Scholars@Duke

Bhatt, Ankeet S., Mona Fiuzat, JoAnn Lindenfeld, Christopher M. O’Connor, and Javed Butler. “Reply: Improving Heart Failure Therapeutics: Thinking Outside the Pillbox?” Jacc Heart Fail 9, no. 4 (April 2021): 320–21. https://doi.org/10.1016/j.jchf.2021.01.005.

O’Connor, Christopher M. “Heart Failure Leadership, Culture, and Governance: Lessons Learned From Tom Brady.” Jacc Heart Fail 9, no. 4 (April 2021): 317–18. https://doi.org/10.1016/j.jchf.2021.02.002.

Brooksbank, Jeremy A., Stephen J. Greene, Hailey M. Harris, Amanda Stebbins, Mona Fiuzat, David J. Whellan, Brooke Alhanti, et al. “Beta-blocker and ACE-inhibitor dosing as a function of body surface area: From the HF-ACTION trial.” Am Heart J 233 (March 2021): 1–4. https://doi.org/10.1016/j.ahj.2020.11.003.

Fudim, Marat, Joseph B. Lerman, Courtney Page, Brooke Alhanti, Robert M. Califf, Justin A. Ezekowitz, Nicolas Girerd, et al. “Plasma Volume Status and Its Association With In-Hospital and Postdischarge Outcomes in Decompensated Heart Failure.” J Card Fail 27, no. 3 (March 2021): 297–308. https://doi.org/10.1016/j.cardfail.2020.09.478.

O’Connor, Christopher M. “Reviewers Hall of Fame: 2020 Top Reviewers.” Jacc Heart Fail 9, no. 3 (March 2021): 241. https://doi.org/10.1016/j.jchf.2021.01.004.

Batchelor, Wayne B., Abdulla A. Damluji, Celina Yong, Mona Fiuzat, Scott D. Barnett, David E. Kandzari, Matthew W. Sherwood, et al. “Does study subject diversity influence cardiology research site performance?: Insights from 2 U.S. National Coronary Stent Registries.” Am Heart J 236 (February 24, 2021): 37–48. https://doi.org/10.1016/j.ahj.2021.02.003.

Lang, Ninian N., Faheem A. Ahmad, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jorg Taubel, et al. “Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial.” Eur J Heart Fail, February 23, 2021. https://doi.org/10.1002/ejhf.2138.

Yang, Siyun, Monique Anderson Starks, Adrian F. Hernandez, Elizabeth L. Turner, Robert M. Califf, Christopher M. O’Connor, Robert J. Mentz, and Kingshuk Roy Choudhury. “Corrigendum to "Impact of baseline covariate imbalance on bias in treatment effect estimation in cluster randomized trials: Race as an example" [Contemporary Clinical Trials volume 88 (2020) 105775].” Contemp Clin Trials 103 (February 9, 2021): 106298. https://doi.org/10.1016/j.cct.2021.106298.

Felker, G Michael, John J. V. McMurray, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jan Belohlavek, et al. “Effects of a Novel Nitroxyl Donor in Acute Heart Failure: The STAND-UP AHF Study.” Jacc Heart Fail 9, no. 2 (February 2021): 146–57. https://doi.org/10.1016/j.jchf.2020.10.012.

O’Connor, Christopher M. “Meet Me in the Middle: Lessons From the Cardiorenal Advisory Committee for Sacubitril/Valsartan in HFpEF.” Jacc Heart Fail 9, no. 2 (February 2021): 161–63. https://doi.org/10.1016/j.jchf.2020.12.003.

Markousis-Mavrogenis, George, Jasper Tromp, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “The Additive Prognostic Value of Serial Plasma Interleukin-6 Levels over Changes in Brain Natriuretic Peptide in Patients with Acute Heart Failure.” J Card Fail, January 23, 2021. https://doi.org/10.1016/j.cardfail.2021.01.008.

Perez, Antonio L., Justin L. Grodin, Thanat Chaikijurajai, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, et al. “Interleukin-6 and Outcomes in Acute Heart Failure: An ASCEND-HF Substudy.” J Card Fail, January 23, 2021. https://doi.org/10.1016/j.cardfail.2021.01.006.

Farsky, Pedro S., Jennifer White, Hussein R. Al-Khalidi, Carla A. Sueta, Jean L. Rouleau, Julio A. Panza, Eric J. Velazquez, Christopher M. O’Connor, and Christopher M. Working Group and Surgical Treatment for IsChemic Heart failure Trial Investigators. “Optimal medical therapy with or without surgical revascularization and long-term outcomes in ischemic cardiomyopathy.” J Thorac Cardiovasc Surg, January 7, 2021. https://doi.org/10.1016/j.jtcvs.2020.12.094.

Bhatt, Ankeet S., William T. Abraham, JoAnn Lindenfeld, Michael Bristow, Peter E. Carson, G Michael Felker, Gregg C. Fonarow, et al. “Treatment of HF in an Era of Multiple Therapies: Statement From the HF Collaboratory.” Jacc Heart Fail 9, no. 1 (January 2021): 1–12. https://doi.org/10.1016/j.jchf.2020.10.014.

O’Connor, Christopher M. “A Generation Passed; A Generation Forward: Why Joseph C. Greenfield, Chairman of Medicine, Duke University, Matters Today (1931 to 2020).” Jacc Heart Fail 9, no. 1 (January 2021): 80–81. https://doi.org/10.1016/j.jchf.2020.11.005.

Abraham, William T., Mitchell A. Psotka, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Roxana Mehran, Amrut V. Ambardekar, et al. “Standardized definitions for evaluation of heart failure therapies: scientific expert panel from the Heart Failure Collaboratory and Academic Research Consortium.” Eur J Heart Fail 22, no. 12 (December 2020): 2175–86. https://doi.org/10.1002/ejhf.2018.

Angraal, Suveen, César Caraballo, Peter Kahn, Ambika Bhatnagar, Bikramjot Singh, F Perry Wilson, Mona Fiuzat, et al. “Geographical affiliation with top 10 NIH-funded academic medical centers and differences between mortality from cardiovascular disease and cancer.” Am Heart J 230 (December 2020): 54–58. https://doi.org/10.1016/j.ahj.2020.08.014.

Lanfear, David E., Jasmine A. Luzum, Ruicong She, Hongsheng Gui, Mark P. Donahue, Christopher M. O’Connor, Kirkwood F. Adams, et al. “Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure.” Circ Heart Fail 13, no. 12 (December 2020): e007012. https://doi.org/10.1161/CIRCHEARTFAILURE.119.007012.

O’Connor, Christopher M., and Michael R. Bristow. “Changing U.S. Heart Failure Research Culture: Part 2-Recognizing Frontline Investigators and Coordinators.” Jacc Heart Fail 8, no. 12 (December 2020): 1050–51. https://doi.org/10.1016/j.jchf.2020.10.010.

Perego, Carlotta, Marco Sbolli, Claudia Specchia, Mona Fiuzat, Zachary R. McCaw, Marco Metra, Chiara Oriecuia, et al. “Utility of Restricted Mean Survival Time Analysis for Heart Failure Clinical Trial Evaluation and Interpretation.” Jacc Heart Fail 8, no. 12 (December 2020): 973–83. https://doi.org/10.1016/j.jchf.2020.07.005.

Sbolli, Marco, and Christopher M. O’Connor. “Aldosterone: Behind the Scenes of Depression and Heart Failure?” Jacc Heart Fail 8, no. 12 (December 2020): 1021–23. https://doi.org/10.1016/j.jchf.2020.10.006.

Psotka, Mitchell A., William T. Abraham, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Tariq Ahmad, Ankeet S. Bhatt, et al. “Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.” J Am Coll Cardiol 76, no. 20 (November 17, 2020): 2368–78. https://doi.org/10.1016/j.jacc.2020.09.544.

Lam, Carolyn S. P., Anna Giczewska, Karen Sliwa, Frank Edelmann, Jens Refsgaard, Edimar Bocchi, Justin A. Ezekowitz, et al. “Clinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights From the VICTORIA Trial.” Jama Cardiol, November 13, 2020. https://doi.org/10.1001/jamacardio.2020.6455.

Ezekowitz, Justin A., Christopher M. O’Connor, Richard W. Troughton, Wendimagegn G. Alemayehu, Cynthia M. Westerhout, Adriaan A. Voors, Javed Butler, et al. “N-Terminal Pro-B-Type Natriuretic Peptide and Clinical Outcomes: Vericiguat Heart Failure With Reduced Ejection Fraction Study.” Jacc Heart Fail 8, no. 11 (November 2020): 931–39. https://doi.org/10.1016/j.jchf.2020.08.008.

O’Connor, Christopher M. “Personalized Therapeutic Approach: Gun Control for Shotgun Therapy.” Jacc Heart Fail 8, no. 11 (November 2020): 954–55. https://doi.org/10.1016/j.jchf.2020.09.002.

Sbolli, Marco, Mona Fiuzat, Dario Cani, and Christopher M. O’Connor. “Depression and heart failure: the lonely comorbidity.” Eur J Heart Fail 22, no. 11 (November 2020): 2007–17. https://doi.org/10.1002/ejhf.1865.

Armstrong, Paul W., Carolyn S. P. Lam, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Burkert Pieske, et al. “Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial.” Jama 324, no. 15 (October 20, 2020): 1512–21. https://doi.org/10.1001/jama.2020.15922.

Armstrong, Paul W., Kevin J. Anstrom, Christopher M. O’Connor, and Christopher M. VICTORIA Study Group. “Vericiguat in Heart Failure with Reduced Ejection Fraction. Reply.” N Engl J Med 383, no. 15 (October 8, 2020): 1497–98. https://doi.org/10.1056/NEJMc2027731.

Psotka, Mitchell A., Mona Fiuzat, Marco Metra, and Christopher M. O’Connor. “Reply: Potential Mechanisms to Improve Heart Failure Clinical Trial Publication Rates.” J Am Coll Cardiol 76, no. 14 (October 6, 2020): 1717–18. https://doi.org/10.1016/j.jacc.2020.08.013.

Armstrong, Paul W., Burkert Pieske, and Christopher M. O’Connor. “Effects of vericiguat in heart failure with reduced ejection fraction: do not forget sST2. Reply.” Eur J Heart Fail 22, no. 10 (October 2020): 1935. https://doi.org/10.1002/ejhf.1765.

O’Connor, Christopher M. “Convalescence From COVID Research: Lessons From the Heart Failure Community.” Jacc Heart Fail 8, no. 10 (October 2020): 870–71. https://doi.org/10.1016/j.jchf.2020.08.005.

O’Connor, Christopher M., and Cleveland Francis. “The Journey of an American Black Cardiologist.” Jacc Heart Fail 8, no. 9 (September 2020): 780–81. https://doi.org/10.1016/j.jchf.2020.08.001.

Psotka, Mitchell A., Mona Fiuzat, Scott D. Solomon, Cynthia Chauhan, G Michael Felker, Javed Butler, John R. Teerlink, Shashank S. Sinha, Christopher M. O’Connor, and Marvin A. Konstam. “Challenges and Potential Improvements to Patient Access to Pharmaceuticals: Examples From Cardiology.” Circulation 142, no. 8 (August 24, 2020): 790–98. https://doi.org/10.1161/circulationaha.119.044976.

Abraham, William T., Mona Fiuzat, Mitchell A. Psotka, and Christopher M. O’Connor. “Heart Failure Collaboratory Statement on Remote Monitoring and Social Distancing in the Landscape of COVID-19.” Jacc Heart Fail 8, no. 8 (August 2020): 692–94. https://doi.org/10.1016/j.jchf.2020.06.006.

Damluji, Abdulla A., Michael Fabbro, Richard H. Epstein, Stefan Rayer, Ying Wang, Mauro Moscucci, Mauricio G. Cohen, et al. “Transcatheter Aortic Valve Replacement in Low-Population Density Areas: Assessing Healthcare Access for Older Adults With Severe Aortic Stenosis.” Circ Cardiovasc Qual Outcomes 13, no. 8 (August 2020): e006245. https://doi.org/10.1161/CIRCOUTCOMES.119.006245.

Reza, Nosheen, Ayman Samman Tahhan, Nadim Mahmud, Ersilia M. DeFilippis, Alaaeddin Alrohaibani, Muthiah Vaduganathan, Stephen J. Greene, et al. “Representation of Women Authors in International Heart Failure Guidelines and Contemporary Clinical Trials.” Circ Heart Fail 13, no. 8 (August 2020): e006605. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006605.

Fiuzat, Mona, Justin Ezekowitz, Wendimagegn Alemayehu, Cynthia M. Westerhout, Marco Sbolli, Dario Cani, David J. Whellan, et al. “Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial.” Jama Cardiol 5, no. 7 (July 1, 2020): 757–64. https://doi.org/10.1001/jamacardio.2020.0640.

O’Connor, Christopher M. “COVID-19 Fatigue: Not So Fast.” Jacc Heart Fail 8, no. 7 (July 2020): 592–94. https://doi.org/10.1016/j.jchf.2020.06.001.

Psotka, Mitchell A., Federica Latta, Dario Cani, Mona Fiuzat, Marco Sbolli, Scott Barnett, Marco Metra, and Christopher M. O’Connor. “Publication Rates of Heart Failure Clinical Trials Remain Low.” J Am Coll Cardiol 75, no. 25 (June 30, 2020): 3151–61. https://doi.org/10.1016/j.jacc.2020.04.068.

Bhatt, Ankeet S., Andrew P. Ambrosy, Allison Dunning, Adam D. DeVore, Javed Butler, Shelby Reed, Adriaan Voors, et al. “The burden of non-cardiac comorbidities and association with clinical outcomes in an acute heart failure trial - insights from ASCEND-HF.” Eur J Heart Fail 22, no. 6 (June 2020): 1022–31. https://doi.org/10.1002/ejhf.1795.

Damluji, Abdulla A., Gregory Rodriguez, Thomas Noel, Lakerria Davis, Vishal Dahya, Behnam Tehrani, Kelly Epps, et al. “Sarcopenia and health-related quality of life in older adults after transcatheter aortic valve replacement.” Am Heart J 224 (June 2020): 171–81. https://doi.org/10.1016/j.ahj.2020.03.021.

Fiuzat, Mona, Naomi Lowy, Norman Stockbridge, Marco Sbolli, Federica Latta, JoAnn Lindenfeld, Eldrin F. Lewis, et al. “Endpoints in Heart Failure Drug Development: History and Future.” Jacc Heart Fail 8, no. 6 (June 2020): 429–40. https://doi.org/10.1016/j.jchf.2019.12.011.

O’Connor, Christopher M. “Heart Failure Editorial Emergencies in the COVID-19 Era.” Jacc Heart Fail 8, no. 6 (June 2020): 518. https://doi.org/10.1016/j.jchf.2020.04.002.

Armstrong, Paul W., Burkert Pieske, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Javed Butler, Carolyn S. P. Lam, et al. “Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.” N Engl J Med 382, no. 20 (May 14, 2020): 1883–93. https://doi.org/10.1056/NEJMoa1915928.

Reddy, Yogesh N. V., Barry A. Borlaug, Christopher M. O’Connor, and Bernard J. Gersh. “Novel approaches to the management of chronic systolic heart failure: future directions and unanswered questions.” Eur Heart J 41, no. 18 (May 7, 2020): 1764–74. https://doi.org/10.1093/eurheartj/ehz364.

Abraham, William T., Mona Fiuzat, Mitchell A. Psotka, and Christopher M. O’Connor. “Heart Failure Collaboratory Statement on Clinical Trials in the Landscape of COVID-19.” Jacc Heart Fail 8, no. 5 (May 2020): 423–25. https://doi.org/10.1016/j.jchf.2020.03.005.

Butler, Javed, Muhammad Shahzeb Khan, Stefan D. Anker, Gregg C. Fonarow, Raymond J. Kim, Savina Nodari, Christopher M. O’Connor, et al. “Effects of Elamipretide on Left Ventricular Function in Patients With Heart Failure With Reduced Ejection Fraction: The PROGRESS-HF Phase 2 Trial.” J Card Fail 26, no. 5 (May 2020): 429–37. https://doi.org/10.1016/j.cardfail.2020.02.001.

Cooper, Lauren B., Mitchell A. Psotka, Shashank Sinha, Brahmajee K. Nallamothu, Christopher R. deFilippi, Wayne Batchelor, Christopher M. O’Connor, and Abdulla A. Damluji. “Specificity of administrative coding for older adults with acute heart failure hospitalizations.” Am Heart J 223 (May 2020): 1–2. https://doi.org/10.1016/j.ahj.2020.02.004.

Ibrahim, Nasrien E., John C. Burnett, Javed Butler, Alexander Camacho, G Michael Felker, Mona Fiuzat, Christopher O’Connor, et al. “Natriuretic Peptides as Inclusion Criteria in Clinical Trials: A JACC: Heart Failure Position Paper.” Jacc Heart Fail 8, no. 5 (May 2020): 347–58. https://doi.org/10.1016/j.jchf.2019.12.010.

O’Connor, Christopher M. “Heart Failure Multidisciplinary Teams and New Zealand Rugby: What Can We Learn From the "All Blacks" Rugby Team?” Jacc Heart Fail 8, no. 4 (April 2020): 341–42. https://doi.org/10.1016/j.jchf.2020.02.003.

Pandhi, Paloma, Jozine M. Ter Maaten, Johanna E. Emmens, Joachim Struck, Andreas Bergmann, John G. Cleland, Michael M. Givertz, et al. “Clinical value of pre-discharge bio-adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission.” Eur J Heart Fail 22, no. 4 (April 2020): 683–91. https://doi.org/10.1002/ejhf.1693.

Truby, Lauren K., Christopher O’Connor, Mona Fiuzat, Amanda Stebbins, Adrian Coles, Chetan B. Patel, Bradi Granger, et al. “Sex Differences in Quality of Life and Clinical Outcomes in Patients With Advanced Heart Failure: Insights From the PAL-HF Trial.” Circ Heart Fail 13, no. 4 (April 2020): e006134. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006134.

O’Connor, Christopher M. “The Heart Failure High Five: Medical Therapy and Policy: 2019.” Jacc Heart Fail 8, no. 1 (January 2020): 81–82. https://doi.org/10.1016/j.jchf.2019.11.008.

Psotka, Mitchell A., Gregg C. Fonarow, Larry A. Allen, Karen E. Joynt Maddox, Mona Fiuzat, Paul Heidenreich, Adrian F. Hernandez, Marvin A. Konstam, Clyde W. Yancy, and Christopher M. O’Connor. “The Hospital Readmissions Reduction Program: Nationwide Perspectives and Recommendations: A JACC: Heart Failure Position Paper.” Jacc Heart Fail 8, no. 1 (January 2020): 1–11. https://doi.org/10.1016/j.jchf.2019.07.012.

Tehrani, B. N., A. A. Damluji, M. W. Sherwood, C. Rosner, A. G. Truesdell, K. C. Epps, E. Howard, et al. “Transradial access in acute myocardial infarction complicated by cardiogenic shock: Stratified analysis by shock severity.” Catheterization and Cardiovascular Interventions, January 1, 2020. https://doi.org/10.1002/ccd.29098.

Yang, Siyun, Monique Anderson Starks, Adrian F. Hernandez, Elizabeth L. Turner, Robert M. Califf, Christopher M. O’Connor, Robert J. Mentz, and Kingshuk Roy Choudhury. “Impact of baseline covariate imbalance on bias in treatment effect estimation in cluster randomized trials: Race as an example.” Contemp Clin Trials 88 (January 2020): 105775. https://doi.org/10.1016/j.cct.2019.04.016.

Butler, Javed, Milton Packer, Stephen J. Greene, Mona Fiuzat, Stefan D. Anker, Kevin J. Anstrom, Peter E. Carson, et al. “Heart Failure End Points in Cardiovascular Outcome Trials of Sodium Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Critical Evaluation of Clinical and Regulatory Issues.” Circulation 140, no. 25 (December 17, 2019): 2108–18. https://doi.org/10.1161/CIRCULATIONAHA.119.042155.

Caraballo, César, Nihar R. Desai, Hillary Mulder, Brooke Alhanti, F Perry Wilson, Mona Fiuzat, G Michael Felker, et al. “Clinical Implications of the New York Heart Association Classification.” J Am Heart Assoc 8, no. 23 (December 3, 2019): e014240. https://doi.org/10.1161/JAHA.119.014240.

DeVore, Adam D., Eric Yow, Mitchell W. Krucoff, Matthew W. Sherwood, Linda K. Shaw, Karen Chiswell, Christopher M. O’Connor, Erik Magnus Ohman, and Eric J. Velazquez. “Percutaneous coronary intervention outcomes in patients with stable coronary disease and left ventricular systolic dysfunction.” Esc Heart Fail 6, no. 6 (December 2019): 1233–42. https://doi.org/10.1002/ehf2.12510.

O’Connor, Christopher M. “N-1 and Sequencing Clinical Heart Failure Trials: Charting the Path for Future Clinical Care.” Jacc Heart Fail 7, no. 12 (December 2019): 1089–90. https://doi.org/10.1016/j.jchf.2019.10.006.

Pieske, Burkert, Mahesh J. Patel, Cynthia M. Westerhout, Kevin J. Anstrom, Javed Butler, Justin Ezekowitz, Adrian F. Hernandez, et al. “Baseline features of the VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction) trial.” Eur J Heart Fail 21, no. 12 (December 2019): 1596–1604. https://doi.org/10.1002/ejhf.1664.

Regan, Jessica A., Dalane W. Kitzman, Eric S. Leifer, William E. Kraus, Jerome L. Fleg, Daniel E. Forman, David J. Whellan, et al. “Impact of Age on Comorbidities and Outcomes in Heart Failure With Reduced Ejection Fraction.” Jacc Heart Fail 7, no. 12 (December 2019): 1056–65. https://doi.org/10.1016/j.jchf.2019.09.004.

Beldhuis, Iris E., Koen W. Streng, Peter van der Meer, Jozine M. Ter Maaten, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, et al. “Trajectories of Changes in Renal Function in Patients with Acute Heart Failure.” J Card Fail 25, no. 11 (November 2019): 866–74. https://doi.org/10.1016/j.cardfail.2019.07.004.

Beusekamp, Joost C., Jasper Tromp, John G. F. Cleland, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, John R. Teerlink, et al. “Hyperkalemia and Treatment With RAAS Inhibitors During Acute Heart Failure Hospitalizations and Their Association With Mortality.” Jacc Heart Fail 7, no. 11 (November 2019): 970–79. https://doi.org/10.1016/j.jchf.2019.07.010.

Greene, Stephen J., Adam D. DeVore, Shubin Sheng, Gregg C. Fonarow, Javed Butler, Robert M. Califf, Adrian F. Hernandez, et al. “Representativeness of a Heart Failure Trial by Race and Sex: Results From ASCEND-HF and GWTG-HF.” Jacc Heart Fail 7, no. 11 (November 2019): 980–92. https://doi.org/10.1016/j.jchf.2019.07.011.

O’Connor, Christopher M. “A Call for Change: Level of Statistical Significance.” Jacc Heart Fail 7, no. 11 (November 2019): 993–94. https://doi.org/10.1016/j.jchf.2019.09.005.

Psotka, Mitchell A., Mona Fiuzat, Peter E. Carson, David P. Kao, Jeffrey Cerkvenik, Daniel E. Schaber, Patrick Verta, et al. “Design of a "Lean" Case Report Form for Heart Failure Therapeutic Development.” Jacc Heart Fail 7, no. 11 (November 2019): 913–21. https://doi.org/10.1016/j.jchf.2019.07.001.

Truesdell, Alexander G., Behnam Tehrani, Carolyn Rosner, Ramesh Singh, Shashank Sinha, Mehul Desai, Shashank Desai, et al. “After Action Reviews.” J Invasive Cardiol 31, no. 11 (November 2019): E341.

O’Connor, Christopher M. “Acute Decompensated Heart Failure: Is There a Path Forward?” Jacc Heart Fail 7, no. 10 (October 2019): 911–12. https://doi.org/10.1016/j.jchf.2019.08.005.

Januzzi, James L., Tariq Ahmad, Hillary Mulder, Adrian Coles, Kevin J. Anstrom, Kirkwood F. Adams, Justin A. Ezekowitz, et al. “Natriuretic Peptide Response and Outcomes in Chronic Heart Failure With Reduced Ejection Fraction.” J Am Coll Cardiol 74, no. 9 (September 3, 2019): 1205–17. https://doi.org/10.1016/j.jacc.2019.06.055.

Grodin, Justin L., Max J. Liebo, Javed Butler, Marco Metra, G Michael Felker, Adrian F. Hernandez, Adriaan A. Voors, et al. “Prognostic Implications of Changes in Amino-Terminal Pro-B-Type Natriuretic Peptide in Acute Decompensated Heart Failure: Insights From ASCEND-HF.” J Card Fail 25, no. 9 (September 2019): 703–11. https://doi.org/10.1016/j.cardfail.2019.04.002.

O’Connor, Christopher M. “Heart Failure Physician Burnout: How Can We Help?” Jacc Heart Fail 7, no. 9 (September 2019): 821. https://doi.org/10.1016/j.jchf.2019.07.004.

Felker, G Michael, Maria Borentain, John G. Cleland, Mary M. DeSouza, Paul D. Kessler, Christopher M. O’Connor, Dietmar Seiffert, John R. Teerlink, Adriaan A. Voors, and John J. V. McMurray. “Rationale and design for the development of a novel nitroxyl donor in patients with acute heart failure.” Eur J Heart Fail 21, no. 8 (August 2019): 1022–31. https://doi.org/10.1002/ejhf.1504.

O’Connor, Christopher M. “Why Should We Publish All Clinical Trials?” Jacc Heart Fail 7, no. 8 (August 2019): 730. https://doi.org/10.1016/j.jchf.2019.06.009.

Warraich, Haider J., Christopher M. O’Connor, Hongqiu Yang, Bradi B. Granger, Kimberly S. Johnson, Daniel B. Mark, Kevin J. Anstrom, et al. “African Americans With Advanced Heart Failure Are More Likely to Die in a Health Care Facility Than at Home or in Hospice: An Analysis From the PAL-HF Trial.” J Card Fail 25, no. 8 (August 2019): 693–94. https://doi.org/10.1016/j.cardfail.2019.05.013.

Tehrani, Behnam N., and Christopher M. O’Connor. “Reply: Standardized and Tailored Approach to Therapies for Cardiogenic Shock.” J Am Coll Cardiol 74, no. 4 (July 30, 2019): 593–94. https://doi.org/10.1016/j.jacc.2019.05.039.

O’Connor, Christopher M. “N-of-1 Clinical Trials.” Jacc Heart Fail 7, no. 7 (July 2019): 630–31. https://doi.org/10.1016/j.jchf.2019.05.004.

Ambrosy, Andrew P., Robert J. Mentz, Mona Fiuzat, John G. F. Cleland, Stephen J. Greene, Christopher M. O’Connor, John R. Teerlink, Faiez Zannad, and Scott D. Solomon. “Erratum to 'The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions' [Eur J Heart Fail 2018;20:963-972].” Eur J Heart Fail 21, no. 6 (June 2019): 819. https://doi.org/10.1002/ejhf.1480.

Blumenthal, James A., Yidan Zhu, Gary G. Koch, Patrick J. Smith, Lana L. Watkins, Alan L. Hinderliter, Benson M. Hoffman, et al. “The modifying effects of social support on psychological outcomes in patients with heart failure.” Health Psychol 38, no. 6 (June 2019): 502–8. https://doi.org/10.1037/hea0000716.

O’Connor, Christopher M. “Better Quality of Life Over More Quantity of Life: How We View Time Trade-Off.” Jacc Heart Fail 7, no. 6 (June 2019): 531–32. https://doi.org/10.1016/j.jchf.2019.05.001.

O’Connor, Christopher, Mona Fiuzat, Hillary Mulder, Adrian Coles, Tariq Ahmad, Justin A. Ezekowitz, Kirkwood F. Adams, et al. “Clinical factors related to morbidity and mortality in high-risk heart failure patients: the GUIDE-IT predictive model and risk score.” Eur J Heart Fail 21, no. 6 (June 2019): 770–78. https://doi.org/10.1002/ejhf.1450.

Butler, Javed, Carolyn S. P. Lam, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Burkert Pieske, et al. “Rationale and Design of the VITALITY-HFpEF Trial.” Circ Heart Fail 12, no. 5 (May 2019): e005998. https://doi.org/10.1161/CIRCHEARTFAILURE.119.005998.

O’Connor, Christopher M. “Guideline-Directed Medical Therapy Clinics: A Call to Action for the Heart Failure Team.” Jacc Heart Fail 7, no. 5 (May 2019): 442–43. https://doi.org/10.1016/j.jchf.2019.04.001.

Psotka, Mitchell A., Susan E. Ammon, Mona Fiuzat, Biykem Bozkurt, Eugene S. Chung, Robert T. Cole, Stephen J. Greene, et al. “Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey.” Jacc Heart Fail 7, no. 5 (May 2019): 431–38. https://doi.org/10.1016/j.jchf.2019.02.008.

Russell, Frances M., Robert R. Ehrman, Robinson Ferre, Luna Gargani, Vicki Noble, Jordan Rupp, Sean P. Collins, et al. “Design and rationale of the B-lines lung ultrasound guided emergency department management of acute heart failure (BLUSHED-AHF) pilot trial.” Heart Lung 48, no. 3 (May 2019): 186–92. https://doi.org/10.1016/j.hrtlng.2018.10.027.

Taylor, Rod S., Sarah Walker, Neil A. Smart, Massimo F. Piepoli, Fiona C. Warren, Oriana Ciani, David Whellan, et al. “Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis.” J Am Coll Cardiol 73, no. 12 (April 2, 2019): 1430–43. https://doi.org/10.1016/j.jacc.2018.12.072.

O’Connor, Christopher M. “Heart Failure Fake News: How Do We Distinguish the Truth?” Jacc Heart Fail 7, no. 4 (April 2019): 363. https://doi.org/10.1016/j.jchf.2019.02.004.

Lindenfeld, JoAnn, and Christopher M. O’Connor. “Heart Failure in Women.” Jacc Heart Fail 7, no. 3 (March 2019): 274–75. https://doi.org/10.1016/j.jchf.2019.01.012.

Vaduganathan, Muthiah, Ayman Samman Tahhan, Alaaeddin Alrohaibani, Stephen J. Greene, Gregg C. Fonarow, Orly Vardeny, JoAnn Lindenfeld, et al. “Do Women and Men Respond Similarly to Therapies in Contemporary Heart Failure Clinical Trials?” Jacc Heart Fail 7, no. 3 (March 2019): 267–71. https://doi.org/10.1016/j.jchf.2018.12.016.

Daubert, Melissa A., Kirkwood Adams, Eric Yow, Huiman X. Barnhart, Pamela S. Douglas, Susan Rimmer, Casey Norris, et al. “NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF.” Jacc Heart Fail 7, no. 2 (February 2019): 158–68. https://doi.org/10.1016/j.jchf.2018.10.014.

O’Connor, Christopher M. “Recognizing Heart Failure Awareness Week.” Jacc Heart Fail 7, no. 2 (February 2019): 173. https://doi.org/10.1016/j.jchf.2018.12.013.

Luo, Nancy, Christopher M. O’Connor, Lauren B. Cooper, Jie-Lena Sun, Adrian Coles, Shelby D. Reed, David J. Whellan, Ileana L. Piña, William E. Kraus, and Robert J. Mentz. “Relationship between changing patient-reported outcomes and subsequent clinical events in patients with chronic heart failure: insights from HF-ACTION.” Eur J Heart Fail 21, no. 1 (January 2019): 63–70. https://doi.org/10.1002/ejhf.1299.

O’Connor, Christopher M. “JACC: Heart Failure Peer Review Hall of Fame 2018.” Jacc Heart Fail 7, no. 1 (January 2019): 81. https://doi.org/10.1016/j.jchf.2018.12.001.

Piccini, Jonathan P., Sean D. Pokorney, Kevin J. Anstrom, Olaf Oldenburg, Naresh M. Punjabi, Mona Fiuzat, Gudaye Tasissa, et al. “Adaptive servo-ventilation reduces atrial fibrillation burden in patients with heart failure and sleep apnea.” Heart Rhythm 16, no. 1 (January 2019): 91–97. https://doi.org/10.1016/j.hrthm.2018.07.027.

O’Connor, Christopher M. “Aviation Emergencies for Heart Failure Cardiologists: A New Twist to the Heart Team.” Jacc Heart Fail 6, no. 12 (December 2018): 1047–48. https://doi.org/10.1016/j.jchf.2018.10.018.

Taylor, Rod S., Sarah Walker, Neil A. Smart, Massimo F. Piepoli, Fiona C. Warren, Oriana Ciani, Christopher O’Connor, et al. “Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials.” Eur J Heart Fail 20, no. 12 (December 2018): 1735–43. https://doi.org/10.1002/ejhf.1311.

Mark, Daniel B., Patricia A. Cowper, Kevin J. Anstrom, Shubin Sheng, Melanie R. Daniels, J David Knight, Khaula N. Baloch, et al. “Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure.” J Am Coll Cardiol 72, no. 21 (November 27, 2018): 2551–62. https://doi.org/10.1016/j.jacc.2018.08.2184.

Fudim, Marat, Christopher M. O’Connor, Hillary Mulder, Adrian Coles, Ankeet S. Bhatt, Andrew P. Ambrosy, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Loop diuretic adjustments in patients with chronic heart failure: Insights from HF-ACTION.” Am Heart J 205 (November 2018): 133–41. https://doi.org/10.1016/j.ahj.2018.06.017.

Fudim, Marat, Kishan S. Parikh, Allison Dunning, Adam D. DeVore, Robert J. Mentz, Phillip J. Schulte, Paul W. Armstrong, et al. “Relation of Volume Overload to Clinical Outcomes in Acute Heart Failure (From ASCEND-HF).” Am J Cardiol 122, no. 9 (November 1, 2018): 1506–12. https://doi.org/10.1016/j.amjcard.2018.07.023.

Hamo, Carine E., Christopher O’Connor, Marco Metra, James E. Udelson, Mihai Gheorghiade, and Javed Butler. “A Critical Appraisal of Short-Term End Points in Acute Heart Failure Clinical Trials.” J Card Fail 24, no. 11 (November 2018): 783–92. https://doi.org/10.1016/j.cardfail.2018.08.007.

O’Connor, Christopher M. “COAPTing Heart Failure Physicians, Interventional Cardiologists, and CardioThoracic Surgeons: A New Opportunity for Patients.” Jacc Heart Fail 6, no. 11 (November 2018): 967–68. https://doi.org/10.1016/j.jchf.2018.09.007.

Fudim, Marat, Rahul Loungani, Shannon M. Doerfler, Adrian Coles, Stephen J. Greene, Lauren B. Cooper, Mona Fiuzat, Christopher M. O’Connor, Joseph G. Rogers, and Robert J. Mentz. “Worsening renal function during decongestion among patients hospitalized for heart failure: Findings from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial.” Am Heart J 204 (October 2018): 163–73. https://doi.org/10.1016/j.ahj.2018.07.019.

Greene, Stephen J., Adrian F. Hernandez, Jie-Lena Sun, Javed Butler, Paul W. Armstrong, Justin A. Ezekowitz, Faiez Zannad, et al. “Relationship Between Enrolling Country Income Level and Patient Profile, Protocol Completion, and Trial End Points.” Circulation. Cardiovascular Quality and Outcomes 11, no. 10 (October 2018): e004783. https://doi.org/10.1161/circoutcomes.118.004783.

Jiang, Wei, David J. Whellan, Kirkwood F. Adams, Michael A. Babyak, Stephen H. Boyle, Jennifer L. Wilson, Chetan B. Patel, Joseph G. Rogers, William S. Harris, and Christopher M. O’Connor. “Long-Chain Omega-3 Fatty Acid Supplements in Depressed Heart Failure Patients: Results of the OCEAN Trial.” Jacc Heart Fail 6, no. 10 (October 2018): 833–43. https://doi.org/10.1016/j.jchf.2018.03.011.

O’Connor, Christopher M. “Depression in Heart Failure: Beyond a SADHART.” Jacc Heart Fail 6, no. 10 (October 2018): 885–86. https://doi.org/10.1016/j.jchf.2018.08.004.

Sharma, Abhinav, Lauren B. Cooper, Mona Fiuzat, Robert J. Mentz, João Pedro Ferreira, Javed Butler, David Fitchett, Alan Charles Moses, Christopher O’Connor, and Faiez Zannad. “Antihyperglycemic Therapies to Treat Patients With Heart Failure and Diabetes Mellitus.” Jacc Heart Fail 6, no. 10 (October 2018): 813–22. https://doi.org/10.1016/j.jchf.2018.05.020.

Tahhan, Ayman Samman, Muthiah Vaduganathan, Stephen J. Greene, Gregg C. Fonarow, Mona Fiuzat, Mariell Jessup, JoAnn Lindenfeld, Christopher M. O’Connor, and Javed Butler. “Enrollment of Older Patients, Women, and Racial and Ethnic Minorities in Contemporary Heart Failure Clinical Trials: A Systematic Review.” Jama Cardiol 3, no. 10 (October 1, 2018): 1011–19. https://doi.org/10.1001/jamacardio.2018.2559.

Ambrosy, Andrew P., Hillary Mulder, Adrian Coles, William E. Krauss, Carolyn S. P. Lam, Peter A. McCullough, Ileana Pina, et al. “Renal Function and Exercise Training in AmbulatoryHeart Failure Patients With a Reduced Ejection Fraction.” Am J Cardiol 122, no. 6 (September 15, 2018): 999–1007. https://doi.org/10.1016/j.amjcard.2018.06.011.

Greene, Stephen J., Robert J. Mentz, Mona Fiuzat, Javed Butler, Scott D. Solomon, Andrew P. Ambrosy, Cyrus Mehta, John R. Teerlink, Faiez Zannad, and Christopher M. O’Connor. “Reassessing the Role of Surrogate End Points in Drug Development for Heart Failure.” Circulation 138, no. 10 (September 4, 2018): 1039–53. https://doi.org/10.1161/CIRCULATIONAHA.118.034668.

Cooper, Lauren B., Jonathan Yap, Wan Ting Tay, Tiew-Hwa K. Teng, Michael MacDonald, Inder S. Anand, Abhinav Sharma, et al. “Multi-ethnic comparisons of diabetes in heart failure with reduced ejection fraction: insights from the HF-ACTION trial and the ASIAN-HF registry.” Eur J Heart Fail 20, no. 9 (September 2018): 1281–89. https://doi.org/10.1002/ejhf.1223.

O’Connor, Christopher M. “Politically Correct Heart Failure Research in America to Avoid Geographic Variation.” Jacc Heart Fail 6, no. 9 (September 2018): 805–6. https://doi.org/10.1016/j.jchf.2018.07.010.

Grodin, Justin L., Javed Butler, Marco Metra, G Michael Felker, Adriaan A. Voors, John J. McMurray, Paul W. Armstrong, et al. “Circulating Cardiac Troponin I Levels Measured by a Novel Highly Sensitive Assay in Acute Decompensated Heart Failure: Insights From the ASCEND-HF Trial.” J Card Fail 24, no. 8 (August 2018): 512–19. https://doi.org/10.1016/j.cardfail.2018.06.008.

O’Connor, Christopher M. “HFpEF: From Early Observations to Worldwide Awareness.” Jacc Heart Fail 6, no. 8 (August 2018): 718–19. https://doi.org/10.1016/j.jchf.2018.07.001.

Parikh, Kishan S., Kavita Sharma, Mona Fiuzat, Howard K. Surks, Jyothis T. George, Narimon Honarpour, Christopher Depre, et al. “Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials.” Jacc Heart Fail 6, no. 8 (August 2018): 619–32. https://doi.org/10.1016/j.jchf.2018.06.008.

Parikh, Kishan S., Mona Fiuzat, Gordon Davis, Megan Neely, Penny Blain-Nelson, David J. Whellan, William T. Abraham, et al. “Dose Response of β-Blockers in Adrenergic Receptor Polymorphism Genotypes.” Circ Genom Precis Med 11, no. 8 (August 2018): e002210. https://doi.org/10.1161/CIRCGEN.117.002210.

Vaduganathan, Muthiah, Ravi B. Patel, Robert J. Mentz, Haris Subacius, Neal A. Chatterjee, Stephen J. Greene, Andrew P. Ambrosy, et al. “Sudden Death After Hospitalization for Heart Failure With Reduced Ejection Fraction (from the EVEREST Trial).” Am J Cardiol 122, no. 2 (July 15, 2018): 255–60. https://doi.org/10.1016/j.amjcard.2018.03.362.

Daubert, Melissa A., David J. Whellan, Holger Woehrle, Gudaye Tasissa, Kevin J. Anstrom, JoAnn Lindenfeld, Adam Benjafield, et al. “Treatment of sleep-disordered breathing in heart failure impacts cardiac remodeling: Insights from the CAT-HF Trial.” Am Heart J 201 (July 2018): 40–48. https://doi.org/10.1016/j.ahj.2018.03.026.

O’Connor, Christopher M. “Cardiovascular Drug Pricing: Less Innovation for More Access?” Jacc Heart Fail 6, no. 7 (July 2018): 613–14. https://doi.org/10.1016/j.jchf.2018.05.016.

Warraich, Haider J., Christopher O’Connor, Angie Wu, Adrian Coles, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Differences Between Patients Enrolled Early and Late During Clinical Trial Recruitment: Insights From the HF-ACTION Trial.” Circ Cardiovasc Qual Outcomes 11, no. 7 (July 2018): e004643. https://doi.org/10.1161/CIRCOUTCOMES.117.004643.

Ambrosy, Andrew P., Robert J. Mentz, Mona Fiuzat, John G. F. Cleland, Stephen J. Greene, Christopher M. O’Connor, John R. Teerlink, Faiez Zannad, and Scott D. Solomon. “The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions.” Eur J Heart Fail 20, no. 6 (June 2018): 963–72. https://doi.org/10.1002/ejhf.1159.

O’Connor, Christopher M. “Dying With Dignity and Heart Failure: A Lesson From Barbara Bush.” Jacc Heart Fail 6, no. 6 (June 2018): 536–37. https://doi.org/10.1016/j.jchf.2018.04.011.

Ahmad, Tariq, Keyanna Jackson, Veena S. Rao, WH Wilson Tang, Meredith A. Brisco-Bacik, Horng H. Chen, G Michael Felker, et al. “Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury.” Circulation 137, no. 19 (May 8, 2018): 2016–28. https://doi.org/10.1161/CIRCULATIONAHA.117.030112.

Ambrosy, Andrew P., Ankeet S. Bhatt, Amanda L. Stebbins, Lisa M. Wruck, Marat Fudim, Stephen J. Greene, William E. Kraus, et al. “Prevalent digoxin use and subsequent risk of death or hospitalization in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) randomized controlled trial.” Am Heart J 199 (May 2018): 97–104. https://doi.org/10.1016/j.ahj.2018.02.004.

Metra, Marco, Gad Cotter, Stefanie Senger, Christopher Edwards, John G. Cleland, Piotr Ponikowski, Guillermo C. Cursack, et al. “Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data.” Circ Heart Fail 11, no. 5 (May 2018): e004644. https://doi.org/10.1161/CIRCHEARTFAILURE.117.004644.

O’Connor, Christopher M. “What's One More Day?” Jacc Heart Fail 6, no. 5 (May 2018): 438. https://doi.org/10.1016/j.jchf.2018.03.015.

Rubio-Gracia, Jorge, Biniyam G. Demissei, Jozine M. Ter Maaten, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, et al. “Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure.” Int J Cardiol 258 (May 1, 2018): 185–91. https://doi.org/10.1016/j.ijcard.2018.01.067.

Ahmad, Tariq, Lars H. Lund, Pooja Rao, Rohit Ghosh, Prashant Warier, Benjamin Vaccaro, Ulf Dahlström, Christopher M. O’Connor, G Michael Felker, and Nihar R. Desai. “Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients.” J Am Heart Assoc 7, no. 8 (April 12, 2018). https://doi.org/10.1161/JAHA.117.008081.

Cerbin, Lukasz P., Andrew P. Ambrosy, Stephen J. Greene, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, et al. “Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial.” Jacc Heart Fail 6, no. 4 (April 2018): 298–307. https://doi.org/10.1016/j.jchf.2018.01.018.

O’Connor, Christopher M., and Michael R. Bristow. “Changing the Research Culture in the United States.” Jacc Heart Fail 6, no. 4 (April 2018): 344–45. https://doi.org/10.1016/j.jchf.2018.03.001.

Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.” J Am Coll Cardiol 71, no. 9 (March 6, 2018): 1021–34. https://doi.org/10.1016/j.jacc.2017.12.048.

O’Connor, Christopher M. “Heart Failure Health Care 2018: Challenges and Opportunities.” Jacc Heart Fail 6, no. 3 (March 2018): 262–63. https://doi.org/10.1016/j.jchf.2018.01.013.

Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.” Circulation 137, no. 9 (February 27, 2018): 961–72. https://doi.org/10.1161/CIRCULATIONAHA.117.033502.

Bhatt, Ankeet S., Lauren B. Cooper, Andrew P. Ambrosy, Robert M. Clare, Adrian Coles, Emer Joyce, Arun Krishnamoorthy, et al. “Interaction of Body Mass Index on the Association Between N-Terminal-Pro-b-Type Natriuretic Peptide and Morbidity and Mortality in Patients With Acute Heart Failure: Findings From ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” J Am Heart Assoc 7, no. 3 (February 3, 2018). https://doi.org/10.1161/JAHA.117.006740.

Armstrong, Paul W., Lothar Roessig, Mahesh J. Patel, Kevin J. Anstrom, Javed Butler, Adriaan A. Voors, Carolyn S. P. Lam, et al. “A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Efficacy and Safety of the Oral Soluble Guanylate Cyclase Stimulator: The VICTORIA Trial.” Jacc Heart Fail 6, no. 2 (February 2018): 96–104. https://doi.org/10.1016/j.jchf.2017.08.013.

Cotter, Gad, Marco Metra, Beth A. Davison, Guillaume Jondeau, John G. F. Cleland, Robert C. Bourge, Olga Milo, et al. “Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe?” Eur J Heart Fail 20, no. 2 (February 2018): 317–22. https://doi.org/10.1002/ejhf.889.

Fudim, Marat, Christopher M. O’Connor, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Adrian Coles, Justin A. Ezekowitz, et al. “Aetiology, timing and clinical predictors of early vs. late readmission following index hospitalization for acute heart failure: insights from ASCEND-HF.” Eur J Heart Fail 20, no. 2 (February 2018): 304–14. https://doi.org/10.1002/ejhf.1020.

O’Connor, Christopher M. “Smartphone, Mom, and HFpEF.” Jacc Heart Fail 6, no. 2 (February 2018): 176. https://doi.org/10.1016/j.jchf.2017.12.010.

O’Connor, Christopher M., Mitchell A. Psotka, Mona Fiuzat, JoAnn Lindenfeld, William T. Abraham, Michael R. Bristow, Daniel Canos, et al. “Improving Heart Failure Therapeutics Development in the United States: The Heart Failure Collaboratory.” J Am Coll Cardiol 71, no. 4 (January 30, 2018): 443–53. https://doi.org/10.1016/j.jacc.2017.11.048.

O’Connor, Christopher M. “I Don't Care How Low My BNP Is, I Want to Feel Good.” Jacc Heart Fail 6, no. 1 (January 2018): 82–83. https://doi.org/10.1016/j.jchf.2017.11.004.

Pastva, Amy M., Pamela W. Duncan, Gordon R. Reeves, M Benjamin Nelson, David J. Whellan, Christopher M. O’Connor, Joel D. Eggebeen, et al. “Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial.” Contemp Clin Trials 64 (January 2018): 118–27. https://doi.org/10.1016/j.cct.2017.10.014.

Daubert, Melissa A., Eric Yow, Gary Dunn, Sotir Marchev, Huiman Barnhart, Pamela S. Douglas, Christopher O’Connor, Sidney Goldstein, James E. Udelson, and Hani N. Sabbah. “Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide.” Circ Heart Fail 10, no. 12 (December 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.117.004389.

Alenezi, Fawaz, Beverly H. Brummett, Stephen H. Boyle, Zainab Samad, Michael A. Babyak, Nabil Alzaeim, Jennifer Wilson, et al. “Usefulness of Myocardial Annular Velocity Change During Mental Stress to Predict Cardiovascular Outcome in Patients With Coronary Artery Disease (From the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment Trial).” Am J Cardiol 120, no. 9 (November 1, 2017): 1495–1500. https://doi.org/10.1016/j.amjcard.2017.07.039.

O’Connor, Christopher M. “Goodbye Mihai: We Will Miss You.” Jacc Heart Fail 5, no. 11 (November 2017): 848–49. https://doi.org/10.1016/j.jchf.2017.09.007.

O’Connor, Christopher M. “Q&A With the JACC: Heart Failure Editor-in-Chief: Marking the 5-Year Milestone.” Jacc Heart Fail 5, no. 10 (October 2017): 758–59. https://doi.org/10.1016/j.jchf.2017.08.006.

Sharma, Abhinav, Biniyam G. Demissei, Jasper Tromp, Hans L. Hillege, John G. Cleland, Christopher M. O’Connor, Marco Metra, et al. “A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure.” Eur J Heart Fail 19, no. 10 (October 2017): 1310–20. https://doi.org/10.1002/ejhf.912.

Sharma, Abhinav, Susanna R. Stevens, Joseph Lucas, Mona Fiuzat, Kirkwood F. Adams, David J. Whellan, Mark P. Donahue, et al. “Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study.” Jacc Heart Fail 5, no. 10 (October 2017): 724–34. https://doi.org/10.1016/j.jchf.2017.07.013.

Luo, Nancy, Tiew-Hwa Katherine Teng, Wan Ting Tay, Inder S. Anand, William E. Kraus, Houng Bang Liew, Lieng Hsi Ling, et al. “Multinational and multiethnic variations in health-related quality of life in patients with chronic heart failure.” Am Heart J 191 (September 2017): 75–81. https://doi.org/10.1016/j.ahj.2017.06.016.

O’Connor, Christopher M. “America and Apple Pie: How Do We Change the American Health Care System?” Jacc Heart Fail 5, no. 9 (September 2017): 686–87. https://doi.org/10.1016/j.jchf.2017.07.006.

Sherwood, Andrew, LaBarron K. Hill, James A. Blumenthal, Kirkwood F. Adams, Nicola J. Paine, Gary G. Koch, Christopher M. O’Connor, Kristy S. Johnson, and Alan L. Hinderliter. “Blood pressure reactivity to psychological stress is associated with clinical outcomes in patients with heart failure.” Am Heart J 191 (September 2017): 82–90. https://doi.org/10.1016/j.ahj.2017.07.003.

O’Connor, Christopher M. “Does Institutional Memory Matter?” Jacc Heart Fail 5, no. 8 (August 2017): 616. https://doi.org/10.1016/j.jchf.2017.07.001.

Rogers, Joseph G., Chetan B. Patel, Robert J. Mentz, Bradi B. Granger, Karen E. Steinhauser, Mona Fiuzat, Patricia A. Adams, et al. “Palliative Care in Heart Failure: The PAL-HF Randomized, Controlled Clinical Trial.” J Am Coll Cardiol 70, no. 3 (July 18, 2017): 331–41. https://doi.org/10.1016/j.jacc.2017.05.030.

O’Connor, Christopher M. “A Decade With Editorial Mentors: The Day They Dropped the Mic.” Jacc Heart Fail 5, no. 7 (July 2017): 541–42. https://doi.org/10.1016/j.jchf.2017.05.009.

Tromp, Jasper, Mohsin A. F. Khan, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Biomarker Profiles of Acute Heart Failure Patients With a Mid-Range Ejection Fraction.” Jacc Heart Fail 5, no. 7 (July 2017): 507–17. https://doi.org/10.1016/j.jchf.2017.04.007.

Greene, Stephen J., Adrian F. Hernandez, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Javed Butler, Lukasz P. Cerbin, et al. “Hospitalization for Recently Diagnosed Versus Worsening Chronic Heart Failure: From the ASCEND-HF Trial.” J Am Coll Cardiol 69, no. 25 (June 27, 2017): 3029–39. https://doi.org/10.1016/j.jacc.2017.04.043.

Banks, Adam, Samuel Broderick, Karen Chiswell, Linda Shaw, Adam Devore, Mona Fiuzat, Christopher O’Connor, Gary Michael Felker, Eric Velazquez, and Robert Mentz. “Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease).” Am J Cardiol 119, no. 11 (June 1, 2017): 1703–9. https://doi.org/10.1016/j.amjcard.2017.02.053.

Cleland, John G. F., John R. Teerlink, Beth A. Davison, Ahmad Shoaib, Marco Metra, Stefanie Senger, Olga Milo, et al. “Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS).” Eur J Heart Fail 19, no. 6 (June 2017): 739–47. https://doi.org/10.1002/ejhf.786.

Demissei, Biniyam G., Douwe Postmus, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “Plasma biomarkers to predict or rule out early post-discharge events after hospitalization for acute heart failure.” Eur J Heart Fail 19, no. 6 (June 2017): 728–38. https://doi.org/10.1002/ejhf.766.

O’Connor, Christopher M. “Development of Acute Decompensated Heart Failure Therapies: Is the Journey Over?” Jacc Heart Fail 5, no. 6 (June 2017): 464–65. https://doi.org/10.1016/j.jchf.2017.04.010.

Raslan, Ismail R., Paul Brown, Cynthia M. Westerhout, Justin A. Ezekowitz, Adrian F. Hernandez, Randall C. Starling, Christopher O’Connor, et al. “Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score.” Am Heart J 188 (June 2017): 127–35. https://doi.org/10.1016/j.ahj.2017.03.014.

Packer, Milton, Christopher O’Connor, John J. V. McMurray, Janet Wittes, William T. Abraham, Stefan D. Anker, Kenneth Dickstein, et al. “Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure.” N Engl J Med 376, no. 20 (May 18, 2017): 1956–64. https://doi.org/10.1056/NEJMoa1601895.

O’Connor, Christopher M. “High Heart Failure Readmission Rates: Is It the Health System's Fault?” Jacc Heart Fail 5, no. 5 (May 2017): 393. https://doi.org/10.1016/j.jchf.2017.03.011.

Packer, Milton, Richard Holcomb, William T. Abraham, Stefan Anker, Kenneth Dickstein, Gerasimos Filippatos, Henry Krum, et al. “Rationale for and design of the TRUE-AHF trial: the effects of ularitide on the short-term clinical course and long-term mortality of patients with acute heart failure.” Eur J Heart Fail 19, no. 5 (May 2017): 673–81. https://doi.org/10.1002/ejhf.698.

Reeves, Gordon R., David J. Whellan, Christopher M. O’Connor, Pamela Duncan, Joel D. Eggebeen, Timothy M. Morgan, Leigh Ann Hewston, Amy Pastva, Mahesh J. Patel, and Dalane W. Kitzman. “A Novel Rehabilitation Intervention for Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Pilot Study.” Jacc Heart Fail 5, no. 5 (May 2017): 359–66. https://doi.org/10.1016/j.jchf.2016.12.019.

Luo, Nancy, Peter Merrill, Kishan S. Parikh, David J. Whellan, Ileana L. Piña, Mona Fiuzat, William E. Kraus, et al. “Exercise Training in Patients With Chronic Heart Failure and Atrial Fibrillation.” J Am Coll Cardiol 69, no. 13 (April 4, 2017): 1683–91. https://doi.org/10.1016/j.jacc.2017.01.032.

Ambrosy, Andrew P., Lukasz P. Cerbin, Adam D. DeVore, Stephen J. Greene, William E. Kraus, Christopher M. O’Connor, Ileana L. Piña, et al. “Aerobic exercise training and general health status in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)trial.” Am Heart J 186 (April 2017): 130–38. https://doi.org/10.1016/j.ahj.2016.12.017.

Butler, Javed, Carine E. Hamo, James E. Udelson, Christopher O’Connor, Hani N. Sabbah, Marco Metra, Sanjiv J. Shah, et al. “Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations.” Circ Heart Fail 10, no. 4 (April 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003800.

O’Connor, Christopher M., and Dirk J. van Veldhuisen. “Data Sharing From the Editors' Perspective: Our Hope With Limitations.” Jacc Heart Fail 5, no. 4 (April 2017): 314–15. https://doi.org/10.1016/j.jchf.2017.02.007.

Sun, Julia L., Stephen H. Boyle, Zainab Samad, Michael A. Babyak, Jennifer L. Wilson, Cynthia Kuhn, Richard C. Becker, et al. “Mental stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients.” Eur J Prev Cardiol 24, no. 6 (April 2017): 591–99. https://doi.org/10.1177/2047487316686435.

O’Connor, Christopher M., David J. Whellan, Mona Fiuzat, Naresh M. Punjabi, Gudaye Tasissa, Kevin J. Anstrom, Adam V. Benjafield, et al. “Cardiovascular Outcomes With Minute Ventilation-Targeted Adaptive Servo-Ventilation Therapy in Heart Failure: The CAT-HF Trial.” J Am Coll Cardiol 69, no. 12 (March 28, 2017): 1577–87. https://doi.org/10.1016/j.jacc.2017.01.041.

Felker, G Michael, Robert J. Mentz, Robert T. Cole, Kirkwood F. Adams, Gregory F. Egnaczyk, Mona Fiuzat, Chetan B. Patel, et al. “Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure.” J Am Coll Cardiol 69, no. 11 (March 21, 2017): 1399–1406. https://doi.org/10.1016/j.jacc.2016.09.004.

Levy, Wayne C., Yanhong Li, Shelby D. Reed, Michael R. Zile, Ramin Shadman, Todd Dardas, David J. Whellan, et al. “Does the Implantable Cardioverter-Defibrillator Benefit Vary With the Estimated Proportional Risk of Sudden Death in Heart Failure Patients?” Jacc Clin Electrophysiol 3, no. 3 (March 2017): 291–98. https://doi.org/10.1016/j.jacep.2016.09.006.

Matsue, Yuya, Jozine M. Ter Maaten, Joachim Struck, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure.” J Card Fail 23, no. 3 (March 2017): 231–39. https://doi.org/10.1016/j.cardfail.2016.09.007.

Matsue, Yuya, Peter van der Meer, Kevin Damman, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Blood urea nitrogen-to-creatinine ratio in the general population and in patients with acute heart failure.” Heart 103, no. 6 (March 2017): 407–13. https://doi.org/10.1136/heartjnl-2016-310112.

O’Connor, Christopher M. “Is Salt Bad for You?” Jacc Heart Fail 5, no. 3 (March 2017): 238–39. https://doi.org/10.1016/j.jchf.2017.01.003.

Reeves, Gordon R., David J. Whellan, Pamela Duncan, Christopher M. O’Connor, Amy M. Pastva, Joel D. Eggebeen, Leigh Ann Hewston, et al. “Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale.” Am Heart J 185 (March 2017): 130–39. https://doi.org/10.1016/j.ahj.2016.12.012.

Feigal, Jacob P., Stephen H. Boyle, Zainab Samad, Eric J. Velazquez, Jennifer L. Wilson, Richard C. Becker, Redford B. Williams, et al. “Associations between positive emotional well-being and stress-induced myocardial ischemia: Well-being scores predict exercise-induced ischemia.” J Psychosom Res 93 (February 2017): 14–18. https://doi.org/10.1016/j.jpsychores.2016.11.012.

Kitai, Takeshi, Justin L. Grodin, Robert J. Mentz, Adrian F. Hernandez, Javed Butler, Marco Metra, John J. McMurray, et al. “Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial.” Eur J Heart Fail 19, no. 2 (February 2017): 241–49. https://doi.org/10.1002/ejhf.629.

O’Connor, Christopher M. “21st Century Cures: A Step Forward for Patients With Heart Failure.” Jacc Heart Fail 5, no. 2 (February 2017): 154. https://doi.org/10.1016/j.jchf.2016.12.004.

Tromp, Jasper, Jozine M. Ter Maaten, Kevin Damman, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials).” Am J Cardiol 119, no. 2 (January 15, 2017): 290–96. https://doi.org/10.1016/j.amjcard.2016.09.038.

Ambrosy, Andrew P., Lukasz P. Cerbin, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, Mark E. Dunlap, et al. “Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From the ASCEND-HF Trial.” Jacc Heart Fail 5, no. 1 (January 2017): 1–13. https://doi.org/10.1016/j.jchf.2016.09.012.

Navarese, Eliano P., Paul A. Gurbel, Felicita Andreotti, Michalina Marta Kołodziejczak, Suetonia C. Palmer, Sofia Dias, Antonino Buffon, et al. “Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis.” Plos One 12, no. 2 (2017): e0168726. https://doi.org/10.1371/journal.pone.0168726.

O’Connor, C. “HFSA President's Paper (Accepted).” Journal of Cardiac Failure, January 1, 2017. https://doi.org/10.1016/j.cardfail.2017.07.399.

O’Connor, Christopher M. “Developing Breakthrough Drugs for Heart Failure: Lessons Learned From the Cystic Fibrosis Experience.” Jacc Heart Fail 5, no. 1 (January 2017): 71–72. https://doi.org/10.1016/j.jchf.2016.11.008.

Sherwood, Andrew, James A. Blumenthal, Gary G. Koch, Benson M. Hoffman, Lana L. Watkins, Patrick J. Smith, Christopher M. O’Connor, et al. “Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial.” Circ Heart Fail 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003410.

Streng, Koen W., Jozine M. Ter Maaten, John G. Cleland, Christopher M. O’Connor, Beth A. Davison, Marco Metra, Michael M. Givertz, et al. “Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure.” Circ Heart Fail 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003350.

Verma, Amanda K., Phillip J. Schulte, Vera Bittner, Steven J. Keteyian, Jerome L. Fleg, Ileana L. Piña, Ann M. Swank, et al. “Socioeconomic and partner status in chronic heart failure: Relationship to exercise capacity, quality of life, and clinical outcomes.” Am Heart J 183 (January 2017): 54–61. https://doi.org/10.1016/j.ahj.2016.10.007.

O’Connor, Christopher M. “Not Your Mother's FDA.” Jacc Heart Fail 4, no. 12 (December 2016): 978. https://doi.org/10.1016/j.jchf.2016.10.001.

Vegter, Eline L., Daniela Schmitter, Yanick Hagemeijer, Ekaterina S. Ovchinnikova, Pim van der Harst, John R. Teerlink, Christopher M. O’Connor, et al. “Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure.” Int J Cardiol 224 (December 1, 2016): 231–39. https://doi.org/10.1016/j.ijcard.2016.09.010.

Demissei, Biniyam G., Douwe Postmus, Licette C. Y. Liu, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, et al. “Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial.” Int J Cardiol 223 (November 15, 2016): 967–75. https://doi.org/10.1016/j.ijcard.2016.08.271.

O’Connor, Christopher M. “Peer Review of Peer Review: Somewhere Over the Rainbow.” Jacc Heart Fail 4, no. 11 (November 2016): 907–8. https://doi.org/10.1016/j.jchf.2016.09.005.

Parikh, Kishan S., Adrian Coles, Phillip J. Schulte, William E. Kraus, Jerome L. Fleg, Steven J. Keteyian, Ileana L. Piña, et al. “Relation of Angina Pectoris to Outcomes, Quality of Life, and Response to Exercise Training in Patients With Chronic Heart Failure (from HF-ACTION).” Am J Cardiol 118, no. 8 (October 15, 2016): 1211–16. https://doi.org/10.1016/j.amjcard.2016.07.040.

Tromp, Jasper, Sven Meyer, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Acute heart failure in the young: Clinical characteristics and biomarker profiles.” Int J Cardiol 221 (October 15, 2016): 1067–72. https://doi.org/10.1016/j.ijcard.2016.06.339.

Cotter, Gad, Beth A. Davison, Olga Milo, Robert C. Bourge, John G. F. Cleland, Guillaume Jondeau, Henry Krum, et al. “Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.” J Card Fail 22, no. 10 (October 2016): 815–22. https://doi.org/10.1016/j.cardfail.2015.12.017.

O’Connor, Christopher M. “The International Olympic Games: Heart Teams and Heart Failure.” Jacc Heart Fail 4, no. 10 (October 2016): 826–27. https://doi.org/10.1016/j.jchf.2016.08.004.

Greene, Stephen J., Adrian F. Hernandez, Jie-Lena Sun, Marco Metra, Javed Butler, Andrew P. Ambrosy, Justin A. Ezekowitz, et al. “Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Circ Heart Fail 9, no. 9 (September 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.002986.

Luo, Nancy, Joseph G. Rogers, Gwen C. Dodson, Chetan B. Patel, Anthony N. Galanos, Carmelo A. Milano, Christopher M. O’Connor, and Robert J. Mentz. “Usefulness of Palliative Care to Complement the Management of Patients on Left Ventricular Assist Devices.” Am J Cardiol 118, no. 5 (September 1, 2016): 733–38. https://doi.org/10.1016/j.amjcard.2016.06.010.

O’Connor, Christopher M. “The Mentor's Mentor: The Life of Galen Wagner.” Jacc Heart Fail 4, no. 9 (September 2016): 759. https://doi.org/10.1016/j.jchf.2016.07.009.

Davison, Beth A., Marco Metra, Stefanie Senger, Christopher Edwards, Olga Milo, Daniel M. Bloomfield, John G. Cleland, et al. “Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality.” Eur J Heart Fail 18, no. 8 (August 2016): 1041–50. https://doi.org/10.1002/ejhf.540.

Kelly, Jacob P., Allison Dunning, Phillip J. Schulte, Mona Fiuzat, Eric S. Leifer, Jerome L. Fleg, Lawton S. Cooper, et al. “Statins and Exercise Training Response in Heart Failure Patients: Insights From HF-ACTION.” Jacc Heart Fail 4, no. 8 (August 2016): 617–24. https://doi.org/10.1016/j.jchf.2016.05.006.

Kelly, Jacob P., Lauren B. Cooper, Dianne Gallup, Kevin J. Anstrom, Horng H. Chen, Margaret M. Redfield, Christopher M. O’Connor, Robert J. Mentz, Adrian F. Hernanadez, and G Michael Felker. “Implications of Using Different Definitions on Outcomes in Worsening Heart Failure.” Circ Heart Fail 9, no. 8 (August 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003048.

O’Connor, Christopher M. “Can Academic Cardiology Divisions Survive?” Jacc Heart Fail 4, no. 8 (August 2016): 687–88. https://doi.org/10.1016/j.jchf.2016.06.001.

Paine, Nicola J., Alan L. Hinderliter, James A. Blumenthal, Kirkwood F. Adams, Carla A. Sueta, Patricia P. Chang, Christopher M. O’Connor, and Andrew Sherwood. “Reactive hyperemia is associated with adverse clinical outcomes in heart failure.” Am Heart J 178 (August 2016): 108–14. https://doi.org/10.1016/j.ahj.2016.05.008.

Ter Maaten, Jozine M., Kevin Damman, Jennifer S. Hanberg, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, John R. Teerlink, et al. “Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure.” Circ Heart Fail 9, no. 8 (August 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003109.

Banks, Adam Z., Robert J. Mentz, Amanda Stebbins, Catherine R. Mikus, Phillip J. Schulte, Jerome L. Fleg, Lawton S. Cooper, et al. “Response to Exercise Training and Outcomes in Patients With Heart Failure and Diabetes Mellitus: Insights From the HF-ACTION Trial.” J Card Fail 22, no. 7 (July 2016): 485–91. https://doi.org/10.1016/j.cardfail.2015.12.007.

Biegus, Jan, Hans L. Hillege, Douwe Postmus, Mattia A. E. Valente, Daniel M. Bloomfield, John G. F. Cleland, Gad Cotter, et al. “Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study.” Eur J Heart Fail 18, no. 7 (July 2016): 830–39. https://doi.org/10.1002/ejhf.532.

Denardo, Scott J., David M. Vock, Carsten M. Schmalfuss, Gregory D. Young, James E. Tcheng, and Christopher M. O’Connor. “Baseline Hemodynamics and Response to Contrast Media During Diagnostic Cardiac Catheterization Predict Adverse Events in Heart Failure Patients.” Circ Heart Fail 9, no. 7 (July 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002529.

O’Connor, Christopher M. “The Year in Heart Failure Review 2015 to 2016.” Jacc Heart Fail 4, no. 7 (July 2016): 603–4. https://doi.org/10.1016/j.jchf.2016.05.005.

Reeves, Gordon R., David J. Whellan, Mahesh J. Patel, Christopher M. O’Connor, Pamela Duncan, Joel D. Eggebeen, Timothy M. Morgan, Leigh A. Hewston, Amy M. Pastva, and Dalane W. Kitzman. “Comparison of Frequency of Frailty and Severely Impaired Physical Function in Patients ≥60 Years Hospitalized With Acute Decompensated Heart Failure Versus Chronic Stable Heart Failure With Reduced and Preserved Left Ventricular Ejection Fraction.” Am J Cardiol 117, no. 12 (June 15, 2016): 1953–58. https://doi.org/10.1016/j.amjcard.2016.03.046.

Emmens, Johanna E., Jozine M. Ter Maaten, Yuya Matsue, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome.” Eur J Heart Fail 18, no. 6 (June 2016): 641–49. https://doi.org/10.1002/ejhf.426.

Metra, Marco, Robert J. Mentz, Adrian F. Hernandez, Gretchen M. Heizer, Paul W. Armstrong, Nadine Clausell, Ramon Corbalan, et al. “Geographic Differences in Patients in a Global Acute Heart Failure Clinical Trial (from the ASCEND-HF Trial).” Am J Cardiol 117, no. 11 (June 1, 2016): 1771–78. https://doi.org/10.1016/j.amjcard.2016.03.002.

O’Connor, Christopher M. “Social Media: Can It Reduce Heart Failure Events?” Jacc Heart Fail 4, no. 6 (June 2016): 514–15. https://doi.org/10.1016/j.jchf.2016.04.006.

Ter Maaten, Jozine M., Mattia A. E. Valente, Kevin Damman, John G. Cleland, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, et al. “Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure.” Circ Heart Fail 9, no. 6 (June 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002845.

Whellan, David J., Amanda Stebbins, Adrian F. Hernandez, Justin A. Ezekowitz, John J. V. McMurray, Paul J. Mather, Vic Hasselblad, and Christopher M. O’Connor. “Dichotomous Relationship Between Age and 30-Day Death or Rehospitalization in Heart Failure Patients Admitted With Acute Decompensated Heart Failure: Results From the ASCEND-HF Trial.” J Card Fail 22, no. 6 (June 2016): 409–16. https://doi.org/10.1016/j.cardfail.2016.02.011.

Wong, Yee Weng, Robert J. Mentz, G Michael Felker, Justin Ezekowitz, Karen Pieper, Gretchen Heizer, Vic Hasselblad, et al. “Nesiritide in patients hospitalized for acute heart failure: does timing matter? Implication for future acute heart failure trials.” Eur J Heart Fail 18, no. 6 (June 2016): 684–92. https://doi.org/10.1002/ejhf.487.

Navarese, Eliano P., Michalina Kolodziejczak, Dean J. Kereiakes, Udaya S. Tantry, Christopher O’Connor, and Paul A. Gurbel. “Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review.” Ann Intern Med 164, no. 9 (May 3, 2016): 600–607. https://doi.org/10.7326/M15-2994.

O’Connor, Christopher M., Mona Fiuzat, and JoAnn Lindenfeld. “Are We Really in Love With Old Therapies?” Jacc Heart Fail, April 12, 2016. https://doi.org/10.1016/j.jchf.2016.02.011.

Garber, Adam M., Robert J. Mentz, Hussein R. Al-Khalidi, Linda K. Shaw, Mona Fiuzat, Christopher M. O’Connor, and Eric J. Velazquez. “Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction.” J Thromb Thrombolysis 41, no. 3 (April 2016): 365–73. https://doi.org/10.1007/s11239-015-1252-0.

Ovchinnikova, Ekaterina S., Daniela Schmitter, Eline L. Vegter, Jozine M. Ter Maaten, Mattia A. E. Valente, Licette C. Y. Liu, Pim van der Harst, et al. “Signature of circulating microRNAs in patients with acute heart failure.” Eur J Heart Fail 18, no. 4 (April 2016): 414–23. https://doi.org/10.1002/ejhf.332.

O’Connor, Christopher M. “Why Negative Trials Are Positive for Heart Failure Patients.” Jacc Heart Fail 4, no. 4 (April 2016): 329–30. https://doi.org/10.1016/j.jchf.2016.02.010.

Rosendorff, Clive, and Clive Writing Committee. “Treatment of Hypertension in Patients with Coronary Artery Disease. A Case-Based Summary of the 2015 AHA/ACC/ASH Scientific Statement.” Am J Med 129, no. 4 (April 2016): 372–78. https://doi.org/10.1016/j.amjmed.2015.10.045.

Samsky, Marc D., Allison Dunning, Adam D. DeVore, Phillip J. Schulte, Randall C. Starling, WH Wilson Tang, Paul W. Armstrong, et al. “Liver function tests in patients with acute heart failure and associated outcomes: insights from ASCEND-HF.” Eur J Heart Fail 18, no. 4 (April 2016): 424–32. https://doi.org/10.1002/ejhf.440.

Ezekowitz, Justin A., Mohua Podder, Adrian F. Hernandez, Paul W. Armstrong, Randall C. Starling, Christopher M. O’Connor, and Robert M. Califf. “Arrival by ambulance in acute heart failure: insights into the mode of presentation from Acute Studies of Nesiritide in Decompensated Heart Failure (ASCEND-HF).” Bmj Open 6, no. 3 (March 17, 2016): e010201. https://doi.org/10.1136/bmjopen-2015-010201.

Ambrosy, Andrew P., Adrian F. Hernandez, Paul W. Armstrong, Javed Butler, Allison Dunning, Justin A. Ezekowitz, G Michael Felker, et al. “The clinical course of health status and association with outcomes in patients hospitalized for heart failure: insights from ASCEND-HF.” Eur J Heart Fail 18, no. 3 (March 2016): 306–13. https://doi.org/10.1002/ejhf.420.

Cooper, Lauren B., Robert J. Mentz, Susanna R. Stevens, G Michael Felker, Carlo Lombardi, Marco Metra, Lynne W. Stevenson, et al. “Hemodynamic Predictors of Heart Failure Morbidity and Mortality: Fluid or Flow?” J Card Fail 22, no. 3 (March 2016): 182–89. https://doi.org/10.1016/j.cardfail.2015.11.012.

Demissei, Biniyam G., Mattia A. E. Valente, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “Optimizing clinical use of biomarkers in high-risk acute heart failure patients.” Eur J Heart Fail 18, no. 3 (March 2016): 269–80. https://doi.org/10.1002/ejhf.443.

Fiuzat, Mona, Olaf Oldenberg, David J. Whellan, Holger Woehrle, Naresh M. Punjabi, Kevin J. Anstrom, Amy B. Blase, Adam V. Benjafield, JoAnn Lindenfeld, and Christopher M. O’Connor. “Lessons learned from a clinical trial: Design, rationale, and insights from The Cardiovascular Improvements with Minute Ventilation-targeted Adaptive Sero-Ventilation (ASV) Therapy in Heart Failure (CAT-HF) Study.” Contemp Clin Trials 47 (March 2016): 158–64. https://doi.org/10.1016/j.cct.2016.01.001.

O’Connor, Christopher M. “I Lost a Friend From HFpEF: William Anlyan, MD, Chancellor Emeritus and Duke University Trustee.” Jacc Heart Fail 4, no. 3 (March 2016): 230–31. https://doi.org/10.1016/j.jchf.2016.01.007.

Perez, Antonio L., Justin L. Grodin, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, G Michael Felker, et al. “Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy.” Eur J Heart Fail 18, no. 3 (March 2016): 290–97. https://doi.org/10.1002/ejhf.456.

Keteyian, Steven J., Mahesh Patel, William E. Kraus, Clinton A. Brawner, Timothy R. McConnell, Ileana L. Piña, Eric S. Leifer, et al. “Variables Measured During Cardiopulmonary Exercise Testing as Predictors of Mortality in Chronic Systolic Heart Failure.” J Am Coll Cardiol 67, no. 7 (February 23, 2016): 780–89. https://doi.org/10.1016/j.jacc.2015.11.050.

Demissei, Biniyam G., John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, Beth Davison, et al. “Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients.” Int J Cardiol 204 (February 1, 2016): 164–71. https://doi.org/10.1016/j.ijcard.2015.11.141.

Fiuzat, Mona, Daniel Wojdyla, Ileana Pina, Kirkwood Adams, David Whellan, and Christopher M. O’Connor. “Heart Rate or Beta-Blocker Dose? Association With Outcomes in Ambulatory Heart Failure Patients With Systolic Dysfunction: Results From the HF-ACTION Trial.” Jacc Heart Fail 4, no. 2 (February 2016): 109–15. https://doi.org/10.1016/j.jchf.2015.09.002.

Maaten, Jozine M. ter, Mattia A. E. Valente, Marco Metra, Noemi Bruno, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “A combined clinical and biomarker approach to predict diuretic response in acute heart failure.” Clin Res Cardiol 105, no. 2 (February 2016): 145–53. https://doi.org/10.1007/s00392-015-0896-2.

Mark, Daniel B., and Christopher M. O’Connor. “When Business and Science Clash, How Can We Avoid Harming Patients?: The Case of AVOID-HF.” Jacc Heart Fail 4, no. 2 (February 2016): 106–8. https://doi.org/10.1016/j.jchf.2015.09.001.

Mentz, Robert J., Vic Hasselblad, Adam D. DeVore, Marco Metra, Adriaan A. Voors, Paul W. Armstrong, Justin A. Ezekowitz, et al. “Torsemide Versus Furosemide in Patients With Acute Heart Failure (from the ASCEND-HF Trial).” Am J Cardiol 117, no. 3 (February 1, 2016): 404–11. https://doi.org/10.1016/j.amjcard.2015.10.059.

O’Connor, Christopher M. “Death of the Heart Failure Clinical Investigator: Molecules and Receptors Win Nobel Prizes, Clinical Investigation Improves Survival.” Jacc Heart Fail 4, no. 2 (February 2016): 162–63. https://doi.org/10.1016/j.jchf.2015.12.001.

Ahmad, Tariq, Jacob P. Kelly, Robert W. McGarrah, Anne S. Hellkamp, Mona Fiuzat, Jeffrey M. Testani, Teresa S. Wang, et al. “Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support.” J Am Coll Cardiol 67, no. 3 (January 26, 2016): 291–99. https://doi.org/10.1016/j.jacc.2015.10.079.

Bruno, Noemi, Jozine M. ter Maaten, Ekaterina S. Ovchinnikova, Eline L. Vegter, Mattia A. E. Valente, Peter van der Meer, Rudolf A. de Boer, et al. “MicroRNAs relate to early worsening of renal function in patients with acute heart failure.” Int J Cardiol 203 (January 15, 2016): 564–69. https://doi.org/10.1016/j.ijcard.2015.10.217.

Ahmad, Tariq, Nihar Desai, Francis Wilson, Phillip Schulte, Allison Dunning, Daniel Jacoby, Larry Allen, et al. “Clinical Implications of Cluster Analysis-Based Classification of Acute Decompensated Heart Failure and Correlation with Bedside Hemodynamic Profiles.” Plos One 11, no. 2 (2016): e0145881. https://doi.org/10.1371/journal.pone.0145881.

Mentz, Robert J., and Christopher M. O’Connor. “Pathophysiology and clinical evaluation of acute heart failure.” Nat Rev Cardiol 13, no. 1 (January 2016): 28–35. https://doi.org/10.1038/nrcardio.2015.134.

O’Connor, Christopher M. “Why Dr. Robert Califf's Nomination for Commissioner of the Food and Drug Administration Is Good for Heart Failure Patients.” Jacc Heart Fail 4, no. 1 (January 2016): 90–91. https://doi.org/10.1016/j.jchf.2015.11.004.

Tang, WH Wilson, Yuping Wu, Justin L. Grodin, Amy P. Hsu, Adrian F. Hernandez, Javed Butler, Marco Metra, et al. “Prognostic Value of Baseline and Changes in Circulating Soluble ST2 Levels and the Effects of Nesiritide in Acute Decompensated Heart Failure.” Jacc Heart Fail 4, no. 1 (January 2016): 68–77. https://doi.org/10.1016/j.jchf.2015.07.015.

Brunner-La Rocca, Hans-Peter, Luc Eurlings, A Mark Richards, James L. Januzzi, Matthias E. Pfisterer, Ulf Dahlström, Yigal M. Pinto, et al. “Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials.” Eur J Heart Fail 17, no. 12 (December 2015): 1252–61. https://doi.org/10.1002/ejhf.401.

O’Connor, Christopher M. “Heart Failure "End Result Cards": Solid B.” Jacc Heart Fail 3, no. 12 (December 2015): 1001–2. https://doi.org/10.1016/j.jchf.2015.10.004.

Cooper, Lauren B., Robert J. Mentz, Jie-Lena Sun, Phillip J. Schulte, Jerome L. Fleg, Lawton S. Cooper, Ileana L. Piña, et al. “Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION).” Circ Heart Fail 8, no. 6 (November 2015): 1044–51. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002327.

O’Connor, Christopher M. “Bundle Up for Value-Based Heart Failure Care.” Jacc Heart Fail 3, no. 11 (November 2015): 931–32. https://doi.org/10.1016/j.jchf.2015.09.003.

Samad, Zainab, Linda K. Shaw, Matthew Phelan, Mads Ersboll, Niels Risum, Hussein R. Al-Khalidi, Donald D. Glower, et al. “Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction.” Eur Heart J 36, no. 40 (October 21, 2015): 2733–41. https://doi.org/10.1093/eurheartj/ehv343.

Grodin, Justin L., Antonio L. Perez, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, G Michael Felker, et al. “Circulating Kidney Injury Molecule-1 Levels in Acute Heart Failure: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Jacc Heart Fail 3, no. 10 (October 2015): 777–85. https://doi.org/10.1016/j.jchf.2015.06.006.

O’Connor, Christopher M. “Physician-Leaders: A Call for Cardiovascular Specialists to Step Up.” Jacc Heart Fail 3, no. 10 (October 2015): 843–44. https://doi.org/10.1016/j.jchf.2015.08.004.

Felker, G Michael, Robert J. Mentz, Kirkwood F. Adams, Robert T. Cole, Gregory F. Egnaczyk, Chetan B. Patel, Mona Fiuzat, et al. “Tolvaptan in Patients Hospitalized With Acute Heart Failure: Rationale and Design of the TACTICS and the SECRET of CHF Trials.” Circ Heart Fail 8, no. 5 (September 2015): 997–1005. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002259.

Mentz, Robert J., Eric J. Velazquez, Marco Metra, Colleen McKendry, Karen Chiswell, Mona Fiuzat, Michael M. Givertz, Adriaan A. Voors, John R. Teerlink, and Christopher M. O’Connor. “Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial.” Future Cardiol 11, no. 5 (September 2015): 585–95. https://doi.org/10.2217/fca.15.56.

O’Connor, Christopher M. “What Is a Life Worth?: A Tribute to Dr. William Little, a Pioneer in the Understanding of Heart Failure With Preserved Ejection Fraction.” Jacc Heart Fail 3, no. 9 (September 2015): 734–35. https://doi.org/10.1016/j.jchf.2015.07.002.

Xiong, Glen L., Kevin Prybol, Stephen H. Boyle, Russell Hall, Robert D. Streilein, David C. Steffens, Ranga Krishnan, et al. “Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study.” Psychosom Med 77, no. 7 (September 2015): 808–15. https://doi.org/10.1097/PSY.0000000000000216.

Abualnaja, Seraj, Mohua Podder, Adrian F. Hernandez, John J. V. McMurray, Randall C. Starling, Christopher M. O’Connor, Robert M. Califf, Paul W. Armstrong, and Justin A. Ezekowitz. “Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) Trial.” J Am Heart Assoc 4, no. 8 (August 24, 2015): e002092. https://doi.org/10.1161/JAHA.115.002092.

O’Connor, Christopher M., and Tariq Ahmad. “The Role of Sodium and Chloride in Heart Failure: Does It Take Two to Tango?” J Am Coll Cardiol 66, no. 6 (August 11, 2015): 667–69. https://doi.org/10.1016/j.jacc.2015.05.070.

Dardas, Todd, Yanhong Li, Shelby D. Reed, Christopher M. O’Connor, David J. Whellan, Stephen J. Ellis, Kevin A. Schulman, William E. Kraus, Daniel E. Forman, and Wayne C. Levy. “Incremental and independent value of cardiopulmonary exercise test measures and the Seattle Heart Failure Model for prediction of risk in patients with heart failure.” J Heart Lung Transplant 34, no. 8 (August 2015): 1017–23. https://doi.org/10.1016/j.healun.2015.03.017.

Farzaneh-Far, Afshin, Linda K. Shaw, Allison Dunning, Jorge D. Oldan, Christopher M. O’Connor, and Salvador Borges-Neto. “Comparison of the prognostic value of regadenoson and adenosine myocardial perfusion imaging.” J Nucl Cardiol 22, no. 4 (August 2015): 600–607. https://doi.org/10.1007/s12350-015-0155-y.

Hess, Paul L., Linda K. Shaw, Sreekanth Vemulapalli, Robert Pagnanelli, Christopher M. O’Connor, and Salvador Borges-Neto. “An alternative method to examine the predictive value of mechanical dyssynchrony.” J Nucl Cardiol 22, no. 4 (August 2015): 686–89. https://doi.org/10.1007/s12350-015-0145-0.

Kelly, Jacob P., Robert J. Mentz, Vic Hasselblad, Justin A. Ezekowitz, Paul W. Armstrong, Faiez Zannad, G Michael Felker, Robert M. Califf, Christopher M. O’Connor, and Adrian F. Hernandez. “Worsening heart failure during hospitalization for acute heart failure: Insights from the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF).” Am Heart J 170, no. 2 (August 2015): 298–305. https://doi.org/10.1016/j.ahj.2015.04.007.

Khazanie, Prateeti, Gretchen M. Heizer, Vic Hasselblad, Paul W. Armstrong, Robert M. Califf, Justin Ezekowitz, Kenneth Dickstein, et al. “Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models.” Am Heart J 170, no. 2 (August 2015): 290–97. https://doi.org/10.1016/j.ahj.2015.04.006.

Maaten, Jozine M. ter, Allison M. Dunning, Mattia A. E. Valente, Kevin Damman, Justin A. Ezekowitz, Robert M. Califf, Randall C. Starling, et al. “Diuretic response in acute heart failure-an analysis from ASCEND-HF.” Am Heart J 170, no. 2 (August 2015): 313–21. https://doi.org/10.1016/j.ahj.2015.05.003.

O’Connor, Christopher M. “The Globalization of Heart Failure Research.” Jacc Heart Fail 3, no. 8 (August 2015): 657–58. https://doi.org/10.1016/j.jchf.2015.06.001.

O’Connor, Christopher M. “RESPONSE: Are We Committed to Training Fellows in Clinical Investigation?” J Am Coll Cardiol 66, no. 3 (July 21, 2015): 326–27.

Ahmad, Tariq, Emily C. O’Brien, Phillip J. Schulte, Susanna R. Stevens, Mona Fiuzat, Dalane W. Kitzman, Kirkwood F. Adams, et al. “Evaluation of the Incremental Prognostic Utility of Increasingly Complex Testing in Chronic Heart Failure.” Circ Heart Fail 8, no. 4 (July 2015): 709–16. https://doi.org/10.1161/CIRCHEARTFAILURE.114.001996.

Harinstein, Matthew E., Javed Butler, Stephen J. Greene, Gregg C. Fonarow, Norman L. Stockbridge, Christopher M. O’Connor, Marc A. Pfeffer, et al. “Site selection for heart failure clinical trials in the USA.” Heart Fail Rev 20, no. 4 (July 2015): 375–83. https://doi.org/10.1007/s10741-015-9473-z.

Mentz, Robert J., Marco Metra, Gad Cotter, Olga Milo, Colleen McKendry, Karen Chiswell, Beth A. Davison, et al. “Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial.” Eur J Heart Fail 17, no. 7 (July 2015): 697–706. https://doi.org/10.1002/ejhf.308.

O’Connor, Christopher M. “Why We Respect Randomized Controlled Clinical Trials in Heart Failure.” Jacc Heart Fail 3, no. 7 (July 2015): 576–77. https://doi.org/10.1016/j.jchf.2015.05.001.

Taylor, R. S., M. F. Piepoli, N. Smart, A. J. S. Coats, S. Ellis, H. Dalal, C. M. O’Connor, F. C. Warren, D. Whellan, and O. Ciani. “Erratum: Corrigendum to exercise training for chronic heart failure (ExTraMATCH II): Protocol for an individual participant data meta-analysis (Int J Cardiol. (2014) 174:3 (683-687) DOI: http://dx.doi.org/10.1016/j.ijcard.2014.04.203).” International Journal of Cardiology 193 (June 11, 2015): 93. https://doi.org/10.1016/j.ijcard.2014.11.220.

Boyle, Stephen H., Wayne R. Matson, Eric J. Velazquez, Zainab Samad, Redford B. Williams, Swati Sharma, Beena Thomas, Jennifer L. Wilson, Christopher O’Connor, and Wei Jiang. “Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction.” Metabolomics 11, no. 3 (June 1, 2015): 571–82. https://doi.org/10.1007/s11306-014-0718-y.

O’Connor, Christopher M. “Time for Recognition.” Jacc Heart Fail 3, no. 6 (June 2015): 508–9. https://doi.org/10.1016/j.jchf.2015.04.001.

Rosendorff, Clive, Daniel T. Lackland, Matthew Allison, Wilbert S. Aronow, Henry R. Black, Roger S. Blumenthal, Christopher P. Cannon, et al. “Treatment of hypertension in patients with coronary artery disease: A scientific statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension.” J Am Soc Hypertens 9, no. 6 (June 2015): 453–98. https://doi.org/10.1016/j.jash.2015.03.002.

Rosendorff, Clive, Daniel T. Lackland, Matthew Allison, Wilbert S. Aronow, Henry R. Black, Roger S. Blumenthal, Christopher P. Cannon, et al. “Treatment of hypertension in patients with coronary artery disease: a scientific statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension.” Hypertension 65, no. 6 (June 2015): 1372–1407. https://doi.org/10.1161/HYP.0000000000000018.

Givertz, Michael M., Kevin J. Anstrom, Margaret M. Redfield, Anita Deswal, Haissam Haddad, Javed Butler, WH Wilson Tang, et al. “Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study.” Circulation 131, no. 20 (May 19, 2015): 1763–71. https://doi.org/10.1161/CIRCULATIONAHA.114.014536.

Rosendorff, Clive, Daniel T. Lackland, Matthew Allison, Wilbert S. Aronow, Henry R. Black, Roger S. Blumenthal, Christopher P. Cannon, et al. “Treatment of Hypertension in Patients With Coronary Artery Disease: A Scientific Statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension.” J Am Coll Cardiol 65, no. 18 (May 12, 2015): 1998–2038. https://doi.org/10.1016/j.jacc.2015.02.038.

Rosendorff, Clive, Daniel T. Lackland, Matthew Allison, Wilbert S. Aronow, Henry R. Black, Roger S. Blumenthal, Christopher P. Cannon, et al. “Treatment of hypertension in patients with coronary artery disease: a scientific statement from the American Heart Association, American College of Cardiology, and American Society of Hypertension.” Circulation 131, no. 19 (May 12, 2015): e435–70. https://doi.org/10.1161/CIR.0000000000000207.

Davison, Beth A., Marco Metra, Gad Cotter, Barry M. Massie, John G. F. Cleland, Howard C. Dittrich, Christopher Edwards, et al. “Worsening Heart Failure Following Admission for Acute Heart Failure: A Pooled Analysis of the PROTECT and RELAX-AHF Studies.” Jacc Heart Fail 3, no. 5 (May 2015): 395–403. https://doi.org/10.1016/j.jchf.2015.01.007.

Mentz, Robert J., Jonathan Buggey, Mona Fiuzat, Mads K. Ersbøll, Phillip J. Schulte, Adam D. DeVore, Eric L. Eisenstein, Kevin J. Anstrom, Christopher M. OʼConnor, and Eric J. Velazquez. “Torsemide versus furosemide in heart failure patients: insights from Duke University Hospital.” J Cardiovasc Pharmacol 65, no. 5 (May 2015): 438–43. https://doi.org/10.1097/FJC.0000000000000212.

Mentz, Robert J., Michael A. Babyak, Vera Bittner, Jerome L. Fleg, Steven J. Keteyian, Ann M. Swank, Ileana L. Piña, et al. “Prognostic significance of depression in blacks with heart failure: insights from Heart Failure: a Controlled Trial Investigating Outcomes of Exercise Training.” Circ Heart Fail 8, no. 3 (May 2015): 497–503. https://doi.org/10.1161/CIRCHEARTFAILURE.114.001995.

O’Connor, Christopher M. “Medical editors' grand rounds: a discussion of timely topics and editorial emergencies.” Jacc Heart Fail 3, no. 5 (May 2015): 422–23. https://doi.org/10.1016/j.jchf.2015.02.001.

Kelly, Jacob P., Robert J. Mentz, Alexandre Mebazaa, Adriaan A. Voors, Javed Butler, Lothar Roessig, Mona Fiuzat, et al. “Patient selection in heart failure with preserved ejection fraction clinical trials.” J Am Coll Cardiol 65, no. 16 (April 28, 2015): 1668–82. https://doi.org/10.1016/j.jacc.2015.03.043.

Jiang, Wei, Stephen H. Boyle, Thomas L. Ortel, Zainab Samad, Eric J. Velazquez, Robert W. Harrison, Jennifer Wilson, et al. “Platelet aggregation and mental stress induced myocardial ischemia: Results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study.” Am Heart J 169, no. 4 (April 2015): 496-507.e1. https://doi.org/10.1016/j.ahj.2014.12.002.

O’Connor, Christopher M. “Reading RVUs: How can we meet the informational needs of cardiologists?” Jacc Heart Fail 3, no. 4 (April 2015): 340–41. https://doi.org/10.1016/j.jchf.2015.01.001.

Whellan, David J., William E. Kraus, Dalane W. Kitzman, Bridget Rooney, Steven J. Keteyian, Ileana L. Piña, Stephen J. Ellis, et al. “Authorship in a multicenter clinical trial: The Heart Failure-A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) Authorship and Publication (HAP) scoring system results.” Am Heart J 169, no. 4 (April 2015): 457-63.e6. https://doi.org/10.1016/j.ahj.2014.11.022.

Buggey, Jonathan, Robert J. Mentz, Bertram Pitt, Eric L. Eisenstein, Kevin J. Anstrom, Eric J. Velazquez, and Christopher M. O’Connor. “A reappraisal of loop diuretic choice in heart failure patients.” Am Heart J 169, no. 3 (March 2015): 323–33. https://doi.org/10.1016/j.ahj.2014.12.009.

Butler, Javed, Gregg C. Fonarow, Christopher O’Connor, Kirkwood Adams, Robert O. Bonow, Robert J. Cody, Sean P. Collins, et al. “Improving cardiovascular clinical trials conduct in the United States: recommendation from clinicians, researchers, sponsors, and regulators.” Am Heart J 169, no. 3 (March 2015): 305–14. https://doi.org/10.1016/j.ahj.2014.12.001.

Metra, Marco, Gad Cotter, Jill El-Khorazaty, Beth A. Davison, Olga Milo, Valentina Carubelli, Robert C. Bourge, et al. “Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study.” J Card Fail 21, no. 3 (March 2015): 179–88. https://doi.org/10.1016/j.cardfail.2014.12.012.

O’Connor, Christopher M. “Hop, skip, and jump: do we need phase II cardiovascular clinical trials?” Jacc Heart Fail 3, no. 3 (March 2015): 273–74. https://doi.org/10.1016/j.jchf.2014.12.003.

Mentz, Robert J., Susanna R. Stevens, Adam D. DeVore, Anuradha Lala, Justin M. Vader, Omar F. AbouEzzeddine, Prateeti Khazanie, et al. “Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure.” Jacc Heart Fail 3, no. 2 (February 2015): 97–107. https://doi.org/10.1016/j.jchf.2014.09.003.

O’Connor, Christopher M. “War and peace: the role of medical journals in the discussion of conflict.” Jacc Heart Fail 3, no. 2 (February 2015): 192. https://doi.org/10.1016/j.jchf.2014.11.002.

Jiang, W., S. H. Boyle, T. L. Ortel, Z. Samad, E. J. Velazquez, R. W. Harrison, J. Wilson, et al. “Platelet aggregation and mental stress induced myocardial ischemia: Results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study.” American Heart Journal 169, no. 4 (January 1, 2015): 496-507.e1. https://doi.org/10.1016/j.ahj.2014.12.002.

Metra, Marco, Robert J. Mentz, Karen Chiswell, Daniel M. Bloomfield, John G. F. Cleland, Gad Cotter, Beth A. Davison, et al. “Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial.” Eur J Heart Fail 17, no. 1 (January 2015): 109–18. https://doi.org/10.1002/ejhf.207.

O’Connor, Christopher M. “Conflict of interest and transparency: are the headlights misaligned?” Jacc Heart Fail 3, no. 1 (January 2015): 94. https://doi.org/10.1016/j.jchf.2014.10.001.

Tang, WH Wilson, Matthias Dupont, Adrian F. Hernandez, Adriaan A. Voors, Amy P. Hsu, G Michael Felker, Javed Butler, et al. “Comparative assessment of short-term adverse events in acute heart failure with cystatin C and other estimates of renal function: results from the ASCEND-HF trial.” Jacc Heart Fail 3, no. 1 (January 2015): 40–49. https://doi.org/10.1016/j.jchf.2014.06.014.

Yun, H., E. Delzell, K. G. Saag, M. L. Kilgore, M. A. Morrisey, P. Muntner, R. Matthews, et al. “Fractures and mortality in relation to different osteoporosis treatments.” Clinical and Experimental Rheumatology 33, no. 3 (January 1, 2015): 302–9.

Zeitler, Emily P., Jonathan P. Piccini, Anne S. Hellkamp, David J. Whellan, Kevin P. Jackson, Stephen J. Ellis, William E. Kraus, et al. “Exercise training and pacing status in patients with heart failure: results from HF-ACTION.” J Card Fail 21, no. 1 (January 2015): 60–67. https://doi.org/10.1016/j.cardfail.2014.10.004.

Das, Debraj, Jeffery A. Bakal, Cynthia M. Westerhout, Adrian F. Hernandez, Christopher M. O’Connor, Dan Atar, John J. V. McMurray, Paul W. Armstrong, and Justin A. Ezekowitz. “The association between meteorological events and acute heart failure: new insights from ASCEND-HF.” Int J Cardiol 177, no. 3 (December 20, 2014): 819–24. https://doi.org/10.1016/j.ijcard.2014.11.066.

Diepen, Sean van, Mohua Podder, Adrian F. Hernandez, Cynthia M. Westerhout, Paul W. Armstong, John J. V. McMurray, Zubin J. Eapen, et al. “Acute decompensated heart failure patients admitted to critical care units: insights from ASCEND-HF.” Int J Cardiol 177, no. 3 (December 20, 2014): 840–46. https://doi.org/10.1016/j.ijcard.2014.11.007.

Mentz, Robert J., Jacob P. Kelly, Thomas G. von Lueder, Adriaan A. Voors, Carolyn S. P. Lam, Martin R. Cowie, Keld Kjeldsen, et al. “Noncardiac comorbidities in heart failure with reduced versus preserved ejection fraction.” J Am Coll Cardiol 64, no. 21 (December 2, 2014): 2281–93. https://doi.org/10.1016/j.jacc.2014.08.036.

Cotter, Gad, Marco Metra, Beth A. Davison, Stefanie Senger, Robert C. Bourge, John G. F. Cleland, Guillaume Jondeau, et al. “Worsening heart failure, a critical event during hospital admission for acute heart failure: results from the VERITAS study.” Eur J Heart Fail 16, no. 12 (December 2014): 1362–71. https://doi.org/10.1002/ejhf.186.

O’Connor, Christopher M. “Precision and predictive medicine: lessons learned from our oncology colleagues.” Jacc Heart Fail 2, no. 6 (December 2014): 671. https://doi.org/10.1016/j.jchf.2014.10.004.

Mentz, Robert J., James A. Tulsky, Bradi B. Granger, Kevin J. Anstrom, Patricia A. Adams, Gwen C. Dodson, Mona Fiuzat, et al. “The palliative care in heart failure trial: rationale and design.” Am Heart J 168, no. 5 (November 2014): 645-651.e1. https://doi.org/10.1016/j.ahj.2014.07.018.

Patel, Priyesh A., Gretchen Heizer, Christopher M. O’Connor, Phillip J. Schulte, Kenneth Dickstein, Justin A. Ezekowitz, Paul W. Armstrong, et al. “Hypotension during hospitalization for acute heart failure is independently associated with 30-day mortality: findings from ASCEND-HF.” Circ Heart Fail 7, no. 6 (November 2014): 918–25. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000872.

Ahmad, Tariq, Michael J. Pencina, Phillip J. Schulte, Emily O’Brien, David J. Whellan, Ileana L. Piña, Dalane W. Kitzman, Kerry L. Lee, Christopher M. O’Connor, and G Michael Felker. “Clinical implications of chronic heart failure phenotypes defined by cluster analysis.” J Am Coll Cardiol 64, no. 17 (October 28, 2014): 1765–74. https://doi.org/10.1016/j.jacc.2014.07.979.

Samad, Zainab, Stephen Boyle, Mads Ersboll, Amit N. Vora, Ye Zhang, Richard C. Becker, Redford Williams, et al. “Sex differences in platelet reactivity and cardiovascular and psychological response to mental stress in patients with stable ischemic heart disease: insights from the REMIT study.” J Am Coll Cardiol 64, no. 16 (October 21, 2014): 1669–78. https://doi.org/10.1016/j.jacc.2014.04.087.

Rogers, Joseph G., and Christopher M. O’Connor. “The changing landscape of advanced heart failure therapeutics.” J Am Coll Cardiol 64, no. 14 (October 7, 2014): 1416–17. https://doi.org/10.1016/j.jacc.2014.04.085.

Ahmad, Tariq, Mona Fiuzat, Michael J. Pencina, Nancy L. Geller, Faiez Zannad, John G. F. Cleland, James V. Snider, et al. “Charting a roadmap for heart failure biomarker studies.” Jacc Heart Fail 2, no. 5 (October 2014): 477–88. https://doi.org/10.1016/j.jchf.2014.02.005.

Felker, G Michael, Tariq Ahmad, Kevin J. Anstrom, Kirkwood F. Adams, Lawton S. Cooper, Justin A. Ezekowitz, Mona Fiuzat, et al. “Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure.” Jacc Heart Fail 2, no. 5 (October 2014): 457–65. https://doi.org/10.1016/j.jchf.2014.05.007.

O’Connor, Christopher. “Are models better than cardiologists?: An analysis of risk prediction in heart failure.” Jacc Heart Fail 2, no. 5 (October 2014): 536–37. https://doi.org/10.1016/j.jchf.2014.07.002.

Patel, Chetan B., Adam D. DeVore, G Michael Felker, Daniel M. Wojdyla, Adrian F. Hernandez, Carmelo A. Milano, Christopher M. O’Connor, and Joseph G. Rogers. “Characteristics and outcomes of patients with heart failure and discordant findings by right-sided heart catheterization and cardiopulmonary exercise testing.” Am J Cardiol 114, no. 7 (October 1, 2014): 1059–64. https://doi.org/10.1016/j.amjcard.2014.07.022.

Whellan, David J., Jay L. Goldstein, Byron L. Cryer, Glenn M. Eisen, Angel Lanas, Alan B. Miller, James M. Scheiman, John G. Fort, Ying Zhang, and Christopher O’Connor. “PA32540 (a coordinated-delivery tablet of enteric-coated aspirin 325 mg and immediate-release omeprazole 40 mg) versus enteric-coated aspirin 325 mg alone in subjects at risk for aspirin-associated gastric ulcers: results of two 6-month, phase 3 studies.” Am Heart J 168, no. 4 (October 2014): 495-502.e4. https://doi.org/10.1016/j.ahj.2014.05.017.

Deursen, Vincent M. van, Adrian F. Hernandez, Amanda Stebbins, Vic Hasselblad, Justin A. Ezekowitz, Robert M. Califf, Stephen S. Gottlieb, et al. “Nesiritide, renal function, and associated outcomes during hospitalization for acute decompensated heart failure: results from the Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure (ASCEND-HF).” Circulation 130, no. 12 (September 16, 2014): 958–65. https://doi.org/10.1161/CIRCULATIONAHA.113.003046.

Ziaeian, Boback, Yan Zhang, Nancy M. Albert, Anne B. Curtis, Mihai Gheorghiade, J Thomas Heywood, Mandeep R. Mehra, et al. “Clinical effectiveness of CRT and ICD therapy in heart failure patients by racial/ethnic classification: insights from the IMPROVE HF registry.” J Am Coll Cardiol 64, no. 8 (August 26, 2014): 797–807. https://doi.org/10.1016/j.jacc.2014.05.060.

Jones, Lee W., Pamela S. Douglas, Michel G. Khouri, John R. Mackey, Daniel Wojdyla, William E. Kraus, David J. Whellan, and Christopher M. O’Connor. “Safety and efficacy of aerobic training in patients with cancer who have heart failure: an analysis of the HF-ACTION randomized trial.” J Clin Oncol 32, no. 23 (August 10, 2014): 2496–2502. https://doi.org/10.1200/JCO.2013.53.5724.

Li, Yanhong, Wayne C. Levy, Matthew P. Neilson, Stephen J. Ellis, David J. Whellan, Kevin A. Schulman, Christopher M. O’Connor, and Shelby D. Reed. “Associations between seattle heart failure model scores and medical resource use and costs: findings from HF-ACTION.” J Card Fail 20, no. 8 (August 2014): 541–47. https://doi.org/10.1016/j.cardfail.2014.05.009.

Mentz, Robert J., Samuel Broderick, Linda K. Shaw, Karen Chiswell, Mona Fiuzat, and Christopher M. O’Connor. “Persistent angina pectoris in ischaemic cardiomyopathy: increased rehospitalization and major adverse cardiac events.” Eur J Heart Fail 16, no. 8 (August 2014): 854–60. https://doi.org/10.1002/ejhf.130.

O’Connor, Christopher. “Heart failure: where the paths cross.” Jacc Heart Fail 2, no. 4 (August 2014): 427. https://doi.org/10.1016/j.jchf.2014.05.001.

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Wolfe, Frederick, Marcy B. Bolster, Christopher M. O’Connor, Kaleb Michaud, Kenneth W. Lyles, and Cathleen S. Colón-Emeric. “Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis.” J Bone Miner Res 28, no. 5 (May 2013): 984–91. https://doi.org/10.1002/jbmr.1792.

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Jones, W Schuyler, Manesh R. Patel, Sara A. Holleran, J Kevin Harrison, Christopher M. O’Connor, and Harry R. Phillips. “Trends in the use of diagnostic coronary angiography, percutaneous coronary intervention, and coronary artery bypass graft surgery across North Carolina.” Am Heart J 162, no. 5 (November 2011): 932–37. https://doi.org/10.1016/j.ahj.2011.08.015.

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Povsic, Thomas J., Christopher M. O’Connor, Timothy Henry, Andrew Taussig, Dean J. Kereiakes, F David Fortuin, Alan Niederman, et al. “A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in patients with chronic heart failure after myocardial infarction.” Am Heart J 162, no. 4 (October 2011): 654-662.e1. https://doi.org/10.1016/j.ahj.2011.07.020.

Kociol, Robb D., John R. Horton, Gregg C. Fonarow, Eric M. Reyes, Linda K. Shaw, Christopher M. O’Connor, G Michael Felker, and Adrian F. Hernandez. “Admission, discharge, or change in B-type natriuretic peptide and long-term outcomes: data from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF) linked to Medicare claims.” Circ Heart Fail 4, no. 5 (September 2011): 628–36. https://doi.org/10.1161/CIRCHEARTFAILURE.111.962290.

West, Ryenn, Li Liang, Gregg C. Fonarow, Robb Kociol, Roger M. Mills, Christopher M. O’Connor, and Adrian F. Hernandez. “Characterization of heart failure patients with preserved ejection fraction: a comparison between ADHERE-US registry and ADHERE-International registry.” Eur J Heart Fail 13, no. 9 (September 2011): 945–52. https://doi.org/10.1093/eurjhf/hfr064.

O’Connor, Christopher M., Mona Fiuzat, Karl Swedberg, Michael Caron, Bruce Koch, Peter E. Carson, Wendy Gattis-Stough, Gordon W. Davis, and Michael R. Bristow. “Influence of global region on outcomes in heart failure β-blocker trials.” J Am Coll Cardiol 58, no. 9 (August 23, 2011): 915–22. https://doi.org/10.1016/j.jacc.2011.03.057.

Jones, W Schuyler, Robert Clare, Stephen J. Ellis, James S. Mills, David L. Fischman, William E. Kraus, David J. Whellan, Christopher M. O’Connor, and Manesh R. Patel. “Effect of peripheral arterial disease on functional and clinical outcomes in patients with heart failure (from HF-ACTION).” Am J Cardiol 108, no. 3 (August 1, 2011): 380–84. https://doi.org/10.1016/j.amjcard.2011.03.057.

Shah, Monica R., Robert M. Califf, Anju Nohria, Manju Bhapkar, Margaret Bowers, Donna M. Mancini, Mona Fiuzat, Lynne W. Stevenson, and Christopher M. O’Connor. “The STARBRITE trial: a randomized, pilot study of B-type natriuretic peptide-guided therapy in patients with advanced heart failure.” J Card Fail 17, no. 8 (August 2011): 613–21. https://doi.org/10.1016/j.cardfail.2011.04.012.

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Metra, Marco, Christopher M. O’Connor, Beth A. Davison, John G. F. Cleland, Piotr Ponikowski, John R. Teerlink, Adriaan A. Voors, et al. “Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study.” Eur Heart J 32, no. 12 (June 2011): 1519–34. https://doi.org/10.1093/eurheartj/ehr042.

Felker, G. M., E. Braunwald, and C. M. O’Connor. “The authors reply.” New England Journal of Medicine 364, no. 21 (May 26, 2011): 2069. https://doi.org/10.1056/NEJMc1103406.

Voors, Adriaan A., Howard C. Dittrich, Barry M. Massie, Paul DeLucca, George A. Mansoor, Marco Metra, Gad Cotter, et al. “Effects of the adenosine A1 receptor antagonist rolofylline on renal function in patients with acute heart failure and renal dysfunction: results from PROTECT (Placebo-Controlled Randomized Study of the Selective Adenosine A1 Receptor Antagonist Rolofylline for Patients Hospitalized with Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function).” J Am Coll Cardiol 57, no. 19 (May 10, 2011): 1899–1907. https://doi.org/10.1016/j.jacc.2010.11.057.

Bettari, Luca, Mona Fiuzat, Richard Becker, G Michael Felker, Marco Metra, and Christopher M. O’Connor. “Thromboembolism and antithrombotic therapy in patients with heart failure in sinus rhythm: current status and future directions.” Circ Heart Fail 4, no. 3 (May 2011): 361–68. https://doi.org/10.1161/CIRCHEARTFAILURE.110.959957.

Fiuzat, M., and C. M. O’Connor. “Bucindolol: new hopes from reviewing past data.” Drugs Today (Barc) 47, no. 5 (May 2011): 347–51. https://doi.org/10.1358/dot.2011.47.5.1579112.

Velazquez, Eric J., Kerry L. Lee, Marek A. Deja, Anil Jain, George Sopko, Andrey Marchenko, Imtiaz S. Ali, et al. “Coronary-artery bypass surgery in patients with left ventricular dysfunction.” N Engl J Med 364, no. 17 (April 28, 2011): 1607–16. https://doi.org/10.1056/NEJMoa1100356.

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Sherwood, Andrew, Christopher M. O’Connor, Faye S. Routledge, Alan L. Hinderliter, Lana L. Watkins, Michael A. Babyak, Gary G. Koch, et al. “Coping effectively with heart failure (COPE-HF): design and rationale of a telephone-based coping skills intervention.” J Card Fail 17, no. 3 (March 2011): 201–7. https://doi.org/10.1016/j.cardfail.2010.11.001.

Jiang, Wei, Ranga Krishnan, Maragatha Kuchibhatla, Michael S. Cuffe, Carolyn Martsberger, Rebekka M. Arias, Christopher M. O’Connor, and Christopher M. SADHART-CHF Investigators. “Characteristics of depression remission and its relation with cardiovascular outcome among patients with chronic heart failure (from the SADHART-CHF Study).” Am J Cardiol 107, no. 4 (February 15, 2011): 545–51. https://doi.org/10.1016/j.amjcard.2010.10.013.

Gheorghiade, Mihai, Peter S. Pang, Christopher M. O’Connor, Krishna Prasad, John McMurray, John R. Teerlink, Mona Fiuzat, Hani Sabbah, and Michel Komajda. “Clinical development of pharmacologic agents for acute heart failure syndromes: a proposal for a mechanistic translational phase.” Am Heart J 161, no. 2 (February 2011): 224–32. https://doi.org/10.1016/j.ahj.2010.10.023.

O’Connor, Christopher M., Walter J. Koch, and Douglas L. Mann. “Highlights of the 2010 scientific sessions of the Heart Failure Society of America, San Diego, California, September 12-15, 2010.” J Card Fail 17, no. 2 (February 2011): 92–99. https://doi.org/10.1016/j.cardfail.2010.12.002.

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Adams, Kirkwood F., Mandeep R. Mehra, Ron M. Oren, Christopher M. O’Connor, Jun R. Chiong, Jalal K. Ghali, Daniel J. Lenihan, et al. “Prospective evaluation of the association between cardiac troponin T and markers of disturbed erythropoiesis in patients with heart failure.” Am Heart J 160, no. 6 (December 2010): 1142–48. https://doi.org/10.1016/j.ahj.2010.07.033.

Echols, Melvin R., and Christopher M. O’Connor. “Depression after myocardial infarction.” Curr Heart Fail Rep 7, no. 4 (December 2010): 185–93. https://doi.org/10.1007/s11897-010-0024-6.

Fiuzat, Mona, Linda K. Shaw, Laine Thomas, G Michael Felker, and Christopher M. O’Connor. “United States stock market performance and acute myocardial infarction rates in 2008-2009 (from the Duke Databank for Cardiovascular Disease).” Am J Cardiol 106, no. 11 (December 1, 2010): 1545–49. https://doi.org/10.1016/j.amjcard.2010.07.027.

Walsh, Mary Norine, Clyde W. Yancy, Nancy M. Albert, Anne B. Curtis, Mihai Gheorghiade, J Thomas Heywood, Patches Johnson Inge, et al. “Equitable improvement for women and men in the use of guideline-recommended therapies for heart failure: findings from IMPROVE HF.” J Card Fail 16, no. 12 (December 2010): 940–49. https://doi.org/10.1016/j.cardfail.2010.07.250.

Ponikowski, Piotr, Veselin Mitrovic, Christopher M. O’Connor, Howard Dittrich, Gad Cotter, Barry M. Massie, Michael M. Givertz, et al. “Haemodynamic effects of rolofylline in the treatment of patients with heart failure and impaired renal function.” Eur J Heart Fail 12, no. 11 (November 2010): 1238–46. https://doi.org/10.1093/eurjhf/hfq137.

Wu, Audrey H., Jalal K. Ghali, Gerald W. Neuberg, Christopher M. O’Connor, Peter E. Carson, and Wayne C. Levy. “Uric acid level and allopurinol use as risk markers of mortality and morbidity in systolic heart failure.” Am Heart J 160, no. 5 (November 2010): 928–33. https://doi.org/10.1016/j.ahj.2010.08.006.

Massie, Barry M., Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, Gad Cotter, Beth Davison Weatherley, et al. “Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure.” N Engl J Med 363, no. 15 (October 7, 2010): 1419–28. https://doi.org/10.1056/NEJMoa0912613.

Carson, Peter, Mona Fiuzat, Christopher O’Connor, Inder Anand, Jonathan Plehn, Jo Ann Lindenfeld, Marc Silver, et al. “Determination of hospitalization type by investigator case report form or adjudication committee in a large heart failure clinical trial (β-Blocker Evaluation of Survival Trial [BEST]).” Am Heart J 160, no. 4 (October 2010): 649–54. https://doi.org/10.1016/j.ahj.2010.07.004.

Rouleau, Jean L., Robert E. Michler, Eric J. Velazquez, Jae K. Oh, Christopher M. O’Connor, Patrice Desvigne-Nickens, George Sopko, Kerry L. Lee, and Robert H. Jones. “The STICH trial: evidence-based conclusions.” Eur J Heart Fail 12, no. 10 (October 2010): 1028–30. https://doi.org/10.1093/eurjhf/hfq140.

Kociol, Robb D., Peter S. Pang, Mihai Gheorghiade, Gregg C. Fonarow, Christopher M. O’Connor, and G Michael Felker. “Troponin elevation in heart failure prevalence, mechanisms, and clinical implications.” J Am Coll Cardiol 56, no. 14 (September 28, 2010): 1071–78. https://doi.org/10.1016/j.jacc.2010.06.016.

Gottlieb, Stephen S., Michael M. Givertz, Marco Metra, Kevin Gergich, Steven Bird, Charlotte Jones-Burton, Barry Massie, et al. “The effects of adenosine A(1) receptor antagonism in patients with acute decompensated heart failure and worsening renal function: the REACH UP study.” J Card Fail 16, no. 9 (September 2010): 714–19. https://doi.org/10.1016/j.cardfail.2010.04.006.

Heywood, J Thomas, Gregg C. Fonarow, Clyde W. Yancy, Nancy M. Albert, Anne B. Curtis, Mihai Gheorghiade, Patches Johnson Inge, et al. “Comparison of medical therapy dosing in outpatients cared for in cardiology practices with heart failure and reduced ejection fraction with and without device therapy: report from IMPROVE HF.” Circ Heart Fail 3, no. 5 (September 2010): 596–605. https://doi.org/10.1161/CIRCHEARTFAILURE.109.912683.

Watkins, Lana L., James A. Blumenthal, Michael A. Babyak, Jonathan R. T. Davidson, Charles B. McCants, Christopher O’Connor, and Michael H. Sketch. “Phobic anxiety and increased risk of mortality in coronary heart disease.” Psychosom Med 72, no. 7 (September 2010): 664–71. https://doi.org/10.1097/PSY.0b013e3181e9f357.

O’Connor, Christopher M., Wei Jiang, Maragatha Kuchibhatla, Susan G. Silva, Michael S. Cuffe, Dwayne D. Callwood, Bosh Zakhary, et al. “Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial.” J Am Coll Cardiol 56, no. 9 (August 24, 2010): 692–99. https://doi.org/10.1016/j.jacc.2010.03.068.

Fonarow, Gregg C., Nancy M. Albert, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, J Thomas Heywood, Mark L. McBride, et al. “Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).” Circulation 122, no. 6 (August 10, 2010): 585–96. https://doi.org/10.1161/CIRCULATIONAHA.109.934471.

Jones, Robert H., Harvey White, Eric J. Velazquez, Linda K. Shaw, Ricardo Pietrobon, Julio A. Panza, Robert O. Bonow, George Sopko, Christopher M. O’Connor, and Jean-Lucien Rouleau. “STICH (Surgical Treatment for Ischemic Heart Failure) trial enrollment.” J Am Coll Cardiol 56, no. 6 (August 3, 2010): 490–98. https://doi.org/10.1016/j.jacc.2009.11.102.

Povsic, Thomas J., and Christopher M. O’Connor. “Cell therapy for heart failure: the need for a new therapeutic strategy.” Expert Rev Cardiovasc Ther 8, no. 8 (August 2010): 1107–26. https://doi.org/10.1586/erc.10.99.

West, Ryenn L., Adrian F. Hernandez, Christopher M. O’Connor, Randall C. Starling, and Robert M. Califf. “A review of dyspnea in acute heart failure syndromes.” Am Heart J 160, no. 2 (August 2010): 209–14. https://doi.org/10.1016/j.ahj.2010.05.020.

O’Connor, Christopher M., and Mona Fiuzat. “Is rehospitalization after heart failure admission a marker of poor quality? Time for re-evaluation.” J Am Coll Cardiol 56, no. 5 (July 27, 2010): 369–71. https://doi.org/10.1016/j.jacc.2010.02.054.

Peacock, W Frank, Eugene Braunwald, William Abraham, Nancy Albert, John Burnett, Rob Christenson, Sean Collins, et al. “National Heart, Lung, and Blood Institute working group on emergency department management of acute heart failure: research challenges and opportunities.” J Am Coll Cardiol 56, no. 5 (July 27, 2010): 343–51. https://doi.org/10.1016/j.jacc.2010.03.051.

Piccini, Jonathan P., Aijing Z. Starr, John R. Horton, Linda K. Shaw, Kerry L. Lee, Sana M. Al-Khatib, Ami E. Iskandrian, Christopher M. O’Connor, and Salvador Borges-Neto. “Single-photon emission computed tomography myocardial perfusion imaging and the risk of sudden cardiac death in patients with coronary disease and left ventricular ejection fraction>35%.” J Am Coll Cardiol 56, no. 3 (July 13, 2010): 206–14. https://doi.org/10.1016/j.jacc.2010.01.061.

Adams, Kirkwood F., G Michael Felker, Ghassan Fraij, J Herbert Patterson, and Christopher M. O’Connor. “Biomarker guided therapy for heart failure: focus on natriuretic peptides.” Heart Fail Rev 15, no. 4 (July 2010): 351–70. https://doi.org/10.1007/s10741-009-9139-9.

Gaziano, J Michael, Anthony H. Cincotta, Christopher M. O’Connor, Michael Ezrokhi, Dean Rutty, Z. J. Ma, and Richard E. Scranton. “Randomized clinical trial of quick-release bromocriptine among patients with type 2 diabetes on overall safety and cardiovascular outcomes.” Diabetes Care 33, no. 7 (July 2010): 1503–8. https://doi.org/10.2337/dc09-2009.

Kong, Melissa H., Linda K. Shaw, Christopher O’Connor, Robert M. Califf, Michael A. Blazing, and Sana M. Al-Khatib. “Is rhythm-control superior to rate-control in patients with atrial fibrillation and diastolic heart failure?” Ann Noninvasive Electrocardiol 15, no. 3 (July 2010): 209–17. https://doi.org/10.1111/j.1542-474X.2010.00365.x.

McMurray, J. J. V., I. S. Anand, R. Diaz, A. P. Maggioni, C. O’Connor, M. A. Pfeffer, K. R. Polu, et al. “Erratum: Design of the reduction of events with darbepoetin alfa in heart failure (RED-HF): A phase III, anaemia correction, morbidity-mortality trial (European Journal of Heart Failure (2009) 11 (795-801)).” European Journal of Heart Failure 12, no. 7 (July 1, 2010): 765. https://doi.org/10.1093/eurjhf/hfq067.

Reed, Shelby D., David J. Whellan, Yanhong Li, Joëlle Y. Friedman, Stephen J. Ellis, Ileana L. Piña, Sharon J. Settles, et al. “Economic evaluation of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) randomized controlled trial: an exercise training study of patients with chronic heart failure.” Circ Cardiovasc Qual Outcomes 3, no. 4 (July 2010): 374–81. https://doi.org/10.1161/CIRCOUTCOMES.109.907287.

Wang, Norman C., Jonathan P. Piccini, Marvin A. Konstam, Aldo P. Maggioni, Brian Traver, Karl Swedberg, James E. Udelson, et al. “Implantable cardioverter-defibrillators in patients hospitalized for heart failure with chronically reduced left ventricular ejection fraction.” Am J Ther 17, no. 4 (July 2010): e78–87. https://doi.org/10.1097/MJT.0b013e3181e70a65.

Albert, Nancy M., Gregg C. Fonarow, Clyde W. Yancy, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, J Thomas Heywood, et al. “Outpatient cardiology practices with advanced practice nurses and physician assistants provide similar delivery of recommended therapies (findings from IMPROVE HF).” Am J Cardiol 105, no. 12 (June 15, 2010): 1773–79. https://doi.org/10.1016/j.amjcard.2010.01.360.

Allen, Larry A., Aslan T. Turer, Tracy Dewald, Wendy Gattis Stough, Gadi Cotter, and Christopher M. O’Connor. “Continuous versus bolus dosing of Furosemide for patients hospitalized for heart failure.” Am J Cardiol 105, no. 12 (June 15, 2010): 1794–97. https://doi.org/10.1016/j.amjcard.2010.01.355.

Steffens, David C., David C. Wei Jiang, K Ranga R. Krishnan, Edward D. Karoly, Matthew W. Mitchell, Christopher M. O’Connor, and Rima Kaddurah-Daouk. “Metabolomic differences in heart failure patients with and without major depression.” J Geriatr Psychiatry Neurol 23, no. 2 (June 2010): 138–46. https://doi.org/10.1177/0891988709358592.

Xiong, Glen L., Wei Jiang, Robert M. Clare, Linda K. Shaw, Peter K. Smith, Christopher M. O’Connor, K. Ranga, R. Krishnan, and L. Kristin Newby. “Safety of selective serotonin reuptake inhibitor use prior to coronary artery bypass grafting.” Clin Cardiol 33, no. 6 (June 2010): E94–98. https://doi.org/10.1002/clc.20621.

Metra, Marco, John G. Cleland, Beth Davison Weatherley, Howard C. Dittrich, Michael M. Givertz, Barry M. Massie, Christopher M. O’Connor, et al. “Dyspnoea in patients with acute heart failure: an analysis of its clinical course, determinants, and relationship to 60-day outcomes in the PROTECT pilot study.” Eur J Heart Fail 12, no. 5 (May 2010): 499–507. https://doi.org/10.1093/eurjhf/hfq021.

O’Connor, Christopher M., Alan B. Miller, John E. A. Blair, Marvin A. Konstam, Patricia Wedge, Maria C. Bahit, Peter Carson, et al. “Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction: results from Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) program.” Am Heart J 159, no. 5 (May 2010): 841-849.e1. https://doi.org/10.1016/j.ahj.2010.02.023.

Whellan, David J., Kevin T. Ousdigian, Sana M. Al-Khatib, Wenji Pu, Shantanu Sarkar, Charles B. Porter, Behzad B. Pavri, Christopher M. O’Connor, and Christopher M. PARTNERS Study Investigators. “Combined heart failure device diagnostics identify patients at higher risk of subsequent heart failure hospitalizations: results from PARTNERS HF (Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure) study.” J Am Coll Cardiol 55, no. 17 (April 27, 2010): 1803–10. https://doi.org/10.1016/j.jacc.2009.11.089.

Heywood, J Thomas, Gregg C. Fonarow, Clyde W. Yancy, Nancy M. Albert, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, et al. “Influence of renal function on the use of guideline-recommended therapies for patients with heart failure.” Am J Cardiol 105, no. 8 (April 15, 2010): 1140–46. https://doi.org/10.1016/j.amjcard.2009.12.016.

Walsh, Mary Norine, Clyde W. Yancy, Nancy M. Albert, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, J Thomas Heywood, et al. “Electronic health records and quality of care for heart failure.” Am Heart J 159, no. 4 (April 2010): 635-642.e1. https://doi.org/10.1016/j.ahj.2010.01.006.

O’Connor, Christopher M., Vic Hasselblad, Rajendra H. Mehta, Gudaye Tasissa, Robert M. Califf, Mona Fiuzat, Joseph G. Rogers, Carl V. Leier, and Lynne W. Stevenson. “Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness) risk model and discharge score.” J Am Coll Cardiol 55, no. 9 (March 2, 2010): 872–78. https://doi.org/10.1016/j.jacc.2009.08.083.

Felker, G Michael, Peter S. Pang, Kirkwood F. Adams, John G. F. Cleland, Gad Cotter, Kenneth Dickstein, Gerasimos S. Filippatos, et al. “Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward.” Circ Heart Fail 3, no. 2 (March 2010): 314–25. https://doi.org/10.1161/CIRCHEARTFAILURE.109.893222.

Blumenthal, James A., and Christopher O’Connor. “No laughing matter.” J Am Coll Cardiol 55, no. 8 (February 23, 2010): 836. https://doi.org/10.1016/j.jacc.2009.09.048.

Albert, Nancy M., Gregg C. Fonarow, Clyde W. Yancy, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, J Thomas Heywood, et al. “Influence of dedicated heart failure clinics on delivery of recommended therapies in outpatient cardiology practices: findings from the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).” Am Heart J 159, no. 2 (February 2010): 238–44. https://doi.org/10.1016/j.ahj.2009.11.022.

Levy, Phillip D., Deepa Nandyal, Robert D. Welch, Jie Lena Sun, Karen Pieper, Jalal K. Ghali, Gregg C. Fonarow, Mihai Gheorghiade, and Christopher M. O’Connor. “Does aspirin use adversely influence intermediate-term postdischarge outcomes for hospitalized patients who are treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers? Findings from Organized Program to Facilitate Life-Saving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).” Am Heart J 159, no. 2 (February 2010): 222-230.e2. https://doi.org/10.1016/j.ahj.2009.11.009.

Yancy, Clyde W., Gregg C. Fonarow, Nancy M. Albert, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, J Thomas Heywood, et al. “Adherence to guideline-recommended adjunctive heart failure therapies among outpatient cardiology practices (findings from IMPROVE HF).” Am J Cardiol 105, no. 2 (January 15, 2010): 255–60. https://doi.org/10.1016/j.amjcard.2009.08.681.

Cotter, Gad, Marco Metra, Beth Davison Weatherley, Howard C. Dittrich, Barry M. Massie, Piotr Ponikowski, Daniel M. Bloomfield, and Christopher M. O’Connor. “Physician-determined worsening heart failure: a novel definition for early worsening heart failure in patients hospitalized for acute heart failure--association with signs and symptoms, hospitalization duration, and 60-day outcomes.” Cardiology 115, no. 1 (2010): 29–36. https://doi.org/10.1159/000249280.

French, John K., Anne S. Hellkamp, Paul W. Armstrong, Eric Cohen, Neil S. Kleiman, Christopher M. O’Connor, David R. Holmes, Judith S. Hochman, Christopher B. Granger, and Kenneth W. Mahaffey. “Mechanical complications after percutaneous coronary intervention in ST-elevation myocardial infarction (from APEX-AMI).” Am J Cardiol 105, no. 1 (January 1, 2010): 59–63. https://doi.org/10.1016/j.amjcard.2009.08.653.

Hernandez, Adrian F., Gregg C. Fonarow, Bradley G. Hammill, Sana M. Al-Khatib, Clyde W. Yancy, Christopher M. O’Connor, Kevin A. Schulman, Eric D. Peterson, and Lesley H. Curtis. “Clinical effectiveness of implantable cardioverter-defibrillators among medicare beneficiaries with heart failure.” Circ Heart Fail 3, no. 1 (January 2010): 7–13. https://doi.org/10.1161/CIRCHEARTFAILURE.109.884395.

O’Connor, C. M., W. J. Koch, and D. L. Mann. “Highlights of the 2009 Scientific Sessions of the Heart Failure Society of America, Boston, MA, September 13-16, 2009.” Journal of Cardiac Failure 16, no. 1 (January 1, 2010): 2–8. https://doi.org/10.1016/j.cardfail.2009.11.001.

Weatherley, Beth Davison, Gad Cotter, Howard C. Dittrich, Paul DeLucca, George A. Mansoor, Daniel M. Bloomfield, Piotr Ponikowski, et al. “Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function.” J Card Fail 16, no. 1 (January 2010): 25–35. https://doi.org/10.1016/j.cardfail.2009.10.025.

O’Connor, Christopher, and Mona Fiuzat. “Antidepressant Use, Depression, and Poor Cardiovascular Outcomes: The Chicken or the Egg?: Comment on "Antidepressant Use and Risk of Incident Cardiovascular Morbidity and Mortality Among Postmenopausal Women in the Women's Health Initiative Study".” Arch Intern Med 169, no. 22 (December 14, 2009): 2140–41. https://doi.org/10.1001/archinternmed.2009.437.

Curtis, Anne B., Clyde W. Yancy, Nancy M. Albert, Wendy Gattis Stough, Mihai Gheorghiade, J Thomas Heywood, Mark L. McBride, et al. “Cardiac resynchronization therapy utilization for heart failure: findings from IMPROVE HF.” Am Heart J 158, no. 6 (December 2009): 956–64. https://doi.org/10.1016/j.ahj.2009.10.011.

Mehra, Mandeep R., Clyde W. Yancy, Nancy M. Albert, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, J Thomas Heywood, et al. “Evidence of clinical practice heterogeneity in the use of implantable cardioverter-defibrillators in heart failure and post-myocardial infarction left ventricular dysfunction: Findings from IMPROVE HF.” Heart Rhythm 6, no. 12 (December 2009): 1727–34. https://doi.org/10.1016/j.hrthm.2009.08.022.

Massie, B. M., S. E. Ammon, J. F. Collins, W. F. Krol, P. W. Armstrong, J. G. F. Cleland, M. Ezekowitz, et al. “Response to letter regarding article, randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: The warfarin and antiplatelet therapy in chronic heart failure (WATCH) trial.” Circulation 120, no. 20 (November 1, 2009). https://doi.org/10.1161/CIRCULATIONAHA.109.884650.

O’Connor, Constance M., Kathleen M. Gilmour, Robert Arlinghaus, Glen Van Der Kraak, and Steven J. Cooke. “Stress and parental care in a wild Teleost fish: insights from exogenous supraphysiological cortisol implants.” Physiol Biochem Zool 82, no. 6 (November 2009): 709–19. https://doi.org/10.1086/605914.

Atchley, Allen E., Dalane W. Kitzman, David J. Whellan, Ami E. Iskandrian, Stephen J. Ellis, Robert A. Pagnanelli, Andrew Kao, et al. “Myocardial perfusion, function, and dyssynchrony in patients with heart failure: baseline results from the single-photon emission computed tomography imaging ancillary study of the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION) Trial.” Am Heart J 158, no. 4 Suppl (October 2009): S53–63. https://doi.org/10.1016/j.ahj.2009.07.009.

Felker, G Michael, David Whellan, William E. Kraus, Robert Clare, Faiez Zannad, Mark Donahue, Kirkwood Adams, et al. “N-terminal pro-brain natriuretic peptide and exercise capacity in chronic heart failure: data from the Heart Failure and a Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) study.” Am Heart J 158, no. 4 Suppl (October 2009): S37–44. https://doi.org/10.1016/j.ahj.2009.07.011.

O’Connor, Christopher M., David J. Whellan, and David J. HF-ACTION Investigators. “Understanding heart failure through the HF-ACTION baseline characteristics.” Am Heart J 158, no. 4 Suppl (October 2009): S1–5. https://doi.org/10.1016/j.ahj.2009.07.013.

Trivedi, Ranak B., James A. Blumenthal, Christopher O’Connor, Kirkwood Adams, Alan Hinderliter, Carla Dupree, Kristy Johnson, and Andrew Sherwood. “Coping styles in heart failure patients with depressive symptoms.” J Psychosom Res 67, no. 4 (October 2009): 339–46. https://doi.org/10.1016/j.jpsychores.2009.05.014.

Weatherley, Beth Davison, Olga Milo-Cotter, G Michael Felker, Nir Uriel, Edo Kaluski, Zvi Vered, Christopher M. O’Connor, Kirkwood F. Adams, and Gad Cotter. “Early worsening heart failure in patients admitted with acute heart failure--a new outcome measure associated with long-term prognosis?” Fundam Clin Pharmacol 23, no. 5 (October 2009): 633–39. https://doi.org/10.1111/j.1472-8206.2009.00697.x.

Whellan, David J., Stephen J. Ellis, William E. Kraus, Katie Hawthorne, Ileana L. Piña, Steven J. Keteyian, Dalane W. Kitzman, Lawton Cooper, Kerry Lee, and Christopher M. O’Connor. “Method for establishing authorship in a multicenter clinical trial.” Ann Intern Med 151, no. 6 (September 15, 2009): 414–20. https://doi.org/10.7326/0003-4819-151-6-200909150-00006.

Felker, G Michael, Vic Hasselblad, Adrian F. Hernandez, and Christopher M. O’Connor. “Biomarker-guided therapy in chronic heart failure: a meta-analysis of randomized controlled trials.” Am Heart J 158, no. 3 (September 2009): 422–30. https://doi.org/10.1016/j.ahj.2009.06.018.

McMurray, John J. V., Inder S. Anand, Rafael Diaz, Aldo P. Maggioni, Christopher O’Connor, Marc A. Pfeffer, Krishna R. Polu, et al. “Design of the Reduction of Events with Darbepoetin alfa in Heart Failure (RED-HF): a Phase III, anaemia correction, morbidity-mortality trial.” Eur J Heart Fail 11, no. 8 (August 2009): 795–801. https://doi.org/10.1093/eurjhf/hfp098.

Fiuzat, Mona, G Michael Felker, Mark P. Donahue, and Christopher M. O’Connor. “Using genetic information to select treatment for patients with heart failure: has the time come?” Per Med 6, no. 4 (July 2009): 385–92. https://doi.org/10.2217/pme.09.19.

Fonarow, Gregg C., William T. Abraham, Nancy M. Albert, Wendy Gattis Stough, Mihai Gheorghiade, Barry H. Greenberg, Christopher M. O’Connor, et al. “Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF).” Am J Cardiol 104, no. 1 (July 1, 2009): 107–15. https://doi.org/10.1016/j.amjcard.2009.02.057.

Allen, Larry A., Adrian F. Hernandez, Christopher M. O’Connor, and G Michael Felker. “End points for clinical trials in acute heart failure syndromes.” J Am Coll Cardiol 53, no. 24 (June 16, 2009): 2248–58. https://doi.org/10.1016/j.jacc.2008.12.079.

Flaherty, James D., Joseph S. Rossi, Gregg C. Fonarow, Eduardo Nunez, Wendy Gattis Stough, William T. Abraham, Nancy M. Albert, et al. “Influence of coronary angiography on the utilization of therapies in patients with acute heart failure syndromes: findings from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).” Am Heart J 157, no. 6 (June 2009): 1018–25. https://doi.org/10.1016/j.ahj.2009.03.011.

Gheorghiade, Mihai, Kirkwood F. Adams, John G. F. Cleland, Gad Cotter, G Michael Felker, Gerasimos S. Filippatos, Gregg C. Fonarow, et al. “Phase III clinical trial end points in acute heart failure syndromes: a virtual roundtable with the Acute Heart Failure Syndromes International Working Group.” Am Heart J 157, no. 6 (June 2009): 957–70. https://doi.org/10.1016/j.ahj.2009.04.010.

Adams, Kirkwood F., James H. Patterson, Ron M. Oren, Mandeep R. Mehra, Christopher M. O’Connor, Ileana L. Piña, Alan B. Miller, et al. “Prospective assessment of the occurrence of anemia in patients with heart failure: results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry.” Am Heart J 157, no. 5 (May 2009): 926–32. https://doi.org/10.1016/j.ahj.2009.01.012.

Gottlieb, Stephen S., Willem J. Kop, Stephen J. Ellis, Philip Binkley, Jonathan Howlett, Christopher O’Connor, James A. Blumenthal, et al. “Relation of depression to severity of illness in heart failure (from Heart Failure And a Controlled Trial Investigating Outcomes of Exercise Training [HF-ACTION]).” Am J Cardiol 103, no. 9 (May 1, 2009): 1285–89. https://doi.org/10.1016/j.amjcard.2009.01.025.

Piccini, Jonathan P., Jeffrey S. Berger, and Christopher M. O’Connor. “Amiodarone for the prevention of sudden cardiac death: a meta-analysis of randomized controlled trials.” Eur Heart J 30, no. 10 (May 2009): 1245–53. https://doi.org/10.1093/eurheartj/ehp100.

Jones, Robert H., Eric J. Velazquez, Robert E. Michler, George Sopko, Jae K. Oh, Christopher M. O’Connor, James A. Hill, et al. “Coronary bypass surgery with or without surgical ventricular reconstruction.” N Engl J Med 360, no. 17 (April 23, 2009): 1705–17. https://doi.org/10.1056/NEJMoa0900559.

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Sherwood, Andrew, James A. Blumenthal, Ranak Trivedi, Kristy S. Johnson, Christopher M. O’Connor, Kirkwood F. Adams, Carla Sueta Dupree, et al. “Relationship of depression to death or hospitalization in patients with heart failure.” Arch Intern Med 167, no. 4 (February 26, 2007): 367–73. https://doi.org/10.1001/archinte.167.4.367.

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Xiong, Glen L., Wei Jiang, Robert Clare, Linda K. Shaw, Peter K. Smith, Kenneth W. Mahaffey, Christopher M. O’Connor, K Ranga R. Krishnan, and L Kristin Newby. “Prognosis of patients taking selective serotonin reuptake inhibitors before coronary artery bypass grafting.” Am J Cardiol 98, no. 1 (July 1, 2006): 42–47. https://doi.org/10.1016/j.amjcard.2006.01.051.

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Cohn, Jay N., Peter E. Carson, Christopher O’Connor, Cristina Opasich, Ileana L. Piña, Marino Scherillo, Gianfranco Sinagra, Lynne Warner-Stevenson, Felix E. Tristani, and Alberto Volpi. “Prognosis and mechanism of death in treated heart failure: data from the placebo arm of Val-HeFT.” Congest Heart Fail 12, no. 3 (May 2006): 127–31. https://doi.org/10.1111/j.1527-5299.2006.05441.x.

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Douglas, Pamela, Robert A. Harrington, Christopher M. O’Connor, James H. Stein, and Matthew R. Wolff. “President's page: New York 1952 to Atlanta 2006: celebrating the cardiovascular community.” J Am Coll Cardiol 47, no. 1 (January 3, 2006): 203–4. https://doi.org/10.1016/j.jacc.2005.11.008.

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Serebruany, Victor L., Alex N. Pokov, Alex I. Malinin, Christopher O’Connor, Deepak L. Bhatt, Jean-Francois Tanguay, David C. Sane, and Charles H. Hennekens. “Valsartan inhibits platelet activity at different doses in mild to moderate hypertensives: Valsartan Inhibits Platelets (VIP) trial.” Am Heart J 151, no. 1 (January 2006): 92–99. https://doi.org/10.1016/j.ahj.2005.03.001.

Carson, Peter, Inder Anand, Christopher O’Connor, Brian Jaski, Jonathan Steinberg, Amy Lwin, JoAnn Lindenfeld, et al. “Mode of death in advanced heart failure: the Comparison of Medical, Pacing, and Defibrillation Therapies in Heart Failure (COMPANION) trial.” J Am Coll Cardiol 46, no. 12 (December 20, 2005): 2329–34. https://doi.org/10.1016/j.jacc.2005.09.016.

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Hernandez, Adrian F., Eric J. Velazquez, Scott D. Solomon, Rakhi Kilaru, Rafael Diaz, Christopher M. O’Connor, George Ertl, et al. “Left ventricular assessment in myocardial infarction: the VALIANT registry.” Arch Intern Med 165, no. 18 (October 10, 2005): 2162–69. https://doi.org/10.1001/archinte.165.18.2162.

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Shah, Monica R., Vic Hasselblad, Lynne W. Stevenson, Cynthia Binanay, Christopher M. O’Connor, George Sopko, and Robert M. Califf. “Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials.” Jama 294, no. 13 (October 5, 2005): 1664–70. https://doi.org/10.1001/jama.294.13.1664.

Thomas, Kevin L., Mark A. East, Eric J. Velazquez, Robert H. Tuttle, Linda K. Shaw, Christopher M. O’Connor, and Eric D. Peterson. “Outcomes by race and etiology of patients with left ventricular systolic dysfunction.” Am J Cardiol 96, no. 7 (October 1, 2005): 956–63. https://doi.org/10.1016/j.amjcard.2005.07.002.

Gheorghiade, Mihai, Wendy Gattis Stough, Kirkwood F. Adams, Allan S. Jaffe, Victor Hasselblad, and Christopher M. O’Connor. “The Pilot Randomized Study of Nesiritide Versus Dobutamine in Heart Failure (PRESERVD-HF).” Am J Cardiol 96, no. 6A (September 19, 2005): 18G-25G. https://doi.org/10.1016/j.amjcard.2005.07.017.

Stough, Wendy Gattis, Christopher M. O’Connor, and Mihai Gheorghiade. “Overview of current noninodilator therapies for acute heart failure syndromes.” Am J Cardiol 96, no. 6A (September 19, 2005): 41G-46G. https://doi.org/10.1016/j.amjcard.2005.07.020.

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Schroder, Jacob N., Matthew L. Williams, Jonathan A. Hata, Lawrence H. Muhlbaier, Madhav Swaminathan, Joseph P. Mathew, Donald D. Glower, Christopher M. O’Connor, Peter K. Smith, and Carmelo A. Milano. “Impact of mitral valve regurgitation evaluated by intraoperative transesophageal echocardiography on long-term outcomes after coronary artery bypass grafting.” Circulation 112, no. 9 Suppl (August 30, 2005): I293–98. https://doi.org/10.1161/CIRCULATIONAHA.104.523472.

Adams, Kirkwood F., J Herbert Patterson, Wendy A. Gattis, Christopher M. O’Connor, Craig R. Lee, Todd A. Schwartz, and Mihai Gheorghiade. “Relationship of serum digoxin concentration to mortality and morbidity in women in the digitalis investigation group trial: a retrospective analysis.” J Am Coll Cardiol 46, no. 3 (August 2, 2005): 497–504. https://doi.org/10.1016/j.jacc.2005.02.091.

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Jiang, Wei, Alexander Glassman, Ranga Krishnan, Christopher M. O’Connor, and Robert M. Califf. “Depression and ischemic heart disease: what have we learned so far and what must we do in the future?” Am Heart J 150, no. 1 (July 2005): 54–78. https://doi.org/10.1016/j.ahj.2005.04.012.

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Serebruany, Victor L., Raymond F. Suckow, Thomas B. Cooper, Christopher M. O’Connor, Alex I. Malinin, K Ranga R. Krishnan, Louis T. van Zyl, Vladimir Lekht, Alexander H. Glassman, and Alexander H. Sertraline Antidepressant Heart Attack Randomized Trial. “Relationship between release of platelet/endothelial biomarkers and plasma levels of sertraline and N-desmethylsertraline in acute coronary syndrome patients receiving SSRI treatment for depression.” Am J Psychiatry 162, no. 6 (June 2005): 1165–70. https://doi.org/10.1176/appi.ajp.162.6.1165.

Klein, Liviu, Christopher M. O’Connor, Jeffrey D. Leimberger, Wendy Gattis-Stough, Ileana L. Piña, G Michael Felker, Kirkwood F. Adams, Robert M. Califf, Mihai Gheorghiade, and Mihai OPTIME-CHF Investigators. “Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study.” Circulation 111, no. 19 (May 17, 2005): 2454–60. https://doi.org/10.1161/01.CIR.0000165065.82609.3D.

Kovacic, Jason C. “Further aspects of anemia, heart failure, and erythropoietin.” J Am Coll Cardiol 45, no. 9 (May 3, 2005): 1549–50. https://doi.org/10.1016/j.jacc.2005.02.023.

Joynt, Karen E., and Christopher M. O’Connor. “Lessons from SADHART, ENRICHD, and other trials.” Psychosom Med 67 Suppl 1 (May 2005): S63–66. https://doi.org/10.1097/01.psy.0000163454.25036.fc.

Al-Khatib, Sana M., Kevin J. Anstrom, Eric L. Eisenstein, Eric D. Peterson, James G. Jollis, Daniel B. Mark, Yun Li, Christopher M. O’Connor, Linda K. Shaw, and Robert M. Califf. “Clinical and economic implications of the Multicenter Automatic Defibrillator Implantation Trial-II.” Ann Intern Med 142, no. 8 (April 19, 2005): 593–600. https://doi.org/10.7326/0003-4819-142-8-200504190-00007.

O’Connor, Christopher M., Wendy Gattis Stough, Dianne S. Gallup, Vic Hasselblad, and Mihai Gheorghiade. “Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry.” J Card Fail 11, no. 3 (April 2005): 200–205. https://doi.org/10.1016/j.cardfail.2004.08.160.

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O’Connor, Christopher M., Alexander H. Glassman, and David J. Harrison. “Pharmacoeconomic analysis of sertraline treatment of depression in patients with unstable angina or a recent myocardial infarction.” J Clin Psychiatry 66, no. 3 (March 2005): 346–52. https://doi.org/10.4088/jcp.v66n0311.

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Felker, G Michael, Jeffrey D. Leimberger, Robert M. Califf, Michael S. Cuffe, Barry M. Massie, Kirkwood F. Adams, Mihai Gheorghiade, and Christopher M. O’Connor. “Risk stratification after hospitalization for decompensated heart failure.” J Card Fail 10, no. 6 (December 2004): 460–66. https://doi.org/10.1016/j.cardfail.2004.02.011.

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Velazquez, Eric J., Gary S. Francis, Paul W. Armstrong, Phillip E. Aylward, Rafael Diaz, Christopher M. O’Connor, Harvey D. White, et al. “An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry.” Eur Heart J 25, no. 21 (November 2004): 1911–19. https://doi.org/10.1016/j.ehj.2004.08.006.

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Hernandez, Adrian F., David J. Whellan, Sharon Stroud, Jie Lena Sun, Christopher M. O’Connor, and James G. Jollis. “Outcomes in heart failure patients after major noncardiac surgery.” J Am Coll Cardiol 44, no. 7 (October 6, 2004): 1446–53. https://doi.org/10.1016/j.jacc.2004.06.059.

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Al-Khatib, Sana M., Linda K. Shaw, Kerry L. Lee, Christopher O’Connor, and Robert M. Califf. “Is rhythm control superior to rate control in patients with atrial fibrillation and congestive heart failure?” Am J Cardiol 94, no. 6 (September 15, 2004): 797–800. https://doi.org/10.1016/j.amjcard.2004.06.009.

Hernandez, Adrian F., L Kristin Newby, and Christopher M. O’Connor. “Preoperative evaluation for major noncardiac surgery: focusing on heart failure.” Arch Intern Med 164, no. 16 (September 13, 2004): 1729–36. https://doi.org/10.1001/archinte.164.16.1729.

Felker, G Michael, Kirkwood F. Adams, Wendy A. Gattis, and Christopher M. O’Connor. “Anemia as a risk factor and therapeutic target in heart failure.” J Am Coll Cardiol 44, no. 5 (September 1, 2004): 959–66. https://doi.org/10.1016/j.jacc.2004.05.070.

Harrington, Robert A., Richard C. Becker, Michael Ezekowitz, Thomas W. Meade, Christopher M. O’Connor, David A. Vorchheimer, and Gordon H. Guyatt. “Antithrombotic therapy for coronary artery disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.” Chest 126, no. 3 Suppl (September 2004): 513S-548S. https://doi.org/10.1378/chest.126.3_suppl.513S.

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Hedayati, S Susan, Wei Jiang, Christopher M. O’Connor, Maragatha Kuchibhatla, K Ranga Krishnan, Michael S. Cuffe, Michael A. Blazing, and Lynda A. Szczech. “The association between depression and chronic kidney disease and mortality among patients hospitalized with congestive heart failure.” Am J Kidney Dis 44, no. 2 (August 2004): 207–15. https://doi.org/10.1053/j.ajkd.2004.04.025.

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East, Mark A., Eric D. Peterson, Linda K. Shaw, Wendy A. Gattis, and Christopher M. O’Connor. “Racial differences in the outcomes of patients with diastolic heart failure.” Am Heart J 148, no. 1 (July 2004): 151–56. https://doi.org/10.1016/j.ahj.2004.01.017.

Fonarow, Gregg C., William T. Abraham, Nancy M. Albert, Wendy A. Gattis, Mihai Gheorghiade, Barry Greenberg, Chris M. O’Connor, Clyde W. Yancy, and James Young. “Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF): rationale and design.” Am Heart J 148, no. 1 (July 2004): 43–51. https://doi.org/10.1016/j.ahj.2004.03.004.

Gattis, Wendy A., Christopher M. O’Connor, Vic Hasselblad, Kirkwood F. Adams, Isaac Kobrin, and Mihai Gheorghiade. “Usefulness of an elevated troponin-I in predicting clinical events in patients admitted with acute heart failure and acute coronary syndrome (from the RITZ-4 trial).” Am J Cardiol 93, no. 11 (June 1, 2004): 1436-A10. https://doi.org/10.1016/j.amjcard.2004.02.051.

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Gattis, Wendy A., and Christopher M. O’Connor. “Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure.” Am J Cardiol 93, no. 9A (May 6, 2004): 74B-76B. https://doi.org/10.1016/j.amjcard.2004.01.019.

Gattis, Wendy A., Christopher M. O’Connor, Dianne S. Gallup, Vic Hasselblad, Mihai Gheorghiade, and Mihai IMPACT-HF Investigators and Coordinators. “Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure: results of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy in Heart Failure (IMPACT-HF) trial.” J Am Coll Cardiol 43, no. 9 (May 5, 2004): 1534–41. https://doi.org/10.1016/j.jacc.2003.12.040.

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Serebruany, Victor L., Alex I. Malinin, David R. Lowry, David C. Sane, Randy L. Webb, Sidney O. Gottlieb, Christopher M. O’Connor, and Charles H. Hennekens. “Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits.” J Cardiovasc Pharmacol 43, no. 5 (May 2004): 677–84. https://doi.org/10.1097/00005344-200405000-00010.

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Klein, Liviu, Wendy A. Gattis, Francesco Borrello, Edwin Wu, Christopher M. O’Connor, and Mihai Gheorghiade. “Effects of amino acid supplementation on left ventricular remodeling in patients with chronic heart failure with decreased systolic function and diabetes mellitus: rationale and design of a magnetic resonance imaging study.” Am J Cardiol 93, no. 8A (April 22, 2004): 44A-46A. https://doi.org/10.1016/j.amjcard.2003.11.010.

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Bourque, Jamieson M., Eric J. Velazquez, Salvador Borges-Neto, Linda K. Shaw, David J. Whellan, and Christopher M. O’connor. “Clinical characteristics and referral pattern of patients with left ventricular dysfunction and significant coronary artery disease undergoing radionuclide imaging.” J Nucl Cardiol 11, no. 2 (March 2004): 118–25. https://doi.org/10.1016/j.nuclcard.2003.09.005.

Hudson, Michael P., Christopher M. O’Connor, Wendy A. Gattis, Gudaye Tasissa, Vic Hasselblad, Cathy M. Holleman, Laura H. Gaulden, Frank Sedor, and E Magnus Ohman. “Implications of elevated cardiac troponin T in ambulatory patients with heart failure: a prospective analysis.” Am Heart J 147, no. 3 (March 2004): 546–52. https://doi.org/10.1016/j.ahj.2003.10.014.

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Whellan, David J., Christopher M. O’Connor, and Ileana Pina. “Training trials in heart failure: time to exercise restraint?” Am Heart J 147, no. 2 (February 2004): 190–92. https://doi.org/10.1016/j.ahj.2003.09.008.

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Swenson, J Robert, Christopher M. O’Connor, David Barton, Louis T. Van Zyl, Karl Swedberg, Leslie M. Forman, Michael Gaffney, Alexander H. Glassman, and Alexander H. Sertraline Antidepressant Heart Attack Randomized Trial (SADHART) Group. “Influence of depression and effect of treatment with sertraline on quality of life after hospitalization for acute coronary syndrome.” Am J Cardiol 92, no. 11 (December 1, 2003): 1271–76. https://doi.org/10.1016/j.amjcard.2003.08.006.

Bourque, Jamieson Macdonald, Vic Hasselblad, Eric J. Velazquez, Salvador Borges-Neto, and Christopher M. O’connor. “Revascularization in patients with coronary artery disease, left ventricular dysfunction, and viability: a meta-analysis.” Am Heart J 146, no. 4 (October 2003): 621–27. https://doi.org/10.1016/S0002-8703(03)00428-9.

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O’Connor, Christopher M., Michael W. Dunne, Marc A. Pfeffer, Joseph B. Muhlestein, Louis Yao, Sandeep Gupta, Rebecca J. Benner, Marian R. Fisher, Thomas D. Cook, and Thomas D. Investigators in the WIZARD Study. “Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial.” Jama 290, no. 11 (September 17, 2003): 1459–66. https://doi.org/10.1001/jama.290.11.1459.

Trichon, Benjamin H., Donald D. Glower, Linda K. Shaw, Christopher H. Cabell, Kevin J. Anstrom, G Michael Felker, and Christopher M. O’Connor. “Survival after coronary revascularization, with and without mitral valve surgery, in patients with ischemic mitral regurgitation.” Circulation 108 Suppl 1 (September 9, 2003): II103–10. https://doi.org/10.1161/01.cir.0000087656.10829.df.

Felker, G Michael, Wendy A. Gattis, Jeffrey D. Leimberger, Kirkwood F. Adams, Michael S. Cuffe, Mihai Gheorghiade, and Christopher M. O’Connor. “Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure.” Am J Cardiol 92, no. 5 (September 1, 2003): 625–28. https://doi.org/10.1016/s0002-9149(03)00740-9.

Serebruany, Victor L., Alexander H. Glassman, Alex I. Malinin, David C. Sane, Mitchell S. Finkel, Ranga R. Krishnan, Dan Atar, Vladimir Lekht, and Christopher M. O’Connor. “Enhanced platelet/endothelial activation in depressed patients with acute coronary syndromes: evidence from recent clinical trials.” Blood Coagul Fibrinolysis 14, no. 6 (September 2003): 563–67. https://doi.org/10.1097/00001721-200309000-00008.

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Hernandez, Adrian F., and Christopher M. O’Connor. “Sparing a little may save a lot: lessons from the Studies of Left Ventricular Dysfunction (SOLVD).” J Am Coll Cardiol 42, no. 4 (August 20, 2003): 709–11. https://doi.org/10.1016/s0735-1097(03)00766-6.

Joynt, Karen E., David J. Whellan, and Christopher M. O’Connor. “Depression and cardiovascular disease: mechanisms of interaction.” Biol Psychiatry 54, no. 3 (August 1, 2003): 248–61. https://doi.org/10.1016/s0006-3223(03)00568-7.

Serebruany, V. L., A. H. Glassman, A. I. Malinin, D. Atar, D. C. Sane, B. R. Oshrine, J. J. Ferguson, and C. M. O’Connor. “Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin.” Eur J Heart Fail 5, no. 4 (August 2003): 517–21. https://doi.org/10.1016/s1388-9842(03)00005-9.

Jiang, Wei, Michael A. Babyak, Alan Rozanski, Andrew Sherwood, Christopher M. O’Connor, Robert A. Waugh, R Edward Coleman, Michael W. Hanson, James J. Morris, and James A. Blumenthal. “Depression and increased myocardial ischemic activity in patients with ischemic heart disease.” Am Heart J 146, no. 1 (July 2003): 55–61. https://doi.org/10.1016/S0002-8703(03)00152-2.

Lee, Craig R., Michael L. Watkins, J Herbert Patterson, Wendy Gattis, Christopher M. O’connor, Mihai Gheorghiade, and Kirkwood F. Adams. “Vasopressin: a new target for the treatment of heart failure.” Am Heart J 146, no. 1 (July 2003): 9–18. https://doi.org/10.1016/S0002-8703(02)94708-3.

Serebruany, Victor L., Alex I. Malinin, Christopher M. O’connor, Paul A. Gurbel, and Paul A. Roxifiban Oral Compound Kinetics Evaluation Trial-I Platelet Substudy. “Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy).” Am Heart J 146, no. 1 (July 2003): 91–98. https://doi.org/10.1016/S0002-8703(03)00186-8.

Gurbel, Paul A., Kevin P. Bliden, Bonnie L. Hiatt, and Christopher M. O’Connor. “Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.” Circulation 107, no. 23 (June 17, 2003): 2908–13. https://doi.org/10.1161/01.CIR.0000072771.11429.83.

Klein, Liviu, Christopher M. O’Connor, Wendy A. Gattis, Manuela Zampino, Leonardo de Luca, Antonio Vitarelli, Francesco Fedele, and Mihai Gheorghiade. “Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations.” Am J Cardiol 91, no. 9A (May 8, 2003): 18F-40F. https://doi.org/10.1016/s0002-9149(02)03336-2.

O’Connor, Christopher M., Wendy A. Gattis, Kirkwood F. Adams, Vic Hasselblad, Bleakley Chandler, Aline Frey, Isaac Kobrin, et al. “Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4).” J Am Coll Cardiol 41, no. 9 (May 7, 2003): 1452–57. https://doi.org/10.1016/s0735-1097(03)00194-3.

Bourque, Jamieson MacDonald, Eric J. Velazquez, Salvador Borges-Neto, Linda K. Shaw, David J. Whellan, and Christopher M. O’Connor. “Radionuclide viability testing: should it affect treatment strategy in patients with cardiomyopathy and significant coronary artery disease?” Am Heart J 145, no. 5 (May 2003): 758–67. https://doi.org/10.1016/S0002-8703(02)94818-0.

Felker, G Michael, Raymond L. Benza, A Bleakley Chandler, Jeffrey D. Leimberger, Michael S. Cuffe, Robert M. Califf, Mihai Gheorghiade, Christopher M. O’Connor, and Christopher M. OPTIME-CHF Investigators. “Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study.” J Am Coll Cardiol 41, no. 6 (March 19, 2003): 997–1003. https://doi.org/10.1016/s0735-1097(02)02968-6.

Malinin, Alex I., Christopher M. O’Connor, Alec I. Dzhanashvili, David C. Sane, and Victor L. Serebruany. “Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel?” Am Heart J 145, no. 3 (March 2003): 397–403. https://doi.org/10.1067/mhj.2003.163.

Trichon, Benjamin H., G Michael Felker, Linda K. Shaw, Christopher H. Cabell, and Christopher M. O’Connor. “Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure.” Am J Cardiol 91, no. 5 (March 1, 2003): 538–43. https://doi.org/10.1016/s0002-9149(02)03301-5.

Felker, G Michael, Kirkwood F. Adams, Marvin A. Konstam, Christopher M. O’Connor, and Mihai Gheorghiade. “The problem of decompensated heart failure: nomenclature, classification, and risk stratification.” Am Heart J 145, no. 2 Suppl (February 2003): S18–25. https://doi.org/10.1067/mhj.2003.150.

Felker, G Michael, and Christopher M. O’connor. “A bridge for the 21st century in heart transplantation?” Am Heart J 145, no. 2 (February 2003): 198–99. https://doi.org/10.1067/mhj.2003.51.

Gheorghiade, M., W. A. Gattis, C. M. O’Connor, and K. F. Adams. “The management of decompensated heart failure resulting in hospitalization: Proceedings from an expert meeting to review current concepts and to define future directions - Introduction.” American Heart Journal 145, no. 2 SUPPL. (February 1, 2003). https://doi.org/10.1067/mhj.2003.148.

Gheorghiade, Mihai, Kirkwood F. Adams, Wendy A. Gattis, John R. Teerlink, Cesare Orlandi, and Christopher M. O’Connor. “Surrogate end points in heart failure trials.” Am Heart J 145, no. 2 Suppl (February 2003): S67–70. https://doi.org/10.1067/mhj.2003.159.

Gheorghiade, Mihai, Wendy A. Gattis, Alejandro Barbagelata, Kirkwood F. Adams, Uri Elkayam, Cesare Orlandi, Christopher M. O’Connor, and Christopher M. Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Congestive Heart Failure Investigators. “Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure.” Am Heart J 145, no. 2 Suppl (February 2003): S51–54. https://doi.org/10.1067/mhj.2003.154.

Gheorghiade, Mihai, Wendy A. Gattis, Kirkwood F. Adams, Alan S. Jaffe, Christopher M. O’Connor, Christopher M. Pilot Randomized Study of Nesiritide versus Dobutamine in Heart Failure, and Christopher M. Duke University Cooperative Cardiovascular Studies Investigators. “Rationale and design of the pilot randomized study of nesiritide versus dobutamine in heart failure (PRESERVD-HF).” Am Heart J 145, no. 2 Suppl (February 2003): S55–57. https://doi.org/10.1067/mhj.2003.155.

Gheorghiade, Mihai, Wendy A. Gattis, Mary Ann Lukas, Christopher M. O’Connor, and Christopher M. Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure Investigators. “Rationale and design of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) study.” Am Heart J 145, no. 2 Suppl (February 2003): S60–61. https://doi.org/10.1067/mhj.2003.157.

O’Connor, Christopher M., Wendy A. Gattis, John R. Teerlink, Kirkwood F. Adams, and Mihai Gheorghiade. “Design considerations and proposed template for clinical trials in hospitalized patients with decompensated chronic heart failure.” Am Heart J 145, no. 2 Suppl (February 2003): S47–50. https://doi.org/10.1067/mhj.2003.153.

O’Connor, Christopher M., Wendy A. Gattis, Kirkwood F. Adams, Monica R. Shah, Aline Frey, Mihai Gheorghiade, and Mihai Randomized Intravenous Tezosentan Study Investigators. “Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the fourth Randomized Intravenous Tezosentan Study (RITZ-4).” Am Heart J 145, no. 2 Suppl (February 2003): S58–59. https://doi.org/10.1067/mhj.2003.156.

Zampino, Manuela, Christopher M. O’Connor, Wendy A. Gattis, Kirkwood F. Adams, and Mihai Gheorghiade. “Concomitant use of a positive inotropic agent to create a bridge to the successful initiation of beta-blocker therapy in patients with heart failure: a proposal for a trial.” Am Heart J 145, no. 2 Suppl (February 2003): S62–66. https://doi.org/10.1067/mhj.2003.158.

Gattis, Wendy A., Christopher M. O’Connor, Jeffrey D. Leimberger, G Michael Felker, Kirkwood F. Adams, and Mihai Gheorghiade. “Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure.” Am J Cardiol 91, no. 2 (January 15, 2003): 169–74. https://doi.org/10.1016/s0002-9149(02)03104-1.

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Bourque, J. M. D., E. J. Velazquez, S. Borges-Neto, V. Hasselblad, and C. M. O’Connor. “A reappraisal of myocardial viability testing in patients with coronary artery disease and left ventricular dysfunction: Can meta-analysis be trusted?” Heartdrug 2, no. 4 (December 1, 2002): 204–5. https://doi.org/10.1159/000065943.

Gheorghiade, M., W. A. Gattis, M. A. Lukas, and C. M. O’Connor. “Rationale and design of the initiation management predischarge: Process for assessment of carvedilol therapy for heart failure (IMPACT-HF) study.” Heartdrug 2, no. 4 (December 1, 2002): 164–66. https://doi.org/10.1159/000065939.

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O’Connor, Christopher M., Wendy A. Gattis, Kirkwood F. Adams, Monica R. Shah, Isaac Kobrin, Aline Frey, and Mihai Gheorghiade. “Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the Randomized Intravenous Tezosentan study (RITZ-4).” Am Heart J 144, no. 4 (October 2002): 583–88. https://doi.org/10.1016/s0002-8703(02)00127-8.

Carney, R. M., J. A. Blumenthal, P. K. Stein, L. Watkins, D. Catellier, L. F. Berkman, S. M. Czajkowski, C. O’Connor, P. H. Stone, and K. E. Freedland. “Depression, heart rate variability, and acute myocardial infarction.” Revista De Psiquiatria Clinica 29, no. 3 (September 14, 2002): 158–59.

Trichon, Benjamin H., and Christopher M. O’Connor. “Secondary mitral and tricuspid regurgitation accompanying left ventricular systolic dysfunction: is it important, and how is it treated?” Am Heart J 144, no. 3 (September 2002): 373–76. https://doi.org/10.1067/mhj.2002.123576.

Glassman, Alexander H., Christopher M. O’Connor, Robert M. Califf, Karl Swedberg, Peter Schwartz, J Thomas Bigger, K Ranga Rama Krishnan, et al. “Sertraline treatment of major depression in patients with acute MI or unstable angina.” Jama 288, no. 6 (August 14, 2002): 701–9. https://doi.org/10.1001/jama.288.6.701.

Gurbel, Paul A., Alex I. Malinin, Kevin P. Callahan, Victor L. Serebruany, and Christopher M. O’Connor. “Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation.” Am J Cardiol 90, no. 3 (August 1, 2002): 312–15. https://doi.org/10.1016/s0002-9149(02)02471-2.

Serebruany, V., M. McKenzie, A. Meister, S. Fuzaylov, P. Gurbel, D. Atar, W. Gattis, and C. O’Connor. “Whole blood impedance aggregometry for the assessment of platelet function in patients with congestive heart failure (EPCOT Trial).” Eur J Heart Fail 4, no. 4 (August 2002): 461–67. https://doi.org/10.1016/s1388-9842(02)00026-0.

O’Connor, Christopher M., Eric J. Velazquez, Laura H. Gardner, Peter K. Smith, Mark F. Newman, Kevin P. Landolfo, Kerry L. Lee, Robert M. Califf, and Robert H. Jones. “Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank).” Am J Cardiol 90, no. 2 (July 15, 2002): 101–7. https://doi.org/10.1016/s0002-9149(02)02429-3.

Neuberg, Gerald W., Alan B. Miller, Chris M. O’Connor, Robert N. Belkin, Peter E. Carson, Anne B. Cropp, David J. Frid, et al. “Diuretic resistance predicts mortality in patients with advanced heart failure.” Am Heart J 144, no. 1 (July 2002): 31–38. https://doi.org/10.1067/mhj.2002.123144.

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Gottlieb, Stephen S., William Abraham, Javed Butler, Daniel E. Forman, Evan Loh, Barry M. Massie, Christopher M. O’connor, et al. “The prognostic importance of different definitions of worsening renal function in congestive heart failure.” J Card Fail 8, no. 3 (June 2002): 136–41. https://doi.org/10.1054/jcaf.2002.125289.

Gurbel, Paul A., Wendy A. Gattis, Sergey F. Fuzaylov, Laura Gaulden, Vic Hasselblad, Victor L. Serebruany, and Christopher M. O’Connor. “Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?” Am Heart J 143, no. 6 (June 2002): 1068–75. https://doi.org/10.1067/mhj.2002.121261.

Shah, Monica R., Vic Hasselblad, Sandra S. Stinnett, Judith M. Kramer, Steven Grossman, Mihai Gheorghiade, Kirkwood F. Adams, Karl Swedberg, Robert M. Califf, and Christopher M. O’Connor. “Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure.” Eur J Heart Fail 4, no. 3 (June 2002): 297–304. https://doi.org/10.1016/s1388-9842(01)00202-1.

Cuffe, Michael S., Robert M. Califf, Kirkwood F. Adams, Raymond Benza, Robert Bourge, Wilson S. Colucci, Barry M. Massie, et al. “Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial.” Jama 287, no. 12 (March 27, 2002): 1541–47. https://doi.org/10.1001/jama.287.12.1541.

Jiang, Wei, Vic Hasselblad, Ranga R. Krishnan, and Christopher M. O’Connor. “Patients with CHF and depression have greater risk of mortality and morbidity than patients without depression.” J Am Coll Cardiol 39, no. 5 (March 6, 2002): 919–21. https://doi.org/10.1016/s0735-1097(02)01694-7.

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Felker, G Michael, Linda K. Shaw, and Christopher M. O’Connor. “A standardized definition of ischemic cardiomyopathy for use in clinical research.” J Am Coll Cardiol 39, no. 2 (January 16, 2002): 210–18. https://doi.org/10.1016/s0735-1097(01)01738-7.

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Gattis, Wendy A., Christopher M. O’Connor, and Mihai Gheorghiade. “The Initiation Management Predischarge Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) Study: design and implications.” Rev Cardiovasc Med 3 Suppl 3 (2002): S48–54.

Gheorghiade, Mihai, Wendy A. Gattis, and Christopher M. O’Connor. “Treatment gaps in the pharmacologic management of heart failure.” Rev Cardiovasc Med 3 Suppl 3 (2002): S11–19.

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Serebruany, Victor L., Marcus E. McKenzie, Andrew F. Meister, Sergey Y. Fuzaylov, Paul A. Gurbel, Dan Atar, Wendy A. Gattis, and Christopher M. O’Connor. “Failure of platelet parameters and biomarkers to correlate platelet function to severity and etiology of heart failure in patients enrolled in the EPCOT trial. With special reference to the Hemodyne hemostatic analyzer. Whole Blood Impedance Aggregometry for the Assessment of Platelet Function in Patients with Congestive Heart Failure.” Pathophysiol Haemost Thromb 32, no. 1 (January 2002): 8–15. https://doi.org/10.1159/000057283.

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Serebruany, V. L., C. J. Davis, A. F. Meister, D. Atar, D. J. Whellan, and C. M. O’Connor. “Biomarkers and exercise training: A possible missing link between physical activity and mortality benefit in patients with heart failure.” Heartdrug 1, no. 2 (December 1, 2001): 110–24. https://doi.org/10.1159/000048946.

Shah, M. R., V. Hasselblad, M. Gheorghiade, K. F. Adams, K. Swedberg, R. M. Califf, and C. M. O’Connor. “Prognostic usefulness of the six-minute walk in patients with advanced congestive heart failure secondary to ischemic or nonischemic cardiomyopathy.” Am J Cardiol 88, no. 9 (November 1, 2001): 987–93. https://doi.org/10.1016/s0002-9149(01)01975-0.

Carney, R. M., J. A. Blumenthal, P. K. Stein, L. Watkins, D. Catellier, L. F. Berkman, S. M. Czajkowski, C. O’Connor, P. H. Stone, and K. E. Freedland. “Depression, heart rate variability, and acute myocardial infarction.” Circulation 104, no. 17 (October 23, 2001): 2024–28. https://doi.org/10.1161/hc4201.097834.

Whellan, D. J., L. Gaulden, W. A. Gattis, B. Granger, S. D. Russell, M. A. Blazing, M. S. Cuffe, and C. M. O’Connor. “The benefit of implementing a heart failure disease management program.” Arch Intern Med 161, no. 18 (October 8, 2001): 2223–28. https://doi.org/10.1001/archinte.161.18.2223.

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Felker, G. M., and C. M. O’Connor. “Inotropic therapy for heart failure: an evidence-based approach.” Am Heart J 142, no. 3 (September 2001): 393–401. https://doi.org/10.1067/mhj.2001.117606.

O’Connor, C. M., W. A. Gattis, A. S. Hellkamp, A. Langer, R. L. Larsen, R. A. Harrington, S. D. Berkowitz, et al. “Comparison of two aspirin doses on ischemic stroke in post-myocardial infarction patients in the warfarin (Coumadin) Aspirin Reinfarction Study (CARS).” Am J Cardiol 88, no. 5 (September 1, 2001): 541–46. https://doi.org/10.1016/s0002-9149(01)01735-0.

Jiang, W., J. Alexander, E. Christopher, M. Kuchibhatla, L. H. Gaulden, M. S. Cuffe, M. A. Blazing, et al. “Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure.” Arch Intern Med 161, no. 15 (August 13, 2001): 1849–56. https://doi.org/10.1001/archinte.161.15.1849.

ENRICHD Investigators, J. A. “Enhancing recovery in coronary heart disease (ENRICHD): baseline characteristics.” Am J Cardiol 88, no. 3 (August 1, 2001): 316–22. https://doi.org/10.1016/s0002-9149(01)01652-6.

Alexander, K. P., L. K. Newby, A. S. Hellkamp, R. A. Harrington, E. D. Peterson, S. Kopecky, A. Langer, et al. “Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up.” J Am Coll Cardiol 38, no. 1 (July 2001): 1–7. https://doi.org/10.1016/s0735-1097(01)01329-8.

Whellan, D. J., L. K. Shaw, B. A. Bart, W. E. Kraus, R. M. Califf, and C. M. O’Connor. “Cardiac rehabilitation and survival in patients with left ventricular systolic dysfunction.” Am Heart J 142, no. 1 (July 2001): 160–66. https://doi.org/10.1067/mhj.2001.115785.

Serebruany, V. L., C. M. O’Connor, and P. A. Gurbel. “Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease.” Am J Cardiol 87, no. 12 (June 15, 2001): 1398–1400. https://doi.org/10.1016/s0002-9149(01)01562-4.

Rosenberg, E. L., P. Ekman, W. Jiang, M. Babyak, R. E. Coleman, M. Hanson, C. O’Connor, R. Waugh, and J. A. Blumenthal. “Linkages between facial expressions of anger and transient myocardial ischemia in men with coronary artery disease.” Emotion 1, no. 2 (June 2001): 107–15. https://doi.org/10.1037/1528-3542.1.2.107.

Shah, M. R., S. S. Stinnett, S. E. McNulty, M. Gheorghiade, F. Zannad, B. Uretsky, K. F. Adams, R. M. Califf, and C. M. O’connor. “Hemodynamics as surrogate end points for survival in advanced heart failure: an analysis from FIRST.” Am Heart J 141, no. 6 (June 2001): 908–14. https://doi.org/10.1067/mhj.2001.115299.

Shah, M. R., V. Hasselblad, S. S. Stinnett, M. Gheorghiade, K. Swedberg, R. M. Califf, and C. M. O’Connor. “Hemodynamic profiles of advanced heart failure: association with clinical characteristics and long-term outcomes.” J Card Fail 7, no. 2 (June 2001): 105–13. https://doi.org/10.1054/jcaf.2001.24131.

Serebruany, V. L., P. A. Gurbel, and C. M. O’Connor. “Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors.” Pharmacol Res 43, no. 5 (May 2001): 453–62. https://doi.org/10.1006/phrs.2001.0817.

Shah, M. R., C. M. O’Connor, G. Sopko, V. Hasselblad, R. M. Califf, and L. W. Stevenson. “Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE): design and rationale.” Am Heart J 141, no. 4 (April 2001): 528–35. https://doi.org/10.1067/mhj.2001.113995.

Gurbel, P. A., C. M. O’Connor, M. R. Dalesandro, and V. L. Serebruany. “Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy.” Am J Cardiol 87, no. 6 (March 15, 2001): 774-A7. https://doi.org/10.1016/s0002-9149(00)01502-2.

Serebruany, V. L., A. B. Alford, A. F. Meister, S. Y. Fuzaylov, W. A. Gattis, P. A. Gurbel, and C. M. O’Connor. “Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial).” Thromb Res 101, no. 6 (March 15, 2001): 427–33. https://doi.org/10.1016/s0049-3848(00)00431-x.

Gattis, W. A., and C. M. O’Connor. “Effect of amlodipine on mode of death in advanced heart failure.” Cardiology Review 18, no. 2 (March 12, 2001): 13–19.

Felker, G. M., and C. M. O’Connor. “Rational use of inotropic therapy in heart failure.” Curr Cardiol Rep 3, no. 2 (March 2001): 108–13. https://doi.org/10.1007/s11886-001-0035-8.

Gattis, W. A., A. Galanos, and C. M. O’Connor. “Angiotensin-converting enzyme inhibitor dosing in heart failure: what is optimal?” Am Heart J 141, no. 3 (March 2001): 331–33. https://doi.org/10.1067/mhj.2001.113228.

Shah, M. R., and C. M. O’connor. “The congestion score: a simple tool for a complicated disease?” Am Heart J 140, no. 6 (December 2000): 824–26. https://doi.org/10.1067/mhj.2000.110932.

O’Connor, C. M., W. A. Gattis, L. Shaw, M. S. Cuffe, and R. M. Califf. “Clinical characteristics and long-term outcomes of patients with heart failure and preserved systolic function.” Am J Cardiol 86, no. 8 (October 15, 2000): 863–67. https://doi.org/10.1016/s0002-9149(00)01107-3.

Nemeroff, C. B., and C. M. O’connor. “Introduction.” Am Heart J 140, no. 4 Suppl (October 2000): 55–56. https://doi.org/10.1067/mhj.2000.109976.

O’connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Depression and ischemic heart disease.” Am Heart J 140, no. 4 Suppl (October 2000): 63–69. https://doi.org/10.1067/mhj.2000.109979.

Varia, I., E. Logue, C. O’connor, K. Newby, H. R. Wagner, C. Davenport, K. Rathey, and K. R. Krishnan. “Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin.” Am Heart J 140, no. 3 (September 2000): 367–72. https://doi.org/10.1067/mhj.2000.108514.

Carson, P. A., C. M. O’Connor, A. B. Miller, S. Anderson, R. Belkin, G. W. Neuberg, J. H. Wertheimer, D. Frid, A. Cropp, and M. Packer. “Circadian rhythm and sudden death in heart failure: results from Prospective Randomized Amlodipine Survival Trial.” J Am Coll Cardiol 36, no. 2 (August 2000): 541–46. https://doi.org/10.1016/s0735-1097(00)00728-2.

Davis, C. J., P. A. Gurbel, W. A. Gattis, S. Y. Fuzaylov, G. V. Nair, C. M. O’Connor, and V. L. Serebruany. “Hemostatic abnormalities in patients with congestive heart failure: diagnostic significance and clinical challenge.” Int J Cardiol 75, no. 1 (August 2000): 15–21. https://doi.org/10.1016/s0167-5273(00)00300-4.

Kong, D. F., M. A. Blazing, and C. M. O’Connor. “Advances in the approach to acute coronary syndromes.” Hosp Pract (1995) 35, no. 4 (April 15, 2000): 61–64. https://doi.org/10.3810/hp.2000.04.192.

O’Connor, C. M., W. A. Gattis, and T. J. Ryan. “The role of clinical nonfatal end points in cardiovascular phase II/III clinical trials.” Am Heart J 139, no. 4 (April 2000): S143–54. https://doi.org/10.1016/s0002-8703(00)90062-0.

Serebruany, V. L., D. R. Lowry, S. Y. Fuzailov, D. J. Levine, C. M. O’Connor, and P. A. Gurbel. “Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction.” J Thromb Thrombolysis 9, no. 3 (April 2000): 229–34. https://doi.org/10.1023/a:1018762510842.

Califf, R. M., and C. M. O’Connor. “Beta-blocker therapy for heart failure: the evidence is in, now the work begins.” Jama 283, no. 10 (March 8, 2000): 1335–37. https://doi.org/10.1001/jama.283.10.1335.

Shah, A., G. S. Wagner, C. B. Granger, C. M. O’Connor, C. L. Green, K. M. Trollinger, R. M. Califf, and M. W. Krucoff. “Prognostic implications of TIMI flow grade in the infarct related artery compared with continuous 12-lead ST-segment resolution analysis. Reexamining the "gold standard" for myocardial reperfusion assessment.” J Am Coll Cardiol 35, no. 3 (March 1, 2000): 666–72. https://doi.org/10.1016/s0735-1097(99)00601-4.

Gurbel, P. A., D. J. Kereiakes, M. R. Dalesandro, R. D. Bahr, C. M. O’Connor, and V. L. Serebruany. “Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.” Am Heart J 139, no. 2 Pt 1 (February 2000): 320–28. https://doi.org/10.1067/mhj.2000.101109.

Bosworth, H. B., D. C. Steffens, M. N. Kuchibhatla, W. J. Jiang, R. M. Arias, C. M. O’Connor, and K. R. R. Krishnan. “The relationship of social support, social networks and negative events with depression in patients with coronary artery disease.” Aging and Mental Health 4, no. 3 (January 1, 2000): 253–58. https://doi.org/10.1080/713649927.

Cuffe, M. S., R. M. Califf, K. F. Adams, R. C. Bourge, W. Colucci, B. Massie, C. M. O’Connor, et al. “Rationale and design of the OPTIME CHF trial: outcomes of a prospective trial of intravenous milrinone for exacerbations of chronic heart failure.” Am Heart J 139, no. 1 Pt 1 (January 2000): 15–22. https://doi.org/10.1016/s0002-8703(00)90303-x.

Gattis, W., and C. M. O’Connor. “[Calcium antagonists in the treatment of heart failure. Re-evaluation of therapeutic strategies].” Drugs 59 Spec No 2 (2000): 17–24.

Gattis, W., and C. M. O’Connor. “Calcium antagonist use in heart failure: A re-evalutaion of treatment options.” Drugs 59, no. SPEC. ISS. 2 (January 1, 2000): 17–24. https://doi.org/10.2165/00003495-200059992-00003.

Gurbel, P. A., D. J. Kereiakes, M. R. Dalesandro, R. D. Bahr, C. M. O’Connor, and V. L. Serebruany. “Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.” American Heart Journal 139, no. 2 I (2000): 320–28.

Fortner, Molly R., Kristine Brown, Indu M. Varia, Kenneth R. Gersing, Christopher O’Connor, and P Murali Doraiswamy. “Effect of Bupropion SR on the Quality of Life of Elderly Depressed Patients With Comorbid Medical Disorders.” Prim Care Companion J Clin Psychiatry 1, no. 6 (December 1999): 174–79. https://doi.org/10.4088/pcc.v01n0601.

O’Connor, C. M., W. A. Gattis, M. Gheorghiade, C. B. Granger, J. Gilbert, J. M. McKenney, F. C. Messineo, et al. “A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: the U.S. ecadotril pilot safety study.” Am Heart J 138, no. 6 Pt 1 (December 1999): 1140–48. https://doi.org/10.1016/s0002-8703(99)70081-5.

Velazquez, E. J., and C. M. O’Connor. “Heart failure after myocardial infarction: A good heart is hard to find.” Am Heart J 138, no. 6 Pt 1 (December 1999): 1009–11. https://doi.org/10.1016/s0002-8703(99)70061-x.

Orloff, D. G., M. A. Blazing, and C. M. O’Connor. “Atherosclerotic disease in non-insulin-dependent diabetes mellitus: role of abnormal lipids and the place for lipid-altering therapies.” Am Heart J 138, no. 5 Pt 1 (November 1999): S406–12. https://doi.org/10.1016/s0002-8703(99)70043-8.

Del Carlo, C. H., and C. M. O’Connor. “Cardiac troponins in congestive heart failure.” Am Heart J 138, no. 4 Pt 1 (October 1999): 646–53. https://doi.org/10.1016/s0002-8703(99)70178-x.

Doraiswamy, P. M., J. MacFall, K. R. Krishnan, C. O’Connor, X. Wan, M. Benaur, M. Lewandowski, and M. Fortner. “Magnetic resonance assessment of cerebral perfusion in depressed cardiac patients: preliminary findings.” Am J Psychiatry 156, no. 10 (October 1999): 1641–43. https://doi.org/10.1176/ajp.156.10.1641.

Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada. The CARS Investigators (Coumadin/Aspirin Reinfarction Study).” Can J Cardiol 15, no. 10 (October 1999): 1095–1102.

Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada.” Canadian Journal of Cardiology 15, no. 10 (October 1, 1999): 1095–1102.

Gattis, W. A., V. Hasselblad, D. J. Whellan, and C. M. O’Connor. “Reduction in heart failure events by the addition of a clinical pharmacist to the heart failure management team: results of the Pharmacist in Heart Failure Assessment Recommendation and Monitoring (PHARM) Study.” Arch Intern Med 159, no. 16 (September 13, 1999): 1939–45. https://doi.org/10.1001/archinte.159.16.1939.

Gurbel, P. A., C. M. O’Connor, C. C. Cummings, and V. L. Serebruany. “Clopidogrel: the future choice for preventing platelet activation during coronary stenting?” Pharmacol Res 40, no. 2 (August 1999): 107–11. https://doi.org/10.1006/phrs.1999.0478.

Nair, G. V., P. A. Gurbel, C. M. O’Connor, W. A. Gattis, S. R. Murugesan, and V. L. Serebruany. “Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors.” Am J Cardiol 84, no. 3 (August 1, 1999): 321-A8. https://doi.org/10.1016/s0002-9149(99)00284-2.

Serebruany, V. L., S. R. Murugesan, A. Pothula, D. Atar, D. R. Lowry, C. M. O’Connor, and P. A. Gurbel. “Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy.” Eur J Heart Fail 1, no. 3 (August 1999): 243–49. https://doi.org/10.1016/s1388-9842(99)00029-x.

Blazing, M. A., and C. M. O’Connor. “Evidence supporting secondary prevention strategies.” Curr Opin Cardiol 14, no. 4 (July 1999): 303–9. https://doi.org/10.1097/00001573-199907000-00005.

O’Connor, C. M., P. W. Radensky, A. N. Unger, and B. C. Martin. “Hospital use and costs among patients with nonischemic cardiomyopathy in the first prospective randomized amlodipine survival evaluation study.” Clin Ther 21, no. 7 (July 1999): 1254–65. https://doi.org/10.1016/S0149-2918(00)80027-2.

O’Connor, C. M., W. A. Gattis, B. F. Uretsky, K. F. Adams, S. E. McNulty, S. H. Grossman, W. J. McKenna, et al. “Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST).” Am Heart J 138, no. 1 Pt 1 (July 1999): 78–86. https://doi.org/10.1016/s0002-8703(99)70250-4.

O’Connor, C. M., W. A. Gattis, and K. Swedberg. “Current and novel pharmacologic approaches in advanced heart failure.” Heart Lung 28, no. 4 (July 1999): 227–42. https://doi.org/10.1016/s0147-9563(99)70069-5.

Shapiro, P. A., F. Lespérance, N. Frasure-Smith, C. M. O’Connor, B. Baker, J. W. Jiang, P. Dorian, W. Harrison, and A. H. Glassman. “An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT Trial). Sertraline Anti-Depressant Heart Attack Trial.” Am Heart J 137, no. 6 (June 1999): 1100–1106. https://doi.org/10.1016/s0002-8703(99)70369-8.

Kong, D. F., M. A. Blazing, and C. M. O’Connor. “The health care burden of unstable angina.” Cardiol Clin 17, no. 2 (May 1999): 247–61. https://doi.org/10.1016/s0733-8651(05)70072-2.

O’Connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure.” Am J Cardiol 83, no. 9 (May 1, 1999): 1345–49. https://doi.org/10.1016/s0002-9149(99)00098-3.

Adams, K. F., C. A. Sueta, M. Gheorghiade, C. M. O’Connor, T. A. Schwartz, G. G. Koch, B. Uretsky, et al. “Gender differences in survival in advanced heart failure. Insights from the FIRST study.” Circulation 99, no. 14 (April 13, 1999): 1816–21. https://doi.org/10.1161/01.cir.99.14.1816.

Whellan, D. J., W. A. Gattis, L. Gaulden, B. Granger, and C. M. O’Connor. “Disease management of congestive heart failure.” Am J Manag Care 5, no. 4 (April 1999): 499–507.

O’Connor, C. M., W. A. Gattis, F. Zannad, S. E. McNulty, M. Gheorghiade, K. F. Adams, R. M. Califf, W. J. McKenna, J. Soler-Soler, and K. Swedberg. “Beta-blocker therapy in advanced heart failure: clinical characteristics and long-term outcomes.” Eur J Heart Fail 1, no. 1 (March 1999): 81–88. https://doi.org/10.1016/S1388-9842(98)00004-X.

Steffens, D. C., C. M. O’Connor, W. J. Jiang, C. F. Pieper, M. N. Kuchibhatla, R. M. Arias, A. Look, C. Davenport, M. B. Gonzalez, and K. R. Krishnan. “The effect of major depression on functional status in patients with coronary artery disease.” J Am Geriatr Soc 47, no. 3 (March 1999): 319–22. https://doi.org/10.1111/j.1532-5415.1999.tb02995.x.

Bart, B. A., and C. M. O’Connor. “Clinical determinants of mortality in patients with cardiomyopathy.” Cardiology Review 16, no. 7 (January 1, 1999): 8–11.

McKenzie, M. E., A. Pothula, P. A. Gurbel, S. Y. Fuzaylov, C. M. O’Connor, W. A. Gattis, and V. L. Serebruany. “Failure of thrombin generation markers to triage patients presenting with chest pain.” Cardiology 92, no. 1 (1999): 53–58. https://doi.org/10.1159/000006946.

Thel, M. C., and C. M. O’Connor. “Cardiopulmonary resuscitation: historical perspective to recent investigations.” Am Heart J 137, no. 1 (January 1999): 39–48. https://doi.org/10.1016/s0002-8703(99)70458-8.

O’Connor, C. M., P. E. Carson, A. B. Miller, M. L. Pressler, R. N. Belkin, G. W. Neuberg, D. J. Frid, et al. “Effect of amlodipine on mode of death among patients with advanced heart failure in the PRAISE trial. Prospective Randomized Amlodipine Survival Evaluation.” Am J Cardiol 82, no. 7 (October 1, 1998): 881–87. https://doi.org/10.1016/s0002-9149(98)00496-2.

Guyton, J. R., A. C. Goldberg, R. A. Kreisberg, D. L. Sprecher, H. R. Superko, and C. M. O’Connor. “Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia.” Am J Cardiol 82, no. 6 (September 15, 1998): 737–43. https://doi.org/10.1016/s0002-9149(98)00448-2.

Krishnan, K. R., L. K. George, C. F. Pieper, W. Jiang, R. Arias, A. Look, and C. O’Connor. “Depression and social support in elderly patients with cardiac disease.” Am Heart J 136, no. 3 (September 1998): 491–95. https://doi.org/10.1016/s0002-8703(98)70225-x.

Shah, B. R., C. Lin, C. Maynard, B. Bart, R. H. Selvester, L. K. Shaw, C. O’Connor, and G. S. Wagner. “Specificity of electrocardiographic myocardial infarction screening criteria in patients with nonischemic cardiomyopathies.” Am Heart J 136, no. 2 (August 1998): 314–19. https://doi.org/10.1053/hj.1998.v136.89909.

Gattis, W. A., R. L. Larsen, V. Hasselblad, B. A. Bart, and C. M. O’Connor. “Is optimal angiotensin-converting enzyme inhibitor dosing neglected in elderly patients with heart failure?” Am Heart J 136, no. 1 (July 1998): 43–48. https://doi.org/10.1016/s0002-8703(98)70180-2.

Serebruany, V. L., R. D. Bahr, C. M. O’Connor, D. R. Lowry, and P. A. Gurbel. “Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction. The GUSTO-III Platelet Substudy.” Cardiology 90, no. 1 (July 1998): 37–42. https://doi.org/10.1159/000006814.

O’Connor, C. M., W. A. Gattis, and K. Swedberg. “Current and novel pharmacologic approaches in advanced heart failure.” Am Heart J 135, no. 6 Pt 2 Su (June 1998): S249–63. https://doi.org/10.1016/s0002-8703(98)70254-6.

Serebruany, V. L., D. Atar, M. R. Dalesandro, C. M. O’Connor, and P. A. Gurbel. “Changes in hemostasis after parenteral magnesium in myocardial ischemia-reperfusion: from animal studies to clinical trials.” Magnes Res 11, no. 2 (June 1998): 133–40.

Flack, J. M., C. M. O’Connor, and J. Y. Wei. “Four commonly seen cardiovascular diseases.” Patient Care 32, no. 9 (May 15, 1998): 98–130.

Hassan, T. B., and D. B. Barnett. “Magnesium in in-hospital cardiac arrest.” Lancet 351, no. 9100 (February 7, 1998): 445–46. https://doi.org/10.1016/S0140-6736(05)78390-2.

Cuffe, M. S., and C. M. O’Connor. “Pharmacologic management of acute heart failure.” Current Opinion in Critical Care 3, no. 5 (December 1, 1997): 386–90.

Blumenthal, J. A., C. O’Connor, A. Hinderliter, K. Fath, S. B. Hegde, G. Miller, J. Puma, et al. “Psychosocial factors and coronary disease. A national multicenter clinical trial (ENRICHD) with a North Carolina focus.” N C Med J 58, no. 6 (November 1997): 440–44.

Thel, M. C., A. L. Armstrong, S. E. McNulty, R. M. Califf, and C. M. O’Connor. “Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff.” Lancet 350, no. 9087 (November 1, 1997): 1272–76. https://doi.org/10.1016/s0140-6736(97)05048-4.

Blumenthal, J. A., W. Jiang, M. A. Babyak, D. S. Krantz, D. J. Frid, R. E. Coleman, R. Waugh, et al. “Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms.” Arch Intern Med 157, no. 19 (October 27, 1997): 2213–23.

Bart, B. A., L. K. Shaw, C. B. McCants, D. F. Fortin, K. L. Lee, R. M. Califf, and C. M. O’Connor. “Clinical determinants of mortality in patients with angiographically diagnosed ischemic or nonischemic cardiomyopathy.” J Am Coll Cardiol 30, no. 4 (October 1997): 1002–8. https://doi.org/10.1016/s0735-1097(97)00235-0.

Jiang, W., W. R. Hathaway, S. McNulty, R. L. Larsen, K. L. Hansley, Y. Zhang, and C. M. O’Connor. “Ability of heart rate variability to predict prognosis in patients with advanced congestive heart failure.” Am J Cardiol 80, no. 6 (September 15, 1997): 808–11. https://doi.org/10.1016/s0002-9149(97)00526-2.

Hayano, J., W. Jiang, R. Waugh, C. O’Connor, D. Frid, and J. A. Blumenthal. “Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease.” Am Heart J 134, no. 3 (September 1997): 411–18. https://doi.org/10.1016/s0002-8703(97)70075-9.

O’Connor, C. M., W. R. Hathaway, E. R. Bates, J. D. Leimberger, K. N. Sigmon, D. J. Kereiakes, B. S. George, et al. “Clinical characteristics and long-term outcome of patients in whom congestive heart failure develops after thrombolytic therapy for acute myocardial infarction: development of a predictive model.” Am Heart J 133, no. 6 (June 1997): 663–73. https://doi.org/10.1016/s0002-8703(97)70168-6.

Gullette, E. C., J. A. Blumenthal, M. Babyak, W. Jiang, R. A. Waugh, D. J. Frid, C. M. O’Connor, J. J. Morris, and D. S. Krantz. “Effects of mental stress on myocardial ischemia during daily life.” Jama 277, no. 19 (May 21, 1997): 1521–26.

Bart, B. A., W. A. Gattis, S. J. Diem, and C. M. O’Connor. “Reasons for underuse of angiotensin-converting enzyme inhibitors in patients with heart failure and left ventricular dysfunction.” Am J Cardiol 79, no. 8 (April 15, 1997): 1118–20. https://doi.org/10.1016/s0002-9149(97)00060-x.

Allan, J. J. “Amlodipine in chronic heart failure.” N Engl J Med 336, no. 14 (April 3, 1997): 1023–24.

Packer, M., C. M. O’Connor, J. K. Ghali, M. L. Pressler, P. E. Carson, R. N. Belkin, A. B. Miller, et al. “Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group.” N Engl J Med 335, no. 15 (October 10, 1996): 1107–14. https://doi.org/10.1056/NEJM199610103351504.

Barefoot, J. C., M. J. Helms, D. B. Mark, J. A. Blumenthal, R. M. Califf, T. L. Haney, C. M. O’Connor, I. C. Siegler, and R. B. Williams. “Depression and long-term mortality risk in patients with coronary artery disease.” Am J Cardiol 78, no. 6 (September 15, 1996): 613–17. https://doi.org/10.1016/s0002-9149(96)00380-3.

Jiang, W., M. Babyak, D. S. Krantz, R. A. Waugh, R. E. Coleman, M. M. Hanson, D. J. Frid, et al. “Mental stress--induced myocardial ischemia and cardiac events.” Jama 275, no. 21 (June 5, 1996): 1651–56. https://doi.org/10.1001/jama.275.21.1651.

O’Connor, C. M., R. B. Meese, S. McNulty, K. D. Lucas, R. J. Carney, R. M. LeBoeuf, W. Maddox, et al. “A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction. The DUCCS-II Investigators.” Am J Cardiol 77, no. 10 (April 15, 1996): 791–97. https://doi.org/10.1016/s0002-9149(97)89171-0.

Mahaffey, K. W., C. B. Granger, R. Collins, C. M. O’Connor, E. M. Ohman, S. D. Bleich, J. J. Col, and R. M. Califf. “Overview of randomized trials of intravenous heparin in patients with acute myocardial infarction treated with thrombolytic therapy.” Am J Cardiol 77, no. 8 (March 15, 1996): 551–56. https://doi.org/10.1016/s0002-9149(97)89305-8.

Gonzalez, M. B., T. B. Snyderman, J. T. Colket, R. M. Arias, J. W. Jiang, C. M. O’Connor, and K. R. Krishnan. “Depression in patients with coronary artery disease.” Depression 4, no. 2 (1996): 57–62. https://doi.org/10.1002/(SICI)1522-7162(1996)4:2<57::AID-DEPR3>3.0.CO;2-C.

Jiang, W., M. A. Trauner, R. E. Coleman, R. A. Waugh, M. W. Hanson, D. J. Frid, B. G. Phillips, J. J. Morris, C. O’Connor, and J. A. Blumenthal. “Association of physical fitness and transient myocardial ischemia in patients with coronary artery disease.” J Cardiopulm Rehabil 15, no. 6 (November 1995): 431–38. https://doi.org/10.1097/00008483-199511000-00007.

Blumenthal, J. A., W. Jiang, R. A. Waugh, D. J. Frid, J. J. Morris, R. E. Coleman, M. Hanson, M. Babyak, E. T. Thyrum, and D. S. Krantz. “Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life. Association and hemodynamic features.” Circulation 92, no. 8 (October 15, 1995): 2102–8. https://doi.org/10.1161/01.cir.92.8.2102.

Thel, M. C., and C. M. O’Connor. “Magnesium in acute myocardial infarction.” Coron Artery Dis 6, no. 10 (October 1995): 831–37. https://doi.org/10.1097/00019501-199510000-00012.

Jiang, W., J. A. Blumenthal, M. W. Hanson, R. E. Coleman, C. M. O’Connor, D. Frid, J. J. Morris, and R. A. Waugh. “Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring.” Am J Cardiol 76, no. 5 (August 15, 1995): 350–54. https://doi.org/10.1016/s0002-9149(99)80099-x.

Mörike, K., and G. Mikus. “Zofenopril after anterior myocardial infarction.” N Engl J Med 332, no. 25 (June 22, 1995): 1715.

Campbell, P. T., J. S. Li, T. C. Wall, C. M. O’Connor, P. Van Trigt, R. T. Kenney, O. Melhus, and G. R. Corey. “Cytomegalovirus pericarditis: a case series and review of the literature.” Am J Med Sci 309, no. 4 (April 1995): 229–34. https://doi.org/10.1097/00000441-199504000-00009.

Selker, H. P., J. R. Beshansky, C. H. Schmid, J. L. Griffith, W. T. Longstreth, C. M. O’Connor, L. R. Caplan, E. W. Massey, R. B. D’Agostino, and M. M. Laks. “Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results.” Circulation 90, no. 4 (October 1994): 1657–61. https://doi.org/10.1161/01.cir.90.4.1657.

Larsen, R. L., V. S. Behar, S. R. Brazer, J. Chen, and C. M. O’Connor. “Chest pain presenting as ischemic heart disease. Congenital absence of the pericardium.” N C Med J 55, no. 7 (July 1994): 306–8.

O’Connor, C. M., R. Meese, R. Carney, J. Smith, E. Conn, J. Burks, C. Hartman, S. Roark, N. Shadoff, and M. Heard. “A randomized trial of intravenous heparin in conjunction with anistreplase (anisoylated plasminogen streptokinase activator complex) in acute myocardial infarction: the Duke University Clinical Cardiology Study (DUCCS) 1.” J Am Coll Cardiol 23, no. 1 (January 1994): 11–18. https://doi.org/10.1016/0735-1097(94)90496-0.

Van Trigt, P., J. Douglas, P. K. Smith, P. T. Campbell, T. C. Wall, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, and G. R. Corey. “A prospective trial of subxiphoid pericardiotomy in the diagnosis and treatment of large pericardial effusion. A follow-up report.” Ann Surg 218, no. 6 (December 1993): 777–82. https://doi.org/10.1097/00000658-199312000-00012.

Jiang, W., J. Hayano, E. R. Coleman, M. W. Hanson, D. J. Frid, C. O’Connor, D. Thurber, R. A. Waugh, and J. A. Blumenthal. “Relation of cardiovascular responses to mental stress and cardiac vagal activity in coronary artery disease.” Am J Cardiol 72, no. 7 (September 1, 1993): 551–54. https://doi.org/10.1016/0002-9149(93)90350-l.

Corey, G. R., P. T. Campbell, P. Van Trigt, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, J. A. Kisslo, and T. C. Wall. “Etiology of large pericardial effusions.” Am J Med 95, no. 2 (August 1993): 209–13. https://doi.org/10.1016/0002-9343(93)90262-n.

Kenney, R. T., J. S. Li, W. A. Clyde, T. C. Wall, C. M. O’Connor, P. T. Campbell, P. Van Trigt, and G. R. Corey. “Mycoplasmal pericarditis: evidence of invasive disease.” Clin Infect Dis 17 Suppl 1 (August 1993): S58–62. https://doi.org/10.1093/clinids/17.supplement_1.s58.

Krucoff, M. W., M. A. Croll, J. E. Pope, C. B. Granger, C. M. O’Connor, K. N. Sigmon, B. L. Wagner, J. A. Ryan, K. L. Lee, and D. J. Kereiakes. “Continuous 12-lead ST-segment recovery analysis in the TAMI 7 study. Performance of a noninvasive method for real-time detection of failed myocardial reperfusion.” Circulation 88, no. 2 (August 1993): 437–46. https://doi.org/10.1161/01.cir.88.2.437.

Slaughter, T. F., E. A. Mody, H. N. Oldham, J. G. Reves, C. M. O’Connor, J. K. Parker, and C. S. Greenberg. “Management of a patient with type IIC von Willebrand's disease during coronary artery bypass graft surgery.” Anesthesiology 78, no. 1 (January 1993): 195–97. https://doi.org/10.1097/00000542-199301000-00027.

Wall, T. C., P. T. Campbell, C. M. O’Connor, P. Van Trigt, R. T. Kenney, K. H. Sheikh, J. A. Kisslo, and G. R. Corey. “Diagnosis and management (by subxiphoid pericardiotomy) of large pericardial effusions causing cardiac tamponade.” Am J Cardiol 69, no. 12 (April 15, 1992): 1075–78. https://doi.org/10.1016/0002-9149(92)90866-w.

Campbell, P. T., P. Van Trigt, T. C. Wall, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, J. A. Kisslo, M. E. Baker, and G. R. Corey. “Subxiphoid pericardiotomy in the diagnosis and management of large pericardial effusions associated with malignancy.” Chest 101, no. 4 (April 1992): 938–43. https://doi.org/10.1378/chest.101.4.938.

Ortel, T. L., J. P. Gockerman, R. M. Califf, R. L. McCann, C. M. O’Connor, D. M. Metzler, and C. S. Greenberg. “Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.” Thromb Haemost 67, no. 3 (March 2, 1992): 292–96.

O’Connor, C. M., and R. M. Califf. “Aggressive therapy of acute MI in the elderly.” Hosp Pract (Off Ed) 27, no. 2 (February 15, 1992): 59-passim. https://doi.org/10.1080/21548331.1992.11705360.

Uglietta, J. P., C. M. O’Connor, O. B. Boyko, H. Aldrich, E. W. Massey, and E. R. Heinz. “CT patterns of intracranial hemorrhage complicating thrombolytic therapy for acute myocardial infarction.” Radiology 181, no. 2 (November 1991): 555–59. https://doi.org/10.1148/radiology.181.2.1924804.

Wallis, D. E., W. E. Boden, R. Califf, M. H. Crawford, A. H. Hakki, A. S. Iskandrian, A. Labovitz, C. O’Connor, R. Sutton, and P. J. Scanlon. “Failure of adjuvant heparin to reduce myocardial ischemia in the early treatment of patients with unstable angina.” Am Heart J 122, no. 4 Pt 1 (October 1991): 949–54. https://doi.org/10.1016/0002-8703(91)90456-r.

O’Connor, C. M., R. M. Califf, E. W. Massey, D. B. Mark, D. J. Kereiakes, R. J. Candela, C. Abbottsmith, B. George, R. S. Stack, and L. Aronson. “Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis.” J Am Coll Cardiol 16, no. 3 (September 1990): 533–40. https://doi.org/10.1016/0735-1097(90)90338-p.

Blumenthal, J. A., and C. O’Connor. “Stress and silent myocardial ischemia. A new research study at Duke University Medical Center.” N C Med J 51, no. 4 (April 1990): 135–38.

Mark, D. B., M. A. Hlatky, C. M. O’Connor, D. B. Pryor, T. C. Wall, M. B. Honan, H. R. Phillips, and R. M. Califf. “Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues.” J Am Coll Cardiol 12, no. 6 Suppl A (December 1988): 32A-43A. https://doi.org/10.1016/0735-1097(88)92639-3.

Stack, R. S., R. M. Califf, T. Hinohara, H. R. Phillips, D. B. Pryor, C. A. Simonton, E. B. Carlson, K. G. Morris, V. S. Behar, and Y. Kong. “Survival and cardiac event rates in the first year after emergency coronary angioplasty for acute myocardial infarction.” J Am Coll Cardiol 11, no. 6 (June 1988): 1141–49. https://doi.org/10.1016/0735-1097(88)90274-4.

Simonton, C. A., D. B. Mark, T. Hinohara, D. S. Rendall, H. R. Phillips, R. H. Peter, V. S. Behar, Y. Kong, W. G. O’Callaghan, and C. O’Connor. “Late restenosis after emergent coronary angioplasty for acute myocardial infarction: comparison with elective coronary angioplasty.” J Am Coll Cardiol 11, no. 4 (April 1988): 698–705. https://doi.org/10.1016/0735-1097(88)90198-2.

Hlatky, M. A., H. Cotugno, C. O’Connor, D. B. Mark, D. B. Pryor, and R. M. Califf. “Adoption of thrombolytic therapy in the management of acute myocardial infarction.” Am J Cardiol 61, no. 8 (March 1, 1988): 510–14. https://doi.org/10.1016/0002-9149(88)90755-2.

Hlatky, M. A., H. E. Cotugno, D. B. Mark, C. O’Connor, R. M. Califf, and D. B. Pryor. “Trends in physician management of uncomplicated acute myocardial infarction, 1970 to 1987.” Am J Cardiol 61, no. 8 (March 1, 1988): 515–18. https://doi.org/10.1016/0002-9149(88)90756-4.

Stack, R. S., C. M. O’Connor, D. B. Mark, T. Hinohara, H. R. Phillips, M. M. Lee, N. M. Ramirez, W. G. O’Callaghan, C. A. Simonton, and E. B. Carlson. “Coronary perfusion during acute myocardial infarction with a combined therapy of coronary angioplasty and high-dose intravenous streptokinase.” Circulation 77, no. 1 (January 1988): 151–61. https://doi.org/10.1161/01.cir.77.1.151.

Boswick, J. M., K. L. Lee, L. G. Aronson, C. M. O’Connor, M. B. Honan, R. M. Califf, and D. B. Pryor. “USE OF COMPUTERIZED STATISTICAL MODELS TO EDUCATE MEDICAL HOUSESTAFF IN ESTIMATING CLINICAL OUTCOMES.” Proceedings  Annual Symposium on Computer Applications in Medical Care, December 1, 1987, 162–65.

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Brooks, R. A., L. G. Mitchell, C. M. O’Connor, and G. Di Chiro. “On the relationship between computed tomography numbers and specific gravity.” Phys Med Biol 26, no. 1 (January 1981): 141–47. https://doi.org/10.1088/0031-9155/26/1/014.

Rieth, K. G., K. Fujiwara, G. Di Chiro, I. Klatzo, R. A. Brooks, G. S. Johnston, C. M. O’Connor, and L. G. Mitchell. “Serial measurements of CT attenuation and specific gravity in experimental cerebral edema.” Radiology 135, no. 2 (May 1980): 343–48. https://doi.org/10.1148/radiology.135.2.6768102.

Sheridan, W. T., M. R. Keller, C. M. O’Connor, R. A. Brooks, and K. M. Hanson. “Evaluation of edge-induced streaking artifacts in CT scanners.” Med Phys 7, no. 2 (March 1980): 108–11. https://doi.org/10.1118/1.594673.

Koenig, Harold G., Christopher M. O’Connor, Steven A. Guarisco, K Michael Zabel, and Stephen M. Ford. “Depressive Disorder in Older Medical Inpatients on General Medicine and Cardiology Services at a University Teaching Hospital.” Am J Geriatr Psychiatry 1, no. 3 (n.d.): 197–210. https://doi.org/10.1097/00019442-199300130-00004.

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Mentz, Robert J., Christopher M. O’Connor, Bradi B. Granger, Hongqiu Yang, Chetan B. Patel, Karen E. Steinhauser, Mona Fiuzat, et al. “Palliative care and hospital readmissions in patients with advanced heart failure: Insights from the PAL-HF trial.” In Am Heart J, 204:202–4, 2018. https://doi.org/10.1016/j.ahj.2018.07.010.

Pokorney, Sean D., Sana M. Al-Khatib, Jie-Lena Sun, Phillip Schulte, Christopher M. O’Connor, John R. Teerlink, Paul W. Armstrong, et al. “Sudden cardiac death after acute heart failure hospital admission: insights from ASCEND-HF.” In Eur J Heart Fail, 20:525–32, 2018. https://doi.org/10.1002/ejhf.1078.

DeVore, Adam D., Vic Hasselblad, Robert J. Mentz, Christopher M. O’Connor, Paul W. Armstrong, John J. McMurray, Justin A. Ezekowitz, et al. “Loop diuretic dose adjustments after a hospitalization for heart failure: insights from ASCEND-HF.” In Eur J Heart Fail, 17:340–46, 2015. https://doi.org/10.1002/ejhf.235.

Valente, Mattia A. E., Adriaan A. Voors, Kevin Damman, Dirk J. Van Veldhuisen, Barrie M. Massie, Christopher M. O’Connor, Marco Metra, et al. “Diuretic response in acute heart failure: clinical characteristics and prognostic significance.” In Eur Heart J, 35:1284–93, 2014. https://doi.org/10.1093/eurheartj/ehu065.

Wilcox, Jane E., Gregg C. Fonarow, Yan Zhang, Nancy M. Albert, Anne B. Curtis, Mihai Gheorghiade, J Thomas Heywood, et al. “Clinical effectiveness of cardiac resynchronization and implantable cardioverter-defibrillator therapy in men and women with heart failure: findings from IMPROVE HF.” In Circ Heart Fail, 7:146–53, 2014. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000789.