patients." Jacc. Heart Failure 6, no. 11 (November 2018): 967-968. Full Text
  - Fudim, M, Loungani, R, Doerfler, SM, Coles, A, Greene, SJ, Cooper, LB, Fiuzat, M, O'Connor, CM, Rogers, JG, and Mentz, RJ. "Worsening renal function during decongestion among patients hospitalized for heart failure: Findings from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial." American Heart Journal 204 (October 2018): 163-173. Full Text
  - Greene, SJ, Hernandez, AF, Sun, J-L, Butler, J, Armstrong, PW, Ezekowitz, JA, Zannad, F, Ferreira, JP, Coles, A, Metra, M, Voors, AA, Califf, RM, O'Connor, CM, and Mentz, RJ. "Relationship Between Enrolling Country Income Level and Patient Profile, Protocol Completion, and Trial End Points." Circulation. Cardiovascular Quality and Outcomes 11, no. 10 (October 2018): e004783-null. Full Text
  - Jiang, W, Whellan, DJ, Adams, KF, Babyak, MA, Boyle, SH, Wilson, JL, Patel, CB, Rogers, JG, Harris, WS, and O'Connor, CM. "Long-Chain Omega-3 Fatty Acid Supplements in Depressed Heart Failure Patients: Results of the OCEAN Trial." Jacc. Heart Failure 6, no. 10 (October 2018): 833-843. Full Text
  - O'Connor, CM. "Depression in Heart Failure: Beyond a SADHART." Jacc: Heart Failure 6, no. 10 (October 1, 2018): 885-886. Full Text
  - Sharma, A, Cooper, LB, Fiuzat, M, Mentz, RJ, Ferreira, JP, Butler, J, Fitchett, D, Moses, AC, O'Connor, C, and Zannad, F. "Antihyperglycemic Therapies to Treat Patients With Heart Failure and Diabetes Mellitus." Jacc. Heart Failure 6, no. 10 (October 2018): 813-822. (Review) Full Text
  - Tahhan, AS, Vaduganathan, M, Greene, SJ, Fonarow, GC, Fiuzat, M, Jessup, M, Lindenfeld, J, O'Connor, CM, and Butler, J. "Enrollment of Older Patients, Women, and Racial and Ethnic Minorities in Contemporary Heart Failure Clinical Trials: A Systematic Review." Jama Cardiology 3, no. 10 (October 2018): 1011-1019. Full Text
  - Ambrosy, AP, Mulder, H, Coles, A, Krauss, WE, Lam, CSP, McCullough, PA, Pina, I, Tromp, J, Whellan, DJ, O'Connor, CM, and Mentz, RJ. "Renal Function and Exercise Training in AmbulatoryHeart Failure Patients With a Reduced Ejection Fraction." The American Journal of Cardiology 122, no. 6 (September 2018): 999-1007. Full Text
  - Cooper, LB, Yap, J, Tay, WT, Teng, T-HK, MacDonald, M, Anand, IS, Sharma, A, O'Connor, CM, Kraus, WE, Mentz, RJ, Lam, CS, and HF-ACTION and ASIAN-HF Investigators, . "Multi-ethnic comparisons of diabetes in heart failure with reduced ejection fraction: insights from the HF-ACTION trial and the ASIAN-HF registry." European Journal of Heart Failure 20, no. 9 (September 2018): 1281-1289. Full Text
  - Greene, SJ, Mentz, RJ, Fiuzat, M, Butler, J, Solomon, SD, Ambrosy, AP, Mehta, C, Teerlink, JR, Zannad, F, and O'Connor, CM. "Reassessing the Role of Surrogate End Points in Drug Development for Heart Failure." Circulation 138, no. 10 (September 2018): 1039-1053. Full Text
  - O'Connor, CM. "Politically Correct Heart Failure Research in America to Avoid Geographic Variation." Jacc: Heart Failure 6, no. 9 (September 1, 2018): 805-806. Full Text
  - Grodin, JL, Butler, J, Metra, M, Felker, GM, Voors, AA, McMurray, JJ, Armstrong, PW, Hernandez, AF, O'Connor, C, Starling, RC, and Tang, WHW. "Circulating Cardiac Troponin I Levels Measured by a Novel Highly Sensitive Assay in Acute Decompensated Heart Failure: Insights From the ASCEND-HF Trial." Journal of Cardiac Failure 24, no. 8 (August 2018): 512-519. Full Text
  - O'Connor, CM. "HFpEF: From Early Observations to Worldwide Awareness." Jacc: Heart Failure 6, no. 8 (August 1, 2018): 718-719. Full Text
  - Parikh, KS, Fiuzat, M, Davis, G, Neely, M, Blain-Nelson, P, Whellan, DJ, Abraham, WT, Adams, KF, Felker, GM, Liggett, SB, O'Connor, CM, and Bristow, MR. "Dose Response of β-Blockers in Adrenergic Receptor Polymorphism Genotypes." Circulation. Genomic and Precision Medicine 11, no. 8 (August 2018): e002210-null. Full Text
  - Parikh, KS, Sharma, K, Fiuzat, M, Surks, HK, George, JT, Honarpour, N, Depre, C, Desvigne-Nickens, P, Nkulikiyinka, R, Lewis, GD, Gomberg-Maitland, M, O'Connor, CM, Stockbridge, N, Califf, RM, Konstam, MA, Januzzi, JL, Solomon, SD, Borlaug, BA, Shah, SJ, Redfield, MM, and Felker, GM. "Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials." Jacc. Heart Failure 6, no. 8 (August 2018): 619-632. (Review) Full Text Open Access Copy
  - Fudim, M, O'Connor, CM, Mulder, H, Coles, A, Bhatt, AS, Ambrosy, AP, Kraus, WE, Piña, IL, Whellan, DJ, and Mentz, RJ. "Loop diuretic adjustments in patients with chronic heart failure: Insights from HF-ACTION." American Heart Journal (July 29, 2018). Full Text
  - Daubert, MA, Whellan, DJ, Woehrle, H, Tasissa, G, Anstrom, KJ, Lindenfeld, J, Benjafield, A, Blase, A, Punjabi, N, Fiuzat, M, Oldenburg, O, and O'Connor, CM. "Treatment of sleep-disordered breathing in heart failure impacts cardiac remodeling: Insights from the CAT-HF Trial." American Heart Journal 201 (July 2018): 40-48. Full Text
  - O'Connor, CM. "Cardiovascular Drug Pricing: Less Innovation for More Access?." Jacc: Heart Failure 6, no. 7 (July 1, 2018): 613-614. Full Text
  - Vaduganathan, M, Patel, RB, Mentz, RJ, Subacius, H, Chatterjee, NA, Greene, SJ, Ambrosy, AP, Maggioni, AP, Udelson, JE, Swedberg, K, Konstam, MA, O'Connor, CM, Butler, J, Gheorghiade, M, and Zannad, F. "Sudden Death After Hospitalization for Heart Failure With Reduced Ejection Fraction (from the EVEREST Trial)." The American Journal of Cardiology 122, no. 2 (July 2018): 255-260. Full Text
  - Warraich, HJ, O'Connor, C, Wu, A, Coles, A, Kraus, WE, Piña, IL, Whellan, DJ, and Mentz, RJ. "Differences Between Patients Enrolled Early and Late During Clinical Trial Recruitment: Insights From the HF-ACTION Trial." Circulation. Cardiovascular Quality and Outcomes 11, no. 7 (July 2018): e004643-null. (Letter) Full Text
  - Ambrosy, AP, Mentz, RJ, Fiuzat, M, Cleland, JGF, Greene, SJ, O'Connor, CM, Teerlink, JR, Zannad, F, and Solomon, SD. "The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions." European Journal of Heart Failure 20, no. 6 (June 2018): 963-972. (Review) Full Text
  - O’Connor, CM. "Dying With Dignity and Heart Failure." Jacc: Heart Failure 6, no. 6 (June 2018): 536-537. Full Text
  - Ahmad, T, Jackson, K, Rao, VS, Tang, WHW, Brisco-Bacik, MA, Chen, HH, Felker, GM, Hernandez, AF, O'Connor, CM, Sabbisetti, VS, Bonventre, JV, Wilson, FP, Coca, SG, and Testani, JM. "Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury." Circulation 137, no. 19 (May 2018): 2016-2028. Full Text
  - Ambrosy, AP, Bhatt, AS, Stebbins, AL, Wruck, LM, Fudim, M, Greene, SJ, Kraus, WE, O'Connor, CM, Piña, IL, Whellan, DJ, and Mentz, RJ. "Prevalent digoxin use and subsequent risk of death or hospitalization in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) randomized controlled trial." American Heart Journal 199 (May 2018): 97-104. Full Text
  - O'Connor, CM. "What's One More Day?." Jacc: Heart Failure 6, no. 5 (May 1, 2018): 438-null. Full Text
  - Rubio-Gracia, J, Demissei, BG, Ter Maaten, JM, Cleland, JG, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, BA, Givertz, MM, Bloomfield, DM, Dittrich, H, Damman, K, Pérez-Calvo, JI, and Voors, AA. "Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure." International Journal of Cardiology 258 (May 2018): 185-191. Full Text
  - Ahmad, T, Lund, LH, Rao, P, Ghosh, R, Warier, P, Vaccaro, B, Dahlström, U, O'Connor, CM, Felker, GM, and Desai, NR. "Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients." Journal of the American Heart Association 7, no. 8 (April 12, 2018). Full Text
  - Cerbin, LP, Ambrosy, AP, Greene, SJ, Armstrong, PW, Butler, J, Coles, A, DeVore, AD, Ezekowitz, JA, Hernandez, AF, Metra, M, Starling, RC, Tang, W, Teerlink, JR, Voors, AA, Wu, A, O'Connor, CM, and Mentz, RJ. "Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial." Jacc. Heart Failure 6, no. 4 (April 2018): 298-307. Full Text
  - O'Connor, CM, and Bristow, MR. "Changing the Research Culture in the United States." Jacc: Heart Failure 6, no. 4 (April 1, 2018): 344-345. Full Text
  - Hicks, KA, Mahaffey, KW, Mehran, R, Nissen, SE, Wiviott, SD, Dunn, B, Solomon, SD, Marler, JR, Teerlink, JR, Farb, A, Morrow, DA, Targum, SL, Sila, CA, Thanh Hai, MT, Jaff, MR, Joffe, HV, Cutlip, DE, Desai, AS, Lewis, EF, Gibson, CM, Landray, MJ, Lincoff, AM, White, CJ, Brooks, SS, Rosenfield, K, Domanski, MJ, Lansky, AJ, McMurray, JJV, Tcheng, JE, Steinhubl, SR, Burton, P, Mauri, L, O'Connor, CM, Pfeffer, MA, Hung, HMJ, Stockbridge, NL, Chaitman, BR, Temple, RJ, and Standardized Data Collection for Cardiovascular Trials Initiative (SCTI), . "2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials." Journal of the American College of Cardiology 71, no. 9 (March 2018): 1021-1034. (Review) Full Text
  - O'Connor, CM. "Heart Failure Health Care 2018: Challenges and Opportunities." Jacc: Heart Failure 6, no. 3 (March 1, 2018): 262-263. Full Text
  - Bhatt, AS, Cooper, LB, Ambrosy, AP, Clare, RM, Coles, A, Joyce, E, Krishnamoorthy, A, Butler, J, Felker, GM, Ezekowitz, JA, Armstrong, PW, Hernandez, AF, O'Connor, CM, and Mentz, RJ. "Interaction of Body Mass Index on the Association Between N-Terminal-Pro-b-Type Natriuretic Peptide and Morbidity and Mortality in Patients With Acute Heart Failure: Findings From ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure)." Journal of the American Heart Association 7, no. 3 (February 3, 2018). Full Text
  - Armstrong, PW, Roessig, L, Patel, MJ, Anstrom, KJ, Butler, J, Voors, AA, Lam, CSP, Ponikowski, P, Temple, T, Pieske, B, Ezekowitz, J, Hernandez, AF, Koglin, J, and O'Connor, CM. "A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Efficacy and Safety of the Oral Soluble Guanylate Cyclase Stimulator: The VICTORIA Trial." Jacc. Heart Failure 6, no. 2 (February 2018): 96-104. (Review) Full Text
  - Cotter, G, Metra, M, Davison, BA, Jondeau, G, Cleland, JGF, Bourge, RC, Milo, O, O'Connor, CM, Parker, JD, Torre-Amione, G, van Veldhuisen, DJ, Kobrin, I, Rainisio, M, Senger, S, Edwards, C, McMurray, JJV, Teerlink, JR, and VERITAS Investigators, . "Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe?." European Journal of Heart Failure 20, no. 2 (February 2018): 317-322. Full Text
  - Fudim, M, O'Connor, CM, Dunning, A, Ambrosy, AP, Armstrong, PW, Coles, A, Ezekowitz, JA, Greene, SJ, Metra, M, Starling, RC, Voors, AA, Hernandez, AF, Michael Felker, G, and Mentz, RJ. "Aetiology, timing and clinical predictors of early vs. late readmission following index hospitalization for acute heart failure: insights from ASCEND-HF." European Journal of Heart Failure 20, no. 2 (February 2018): 304-314. Full Text
  - Hicks, KA, Mahaffey, KW, Mehran, R, Nissen, SE, Wiviott, SD, Dunn, B, Solomon, SD, Marler, JR, Teerlink, JR, Farb, A, Morrow, DA, Targum, SL, Sila, CA, Hai, MTT, Jaff, MR, Joffe, HV, Cutlip, DE, Desai, AS, Lewis, EF, Gibson, CM, Landray, MJ, Lincoff, AM, White, CJ, Brooks, SS, Rosenfield, K, Domanski, MJ, Lansky, AJ, McMurray, JJV, Tcheng, JE, Steinhubl, SR, Burton, P, Mauri, L, O'Connor, CM, Pfeffer, MA, Hung, HMJ, Stockbridge, NL, Chaitman, BR, Temple, RJ, and Standardized Data Collection for Cardiovascular Trials Initiative (SCTI), . "2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials." Circulation 137, no. 9 (February 2018): 961-972. (Review) Full Text
  - O'Connor, CM. "Smartphone, Mom, and HFpEF." Jacc: Heart Failure 6, no. 2 (February 1, 2018): 176-null. Full Text
  - O'Connor, CM, Psotka, MA, Fiuzat, M, Lindenfeld, J, Abraham, WT, Bristow, MR, Canos, D, Harrington, RA, Hillebrenner, M, Jessup, M, Malik, FI, Solomon, SD, Stockbridge, N, Tcheng, JE, Unger, EF, Whellan, DJ, Zuckerman, B, and Califf, RM. "Improving Heart Failure Therapeutics Development in the United States: The Heart Failure Collaboratory." Journal of the American College of Cardiology 71, no. 4 (January 2018): 443-453. (Review) Full Text
  - O’Connor, CM. "I Don’t Care How Low My BNP Is, I Want to Feel Good." Jacc: Heart Failure 6, no. 1 (January 2018): 82-83. Full Text
  - Pastva, AM, Duncan, PW, Reeves, GR, Nelson, MB, Whellan, DJ, O'Connor, CM, Eggebeen, JD, Hewston, LA, Taylor, KM, Mentz, RJ, Rosenberg, PB, and Kitzman, DW. "Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial." Contemporary Clinical Trials 64 (January 2018): 118-127. Full Text
  - Daubert, MA, Yow, E, Dunn, G, Marchev, S, Barnhart, H, Douglas, PS, O'Connor, C, Goldstein, S, Udelson, JE, and Sabbah, HN. "Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide." Circulation. Heart Failure 10, no. 12 (December 2017). Full Text
  - Alenezi, F, Brummett, BH, Boyle, SH, Samad, Z, Babyak, MA, Alzaeim, N, Wilson, J, Romano, MMD, Sun, JL, Ersboll, M, O'Connor, CM, Velazquez, EJ, and Jiang, W. "Usefulness of Myocardial Annular Velocity Change During Mental Stress to Predict Cardiovascular Outcome in Patients With Coronary Artery Disease (From the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment Trial)." The American Journal of Cardiology 120, no. 9 (November 2017): 1495-1500. Full Text
  - O'Connor, CM. "Goodbye Mihai: We Will Miss You." Jacc. Heart Failure 5, no. 11 (November 2017): 848-849. Full Text
  - O'Connor, CM. "Q&A With the JACC: Heart Failure Editor-in-Chief: Marking the 5-Year Milestone." Jacc. Heart Failure 5, no. 10 (October 2017): 758-759. Full Text
  - Sharma, A, Demissei, BG, Tromp, J, Hillege, HL, Cleland, JG, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Davison, BA, Givertz, MM, Bloomfield, DM, Dittrich, H, van Veldhuisen, DJ, Cotter, G, Ezekowitz, JA, Khan, MAF, and Voors, AA. "A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure." European Journal of Heart Failure 19, no. 10 (October 2017): 1310-1320. Full Text
  - Sharma, A, Stevens, SR, Lucas, J, Fiuzat, M, Adams, KF, Whellan, DJ, Donahue, MP, Kitzman, DW, Piña, IL, Zannad, F, Kraus, WE, O'Connor, CM, and Felker, GM. "Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study." Jacc. Heart Failure 5, no. 10 (October 2017): 724-734. Full Text
  - Luo, N, Teng, T-HK, Tay, WT, Anand, IS, Kraus, WE, Liew, HB, Ling, LH, O'Connor, CM, Piña, IL, Richards, AM, Shimizu, W, Whellan, DJ, Yap, J, Lam, CSP, Mentz, RJ, ASIAN-HF, , and HF-ACTION investigators, . "Multinational and multiethnic variations in health-related quality of life in patients with chronic heart failure." American Heart Journal 191 (September 2017): 75-81. Full Text
  - O'Connor, CM. "America and Apple Pie: How Do We Change the American Health Care System?." Jacc. Heart Failure 5, no. 9 (September 2017): 686-687. Full Text
  - Sherwood, A, Hill, LK, Blumenthal, JA, Adams, KF, Paine, NJ, Koch, GG, O'Connor, CM, Johnson, KS, and Hinderliter, AL. "Blood pressure reactivity to psychological stress is associated with clinical outcomes in patients with heart failure." American heart journal 191 (September 2017): 82-90. Full Text
  - O'Connor, CM. "Does Institutional Memory Matter?." Jacc. Heart Failure 5, no. 8 (August 2017): 616-null. Full Text
  - O'Connor, CM. "A Decade With Editorial Mentors: The Day They Dropped the Mic." Jacc. Heart Failure 5, no. 7 (July 2017): 541-542. Full Text
  - Rogers, JG, Patel, CB, Mentz, RJ, Granger, BB, Steinhauser, KE, Fiuzat, M, Adams, PA, Speck, A, Johnson, KS, Krishnamoorthy, A, Yang, H, Anstrom, KJ, Dodson, GC, Taylor, DH, Kirchner, JL, Mark, DB, O'Connor, CM, and Tulsky, JA. "Palliative Care in Heart Failure: The PAL-HF Randomized, Controlled Clinical Trial." Journal of the American College of Cardiology 70, no. 3 (July 2017): 331-341. Full Text
  - Tromp, J, Khan, MAF, Mentz, RJ, O'Connor, CM, Metra, M, Dittrich, HC, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JGF, Givertz, MM, Bloomfield, DM, Van Veldhuisen, DJ, Hillege, HL, Voors, AA, and van der Meer, P. "Biomarker Profiles of Acute Heart Failure Patients With a Mid-Range Ejection Fraction." Jacc. Heart Failure 5, no. 7 (July 2017): 507-517. Full Text
  - Banks, A, Broderick, S, Chiswell, K, Shaw, L, Devore, A, Fiuzat, M, O'Connor, C, Felker, GM, Velazquez, E, and Mentz, R. "Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease)." The American Journal of Cardiology 119, no. 11 (June 2017): 1703-1709. Full Text
  - Cleland, JGF, Teerlink, JR, Davison, BA, Shoaib, A, Metra, M, Senger, S, Milo, O, Cotter, G, Bourge, RC, Parker, JD, Jondeau, G, Krum, H, O'Connor, CM, Torre-Amione, G, van Veldhuisen, DJ, McMurray, JJV, and VERITAS Investigators, . "Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS)." European Journal of Heart Failure 19, no. 6 (June 2017): 739-747. Full Text
  - Demissei, BG, Postmus, D, Cleland, JG, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, BA, Givertz, MM, Bloomfield, DM, van Veldhuisen, DJ, Dittrich, HC, Hillege, HL, and Voors, AA. "Plasma biomarkers to predict or rule out early post-discharge events after hospitalization for acute heart failure." European Journal of Heart Failure 19, no. 6 (June 2017): 728-738. Full Text
  - Greene, SJ, Hernandez, AF, Dunning, A, Ambrosy, AP, Armstrong, PW, Butler, J, Cerbin, LP, Coles, A, Ezekowitz, JA, Metra, M, Starling, RC, Teerlink, JR, Voors, AA, O'Connor, CM, and Mentz, RJ. "Hospitalization for Recently Diagnosed Versus Worsening Chronic Heart Failure: From the ASCEND-HF Trial." Journal of the American College of Cardiology 69, no. 25 (June 2017): 3029-3039. Full Text
  - O'Connor, CM. "Development of Acute Decompensated Heart Failure Therapies: Is the Journey Over?." Jacc. Heart Failure 5, no. 6 (June 2017): 464-465. Full Text
  - Raslan, IR, Brown, P, Westerhout, CM, Ezekowitz, JA, Hernandez, AF, Starling, RC, O'Connor, C, McAlister, FA, Rowe, BH, Armstrong, PW, and van Diepen, S. "Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score." American Heart Journal 188 (June 2017): 127-135. Full Text
  - O'Connor, CM. "High Heart Failure Readmission Rates: Is It the Health System's Fault?." Jacc. Heart Failure 5, no. 5 (May 2017): 393-null. Full Text
  - Packer, M, Holcomb, R, Abraham, WT, Anker, S, Dickstein, K, Filippatos, G, Krum, H, Maggioni, AP, McMurray, JJV, Mebazaa, A, O'Connor, C, Peacock, F, Ponikowski, P, Ruschitzka, F, van Veldhuisen, DJ, Holzmeister, J, and TRUE-AHF Investigators and Committees, . "Rationale for and design of the TRUE-AHF trial: the effects of ularitide on the short-term clinical course and long-term mortality of patients with acute heart failure." European Journal of Heart Failure 19, no. 5 (May 2017): 673-681. Full Text
  - Packer, M, O'Connor, C, McMurray, JJV, Wittes, J, Abraham, WT, Anker, SD, Dickstein, K, Filippatos, G, Holcomb, R, Krum, H, Maggioni, AP, Mebazaa, A, Peacock, WF, Petrie, MC, Ponikowski, P, Ruschitzka, F, van Veldhuisen, DJ, Kowarski, LS, Schactman, M, Holzmeister, J, and TRUE-AHF Investigators, . "Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure." The New England Journal of Medicine 376, no. 20 (May 2017): 1956-1964. Full Text
  - Reeves, GR, Whellan, DJ, O'Connor, CM, Duncan, P, Eggebeen, JD, Morgan, TM, Hewston, LA, Pastva, A, Patel, MJ, and Kitzman, DW. "A Novel Rehabilitation Intervention for Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Pilot Study." Jacc. Heart Failure 5, no. 5 (May 2017): 359-366. Full Text
  - Ambrosy, AP, Cerbin, LP, DeVore, AD, Greene, SJ, Kraus, WE, O'Connor, CM, Piña, IL, Whellan, DJ, Wojdyla, D, Wu, A, and Mentz, RJ. "Aerobic exercise training and general health status in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)trial." American Heart Journal 186 (April 2017): 130-138. Full Text
  - Butler, J, Hamo, CE, Udelson, JE, O'Connor, C, Sabbah, HN, Metra, M, Shah, SJ, Kitzman, DW, Teerlink, JR, Bernstein, HS, Brooks, G, Depre, C, DeSouza, MM, Dinh, W, Donovan, M, Frische-Danielson, R, Frost, RJ, Garza, D, Gohring, U-M, Hellawell, J, Hsia, J, Ishihara, S, Kay-Mugford, P, Koglin, J, Kozinn, M, Larson, CJ, Mayo, M, Gan, L-M, Mugnier, P, Mushonga, S, Roessig, L, Russo, C, Salsali, A, Satler, C, Shi, V, Ticho, B, van der Laan, M, Yancy, C, Stockbridge, N, and Gheorghiade, M. "Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations." Circulation. Heart Failure 10, no. 4 (April 2017). Full Text
  - Luo, N, Merrill, P, Parikh, KS, Whellan, DJ, Piña, IL, Fiuzat, M, Kraus, WE, Kitzman, DW, Keteyian, SJ, O'Connor, CM, and Mentz, RJ. "Exercise Training in Patients With Chronic Heart Failure and Atrial Fibrillation." Journal of the American College of Cardiology 69, no. 13 (April 2017): 1683-1691. Full Text
  - O'Connor, CM, and van Veldhuisen, DJ. "Data Sharing From the Editors' Perspective: Our Hope With Limitations." Jacc. Heart Failure 5, no. 4 (April 2017): 314-315. Full Text
  - Sun, JL, Boyle, SH, Samad, Z, Babyak, MA, Wilson, JL, Kuhn, C, Becker, RC, Ortel, TL, Williams, RB, Rogers, JG, O'Connor, CM, Velazquez, EJ, and Jiang, W. "Mental stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients." European Journal of Preventive Cardiology 24, no. 6 (April 2017): 591-599. Full Text
  - Felker, GM, Mentz, RJ, Cole, RT, Adams, KF, Egnaczyk, GF, Fiuzat, M, Patel, CB, Echols, M, Khouri, MG, Tauras, JM, Gupta, D, Monds, P, Roberts, R, and O'Connor, CM. "Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure." Journal of the American College of Cardiology 69, no. 11 (March 2017): 1399-1406. Full Text
  - Levy, WC, Li, Y, Reed, SD, Zile, MR, Shadman, R, Dardas, T, Whellan, DJ, Schulman, KA, Ellis, SJ, Neilson, M, O'Connor, CM, and HFACTION Investigators, . "Does the Implantable Cardioverter-Defibrillator Benefit Vary With the Estimated Proportional Risk of Sudden Death in Heart Failure Patients?." Jacc. Clinical Electrophysiology 3, no. 3 (March 2017): 291-298. Full Text
  - Matsue, Y, Ter Maaten, JM, Struck, J, Metra, M, O'Connor, CM, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JG, Givertz, MM, Bloomfield, DM, Dittrich, HC, van Veldhuisen, DJ, van der Meer, P, Damman, K, and Voors, AA. "Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure." Journal of Cardiac Failure 23, no. 3 (March 2017): 231-239. Full Text
  - Matsue, Y, van der Meer, P, Damman, K, Metra, M, O'Connor, CM, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JG, Givertz, MM, Bloomfield, DM, Dittrich, HC, Gansevoort, RT, Bakker, SJL, van der Harst, P, Hillege, HL, van Veldhuisen, DJ, and Voors, AA. "Blood urea nitrogen-to-creatinine ratio in the general population and in patients with acute heart failure." Heart (British Cardiac Society) 103, no. 6 (March 2017): 407-413. Full Text
  - O'Connor, CM, Whellan, DJ, Fiuzat, M, Punjabi, NM, Tasissa, G, Anstrom, KJ, Benjafield, AV, Woehrle, H, Blase, AB, Lindenfeld, J, and Oldenberg, O. "Cardiovascular Outcomes With Minute Ventilation-Targeted Adaptive Servo-Ventilation Therapy in Heart Failure: The CAT-HF Trial." Journal of the American College of Cardiology 69, no. 12 (March 2017): 1577-1587. Full Text
  - O'Connor, CM. "Is Salt Bad for You?." Jacc. Heart Failure 5, no. 3 (March 2017): 238-239. Full Text
  - Reeves, GR, Whellan, DJ, Duncan, P, O'Connor, CM, Pastva, AM, Eggebeen, JD, Hewston, LA, Morgan, TM, Reed, SD, Rejeski, WJ, Mentz, RJ, Rosenberg, PB, Kitzman, DW, and REHAB-HF Trial Investigators, . "Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale." American heart journal 185 (March 2017): 130-139. Full Text
  - Feigal, JP, Boyle, SH, Samad, Z, Velazquez, EJ, Wilson, JL, Becker, RC, Williams, RB, Kuhn, CM, Ortel, TL, Rogers, JG, O'Connor, CM, and Jiang, W. "Associations between positive emotional well-being and stress-induced myocardial ischemia: Well-being scores predict exercise-induced ischemia." Journal of psychosomatic research 93 (February 2017): 14-18. Full Text
  - Kitai, T, Grodin, JL, Mentz, RJ, Hernandez, AF, Butler, J, Metra, M, McMurray, JJ, Armstrong, PW, Starling, RC, O'Connor, CM, Swedberg, K, and Tang, WHW. "Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial." European journal of heart failure 19, no. 2 (February 2017): 241-249. Full Text
  - O'Connor, CM. "21st Century Cures: A Step Forward for Patients With Heart Failure." Jacc. Heart Failure 5, no. 2 (February 2017): 154-null. Full Text
  - Navarese, EP, Gurbel, PA, Andreotti, F, Kołodziejczak, MM, Palmer, SC, Dias, S, Buffon, A, Kubica, J, Kowalewski, M, Jadczyk, T, Laskiewicz, M, Jędrzejek, M, Brockmeyer, M, Airoldi, F, Ruospo, M, De Servi, S, Wojakowski, W, O' Connor, C, and Strippoli, GFM. "Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis." Plos One 12, no. 2 (January 2017): e0168726-null. (Review) Full Text
  - O'Connor, C. "HFSA President's Paper(Accepted)." Journal of Cardiac Failure (January 1, 2017). Full Text
  - O'Connor, CM. "Developing Breakthrough Drugs for Heart Failure: Lessons Learned From the Cystic Fibrosis Experience." Jacc. Heart Failure 5, no. 1 (January 2017): 71-72. Full Text
  - Sherwood, A, Blumenthal, JA, Koch, GG, Hoffman, BM, Watkins, LL, Smith, PJ, O'Connor, CM, Adams, KF, Rogers, JG, Sueta, C, Chang, PP, Johnson, KS, Schwartz, J, and Hinderliter, AL. "Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial." Circulation. Heart Failure 10, no. 1 (January 2017). Full Text
  - Streng, KW, Ter Maaten, JM, Cleland, JG, O'Connor, CM, Davison, BA, Metra, M, Givertz, MM, Teerlink, JR, Ponikowski, P, Bloomfield, DM, Dittrich, HC, Hillege, HL, van Veldhuisen, DJ, Voors, AA, and van der Meer, P. "Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure." Circulation. Heart failure 10, no. 1 (January 2017). Full Text
  - Tromp, J, Ter Maaten, JM, Damman, K, O'Connor, CM, Metra, M, Dittrich, HC, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JGF, Givertz, MM, Bloomfield, DM, van der Wal, MHL, Jaarsma, T, van Veldhuisen, DJ, Hillege, HL, Voors, AA, and van der Meer, P. "Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials)." The American Journal of Cardiology 119, no. 2 (January 2017): 290-296. Full Text
  - Verma, AK, Schulte, PJ, Bittner, V, Keteyian, SJ, Fleg, JL, Piña, IL, Swank, AM, Fitz-Gerald, M, Ellis, SJ, Kraus, WE, Whellan, DJ, O'Connor, CM, and Mentz, RJ. "Socioeconomic and partner status in chronic heart failure: Relationship to exercise capacity, quality of life, and clinical outcomes." American heart journal 183 (January 2017): 54-61. Full Text
  - O'Connor, CM. "Not Your Mother's FDA." Jacc. Heart Failure 4, no. 12 (December 2016): 978-null. Full Text
  - Vegter, EL, Schmitter, D, Hagemeijer, Y, Ovchinnikova, ES, van der Harst, P, Teerlink, JR, O'Connor, CM, Metra, M, Davison, BA, Bloomfield, D, Cotter, G, Cleland, JG, Givertz, MM, Ponikowski, P, van Veldhuisen, DJ, van der Meer, P, Berezikov, E, Voors, AA, and Khan, MAF. "Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure." International journal of cardiology 224 (December 2016): 231-239. Full Text
  - Ambrosy, AP, Cerbin, LP, Armstrong, PW, Butler, J, Coles, A, DeVore, AD, Dunlap, ME, Ezekowitz, JA, Felker, GM, Fudim, M, Greene, SJ, Hernandez, AF, O'Connor, CM, Schulte, P, Starling, RC, Teerlink, JR, Voors, AA, and Mentz, RJ. "Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From ASCEND-HF." Jacc. Heart Failure (November 30, 2016). Full Text
  - Demissei, BG, Postmus, D, Liu, LCY, Cleland, JG, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, BA, Edwards, C, Givertz, MM, Bloomfield, DM, Dittrich, HC, Voors, AA, and Hillege, HL. "Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial." International Journal of Cardiology 223 (November 2016): 967-975. Full Text
  - O'Connor, CM. "Peer Review of Peer Review: Somewhere Over the Rainbow." Jacc. Heart Failure 4, no. 11 (November 2016): 907-908. Full Text
  - Cotter, G, Davison, BA, Milo, O, Bourge, RC, Cleland, JGF, Jondeau, G, Krum, H, O'Connor, CM, Metra, M, Parker, JD, Torre-Amione, G, van Veldhuisen, DJ, Kobrin, I, Rainisio, M, Senger, S, Edwards, C, McMurray, JJV, Teerlink, JR, and VERITAS Investigators, . "Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS." Journal of cardiac failure 22, no. 10 (October 2016): 815-822. Full Text
  - O'Connor, CM. "The International Olympic Games: Heart Teams and Heart Failure." Jacc. Heart Failure 4, no. 10 (October 2016): 826-827. Full Text
  - Parikh, KS, Coles, A, Schulte, PJ, Kraus, WE, Fleg, JL, Keteyian, SJ, Piña, IL, Fiuzat, M, Whellan, DJ, O'Connor, CM, and Mentz, RJ. "Relation of Angina Pectoris to Outcomes, Quality of Life, and Response to Exercise Training in Patients With Chronic Heart Failure (from HF-ACTION)." The American Journal of Cardiology 118, no. 8 (October 2016): 1211-1216. Full Text
  - Tromp, J, Meyer, S, Mentz, RJ, O'Connor, CM, Metra, M, Dittrich, HC, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JGF, Givertz, MM, Bloomfield, DM, van Veldhuisen, DJ, Hillege, HL, Voors, AA, and van der Meer, P. "Acute heart failure in the young: Clinical characteristics and biomarker profiles." International Journal of Cardiology 221 (October 2016): 1067-1072. Full Text
  - Greene, SJ, Hernandez, AF, Sun, J-L, Metra, M, Butler, J, Ambrosy, AP, Ezekowitz, JA, Starling, RC, Teerlink, JR, Schulte, PJ, Voors, AA, Armstrong, PW, O'Connor, CM, and Mentz, RJ. "Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure)." Circulation. Heart Failure 9, no. 9 (September 2016). Full Text
  - Luo, N, Rogers, JG, Dodson, GC, Patel, CB, Galanos, AN, Milano, CA, O'Connor, CM, and Mentz, RJ. "Usefulness of Palliative Care to Complement the Management of Patients on Left Ventricular Assist Devices." The American Journal of Cardiology 118, no. 5 (September 2016): 733-738. (Review) Full Text
  - O’Connor, CM. "The Mentor’s Mentor." JACC: Heart Failure 4, no. 9 (September 2016): 759-759. Full Text
  - Davison, BA, Metra, M, Senger, S, Edwards, C, Milo, O, Bloomfield, DM, Cleland, JG, Dittrich, HC, Givertz, MM, O'Connor, CM, Massie, BM, Ponikowski, P, Teerlink, JR, Voors, AA, and Cotter, G. "Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality." European Journal of Heart Failure 18, no. 8 (August 2016): 1041-1050. Full Text
  - Kelly, JP, Cooper, LB, Gallup, D, Anstrom, KJ, Chen, HH, Redfield, MM, O'Connor, CM, Mentz, RJ, Hernanadez, AF, and Felker, GM. "Implications of Using Different Definitions on Outcomes in Worsening Heart Failure." Circulation. Heart Failure 9, no. 8 (August 2016). Full Text
  - Kelly, JP, Dunning, A, Schulte, PJ, Fiuzat, M, Leifer, ES, Fleg, JL, Cooper, LS, Keteyian, SJ, Kitzman, DW, Pina, IL, Kraus, WE, Whellan, DJ, O'Connor, CM, and Mentz, RJ. "Statins and Exercise Training Response in Heart Failure Patients: Insights From HF-ACTION." Jacc. Heart Failure 4, no. 8 (August 2016): 617-624. Full Text
  - O’Connor, CM. "Can Academic Cardiology Divisions Survive?." JACC: Heart Failure 4, no. 8 (August 2016): 687-688. Full Text
  - Paine, NJ, Hinderliter, AL, Blumenthal, JA, Adams, KF, Sueta, CA, Chang, PP, O'Connor, CM, and Sherwood, A. "Reactive hyperemia is associated with adverse clinical outcomes in heart failure." American Heart Journal 178 (August 2016): 108-114. Full Text
  - Ter Maaten, JM, Damman, K, Hanberg, JS, Givertz, MM, Metra, M, O'Connor, CM, Teerlink, JR, Ponikowski, P, Cotter, G, Davison, B, Cleland, JG, Bloomfield, DM, Hillege, HL, van Veldhuisen, DJ, Voors, AA, and Testani, JM. "Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure." Circulation. Heart Failure 9, no. 8 (August 2016). Full Text
  - Banks, AZ, Mentz, RJ, Stebbins, A, Mikus, CR, Schulte, PJ, Fleg, JL, Cooper, LS, Leifer, ES, Badenhop, DT, Keteyian, SJ, Piña, IL, Kitzman, DW, Fiuzat, M, Whellan, DJ, Kraus, WE, and O'Connor, CM. "Response to Exercise Training and Outcomes in Patients With Heart Failure and Diabetes Mellitus: Insights From the HF-ACTION Trial." Journal of Cardiac Failure 22, no. 7 (July 2016): 485-491. Full Text
  - Biegus, J, Hillege, HL, Postmus, D, Valente, MAE, Bloomfield, DM, Cleland, JGF, Cotter, G, Davison, BA, Dittrich, HC, Fiuzat, M, Givertz, MM, Massie, BM, Metra, M, Teerlink, JR, Voors, AA, O'Connor, CM, and Ponikowski, P. "Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study." European Journal of Heart Failure 18, no. 7 (July 2016): 830-839. Full Text
  - Denardo, SJ, Vock, DM, Schmalfuss, CM, Young, GD, Tcheng, JE, and O'Connor, CM. "Baseline Hemodynamics and Response to Contrast Media During Diagnostic Cardiac Catheterization Predict Adverse Events in Heart Failure Patients." Circulation. Heart failure 9, no. 7 (July 2016). Full Text
  - O’Connor, CM. "The Year in Heart Failure Review 2015 to 2016." JACC: Heart Failure 4, no. 7 (July 2016): 603-604. Full Text
  - Emmens, JE, Ter Maaten, JM, Matsue, Y, Metra, M, O'Connor, CM, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JG, Givertz, MM, Bloomfield, DM, Dittrich, HC, Todd, J, van Veldhuisen, DJ, Hillege, HL, Damman, K, van der Meer, P, and Voors, AA. "Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome." European Journal of Heart Failure 18, no. 6 (June 2016): 641-649. Full Text
  - Metra, M, Mentz, RJ, Hernandez, AF, Heizer, GM, Armstrong, PW, Clausell, N, Corbalan, R, Costanzo, MR, Dickstein, K, Dunlap, ME, Ezekowitz, JA, Howlett, JG, Komajda, M, Krum, H, Lombardi, C, Fonarow, GC, McMurray, JJV, Nieminen, MS, Swedberg, K, Voors, AA, Starling, RC, Teerlink, JR, and O'Connor, CM. "Geographic Differences in Patients in a Global Acute Heart Failure Clinical Trial (from the ASCEND-HF Trial)." The American journal of cardiology 117, no. 11 (June 2016): 1771-1778. Full Text
  - O'Connor, CM. "Social Media: Can It Reduce Heart Failure Events?." JACC: Heart Failure 4, no. 6 (June 1, 2016): 514-515. Full Text
  - Reeves, GR, Whellan, DJ, Patel, MJ, O'Connor, CM, Duncan, P, Eggebeen, JD, Morgan, TM, Hewston, LA, Pastva, AM, and Kitzman, DW. "Comparison of Frequency of Frailty and Severely Impaired Physical Function in Patients ≥60 Years Hospitalized With Acute Decompensated Heart Failure Versus Chronic Stable Heart Failure With Reduced and Preserved Left Ventricular Ejection Fraction." The American journal of cardiology 117, no. 12 (June 2016): 1953-1958. Full Text
  - Ter Maaten, JM, Valente, MAE, Damman, K, Cleland, JG, Givertz, MM, Metra, M, O'Connor, CM, Teerlink, JR, Ponikowski, P, Bloomfield, DM, Cotter, G, Davison, B, Subacius, H, van Veldhuisen, DJ, van der Meer, P, Hillege, HL, Gheorghiade, M, and Voors, AA. "Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure." Circulation. Heart Failure 9, no. 6 (June 2016). Full Text
  - Whellan, DJ, Stebbins, A, Hernandez, AF, Ezekowitz, JA, McMurray, JJV, Mather, PJ, Hasselblad, V, and O'Connor, CM. "Dichotomous Relationship Between Age and 30-Day Death or Rehospitalization in Heart Failure Patients Admitted With Acute Decompensated Heart Failure: Results From the ASCEND-HF Trial." Journal of cardiac failure 22, no. 6 (June 2016): 409-416. Full Text
  - Wong, YW, Mentz, RJ, Felker, GM, Ezekowitz, J, Pieper, K, Heizer, G, Hasselblad, V, Metra, M, O'Connor, CM, Armstrong, PW, Starling, RC, and Hernandez, AF. "Nesiritide in patients hospitalized for acute heart failure: does timing matter? Implication for future acute heart failure trials." European journal of heart failure 18, no. 6 (June 2016): 684-692. Full Text
  - Navarese, EP, Kolodziejczak, M, Kereiakes, DJ, Tantry, US, O'Connor, C, and Gurbel, PA. "Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review." Annals of Internal Medicine 164, no. 9 (May 2016): 600-607. (Review) Full Text
  - O'Connor, CM, Fiuzat, M, and Lindenfeld, J. "Are We Really in Love With Old Therapies?." JACC. Heart failure (April 12, 2016). Full Text
  - Garber, AM, Mentz, RJ, Al-Khalidi, HR, Shaw, LK, Fiuzat, M, O'Connor, CM, and Velazquez, EJ. "Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction." Journal of thrombosis and thrombolysis 41, no. 3 (April 2016): 365-373. Full Text
  - O'Connor, CM. "Why Negative Trials Are Positive for Heart Failure Patients." JACC. Heart failure 4, no. 4 (April 2016): 329-330. Full Text
  - Ovchinnikova, ES, Schmitter, D, Vegter, EL, Ter Maaten, JM, Valente, MAE, Liu, LCY, van der Harst, P, Pinto, YM, de Boer, RA, Meyer, S, Teerlink, JR, O'Connor, CM, Metra, M, Davison, BA, Bloomfield, DM, Cotter, G, Cleland, JG, Mebazaa, A, Laribi, S, Givertz, MM, Ponikowski, P, van der Meer, P, van Veldhuisen, DJ, Voors, AA, and Berezikov, E. "Signature of circulating microRNAs in patients with acute heart failure." European Journal of Heart Failure 18, no. 4 (April 2016): 414-423. Full Text
  - Rosendorff, C, and Writing Committee, . "Treatment of Hypertension in Patients with Coronary Artery Disease. A Case-Based Summary of the 2015 AHA/ACC/ASH Scientific Statement." The American journal of medicine 129, no. 4 (April 2016): 372-378. (Review) Full Text
  - Samsky, MD, Dunning, A, DeVore, AD, Schulte, PJ, Starling, RC, Tang, WHW, Armstrong, PW, Ezekowitz, JA, Butler, J, McMurray, JJ, Teerlink, JR, Voors, AA, Metra, M, Mentz, RJ, O'Connor, CM, Patel, CB, and Hernandez, AF. "Liver function tests in patients with acute heart failure and associated outcomes: insights from ASCEND-HF." European journal of heart failure 18, no. 4 (April 2016): 424-432. Full Text
  - Ezekowitz, JA, Podder, M, Hernandez, AF, Armstrong, PW, Starling, RC, O'Connor, CM, and Califf, RM. "Arrival by ambulance in acute heart failure: insights into the mode of presentation from Acute Studies of Nesiritide in Decompensated Heart Failure (ASCEND-HF)." BMJ open 6, no. 3 (March 17, 2016): e010201-. Full Text
  - Ambrosy, AP, Hernandez, AF, Armstrong, PW, Butler, J, Dunning, A, Ezekowitz, JA, Felker, GM, Greene, SJ, Kaul, P, McMurray, JJ, Metra, M, O'Connor, CM, Reed, SD, Schulte, PJ, Starling, RC, Tang, WHW, Voors, AA, and Mentz, RJ. "The clinical course of health status and association with outcomes in patients hospitalized for heart failure: insights from ASCEND-HF." European Journal of Heart Failure 18, no. 3 (March 2016): 306-313. Full Text
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  - Demissei, BG, Valente, MAE, Cleland, JG, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Givertz, MM, Bloomfield, DM, Dittrich, H, van der Meer, P, van Veldhuisen, DJ, Hillege, HL, and Voors, AA. "Optimizing clinical use of biomarkers in high-risk acute heart failure patients." European Journal of Heart Failure 18, no. 3 (March 2016): 269-280. Full Text
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  - O'Connor, CM. "I Lost a Friend From HFpEF: William Anlyan, MD, Chancellor Emeritus and Duke University Trustee." JACC. Heart failure 4, no. 3 (March 2016): 230-231. Full Text
  - Perez, AL, Grodin, JL, Wu, Y, Hernandez, AF, Butler, J, Metra, M, Felker, GM, Voors, AA, McMurray, JJ, Armstrong, PW, Starling, RC, O'Connor, CM, and Tang, WHW. "Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy." European Journal of Heart Failure 18, no. 3 (March 2016): 290-297. Full Text
  - Demissei, BG, Cleland, JG, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Davison, B, Givertz, MM, Bloomfield, DM, Dittrich, H, van Veldhuisen, DJ, Hillege, HL, Voors, AA, and Cotter, G. "Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients." International journal of cardiology 204 (February 2016): 164-171. Full Text
  - Fiuzat, M, Wojdyla, D, Pina, I, Adams, K, Whellan, D, and O'Connor, CM. "Heart Rate or Beta-Blocker Dose? Association With Outcomes in Ambulatory Heart Failure Patients With Systolic Dysfunction: Results From the HF-ACTION Trial." Jacc. Heart Failure 4, no. 2 (February 2016): 109-115. Full Text
  - Keteyian, SJ, Patel, M, Kraus, WE, Brawner, CA, McConnell, TR, Piña, IL, Leifer, ES, Fleg, JL, Blackburn, G, Fonarow, GC, Chase, PJ, Piner, L, Vest, M, O'Connor, CM, Ehrman, JK, Walsh, MN, Ewald, G, Bensimhon, D, Russell, SD, and HF-ACTION Investigators, . "Variables Measured During Cardiopulmonary Exercise Testing as Predictors of Mortality in Chronic Systolic Heart Failure." Journal of the American College of Cardiology 67, no. 7 (February 2016): 780-789. Full Text
  - Mark, DB, and O'Connor, CM. "When Business and Science Clash, How Can We Avoid Harming Patients?: The Case of AVOID-HF." JACC. Heart failure 4, no. 2 (February 2016): 106-108. Full Text
  - Mentz, RJ, Hasselblad, V, DeVore, AD, Metra, M, Voors, AA, Armstrong, PW, Ezekowitz, JA, Tang, WHW, Schulte, PJ, Anstrom, KJ, Hernandez, AF, Velazquez, EJ, and O'Connor, CM. "Torsemide Versus Furosemide in Patients With Acute Heart Failure (from the ASCEND-HF Trial)." The American Journal of Cardiology 117, no. 3 (February 2016): 404-411. Full Text
  - O'Connor, CM. "Death of the Heart Failure Clinical Investigator: Molecules and Receptors Win Nobel Prizes, Clinical Investigation Improves Survival." JACC. Heart failure 4, no. 2 (February 2016): 162-163. Full Text
  - ter Maaten, JM, Valente, MAE, Metra, M, Bruno, N, O'Connor, CM, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JG, Givertz, MM, Bloomfield, DM, Dittrich, HC, van Veldhuisen, DJ, Hillege, HL, Damman, K, and Voors, AA. "A combined clinical and biomarker approach to predict diuretic response in acute heart failure." Clinical Research in Cardiology : Official Journal of the German Cardiac Society 105, no. 2 (February 2016): 145-153. Full Text
  - Ahmad, T, Desai, N, Wilson, F, Schulte, P, Dunning, A, Jacoby, D, Allen, L, Fiuzat, M, Rogers, J, Felker, GM, O'Connor, C, and Patel, CB. "Clinical Implications of Cluster Analysis-Based Classification of Acute Decompensated Heart Failure and Correlation with Bedside Hemodynamic Profiles." Plos One 11, no. 2 (January 2016): e0145881-null. Full Text
  - Ahmad, T, Kelly, JP, McGarrah, RW, Hellkamp, AS, Fiuzat, M, Testani, JM, Wang, TS, Verma, A, Samsky, MD, Donahue, MP, Ilkayeva, OR, Bowles, DE, Patel, CB, Milano, CA, Rogers, JG, Felker, GM, O'Connor, CM, Shah, SH, and Kraus, WE. "Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support." Journal of the American College of Cardiology 67, no. 3 (January 2016): 291-299. Full Text
  - Bruno, N, ter Maaten, JM, Ovchinnikova, ES, Vegter, EL, Valente, MAE, van der Meer, P, de Boer, RA, van der Harst, P, Schmitter, D, Metra, M, O'Connor, CM, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JG, Givertz, MM, Bloomfield, DM, Dittrich, HC, Pinto, YM, van Veldhuisen, DJ, Hillege, HL, Berezikov, E, and Voors, AA. "MicroRNAs relate to early worsening of renal function in patients with acute heart failure." International journal of cardiology 203 (January 2016): 564-569. Full Text
  - Mentz, R, and O'Connor, C. "Pathophysiology and clinical evaluation of acute heart failure." Nature Reviews Cardiology 13, no. 1 (January 1, 2016): 28-35. Full Text Link to Item
  - O'Connor, CM. "Why Dr. Robert Califf's Nomination for Commissioner of the Food and Drug Administration Is Good for Heart Failure Patients." JACC. Heart failure 4, no. 1 (January 2016): 90-91. Full Text
  - Tang, WHW, Wu, Y, Grodin, JL, Hsu, AP, Hernandez, AF, Butler, J, Metra, M, Voors, AA, Felker, GM, Troughton, RW, Mills, RM, McMurray, JJ, Armstrong, PW, O'Connor, CM, and Starling, RC. "Prognostic Value of Baseline and Changes in Circulating Soluble ST2 Levels and the Effects of Nesiritide in Acute Decompensated Heart Failure." JACC. Heart failure 4, no. 1 (January 2016): 68-77. Full Text
  - Brunner-La Rocca, H-P, Eurlings, L, Richards, AM, Januzzi, JL, Pfisterer, ME, Dahlström, U, Pinto, YM, Karlström, P, Erntell, H, Berger, R, Persson, H, O'Connor, CM, Moertl, D, Gaggin, HK, Frampton, CM, Nicholls, MG, and Troughton, RW. "Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials." European Journal of Heart Failure 17, no. 12 (December 2015): 1252-1261. Full Text
  - O'Connor, CM. "Heart Failure "End Result Cards": Solid B." JACC. Heart failure 3, no. 12 (December 2015): 1001-1002. Full Text
  - Cooper, LB, Mentz, RJ, Sun, J-L, Schulte, PJ, Fleg, JL, Cooper, LS, Piña, IL, Leifer, ES, Kraus, WE, Whellan, DJ, Keteyian, SJ, and O'Connor, CM. "Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)." Circulation. Heart Failure 8, no. 6 (November 2015): 1044-1051. Full Text
  - O'Connor, CM. "Bundle Up for Value-Based Heart Failure Care." JACC. Heart failure 3, no. 11 (November 2015): 931-932. Full Text
  - Grodin, JL, Perez, AL, Wu, Y, Hernandez, AF, Butler, J, Metra, M, Felker, GM, Voors, AA, McMurray, JJ, Armstrong, PW, Califf, RM, Starling, RC, O'Connor, CM, and Tang, WHW. "Circulating Kidney Injury Molecule-1 Levels in Acute Heart Failure: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure)." JACC. Heart failure 3, no. 10 (October 2015): 777-785. Full Text
  - O'Connor, CM. "Physician-Leaders: A Call for Cardiovascular Specialists to Step Up." JACC. Heart failure 3, no. 10 (October 2015): 843-844. Full Text
  - Samad, Z, Shaw, LK, Phelan, M, Ersboll, M, Risum, N, Al-Khalidi, HR, Glower, DD, Milano, CA, Alexander, JH, O'Connor, CM, Wang, A, and Velazquez, EJ. "Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction." European Heart Journal 36, no. 40 (October 2015): 2733-2741. Full Text
  - Mentz, RJ, Velazquez, EJ, Metra, M, McKendry, C, Chiswell, K, Fiuzat, M, Givertz, MM, Voors, AA, Teerlink, JR, and O'Connor, CM. "Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial." Future Cardiology 11, no. 5 (September 25, 2015): 585-595. Full Text
  - Felker, GM, Mentz, RJ, Adams, KF, Cole, RT, Egnaczyk, GF, Patel, CB, Fiuzat, M, Gregory, D, Wedge, P, O'Connor, CM, Udelson, JE, and Konstam, MA. "Tolvaptan in Patients Hospitalized With Acute Heart Failure: Rationale and Design of the TACTICS and the SECRET of CHF Trials." Circulation. Heart Failure 8, no. 5 (September 2015): 997-1005. (Review) Full Text
  - O'Connor, CM. "What Is a Life Worth?: A Tribute to Dr. William Little, a Pioneer in the Understanding of Heart Failure With Preserved Ejection Fraction." JACC. Heart failure 3, no. 9 (September 2015): 734-735. Full Text
  - Xiong, GL, Prybol, K, Boyle, SH, Hall, R, Streilein, RD, Steffens, DC, Krishnan, R, Rogers, JG, O'Connor, CM, Jiang, W, and SADHART-CHF Investigators, . "Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study." Psychosomatic Medicine 77, no. 7 (September 2015): 808-815. Full Text
  - Abualnaja, S, Podder, M, Hernandez, AF, McMurray, JJV, Starling, RC, O'Connor, CM, Califf, RM, Armstrong, PW, and Ezekowitz, JA. "Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) Trial." Journal of the American Heart Association 4, no. 8 (August 24, 2015): e002092-null. Full Text
  - Dardas, T, Li, Y, Reed, SD, O'Connor, CM, Whellan, DJ, Ellis, SJ, Schulman, KA, Kraus, WE, Forman, DE, and Levy, WC. "Incremental and independent value of cardiopulmonary exercise test measures and the Seattle Heart Failure Model for prediction of risk in patients with heart failure." The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 34, no. 8 (August 2015): 1017-1023. Full Text
  - Farzaneh-Far, A, Shaw, LK, Dunning, A, Oldan, JD, O'Connor, CM, and Borges-Neto, S. "Comparison of the prognostic value of regadenoson and adenosine myocardial perfusion imaging." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 22, no. 4 (August 2015): 600-607. Full Text
  - Hess, PL, Shaw, LK, Vemulapalli, S, Pagnanelli, R, O'Connor, CM, and Borges-Neto, S. "An alternative method to examine the predictive value of mechanical dyssynchrony." Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 22, no. 4 (August 2015): 686-689. Full Text
  - Kelly, JP, Mentz, RJ, Hasselblad, V, Ezekowitz, JA, Armstrong, PW, Zannad, F, Felker, GM, Califf, RM, O'Connor, CM, and Hernandez, AF. "Worsening heart failure during hospitalization for acute heart failure: Insights from the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF)." American Heart Journal 170, no. 2 (August 2015): 298-305. Full Text
  - Khazanie, P, Heizer, GM, Hasselblad, V, Armstrong, PW, Califf, RM, Ezekowitz, J, Dickstein, K, Levy, WC, McMurray, JJV, Metra, M, Tang, WHW, Teerlink, JR, Voors, AA, O'Connor, CM, Hernandez, AF, and Starling, R. "Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models." American Heart Journal 170, no. 2 (August 2015): 290-297. Full Text
  - O'Connor, CM, and Ahmad, T. "The Role of Sodium and Chloride in Heart Failure: Does It Take Two to Tango?." Journal of the American College of Cardiology 66, no. 6 (August 2015): 667-669. Full Text
  - O'Connor, CM. "The Globalization of Heart Failure Research." JACC. Heart failure 3, no. 8 (August 2015): 657-658. Full Text
  - ter Maaten, JM, Dunning, AM, Valente, MAE, Damman, K, Ezekowitz, JA, Califf, RM, Starling, RC, van der Meer, P, O'Connor, CM, Schulte, PJ, Testani, JM, Hernandez, AF, Tang, WHW, and Voors, AA. "Diuretic response in acute heart failure-an analysis from ASCEND-HF." American Heart Journal 170, no. 2 (August 2015): 313-321. Full Text
  - Ahmad, T, O'Brien, EC, Schulte, PJ, Stevens, SR, Fiuzat, M, Kitzman, DW, Adams, KF, Kraus, WE, Piña, IL, Donahue, MP, Zannad, F, Whellan, DJ, O'Connor, CM, and Felker, GM. "Evaluation of the Incremental Prognostic Utility of Increasingly Complex Testing in Chronic Heart Failure." Circulation. Heart Failure 8, no. 4 (July 2015): 709-716. Full Text
  - Harinstein, ME, Butler, J, Greene, SJ, Fonarow, GC, Stockbridge, NL, O'Connor, CM, Pfeffer, MA, Mehra, MR, Solomon, SD, Yancy, CW, Fiuzat, M, Mentz, RJ, Collins, SP, McMurray, JJV, Vaduganathan, M, Dunnmon, PM, Rosano, GMC, Dinh, W, Misselwitz, F, Bonow, RO, and Gheorghiade, M. "Site selection for heart failure clinical trials in the USA." Heart failure reviews 20, no. 4 (July 2015): 375-383. Full Text
  - Mentz, RJ, Metra, M, Cotter, G, Milo, O, McKendry, C, Chiswell, K, Davison, BA, Cleland, JGF, Bloomfield, DM, Dittrich, HC, Fiuzat, M, Ponikowski, P, Givertz, MM, Voors, AA, Teerlink, JR, and O'Connor, CM. "Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial." European Journal of Heart Failure 17, no. 7 (July 2015): 697-706. Full Text
  - O'Connor, CM. "RESPONSE: Are We Committed to Training Fellows in Clinical Investigation?." Journal of the American College of Cardiology 66, no. 3 (July 2015): 326-327.
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  - Taylor, RS, Piepoli, MF, Smart, N, Coats, AJS, Ellis, S, Dalal, H, O'Connor, CM, Warren, FC, Whellan, D, and Ciani, O. "Erratum: Corrigendum to exercise training for chronic heart failure (ExTraMATCH II): Protocol for an individual participant data meta-analysis (Int J Cardiol. (2014) 174:3 (683-687) DOI: http://dx.doi.org/10.1016/j.ijcard.2014.04.203)." International Journal of Cardiology 193 (June 11, 2015): 93-null. Full Text
  - Boyle, SH, Matson, WR, Velazquez, EJ, Samad, Z, Williams, RB, Sharma, S, Thomas, B, Wilson, JL, O'Connor, C, and Jiang, W. "Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction." Metabolomics : Official Journal of the Metabolomic Society 11, no. 3 (June 2015): 571-582. Full Text
  - O'Connor, CM. "Time for Recognition." JACC. Heart failure 3, no. 6 (June 2015): 508-509. Full Text
  - Rosendorff, C, Lackland, DT, Allison, M, Aronow, WS, Black, HR, Blumenthal, RS, Cannon, CP, de Lemos, JA, Elliott, WJ, Findeiss, L, Gersh, BJ, Gore, JM, Levy, D, Long, JB, O'Connor, CM, O'Gara, PT, Ogedegbe, G, Oparil, S, White, WB, American Heart Association, American College of Cardiology, and and American Society of Hypertension, . "Treatment of hypertension in patients with coronary artery disease: a scientific statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension." Hypertension (Dallas, Tex. : 1979) 65, no. 6 (June 2015): 1372-1407. (Review) Full Text
  - Rosendorff, C, Lackland, DT, Allison, M, Aronow, WS, Black, HR, Blumenthal, RS, Cannon, CP, de Lemos, JA, Elliott, WJ, Findeiss, L, Gersh, BJ, Gore, JM, Levy, D, Long, JB, O'Connor, CM, O'Gara, PT, Ogedegbe, O, Oparil, S, White, WB, American Heart Association, American College of Cardiology, and and American Society of Hypertension, . "Treatment of hypertension in patients with coronary artery disease: A scientific statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension." Journal of the American Society of Hypertension : JASH 9, no. 6 (June 2015): 453-498. (Review) Full Text
  - Davison, BA, Metra, M, Cotter, G, Massie, BM, Cleland, JGF, Dittrich, HC, Edwards, C, Filippatos, G, Givertz, MM, Greenberg, B, Ponikowski, P, Voors, AA, O'Connor, CM, Teerlink, JR, and PROTECT and RELAX-AHF Executive Committees, . "Worsening Heart Failure Following Admission for Acute Heart Failure: A Pooled Analysis of the PROTECT and RELAX-AHF Studies." JACC. Heart failure 3, no. 5 (May 2015): 395-403. Full Text
  - Givertz, MM, Anstrom, KJ, Redfield, MM, Deswal, A, Haddad, H, Butler, J, Tang, WHW, Dunlap, ME, LeWinter, MM, Mann, DL, Felker, GM, O'Connor, CM, Goldsmith, SR, Ofili, EO, Saltzberg, MT, Margulies, KB, Cappola, TP, Konstam, MA, Semigran, MJ, McNulty, SE, Lee, KL, Shah, MR, Hernandez, AF, and NHLBI Heart Failure Clinical Research Network, . "Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study." Circulation 131, no. 20 (May 2015): 1763-1771. Full Text
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  - Mentz, RJ, Buggey, J, Fiuzat, M, Ersbøll, MK, Schulte, PJ, DeVore, AD, Eisenstein, EL, Anstrom, KJ, OʼConnor, CM, and Velazquez, EJ. "Torsemide versus furosemide in heart failure patients: insights from Duke University Hospital." Journal of Cardiovascular Pharmacology 65, no. 5 (May 2015): 438-443. Full Text Open Access Copy
  - O'Connor, CM. "Medical editors' grand rounds: a discussion of timely topics and editorial emergencies." JACC. Heart failure 3, no. 5 (May 2015): 422-423. Full Text
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  - Rosendorff, C, Lackland, DT, Allison, M, Aronow, WS, Black, HR, Blumenthal, RS, Cannon, CP, de Lemos, JA, Elliott, WJ, Findeiss, L, Gersh, BJ, Gore, JM, Levy, D, Long, JB, O'Connor, CM, O'Gara, PT, Ogedegbe, O, Oparil, S, White, WB, American Heart Association, , American College of Cardiology, , and American Society of Hypertension, . "Treatment of Hypertension in Patients With Coronary Artery Disease: A Scientific Statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension." Journal of the American College of Cardiology 65, no. 18 (May 2015): 1998-2038. Full Text
  - Jiang, W, Boyle, SH, Ortel, TL, Samad, Z, Velazquez, EJ, Harrison, RW, Wilson, J, Kuhn, C, Williams, RB, O'Connor, CM, and Becker, RC. "Platelet aggregation and mental stress induced myocardial ischemia: Results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study." American heart journal 169, no. 4 (April 2015): 496-507.e1. Full Text Open Access Copy
  - Kelly, JP, Mentz, RJ, Mebazaa, A, Voors, AA, Butler, J, Roessig, L, Fiuzat, M, Zannad, F, Pitt, B, O'Connor, CM, and Lam, CSP. "Patient selection in heart failure with preserved ejection fraction clinical trials." Journal of the American College of Cardiology 65, no. 16 (April 2015): 1668-1682. (Review) Full Text
  - O'Connor, CM. "Reading RVUs: How can we meet the informational needs of cardiologists?." JACC. Heart failure 3, no. 4 (April 2015): 340-341. Full Text
  - Whellan, DJ, Kraus, WE, Kitzman, DW, Rooney, B, Keteyian, SJ, Piña, IL, Ellis, SJ, Ghali, JK, Lee, KL, Cooper, LS, and O'Connor, CM. "Authorship in a multicenter clinical trial: The Heart Failure-A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) Authorship and Publication (HAP) scoring system results." American heart journal 169, no. 4 (April 2015): 457-63.e6. (Review) Full Text
  - Buggey, J, Mentz, RJ, Pitt, B, Eisenstein, EL, Anstrom, KJ, Velazquez, EJ, and O'Connor, CM. "A reappraisal of loop diuretic choice in heart failure patients." American Heart Journal 169, no. 3 (March 2015): 323-333. (Review) Full Text
  - Butler, J, Fonarow, GC, O'Connor, C, Adams, K, Bonow, RO, Cody, RJ, Collins, SP, Dunnmon, P, Dinh, W, Fiuzat, M, Georgiopoulou, VV, Grant, S, Kim, S-Y, Kupfer, S, Lefkowitz, M, Mentz, RJ, Misselwitz, F, Pitt, B, Roessig, L, Schelbert, E, Shah, M, Solomon, S, Stockbridge, N, Yancy, C, and Gheorghiade, M. "Improving cardiovascular clinical trials conduct in the United States: recommendation from clinicians, researchers, sponsors, and regulators." American heart journal 169, no. 3 (March 2015): 305-314. Full Text
  - Metra, M, Cotter, G, El-Khorazaty, J, Davison, BA, Milo, O, Carubelli, V, Bourge, RC, Cleland, JG, Jondeau, G, Krum, H, O'Connor, CM, Parker, JD, Torre-Amione, G, van Veldhuisen, DJ, Rainisio, M, Kobrin, I, McMurray, JJ, and Teerlink, JR. "Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study." Journal of Cardiac Failure 21, no. 3 (March 2015): 179-188. Full Text
  - O'Connor, CM. "Hop, skip, and jump: do we need phase II cardiovascular clinical trials?." JACC. Heart failure 3, no. 3 (March 2015): 273-274. Full Text
  - Mentz, RJ, Stevens, SR, DeVore, AD, Lala, A, Vader, JM, AbouEzzeddine, OF, Khazanie, P, Redfield, MM, Stevenson, LW, O'Connor, CM, Goldsmith, SR, Bart, BA, Anstrom, KJ, Hernandez, AF, Braunwald, E, and Felker, GM. "Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure." JACC. Heart failure 3, no. 2 (February 2015): 97-107. Full Text Open Access Copy
  - O'Connor, CM. "War and peace: the role of medical journals in the discussion of conflict." JACC. Heart failure 3, no. 2 (February 2015): 192-. Full Text
  - Dardas, T, Li, Y, Reed, SD, O'Connor, CM, Whellan, DJ, Ellis, SJ, Schulman, KA, Kraus, WE, Forman, DE, and Levy, WC. "Incremental and independent value of cardiopulmonary exercise test measures and the Seattle Heart Failure Model for prediction of risk in patients with heart failure." Journal of Heart and Lung Transplantation 34, no. 8 (2015): 1017-1023. Full Text
  - Devore, AD, Hasselblad, V, Mentz, RJ, O'Connor, CM, Armstrong, PW, McMurray, JJ, Ezekowitz, JA, Tang, WHW, Starling, RC, Voors, AA, Califf, RM, and Hernandez, AF. "Loop diuretic dose adjustments after a hospitalization for heart failure: Insights from ASCEND-HF." European Journal of Heart Failure 17, no. 3 (January 1, 2015): 340-346. Full Text
  - Fiuzat, M, Georgiopoulou, VV, Grant, S, Kim, SY, Kupfer, S, Lefkowitz, M, Mentz, RJ, Misselwitz, F, Pitt, B, Roessig, L, Schelbert, E, Shah, M, Solomon, S, Stockbridge, N, Yancy, C, and Gheorghiade, M. "Improving cardiovascular clinical trials conduct in the United States: Recommendation from clinicians, researchers, sponsors, and regulators." American Heart Journal 169, no. 3 (January 1, 2015): 305-314. Full Text
  - Jiang, W, Boyle, SH, Ortel, TL, Samad, Z, Velazquez, EJ, Harrison, RW, Wilson, J, Kuhn, C, Williams, RB, O'Connor, CM, and Becker, RC. "Platelet aggregation and mental stress induced myocardial ischemia: Results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study." American Heart Journal 169, no. 4 (January 1, 2015): 496-507.e1. Full Text
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  - Mentz, RJ, Schulte, PJ, Fleg, JL, Fiuzat, M, Kraus, WE, Piña, IL, Keteyian, SJ, Kitzman, DW, Whellan, DJ, Ellis, SJ, and O'Connor, CM. "Clinical characteristics, response to exercise training, and outcomes in patients with heart failure and chronic obstructive pulmonary disease: findings from Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION)." American Heart Journal 165, no. 2 (February 2013): 193-199. Full Text
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  - Mccullough, PA, Barnard, D, Clare, R, Ellis, SJ, Fleg, JL, Fonarow, GC, Franklin, BA, Kilpatrick, RD, Kitzman, DW, O'Connor, CM, Piña, IL, Thadani, U, Thohan, V, and Whellan, DJ. "Anemia and associated clinical outcomes in patients with heart failure due to reduced left ventricular systolic function." Clinical Cardiology 36, no. 10 (2013): 611-620. Full Text
  - Mentz, RJ, Allen, BD, Kwasny, MJ, Konstam, MA, Udelson, JE, Ambrosy, AP, Fought, AJ, Vaduganathan, M, O'Connor, CM, Zannad, F, Maggioni, AP, Swedberg, K, Bonow, RO, and Gheorghiade, M. "Influence of documented history of coronary artery disease on outcomes in patients admitted for worsening heart failure with reduced ejection fraction in the EVEREST trial." Eur J Heart Fail 15, no. 1 (January 2013): 61-68. Full Text Link to Item
  - Mentz, RJ, Bakris, GL, Waeber, B, McMurray, JJV, Gheorghiade, M, Ruilope, LM, Maggioni, AP, Swedberg, K, Piña, IL, Fiuzat, M, O'Connor, CM, Zannad, F, and Pitt, B. "The past, present and future of renin-angiotensin aldosterone system inhibition." International Journal of Cardiology 167, no. 5 (2013): 1677-1687. Full Text
  - Mentz, RJ, Bittner, V, Schulte, PJ, Fleg, JL, Piña, IL, Keteyian, SJ, Moe, G, Nigam, A, Swank, AM, Onwuanyi, AE, Fitz-Gerald, M, Kao, A, Ellis, SJ, Kraus, WE, Whellan, DJ, and O'Connor, CM. "Race, exercise training, and outcomes in chronic heart failure: Findings from Heart Failure - A Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION)." American Heart Journal 166, no. 3 (2013): 488-495.e1. Full Text
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  - Shukla, A, Curtis, AB, Mehra, MR, Albert, NM, Gheorghiade, M, Heywood, JT, Liu, Y, O'Connor, CM, Reynolds, D, Walsh, MN, Yancy, CW, and Fonarow, GC. "Factors associated with improvement in utilization of cardiac resynchronization therapy in eligible heart failure patients: Findings from IMPROVE HF." PACE - Pacing and Clinical Electrophysiology 36, no. 4 (2013): 433-443. Full Text
  - Wu, AH, Levy, WC, Welch, KB, Neuberg, GW, O'Connor, CM, Carson, PE, Miller, AB, and Ghali, JK. "Association between bilirubin and mode of death in severe systolic heart failure." American Journal of Cardiology 111, no. 8 (2013): 1192-1197. Full Text
  - Zannad, F, Stough, WG, Regnault, V, Gheorghiade, M, Deliargyris, E, Gibson, CM, Agewall, S, Berkowitz, SD, Burton, P, Calvo, G, Goldstein, S, Verheugt, FWA, Koglin, J, and O'Connor, CM. "Is thrombosis a contributor to heart failure pathophysiology? Possible mechanisms, therapeutic opportunities, and clinical investigation challenges." International Journal of Cardiology 167, no. 5 (2013): 1772-1782. Full Text
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  - Mentz, RJ, Chung, MJ, Gheorghiade, M, Pang, PS, Kwasny, MJ, Ambrosy, AP, Vaduganathan, M, O'Connor, CM, Swedberg, K, Zannad, F, Konstam, MA, and Maggioni, AP. "Atrial fibrillation or flutter on initial electrocardiogram is associated with worse outcomes in patients admitted for worsening heart failure with reduced ejection fraction: findings from the EVEREST Trial." American heart journal 164, no. 6 (December 2012): 884-92.e2. Full Text
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  - Ezekowitz, JA, Hu, J, Delgado, D, Hernandez, AF, Kaul, P, Leader, R, Proulx, G, Virani, S, White, M, Zieroth, S, O'Connor, C, Westerhout, CM, and Armstrong, PW. "Acute heart failure: perspectives from a randomized trial and a simultaneous registry." Circulation. Heart Failure 5, no. 6 (November 2012): 735-741. Full Text
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  - Gupta, A, Braunwald, E, McNulty, S, Felker, GM, Gilbert, EM, Alharethi, R, Lee, KL, Anstrom, KJ, Redfield, MM, Goldsmith, SR, O'Connor, CM, Bull, DA, Stehlik, J, and Litwin, SE. "Obesity and the response to intensified diuretic treatment in decompensated heart failure: a DOSE trial substudy." Journal of Cardiac Failure 18, no. 11 (November 2012): 837-844. Full Text
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  - Keteyian, SJ, Leifer, ES, Houston-Miller, N, Kraus, WE, Brawner, CA, O'Connor, CM, Whellan, DJ, Cooper, LS, Fleg, JL, Kitzman, DW, Cohen-Solal, A, Blumenthal, JA, Rendall, DS, Piña, IL, and HF-ACTION Investigators, . "Relation between volume of exercise and clinical outcomes in patients with heart failure." Journal of the American College of Cardiology 60, no. 19 (November 2012): 1899-1905. Full Text
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  - Adams, J, Kuchibhatla, M, Christopher, EJ, Alexander, JD, Clary, GL, Cuffe, MS, Califf, RM, Krishnan, RR, O'Connor, CM, and Jiang, W. "Association of depression and survival in patients with chronic heart failure over 12 Years." Psychosomatics 53, no. 4 (July 2012): 339-346. Full Text
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  - Mentz, RJ, Schmidt, PH, Kwasny, MJ, Ambrosy, AP, O'Connor, CM, Konstam, MA, Zannad, F, Maggioni, AP, Swedberg, K, and Gheorghiade, M. "The impact of chronic obstructive pulmonary disease in patients hospitalized for worsening heart failure with reduced ejection fraction: an analysis of the EVEREST Trial." Journal of cardiac failure 18, no. 7 (July 2012): 515-523. Full Text
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  - Ambrosy, AP, Fonarow, GC, Albert, NM, Curtis, AB, Heywood, JT, Mehra, MR, O'Connor, CM, Reynolds, D, Walsh, MN, Yancy, CW, and Gheorghiade, M. "B-type natriuretic peptide assessment in ambulatory heart failure patients: insights from IMPROVE HF." J Cardiovasc Med (Hagerstown) 13, no. 6 (June 2012): 360-367. Full Text Link to Item
  - O'Connor, CM, Mentz, RJ, Cotter, G, Metra, M, Cleland, JG, Davison, BA, Givertz, MM, Mansoor, GA, Ponikowski, P, Teerlink, JR, Voors, AA, Fiuzat, M, Wojdyla, D, Chiswell, K, and Massie, BM. "The PROTECT in-hospital risk model: 7-day outcome in patients hospitalized with acute heart failure and renal dysfunction." European Journal of Heart Failure 14, no. 6 (June 2012): 605-612. Full Text
  - Mentz, RJ, Fiuzat, M, Kraft, M, Lindenfeld, J, and O'Connor, CM. "Bronchodilators in heart failure patients with COPD: is it time for a clinical trial?." Journal of cardiac failure 18, no. 5 (May 2012): 413-422. (Review) Full Text
  - Mentz, RJ, Fiuzat, M, Shaw, LK, Phillips, HR, Borges-Neto, S, Felker, GM, and O'Connor, CM. "Comparison of Clinical characteristics and long-term outcomes of patients with ischemic cardiomyopathy with versus without angina pectoris (from the Duke Databank for Cardiovascular Disease)." Am J Cardiol 109, no. 9 (May 1, 2012): 1272-1277. Full Text Link to Item
  - Reynolds, D, Albert, NM, Curtis, AB, Gheorghiade, M, Heywood, JT, Mcbride, ML, Inge, PJ, Mehra, MR, O'Connor, CM, Walsh, MN, Yancy, CW, and Fonarow, GC. "Race and improvements in the use of guideline-recommended therapies for patients with heart failure: findings from IMPROVE HF." Journal of the National Medical Association 104, no. 5-6 (May 2012): 287-298. Full Text
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  - Felker, GM, Fiuzat, M, Shaw, LK, Clare, R, Whellan, DJ, Bettari, L, Shirolkar, SC, Donahue, M, Kitzman, DW, Zannad, F, Piña, IL, and O'Connor, CM. "Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study." Circulation. Heart Failure 5, no. 1 (January 2012): 72-78. Full Text
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  - O'Connor, CM, Fiuzat, M, Carson, PE, Anand, IS, Plehn, JF, Gottlieb, SS, Silver, MA, Lindenfeld, J, Miller, AB, White, M, Walsh, R, Nelson, P, Medway, A, Davis, G, Robertson, AD, Port, JD, Carr, J, Murphy, GA, Lazzeroni, LC, Abraham, WT, Liggett, SB, and Bristow, MR. "Combinatorial pharmacogenetic interactions of bucindolol and β1, α2C adrenergic receptor polymorphisms." Plos One 7, no. 10 (January 2012): e44324-null. Full Text
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  - Wilcox, JE, Fonarow, GC, Yancy, CW, Albert, NM, Curtis, AB, Heywood, JT, Inge, PJ, McBride, ML, Mehra, MR, O'Connor, CM, Reynolds, D, Walsh, MN, and Gheorghiade, M. "Factors associated with improvement in ejection fraction in clinical practice among patients with heart failure: findings from IMPROVE HF." American Heart Journal 163, no. 1 (January 2012): 49-56.e2. Full Text
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  - Jones, WS, Patel, MR, Holleran, SA, Harrison, JK, O'Connor, CM, and Phillips, HR. "Trends in the use of diagnostic coronary angiography, percutaneous coronary intervention, and coronary artery bypass graft surgery across North Carolina." American Heart Journal 162, no. 5 (November 1, 2011): 923-937. Full Text
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  - Povsic, TJ, O'Connor, CM, Henry, T, Taussig, A, Kereiakes, DJ, Fortuin, FD, Niederman, A, Schatz, R, Spencer, R, Owens, D, Banks, M, Joseph, D, Roberts, R, Alexander, JH, and Sherman, W. "A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in patients with chronic heart failure after myocardial infarction." American Heart Journal 162, no. 4 (October 2011): 654-662.e1. Full Text
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  - West, R, Liang, L, Fonarow, GC, Kociol, R, Mills, RM, O'Connor, CM, and Hernandez, AF. "Characterization of heart failure patients with preserved ejection fraction: a comparison between ADHERE-US registry and ADHERE-International registry." Eur J Heart Fail 13, no. 9 (September 2011): 945-952. Full Text Link to Item
  - O'Connor, CM, Fiuzat, M, Swedberg, K, Caron, M, Koch, B, Carson, PE, Gattis-Stough, W, Davis, GW, and Bristow, MR. "Influence of global region on outcomes in heart failure β-blocker trials." J Am Coll Cardiol 58, no. 9 (August 23, 2011): 915-922. Full Text Link to Item
  - Jones, WS, Clare, R, Ellis, SJ, Mills, JS, Fischman, DL, Kraus, WE, Whellan, DJ, O'Connor, CM, and Patel, MR. "Effect of peripheral arterial disease on functional and clinical outcomes in patients with heart failure (from HF-ACTION)." Am J Cardiol 108, no. 3 (August 1, 2011): 380-384. Full Text Link to Item
  - Shah, MR, Califf, RM, Nohria, A, Bhapkar, M, Bowers, M, Mancini, DM, Fiuzat, M, Stevenson, LW, and O'Connor, CM. "The STARBRITE trial: a randomized, pilot study of B-type natriuretic peptide-guided therapy in patients with advanced heart failure." Journal of Cardiac Failure 17, no. 8 (August 2011): 613-621. Full Text
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  - O'Connor, CM, Starling, RC, Hernandez, AF, Armstrong, PW, Dickstein, K, Hasselblad, V, Heizer, GM, Komajda, M, Massie, BM, McMurray, JJV, Nieminen, MS, Reist, CJ, Rouleau, JL, Swedberg, K, Adams, KF, Anker, SD, Atar, D, Battler, A, Botero, R, Bohidar, NR, Butler, J, Clausell, N, Corbalán, R, Costanzo, MR, Dahlstrom, U, Deckelbaum, LI, Diaz, R, Dunlap, ME, Ezekowitz, JA, Feldman, D, Felker, GM, Fonarow, GC, Gennevois, D, Gottlieb, SS, Hill, JA, Hollander, JE, Howlett, JG, Hudson, MP, Kociol, RD, Krum, H, Laucevicius, A, Levy, WC, Méndez, GF, Metra, M, Mittal, S, Oh, B-H, Pereira, NL, Ponikowski, P, Tang, WHW, Tanomsup, S, Teerlink, JR, Triposkiadis, F, Troughton, RW, Voors, AA, Whellan, DJ, Zannad, F, and Califf, RM. "Effect of nesiritide in patients with acute decompensated heart failure." The New England Journal of Medicine 365, no. 1 (July 2011): 32-43. Full Text
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  - Metra, M, O'Connor, CM, Davison, BA, Cleland, JGF, Ponikowski, P, Teerlink, JR, Voors, AA, Givertz, MM, Mansoor, GA, Bloomfield, DM, Jia, G, DeLucca, P, Massie, B, Dittrich, H, and Cotter, G. "Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study." Eur Heart J 32, no. 12 (June 2011): 1519-1534. Full Text Link to Item
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  - Fiuzat, M, and O'Connor, CM. "Bucindolol: new hopes from reviewing past data." Drugs Today (Barc) 47, no. 5 (May 2011): 347-351. (Review) Full Text Link to Item
  - Voors, AA, Dittrich, HC, Massie, BM, DeLucca, P, Mansoor, GA, Metra, M, Cotter, G, Weatherley, BD, Ponikowski, P, Teerlink, JR, Cleland, JGF, O'Connor, CM, and Givertz, MM. "Effects of the adenosine A1 receptor antagonist rolofylline on renal function in patients with acute heart failure and renal dysfunction: results from PROTECT (Placebo-Controlled Randomized Study of the Selective Adenosine A1 Receptor Antagonist Rolofylline for Patients Hospitalized with Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function)." Journal of the American College of Cardiology 57, no. 19 (May 2011): 1899-1907. Full Text
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  - Velazquez, EJ, Lee, KL, Deja, MA, Jain, A, Sopko, G, Marchenko, A, Ali, IS, Pohost, G, Gradinac, S, Abraham, WT, Yii, M, Prabhakaran, D, Szwed, H, Ferrazzi, P, Petrie, MC, O'Connor, CM, Panchavinnin, P, She, L, Bonow, RO, Rankin, GR, Jones, RH, Rouleau, J-L, and STICH Investigators, . "Coronary-artery bypass surgery in patients with left ventricular dysfunction." The New England Journal of Medicine 364, no. 17 (April 4, 2011): 1607-1616. Full Text
  - Felker, GM, Lee, KL, Bull, DA, Redfield, MM, Stevenson, LW, Goldsmith, SR, LeWinter, MM, Deswal, A, Rouleau, JL, Ofili, EO, Anstrom, KJ, Hernandez, AF, McNulty, SE, Velazquez, EJ, Kfoury, AG, Chen, HH, Givertz, MM, Semigran, MJ, Bart, BA, Mascette, AM, Braunwald, E, O'Connor, CM, and NHLBI Heart Failure Clinical Research Network, . "Diuretic strategies in patients with acute decompensated heart failure." The New England Journal of Medicine 364, no. 9 (March 2011): 797-805. Full Text
  - Mahaffey, KW, Wampole, JL, Stebbins, A, Berdan, LG, McAfee, D, Rorick, TL, French, JK, Kleiman, NS, O'Connor, CM, Cohen, EA, Granger, CB, Armstrong, PW, and APEX-AMI Investigators, . "Strategic lessons from the clinical event classification process for the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial." Contemporary Clinical Trials 32, no. 2 (March 2011): 178-187. Full Text
  - Sherwood, A, O'Connor, CM, Routledge, FS, Hinderliter, AL, Watkins, LL, Babyak, MA, Koch, GG, Adams, KF, Dupree, CS, Chang, PP, Hoffman, BM, Johnson, J, Bowers, M, Johnson, KS, and Blumenthal, JA. "Coping effectively with heart failure (COPE-HF): design and rationale of a telephone-based coping skills intervention." Journal of Cardiac Failure 17, no. 3 (March 2011): 201-207. Full Text
  - Jiang, W, Krishnan, R, Kuchibhatla, M, Cuffe, MS, Martsberger, C, Arias, RM, O'Connor, CM, and SADHART-CHF Investigators, . "Characteristics of depression remission and its relation with cardiovascular outcome among patients with chronic heart failure (from the SADHART-CHF Study)." Am J Cardiol 107, no. 4 (February 15, 2011): 545-551. Full Text Link to Item
  - Gheorghiade, M, Pang, PS, O'Connor, CM, Prasad, K, McMurray, J, Teerlink, JR, Fiuzat, M, Sabbah, H, and Komajda, M. "Clinical development of pharmacologic agents for acute heart failure syndromes: a proposal for a mechanistic translational phase." American Heart Journal 161, no. 2 (February 2011): 224-232. Full Text
  - O'Connor, CM, Koch, WJ, and Mann, DL. "Highlights of the 2010 scientific sessions of the Heart Failure Society of America, San Diego, California, September 12-15, 2010." J Card Fail 17, no. 2 (February 2011): 92-99. Full Text Link to Item
  - Sherwood, A, Blumenthal, JA, Hinderliter, AL, Koch, GG, Adams, KF, Dupree, CS, Bensimhon, DR, Johnson, KS, Trivedi, R, Bowers, M, Christenson, RH, and O'Connor, CM. "Worsening depressive symptoms are associated with adverse clinical outcomes in patients with heart failure." J Am Coll Cardiol 57, no. 4 (January 25, 2011): 418-423. Full Text Link to Item
  - O'Connor, CM, Albert, NM, Curtis, AB, Gheorghiade, M, Heywood, JT, McBride, ML, Inge, PJ, Mehra, MR, Reynolds, D, Walsh, MN, Yancy, CW, and Fonarow, GC. "patient and practice factors associated with improvement in use of guideline-recommended therapies for outpatients with heart failure (from the IMPROVE HF trial)." Am J Cardiol 107, no. 2 (January 15, 2011): 250-258. Full Text Link to Item
  - Jones, WS, Patel, MR, Holleran, SA, Harrison, JK, O'Connor, CM, and III, HRP. "Trends in the use of diagnostic coronary angiography, percutaneous coronary intervention, and coronary artery bypass graft surgery across North Carolina." American Heart Journal 162, no. 5 (2011): 932-937. Full Text
  - Adams, KF, Mehra, MR, Oren, RM, O'Connor, CM, Chiong, JR, Ghali, JK, Lenihan, DJ, Dunlap, SH, Patterson, JH, Schwartz, TA, and Felker, GM. "Prospective evaluation of the association between cardiac troponin T and markers of disturbed erythropoiesis in patients with heart failure." Am Heart J 160, no. 6 (December 2010): 1142-1148. Full Text Link to Item
  - Echols, MR, and O'Connor, CM. "Depression after myocardial infarction." Curr Heart Fail Rep 7, no. 4 (December 2010): 185-193. (Review) Full Text Link to Item
  - Fiuzat, M, Shaw, LK, Thomas, L, Felker, GM, and O'Connor, CM. "United States stock market performance and acute myocardial infarction rates in 2008-2009 (from the Duke Databank for Cardiovascular Disease)." Am J Cardiol 106, no. 11 (December 1, 2010): 1545-1549. Full Text Link to Item
  - Walsh, MN, Yancy, CW, Albert, NM, Curtis, AB, Gheorghiade, M, Heywood, JT, Inge, PJ, McBride, ML, Mehra, MR, O'Connor, CM, Reynolds, D, and Fonarow, GC. "Equitable improvement for women and men in the use of guideline-recommended therapies for heart failure: findings from IMPROVE HF." J Card Fail 16, no. 12 (December 2010): 940-949. Full Text Link to Item
  - Ponikowski, P, Mitrovic, V, O'Connor, CM, Dittrich, H, Cotter, G, Massie, BM, Givertz, MM, Chen, E, Murray, M, Weatherley, BD, Fujita, KP, and Metra, M. "Haemodynamic effects of rolofylline in the treatment of patients with heart failure and impaired renal function." European Journal of Heart Failure 12, no. 11 (November 2010): 1238-1246. Full Text
  - Wu, AH, Ghali, JK, Neuberg, GW, O'Connor, CM, Carson, PE, and Levy, WC. "Uric acid level and allopurinol use as risk markers of mortality and morbidity in systolic heart failure." Am Heart J 160, no. 5 (November 2010): 928-933. Full Text Link to Item
  - Carson, P, Fiuzat, M, O'Connor, C, Anand, I, Plehn, J, Lindenfeld, JA, Silver, M, White, M, Miller, A, Davis, G, Robertson, AD, Bristow, M, and Gottlieb, S. "Determination of hospitalization type by investigator case report form or adjudication committee in a large heart failure clinical trial (β-Blocker Evaluation of Survival Trial [BEST])." Am Heart J 160, no. 4 (October 2010): 649-654. Full Text Link to Item
  - Massie, BM, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Cotter, G, Weatherley, BD, Cleland, JGF, Givertz, MM, Voors, A, DeLucca, P, Mansoor, GA, Salerno, CM, Bloomfield, DM, Dittrich, HC, and PROTECT Investigators and Committees, . "Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure." The New England Journal of Medicine 363, no. 15 (October 2010): 1419-1428. Full Text
  - Rouleau, JL, Michler, RE, Velazquez, EJ, Oh, JK, O'Connor, CM, Desvigne-Nickens, P, Sopko, G, Lee, KL, and Jones, RH. "The STICH trial: evidence-based conclusions." European Journal of Heart Failure 12, no. 10 (October 2010): 1028-1030. Full Text
  - Heywood, JT, Fonarow, GC, Yancy, CW, Albert, NM, Curtis, AB, Gheorghiade, M, Inge, PJ, McBride, ML, Mehra, MR, O'Connor, CM, Reynolds, D, and Walsh, MN. "Comparison of medical therapy dosing in outpatients cared for in cardiology practices with heart failure and reduced ejection fraction with and without device therapy: report from IMPROVE HF." Circ Heart Fail 3, no. 5 (September 2010): 596-605. Full Text Link to Item
  - Kociol, RD, Pang, PS, Gheorghiade, M, Fonarow, GC, O'Connor, CM, and Felker, GM. "Troponin elevation in heart failure prevalence, mechanisms, and clinical implications." Journal of the American College of Cardiology 56, no. 14 (September 2010): 1071-1078. (Review) Full Text
  - Watkins, LL, Blumenthal, JA, Babyak, MA, Davidson, JRT, McCants, CB, O'Connor, C, and Sketch, MH. "Phobic anxiety and increased risk of mortality in coronary heart disease." Psychosomatic Medicine 72, no. 7 (September 2010): 664-671. Full Text Open Access Copy
  - Fonarow, GC, Albert, NM, Curtis, AB, Stough, WG, Gheorghiade, M, Heywood, JT, McBride, ML, Inge, PJ, Mehra, MR, O'Connor, CM, Reynolds, D, Walsh, MN, and Yancy, CW. "Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF)." Circulation 122, no. 6 (August 2010): 585-596. Full Text
  - Jones, RH, White, H, Velazquez, EJ, Shaw, LK, Pietrobon, R, Panza, JA, Bonow, RO, Sopko, G, O'Connor, CM, and Rouleau, J-L. "STICH (Surgical Treatment for Ischemic Heart Failure) trial enrollment." Journal of the American College of Cardiology 56, no. 6 (August 2010): 490-498. Full Text
  - O'Connor, CM, Jiang, W, Kuchibhatla, M, Silva, SG, Cuffe, MS, Callwood, DD, Zakhary, B, Stough, WG, Arias, RM, Rivelli, SK, Krishnan, R, and SADHART-CHF Investigators, . "Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial." Journal of the American College of Cardiology 56, no. 9 (August 2010): 692-699. Full Text
  - Povsic, TJ, and O'Connor, CM. "Cell therapy for heart failure: the need for a new therapeutic strategy." Expert Rev Cardiovasc Ther 8, no. 8 (August 2010): 1107-1126. (Review) Full Text Link to Item
  - West, RL, Hernandez, AF, O'Connor, CM, Starling, RC, and Califf, RM. "A review of dyspnea in acute heart failure syndromes." American Heart Journal 160, no. 2 (August 2010): 209-214. (Review) Full Text
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  - Aguilar, D, Solomon, SD, Køber, L, Rouleau, J-L, Skali, H, McMurray, JJV, Francis, GS, Henis, M, O'Connor, CM, Diaz, R, Belenkov, YN, Varshavsky, S, Leimberger, JD, Velazquez, EJ, Califf, RM, and Pfeffer, MA. "Newly diagnosed and previously known diabetes mellitus and 1-year outcomes of acute myocardial infarction: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial." Circulation 110, no. 12 (September 13, 2004): 1572-1578. Full Text
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  - Gattis, WA, and O'Connor, CM. "Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure." The American Journal of Cardiology 93, no. 9A (May 2004): 74B-76B. Full Text
  - Serebruany, VL, Malinin, AI, Lowry, DR, Sane, DC, Webb, RL, Gottlieb, SO, O'Connor, CM, and Hennekens, CH. "Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits." J Cardiovasc Pharmacol 43, no. 5 (May 2004): 677-684. Link to Item
  - Gheorghiade, M, Gattis, WA, O'Connor, CM, Adams, KF, Elkayam, U, Barbagelata, A, Ghali, JK, Benza, RL, McGrew, FA, Klapholz, M, Ouyang, J, Orlandi, C, and Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Congestive Heart Failure (ACTIV in CHF) Investigators, . "Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial." Jama 291, no. 16 (April 2004): 1963-1971. Full Text
  - Klein, L, Gattis, WA, Borrello, F, Wu, E, O'Connor, CM, and Gheorghiade, M. "Effects of amino acid supplementation on left ventricular remodeling in patients with chronic heart failure with decreased systolic function and diabetes mellitus: rationale and design of a magnetic resonance imaging study." The American Journal of Cardiology 93, no. 8A (April 2004): 44A-46A. Full Text
  - Massie, BM, Krol, WF, Ammon, SE, Armstrong, PW, Cleland, JG, Collins, JF, Ezekowitz, M, Jafri, SM, O'Connor, CM, Packer, M, Schulman, KA, Teo, K, and Warren, S. "The Warfarin and Antiplatelet Therapy in Heart Failure trial (WATCH): rationale, design, and baseline patient characteristics." Journal of Cardiac Failure 10, no. 2 (April 2004): 101-112. Full Text
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  - Bourque, JM, Velazquez, EJ, Borges-Neto, S, Shaw, LK, Whellan, DJ, and O'connor, CM. "Clinical characteristics and referral pattern of patients with left ventricular dysfunction and significant coronary artery disease undergoing radionuclide imaging." J Nucl Cardiol 11, no. 2 (March 2004): 118-125. Full Text Link to Item
  - Hudson, MP, O'Connor, CM, Gattis, WA, Tasissa, G, Hasselblad, V, Holleman, CM, Gaulden, LH, Sedor, F, and Ohman, EM. "Implications of elevated cardiac troponin T in ambulatory patients with heart failure: a prospective analysis." Am Heart J 147, no. 3 (March 2004): 546-552. Full Text Link to Item
  - Butler, J, Forman, DE, Abraham, WT, Gottlieb, SS, Loh, E, Massie, BM, O'Connor, CM, Rich, MW, Stevenson, LW, Wang, Y, Young, JB, and Krumholz, HM. "Relationship between heart failure treatment and development of worsening renal function among hospitalized patients." Am Heart J 147, no. 2 (February 2004): 331-338. Full Text Link to Item
  - Whellan, DJ, O'Connor, CM, and Pina, I. "Training trials in heart failure: time to exercise restraint?." Am Heart J 147, no. 2 (February 2004): 190-192. Full Text Link to Item
  - Cabell, CH, Trichon, BH, Velazquez, EJ, Dumesnil, JG, Anstrom, KJ, Ryan, T, Miller, AB, Belkin, RN, Cropp, AB, O'Connor, CM, and Jollis, JG. "Importance of echocardiography in patients with severe nonischemic heart failure: the second Prospective Randomized Amlodipine Survival Evaluation (PRAISE-2) echocardiographic study." American Heart Journal 147, no. 1 (January 2004): 151-157. Full Text
  - Forman, DE, Butler, J, Wang, Y, Abraham, WT, O'Connor, CM, Gottlieb, SS, Loh, E, Massie, BM, Rich, MW, Stevenson, LW, Young, JB, and Krumholz, HM. "Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure." Journal of the American College of Cardiology 43, no. 1 (January 2004): 61-67. Full Text
  - Modest, GA, Kaufmann, J, Nieto, FJ, Dunne, MW, Benner, RJ, O'Connor, CM, Pfeffer, MA, Muhlestein, JB, Yao, L, Gupta, S, Fisher, MR, Cook, TD, Pislaru, S, and Werf, FVD. "Antibiotics and Coronary Heart Disease [3] (multiple letters)." Journal of the American Medical Association 291, no. 3 (2004): 302-303. Full Text
  - Swenson, JR, O'Connor, CM, Barton, D, Van Zyl, LT, Swedberg, K, Forman, LM, Gaffney, M, Glassman, AH, and Sertraline Antidepressant Heart Attack Randomized Trial (SADHART) Group, . "Influence of depression and effect of treatment with sertraline on quality of life after hospitalization for acute coronary syndrome." The American Journal of Cardiology 92, no. 11 (December 2003): 1271-1276. Full Text
  - Bourque, JM, Hasselblad, V, Velazquez, EJ, Borges-Neto, S, and O'connor, CM. "Revascularization in patients with coronary artery disease, left ventricular dysfunction, and viability: a meta-analysis." Am Heart J 146, no. 4 (October 2003): 621-627. Full Text Link to Item
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  - Felker, GM, Gattis, WA, Leimberger, JD, Adams, KF, Cuffe, MS, Gheorghiade, M, and O'Connor, CM. "Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure." The American Journal of Cardiology 92, no. 5 (September 2003): 625-628. Full Text
  - O'Connor, CM, Dunne, MW, Pfeffer, MA, Muhlestein, JB, Yao, L, Gupta, S, Benner, RJ, Fisher, MR, Cook, TD, and Investigators in the WIZARD Study, . "Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial." Jama 290, no. 11 (September 2003): 1459-1466. Full Text
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  - Trichon, BH, Glower, DD, Shaw, LK, Cabell, CH, Anstrom, KJ, Felker, GM, and O'Connor, CM. "Survival after coronary revascularization, with and without mitral valve surgery, in patients with ischemic mitral regurgitation." Circulation 108 Suppl 1 (September 2003): II103-II110. Full Text
  - Hernandez, AF, and O'Connor, CM. "Sparing a little may save a lot: lessons from the Studies of Left Ventricular Dysfunction (SOLVD)." J Am Coll Cardiol 42, no. 4 (August 20, 2003): 709-711. Link to Item
  - Serebruany, VL, Glassman, AH, Malinin, AI, Nemeroff, CB, Musselman, DL, van Zyl, LT, Finkel, MS, Krishnan, KRR, Gaffney, M, Harrison, W, Califf, RM, O'Connor, CM, and Sertraline AntiDepressant Heart Attack Randomized Trial Study Group, . "Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy." Circulation 108, no. 8 (August 11, 2003): 939-944. Full Text
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  - Serebruany, VL, Glassman, AH, Malinin, AI, Atar, D, Sane, DC, Oshrine, BR, Ferguson, JJ, and O'Connor, CM. "Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin." European Journal of Heart Failure 5, no. 4 (August 2003): 517-521. Full Text
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  - Lee, CR, Watkins, ML, Patterson, JH, Gattis, W, O'connor, CM, Gheorghiade, M, and Adams, KF. "Vasopressin: a new target for the treatment of heart failure." American Heart Journal 146, no. 1 (July 2003): 9-18. (Review) Full Text
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  - Klein, L, O'Connor, CM, Gattis, WA, Zampino, M, De Luca, L, Vitarelli, A, Fedele, F, and Gheorghiade, M. "Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: Review of trials and practical considerations." American Journal of Cardiology 91, no. 9 SUPPL. 1 (May 8, 2003): 18-40. Full Text
  - Klein, L, O'Connor, CM, Gattis, WA, Zampino, M, de Luca, L, Vitarelli, A, Fedele, F, and Gheorghiade, M. "Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations." Am J Cardiol 91, no. 9A (May 8, 2003): 18F-40F. (Review) Link to Item
  - Bourque, JM, Velazquez, EJ, Borges-Neto, S, Shaw, LK, Whellan, DJ, and O'Connor, CM. "Radionuclide viability testing: should it affect treatment strategy in patients with cardiomyopathy and significant coronary artery disease?." Am Heart J 145, no. 5 (May 2003): 758-767. (Review) Full Text Link to Item
  - O'Connor, CM, Gattis, WA, Adams, KF, Hasselblad, V, Chandler, B, Frey, A, Kobrin, I, Rainisio, M, Shah, MR, Teerlink, J, Gheorghiade, M, and Randomized Intravenous TeZosentan Study-4 Investigators, . "Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4)." Journal of the American College of Cardiology 41, no. 9 (May 2003): 1452-1457. Full Text
  - Felker, GM, Benza, RL, Chandler, AB, Leimberger, JD, Cuffe, MS, Califf, RM, Gheorghiade, M, O'Connor, CM, and OPTIME-CHF Investigators, . "Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study." Journal of the American College of Cardiology 41, no. 6 (March 2003): 997-1003. Full Text
  - Malinin, AI, O'Connor, CM, Dzhanashvili, AI, Sane, DC, and Serebruany, VL. "Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel?." American Heart Journal 145, no. 3 (March 2003): 397-403. (Review) Full Text
  - Trichon, BH, Felker, GM, Shaw, LK, Cabell, CH, and O'Connor, CM. "Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure." The American Journal of Cardiology 91, no. 5 (March 2003): 538-543. Full Text
  - Felker, GM, Adams, KF, Konstam, MA, O'Connor, CM, and Gheorghiade, M. "The problem of decompensated heart failure: nomenclature, classification, and risk stratification." Am Heart J 145, no. 2 Suppl (February 2003): S18-S25. (Review) Full Text Link to Item
  - Felker, GM, and O'connor, CM. "A bridge for the 21st century in heart transplantation?." Am Heart J 145, no. 2 (February 2003): 198-199. Full Text Link to Item
  - Gheorghiade, M, Adams, KF, Gattis, WA, Teerlink, JR, Orlandi, C, and O'Connor, CM. "Surrogate end points in heart failure trials." Am Heart J 145, no. 2 Suppl (February 2003): S67-S70. Full Text Link to Item
  - Gheorghiade, M, Gattis, WA, Adams, KF, Jaffe, AS, O'Connor, CM, Pilot Randomized Study of Nesiritide versus Dobutamine in Heart Failure, , and Duke University Cooperative Cardiovascular Studies Investigators, . "Rationale and design of the pilot randomized study of nesiritide versus dobutamine in heart failure (PRESERVD-HF)." Am Heart J 145, no. 2 Suppl (February 2003): S55-S57. Full Text Link to Item
  - Gheorghiade, M, Gattis, WA, Barbagelata, A, Adams, KF, Elkayam, U, Orlandi, C, O'Connor, CM, and Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Congestive Heart Failure Investigators, . "Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure." American Heart Journal 145, no. 2 Suppl (February 2003): S51-S54. Full Text
  - Gheorghiade, M, Gattis, WA, Lukas, MA, O'Connor, CM, and Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure Investigators, . "Rationale and design of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) study." American Heart Journal 145, no. 2 Suppl (February 2003): S60-S61. Full Text
  - Gheorghiade, M, Gattis, WA, O'Connor, CM, and Adams, KF. "Introduction." American Heart Journal 145, no. 2 (February 2003): S1-S2. Full Text
  - O'Connor, CM, Gattis, WA, Adams, KF, Shah, MR, Frey, A, Gheorghiade, M, and Randomized Intravenous Tezosentan Study Investigators, . "Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the fourth Randomized Intravenous Tezosentan Study (RITZ-4)." Am Heart J 145, no. 2 Suppl (February 2003): S58-S59. Full Text Link to Item
  - O'Connor, CM, Gattis, WA, Teerlink, JR, Adams, KF, and Gheorghiade, M. "Design considerations and proposed template for clinical trials in hospitalized patients with decompensated chronic heart failure." Am Heart J 145, no. 2 Suppl (February 2003): S47-S50. Full Text Link to Item
  - Zampino, M, O'Connor, CM, Gattis, WA, Adams, KF, and Gheorghiade, M. "Concomitant use of a positive inotropic agent to create a bridge to the successful initiation of beta-blocker therapy in patients with heart failure: a proposal for a trial." Am Heart J 145, no. 2 Suppl (February 2003): S62-S66. Full Text Link to Item
  - Gattis, WA, O'Connor, CM, Leimberger, JD, Felker, GM, Adams, KF, and Gheorghiade, M. "Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure." The American Journal of Cardiology 91, no. 2 (January 2003): 169-174. Full Text
  - Hasdai, D, Topol, EJ, Kilaru, R, Battler, A, Harrington, RA, Vahanian, A, Ohman, EM, Granger, CB, Van de Werf, F, Simoons, ML, O'connor, CM, and Holmes, DR. "Frequency, patient characteristics, and outcomes of mild-to-moderate heart failure complicating ST-segment elevation acute myocardial infarction: lessons from 4 international fibrinolytic therapy trials." American Heart Journal 145, no. 1 (January 2003): 73-79. Full Text
  - Serebruany, VL, Glassman, AH, Malinin, AI, Sane, DC, Finkel, MS, Krishnan, RR, Atar, D, Lekht, V, and O'Connor, CM. "Enhanced platelet/endothelial activation in depressed patients with acute coronary syndromes: Evidence from recent clinical trials." Blood Coagulation and Fibrinolysis 14, no. 6 (2003): 563-567. Full Text
  - Bourque, JMD, Velazquez, EJ, Borges-Neto, S, Hasselblad, V, and O'Connor, CM. "A reappraisal of myocardial viability testing in patients with coronary artery disease and left ventricular dysfunction: Can meta-analysis be trusted?." Heartdrug 2, no. 4 (December 1, 2002): 204-205. (Letter) Full Text
  - Gheorghiade, M, Gattis, WA, Lukas, MA, and O'Connor, CM. "Rationale and design of the initiation management predischarge: Process for assessment of carvedilol therapy for heart failure (IMPACT-HF) study." Heartdrug 2, no. 4 (December 1, 2002): 164-166. Full Text
  - Serebruany, VL, McKenzie, ME, Meister, AF, Fuzaylov, SY, Gurbel, PA, Atar, D, Gattis, WA, and O'Connor, CM. "Failure of platelet parameters and biomarkers to correlate platelet function to severity and etiology of heart failure in patients enrolled in the EPCOT trial: With special reference to the hemodyne® hemostatic analyzer." Pathophysiology of Haemostasis and Thrombosis 32, no. 1 (December 1, 2002): 8-15. Full Text
  - O'Connor, CM, Gattis, WA, Adams, KF, Shah, MR, Kobrin, I, Frey, A, and Gheorghiade, M. "Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the Randomized Intravenous Tezosentan study (RITZ-4)." Am Heart J 144, no. 4 (October 2002): 583-588. Link to Item
  - Carney, RM, Blumenthal, JA, Stein, PK, Watkins, L, Catellier, D, Berkman, LF, Czajkowski, SM, O'Connor, C, Stone, PH, and Freedland, KE. "Depression, heart rate variability, and acute myocardial infarction." Revista De Psiquiatria Clinica 29, no. 3 (September 14, 2002): 158-159.
  - Trichon, BH, and O'Connor, CM. "Secondary mitral and tricuspid regurgitation accompanying left ventricular systolic dysfunction: is it important, and how is it treated?." Am Heart J 144, no. 3 (September 2002): 373-376. (Review) Link to Item
  - Glassman, AH, O'Connor, CM, Califf, RM, Swedberg, K, Schwartz, P, Bigger, JT, Krishnan, KRR, van Zyl, LT, Swenson, JR, Finkel, MS, Landau, C, Shapiro, PA, Pepine, CJ, Mardekian, J, Harrison, WM, Barton, D, Mclvor, M, and Sertraline Antidepressant Heart Attack Randomized Trial (SADHEART) Group, . "Sertraline treatment of major depression in patients with acute MI or unstable angina." Jama 288, no. 6 (August 2002): 701-709. Full Text
  - Gurbel, PA, Malinin, AI, Callahan, KP, Serebruany, VL, and O'Connor, CM. "Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation." The American Journal of Cardiology 90, no. 3 (August 2002): 312-315. Full Text
  - Neuberg, GW, Miller, AB, O'Connor, CM, Belkin, RN, Carson, PE, Cropp, AB, Frid, DJ, Nye, RG, Pressler, ML, Wertheimer, JH, Packer, M, and PRAISE Investigators. Prospective Randomized Amlodipine Survival Evaluation, . "Diuretic resistance predicts mortality in patients with advanced heart failure." American Heart Journal 144, no. 1 (July 2002): 31-38. Full Text
  - O'Connor, CM, Velazquez, EJ, Gardner, LH, Smith, PK, Newman, MF, Landolfo, KP, Lee, KL, Califf, RM, and Jones, RH. "Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank)." The American Journal of Cardiology 90, no. 2 (July 2002): 101-107. Full Text
  - Whellan, DJ, and O'Connor, CM. "The state of exercise training: a need for action." Am Heart J 144, no. 1 (July 2002): 1-4. Link to Item
  - Gottlieb, SS, Abraham, W, Butler, J, Forman, DE, Loh, E, Massie, BM, O'connor, CM, Rich, MW, Stevenson, LW, Young, J, and Krumholz, HM. "The prognostic importance of different definitions of worsening renal function in congestive heart failure." Journal of Cardiac Failure 8, no. 3 (June 2002): 136-141. Full Text
  - Gurbel, PA, Gattis, WA, Fuzaylov, SF, Gaulden, L, Hasselblad, V, Serebruany, VL, and O'Connor, CM. "Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?." American heart journal 143, no. 6 (June 2002): 1068-1075. (Academic Article)
  - Shah, MR, Hasselblad, V, Stinnett, SS, Kramer, JM, Grossman, S, Gheorghiade, M, Adams, KF, Swedberg, K, Califf, RM, and O'Connor, CM. "Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure." European Journal of Heart Failure 4, no. 3 (June 2002): 297-304. Full Text
  - Cuffe, MS, Califf, RM, Adams, KF, Benza, R, Bourge, R, Colucci, WS, Massie, BM, O'Connor, CM, Pina, I, Quigg, R, Silver, MA, Gheorghiade, M, and Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) Investigators, . "Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial." Jama 287, no. 12 (March 2002): 1541-1547. Full Text
  - Jiang, W, Hasselblad, V, Krishnan, RR, and O'Connor, CM. "Patients with CHF and depression have greater risk of mortality and morbidity than patients without depression." Journal of the American College of Cardiology 39, no. 5 (March 2002): 919-921. (Letter) Full Text
  - Blumenthal, JA, Babyak, M, Wei, J, O'Connor, C, Waugh, R, Eisenstein, E, Mark, D, Sherwood, A, Woodley, PS, Irwin, RJ, and Reed, G. "Usefulness of psychosocial treatment of mental stress-induced myocardial ischemia in men." The American Journal of Cardiology 89, no. 2 (January 2002): 164-168. Full Text
  - Cuffe, M, Califf, R, Adams, K, Benza, R, Bourge, R, Colucci, W, Massie, B, O'Connor, C, Pina, I, Quigg, R, Silver, M, Gheorghiade, M, and Hennersdorf, MG. "Intravenous milrinone is no better than standard therapy for people admitted with acute exacerbation of chronic heart failure." Evidence Based Cardiovascular Medicine 6, no. 4 (January 1, 2002): 154-155. Full Text
  - Felker, GM, Shaw, LK, and O'Connor, CM. "A standardized definition of ischemic cardiomyopathy for use in clinical research." Journal of the American College of Cardiology 39, no. 2 (January 2002): 210-218. Full Text
  - Gattis, WA, O'Connor, CM, and Gheorghiade, M. "The Initiation Management Predischarge Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) Study: design and implications." Reviews in Cardiovascular Medicine 3 Suppl 3 (January 2002): S48-S54.
  - Gheorghiade, M, Gattis, WA, and O'Connor, CM. "Treatment gaps in the pharmacologic management of heart failure." Rev Cardiovasc Med 3 Suppl 3 (2002): S11-S19. (Review) Link to Item
  - Jiang, W, Krishnan, RRK, and O'Connor, CM. "Depression and heart disease: evidence of a link, and its therapeutic implications." CNS Drugs 16, no. 2 (2002): 111-127. (Review) Link to Item
  - Lespérance, F, Frasure-Smith, N, Steinberg, DI, Glassman, AH, and O'Connor, CM. "Sertraline for treatment of depression in acute coronary syndromes [1] (multiple letters)." Journal of the American Medical Association 288, no. 19 (2002): 2403-2404. Full Text
  - Rozzini, R, Sabatini, T, Frisoni, GB, Trabucchi, M, Jiang, W, Krishnan, RR, and O'Connor, CM. "Depression and major outcomes in older patients with heart failure [4] (multiple letters)." Archives of Internal Medicine 162, no. 3 (2002): 362-364.
  - Serebruany, VL, McKenzie, ME, Meister, AF, Fuzaylov, SY, Gurbel, PA, Atar, D, Gattis, WA, and O'Connor, CM. "Failure of platelet parameters and biomarkers to correlate platelet function to severity and etiology of heart failure in patients enrolled in the EPCOT trial. With special reference to the Hemodyne hemostatic analyzer. Whole Blood Impedance Aggregometry for the Assessment of Platelet Function in Patients with Congestive Heart Failure." Pathophysiol Haemost Thromb 32, no. 1 (January 2002): 8-15. Full Text Link to Item
  - Serebruanya, VL, McKenzie, ME, Meistera, AF, Fuzaylov, SY, Gurbel, PA, Atar, D, Gattis, WA, and O'Connor, CM. "Whole blood impedance aggregometry for the assessment of platelet function in patients with congestive heart failure (EPCOT trial)." European Journal of Heart Failure 4, no. 4 (2002): 461-467. Full Text
  - Shah, BR, Velazquez, E, Shaw, LK, Bart, B, O'Connor, C, and Wagner, GS. "Revascularization improves survival in ischemic cardiomyopathy regardless of electrocardiographic criteria for prior small-to-medium myocardial infarcts." Am Heart J 143, no. 1 (January 2002): 111-117. Link to Item
  - Felker, GM, and O'connor, CM. "Between Scylla and Charybdis: The choice of inotropic agent for decompensated heart failure." Am Heart J 142, no. 6 (December 2001): 932-933. Full Text Link to Item
  - Serebruany, VL, Davis, CJ, Meister, AF, Atar, D, Whellan, DJ, and O'Connor, CM. "Biomarkers and exercise training: A possible missing link between physical activity and mortality benefit in patients with heart failure." Heartdrug 1, no. 2 (December 1, 2001): 110-124. (Review) Full Text
  - Shah, MR, Hasselblad, V, Gheorghiade, M, Adams, KF, Swedberg, K, Califf, RM, and O'Connor, CM. "Prognostic usefulness of the six-minute walk in patients with advanced congestive heart failure secondary to ischemic or nonischemic cardiomyopathy." The American Journal of Cardiology 88, no. 9 (November 2001): 987-993. Full Text
  - Whellan, DJ, Gaulden, L, Gattis, WA, Granger, B, Russell, SD, Blazing, MA, Cuffe, MS, and O'Connor, CM. "The benefit of implementing a heart failure disease management program." Arch Intern Med 161, no. 18 (October 8, 2001): 2223-2228. Link to Item
  - Carney, RM, Blumenthal, JA, Stein, PK, Watkins, L, Catellier, D, Berkman, LF, Czajkowski, SM, O'Connor, C, Stone, PH, and Freedland, KE. "Depression, heart rate variability, and acute myocardial infarction." Circulation 104, no. 17 (October 2001): 2024-2028. Full Text
  - ENRICHD Investigators, . "Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design." Psychosomatic Medicine 63, no. 5 (September 2001): 747-755.
  - Felker, GM, and O'Connor, CM. "Inotropic therapy for heart failure: an evidence-based approach." Am Heart J 142, no. 3 (September 2001): 393-401. (Review) Full Text Link to Item
  - O'Connor, CM, Gattis, WA, Hellkamp, AS, Langer, A, Larsen, RL, Harrington, RA, Berkowitz, SD, O'Gara, PT, Kopecky, SL, Gheorghiade, M, Daly, R, Califf, RM, and Fuster, V. "Comparison of two aspirin doses on ischemic stroke in post-myocardial infarction patients in the warfarin (Coumadin) Aspirin Reinfarction Study (CARS)." The American Journal of Cardiology 88, no. 5 (September 2001): 541-546. Full Text
  - ENRICHD Investigators, . "Enhancing recovery in coronary heart disease (ENRICHD): baseline characteristics." The American Journal of Cardiology 88, no. 3 (August 2001): 316-322. Full Text
  - Jiang, W, Alexander, J, Christopher, E, Kuchibhatla, M, Gaulden, LH, Cuffe, MS, Blazing, MA, Davenport, C, Califf, RM, Krishnan, RR, and O'Connor, CM. "Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure." Archives of Internal Medicine 161, no. 15 (August 2001): 1849-1856. Full Text
  - Alexander, KP, Newby, LK, Hellkamp, AS, Harrington, RA, Peterson, ED, Kopecky, S, Langer, A, O'Gara, P, O'Connor, CM, Daly, RN, Califf, RM, Khan, S, and Fuster, V. "Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up." Journal of the American College of Cardiology 38, no. 1 (July 2001): 1-7. Full Text
  - Whellan, DJ, Shaw, LK, Bart, BA, Kraus, WE, Califf, RM, and O'Connor, CM. "Cardiac rehabilitation and survival in patients with left ventricular systolic dysfunction." American Heart Journal 142, no. 1 (July 2001): 160-166. Full Text
  - Rosenberg, EL, Ekman, P, Jiang, W, Babyak, M, Coleman, RE, Hanson, M, O'Connor, C, Waugh, R, and Blumenthal, JA. "Linkages between facial expressions of anger and transient myocardial ischemia in men with coronary artery disease." Emotion (Washington, D.C.) 1, no. 2 (June 2001): 107-115. Full Text
  - Serebruany, VL, O'Connor, CM, and Gurbel, PA. "Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease." The American journal of cardiology 87, no. 12 (June 2001): 1398-1400. (Academic Article)
  - Shah, MR, Hasselblad, V, Stinnett, SS, Gheorghiade, M, Swedberg, K, Califf, RM, and O'Connor, CM. "Hemodynamic profiles of advanced heart failure: association with clinical characteristics and long-term outcomes." Journal of Cardiac Failure 7, no. 2 (June 2001): 105-113. Full Text
  - Shah, MR, Stinnett, SS, McNulty, SE, Gheorghiade, M, Zannad, F, Uretsky, B, Adams, KF, Califf, RM, and O'connor, CM. "Hemodynamics as surrogate end points for survival in advanced heart failure: an analysis from FIRST." American Heart Journal 141, no. 6 (June 2001): 908-914. Full Text
  - Serebruany, VL, Gurbel, PA, and O'Connor, CM. "Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors." Pharmacological Research 43, no. 5 (May 2001): 453-462. Full Text
  - Shah, MR, O'Connor, CM, Sopko, G, Hasselblad, V, Califf, RM, and Stevenson, LW. "Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE): design and rationale." American Heart Journal 141, no. 4 (April 2001): 528-535. Full Text
  - Gattis, WA, and O'Connor, CM. "Effect of amlodipine on mode of death in advanced heart failure." Cardiology Review 18, no. 2 (March 12, 2001): 13-19. (Review)
  - Felker, GM, and O'Connor, CM. "Rational use of inotropic therapy in heart failure." Curr Cardiol Rep 3, no. 2 (March 2001): 108-113. (Review) Link to Item
  - Gattis, WA, Galanos, A, and O'Connor, CM. "Angiotensin-converting enzyme inhibitor dosing in heart failure: what is optimal?." Am Heart J 141, no. 3 (March 2001): 331-333. Full Text Link to Item
  - Gurbel, PA, O'Connor, CM, Dalesandro, MR, and Serebruany, VL. "Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy." The American journal of cardiology 87, no. 6 (March 2001): 774-7, A7. (Academic Article)
  - Serebruany, VL, Alford, AB, Meister, AF, Fuzaylov, SY, Gattis, WA, Gurbel, PA, and O'Connor, CM. "Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial)." Thrombosis research 101, no. 6 (March 2001): 427-433. (Academic Article)
  - Shah, MR, and O'connor, CM. "The congestion score: a simple tool for a complicated disease?." Am Heart J 140, no. 6 (December 2000): 824-826. Full Text Link to Item
  - Nemeroff, CB, and O'connor, CM. "Introduction." Am Heart J 140, no. 4 Suppl (October 2000): 55-56. Link to Item
  - Nemeroff, CB, and O’Connor, CM. "Introduction." American Heart Journal 140, no. 4 (October 2000): S55-S56. Full Text
  - O'Connor, CM, Gattis, WA, Shaw, L, Cuffe, MS, and Califf, RM. "Clinical characteristics and long-term outcomes of patients with heart failure and preserved systolic function." The American Journal of Cardiology 86, no. 8 (October 2000): 863-867. Full Text
  - O'connor, CM, Gurbel, PA, and Serebruany, VL. "Depression and ischemic heart disease." Am Heart J 140, no. 4 Suppl (October 2000): 63-69. (Review) Link to Item
  - Gattis, W, and O'Connor, CM. "Calcium antagonist use in heart failure: A re-evalutaion of treatment options." Drugs 59, no. SPEC. ISS. 2 (September 14, 2000): 17-24. (Review)
  - Varia, I, Logue, E, O'connor, C, Newby, K, Wagner, HR, Davenport, C, Rathey, K, and Krishnan, KR. "Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin." Am Heart J 140, no. 3 (September 2000): 367-372. Full Text Link to Item
  - Carson, PA, O'Connor, CM, Miller, AB, Anderson, S, Belkin, R, Neuberg, GW, Wertheimer, JH, Frid, D, Cropp, A, and Packer, M. "Circadian rhythm and sudden death in heart failure." Journal of the American College of Cardiology 36, no. 2 (August 29, 2000): 541-546. Full Text
  - Carson, PA, O'Connor, CM, Miller, AB, Anderson, S, Belkin, R, Neuberg, GW, Wertheimer, JH, Frid, D, Cropp, A, and Packer, M. "Circadian rhythm and sudden death in heart failure: results from Prospective Randomized Amlodipine Survival Trial." J Am Coll Cardiol 36, no. 2 (August 2000): 541-546. Link to Item
  - Davis, CJ, Gurbel, PA, Gattis, WA, Fuzaylov, SY, Nair, GV, O'Connor, CM, and Serebruany, VL. "Hemostatic abnormalities in patients with congestive heart failure: diagnostic significance and clinical challenge." International journal of cardiology 75, no. 1 (August 2000): 15-21. (Academic Article)
  - Kong, DF, Blazing, MA, and O'Connor, CM. "Advances in the approach to acute coronary syndromes." Hosp Pract (1995) 35, no. 4 (April 15, 2000): 61-64. (Review) Link to Item
  - O'Connor, CM, Gattis, WA, and Ryan, TJ. "The role of clinical nonfatal end points in cardiovascular phase II/III clinical trials." Am Heart J 139, no. 4 (April 2000): S143-S154. Link to Item
  - Serebruany, VL, Lowry, DR, Fuzailov, SY, Levine, DJ, O'Connor, CM, and Gurbel, PA. "Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction." Journal of thrombosis and thrombolysis 9, no. 3 (April 2000): 229-234. (Academic Article)
  - Califf, RM, and O'Connor, CM. "Beta-blocker therapy for heart failure: the evidence is in, now the work begins." Jama 283, no. 10 (March 2000): 1335-1337. Full Text
  - Shah, A, Wagner, GS, Granger, CB, O'Connor, CM, Green, CL, Trollinger, KM, Califf, RM, and Krucoff, MW. "Prognostic implications of TIMI flow grade in the infarct related artery compared with continuous 12-lead ST-segment resolution analysis. Reexamining the "gold standard" for myocardial reperfusion assessment." Journal of the American College of Cardiology 35, no. 3 (March 2000): 666-672. Full Text
  - Gurbel, PA, Kereiakes, DJ, Dalesandro, MR, Bahr, RD, O'Connor, CM, and Serebruany, VL. "Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department." American heart journal 139, no. 2 Pt 1 (February 2000): 320-328. (Academic Article)
  - Bosworth, HB, Steffens, DC, Kuchibhatla, MN, Jiang, WJ, Arias, RM, O'Connor, CM, and Krishnan, KRR. "The relationship of social support, social networks and negative events with depression in patients with coronary artery disease." Aging and Mental Health 4, no. 3 (January 1, 2000): 253-258. Full Text
  - Califf, RM, and O'Connor, CM. "β-Blocker therapy for heart failure: The evidence is in, now the work begins." Journal of the American Medical Association 283, no. 10 (January 1, 2000): 1335-1337. Full Text
  - Cuffe, MS, Califf, RM, Adams, KF, Bourge, RC, Colucci, W, Massie, B, O'Connor, CM, Pina, I, Quigg, R, Silver, M, Robinson, LA, Leimberger, JD, and Gheorghiade, M. "Rationale and design of the OPTIME CHF trial: outcomes of a prospective trial of intravenous milrinone for exacerbations of chronic heart failure." American Heart Journal 139, no. 1 Pt 1 (January 2000): 15-22. Full Text
  - Cuffe, MS, Califf, RM, Adams, KF, Bourge, RC, Colucci, W, Massie, B, O'Connor, CM, Pina, I, Quigg, R, Silver, M, Robinson, LA, Leimberger, JD, and Gheorghiade, M. "Rationale and design of the OPTIME CHF trial: Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure." American Heart Journal 139, no. 1 I (January 1, 2000): 15-22. Full Text
  - Gattis, W, and O'Connor, CM. "[Calcium antagonists in the treatment of heart failure. Re-evaluation of therapeutic strategies]." Drugs 59 Spec No 2 (2000): 17-24. (Review) Link to Item
  - Gurbel, PA, Kereiakes, DJ, Dalesandro, MR, Bahr, RD, O'Connor, CM, and Serebruany, VL. "Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department." American Heart Journal 139, no. 2 I (2000): 320-328.
  - O'Connor, CM, Gurbel, PA, and Serebruany, VL. "Depression and ischemic heart disease." American Heart Journal 140, no. 4 SUPPL. (January 1, 2000). Full Text
  - Fortner, MR, Brown, K, Varia, IM, Gersing, KR, O'Connor, C, and Doraiswamy, PM. "Effect of Bupropion SR on the Quality of Life of Elderly Depressed Patients With Comorbid Medical Disorders." Primary Care Companion to the Journal of Clinical Psychiatry 1, no. 6 (December 1999): 174-179. Full Text
  - O'Connor, CM, Gattis, WA, Gheorghiade, M, Granger, CB, Gilbert, J, McKenney, JM, Messineo, FC, Burnett, JC, Katz, SD, Elkayam, U, Kasper, EK, Goldstein, S, Cody, RJ, and Massie, BM. "A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: the U.S. ecadotril pilot safety study." Am Heart J 138, no. 6 Pt 1 (December 1999): 1140-1148. Link to Item
  - Velazquez, EJ, and O'Connor, CM. "Heart failure after myocardial infarction: A good heart is hard to find." American heart journal 138, no. 6 Pt 1 (December 1999): 1009-1011. Full Text
  - Orloff, DG, Blazing, MA, and O'Connor, CM. "Atherosclerotic disease in non-insulin-dependent diabetes mellitus: role of abnormal lipids and the place for lipid-altering therapies." Am Heart J 138, no. 5 Pt 1 (November 1999): S406-S412. (Review) Link to Item
  - Del Carlo, CH, and O'Connor, CM. "Cardiac troponins in congestive heart failure." Am Heart J 138, no. 4 Pt 1 (October 1999): 646-653. (Review) Link to Item
  - Doraiswamy, PM, MacFall, J, Krishnan, KR, O'Connor, C, Wan, X, Benaur, M, Lewandowski, M, and Fortner, M. "Magnetic resonance assessment of cerebral perfusion in depressed cardiac patients: preliminary findings." Am J Psychiatry 156, no. 10 (October 1999): 1641-1643. Full Text Link to Item
  - Langer, A, Fisher, M, Califf, RM, Goodman, S, O'Connor, CM, Harrington, RA, and Fuster, V. "Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada. The CARS Investigators (Coumadin/Aspirin Reinfarction Study)." The Canadian Journal of Cardiology 15, no. 10 (October 1999): 1095-1102.
  - Langer, A, Fisher, M, Califf, RM, Goodman, S, O'Connor, CM, Harrington, RA, and Fuster, V. "Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada." Canadian Journal of Cardiology 15, no. 10 (October 1, 1999): 1095-1102.
  - Gattis, WA, Hasselblad, V, Whellan, DJ, and O'Connor, CM. "Reduction in heart failure events by the addition of a clinical pharmacist to the heart failure management team: results of the Pharmacist in Heart Failure Assessment Recommendation and Monitoring (PHARM) Study." Archives of Internal Medicine 159, no. 16 (September 1999): 1939-1945. Full Text
  - Gurbel, PA, O'Connor, CM, Cummings, CC, and Serebruany, VL. "Clopidogrel: the future choice for preventing platelet activation during coronary stenting?." Pharmacological Research 40, no. 2 (August 1999): 107-111. (Review) Full Text
  - Nair, GV, Gurbel, PA, O'Connor, CM, Gattis, WA, Murugesan, SR, and Serebruany, VL. "Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors." The American journal of cardiology 84, no. 3 (August 1999): 321-3, A8. (Academic Article)
  - Serebruany, VL, Murugesan, SR, Pothula, A, Atar, D, Lowry, DR, O'Connor, CM, and Gurbel, PA. "Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy." European Journal of Heart Failure 1, no. 3 (August 1999): 243-249. Full Text
  - Blazing, MA, and O'Connor, CM. "Evidence supporting secondary prevention strategies." Curr Opin Cardiol 14, no. 4 (July 1999): 303-309. (Review) Link to Item
  - O'Connor, CM, Gattis, WA, Uretsky, BF, Adams, KF, McNulty, SE, Grossman, SH, McKenna, WJ, Zannad, F, Swedberg, K, Gheorghiade, M, and Califf, RM. "Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST)." American Heart Journal 138, no. 1 Pt 1 (July 1999): 78-86. Full Text
  - O'Connor, CM, Gattis, WA, and Swedberg, K. "Current and novel pharmacologic approaches in advanced heart failure." Heart Lung 28, no. 4 (July 1999): 227-242. (Review) Link to Item
  - O'Connor, CM, Radensky, PW, Unger, AN, and Martin, BC. "Hospital use and costs among patients with nonischemic cardiomyopathy in the first prospective randomized amlodipine survival evaluation study." Clin Ther 21, no. 7 (July 1999): 1254-1265. Full Text Link to Item
  - Shapiro, PA, Lespérance, F, Frasure-Smith, N, O'Connor, CM, Baker, B, Jiang, JW, Dorian, P, Harrison, W, and Glassman, AH. "An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT Trial). Sertraline Anti-Depressant Heart Attack Trial." Am Heart J 137, no. 6 (June 1999): 1100-1106. Link to Item
  - Kong, DF, Blazing, MA, and O'Connor, CM. "The health care burden of unstable angina." Cardiol Clin 17, no. 2 (May 1999): 247-261. (Review) Link to Item
  - O'Connor, CM, Gurbel, PA, and Serebruany, VL. "Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure." The American journal of cardiology 83, no. 9 (May 1999): 1345-1349. (Academic Article)
  - Adams, KF, Sueta, CA, Gheorghiade, M, O'Connor, CM, Schwartz, TA, Koch, GG, Uretsky, B, Swedberg, K, McKenna, W, Soler-Soler, J, and Califf, RM. "Gender differences in survival in advanced heart failure. Insights from the FIRST study." Circulation 99, no. 14 (April 1999): 1816-1821. Full Text
  - Whellan, DJ, Gattis, WA, Gaulden, L, Granger, B, and O'Connor, CM. "Disease management of congestive heart failure." Am J Manag Care 5, no. 4 (April 1999): 499-507. Link to Item
  - O'Connor, CM, Gattis, WA, Zannad, F, McNulty, SE, Gheorghiade, M, Adams, KF, Califf, RM, McKenna, WJ, Soler-Soler, J, and Swedberg, K. "Beta-blocker therapy in advanced heart failure: clinical characteristics and long-term outcomes." European Journal of Heart Failure 1, no. 1 (March 1999): 81-88. Full Text
  - Steffens, DC, O'Connor, CM, Jiang, WJ, Pieper, CF, Kuchibhatla, MN, Arias, RM, Look, A, Davenport, C, Gonzalez, MB, and Krishnan, KR. "The effect of major depression on functional status in patients with coronary artery disease." J Am Geriatr Soc 47, no. 3 (March 1999): 319-322. Link to Item
  - Bart, BA, and O'Connor, CM. "Clinical determinants of mortality in patients with cardiomyopathy." Cardiology Review 16, no. 7 (1999): 8-11.
  - Carlo, CHD, and O'Connor, CM. "Cardiac troponins in congestive heart failure." American Heart Journal 138, no. 4 I (1999): 646-653. Full Text
  - McKenzie, ME, Pothula, A, Gurbel, PA, Fuzaylov, SY, O'Connor, CM, Gattis, WA, and Serebruany, VL. "Failure of thrombin generation markers to triage patients presenting with chest pain." Cardiology 92, no. 1 (1999): 53-58. (Academic Article)
  - O'Connor, CM, Gattis, WA, Gheorghiade, M, Granger, CB, Gilbert, J, McKenney, JM, Messineo, FC, Burnett, JC, Katz, SD, Elkayam, U, Kasper, EK, Goldstein, S, Cody, RJ, and Massie, BM. "A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: The U.S. Ecadotril Pilot Safety Study." American Heart Journal 138, no. 6 I (January 1, 1999): 1140-1148. Full Text
  - O'Connor, CM, Gattis, WA, Uretsky, BF, Adams, J, McNulty, SE, Grossman, SH, McKenna, WJ, Zannad, F, Swedberg, K, Gheorghiade, M, and Califf, RM. "Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: Insights from the Flolan International Randomized Survival Trial (FIRST)." American Heart Journal 138, no. 1 I (January 1, 1999): 78-86. Full Text
  - Orloff, DG, Blazing, MA, and O'Connor, CM. "Atherosclerotic disease in non-insulin-dependent diabetes mellitus: Role of abnormal lipids and the place for lipid-altering therapies." American Heart Journal 138, no. 5 I (January 1, 1999). Full Text
  - Shapiro, PA, Lespérance, F, Frasure-Smith, N, O'Connor, CM, Baker, B, Jiang, JW, Dorian, P, Harrison, W, and Glassman, AH. "An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT trial)." American Heart Journal 137, no. 6 (January 1, 1999): 1100-1106. Full Text
  - Thel, MC, and O'Connor, CM. "Cardiopulmonary resuscitation: historical perspective to recent investigations." Am Heart J 137, no. 1 (January 1999): 39-48. (Review) Link to Item
  - Velazquez, EJ, and O'Connor, CM. "Heart failure after myocardial infarction: A good heart is hard to find." American Heart Journal 138, no. 6 I (January 1, 1999): 1009-1011. Full Text
  - O'Connor, CM, Carson, PE, Miller, AB, Pressler, ML, Belkin, RN, Neuberg, GW, Frid, DJ, Cropp, AB, Anderson, S, Wertheimer, JH, and DeMets, DL. "Effect of amlodipine on mode of death among patients with advanced heart failure in the PRAISE trial. Prospective Randomized Amlodipine Survival Evaluation." Am J Cardiol 82, no. 7 (October 1, 1998): 881-887. Link to Item
  - O'Connor, CM, Carson, PE, Miller, AB, Pressler, ML, Belkin, RN, Neuberg, GW, Frid, DJ, Cropp, AB, Anderson, S, Wertheimer, JH, and DeMets, DL. "Effect of amlodipine on mode of death among patients with advanced heart failure in the PRAISE trial." American Journal of Cardiology 82, no. 7 (October 1, 1998): 881-887. Full Text
  - Guyton, JR, Goldberg, AC, Kreisberg, RA, Sprecher, DL, Superko, HR, and O'Connor, CM. "Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia." Am J Cardiol 82, no. 6 (September 15, 1998): 737-743. Link to Item
  - Krishnan, KR, George, LK, Pieper, CF, Jiang, W, Arias, R, Look, A, and O'Connor, C. "Depression and social support in elderly patients with cardiac disease." American Heart Journal 136, no. 3 (September 1998): 491-495. Full Text
  - Shah, BR, Lin, C, Maynard, C, Bart, B, Selvester, RH, Shaw, LK, O'Connor, C, and Wagner, GS. "Specificity of electrocardiographic myocardial infarction screening criteria in patients with nonischemic cardiomyopathies." Am Heart J 136, no. 2 (August 1998): 314-319. Full Text Link to Item
  - Gattis, WA, Larsen, RL, Hasselblad, V, Bart, BA, and O'Connor, CM. "Is optimal angiotensin-converting enzyme inhibitor dosing neglected in elderly patients with heart failure?." Am Heart J 136, no. 1 (July 1998): 43-48. Link to Item
  - Serebruany, VL, Bahr, RD, O'Connor, CM, Lowry, DR, and Gurbel, PA. "Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction. The GUSTO-III Platelet Substudy." Cardiology 90, no. 1 (July 1998): 37-42. Full Text
  - Serebruany, VL, Bahr, RD, O'Connor, CM, Lowry, DR, and Gurbel, PA. "Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction." Cardiology 90, no. 1 (July 1, 1998): 37-42. Full Text
  - O'Connor, CM, Gattis, WA, and Swedberg, K. "Current and novel pharmacologic approaches in advanced heart failure." Am Heart J 135, no. 6 Pt 2 Su (June 1998): S249-S263. (Review) Link to Item
  - Flack, JM, O'Connor, CM, and Wei, JY. "Four commonly seen cardiovascular diseases." Patient Care 32, no. 9 (May 15, 1998): 98-130.
  - Hassan, TB, and Barnett, DB. "Magnesium in in-hospital cardiac arrest." Lancet (London, England) 351, no. 9100 (February 1998): 445-446. (Letter) Full Text
  - O'Connor, CM, Gattis, WA, and Swedberg, K. "Current and novel pharmacologic approaches in advanced heart failure." American Heart Journal 135, no. 6 II SUPPL. (January 1, 1998). (Review)
  - Serebruany, VL, Atar, D, Dalesandro, MR, O'Connor, CM, and Gurbel, PA. "Changes in hemostasis after parenteral magnesium in myocardial ischemia-reperfusion: From animal studies to clinical trials." Magnesium Research 11, no. 2 (1998): 133-140.
  - Cuffe, MS, and O'Connor, CM. "Pharmacologic management of acute heart failure." Current Opinion in Critical Care 3, no. 5 (December 1, 1997): 386-390.
  - Blumenthal, JA, O'Connor, C, Hinderliter, A, Fath, K, Hegde, SB, Miller, G, Puma, J, Sessions, W, Sheps, D, Zakhary, B, and Williams, RB. "Psychosocial factors and coronary disease. A national multicenter clinical trial (ENRICHD) with a North Carolina focus." North Carolina Medical Journal 58, no. 6 (November 1997): 440-444. (Review)
  - Thel, MC, Armstrong, AL, McNulty, SE, Califf, RM, and O'Connor, CM. "Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff." Lancet 350, no. 9087 (November 1, 1997): 1272-1276. Link to Item
  - Thel, MC, Armstrong, AL, McNulty, SE, Califf, RM, and O'Connor, CM. "Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff." Lancet (London, England) 350, no. 9087 (November 1997): 1272-1276. Full Text
  - Bart, BA, Shaw, LK, McCants, CB, Fortin, DF, Lee, KL, Califf, RM, and O'Connor, CM. "Clinical determinants of mortality in patients with angiographically diagnosed ischemic or nonischemic cardiomyopathy." Journal of the American College of Cardiology 30, no. 4 (October 1997): 1002-1008. Full Text
  - Blumenthal, JA, Jiang, W, Babyak, MA, Krantz, DS, Frid, DJ, Coleman, RE, Waugh, R, Hanson, M, Appelbaum, M, O'Connor, C, and Morris, JJ. "Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms." Archives of Internal Medicine 157, no. 19 (October 1997): 2213-2223. Full Text
  - Jiang, W, Hathaway, WR, McNulty, S, Larsen, RL, Hansley, KL, Zhang, Y, and O'Connor, CM. "Ability of heart rate variability to predict prognosis in patients with advanced congestive heart failure." Am J Cardiol 80, no. 6 (September 15, 1997): 808-811. Link to Item
  - Hayano, J, Jiang, W, Waugh, R, O'Connor, C, Frid, D, and Blumenthal, JA. "Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease." Am Heart J 134, no. 3 (September 1997): 411-418. Link to Item
  - O'Connor, CM, Hathaway, WR, Bates, ER, Leimberger, JD, Sigmon, KN, Kereiakes, DJ, George, BS, Samaha, JK, Abbottsmith, CW, Candela, RJ, Topol, EJ, and Califf, RM. "Clinical characteristics and long-term outcome of patients in whom congestive heart failure develops after thrombolytic therapy for acute myocardial infarction: development of a predictive model." American Heart Journal 133, no. 6 (June 1997): 663-673. Full Text
  - Gullette, EC, Blumenthal, JA, Babyak, M, Jiang, W, Waugh, RA, Frid, DJ, O'Connor, CM, Morris, JJ, and Krantz, DS. "Effects of mental stress on myocardial ischemia during daily life." Jama 277, no. 19 (May 1997): 1521-1526. Full Text
  - Bart, BA, Gattis, WA, Diem, SJ, and O'Connor, CM. "Reasons for underuse of angiotensin-converting enzyme inhibitors in patients with heart failure and left ventricular dysfunction." Am J Cardiol 79, no. 8 (April 15, 1997): 1118-1120. Link to Item
  - Poole-Wilson, PA, Bobbio, M, Allan, JJ, Packer, M, O'Connor, CM, and Demets, DL. "Amlodipine in chronic heart failure (multiple letters) [2]." New England Journal of Medicine 336, no. 14 (1997): 1023-1024. Full Text
  - Gonzalez, MB, Snyderman, TB, Colket, JT, Arias, RM, Jiang, JW, O'Connor, CM, and Krishnan, KR. "Depression in patients with coronary artery disease." Depression 4, no. 2 (December 1, 1996): 57-62. Full Text
  - Packer, M, O'Connor, CM, Ghali, JK, Pressler, ML, Carson, PE, Belkin, RN, Miller, AB, Neuberg, GW, Frid, D, Wertheimer, JH, Cropp, AB, and DeMets, DL. "Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group." The New England Journal of Medicine 335, no. 15 (October 1996): 1107-1114. Full Text
  - Barefoot, JC, Helms, MJ, Mark, DB, Blumenthal, JA, Califf, RM, Haney, TL, O'Connor, CM, Siegler, IC, and Williams, RB. "Depression and long-term mortality risk in patients with coronary artery disease." The American Journal of Cardiology 78, no. 6 (September 1996): 613-617. Full Text
  - Jiang, W, Babyak, M, Krantz, DS, Waugh, RA, Coleman, RE, Hanson, MM, Frid, DJ, McNulty, S, Morris, JJ, O'Connor, CM, and Blumenthal, JA. "Mental stress--induced myocardial ischemia and cardiac events." Jama 275, no. 21 (June 1996): 1651-1656. Full Text
  - O'Connor, CM, Meese, RB, McNulty, S, Lucas, KD, Carney, RJ, LeBoeuf, RM, Maddox, W, Bethea, CF, Shadoff, N, Trahey, TF, Heinsimer, JA, Burks, JM, O'Donnell, G, Krucoff, MW, and Califf, RM. "A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction. The DUCCS-II Investigators." The American Journal of Cardiology 77, no. 10 (April 1996): 791-797. Full Text
  - Mahaffey, KW, Granger, CB, Collins, R, O'Connor, CM, Ohman, EM, Bleich, SD, Col, JJ, and Califf, RM. "Overview of randomized trials of intravenous heparin in patients with acute myocardial infarction treated with thrombolytic therapy." The American Journal of Cardiology 77, no. 8 (March 1996): 551-556. Full Text
  - Gonzalez, MB, Snyderman, TB, Colket, JT, Arias, RM, Jiang, JW, O'Connor, CM, and Krishnan, KR. "Depression in patients with coronary artery disease." Depression 4, no. 2 (January 1996): 57-62. Full Text
  - Jiang, W, Trauner, MA, Coleman, RE, Waugh, RA, Hanson, MW, Frid, DJ, Phillips, BG, Morris, JJ, O'Connor, C, and Blumenthal, JA. "Association of physical fitness and transient myocardial ischemia in patients with coronary artery disease." J Cardiopulm Rehabil 15, no. 6 (November 1995): 431-438. Link to Item
  - Blumenthal, JA, Jiang, W, Waugh, RA, Frid, DJ, Morris, JJ, Coleman, RE, Hanson, M, Babyak, M, Thyrum, ET, and Krantz, DS. "Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life. Association and hemodynamic features." Circulation 92, no. 8 (October 1995): 2102-2108. Full Text
  - Thel, MC, and O'Connor, CM. "Magnesium in acute myocardial infarction." Coron Artery Dis 6, no. 10 (October 1995): 831-837. (Review) Link to Item
  - Jiang, W, Blumenthal, JA, Hanson, MW, Coleman, RE, O'Connor, CM, Frid, D, Morris, JJ, and Waugh, RA. "Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring." The American Journal of Cardiology 76, no. 5 (August 1995): 350-354. Full Text
  - Gurbel, PA, and O'Connor, CM. "Zofenopril after anterior myocardial infarction." The New England journal of medicine 332, no. 25 (June 1995): 1715-. (Academic Article) Full Text
  - Campbell, PT, Li, JS, Wall, TC, O'Connor, CM, Van Trigt, P, Kenney, RT, Melhus, O, and Corey, GR. "Cytomegalovirus pericarditis: a case series and review of the literature." Am J Med Sci 309, no. 4 (April 1995): 229-234. Link to Item
  - Gurbel, PA, and O'Connor, CM. "Zofenopril after anterior myocardial infarction." New England Journal of Medicine 332, no. 25 (1995): 1715--.
  - Selker, HP, Beshansky, JR, Schmid, CH, Griffith, JL, Longstreth, WT, O'Connor, CM, Caplan, LR, Massey, EW, D'Agostino, RB, and Laks, MM. "Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results." Circulation 90, no. 4 (October 1994): 1657-1661. Link to Item
  - Larsen, RL, Behar, VS, Brazer, SR, Chen, J, and O'Connor, CM. "Chest pain presenting as ischemic heart disease. Congenital absence of the pericardium." N C Med J 55, no. 7 (July 1994): 306-308. Link to Item
  - O'Connor, CM, Meese, R, Carney, R, Smith, J, Conn, E, Burks, J, Hartman, C, Roark, S, Shadoff, N, and Heard, M. "A randomized trial of intravenous heparin in conjunction with anistreplase (anisoylated plasminogen streptokinase activator complex) in acute myocardial infarction: the Duke University Clinical Cardiology Study (DUCCS) 1." Journal of the American College of Cardiology 23, no. 1 (January 1994): 11-18. Full Text
  - Selker, HP, Beshansky, JR, Schmid, CH, Griffith, JL, Longstreth, WT, O'Connor, CM, Caplan, LR, Massey, EW, D'Agostino, RB, Laks, MM, Lee, KL, Maynard, C, Wagner, GS, Weaver, WD, and Califf, RM. "Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage: Thrombolytic Predictive Instrument (TPI) project results." Circulation 90, no. 4 I (January 1, 1994): 1657-1661. Full Text
  - Van Trigt, P, Douglas, J, Smith, PK, Campbell, PT, Wall, TC, Kenney, RT, O'Connor, CM, Sheikh, KH, and Corey, GR. "A prospective trial of subxiphoid pericardiotomy in the diagnosis and treatment of large pericardial effusion. A follow-up report." Ann Surg 218, no. 6 (December 1993): 777-782. Link to Item
  - Jiang, W, Hayano, J, Coleman, ER, Hanson, MW, Frid, DJ, O'Connor, C, Thurber, D, Waugh, RA, and Blumenthal, JA. "Relation of cardiovascular responses to mental stress and cardiac vagal activity in coronary artery disease." The American Journal of Cardiology 72, no. 7 (September 1993): 551-554. Full Text
  - Corey, GR, Campbell, PT, Van Trigt, P, Kenney, RT, O'Connor, CM, Sheikh, KH, Kisslo, JA, and Wall, TC. "Etiology of large pericardial effusions." Am J Med 95, no. 2 (August 1993): 209-213. Link to Item
  - Kenney, RT, Li, JS, Clyde, WA, Wall, TC, O'Connor, CM, Campbell, PT, Van Trigt, P, and Corey, GR. "Mycoplasmal pericarditis: evidence of invasive disease." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 17 Suppl 1 (August 1993): S58-S62. (Review) Full Text
  - Krucoff, MW, Croll, MA, Pope, JE, Granger, CB, O'Connor, CM, Sigmon, KN, Wagner, BL, Ryan, JA, Lee, KL, and Kereiakes, DJ. "Continuous 12-lead ST-segment recovery analysis in the TAMI 7 study. Performance of a noninvasive method for real-time detection of failed myocardial reperfusion." Circulation 88, no. 2 (August 1993): 437-446. Full Text
  - Koenig, HG, O'Connor, CM, Guarisco, SA, Zabel, KM, and Ford, SM. "Depressive Disorder in Older Medical Inpatients on General Medicine and Cardiology Services at a University Teaching Hospital." The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 1, no. 3 (June 1993): 197-210. Full Text
  - Slaughter, TF, Mody, EA, Oldham, HN, Reves, JG, O'Connor, CM, Parker, JK, and Greenberg, CS. "Management of a patient with type IIC von Willebrand's disease during coronary artery bypass graft surgery." Anesthesiology 78, no. 1 (January 1993): 195-197. Link to Item
  - Wall, TC, Campbell, PT, O'Connor, CM, Van Trigt, P, Kenney, RT, Sheikh, KH, Kisslo, JA, and Corey, GR. "Diagnosis and management (by subxiphoid pericardiotomy) of large pericardial effusions causing cardiac tamponade." Am J Cardiol 69, no. 12 (April 15, 1992): 1075-1078. Link to Item
  - Campbell, PT, Van Trigt, P, Wall, TC, Kenney, RT, O'Connor, CM, Sheikh, KH, Kisslo, JA, Baker, ME, and Corey, GR. "Subxiphoid pericardiotomy in the diagnosis and management of large pericardial effusions associated with malignancy." Chest 101, no. 4 (April 1992): 938-943. Link to Item
  - Ortel, TL, Gockerman, JP, Califf, RM, McCann, RL, O'Connor, CM, Metzler, DM, and Greenberg, CS. "Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis." Thrombosis and Haemostasis 67, no. 3 (March 1992): 292-296.
  - O'Connor, CM, and Califf, RM. "Aggressive therapy of acute MI in the elderly." Hospital Practice (Office Ed.) 27, no. 2 (February 1992): 59-passim. Full Text
  - Uglietta, JP, O'Connor, CM, Boyko, OB, Aldrich, H, Massey, EW, and Heinz, ER. "CT patterns of intracranial hemorrhage complicating thrombolytic therapy for acute myocardial infarction." Radiology 181, no. 2 (November 1991): 555-559. Full Text Link to Item
  - Wallis, DE, Boden, WE, Califf, R, Crawford, MH, Hakki, AH, Iskandrian, AS, Labovitz, A, O'Connor, C, Sutton, R, and Scanlon, PJ. "Failure of adjuvant heparin to reduce myocardial ischemia in the early treatment of patients with unstable angina." American Heart Journal 122, no. 4 Pt 1 (October 1991): 949-954. Full Text
  - O'Connor, CM, Califf, RM, Massey, EW, Mark, DB, Kereiakes, DJ, Candela, RJ, Abbottsmith, C, George, B, Stack, RS, and Aronson, L. "Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis." Journal of the American College of Cardiology 16, no. 3 (September 1990): 533-540. Full Text
  - Blumenthal, JA, and O'Connor, C. "Stress and silent myocardial ischemia. A new research study at Duke University Medical Center." N C Med J 51, no. 4 (April 1990): 135-138. Link to Item
  - Mark, DB, Hlatky, MA, O'Connor, CM, Pryor, DB, Wall, TC, Honan, MB, Phillips, HR, and Califf, RM. "Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues." Journal of the American College of Cardiology 12, no. 6 Suppl A (December 1988): 32A-43A. Full Text
  - Stack, RS, Califf, RM, Hinohara, T, Phillips, HR, Pryor, DB, Simonton, CA, Carlson, EB, Morris, KG, Behar, VS, and Kong, Y. "Survival and cardiac event rates in the first year after emergency coronary angioplasty for acute myocardial infarction." Journal of the American College of Cardiology 11, no. 6 (June 1988): 1141-1149. Full Text
  - Simonton, CA, Mark, DB, Hinohara, T, Rendall, DS, Phillips, HR, Peter, RH, Behar, VS, Kong, Y, O'Callaghan, WG, and O'Connor, C. "Late restenosis after emergent coronary angioplasty for acute myocardial infarction: comparison with elective coronary angioplasty." Journal of the American College of Cardiology 11, no. 4 (April 1988): 698-705. Full Text
  - Hlatky, MA, Cotugno, H, O'Connor, C, Mark, DB, Pryor, DB, and Califf, RM. "Adoption of thrombolytic therapy in the management of acute myocardial infarction." The American Journal of Cardiology 61, no. 8 (March 1988): 510-514. Full Text
  - Hlatky, MA, Cotugno, HE, Mark, DB, O'Connor, C, Califf, RM, and Pryor, DB. "Trends in physician management of uncomplicated acute myocardial infarction, 1970 to 1987." The American Journal of Cardiology 61, no. 8 (March 1988): 515-518. Full Text
  - Stack, RS, O'Connor, CM, Mark, DB, Hinohara, T, Phillips, HR, Lee, MM, Ramirez, NM, O'Callaghan, WG, Simonton, CA, and Carlson, EB. "Coronary perfusion during acute myocardial infarction with a combined therapy of coronary angioplasty and high-dose intravenous streptokinase." Circulation 77, no. 1 (January 1988): 151-161. Full Text
  - Boswick, JM, Lee, KL, Aronson, LG, O'Connor, CM, Honan, MB, Califf, RM, and Pryor, DB. "USE OF COMPUTERIZED STATISTICAL MODELS TO EDUCATE MEDICAL HOUSESTAFF IN ESTIMATING CLINICAL OUTCOMES." Proceedings Annual Symposium on Computer Applications in Medical Care (December 1, 1987): 162-165.
  - Patronas, NJ, Di Chiro, G, Brooks, RA, DeLaPaz, RL, Kornblith, PL, Smith, BH, Rizzoli, HV, Kessler, RM, Manning, RG, Channing, M, Wolf, AP, and O'Connor, CM. "Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain." Radiology 144, no. 4 (September 1982): 885-889. Full Text
  - Brooks, RA, Mitchell, LG, O'Connor, CM, and Di Chiro, G. "On the relationship between computed tomography numbers and specific gravity." Phys Med Biol 26, no. 1 (January 1981): 141-147. Link to Item
  - Rieth, KG, Fujiwara, K, Di Chiro, G, Klatzo, I, Brooks, RA, Johnston, GS, O'Connor, CM, and Mitchell, LG. "Serial measurements of CT attenuation and specific gravity in experimental cerebral edema." Radiology 135, no. 2 (May 1980): 343-348. Full Text
  - Sheridan, WT, Keller, MR, O'Connor, CM, Brooks, RA, and Hanson, KM. "Evaluation of edge-induced streaking artifacts in CT scanners." Med Phys 7, no. 2 (March 1980): 108-111. Full Text Link to Item
- Conference Papers
  - Mentz, RJ, O'Connor, CM, Granger, BB, Yang, H, Patel, CB, Steinhauser, KE, Fiuzat, M, Johnson, KS, Anstrom, KJ, Dodson, GC, Taylor, DH, Mark, DB, Tulsky, JA, and Rogers, JG. "Palliative care and hospital readmissions in patients with advanced heart failure: Insights from the PAL-HF trial." October 2018. Full Text
  - Pokorney, SD, Al-Khatib, SM, Sun, J-L, Schulte, P, O'Connor, CM, Teerlink, JR, Armstrong, PW, Ezekowitz, JA, Starling, RC, Voors, AA, Velazquez, EJ, Hernandez, AF, and Mentz, RJ. "Sudden cardiac death after acute heart failure hospital admission: insights from ASCEND-HF." March 2018. Full Text
  - DeVore, AD, Hasselblad, V, Mentz, RJ, O'Connor, CM, Armstrong, PW, McMurray, JJ, Ezekowitz, JA, Tang, WHW, Starling, RC, Voors, AA, Califf, RM, and Hernandez, AF. "Loop diuretic dose adjustments after a hospitalization for heart failure: insights from ASCEND-HF." March 2015. Full Text
  - Valente, MAE, Voors, AA, Damman, K, Van Veldhuisen, DJ, Massie, BM, O'Connor, CM, Metra, M, Ponikowski, P, Teerlink, JR, Cotter, G, Davison, B, Cleland, JGF, Givertz, MM, Bloomfield, DM, Fiuzat, M, Dittrich, HC, and Hillege, HL. "Diuretic response in acute heart failure: clinical characteristics and prognostic significance." May 2014. Full Text
  - Carson, P, Wertheimer, J, Miller, A, O'Connor, CM, Pina, IL, Selzman, C, Sueta, C, She, L, Greene, D, Lee, KL, Jones, RH, and Velazquez, EJ. "Surgical Treatment for Ischemic Heart Failure (STICH) Trial: Mode of Death Results." October 2013. Full Text
  - Wilcox, JE, Fonarow, GC, Zhang, Y, Albert, NM, Curtis, AB, Gheorghiade, M, Heywood, JT, Mehra, MR, O'Connor, CM, Walsh, MN, Reynolds, D, and Yancy, CW. "Clinical Effectiveness of CRT and ICD Therapy in Men and Women with Heart Failure: Findings from IMPROVE HF." August 2013. Full Text Link to Item
Teaching & Mentoring
Recent Courses
- CRSP 301B: Research in Clinical Research 2019

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