Overview
Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.
Current Appointments & Affiliations
Adjunct Professor in the Department of Medicine
·
2016 - Present
Medicine, Clinical Pharmacology,
Medicine
Recent Publications
Effect of Vericiguat on Total Heart Failure Events in Compensated Outpatients With HFrEF: Insights From VICTOR.
Journal Article J Am Coll Cardiol · December 16, 2025 BACKGROUND: In the VICTOR (Vericiguat Global Study in Participants With Chronic Heart Failure) trial, in a contemporary ambulatory cohort with heart failure and reduced ejection fraction (HFrEF) and no recent hospitalization, the primary outcome of hospita ... Full text Link to item CiteTwo-year outcomes in the direct oral anticoagulant apixaban in left ventricular assist devices (DOAC LVAD) study.
Journal Article J Heart Lung Transplant · December 2025 Anticoagulation with apixaban was previously demonstrated to be feasible without excess hemocompatibility-related adverse events (HRAEs) at 6 months but longer-term data on use of apixaban is lacking. We report 2-year outcomes of patients enrolled into the ... Full text Link to item CiteGeographic region variation in patient characteristics, clinical outcomes and treatment of HFrEF in the VICTORIA trial.
Journal Article ESC Heart Fail · December 2025 AIMS: Heterogeneity in demographics, aetiology, healthcare access and guideline-directed medical therapy (GDMT), and survival bias of patients with heart failure with reduced ejection fraction (HFrEF) is evident from international trials and registries. Th ... Full text Link to item CiteRecent Grants
Duke-UNC Clinical Hematology and Transfusion Research Career Development Program
ResearchMentor · Awarded by National Institutes of Health · 2006 - 2019STICHES
Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2011 - 2019GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC)
ResearchCo Investigator · Awarded by National Institutes of Health · 2012 - 2017View All Grants
Education, Training & Certifications
University of Maryland, College Park ·
1983
M.D.