Scholars@Duke

Academic Articles

• Butler, Javed, Yinggan Zheng, Muhammad Shahzeb Khan, Diana Bonderman, Lars H. Lund, Christopher R. deFilippi, Robert O. Blaustein, et al. “Ejection Fraction, Biomarkers, and Outcomes and Impact of Vericiguat on Outcomes Across EF in VICTORIA.” Jacc Heart Fail 11, no. 5 (May 2023): 583–92. https://doi.org/10.1016/j.jchf.2022.12.014.
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• Collins, Katherine A., Gordon R. Reeves, Nancy Houston Miller, David J. Whellan, Christopher M. O’Connor, Bess H. Marcus, Dalane W. Kitzman, William E. Kraus, and William E. HF-ACTION Investigators. “Clinical Predictors of Adherence to Exercise Training Among Individuals With Heart Failure: THE HF-ACTION STUDY.” J Cardiopulm Rehabil Prev 43, no. 3 (May 1, 2023): 205–13. https://doi.org/10.1097/HCR.0000000000000757.
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• Defilippi, Christopher R., Wendimagegn G. Alemayehu, Adriaan A. Voors, David Kaye, Robert O. Blaustein, Javed Butler, Justin A. Ezekowitz, et al. “Assessment of Biomarkers of Myocardial injury, Inflammation, and Renal Function in Heart Failure With Reduced Ejection Fraction: The VICTORIA Biomarker Substudy.” J Card Fail 29, no. 4 (April 2023): 448–58. https://doi.org/10.1016/j.cardfail.2022.12.013.
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• Pieske, Burkert, Elisabeth Pieske-Kraigher, Carolyn S. P. Lam, Vojtěch Melenovský, Karen Sliwa, Yuri Lopatin, Juan Luis Arango, et al. “Effect of vericiguat on left ventricular structure and function in patients with heart failure with reduced ejection fraction: the VICTORIA echocardiographic substudy.” Eur J Heart Fail, March 30, 2023. https://doi.org/10.1002/ejhf.2836.
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• Felker, G Michael, Rebecca North, Hillary Mulder, W Schuyler Jones, Kevin J. Anstrom, Mahesh J. Patel, Javed Butler, et al. “Clinical Implications of Negatively Adjudicated Heart Failure Events: Data From the VICTORIA Study.” Circulation 147, no. 8 (February 21, 2023): 694–96. https://doi.org/10.1161/CIRCULATIONAHA.122.062055.
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• Bhatt, Ankeet S., Matthew Dimond, Mona Fiuzat, Muthiah Vaduganathan, Orly Vardeny, Punag Divanji, Jan Komtebedde, et al. “Impact of COVID-19 on Heart Failure Clinical Trials: Insights From the Heart Failure Collaboratory.” Jacc Heart Fail 11, no. 2 (February 2023): 254–57. https://doi.org/10.1016/j.jchf.2022.11.024.
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• Harrington, Josephine, Andrew B. Nixon, Melissa A. Daubert, Eric Yow, James Januzzi, Mona Fiuzat, David J. Whellan, et al. “Circulating Angiokines Are Associated With Reverse Remodeling and Outcomes in Chronic Heart Failure.” J Card Fail, January 8, 2023. https://doi.org/10.1016/j.cardfail.2022.12.011.
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• Farsky, Pedro S., Jennifer White, Hussein R. Al-Khalidi, Carla A. Sueta, Jean L. Rouleau, Julio A. Panza, Eric J. Velazquez, Christopher M. O’Connor, and Christopher M. Working Group and Surgical Treatment for Ischemic Heart Failure Trial Investigators. “Optimal medical therapy with or without surgical revascularization and long-term outcomes in ischemic cardiomyopathy.” J Thorac Cardiovasc Surg 164, no. 6 (December 2022): 1890-1899.e4. https://doi.org/10.1016/j.jtcvs.2020.12.094.
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• Psotka, Mitchell A., William T. Abraham, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Tariq Ahmad, G Michael Felker, et al. “Functional and Symptomatic Clinical Trial Endpoints: The HFC-ARC Scientific Expert Panel.” Jacc Heart Fail 10, no. 12 (December 2022): 889–901. https://doi.org/10.1016/j.jchf.2022.09.012.
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• Butler, Javed, Muhammad Shariq Usman, Kevin J. Anstrom, Robert O. Blaustein, Marc P. Bonaca, Justin A. Ezekowitz, Cecilia Freitas, et al. “Soluble guanylate cyclase stimulators in patients with heart failure with reduced ejection fraction across the risk spectrum.” Eur J Heart Fail 24, no. 11 (November 2022): 2029–36. https://doi.org/10.1002/ejhf.2720.
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• Sharma, Abhinav, Carolyn S. P. Lam, Wan Ting Tay, Jonathan Yap, Michael R. MacDonald, Amir Razaghizad, Lauren B. Cooper, et al. “Cause of Death Among Patients With Diabetes and Heart Failure With Reduced Ejection Fraction.” Jacc Asia 2, no. 5 (October 2022): 648–50. https://doi.org/10.1016/j.jacasi.2022.05.002.
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• Tehrani, Behnam N., Matthew W. Sherwood, Carolyn Rosner, Alexander G. Truesdell, Seiyon Ben Lee, Abdulla A. Damluji, Mehul Desai, et al. “A Standardized and Regionalized Network of Care for Cardiogenic Shock.” Jacc. Heart Failure 10, no. 10 (October 2022): 768–81. https://doi.org/10.1016/j.jchf.2022.04.004.
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• Armstrong, Paul W., Yinggan Zheng, Richard W. Troughton, Lars H. Lund, Jian Zhang, Carolyn S. P. Lam, Cynthia M. Westerhout, et al. “Sequential Evaluation of NT-proBNP in Heart Failure: Insights Into Clinical Outcomes and Efficacy of Vericiguat.” Jacc Heart Fail 10, no. 9 (September 2022): 677–88. https://doi.org/10.1016/j.jchf.2022.04.015.
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• Lala, Anuradha, Christopher M. O’Connor, Mona Fiuzat, Mark H. Drazner, and Robert J. Mentz. “Recognizing Efforts that Support Clinical Trial Success: Site-Based Research Awards from the Heart Failure Collaboratory and Heart Failure Society of America.” J Card Fail 28, no. 9 (September 2022): 1387–89. https://doi.org/10.1016/j.cardfail.2022.08.001.
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• Pierce, Jacob B., Robert J. Mentz, Jie-Lena Sun, Brooke Alhanti, David J. Whellan, William E. Kraus, Ileana L. Piña, Mona Fiuzat, Christopher M. O’Connor, and Stephen J. Greene. “Titration of medical therapy and clinical outcomes among patients with heart failure with reduced ejection fraction: Findings from the HF-ACTION trial.” Am Heart J 251 (September 2022): 115–26. https://doi.org/10.1016/j.ahj.2022.05.018.
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• Senni, Michele, Wendimagegn G. Alemayehu, David Sim, Frank Edelmann, Javed Butler, Justin Ezekowitz, Adrian F. Hernandez, et al. “Efficacy and safety of vericiguat in patients with heart failure with reduced ejection fraction treated with sacubitril/valsartan: insights from the VICTORIA trial.” Eur J Heart Fail 24, no. 9 (September 2022): 1614–22. https://doi.org/10.1002/ejhf.2608.
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• Pandey, Ambarish, Matthew W. Segar, Sumitabh Singh, Gordon R. Reeves, Christopher O’Connor, Ileana Piña, David Whellan, William E. Kraus, Robert J. Mentz, and Dalane W. Kitzman. “Frailty Status Modifies the Efficacy of Exercise Training Among Patients With Chronic Heart Failure and Reduced Ejection Fraction: An Analysis From the HF-ACTION Trial.” Circulation 146, no. 2 (July 12, 2022): 80–90. https://doi.org/10.1161/CIRCULATIONAHA.122.059983.
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• Greene, Stephen J., Justin A. Ezekowitz, Kevin J. Anstrom, Vladimir Demyanenko, Michael M. Givertz, Ileana L. Piña, Christopher M. O’Connor, et al. “Medical Therapy During Hospitalization for Heart Failure With Reduced Ejection Fraction: The VICTORIA Registry.” J Card Fail 28, no. 7 (July 2022): 1063–77. https://doi.org/10.1016/j.cardfail.2022.02.011.
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• Butler, Javed, Amanda Stebbins, Vojtěch Melenovský, Nancy K. Sweitzer, Martin R. Cowie, Josef Stehlik, Muhammad Shahzeb Khan, et al. “Vericiguat and Health-Related Quality of Life in Patients With Heart Failure With Reduced Ejection Fraction: Insights From the VICTORIA Trial.” Circ Heart Fail 15, no. 6 (June 2022): e009337. https://doi.org/10.1161/CIRCHEARTFAILURE.121.009337.
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• O’Connor, Christopher. “Thank You for the Privilege.” Jacc Heart Fail 10, no. 6 (June 2022): 441–43. https://doi.org/10.1016/j.jchf.2022.04.007.
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• Sinha, Shashank S., Carolyn M. Rosner, Behnam N. Tehrani, Aneel Maini, Alexander G. Truesdell, Seiyon Ben Lee, Pramita Bagchi, et al. “Cardiogenic Shock From Heart Failure Versus Acute Myocardial Infarction: Clinical Characteristics, Hospital Course, and 1-Year Outcomes.” Circ Heart Fail 15, no. 6 (June 2022): e009279. https://doi.org/10.1161/CIRCHEARTFAILURE.121.009279.
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• DeFilippis, Ersilia M., Melvin Echols, Philip B. Adamson, Wayne B. Batchelor, Lauren B. Cooper, Lawton S. Cooper, Patrice Desvigne-Nickens, et al. “Improving Enrollment of Underrepresented Racial and Ethnic Populations in Heart Failure Trials: A Call to Action From the Heart Failure Collaboratory.” Jama Cardiol 7, no. 5 (May 1, 2022): 540–48. https://doi.org/10.1001/jamacardio.2022.0161.
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• O’Connor, C. “Editorial Regrets and Opportunities: JACC: Heart Failure.” Jacc: Heart Failure 10, no. 5 (May 1, 2022): 363–64. https://doi.org/10.1016/j.jchf.2022.03.005.
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• Saldarriaga, Clara, Dan Atar, Amanda Stebbins, Basil S. Lewis, Imran Zainal Abidin, Robert O. Blaustein, Javed Butler, et al. “Vericiguat in patients with coronary artery disease and heart failure with reduced ejection fraction.” Eur J Heart Fail 24, no. 5 (May 2022): 782–90. https://doi.org/10.1002/ejhf.2468.
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• Rosner, Carolyn M., Melany Atkins, Ibrahim M. Saeed, James A. de Lemos, Amit Khera, Alireza Maghsoudi, Jean Min, Behnam N. Tehrani, Christopher M. O’Connor, and Christopher R. deFilippi. “Patients With Myocarditis Associated With COVID-19 Vaccination.” J Am Coll Cardiol 79, no. 13 (April 5, 2022): 1317–19. https://doi.org/10.1016/j.jacc.2022.02.004.
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• O’Connor, Christopher M. “Editorial Privilege.” Jacc Heart Fail 10, no. 4 (April 2022): 290. https://doi.org/10.1016/j.jchf.2022.02.002.
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• Tobin, Rachel S., Michael F. Cosiano, Christopher M. O’Connor, Mona Fiuzat, Bradi B. Granger, Joseph G. Rogers, James A. Tulsky, Karen E. Steinhauser, and Robert J. Mentz. “Spirituality in Patients With Heart Failure.” Jacc Heart Fail 10, no. 4 (April 2022): 217–26. https://doi.org/10.1016/j.jchf.2022.01.014.
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• Cooper, Lauren B., Scott Bruce, Mitchell Psotka, Robert Mentz, Rachel Bell, Stephen L. Seliger, Christopher O’Connor, and Christopher deFilippi. “Proteomic differences among patients with heart failure taking furosemide or torsemide.” Clin Cardiol 45, no. 3 (March 2022): 265–72. https://doi.org/10.1002/clc.23733.
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• O’Connor, Christopher M. “Implementation Noise.” Jacc Heart Fail 10, no. 3 (March 2022): 211–12. https://doi.org/10.1016/j.jchf.2022.01.001.
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• Fiuzat, Mona, Carine E. Hamo, Javed Butler, William T. Abraham, Ersilia M. DeFilippis, Gregg C. Fonarow, Joann Lindenfeld, et al. “Optimal Background Pharmacological Therapy for Heart Failure Patients in Clinical Trials: JACC Review Topic of the Week.” J Am Coll Cardiol 79, no. 5 (February 8, 2022): 504–10. https://doi.org/10.1016/j.jacc.2021.11.033.
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• Ijaz, Naila, Brian Buta, Qian-Li Xue, Denise T. Mohess, Archana Bushan, Henry Tran, Wayne Batchelor, et al. “Interventions for Frailty Among Older Adults With Cardiovascular Disease: JACC State-of-the-Art Review.” J Am Coll Cardiol 79, no. 5 (February 8, 2022): 482–503. https://doi.org/10.1016/j.jacc.2021.11.029.
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• Abraham, William T., Jonathan P. Piccini, Christopher Dufton, Ian A. Carroll, Jeffrey S. Healey, Christopher M. O’Connor, Debra Marshall, et al. “Dose-limiting, adverse event-associated bradycardia with β-blocker treatment of atrial fibrillation in the GENETIC-AF trial.” Heart Rhythm O2 3, no. 1 (February 2022): 40–49. https://doi.org/10.1016/j.hroo.2021.11.005.
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• Ezekowitz, Justin A., Wendimagegn Alemayehu, Sarah Rathwell, Andrew D. Grant, Mona Fiuzat, David J. Whellan, Tariq Ahmad, et al. “The influence of comorbidities on achieving an N-terminal pro-b-type natriuretic peptide target: a secondary analysis of the GUIDE-IT trial.” Esc Heart Fail 9, no. 1 (February 2022): 77–86. https://doi.org/10.1002/ehf2.13692.
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• Granger, Bradi B., James A. Tulsky, Brystana G. Kaufman, Robert M. Clare, Kevin Anstrom, Daniel B. Mark, Kimberly A. Johnson, et al. “Polypharmacy in Palliative Care for Advanced Heart Failure: The PAL-HF Experience.” J Card Fail 28, no. 2 (February 2022): 334–38. https://doi.org/10.1016/j.cardfail.2021.08.021.
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• O’Connor, Christopher. “Behavioral Benefits of COVID Lockdown for Heart Failure Patients: A New Therapeutic Intervention?” Jacc Heart Fail 10, no. 2 (February 2022): 142–43. https://doi.org/10.1016/j.jchf.2021.12.001.
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• Tobin, Rachel S., Marc D. Samsky, Maragatha Kuchibhatla, Christopher M. O’Connor, Mona Fiuzat, Haider J. Warraich, Kevin J. Anstrom, et al. “Race Differences in Quality of Life following a Palliative Care Intervention in Patients with Advanced Heart Failure: Insights from the Palliative Care in Heart Failure Trial.” J Palliat Med 25, no. 2 (February 2022): 296–300. https://doi.org/10.1089/jpm.2021.0220.
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• Ostrominski, John W., Sameer Hirji, Ankeet S. Bhatt, Javed Butler, Mona Fiuzat, Gregg C. Fonarow, Paul A. Heidenreich, et al. “Cost and Value in Contemporary Heart Failure Clinical Guidance Documents.” Jacc Heart Fail 10, no. 1 (January 2022): 1–11. https://doi.org/10.1016/j.jchf.2021.08.002.
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• Pahuja, Mohit, Eric S. Leifer, John-Ross D. Clarke, Tariq Ahmad, Melissa A. Daubert, Daniel B. Mark, Lawton Cooper, et al. “Assessing race and ethnicity differences in outcomes based on GDMT and target NT-proBNP in patients with heart failure with reduced ejection fraction: An analysis of the GUIDE-IT study.” Prog Cardiovasc Dis 71 (2022): 79–85. https://doi.org/10.1016/j.pcad.2022.04.010.
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• Chouairi, Fouad, Michael A. Fuery, Clancy W. Mullan, Cesar Caraballo, Sounok Sen, Christopher Maulion, Samuel T. Wilkinson, et al. “The Impact of Depression on Outcomes in Patients With Heart Failure and Reduced Ejection Fraction Treated in the GUIDE-IT Trial.” Journal of Cardiac Failure 27, no. 12 (December 2021): 1359–66. https://doi.org/10.1016/j.cardfail.2021.06.008.
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• Costanzo, M. R., C. M. O’Connor, and H. O. Ventura. “Advanced Heart Failure: Progress and Disappointments.” Jacc: Heart Failure 9, no. 12 (December 1, 2021): 938–40. https://doi.org/10.1016/j.jchf.2021.10.005.
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• Wan, Luxi, Marc D. Samsky, Christopher M. O’Connor, Amanda Stebbins, Brooke Alhanti, Haider J. Warraich, Kimberly S. Johnson, et al. “Patterns of Change in Individual Domains of the Kansas City Cardiomyopathy Questionnaire With a Palliative Care Intervention for Patients With Advanced Heart Failure: Insights from PAL-HF.” J Card Fail 27, no. 12 (December 2021): 1476–78. https://doi.org/10.1016/j.cardfail.2021.02.007.
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• Ezekowitz, Justin A., Yinggan Zheng, Alain Cohen-Solal, Vojtěch Melenovský, Jorge Escobedo, Javed Butler, Adrian F. Hernandez, et al. “Hemoglobin and Clinical Outcomes in the Vericiguat Global Study in Patients With Heart Failure and Reduced Ejection Fraction (VICTORIA).” Circulation 144, no. 18 (November 2, 2021): 1489–99. https://doi.org/10.1161/CIRCULATIONAHA.121.056797.
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• Luo, Nancy, Christopher M. O’Connor, Karen Chiswell, Kevin J. Anstrom, L Kristin Newby, and Robert J. Mentz. “Survival in Patients With Nonischemic Cardiomyopathy With Preserved vs Reduced Ejection Fraction.” Cjc Open 3, no. 11 (November 2021): 1333–40. https://doi.org/10.1016/j.cjco.2021.06.007.
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• Zeitler, E. P., C. M. O’Connor, W. Abraham, and J. A. Lindenfeld. “How Is Medical Device Innovation Currently Supported in the U.S.?: From the Heart Failure Collaboratory.” Jacc: Heart Failure 9, no. 11 (November 1, 2021): 855–57. https://doi.org/10.1016/j.jchf.2021.09.005.
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• Greenberg, Barry, Christopher M. O’Connor, and G Michael Felker. “Classifying Heart Failure in the 21st Century: Matching Taxonomy With Science.” Jacc Heart Fail 9, no. 10 (October 2021): 771–73. https://doi.org/10.1016/j.jchf.2021.08.004.
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• Mentz, Robert J., David J. Whellan, Gordon R. Reeves, Amy M. Pastva, Pamela Duncan, Bharathi Upadhya, M Benjamin Nelson, et al. “Rehabilitation Intervention in Older Patients With Acute Heart Failure With Preserved Versus Reduced Ejection Fraction.” Jacc Heart Fail 9, no. 10 (October 2021): 747–57. https://doi.org/10.1016/j.jchf.2021.05.007.
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• Anchouche, Khalil, Malik Elharram, Emily Oulousian, Amir Razaghizad, Robert Avram, Guillaume Marquis-Gravel, Varinder Kaur Randhawa, et al. “Use of Actigraphy (Wearable Digital Sensors to Monitor Activity) in Heart Failure Randomized Clinical Trials: A Scoping Review.” Can J Cardiol 37, no. 9 (September 2021): 1438–49. https://doi.org/10.1016/j.cjca.2021.07.001.
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• Ezekowitz, Justin, Robert J. Mentz, Cynthia M. Westerhout, Nancy K. Sweitzer, Michael M. Givertz, Ileana L. Piña, Christopher M. O’Connor, et al. “Participation in a Heart Failure Clinical Trial: Perspectives and Opportunities From the VICTORIA Trial and VICTORIA Simultaneous Registry.” Circ Heart Fail 14, no. 9 (September 2021): e008242. https://doi.org/10.1161/CIRCHEARTFAILURE.120.008242.
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• Fudim, Marat, Toi Spates, Jie-Lena Sun, Veraprapas Kittipibul, Jeffrey M. Testani, Randall C. Starling, WH Wilson Tang, et al. “Early diuretic strategies and the association with In-hospital and Post-discharge outcomes in acute heart failure.” Am Heart J 239 (September 2021): 110–19. https://doi.org/10.1016/j.ahj.2021.05.011.
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• Ibrahim, Nasrien E., Christopher M. O’Connor, and James L. Januzzi. “From Clinical Trials to Communities: The 5 C's of Ensuring Equitable Delivery of Heart Failure Therapies.” Jacc Heart Fail 9, no. 9 (September 2021): 694–96. https://doi.org/10.1016/j.jchf.2021.08.001.
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• Rosner, Carolyn M., Leonard Genovese, Behnam N. Tehrani, Melany Atkins, Hooman Bakhshi, Saquib Chaudhri, Abdulla A. Damluji, et al. “Myocarditis Temporally Associated With COVID-19 Vaccination.” Circulation 144, no. 6 (August 10, 2021): 502–5. https://doi.org/10.1161/CIRCULATIONAHA.121.055891.
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• Ponikowski, Piotr, Wendimagegn Alemayehu, Ali Oto, M Cecilia Bahit, Ebrahim Noori, Mahesh J. Patel, Javed Butler, et al. “Vericiguat in patients with atrial fibrillation and heart failure with reduced ejection fraction: insights from the VICTORIA trial.” European Journal of Heart Failure 23, no. 8 (August 2021): 1300–1312. https://doi.org/10.1002/ejhf.2285.
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• Psotka, Mitchell A., Christopher M. O’Connor, and John R. Teerlink. “Empower the Future… Even Oprah Had a Mentor!.” Jacc Heart Fail 9, no. 8 (August 2021): 604–5. https://doi.org/10.1016/j.jchf.2021.06.006.
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• Voors, Adriaan A., Hillary Mulder, Eugene Reyes, Martin R. Cowie, Johan Lassus, Adrian F. Hernandez, Justin A. Ezekowitz, et al. “Renal function and the effects of vericiguat in patients with worsening heart failure with reduced ejection fraction: insights from the VICTORIA (Vericiguat Global Study in Subjects with HFrEF) trial.” Eur J Heart Fail 23, no. 8 (August 2021): 1313–21. https://doi.org/10.1002/ejhf.2221.
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• Kitzman, Dalane W., David J. Whellan, Pamela Duncan, Amy M. Pastva, Robert J. Mentz, Gordon R. Reeves, M Benjamin Nelson, et al. “Physical Rehabilitation for Older Patients Hospitalized for Heart Failure.” N Engl J Med 385, no. 3 (July 15, 2021): 203–16. https://doi.org/10.1056/NEJMoa2026141.
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• Lang, Ninian N., Faheem A. Ahmad, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jorg Taubel, et al. “Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial.” Eur J Heart Fail 23, no. 7 (July 2021): 1147–55. https://doi.org/10.1002/ejhf.2138.
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• Ahmad, Tariq, and Christopher O’Connor. “Change Is the Only Constant in Heart Failure.” Jacc Heart Fail 9, no. 7 (July 2021): 528–29. https://doi.org/10.1016/j.jchf.2021.06.001.
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• Fuery, Michael A., Fouad Chouairi, James L. Januzzi, Gordon W. Moe, Cesar Caraballo, Megan McCullough, P Elliott Miller, et al. “Intercountry Differences in Guideline-Directed Medical Therapy and Outcomes Among Patients With Heart Failure.” Jacc Heart Fail 9, no. 7 (July 2021): 497–505. https://doi.org/10.1016/j.jchf.2021.02.011.
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• Markousis-Mavrogenis, George, Jasper Tromp, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “The Additive Prognostic Value of Serial Plasma Interleukin-6 Levels over Changes in Brain Natriuretic Peptide in Patients with Acute Heart Failure.” J Card Fail 27, no. 7 (July 2021): 808–11. https://doi.org/10.1016/j.cardfail.2021.01.008.
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• Whellan, David J., and Christopher M. O’Connor. “Function Follows Form.” Jacc Heart Fail 9, no. 7 (July 2021): 482–83. https://doi.org/10.1016/j.jchf.2021.02.012.
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• Mentz, Robert J., Hillary Mulder, Arend Mosterd, Nancy K. Sweitzer, Michele Senni, Javed Butler, Justin A. Ezekowitz, et al. “Clinical Outcome Predictions for the VerICiguaT Global Study in Subjects With Heart Failure With Reduced Ejection Fraction (VICTORIA) Trial.” J Card Fail, June 24, 2021. https://doi.org/10.1016/j.cardfail.2021.05.016.
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• Batchelor, Wayne B., Abdulla A. Damluji, Celina Yong, Mona Fiuzat, Scott D. Barnett, David E. Kandzari, Matthew W. Sherwood, et al. “Does study subject diversity influence cardiology research site performance?: Insights from 2 U.S. National Coronary Stent Registries.” Am Heart J 236 (June 2021): 37–48. https://doi.org/10.1016/j.ahj.2021.02.003.
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• Kaufman, Brystana G., Bradi B. Granger, Jie-Lena Sun, Gillian Sanders, Donald H. Taylor, Daniel B. Mark, Haider Warraich, et al. “The Cost-Effectiveness of Palliative Care: Insights from the PAL-HF Trial.” J Card Fail 27, no. 6 (June 2021): 662–69. https://doi.org/10.1016/j.cardfail.2021.02.019.
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• Lam, Carolyn S. P., Anna Giczewska, Karen Sliwa, Frank Edelmann, Jens Refsgaard, Edimar Bocchi, Justin A. Ezekowitz, et al. “Clinical Outcomes and Response to Vericiguat According to Index Heart Failure Event: Insights From the VICTORIA Trial.” Jama Cardiol 6, no. 6 (June 1, 2021): 706–12. https://doi.org/10.1001/jamacardio.2020.6455.
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• O’Connor, Christopher M., Joseph Rogers, and JoAnn Lindenfeld. “Device Development in the Gray Zone: One Step Forward.” Jacc Heart Fail 9, no. 6 (June 2021): 463–64. https://doi.org/10.1016/j.jchf.2021.05.001.
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• Perez, Antonio L., Justin L. Grodin, Thanat Chaikijurajai, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, et al. “Interleukin-6 and Outcomes in Acute Heart Failure: An ASCEND-HF Substudy.” J Card Fail 27, no. 6 (June 2021): 670–76. https://doi.org/10.1016/j.cardfail.2021.01.006.
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• Tehrani, Behnam N., Abdulla A. Damluji, Matthew W. Sherwood, Carolyn Rosner, Alexander G. Truesdell, Kelly C. Epps, Edward Howard, et al. “Transradial access in acute myocardial infarction complicated by cardiogenic shock: Stratified analysis by shock severity.” Catheter Cardiovasc Interv 97, no. 7 (June 1, 2021): 1354–66. https://doi.org/10.1002/ccd.29098.
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• Blumer, Vanessa, Stephen J. Greene, Angie Wu, Javed Butler, Justin A. Ezekowitz, JoAnn Lindenfeld, Brooke Alhanti, Adrian F. Hernandez, Christopher M. O’Connor, and Robert J. Mentz. “Sex Differences in Clinical Course and Patient-Reported Outcomes Among Patients Hospitalized for Heart Failure.” Jacc Heart Fail 9, no. 5 (May 2021): 336–45. https://doi.org/10.1016/j.jchf.2020.12.011.
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• Lindenfeld, JoAnn, Mona Fiuzat, and Christopher O’Connor. “Promoting Diversity in Clinical Trial Leadership: A Call to Action.” Jacc Heart Fail 9, no. 5 (May 2021): 401–2. https://doi.org/10.1016/j.jchf.2021.03.005.
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• Bhatt, Ankeet S., Mona Fiuzat, JoAnn Lindenfeld, Christopher M. O’Connor, and Javed Butler. “Reply: Improving Heart Failure Therapeutics: Thinking Outside the Pillbox?” Jacc Heart Fail 9, no. 4 (April 2021): 320–21. https://doi.org/10.1016/j.jchf.2021.01.005.
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• Blumer, Vanessa, Robert J. Mentz, Jie-Lena Sun, Javed Butler, Marco Metra, Adriaan A. Voors, Adrian F. Hernandez, Christopher M. O’Connor, and Stephen J. Greene. “Prognostic Role of Prior Heart Failure Hospitalization Among Patients Hospitalized for Worsening Chronic Heart Failure.” Circ Heart Fail 14, no. 4 (April 2021): e007871. https://doi.org/10.1161/CIRCHEARTFAILURE.120.007871.
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• O’Connor, Christopher M. “Heart Failure Leadership, Culture, and Governance: Lessons Learned From Tom Brady.” Jacc Heart Fail 9, no. 4 (April 2021): 317–18. https://doi.org/10.1016/j.jchf.2021.02.002.
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• Yang, Siyun, Monique Anderson Starks, Adrian F. Hernandez, Elizabeth L. Turner, Robert M. Califf, Christopher M. O’Connor, Robert J. Mentz, and Kingshuk Roy Choudhury. “Corrigendum to "Impact of baseline covariate imbalance on bias in treatment effect estimation in cluster randomized trials: Race as an example" [Contemporary Clinical Trials volume 88 (2020) 105775].” Contemp Clin Trials 103 (April 2021): 106298. https://doi.org/10.1016/j.cct.2021.106298.
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• Brooksbank, Jeremy A., Stephen J. Greene, Hailey M. Harris, Amanda Stebbins, Mona Fiuzat, David J. Whellan, Brooke Alhanti, et al. “Beta-blocker and ACE-inhibitor dosing as a function of body surface area: From the HF-ACTION trial.” Am Heart J 233 (March 2021): 1–4. https://doi.org/10.1016/j.ahj.2020.11.003.
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• Fudim, Marat, Joseph B. Lerman, Courtney Page, Brooke Alhanti, Robert M. Califf, Justin A. Ezekowitz, Nicolas Girerd, et al. “Plasma Volume Status and Its Association With In-Hospital and Postdischarge Outcomes in Decompensated Heart Failure.” J Card Fail 27, no. 3 (March 2021): 297–308. https://doi.org/10.1016/j.cardfail.2020.09.478.
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• O’Connor, Christopher M. “Reviewers Hall of Fame: 2020 Top Reviewers.” Jacc Heart Fail 9, no. 3 (March 2021): 241. https://doi.org/10.1016/j.jchf.2021.01.004.
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• Felker, G Michael, John J. V. McMurray, John G. Cleland, Christopher M. O’Connor, John R. Teerlink, Adriaan A. Voors, Jan Belohlavek, et al. “Effects of a Novel Nitroxyl Donor in Acute Heart Failure: The STAND-UP AHF Study.” Jacc Heart Fail 9, no. 2 (February 2021): 146–57. https://doi.org/10.1016/j.jchf.2020.10.012.
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• O’Connor, Christopher M. “Meet Me in the Middle: Lessons From the Cardiorenal Advisory Committee for Sacubitril/Valsartan in HFpEF.” Jacc Heart Fail 9, no. 2 (February 2021): 161–63. https://doi.org/10.1016/j.jchf.2020.12.003.
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• Bhatt, Ankeet S., William T. Abraham, JoAnn Lindenfeld, Michael Bristow, Peter E. Carson, G Michael Felker, Gregg C. Fonarow, et al. “Treatment of HF in an Era of Multiple Therapies: Statement From the HF Collaboratory.” Jacc Heart Fail 9, no. 1 (January 2021): 1–12. https://doi.org/10.1016/j.jchf.2020.10.014.
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• O’Connor, Christopher M. “A Generation Passed; A Generation Forward: Why Joseph C. Greenfield, Chairman of Medicine, Duke University, Matters Today (1931 to 2020).” Jacc Heart Fail 9, no. 1 (January 2021): 80–81. https://doi.org/10.1016/j.jchf.2020.11.005.
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• Abraham, William T., Mitchell A. Psotka, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Roxana Mehran, Amrut V. Ambardekar, et al. “Standardized definitions for evaluation of heart failure therapies: scientific expert panel from the Heart Failure Collaboratory and Academic Research Consortium.” Eur J Heart Fail 22, no. 12 (December 2020): 2175–86. https://doi.org/10.1002/ejhf.2018.
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• Sbolli, Marco, and Christopher M. O’Connor. “Aldosterone: Behind the Scenes of Depression and Heart Failure?” Jacc Heart Fail 8, no. 12 (December 2020): 1021–23. https://doi.org/10.1016/j.jchf.2020.10.006.
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• Angraal, Suveen, César Caraballo, Peter Kahn, Ambika Bhatnagar, Bikramjot Singh, F Perry Wilson, Mona Fiuzat, et al. “Geographical affiliation with top 10 NIH-funded academic medical centers and differences between mortality from cardiovascular disease and cancer.” Am Heart J 230 (December 2020): 54–58. https://doi.org/10.1016/j.ahj.2020.08.014.
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• Lanfear, David E., Jasmine A. Luzum, Ruicong She, Hongsheng Gui, Mark P. Donahue, Christopher M. O’Connor, Kirkwood F. Adams, et al. “Polygenic Score for β-Blocker Survival Benefit in European Ancestry Patients With Reduced Ejection Fraction Heart Failure.” Circ Heart Fail 13, no. 12 (December 2020): e007012. https://doi.org/10.1161/CIRCHEARTFAILURE.119.007012.
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• O’Connor, Christopher M., and Michael R. Bristow. “Changing U.S. Heart Failure Research Culture: Part 2-Recognizing Frontline Investigators and Coordinators.” Jacc Heart Fail 8, no. 12 (December 2020): 1050–51. https://doi.org/10.1016/j.jchf.2020.10.010.
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• Perego, Carlotta, Marco Sbolli, Claudia Specchia, Mona Fiuzat, Zachary R. McCaw, Marco Metra, Chiara Oriecuia, et al. “Utility of Restricted Mean Survival Time Analysis for Heart Failure Clinical Trial Evaluation and Interpretation.” Jacc Heart Fail 8, no. 12 (December 2020): 973–83. https://doi.org/10.1016/j.jchf.2020.07.005.
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• Psotka, Mitchell A., William T. Abraham, Mona Fiuzat, Gerasimos Filippatos, JoAnn Lindenfeld, Tariq Ahmad, Ankeet S. Bhatt, et al. “Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel.” J Am Coll Cardiol 76, no. 20 (November 17, 2020): 2368–78. https://doi.org/10.1016/j.jacc.2020.09.544.
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• O’Connor, Christopher M. “Personalized Therapeutic Approach: Gun Control for Shotgun Therapy.” Jacc Heart Fail 8, no. 11 (November 2020): 954–55. https://doi.org/10.1016/j.jchf.2020.09.002.
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• Ezekowitz, Justin A., Christopher M. O’Connor, Richard W. Troughton, Wendimagegn G. Alemayehu, Cynthia M. Westerhout, Adriaan A. Voors, Javed Butler, et al. “N-Terminal Pro-B-Type Natriuretic Peptide and Clinical Outcomes: Vericiguat Heart Failure With Reduced Ejection Fraction Study.” Jacc Heart Fail 8, no. 11 (November 2020): 931–39. https://doi.org/10.1016/j.jchf.2020.08.008.
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• Sbolli, Marco, Mona Fiuzat, Dario Cani, and Christopher M. O’Connor. “Depression and heart failure: the lonely comorbidity.” Eur J Heart Fail 22, no. 11 (November 2020): 2007–17. https://doi.org/10.1002/ejhf.1865.
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• Armstrong, Paul W., Carolyn S. P. Lam, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Burkert Pieske, et al. “Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial.” Jama 324, no. 15 (October 20, 2020): 1512–21. https://doi.org/10.1001/jama.2020.15922.
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• Armstrong, Paul W., Kevin J. Anstrom, Christopher M. O’Connor, and Christopher M. VICTORIA Study Group. “Vericiguat in Heart Failure with Reduced Ejection Fraction. Reply.” N Engl J Med 383, no. 15 (October 8, 2020): 1497–98. https://doi.org/10.1056/NEJMc2027731.
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• Psotka, Mitchell A., Mona Fiuzat, Marco Metra, and Christopher M. O’Connor. “Reply: Potential Mechanisms to Improve Heart Failure Clinical Trial Publication Rates.” J Am Coll Cardiol 76, no. 14 (October 6, 2020): 1717–18. https://doi.org/10.1016/j.jacc.2020.08.013.
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• Armstrong, Paul W., Burkert Pieske, and Christopher M. O’Connor. “Effects of vericiguat in heart failure with reduced ejection fraction: do not forget sST2. Reply.” Eur J Heart Fail 22, no. 10 (October 2020): 1935. https://doi.org/10.1002/ejhf.1765.
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• O’Connor, Christopher M. “Convalescence From COVID Research: Lessons From the Heart Failure Community.” Jacc Heart Fail 8, no. 10 (October 2020): 870–71. https://doi.org/10.1016/j.jchf.2020.08.005.
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• Carubelli, Valentina, Yuhui Zhang, Marco Metra, Carlo Lombardi, G Michael Felker, Gerasimos Filippatos, Christopher M. O’Connor, et al. “Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial.” Eur J Heart Fail 22, no. 9 (September 2020): 1684–93. https://doi.org/10.1002/ejhf.1743.
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• O’Connor, Christopher M., and Cleveland Francis. “The Journey of an American Black Cardiologist.” Jacc Heart Fail 8, no. 9 (September 2020): 780–81. https://doi.org/10.1016/j.jchf.2020.08.001.
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• Psotka, Mitchell A., Mona Fiuzat, Scott D. Solomon, Cynthia Chauhan, G Michael Felker, Javed Butler, John R. Teerlink, Shashank S. Sinha, Christopher M. O’Connor, and Marvin A. Konstam. “Challenges and Potential Improvements to Patient Access to Pharmaceuticals: Examples From Cardiology.” Circulation 142, no. 8 (August 25, 2020): 790–98. https://doi.org/10.1161/CIRCULATIONAHA.119.044976.
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• Abraham, William T., Mona Fiuzat, Mitchell A. Psotka, and Christopher M. O’Connor. “Heart Failure Collaboratory Statement on Remote Monitoring and Social Distancing in the Landscape of COVID-19.” Jacc Heart Fail 8, no. 8 (August 2020): 692–94. https://doi.org/10.1016/j.jchf.2020.06.006.
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• Damluji, Abdulla A., Michael Fabbro, Richard H. Epstein, Stefan Rayer, Ying Wang, Mauro Moscucci, Mauricio G. Cohen, et al. “Transcatheter Aortic Valve Replacement in Low-Population Density Areas: Assessing Healthcare Access for Older Adults With Severe Aortic Stenosis.” Circ Cardiovasc Qual Outcomes 13, no. 8 (August 2020): e006245. https://doi.org/10.1161/CIRCOUTCOMES.119.006245.
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• Reza, Nosheen, Ayman Samman Tahhan, Nadim Mahmud, Ersilia M. DeFilippis, Alaaeddin Alrohaibani, Muthiah Vaduganathan, Stephen J. Greene, et al. “Representation of Women Authors in International Heart Failure Guidelines and Contemporary Clinical Trials.” Circ Heart Fail 13, no. 8 (August 2020): e006605. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006605.
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• O’Connor, Christopher M. “COVID-19 Fatigue: Not So Fast.” Jacc Heart Fail 8, no. 7 (July 2020): 592–94. https://doi.org/10.1016/j.jchf.2020.06.001.
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• Fiuzat, Mona, Justin Ezekowitz, Wendimagegn Alemayehu, Cynthia M. Westerhout, Marco Sbolli, Dario Cani, David J. Whellan, et al. “Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial.” Jama Cardiol 5, no. 7 (July 1, 2020): 757–64. https://doi.org/10.1001/jamacardio.2020.0640.
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• Psotka, Mitchell A., Federica Latta, Dario Cani, Mona Fiuzat, Marco Sbolli, Scott Barnett, Marco Metra, and Christopher M. O’Connor. “Publication Rates of Heart Failure Clinical Trials Remain Low.” J Am Coll Cardiol 75, no. 25 (June 30, 2020): 3151–61. https://doi.org/10.1016/j.jacc.2020.04.068.
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• Bhatt, Ankeet S., Andrew P. Ambrosy, Allison Dunning, Adam D. DeVore, Javed Butler, Shelby Reed, Adriaan Voors, et al. “The burden of non-cardiac comorbidities and association with clinical outcomes in an acute heart failure trial - insights from ASCEND-HF.” Eur J Heart Fail 22, no. 6 (June 2020): 1022–31. https://doi.org/10.1002/ejhf.1795.
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• Damluji, Abdulla A., Gregory Rodriguez, Thomas Noel, Lakerria Davis, Vishal Dahya, Behnam Tehrani, Kelly Epps, et al. “Sarcopenia and health-related quality of life in older adults after transcatheter aortic valve replacement.” Am Heart J 224 (June 2020): 171–81. https://doi.org/10.1016/j.ahj.2020.03.021.
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• Fiuzat, Mona, Naomi Lowy, Norman Stockbridge, Marco Sbolli, Federica Latta, JoAnn Lindenfeld, Eldrin F. Lewis, et al. “Endpoints in Heart Failure Drug Development: History and Future.” Jacc Heart Fail 8, no. 6 (June 2020): 429–40. https://doi.org/10.1016/j.jchf.2019.12.011.
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• O’Connor, Christopher M. “Heart Failure Editorial Emergencies in the COVID-19 Era.” Jacc. Heart Failure 8, no. 6 (June 2020): 518. https://doi.org/10.1016/j.jchf.2020.04.002.
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• Armstrong, Paul W., Burkert Pieske, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Javed Butler, Carolyn S. P. Lam, et al. “Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.” N Engl J Med 382, no. 20 (May 14, 2020): 1883–93. https://doi.org/10.1056/NEJMoa1915928.
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• Reddy, Yogesh N. V., Barry A. Borlaug, Christopher M. O’Connor, and Bernard J. Gersh. “Novel approaches to the management of chronic systolic heart failure: future directions and unanswered questions.” Eur Heart J 41, no. 18 (May 7, 2020): 1764–74. https://doi.org/10.1093/eurheartj/ehz364.
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• Cooper, Lauren B., Mitchell A. Psotka, Shashank Sinha, Brahmajee K. Nallamothu, Christopher R. deFilippi, Wayne Batchelor, Christopher M. O’Connor, and Abdulla A. Damluji. “Specificity of administrative coding for older adults with acute heart failure hospitalizations.” Am Heart J 223 (May 2020): 1–2. https://doi.org/10.1016/j.ahj.2020.02.004.
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• Abraham, William T., Mona Fiuzat, Mitchell A. Psotka, and Christopher M. O’Connor. “Heart Failure Collaboratory Statement on Clinical Trials in the Landscape of COVID-19.” Jacc Heart Fail 8, no. 5 (May 2020): 423–25. https://doi.org/10.1016/j.jchf.2020.03.005.
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• Butler, Javed, Muhammad Shahzeb Khan, Stefan D. Anker, Gregg C. Fonarow, Raymond J. Kim, Savina Nodari, Christopher M. O’Connor, et al. “Effects of Elamipretide on Left Ventricular Function in Patients With Heart Failure With Reduced Ejection Fraction: The PROGRESS-HF Phase 2 Trial.” J Card Fail 26, no. 5 (May 2020): 429–37. https://doi.org/10.1016/j.cardfail.2020.02.001.
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• Ibrahim, Nasrien E., John C. Burnett, Javed Butler, Alexander Camacho, G Michael Felker, Mona Fiuzat, Christopher O’Connor, et al. “Natriuretic Peptides as Inclusion Criteria in Clinical Trials: A JACC: Heart Failure Position Paper.” Jacc Heart Fail 8, no. 5 (May 2020): 347–58. https://doi.org/10.1016/j.jchf.2019.12.010.
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• Pandhi, Paloma, Jozine M. Ter Maaten, Johanna E. Emmens, Joachim Struck, Andreas Bergmann, John G. Cleland, Michael M. Givertz, et al. “Clinical value of pre-discharge bio-adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission.” Eur J Heart Fail 22, no. 4 (April 2020): 683–91. https://doi.org/10.1002/ejhf.1693.
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• Bilchick, Kenneth C., Yongfei Wang, Jeptha P. Curtis, Alan Cheng, Kumar Dharmarajan, Ramin Shadman, Todd F. Dardas, et al. “Modeling defibrillation benefit for survival among cardiac resynchronization therapy defibrillator recipients.” Am Heart J 222 (April 2020): 93–104. https://doi.org/10.1016/j.ahj.2019.12.017.
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• O’Connor, Christopher M. “Heart Failure Multidisciplinary Teams and New Zealand Rugby: What Can We Learn From the "All Blacks" Rugby Team?” Jacc Heart Fail 8, no. 4 (April 2020): 341–42. https://doi.org/10.1016/j.jchf.2020.02.003.
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• Truby, Lauren K., Christopher O’Connor, Mona Fiuzat, Amanda Stebbins, Adrian Coles, Chetan B. Patel, Bradi Granger, et al. “Sex Differences in Quality of Life and Clinical Outcomes in Patients With Advanced Heart Failure: Insights From the PAL-HF Trial.” Circ Heart Fail 13, no. 4 (April 2020): e006134. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006134.
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• O’Connor, Christopher M. “Suicide in HF Patients: A Call for Recognition.” Jacc Heart Fail 8, no. 3 (March 2020): 243–44. https://doi.org/10.1016/j.jchf.2020.01.008.
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• O’Connor, Christopher M. “Open Access in Heart Failure: Ready or Not, Here We Come.” Jacc Heart Fail 8, no. 2 (February 2020): 151–52. https://doi.org/10.1016/j.jchf.2020.01.001.
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• O’Connor, Christopher M. “The Heart Failure High Five: Medical Therapy and Policy: 2019.” Jacc Heart Fail 8, no. 1 (January 2020): 81–82. https://doi.org/10.1016/j.jchf.2019.11.008.
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• Psotka, Mitchell A., Gregg C. Fonarow, Larry A. Allen, Karen E. Joynt Maddox, Mona Fiuzat, Paul Heidenreich, Adrian F. Hernandez, Marvin A. Konstam, Clyde W. Yancy, and Christopher M. O’Connor. “The Hospital Readmissions Reduction Program: Nationwide Perspectives and Recommendations: A JACC: Heart Failure Position Paper.” Jacc Heart Fail 8, no. 1 (January 2020): 1–11. https://doi.org/10.1016/j.jchf.2019.07.012.
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• Yang, Siyun, Monique Anderson Starks, Adrian F. Hernandez, Elizabeth L. Turner, Robert M. Califf, Christopher M. O’Connor, Robert J. Mentz, and Kingshuk Roy Choudhury. “Impact of baseline covariate imbalance on bias in treatment effect estimation in cluster randomized trials: Race as an example.” Contemp Clin Trials 88 (January 2020): 105775. https://doi.org/10.1016/j.cct.2019.04.016.
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• Butler, Javed, Milton Packer, Stephen J. Greene, Mona Fiuzat, Stefan D. Anker, Kevin J. Anstrom, Peter E. Carson, et al. “Heart Failure End Points in Cardiovascular Outcome Trials of Sodium Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Critical Evaluation of Clinical and Regulatory Issues.” Circulation 140, no. 25 (December 17, 2019): 2108–18. https://doi.org/10.1161/CIRCULATIONAHA.119.042155.
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• Caraballo, César, Nihar R. Desai, Hillary Mulder, Brooke Alhanti, F Perry Wilson, Mona Fiuzat, G Michael Felker, et al. “Clinical Implications of the New York Heart Association Classification.” J Am Heart Assoc 8, no. 23 (December 3, 2019): e014240. https://doi.org/10.1161/JAHA.119.014240.
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• O’Connor, Christopher M. “N-1 and Sequencing Clinical Heart Failure Trials: Charting the Path for Future Clinical Care.” Jacc Heart Fail 7, no. 12 (December 2019): 1089–90. https://doi.org/10.1016/j.jchf.2019.10.006.
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• DeVore, Adam D., Eric Yow, Mitchell W. Krucoff, Matthew W. Sherwood, Linda K. Shaw, Karen Chiswell, Christopher M. O’Connor, Erik Magnus Ohman, and Eric J. Velazquez. “Percutaneous coronary intervention outcomes in patients with stable coronary disease and left ventricular systolic dysfunction.” Esc Heart Fail 6, no. 6 (December 2019): 1233–42. https://doi.org/10.1002/ehf2.12510.
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• Pieske, Burkert, Mahesh J. Patel, Cynthia M. Westerhout, Kevin J. Anstrom, Javed Butler, Justin Ezekowitz, Adrian F. Hernandez, et al. “Baseline features of the VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction) trial.” Eur J Heart Fail 21, no. 12 (December 2019): 1596–1604. https://doi.org/10.1002/ejhf.1664.
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• Regan, Jessica A., Dalane W. Kitzman, Eric S. Leifer, William E. Kraus, Jerome L. Fleg, Daniel E. Forman, David J. Whellan, et al. “Impact of Age on Comorbidities and Outcomes in Heart Failure With Reduced Ejection Fraction.” Jacc Heart Fail 7, no. 12 (December 2019): 1056–65. https://doi.org/10.1016/j.jchf.2019.09.004.
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• O’Connor, Christopher M. “A Call for Change: Level of Statistical Significance.” Jacc Heart Fail 7, no. 11 (November 2019): 993–94. https://doi.org/10.1016/j.jchf.2019.09.005.
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• Truesdell, Alexander G., Behnam Tehrani, Carolyn Rosner, Ramesh Singh, Shashank Sinha, Mehul Desai, Shashank Desai, et al. “After Action Reviews.” J Invasive Cardiol 31, no. 11 (November 2019): E341.
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• Beldhuis, Iris E., Koen W. Streng, Peter van der Meer, Jozine M. Ter Maaten, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, et al. “Trajectories of Changes in Renal Function in Patients with Acute Heart Failure.” J Card Fail 25, no. 11 (November 2019): 866–74. https://doi.org/10.1016/j.cardfail.2019.07.004.
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• Beusekamp, Joost C., Jasper Tromp, John G. F. Cleland, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, John R. Teerlink, et al. “Hyperkalemia and Treatment With RAAS Inhibitors During Acute Heart Failure Hospitalizations and Their Association With Mortality.” Jacc Heart Fail 7, no. 11 (November 2019): 970–79. https://doi.org/10.1016/j.jchf.2019.07.010.
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• Greene, Stephen J., Adam D. DeVore, Shubin Sheng, Gregg C. Fonarow, Javed Butler, Robert M. Califf, Adrian F. Hernandez, et al. “Representativeness of a Heart Failure Trial by Race and Sex: Results From ASCEND-HF and GWTG-HF.” Jacc Heart Fail 7, no. 11 (November 2019): 980–92. https://doi.org/10.1016/j.jchf.2019.07.011.
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• Psotka, Mitchell A., Mona Fiuzat, Peter E. Carson, David P. Kao, Jeffrey Cerkvenik, Daniel E. Schaber, Patrick Verta, et al. “Design of a "Lean" Case Report Form for Heart Failure Therapeutic Development.” Jacc Heart Fail 7, no. 11 (November 2019): 913–21. https://doi.org/10.1016/j.jchf.2019.07.001.
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• O’Connor, Christopher M. “Acute Decompensated Heart Failure: Is There a Path Forward?” Jacc Heart Fail 7, no. 10 (October 2019): 911–12. https://doi.org/10.1016/j.jchf.2019.08.005.
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• Januzzi, James L., Tariq Ahmad, Hillary Mulder, Adrian Coles, Kevin J. Anstrom, Kirkwood F. Adams, Justin A. Ezekowitz, et al. “Natriuretic Peptide Response and Outcomes in Chronic Heart Failure With Reduced Ejection Fraction.” J Am Coll Cardiol 74, no. 9 (September 3, 2019): 1205–17. https://doi.org/10.1016/j.jacc.2019.06.055.
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• O’Connor, Christopher M. “Heart Failure Physician Burnout: How Can We Help?” Jacc Heart Fail 7, no. 9 (September 2019): 821. https://doi.org/10.1016/j.jchf.2019.07.004.
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• Grodin, Justin L., Max J. Liebo, Javed Butler, Marco Metra, G Michael Felker, Adrian F. Hernandez, Adriaan A. Voors, et al. “Prognostic Implications of Changes in Amino-Terminal Pro-B-Type Natriuretic Peptide in Acute Decompensated Heart Failure: Insights From ASCEND-HF.” J Card Fail 25, no. 9 (September 2019): 703–11. https://doi.org/10.1016/j.cardfail.2019.04.002.
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• O’Connor, Christopher M. “Why Should We Publish All Clinical Trials?” Jacc Heart Fail 7, no. 8 (August 2019): 730. https://doi.org/10.1016/j.jchf.2019.06.009.
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• Felker, G Michael, Maria Borentain, John G. Cleland, Mary M. DeSouza, Paul D. Kessler, Christopher M. O’Connor, Dietmar Seiffert, John R. Teerlink, Adriaan A. Voors, and John J. V. McMurray. “Rationale and design for the development of a novel nitroxyl donor in patients with acute heart failure.” Eur J Heart Fail 21, no. 8 (August 2019): 1022–31. https://doi.org/10.1002/ejhf.1504.
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• Warraich, Haider J., Christopher M. O’Connor, Hongqiu Yang, Bradi B. Granger, Kimberly S. Johnson, Daniel B. Mark, Kevin J. Anstrom, et al. “African Americans With Advanced Heart Failure Are More Likely to Die in a Health Care Facility Than at Home or in Hospice: An Analysis From the PAL-HF Trial.” J Card Fail 25, no. 8 (August 2019): 693–94. https://doi.org/10.1016/j.cardfail.2019.05.013.
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• Tehrani, Behnam N., and Christopher M. O’Connor. “Reply: Standardized and Tailored Approach to Therapies for Cardiogenic Shock.” J Am Coll Cardiol 74, no. 4 (July 30, 2019): 593–94. https://doi.org/10.1016/j.jacc.2019.05.039.
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• O’Connor, Christopher M. “N-of-1 Clinical Trials.” Jacc Heart Fail 7, no. 7 (July 2019): 630–31. https://doi.org/10.1016/j.jchf.2019.05.004.
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• O’Connor, Christopher M. “Better Quality of Life Over More Quantity of Life: How We View Time Trade-Off.” Jacc Heart Fail 7, no. 6 (June 2019): 531–32. https://doi.org/10.1016/j.jchf.2019.05.001.
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• Ambrosy, Andrew P., Robert J. Mentz, Mona Fiuzat, John G. F. Cleland, Stephen J. Greene, Christopher M. O’Connor, John R. Teerlink, Faiez Zannad, and Scott D. Solomon. “Erratum to 'The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions' [Eur J Heart Fail 2018;20:963-972].” Eur J Heart Fail 21, no. 6 (June 2019): 819. https://doi.org/10.1002/ejhf.1480.
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• Blumenthal, James A., Yidan Zhu, Gary G. Koch, Patrick J. Smith, Lana L. Watkins, Alan L. Hinderliter, Benson M. Hoffman, et al. “The modifying effects of social support on psychological outcomes in patients with heart failure.” Health Psychol 38, no. 6 (June 2019): 502–8. https://doi.org/10.1037/hea0000716.
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• O’Connor, Christopher, Mona Fiuzat, Hillary Mulder, Adrian Coles, Tariq Ahmad, Justin A. Ezekowitz, Kirkwood F. Adams, et al. “Clinical factors related to morbidity and mortality in high-risk heart failure patients: the GUIDE-IT predictive model and risk score.” Eur J Heart Fail 21, no. 6 (June 2019): 770–78. https://doi.org/10.1002/ejhf.1450.
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• O’Connor, Christopher M. “Guideline-Directed Medical Therapy Clinics: A Call to Action for the Heart Failure Team.” Jacc Heart Fail 7, no. 5 (May 2019): 442–43. https://doi.org/10.1016/j.jchf.2019.04.001.
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• Butler, Javed, Carolyn S. P. Lam, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez, Christopher M. O’Connor, Burkert Pieske, et al. “Rationale and Design of the VITALITY-HFpEF Trial.” Circ Heart Fail 12, no. 5 (May 2019): e005998. https://doi.org/10.1161/CIRCHEARTFAILURE.119.005998.
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• Psotka, Mitchell A., Susan E. Ammon, Mona Fiuzat, Biykem Bozkurt, Eugene S. Chung, Robert T. Cole, Stephen J. Greene, et al. “Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey.” Jacc Heart Fail 7, no. 5 (May 2019): 431–38. https://doi.org/10.1016/j.jchf.2019.02.008.
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• Taylor, Rod S., Sarah Walker, Neil A. Smart, Massimo F. Piepoli, Fiona C. Warren, Oriana Ciani, David Whellan, et al. “Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis.” J Am Coll Cardiol 73, no. 12 (April 2, 2019): 1430–43. https://doi.org/10.1016/j.jacc.2018.12.072.
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• O’Connor, Christopher M. “Heart Failure Fake News: How Do We Distinguish the Truth?” Jacc Heart Fail 7, no. 4 (April 2019): 363. https://doi.org/10.1016/j.jchf.2019.02.004.
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• Lindenfeld, JoAnn, and Christopher M. O’Connor. “Heart Failure in Women.” Jacc Heart Fail 7, no. 3 (March 2019): 274–75. https://doi.org/10.1016/j.jchf.2019.01.012.
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• Vaduganathan, Muthiah, Ayman Samman Tahhan, Alaaeddin Alrohaibani, Stephen J. Greene, Gregg C. Fonarow, Orly Vardeny, JoAnn Lindenfeld, et al. “Do Women and Men Respond Similarly to Therapies in Contemporary Heart Failure Clinical Trials?” Jacc Heart Fail 7, no. 3 (March 2019): 267–71. https://doi.org/10.1016/j.jchf.2018.12.016.
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• O’Connor, Christopher M. “Recognizing Heart Failure Awareness Week.” Jacc Heart Fail 7, no. 2 (February 2019): 173. https://doi.org/10.1016/j.jchf.2018.12.013.
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• Daubert, Melissa A., Kirkwood Adams, Eric Yow, Huiman X. Barnhart, Pamela S. Douglas, Susan Rimmer, Casey Norris, et al. “NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF.” Jacc Heart Fail 7, no. 2 (February 2019): 158–68. https://doi.org/10.1016/j.jchf.2018.10.014.
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• O’Connor, Christopher M. “JACC: Heart Failure Peer Review Hall of Fame 2018.” Jacc Heart Fail 7, no. 1 (January 2019): 81. https://doi.org/10.1016/j.jchf.2018.12.001.
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• Luo, Nancy, Christopher M. O’Connor, Lauren B. Cooper, Jie-Lena Sun, Adrian Coles, Shelby D. Reed, David J. Whellan, Ileana L. Piña, William E. Kraus, and Robert J. Mentz. “Relationship between changing patient-reported outcomes and subsequent clinical events in patients with chronic heart failure: insights from HF-ACTION.” Eur J Heart Fail 21, no. 1 (January 2019): 63–70. https://doi.org/10.1002/ejhf.1299.
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• Piccini, Jonathan P., Sean D. Pokorney, Kevin J. Anstrom, Olaf Oldenburg, Naresh M. Punjabi, Mona Fiuzat, Gudaye Tasissa, et al. “Adaptive servo-ventilation reduces atrial fibrillation burden in patients with heart failure and sleep apnea.” Heart Rhythm 16, no. 1 (January 2019): 91–97. https://doi.org/10.1016/j.hrthm.2018.07.027.
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• Russell, Frances M., Robert R. Ehrman, Robinson Ferre, Luna Gargani, Vicki Noble, Jordan Rupp, Sean P. Collins, et al. “Design and rationale of the B-lines lung ultrasound guided emergency department management of acute heart failure (BLUSHED-AHF) pilot trial.” Heart Lung 48, no. 3 (2019): 186–92. https://doi.org/10.1016/j.hrtlng.2018.10.027.
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• O’Connor, Christopher M. “Aviation Emergencies for Heart Failure Cardiologists: A New Twist to the Heart Team.” Jacc Heart Fail 6, no. 12 (December 2018): 1047–48. https://doi.org/10.1016/j.jchf.2018.10.018.
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• Taylor, Rod S., Sarah Walker, Neil A. Smart, Massimo F. Piepoli, Fiona C. Warren, Oriana Ciani, Christopher O’Connor, et al. “Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials.” Eur J Heart Fail 20, no. 12 (December 2018): 1735–43. https://doi.org/10.1002/ejhf.1311.
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• Mark, Daniel B., Patricia A. Cowper, Kevin J. Anstrom, Shubin Sheng, Melanie R. Daniels, J David Knight, Khaula N. Baloch, et al. “Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure.” J Am Coll Cardiol 72, no. 21 (November 27, 2018): 2551–62. https://doi.org/10.1016/j.jacc.2018.08.2184.
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• O’Connor, Christopher M. “COAPTing Heart Failure Physicians, Interventional Cardiologists, and CardioThoracic Surgeons: A New Opportunity for Patients.” Jacc Heart Fail 6, no. 11 (November 2018): 967–68. https://doi.org/10.1016/j.jchf.2018.09.007.
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• Fudim, Marat, Christopher M. O’Connor, Hillary Mulder, Adrian Coles, Ankeet S. Bhatt, Andrew P. Ambrosy, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Loop diuretic adjustments in patients with chronic heart failure: Insights from HF-ACTION.” Am Heart J 205 (November 2018): 133–41. https://doi.org/10.1016/j.ahj.2018.06.017.
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• Fudim, Marat, Kishan S. Parikh, Allison Dunning, Adam D. DeVore, Robert J. Mentz, Phillip J. Schulte, Paul W. Armstrong, et al. “Relation of Volume Overload to Clinical Outcomes in Acute Heart Failure (From ASCEND-HF).” Am J Cardiol 122, no. 9 (November 1, 2018): 1506–12. https://doi.org/10.1016/j.amjcard.2018.07.023.
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• Hamo, Carine E., Christopher O’Connor, Marco Metra, James E. Udelson, Mihai Gheorghiade, and Javed Butler. “A Critical Appraisal of Short-Term End Points in Acute Heart Failure Clinical Trials.” J Card Fail 24, no. 11 (November 2018): 783–92. https://doi.org/10.1016/j.cardfail.2018.08.007.
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• Fudim, Marat, Rahul Loungani, Shannon M. Doerfler, Adrian Coles, Stephen J. Greene, Lauren B. Cooper, Mona Fiuzat, Christopher M. O’Connor, Joseph G. Rogers, and Robert J. Mentz. “Worsening renal function during decongestion among patients hospitalized for heart failure: Findings from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial.” Am Heart J 204 (October 2018): 163–73. https://doi.org/10.1016/j.ahj.2018.07.019.
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• Greene, Stephen J., Adrian F. Hernandez, Jie-Lena Sun, Javed Butler, Paul W. Armstrong, Justin A. Ezekowitz, Faiez Zannad, et al. “Relationship Between Enrolling Country Income Level and Patient Profile, Protocol Completion, and Trial End Points.” Circ Cardiovasc Qual Outcomes 11, no. 10 (October 2018): e004783. https://doi.org/10.1161/CIRCOUTCOMES.118.004783.
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• Jiang, Wei, David J. Whellan, Kirkwood F. Adams, Michael A. Babyak, Stephen H. Boyle, Jennifer L. Wilson, Chetan B. Patel, Joseph G. Rogers, William S. Harris, and Christopher M. O’Connor. “Long-Chain Omega-3 Fatty Acid Supplements in Depressed Heart Failure Patients: Results of the OCEAN Trial.” Jacc Heart Fail 6, no. 10 (October 2018): 833–43. https://doi.org/10.1016/j.jchf.2018.03.011.
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• O’Connor, Christopher M. “Depression in Heart Failure: Beyond a SADHART.” Jacc Heart Fail 6, no. 10 (October 2018): 885–86. https://doi.org/10.1016/j.jchf.2018.08.004.
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• Sharma, Abhinav, Lauren B. Cooper, Mona Fiuzat, Robert J. Mentz, João Pedro Ferreira, Javed Butler, David Fitchett, Alan Charles Moses, Christopher O’Connor, and Faiez Zannad. “Antihyperglycemic Therapies to Treat Patients With Heart Failure and Diabetes Mellitus.” Jacc Heart Fail 6, no. 10 (October 2018): 813–22. https://doi.org/10.1016/j.jchf.2018.05.020.
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• Tahhan, Ayman Samman, Muthiah Vaduganathan, Stephen J. Greene, Gregg C. Fonarow, Mona Fiuzat, Mariell Jessup, JoAnn Lindenfeld, Christopher M. O’Connor, and Javed Butler. “Enrollment of Older Patients, Women, and Racial and Ethnic Minorities in Contemporary Heart Failure Clinical Trials: A Systematic Review.” Jama Cardiol 3, no. 10 (October 1, 2018): 1011–19. https://doi.org/10.1001/jamacardio.2018.2559.
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• Ambrosy, Andrew P., Hillary Mulder, Adrian Coles, William E. Krauss, Carolyn S. P. Lam, Peter A. McCullough, Ileana Pina, et al. “Renal Function and Exercise Training in AmbulatoryHeart Failure Patients With a Reduced Ejection Fraction.” Am J Cardiol 122, no. 6 (September 15, 2018): 999–1007. https://doi.org/10.1016/j.amjcard.2018.06.011.
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• Greene, Stephen J., Robert J. Mentz, Mona Fiuzat, Javed Butler, Scott D. Solomon, Andrew P. Ambrosy, Cyrus Mehta, John R. Teerlink, Faiez Zannad, and Christopher M. O’Connor. “Reassessing the Role of Surrogate End Points in Drug Development for Heart Failure.” Circulation 138, no. 10 (September 4, 2018): 1039–53. https://doi.org/10.1161/CIRCULATIONAHA.118.034668.
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• Cooper, Lauren B., Jonathan Yap, Wan Ting Tay, Tiew-Hwa K. Teng, Michael MacDonald, Inder S. Anand, Abhinav Sharma, et al. “Multi-ethnic comparisons of diabetes in heart failure with reduced ejection fraction: insights from the HF-ACTION trial and the ASIAN-HF registry.” Eur J Heart Fail 20, no. 9 (September 2018): 1281–89. https://doi.org/10.1002/ejhf.1223.
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• O’Connor, Christopher M. “Politically Correct Heart Failure Research in America to Avoid Geographic Variation.” Jacc Heart Fail 6, no. 9 (September 2018): 805–6. https://doi.org/10.1016/j.jchf.2018.07.010.
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• Grodin, Justin L., Javed Butler, Marco Metra, G Michael Felker, Adriaan A. Voors, John J. McMurray, Paul W. Armstrong, et al. “Circulating Cardiac Troponin I Levels Measured by a Novel Highly Sensitive Assay in Acute Decompensated Heart Failure: Insights From the ASCEND-HF Trial.” J Card Fail 24, no. 8 (August 2018): 512–19. https://doi.org/10.1016/j.cardfail.2018.06.008.
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• O’Connor, Christopher M. “HFpEF: From Early Observations to Worldwide Awareness.” Jacc Heart Fail 6, no. 8 (August 2018): 718–19. https://doi.org/10.1016/j.jchf.2018.07.001.
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• Parikh, Kishan S., Kavita Sharma, Mona Fiuzat, Howard K. Surks, Jyothis T. George, Narimon Honarpour, Christopher Depre, et al. “Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials.” Jacc Heart Fail 6, no. 8 (August 2018): 619–32. https://doi.org/10.1016/j.jchf.2018.06.008.
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• Parikh, Kishan S., Mona Fiuzat, Gordon Davis, Megan Neely, Penny Blain-Nelson, David J. Whellan, William T. Abraham, et al. “Dose Response of β-Blockers in Adrenergic Receptor Polymorphism Genotypes.” Circ Genom Precis Med 11, no. 8 (August 2018): e002210. https://doi.org/10.1161/CIRCGEN.117.002210.
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• Vaduganathan, Muthiah, Ravi B. Patel, Robert J. Mentz, Haris Subacius, Neal A. Chatterjee, Stephen J. Greene, Andrew P. Ambrosy, et al. “Sudden Death After Hospitalization for Heart Failure With Reduced Ejection Fraction (from the EVEREST Trial).” Am J Cardiol 122, no. 2 (July 15, 2018): 255–60. https://doi.org/10.1016/j.amjcard.2018.03.362.
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• Daubert, Melissa A., David J. Whellan, Holger Woehrle, Gudaye Tasissa, Kevin J. Anstrom, JoAnn Lindenfeld, Adam Benjafield, et al. “Treatment of sleep-disordered breathing in heart failure impacts cardiac remodeling: Insights from the CAT-HF Trial.” Am Heart J 201 (July 2018): 40–48. https://doi.org/10.1016/j.ahj.2018.03.026.
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• O’Connor, Christopher M. “Cardiovascular Drug Pricing: Less Innovation for More Access?” Jacc Heart Fail 6, no. 7 (July 2018): 613–14. https://doi.org/10.1016/j.jchf.2018.05.016.
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• Warraich, Haider J., Christopher O’Connor, Angie Wu, Adrian Coles, William E. Kraus, Ileana L. Piña, David J. Whellan, and Robert J. Mentz. “Differences Between Patients Enrolled Early and Late During Clinical Trial Recruitment: Insights From the HF-ACTION Trial.” Circ Cardiovasc Qual Outcomes 11, no. 7 (July 2018): e004643. https://doi.org/10.1161/CIRCOUTCOMES.117.004643.
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• O’Connor, Christopher M. “Dying With Dignity and Heart Failure: A Lesson From Barbara Bush.” Jacc Heart Fail 6, no. 6 (June 2018): 536–37. https://doi.org/10.1016/j.jchf.2018.04.011.
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• Ambrosy, Andrew P., Robert J. Mentz, Mona Fiuzat, John G. F. Cleland, Stephen J. Greene, Christopher M. O’Connor, John R. Teerlink, Faiez Zannad, and Scott D. Solomon. “The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions.” Eur J Heart Fail 20, no. 6 (June 2018): 963–72. https://doi.org/10.1002/ejhf.1159.
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• Ahmad, Tariq, Keyanna Jackson, Veena S. Rao, WH Wilson Tang, Meredith A. Brisco-Bacik, Horng H. Chen, G Michael Felker, et al. “Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury.” Circulation 137, no. 19 (May 8, 2018): 2016–28. https://doi.org/10.1161/CIRCULATIONAHA.117.030112.
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• Rubio-Gracia, Jorge, Biniyam G. Demissei, Jozine M. Ter Maaten, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, et al. “Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure.” Int J Cardiol 258 (May 1, 2018): 185–91. https://doi.org/10.1016/j.ijcard.2018.01.067.
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• Ambrosy, Andrew P., Ankeet S. Bhatt, Amanda L. Stebbins, Lisa M. Wruck, Marat Fudim, Stephen J. Greene, William E. Kraus, et al. “Prevalent digoxin use and subsequent risk of death or hospitalization in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) randomized controlled trial.” Am Heart J 199 (May 2018): 97–104. https://doi.org/10.1016/j.ahj.2018.02.004.
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• Metra, Marco, Gad Cotter, Stefanie Senger, Christopher Edwards, John G. Cleland, Piotr Ponikowski, Guillermo C. Cursack, et al. “Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data.” Circ Heart Fail 11, no. 5 (May 2018): e004644. https://doi.org/10.1161/CIRCHEARTFAILURE.117.004644.
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• O’Connor, Christopher M. “What's One More Day?” Jacc Heart Fail 6, no. 5 (May 2018): 438. https://doi.org/10.1016/j.jchf.2018.03.015.
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• Ahmad, Tariq, Lars H. Lund, Pooja Rao, Rohit Ghosh, Prashant Warier, Benjamin Vaccaro, Ulf Dahlström, Christopher M. O’Connor, G Michael Felker, and Nihar R. Desai. “Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients.” J Am Heart Assoc 7, no. 8 (April 12, 2018). https://doi.org/10.1161/JAHA.117.008081.
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• O’Connor, Christopher M., and Michael R. Bristow. “Changing the Research Culture in the United States.” Jacc Heart Fail 6, no. 4 (April 2018): 344–45. https://doi.org/10.1016/j.jchf.2018.03.001.
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• Cerbin, Lukasz P., Andrew P. Ambrosy, Stephen J. Greene, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, et al. “Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial.” Jacc Heart Fail 6, no. 4 (April 2018): 298–307. https://doi.org/10.1016/j.jchf.2018.01.018.
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• Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.” J Am Coll Cardiol 71, no. 9 (March 6, 2018): 1021–34. https://doi.org/10.1016/j.jacc.2017.12.048.
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• O’Connor, Christopher M. “Heart Failure Health Care 2018: Challenges and Opportunities.” Jacc Heart Fail 6, no. 3 (March 2018): 262–63. https://doi.org/10.1016/j.jchf.2018.01.013.
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• Hicks, Karen A., Kenneth W. Mahaffey, Roxana Mehran, Steven E. Nissen, Stephen D. Wiviott, Billy Dunn, Scott D. Solomon, et al. “2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.” Circulation 137, no. 9 (February 27, 2018): 961–72. https://doi.org/10.1161/CIRCULATIONAHA.117.033502.
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• Bhatt, Ankeet S., Lauren B. Cooper, Andrew P. Ambrosy, Robert M. Clare, Adrian Coles, Emer Joyce, Arun Krishnamoorthy, et al. “Interaction of Body Mass Index on the Association Between N-Terminal-Pro-b-Type Natriuretic Peptide and Morbidity and Mortality in Patients With Acute Heart Failure: Findings From ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” J Am Heart Assoc 7, no. 3 (February 3, 2018). https://doi.org/10.1161/JAHA.117.006740.
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• Armstrong, Paul W., Lothar Roessig, Mahesh J. Patel, Kevin J. Anstrom, Javed Butler, Adriaan A. Voors, Carolyn S. P. Lam, et al. “A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Efficacy and Safety of the Oral Soluble Guanylate Cyclase Stimulator: The VICTORIA Trial.” Jacc Heart Fail 6, no. 2 (February 2018): 96–104. https://doi.org/10.1016/j.jchf.2017.08.013.
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• Cotter, Gad, Marco Metra, Beth A. Davison, Guillaume Jondeau, John G. F. Cleland, Robert C. Bourge, Olga Milo, et al. “Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe?” Eur J Heart Fail 20, no. 2 (February 2018): 317–22. https://doi.org/10.1002/ejhf.889.
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• Fudim, Marat, Christopher M. O’Connor, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Adrian Coles, Justin A. Ezekowitz, et al. “Aetiology, timing and clinical predictors of early vs. late readmission following index hospitalization for acute heart failure: insights from ASCEND-HF.” Eur J Heart Fail 20, no. 2 (February 2018): 304–14. https://doi.org/10.1002/ejhf.1020.
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• O’Connor, Christopher M. “Smartphone, Mom, and HFpEF.” Jacc Heart Fail 6, no. 2 (February 2018): 176. https://doi.org/10.1016/j.jchf.2017.12.010.
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• O’Connor, Christopher M., Mitchell A. Psotka, Mona Fiuzat, JoAnn Lindenfeld, William T. Abraham, Michael R. Bristow, Daniel Canos, et al. “Improving Heart Failure Therapeutics Development in the United States: The Heart Failure Collaboratory.” J Am Coll Cardiol 71, no. 4 (January 30, 2018): 443–53. https://doi.org/10.1016/j.jacc.2017.11.048.
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• O’Connor, Christopher M. “I Don't Care How Low My BNP Is, I Want to Feel Good.” Jacc Heart Fail 6, no. 1 (January 2018): 82–83. https://doi.org/10.1016/j.jchf.2017.11.004.
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• Pastva, Amy M., Pamela W. Duncan, Gordon R. Reeves, M Benjamin Nelson, David J. Whellan, Christopher M. O’Connor, Joel D. Eggebeen, et al. “Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial.” Contemp Clin Trials 64 (January 2018): 118–27. https://doi.org/10.1016/j.cct.2017.10.014.
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• Daubert, Melissa A., Eric Yow, Gary Dunn, Sotir Marchev, Huiman Barnhart, Pamela S. Douglas, Christopher O’Connor, Sidney Goldstein, James E. Udelson, and Hani N. Sabbah. “Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide.” Circ Heart Fail 10, no. 12 (December 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.117.004389.
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• Alenezi, Fawaz, Beverly H. Brummett, Stephen H. Boyle, Zainab Samad, Michael A. Babyak, Nabil Alzaeim, Jennifer Wilson, et al. “Usefulness of Myocardial Annular Velocity Change During Mental Stress to Predict Cardiovascular Outcome in Patients With Coronary Artery Disease (From the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment Trial).” Am J Cardiol 120, no. 9 (November 1, 2017): 1495–1500. https://doi.org/10.1016/j.amjcard.2017.07.039.
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• O’Connor, Christopher M. “Goodbye Mihai: We Will Miss You.” Jacc Heart Fail 5, no. 11 (November 2017): 848–49. https://doi.org/10.1016/j.jchf.2017.09.007.
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• O’Connor, Christopher M. “Q&A With the JACC: Heart Failure Editor-in-Chief: Marking the 5-Year Milestone.” Jacc Heart Fail 5, no. 10 (October 2017): 758–59. https://doi.org/10.1016/j.jchf.2017.08.006.
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• Sharma, Abhinav, Biniyam G. Demissei, Jasper Tromp, Hans L. Hillege, John G. Cleland, Christopher M. O’Connor, Marco Metra, et al. “A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure.” Eur J Heart Fail 19, no. 10 (October 2017): 1310–20. https://doi.org/10.1002/ejhf.912.
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• Sharma, Abhinav, Susanna R. Stevens, Joseph Lucas, Mona Fiuzat, Kirkwood F. Adams, David J. Whellan, Mark P. Donahue, et al. “Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study.” Jacc Heart Fail 5, no. 10 (October 2017): 724–34. https://doi.org/10.1016/j.jchf.2017.07.013.
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• Luo, Nancy, Tiew-Hwa Katherine Teng, Wan Ting Tay, Inder S. Anand, William E. Kraus, Houng Bang Liew, Lieng Hsi Ling, et al. “Multinational and multiethnic variations in health-related quality of life in patients with chronic heart failure.” Am Heart J 191 (September 2017): 75–81. https://doi.org/10.1016/j.ahj.2017.06.016.
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• O’Connor, Christopher M. “America and Apple Pie: How Do We Change the American Health Care System?” Jacc Heart Fail 5, no. 9 (September 2017): 686–87. https://doi.org/10.1016/j.jchf.2017.07.006.
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• Sherwood, Andrew, LaBarron K. Hill, James A. Blumenthal, Kirkwood F. Adams, Nicola J. Paine, Gary G. Koch, Christopher M. O’Connor, Kristy S. Johnson, and Alan L. Hinderliter. “Blood pressure reactivity to psychological stress is associated with clinical outcomes in patients with heart failure.” Am Heart J 191 (September 2017): 82–90. https://doi.org/10.1016/j.ahj.2017.07.003.
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• O’Connor, Christopher M. “Does Institutional Memory Matter?” Jacc Heart Fail 5, no. 8 (August 2017): 616. https://doi.org/10.1016/j.jchf.2017.07.001.
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• Rogers, Joseph G., Chetan B. Patel, Robert J. Mentz, Bradi B. Granger, Karen E. Steinhauser, Mona Fiuzat, Patricia A. Adams, et al. “Palliative Care in Heart Failure: The PAL-HF Randomized, Controlled Clinical Trial.” J Am Coll Cardiol 70, no. 3 (July 18, 2017): 331–41. https://doi.org/10.1016/j.jacc.2017.05.030.
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• O’Connor, Christopher M. “A Decade With Editorial Mentors: The Day They Dropped the Mic.” Jacc Heart Fail 5, no. 7 (July 2017): 541–42. https://doi.org/10.1016/j.jchf.2017.05.009.
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• Tromp, Jasper, Mohsin A. F. Khan, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Biomarker Profiles of Acute Heart Failure Patients With a Mid-Range Ejection Fraction.” Jacc Heart Fail 5, no. 7 (July 2017): 507–17. https://doi.org/10.1016/j.jchf.2017.04.007.
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• Greene, Stephen J., Adrian F. Hernandez, Allison Dunning, Andrew P. Ambrosy, Paul W. Armstrong, Javed Butler, Lukasz P. Cerbin, et al. “Hospitalization for Recently Diagnosed Versus Worsening Chronic Heart Failure: From the ASCEND-HF Trial.” J Am Coll Cardiol 69, no. 25 (June 27, 2017): 3029–39. https://doi.org/10.1016/j.jacc.2017.04.043.
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• O’Connor, Christopher M. “Development of Acute Decompensated Heart Failure Therapies: Is the Journey Over?” Jacc Heart Fail 5, no. 6 (June 2017): 464–65. https://doi.org/10.1016/j.jchf.2017.04.010.
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• Raslan, Ismail R., Paul Brown, Cynthia M. Westerhout, Justin A. Ezekowitz, Adrian F. Hernandez, Randall C. Starling, Christopher O’Connor, et al. “Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score.” Am Heart J 188 (June 2017): 127–35. https://doi.org/10.1016/j.ahj.2017.03.014.
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• Banks, Adam, Samuel Broderick, Karen Chiswell, Linda Shaw, Adam Devore, Mona Fiuzat, Christopher O’Connor, Gary Michael Felker, Eric Velazquez, and Robert Mentz. “Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease).” Am J Cardiol 119, no. 11 (June 1, 2017): 1703–9. https://doi.org/10.1016/j.amjcard.2017.02.053.
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• Cleland, John G. F., John R. Teerlink, Beth A. Davison, Ahmad Shoaib, Marco Metra, Stefanie Senger, Olga Milo, et al. “Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS).” Eur J Heart Fail 19, no. 6 (June 2017): 739–47. https://doi.org/10.1002/ejhf.786.
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• Demissei, Biniyam G., Douwe Postmus, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “Plasma biomarkers to predict or rule out early post-discharge events after hospitalization for acute heart failure.” Eur J Heart Fail 19, no. 6 (June 2017): 728–38. https://doi.org/10.1002/ejhf.766.
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• Packer, Milton, Christopher O’Connor, John J. V. McMurray, Janet Wittes, William T. Abraham, Stefan D. Anker, Kenneth Dickstein, et al. “Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure.” N Engl J Med 376, no. 20 (May 18, 2017): 1956–64. https://doi.org/10.1056/NEJMoa1601895.
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• O’Connor, Christopher M. “High Heart Failure Readmission Rates: Is It the Health System's Fault?” Jacc Heart Fail 5, no. 5 (May 2017): 393. https://doi.org/10.1016/j.jchf.2017.03.011.
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• Packer, Milton, Richard Holcomb, William T. Abraham, Stefan Anker, Kenneth Dickstein, Gerasimos Filippatos, Henry Krum, et al. “Rationale for and design of the TRUE-AHF trial: the effects of ularitide on the short-term clinical course and long-term mortality of patients with acute heart failure.” Eur J Heart Fail 19, no. 5 (May 2017): 673–81. https://doi.org/10.1002/ejhf.698.
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• Reeves, Gordon R., David J. Whellan, Christopher M. O’Connor, Pamela Duncan, Joel D. Eggebeen, Timothy M. Morgan, Leigh Ann Hewston, Amy Pastva, Mahesh J. Patel, and Dalane W. Kitzman. “A Novel Rehabilitation Intervention for Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Pilot Study.” Jacc Heart Fail 5, no. 5 (May 2017): 359–66. https://doi.org/10.1016/j.jchf.2016.12.019.
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• Luo, Nancy, Peter Merrill, Kishan S. Parikh, David J. Whellan, Ileana L. Piña, Mona Fiuzat, William E. Kraus, et al. “Exercise Training in Patients With Chronic Heart Failure and Atrial Fibrillation.” J Am Coll Cardiol 69, no. 13 (April 4, 2017): 1683–91. https://doi.org/10.1016/j.jacc.2017.01.032.
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• Butler, Javed, Carine E. Hamo, James E. Udelson, Christopher O’Connor, Hani N. Sabbah, Marco Metra, Sanjiv J. Shah, et al. “Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations.” Circ Heart Fail 10, no. 4 (April 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003800.
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• O’Connor, Christopher M., and Dirk J. van Veldhuisen. “Data Sharing From the Editors' Perspective: Our Hope With Limitations.” Jacc Heart Fail 5, no. 4 (April 2017): 314–15. https://doi.org/10.1016/j.jchf.2017.02.007.
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• Ambrosy, Andrew P., Lukasz P. Cerbin, Adam D. DeVore, Stephen J. Greene, William E. Kraus, Christopher M. O’Connor, Ileana L. Piña, et al. “Aerobic exercise training and general health status in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)trial.” Am Heart J 186 (April 2017): 130–38. https://doi.org/10.1016/j.ahj.2016.12.017.
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• Sun, Julia L., Stephen H. Boyle, Zainab Samad, Michael A. Babyak, Jennifer L. Wilson, Cynthia Kuhn, Richard C. Becker, et al. “Mental stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients.” Eur J Prev Cardiol 24, no. 6 (April 2017): 591–99. https://doi.org/10.1177/2047487316686435.
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• O’Connor, Christopher M., David J. Whellan, Mona Fiuzat, Naresh M. Punjabi, Gudaye Tasissa, Kevin J. Anstrom, Adam V. Benjafield, et al. “Cardiovascular Outcomes With Minute Ventilation-Targeted Adaptive Servo-Ventilation Therapy in Heart Failure: The CAT-HF Trial.” J Am Coll Cardiol 69, no. 12 (March 28, 2017): 1577–87. https://doi.org/10.1016/j.jacc.2017.01.041.
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• Felker, G Michael, Robert J. Mentz, Robert T. Cole, Kirkwood F. Adams, Gregory F. Egnaczyk, Mona Fiuzat, Chetan B. Patel, et al. “Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure.” J Am Coll Cardiol 69, no. 11 (March 21, 2017): 1399–1406. https://doi.org/10.1016/j.jacc.2016.09.004.
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• Levy, Wayne C., Yanhong Li, Shelby D. Reed, Michael R. Zile, Ramin Shadman, Todd Dardas, David J. Whellan, et al. “Does the Implantable Cardioverter-Defibrillator Benefit Vary With the Estimated Proportional Risk of Sudden Death in Heart Failure Patients?” Jacc Clin Electrophysiol 3, no. 3 (March 2017): 291–98. https://doi.org/10.1016/j.jacep.2016.09.006.
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• Matsue, Yuya, Jozine M. Ter Maaten, Joachim Struck, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure.” J Card Fail 23, no. 3 (March 2017): 231–39. https://doi.org/10.1016/j.cardfail.2016.09.007.
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• Matsue, Yuya, Peter van der Meer, Kevin Damman, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Blood urea nitrogen-to-creatinine ratio in the general population and in patients with acute heart failure.” Heart 103, no. 6 (March 2017): 407–13. https://doi.org/10.1136/heartjnl-2016-310112.
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• O’Connor, Christopher M. “Is Salt Bad for You?” Jacc Heart Fail 5, no. 3 (March 2017): 238–39. https://doi.org/10.1016/j.jchf.2017.01.003.
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• Reeves, Gordon R., David J. Whellan, Pamela Duncan, Christopher M. O’Connor, Amy M. Pastva, Joel D. Eggebeen, Leigh Ann Hewston, et al. “Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale.” Am Heart J 185 (March 2017): 130–39. https://doi.org/10.1016/j.ahj.2016.12.012.
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• Feigal, Jacob P., Stephen H. Boyle, Zainab Samad, Eric J. Velazquez, Jennifer L. Wilson, Richard C. Becker, Redford B. Williams, et al. “Associations between positive emotional well-being and stress-induced myocardial ischemia: Well-being scores predict exercise-induced ischemia.” Journal of Psychosomatic Research 93 (February 2017): 14–18. https://doi.org/10.1016/j.jpsychores.2016.11.012.
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• Kitai, Takeshi, Justin L. Grodin, Robert J. Mentz, Adrian F. Hernandez, Javed Butler, Marco Metra, John J. McMurray, et al. “Insufficient reduction in heart rate during hospitalization despite beta-blocker treatment in acute decompensated heart failure: insights from the ASCEND-HF trial.” Eur J Heart Fail 19, no. 2 (February 2017): 241–49. https://doi.org/10.1002/ejhf.629.
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• O’Connor, Christopher M. “21st Century Cures: A Step Forward for Patients With Heart Failure.” Jacc Heart Fail 5, no. 2 (February 2017): 154. https://doi.org/10.1016/j.jchf.2016.12.004.
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• Tromp, Jasper, Jozine M. Ter Maaten, Kevin Damman, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials).” Am J Cardiol 119, no. 2 (January 15, 2017): 290–96. https://doi.org/10.1016/j.amjcard.2016.09.038.
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• Navarese, Eliano P., Paul A. Gurbel, Felicita Andreotti, Michalina Marta Kołodziejczak, Suetonia C. Palmer, Sofia Dias, Antonino Buffon, et al. “Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis.” Plos One 12, no. 2 (2017): e0168726. https://doi.org/10.1371/journal.pone.0168726.
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• O’Connor, C. “HFSA President's Paper (Accepted).” Journal of Cardiac Failure, January 1, 2017. https://doi.org/10.1016/j.cardfail.2017.07.399.
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• O’Connor, Christopher M. “Developing Breakthrough Drugs for Heart Failure: Lessons Learned From the Cystic Fibrosis Experience.” Jacc Heart Fail 5, no. 1 (January 2017): 71–72. https://doi.org/10.1016/j.jchf.2016.11.008.
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• Ambrosy, Andrew P., Lukasz P. Cerbin, Paul W. Armstrong, Javed Butler, Adrian Coles, Adam D. DeVore, Mark E. Dunlap, et al. “Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From the ASCEND-HF Trial.” Jacc Heart Fail 5, no. 1 (January 2017): 1–13. https://doi.org/10.1016/j.jchf.2016.09.012.
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• Sherwood, Andrew, James A. Blumenthal, Gary G. Koch, Benson M. Hoffman, Lana L. Watkins, Patrick J. Smith, Christopher M. O’Connor, et al. “Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial.” Circ Heart Fail 10, no. 1 (January 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003410.
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• Streng, Koen W., Jozine M. Ter Maaten, John G. Cleland, Christopher M. O’Connor, Beth A. Davison, Marco Metra, Michael M. Givertz, et al. “Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure.” Circulation. Heart Failure 10, no. 1 (January 2017): e003350. https://doi.org/10.1161/circheartfailure.116.003350.
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• Verma, Amanda K., Phillip J. Schulte, Vera Bittner, Steven J. Keteyian, Jerome L. Fleg, Ileana L. Piña, Ann M. Swank, et al. “Socioeconomic and partner status in chronic heart failure: Relationship to exercise capacity, quality of life, and clinical outcomes.” Am Heart J 183 (January 2017): 54–61. https://doi.org/10.1016/j.ahj.2016.10.007.
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• Vegter, Eline L., Daniela Schmitter, Yanick Hagemeijer, Ekaterina S. Ovchinnikova, Pim van der Harst, John R. Teerlink, Christopher M. O’Connor, et al. “Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure.” Int J Cardiol 224 (December 1, 2016): 231–39. https://doi.org/10.1016/j.ijcard.2016.09.010.
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• O’Connor, Christopher M. “Not Your Mother's FDA.” Jacc Heart Fail 4, no. 12 (December 2016): 978. https://doi.org/10.1016/j.jchf.2016.10.001.
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• Demissei, Biniyam G., Douwe Postmus, Licette C. Y. Liu, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, et al. “Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial.” Int J Cardiol 223 (November 15, 2016): 967–75. https://doi.org/10.1016/j.ijcard.2016.08.271.
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• O’Connor, Christopher M. “Peer Review of Peer Review: Somewhere Over the Rainbow.” Jacc Heart Fail 4, no. 11 (November 2016): 907–8. https://doi.org/10.1016/j.jchf.2016.09.005.
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• Parikh, Kishan S., Adrian Coles, Phillip J. Schulte, William E. Kraus, Jerome L. Fleg, Steven J. Keteyian, Ileana L. Piña, et al. “Relation of Angina Pectoris to Outcomes, Quality of Life, and Response to Exercise Training in Patients With Chronic Heart Failure (from HF-ACTION).” Am J Cardiol 118, no. 8 (October 15, 2016): 1211–16. https://doi.org/10.1016/j.amjcard.2016.07.040.
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• Tromp, Jasper, Sven Meyer, Robert J. Mentz, Christopher M. O’Connor, Marco Metra, Howard C. Dittrich, Piotr Ponikowski, et al. “Acute heart failure in the young: Clinical characteristics and biomarker profiles.” Int J Cardiol 221 (October 15, 2016): 1067–72. https://doi.org/10.1016/j.ijcard.2016.06.339.
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• Cotter, Gad, Beth A. Davison, Olga Milo, Robert C. Bourge, John G. F. Cleland, Guillaume Jondeau, Henry Krum, et al. “Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.” J Card Fail 22, no. 10 (October 2016): 815–22. https://doi.org/10.1016/j.cardfail.2015.12.017.
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• O’Connor, Christopher M. “The International Olympic Games: Heart Teams and Heart Failure.” Jacc Heart Fail 4, no. 10 (October 2016): 826–27. https://doi.org/10.1016/j.jchf.2016.08.004.
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• O’Connor, Christopher M. “The Mentor's Mentor: The Life of Galen Wagner.” Jacc Heart Fail 4, no. 9 (September 2016): 759. https://doi.org/10.1016/j.jchf.2016.07.009.
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• Greene, Stephen J., Adrian F. Hernandez, Jie-Lena Sun, Marco Metra, Javed Butler, Andrew P. Ambrosy, Justin A. Ezekowitz, et al. “Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Circ Heart Fail 9, no. 9 (September 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.002986.
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• Luo, Nancy, Joseph G. Rogers, Gwen C. Dodson, Chetan B. Patel, Anthony N. Galanos, Carmelo A. Milano, Christopher M. O’Connor, and Robert J. Mentz. “Usefulness of Palliative Care to Complement the Management of Patients on Left Ventricular Assist Devices.” Am J Cardiol 118, no. 5 (September 1, 2016): 733–38. https://doi.org/10.1016/j.amjcard.2016.06.010.
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• O’Connor, Christopher M. “Can Academic Cardiology Divisions Survive?” Jacc Heart Fail 4, no. 8 (August 2016): 687–88. https://doi.org/10.1016/j.jchf.2016.06.001.
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• Davison, Beth A., Marco Metra, Stefanie Senger, Christopher Edwards, Olga Milo, Daniel M. Bloomfield, John G. Cleland, et al. “Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality.” Eur J Heart Fail 18, no. 8 (August 2016): 1041–50. https://doi.org/10.1002/ejhf.540.
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• Kelly, Jacob P., Allison Dunning, Phillip J. Schulte, Mona Fiuzat, Eric S. Leifer, Jerome L. Fleg, Lawton S. Cooper, et al. “Statins and Exercise Training Response in Heart Failure Patients: Insights From HF-ACTION.” Jacc Heart Fail 4, no. 8 (August 2016): 617–24. https://doi.org/10.1016/j.jchf.2016.05.006.
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• Kelly, Jacob P., Lauren B. Cooper, Dianne Gallup, Kevin J. Anstrom, Horng H. Chen, Margaret M. Redfield, Christopher M. O’Connor, Robert J. Mentz, Adrian F. Hernanadez, and G Michael Felker. “Implications of Using Different Definitions on Outcomes in Worsening Heart Failure.” Circ Heart Fail 9, no. 8 (August 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003048.
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• Paine, Nicola J., Alan L. Hinderliter, James A. Blumenthal, Kirkwood F. Adams, Carla A. Sueta, Patricia P. Chang, Christopher M. O’Connor, and Andrew Sherwood. “Reactive hyperemia is associated with adverse clinical outcomes in heart failure.” Am Heart J 178 (August 2016): 108–14. https://doi.org/10.1016/j.ahj.2016.05.008.
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• Ter Maaten, Jozine M., Kevin Damman, Jennifer S. Hanberg, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, John R. Teerlink, et al. “Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure.” Circ Heart Fail 9, no. 8 (August 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.116.003109.
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• Denardo, Scott J., David M. Vock, Carsten M. Schmalfuss, Gregory D. Young, James E. Tcheng, and Christopher M. O’Connor. “Baseline Hemodynamics and Response to Contrast Media During Diagnostic Cardiac Catheterization Predict Adverse Events in Heart Failure Patients.” Circ Heart Fail 9, no. 7 (July 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002529.
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• O’Connor, Christopher M. “The Year in Heart Failure Review 2015 to 2016.” Jacc Heart Fail 4, no. 7 (July 2016): 603–4. https://doi.org/10.1016/j.jchf.2016.05.005.
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• Banks, Adam Z., Robert J. Mentz, Amanda Stebbins, Catherine R. Mikus, Phillip J. Schulte, Jerome L. Fleg, Lawton S. Cooper, et al. “Response to Exercise Training and Outcomes in Patients With Heart Failure and Diabetes Mellitus: Insights From the HF-ACTION Trial.” J Card Fail 22, no. 7 (July 2016): 485–91. https://doi.org/10.1016/j.cardfail.2015.12.007.
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• Biegus, Jan, Hans L. Hillege, Douwe Postmus, Mattia A. E. Valente, Daniel M. Bloomfield, John G. F. Cleland, Gad Cotter, et al. “Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study.” Eur J Heart Fail 18, no. 7 (July 2016): 830–39. https://doi.org/10.1002/ejhf.532.
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• Reeves, Gordon R., David J. Whellan, Mahesh J. Patel, Christopher M. O’Connor, Pamela Duncan, Joel D. Eggebeen, Timothy M. Morgan, Leigh A. Hewston, Amy M. Pastva, and Dalane W. Kitzman. “Comparison of Frequency of Frailty and Severely Impaired Physical Function in Patients ≥60 Years Hospitalized With Acute Decompensated Heart Failure Versus Chronic Stable Heart Failure With Reduced and Preserved Left Ventricular Ejection Fraction.” Am J Cardiol 117, no. 12 (June 15, 2016): 1953–58. https://doi.org/10.1016/j.amjcard.2016.03.046.
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• Emmens, Johanna E., Jozine M. Ter Maaten, Yuya Matsue, Marco Metra, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome.” Eur J Heart Fail 18, no. 6 (June 2016): 641–49. https://doi.org/10.1002/ejhf.426.
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• Metra, Marco, Robert J. Mentz, Adrian F. Hernandez, Gretchen M. Heizer, Paul W. Armstrong, Nadine Clausell, Ramon Corbalan, et al. “Geographic Differences in Patients in a Global Acute Heart Failure Clinical Trial (from the ASCEND-HF Trial).” Am J Cardiol 117, no. 11 (June 1, 2016): 1771–78. https://doi.org/10.1016/j.amjcard.2016.03.002.
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• O’Connor, Christopher M. “Social Media: Can It Reduce Heart Failure Events?” Jacc Heart Fail 4, no. 6 (June 2016): 514–15. https://doi.org/10.1016/j.jchf.2016.04.006.
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• Ter Maaten, Jozine M., Mattia A. E. Valente, Kevin Damman, John G. Cleland, Michael M. Givertz, Marco Metra, Christopher M. O’Connor, et al. “Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure.” Circ Heart Fail 9, no. 6 (June 2016). https://doi.org/10.1161/CIRCHEARTFAILURE.115.002845.
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• Whellan, David J., Amanda Stebbins, Adrian F. Hernandez, Justin A. Ezekowitz, John J. V. McMurray, Paul J. Mather, Vic Hasselblad, and Christopher M. O’Connor. “Dichotomous Relationship Between Age and 30-Day Death or Rehospitalization in Heart Failure Patients Admitted With Acute Decompensated Heart Failure: Results From the ASCEND-HF Trial.” J Card Fail 22, no. 6 (June 2016): 409–16. https://doi.org/10.1016/j.cardfail.2016.02.011.
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• Wong, Yee Weng, Robert J. Mentz, G Michael Felker, Justin Ezekowitz, Karen Pieper, Gretchen Heizer, Vic Hasselblad, et al. “Nesiritide in patients hospitalized for acute heart failure: does timing matter? Implication for future acute heart failure trials.” Eur J Heart Fail 18, no. 6 (June 2016): 684–92. https://doi.org/10.1002/ejhf.487.
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• Navarese, Eliano P., Michalina Kolodziejczak, Dean J. Kereiakes, Udaya S. Tantry, Christopher O’Connor, and Paul A. Gurbel. “Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review.” Ann Intern Med 164, no. 9 (May 3, 2016): 600–607. https://doi.org/10.7326/M15-2994.
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• O’Connor, Christopher M., Mona Fiuzat, and JoAnn Lindenfeld. “Are We Really in Love With Old Therapies?” Jacc Heart Fail, April 12, 2016. https://doi.org/10.1016/j.jchf.2016.02.011.
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• Garber, Adam M., Robert J. Mentz, Hussein R. Al-Khalidi, Linda K. Shaw, Mona Fiuzat, Christopher M. O’Connor, and Eric J. Velazquez. “Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction.” J Thromb Thrombolysis 41, no. 3 (April 2016): 365–73. https://doi.org/10.1007/s11239-015-1252-0.
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• O’Connor, Christopher M. “I Lost a Friend From HFpEF: William Anlyan, MD, Chancellor Emeritus and Duke University Trustee.” Jacc Heart Fail 4, no. 3 (March 2016): 230–31. https://doi.org/10.1016/j.jchf.2016.01.007.
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• Cooper, Lauren B., Robert J. Mentz, Susanna R. Stevens, G Michael Felker, Carlo Lombardi, Marco Metra, Lynne W. Stevenson, et al. “Hemodynamic Predictors of Heart Failure Morbidity and Mortality: Fluid or Flow?” J Card Fail 22, no. 3 (March 2016): 182–89. https://doi.org/10.1016/j.cardfail.2015.11.012.
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• Demissei, Biniyam G., Mattia A. E. Valente, John G. Cleland, Christopher M. O’Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, et al. “Optimizing clinical use of biomarkers in high-risk acute heart failure patients.” Eur J Heart Fail 18, no. 3 (March 2016): 269–80. https://doi.org/10.1002/ejhf.443.
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• Perez, Antonio L., Justin L. Grodin, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, G Michael Felker, et al. “Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy.” Eur J Heart Fail 18, no. 3 (March 2016): 290–97. https://doi.org/10.1002/ejhf.456.
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• Keteyian, Steven J., Mahesh Patel, William E. Kraus, Clinton A. Brawner, Timothy R. McConnell, Ileana L. Piña, Eric S. Leifer, et al. “Variables Measured During Cardiopulmonary Exercise Testing as Predictors of Mortality in Chronic Systolic Heart Failure.” J Am Coll Cardiol 67, no. 7 (February 23, 2016): 780–89. https://doi.org/10.1016/j.jacc.2015.11.050.
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• Fiuzat, Mona, Daniel Wojdyla, Ileana Pina, Kirkwood Adams, David Whellan, and Christopher M. O’Connor. “Heart Rate or Beta-Blocker Dose? Association With Outcomes in Ambulatory Heart Failure Patients With Systolic Dysfunction: Results From the HF-ACTION Trial.” Jacc Heart Fail 4, no. 2 (February 2016): 109–15. https://doi.org/10.1016/j.jchf.2015.09.002.
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• Maaten, Jozine M. ter, Mattia A. E. Valente, Marco Metra, Noemi Bruno, Christopher M. O’Connor, Piotr Ponikowski, John R. Teerlink, et al. “A combined clinical and biomarker approach to predict diuretic response in acute heart failure.” Clin Res Cardiol 105, no. 2 (February 2016): 145–53. https://doi.org/10.1007/s00392-015-0896-2.
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• Mark, Daniel B., and Christopher M. O’Connor. “When Business and Science Clash, How Can We Avoid Harming Patients?: The Case of AVOID-HF.” Jacc Heart Fail 4, no. 2 (February 2016): 106–8. https://doi.org/10.1016/j.jchf.2015.09.001.
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• Mentz, Robert J., Vic Hasselblad, Adam D. DeVore, Marco Metra, Adriaan A. Voors, Paul W. Armstrong, Justin A. Ezekowitz, et al. “Torsemide Versus Furosemide in Patients With Acute Heart Failure (from the ASCEND-HF Trial).” Am J Cardiol 117, no. 3 (February 1, 2016): 404–11. https://doi.org/10.1016/j.amjcard.2015.10.059.
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• O’Connor, Christopher M. “Death of the Heart Failure Clinical Investigator: Molecules and Receptors Win Nobel Prizes, Clinical Investigation Improves Survival.” Jacc Heart Fail 4, no. 2 (February 2016): 162–63. https://doi.org/10.1016/j.jchf.2015.12.001.
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• Ahmad, Tariq, Jacob P. Kelly, Robert W. McGarrah, Anne S. Hellkamp, Mona Fiuzat, Jeffrey M. Testani, Teresa S. Wang, et al. “Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support.” J Am Coll Cardiol 67, no. 3 (January 26, 2016): 291–99. https://doi.org/10.1016/j.jacc.2015.10.079.
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• Bruno, Noemi, Jozine M. ter Maaten, Ekaterina S. Ovchinnikova, Eline L. Vegter, Mattia A. E. Valente, Peter van der Meer, Rudolf A. de Boer, et al. “MicroRNAs relate to early worsening of renal function in patients with acute heart failure.” Int J Cardiol 203 (January 15, 2016): 564–69. https://doi.org/10.1016/j.ijcard.2015.10.217.
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• O’Connor, Christopher M. “Why Dr. Robert Califf's Nomination for Commissioner of the Food and Drug Administration Is Good for Heart Failure Patients.” Jacc Heart Fail 4, no. 1 (January 2016): 90–91. https://doi.org/10.1016/j.jchf.2015.11.004.
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• Ahmad, Tariq, Nihar Desai, Francis Wilson, Phillip Schulte, Allison Dunning, Daniel Jacoby, Larry Allen, et al. “Clinical Implications of Cluster Analysis-Based Classification of Acute Decompensated Heart Failure and Correlation with Bedside Hemodynamic Profiles.” Plos One 11, no. 2 (2016): e0145881. https://doi.org/10.1371/journal.pone.0145881.
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• Mentz, Robert J., and Christopher M. O’Connor. “Pathophysiology and clinical evaluation of acute heart failure.” Nat Rev Cardiol 13, no. 1 (January 2016): 28–35. https://doi.org/10.1038/nrcardio.2015.134.
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• Tang, WH Wilson, Yuping Wu, Justin L. Grodin, Amy P. Hsu, Adrian F. Hernandez, Javed Butler, Marco Metra, et al. “Prognostic Value of Baseline and Changes in Circulating Soluble ST2 Levels and the Effects of Nesiritide in Acute Decompensated Heart Failure.” Jacc Heart Fail 4, no. 1 (January 2016): 68–77. https://doi.org/10.1016/j.jchf.2015.07.015.
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• Brunner-La Rocca, Hans-Peter, Luc Eurlings, A Mark Richards, James L. Januzzi, Matthias E. Pfisterer, Ulf Dahlström, Yigal M. Pinto, et al. “Which heart failure patients profit from natriuretic peptide guided therapy? A meta-analysis from individual patient data of randomized trials.” Eur J Heart Fail 17, no. 12 (December 2015): 1252–61. https://doi.org/10.1002/ejhf.401.
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• O’Connor, Christopher M. “Heart Failure "End Result Cards": Solid B.” Jacc Heart Fail 3, no. 12 (December 2015): 1001–2. https://doi.org/10.1016/j.jchf.2015.10.004.
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• Cooper, Lauren B., Robert J. Mentz, Jie-Lena Sun, Phillip J. Schulte, Jerome L. Fleg, Lawton S. Cooper, Ileana L. Piña, et al. “Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION).” Circ Heart Fail 8, no. 6 (November 2015): 1044–51. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002327.
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• O’Connor, Christopher M. “Bundle Up for Value-Based Heart Failure Care.” Jacc Heart Fail 3, no. 11 (November 2015): 931–32. https://doi.org/10.1016/j.jchf.2015.09.003.
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• Samad, Zainab, Linda K. Shaw, Matthew Phelan, Mads Ersboll, Niels Risum, Hussein R. Al-Khalidi, Donald D. Glower, et al. “Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction.” Eur Heart J 36, no. 40 (October 21, 2015): 2733–41. https://doi.org/10.1093/eurheartj/ehv343.
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• Grodin, Justin L., Antonio L. Perez, Yuping Wu, Adrian F. Hernandez, Javed Butler, Marco Metra, G Michael Felker, et al. “Circulating Kidney Injury Molecule-1 Levels in Acute Heart Failure: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).” Jacc Heart Fail 3, no. 10 (October 2015): 777–85. https://doi.org/10.1016/j.jchf.2015.06.006.
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• O’Connor, Christopher M. “Physician-Leaders: A Call for Cardiovascular Specialists to Step Up.” Jacc Heart Fail 3, no. 10 (October 2015): 843–44. https://doi.org/10.1016/j.jchf.2015.08.004.
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• Felker, G Michael, Robert J. Mentz, Kirkwood F. Adams, Robert T. Cole, Gregory F. Egnaczyk, Chetan B. Patel, Mona Fiuzat, et al. “Tolvaptan in Patients Hospitalized With Acute Heart Failure: Rationale and Design of the TACTICS and the SECRET of CHF Trials.” Circ Heart Fail 8, no. 5 (September 2015): 997–1005. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002259.
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• Mentz, Robert J., Eric J. Velazquez, Marco Metra, Colleen McKendry, Karen Chiswell, Mona Fiuzat, Michael M. Givertz, Adriaan A. Voors, John R. Teerlink, and Christopher M. O’Connor. “Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial.” Future Cardiol 11, no. 5 (September 2015): 585–95. https://doi.org/10.2217/fca.15.56.
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• O’Connor, Christopher M. “What Is a Life Worth?: A Tribute to Dr. William Little, a Pioneer in the Understanding of Heart Failure With Preserved Ejection Fraction.” Jacc Heart Fail 3, no. 9 (September 2015): 734–35. https://doi.org/10.1016/j.jchf.2015.07.002.
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• Xiong, Glen L., Kevin Prybol, Stephen H. Boyle, Russell Hall, Robert D. Streilein, David C. Steffens, Ranga Krishnan, et al. “Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study.” Psychosom Med 77, no. 7 (September 2015): 808–15. https://doi.org/10.1097/PSY.0000000000000216.
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• Abualnaja, Seraj, Mohua Podder, Adrian F. Hernandez, John J. V. McMurray, Randall C. Starling, Christopher M. O’Connor, Robert M. Califf, Paul W. Armstrong, and Justin A. Ezekowitz. “Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) Trial.” J Am Heart Assoc 4, no. 8 (August 24, 2015): e002092. https://doi.org/10.1161/JAHA.115.002092.
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• O’Connor, Christopher M., and Tariq Ahmad. “The Role of Sodium and Chloride in Heart Failure: Does It Take Two to Tango?” J Am Coll Cardiol 66, no. 6 (August 11, 2015): 667–69. https://doi.org/10.1016/j.jacc.2015.05.070.
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• Farzaneh-Far, Afshin, Linda K. Shaw, Allison Dunning, Jorge D. Oldan, Christopher M. O’Connor, and Salvador Borges-Neto. “Comparison of the prognostic value of regadenoson and adenosine myocardial perfusion imaging.” J Nucl Cardiol 22, no. 4 (August 2015): 600–607. https://doi.org/10.1007/s12350-015-0155-y.
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• Hess, Paul L., Linda K. Shaw, Sreekanth Vemulapalli, Robert Pagnanelli, Christopher M. O’Connor, and Salvador Borges-Neto. “An alternative method to examine the predictive value of mechanical dyssynchrony.” J Nucl Cardiol 22, no. 4 (August 2015): 686–89. https://doi.org/10.1007/s12350-015-0145-0.
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• O’Connor, Christopher M. “The Globalization of Heart Failure Research.” Jacc Heart Fail 3, no. 8 (August 2015): 657–58. https://doi.org/10.1016/j.jchf.2015.06.001.
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• Dardas, Todd, Yanhong Li, Shelby D. Reed, Christopher M. O’Connor, David J. Whellan, Stephen J. Ellis, Kevin A. Schulman, William E. Kraus, Daniel E. Forman, and Wayne C. Levy. “Incremental and independent value of cardiopulmonary exercise test measures and the Seattle Heart Failure Model for prediction of risk in patients with heart failure.” J Heart Lung Transplant 34, no. 8 (August 2015): 1017–23. https://doi.org/10.1016/j.healun.2015.03.017.
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• Kelly, Jacob P., Robert J. Mentz, Vic Hasselblad, Justin A. Ezekowitz, Paul W. Armstrong, Faiez Zannad, G Michael Felker, Robert M. Califf, Christopher M. O’Connor, and Adrian F. Hernandez. “Worsening heart failure during hospitalization for acute heart failure: Insights from the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF).” Am Heart J 170, no. 2 (August 2015): 298–305. https://doi.org/10.1016/j.ahj.2015.04.007.
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• Khazanie, Prateeti, Gretchen M. Heizer, Vic Hasselblad, Paul W. Armstrong, Robert M. Califf, Justin Ezekowitz, Kenneth Dickstein, et al. “Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models.” Am Heart J 170, no. 2 (August 2015): 290–97. https://doi.org/10.1016/j.ahj.2015.04.006.
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• O’Connor, Christopher M. “RESPONSE: Are We Committed to Training Fellows in Clinical Investigation?” J Am Coll Cardiol 66, no. 3 (July 21, 2015): 326–27.
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• Harinstein, Matthew E., Javed Butler, Stephen J. Greene, Gregg C. Fonarow, Norman L. Stockbridge, Christopher M. O’Connor, Marc A. Pfeffer, et al. “Site selection for heart failure clinical trials in the USA.” Heart Fail Rev 20, no. 4 (July 2015): 375–83. https://doi.org/10.1007/s10741-015-9473-z.
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• Mentz, Robert J., Marco Metra, Gad Cotter, Olga Milo, Colleen McKendry, Karen Chiswell, Beth A. Davison, et al. “Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial.” Eur J Heart Fail 17, no. 7 (July 2015): 697–706. https://doi.org/10.1002/ejhf.308.
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• Taylor, R. S., M. F. Piepoli, N. Smart, A. J. S. Coats, S. Ellis, H. Dalal, C. M. O’Connor, F. C. Warren, D. Whellan, and O. Ciani. “Erratum: Corrigendum to exercise training for chronic heart failure (ExTraMATCH II): Protocol for an individual participant data meta-analysis (Int J Cardiol. (2014) 174:3 (683-687) DOI: http://dx.doi.org/10.1016/j.ijcard.2014.04.203).” International Journal of Cardiology 193 (June 11, 2015): 93. https://doi.org/10.1016/j.ijcard.2014.11.220.
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• Givertz, Michael M., Kevin J. Anstrom, Margaret M. Redfield, Anita Deswal, Haissam Haddad, Javed Butler, WH Wilson Tang, et al. “Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study.” Circulation 131, no. 20 (May 19, 2015): 1763–71. https://doi.org/10.1161/CIRCULATIONAHA.114.014536.
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• O’Connor, Christopher M. “Medical editors' grand rounds: a discussion of timely topics and editorial emergencies.” Jacc Heart Fail 3, no. 5 (May 2015): 422–23. https://doi.org/10.1016/j.jchf.2015.02.001.
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• O’Connor, Christopher M. “Reading RVUs: How can we meet the informational needs of cardiologists?” Jacc Heart Fail 3, no. 4 (April 2015): 340–41. https://doi.org/10.1016/j.jchf.2015.01.001.
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• Jones, W Schuyler, Robert Clare, Stephen J. Ellis, James S. Mills, David L. Fischman, William E. Kraus, David J. Whellan, Christopher M. O’Connor, and Manesh R. Patel. “Effect of peripheral arterial disease on functional and clinical outcomes in patients with heart failure (from HF-ACTION).” Am J Cardiol 108, no. 3 (August 1, 2011): 380–84. https://doi.org/10.1016/j.amjcard.2011.03.057.
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• Shah, Monica R., Robert M. Califf, Anju Nohria, Manju Bhapkar, Margaret Bowers, Donna M. Mancini, Mona Fiuzat, Lynne W. Stevenson, and Christopher M. O’Connor. “The STARBRITE trial: a randomized, pilot study of B-type natriuretic peptide-guided therapy in patients with advanced heart failure.” J Card Fail 17, no. 8 (August 2011): 613–21. https://doi.org/10.1016/j.cardfail.2011.04.012.
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• Rouleau, Jean L., Robert E. Michler, Eric J. Velazquez, Jae K. Oh, Christopher M. O’Connor, Patrice Desvigne-Nickens, George Sopko, Kerry L. Lee, and Robert H. Jones. “The STICH trial: evidence-based conclusions.” Eur J Heart Fail 12, no. 10 (October 2010): 1028–30. https://doi.org/10.1093/eurjhf/hfq140.
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• O’Connor, Christopher M., Michael W. Dunne, Marc A. Pfeffer, Joseph B. Muhlestein, Louis Yao, Sandeep Gupta, Rebecca J. Benner, Marian R. Fisher, Thomas D. Cook, and Thomas D. Investigators in the WIZARD Study. “Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial.” Jama 290, no. 11 (September 17, 2003): 1459–66. https://doi.org/10.1001/jama.290.11.1459.
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• Trichon, Benjamin H., Donald D. Glower, Linda K. Shaw, Christopher H. Cabell, Kevin J. Anstrom, G Michael Felker, and Christopher M. O’Connor. “Survival after coronary revascularization, with and without mitral valve surgery, in patients with ischemic mitral regurgitation.” Circulation 108 Suppl 1 (September 9, 2003): II103–10. https://doi.org/10.1161/01.cir.0000087656.10829.df.
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• Felker, G Michael, Wendy A. Gattis, Jeffrey D. Leimberger, Kirkwood F. Adams, Michael S. Cuffe, Mihai Gheorghiade, and Christopher M. O’Connor. “Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure.” Am J Cardiol 92, no. 5 (September 1, 2003): 625–28. https://doi.org/10.1016/s0002-9149(03)00740-9.
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• Serebruany, Victor L., Alexander H. Glassman, Alex I. Malinin, David C. Sane, Mitchell S. Finkel, Ranga R. Krishnan, Dan Atar, Vladimir Lekht, and Christopher M. O’Connor. “Enhanced platelet/endothelial activation in depressed patients with acute coronary syndromes: evidence from recent clinical trials.” Blood Coagul Fibrinolysis 14, no. 6 (September 2003): 563–67. https://doi.org/10.1097/00001721-200309000-00008.
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• Serebruany, Victor L., Alexander H. Glassman, Alex I. Malinin, Charles B. Nemeroff, Dominique L. Musselman, Louis T. van Zyl, Mitchell S. Finkel, et al. “Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy.” Circulation 108, no. 8 (August 26, 2003): 939–44. https://doi.org/10.1161/01.CIR.0000085163.21752.0A.
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• Hernandez, Adrian F., and Christopher M. O’Connor. “Sparing a little may save a lot: lessons from the Studies of Left Ventricular Dysfunction (SOLVD).” J Am Coll Cardiol 42, no. 4 (August 20, 2003): 709–11. https://doi.org/10.1016/s0735-1097(03)00766-6.
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• Joynt, Karen E., David J. Whellan, and Christopher M. O’Connor. “Depression and cardiovascular disease: mechanisms of interaction.” Biol Psychiatry 54, no. 3 (August 1, 2003): 248–61. https://doi.org/10.1016/s0006-3223(03)00568-7.
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• Serebruany, V. L., A. H. Glassman, A. I. Malinin, D. Atar, D. C. Sane, B. R. Oshrine, J. J. Ferguson, and C. M. O’Connor. “Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin.” Eur J Heart Fail 5, no. 4 (August 2003): 517–21. https://doi.org/10.1016/s1388-9842(03)00005-9.
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• Jiang, Wei, Michael A. Babyak, Alan Rozanski, Andrew Sherwood, Christopher M. O’Connor, Robert A. Waugh, R Edward Coleman, Michael W. Hanson, James J. Morris, and James A. Blumenthal. “Depression and increased myocardial ischemic activity in patients with ischemic heart disease.” Am Heart J 146, no. 1 (July 2003): 55–61. https://doi.org/10.1016/S0002-8703(03)00152-2.
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• Lee, Craig R., Michael L. Watkins, J Herbert Patterson, Wendy Gattis, Christopher M. O’connor, Mihai Gheorghiade, and Kirkwood F. Adams. “Vasopressin: a new target for the treatment of heart failure.” Am Heart J 146, no. 1 (July 2003): 9–18. https://doi.org/10.1016/S0002-8703(02)94708-3.
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• Serebruany, Victor L., Alex I. Malinin, Christopher M. O’connor, Paul A. Gurbel, and Paul A. Roxifiban Oral Compound Kinetics Evaluation Trial-I Platelet Substudy. “Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy).” Am Heart J 146, no. 1 (July 2003): 91–98. https://doi.org/10.1016/S0002-8703(03)00186-8.
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• Gurbel, Paul A., Kevin P. Bliden, Bonnie L. Hiatt, and Christopher M. O’Connor. “Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.” Circulation 107, no. 23 (June 17, 2003): 2908–13. https://doi.org/10.1161/01.CIR.0000072771.11429.83.
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• Klein, Liviu, Christopher M. O’Connor, Wendy A. Gattis, Manuela Zampino, Leonardo de Luca, Antonio Vitarelli, Francesco Fedele, and Mihai Gheorghiade. “Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations.” Am J Cardiol 91, no. 9A (May 8, 2003): 18F-40F. https://doi.org/10.1016/s0002-9149(02)03336-2.
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• O’Connor, Christopher M., Wendy A. Gattis, Kirkwood F. Adams, Vic Hasselblad, Bleakley Chandler, Aline Frey, Isaac Kobrin, et al. “Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4).” J Am Coll Cardiol 41, no. 9 (May 7, 2003): 1452–57. https://doi.org/10.1016/s0735-1097(03)00194-3.
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• Bourque, Jamieson MacDonald, Eric J. Velazquez, Salvador Borges-Neto, Linda K. Shaw, David J. Whellan, and Christopher M. O’Connor. “Radionuclide viability testing: should it affect treatment strategy in patients with cardiomyopathy and significant coronary artery disease?” Am Heart J 145, no. 5 (May 2003): 758–67. https://doi.org/10.1016/S0002-8703(02)94818-0.
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• Felker, G Michael, Raymond L. Benza, A Bleakley Chandler, Jeffrey D. Leimberger, Michael S. Cuffe, Robert M. Califf, Mihai Gheorghiade, Christopher M. O’Connor, and Christopher M. OPTIME-CHF Investigators. “Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study.” J Am Coll Cardiol 41, no. 6 (March 19, 2003): 997–1003. https://doi.org/10.1016/s0735-1097(02)02968-6.
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• Malinin, Alex I., Christopher M. O’Connor, Alec I. Dzhanashvili, David C. Sane, and Victor L. Serebruany. “Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel?” Am Heart J 145, no. 3 (March 2003): 397–403. https://doi.org/10.1067/mhj.2003.163.
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• Trichon, Benjamin H., G Michael Felker, Linda K. Shaw, Christopher H. Cabell, and Christopher M. O’Connor. “Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure.” Am J Cardiol 91, no. 5 (March 1, 2003): 538–43. https://doi.org/10.1016/s0002-9149(02)03301-5.
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• Felker, G Michael, Kirkwood F. Adams, Marvin A. Konstam, Christopher M. O’Connor, and Mihai Gheorghiade. “The problem of decompensated heart failure: nomenclature, classification, and risk stratification.” Am Heart J 145, no. 2 Suppl (February 2003): S18–25. https://doi.org/10.1067/mhj.2003.150.
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• Felker, G Michael, and Christopher M. O’connor. “A bridge for the 21st century in heart transplantation?” Am Heart J 145, no. 2 (February 2003): 198–99. https://doi.org/10.1067/mhj.2003.51.
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• Gheorghiade, M., W. A. Gattis, C. M. O’Connor, and K. F. Adams. “The management of decompensated heart failure resulting in hospitalization: Proceedings from an expert meeting to review current concepts and to define future directions - Introduction.” American Heart Journal 145, no. 2 SUPPL. (February 1, 2003). https://doi.org/10.1067/mhj.2003.148.
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• Gheorghiade, Mihai, Kirkwood F. Adams, Wendy A. Gattis, John R. Teerlink, Cesare Orlandi, and Christopher M. O’Connor. “Surrogate end points in heart failure trials.” Am Heart J 145, no. 2 Suppl (February 2003): S67–70. https://doi.org/10.1067/mhj.2003.159.
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• Gheorghiade, Mihai, Wendy A. Gattis, Alejandro Barbagelata, Kirkwood F. Adams, Uri Elkayam, Cesare Orlandi, Christopher M. O’Connor, and Christopher M. Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Congestive Heart Failure Investigators. “Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure.” Am Heart J 145, no. 2 Suppl (February 2003): S51–54. https://doi.org/10.1067/mhj.2003.154.
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• Gheorghiade, Mihai, Wendy A. Gattis, Kirkwood F. Adams, Alan S. Jaffe, Christopher M. O’Connor, Christopher M. Pilot Randomized Study of Nesiritide versus Dobutamine in Heart Failure, and Christopher M. Duke University Cooperative Cardiovascular Studies Investigators. “Rationale and design of the pilot randomized study of nesiritide versus dobutamine in heart failure (PRESERVD-HF).” Am Heart J 145, no. 2 Suppl (February 2003): S55–57. https://doi.org/10.1067/mhj.2003.155.
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• Gheorghiade, Mihai, Wendy A. Gattis, Mary Ann Lukas, Christopher M. O’Connor, and Christopher M. Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure Investigators. “Rationale and design of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) study.” Am Heart J 145, no. 2 Suppl (February 2003): S60–61. https://doi.org/10.1067/mhj.2003.157.
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• O’Connor, Christopher M., Wendy A. Gattis, John R. Teerlink, Kirkwood F. Adams, and Mihai Gheorghiade. “Design considerations and proposed template for clinical trials in hospitalized patients with decompensated chronic heart failure.” Am Heart J 145, no. 2 Suppl (February 2003): S47–50. https://doi.org/10.1067/mhj.2003.153.
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• O’Connor, Christopher M., Wendy A. Gattis, Kirkwood F. Adams, Monica R. Shah, Aline Frey, Mihai Gheorghiade, and Mihai Randomized Intravenous Tezosentan Study Investigators. “Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the fourth Randomized Intravenous Tezosentan Study (RITZ-4).” Am Heart J 145, no. 2 Suppl (February 2003): S58–59. https://doi.org/10.1067/mhj.2003.156.
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• Zampino, Manuela, Christopher M. O’Connor, Wendy A. Gattis, Kirkwood F. Adams, and Mihai Gheorghiade. “Concomitant use of a positive inotropic agent to create a bridge to the successful initiation of beta-blocker therapy in patients with heart failure: a proposal for a trial.” Am Heart J 145, no. 2 Suppl (February 2003): S62–66. https://doi.org/10.1067/mhj.2003.158.
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• Gattis, Wendy A., Christopher M. O’Connor, Jeffrey D. Leimberger, G Michael Felker, Kirkwood F. Adams, and Mihai Gheorghiade. “Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure.” Am J Cardiol 91, no. 2 (January 15, 2003): 169–74. https://doi.org/10.1016/s0002-9149(02)03104-1.
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• Hasdai, David, Eric J. Topol, Rakhi Kilaru, Alexander Battler, Robert A. Harrington, Alec Vahanian, E Magnus Ohman, et al. “Frequency, patient characteristics, and outcomes of mild-to-moderate heart failure complicating ST-segment elevation acute myocardial infarction: lessons from 4 international fibrinolytic therapy trials.” Am Heart J 145, no. 1 (January 2003): 73–79. https://doi.org/10.1067/mhj.2003.53.
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• Bourque, J. M. D., E. J. Velazquez, S. Borges-Neto, V. Hasselblad, and C. M. O’Connor. “A reappraisal of myocardial viability testing in patients with coronary artery disease and left ventricular dysfunction: Can meta-analysis be trusted?” Heartdrug 2, no. 4 (December 1, 2002): 204–5. https://doi.org/10.1159/000065943.
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• Gheorghiade, M., W. A. Gattis, M. A. Lukas, and C. M. O’Connor. “Rationale and design of the initiation management predischarge: Process for assessment of carvedilol therapy for heart failure (IMPACT-HF) study.” Heartdrug 2, no. 4 (December 1, 2002): 164–66. https://doi.org/10.1159/000065939.
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• O’Connor, Christopher M., Wendy A. Gattis, Kirkwood F. Adams, Monica R. Shah, Isaac Kobrin, Aline Frey, and Mihai Gheorghiade. “Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the Randomized Intravenous Tezosentan study (RITZ-4).” Am Heart J 144, no. 4 (October 2002): 583–88. https://doi.org/10.1016/s0002-8703(02)00127-8.
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• Carney, R. M., J. A. Blumenthal, P. K. Stein, L. Watkins, D. Catellier, L. F. Berkman, S. M. Czajkowski, C. O’Connor, P. H. Stone, and K. E. Freedland. “Depression, heart rate variability, and acute myocardial infarction.” Revista De Psiquiatria Clinica 29, no. 3 (September 14, 2002): 158–59.
• Trichon, Benjamin H., and Christopher M. O’Connor. “Secondary mitral and tricuspid regurgitation accompanying left ventricular systolic dysfunction: is it important, and how is it treated?” Am Heart J 144, no. 3 (September 2002): 373–76. https://doi.org/10.1067/mhj.2002.123576.
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• Gurbel, Paul A., Alex I. Malinin, Kevin P. Callahan, Victor L. Serebruany, and Christopher M. O’Connor. “Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation.” Am J Cardiol 90, no. 3 (August 1, 2002): 312–15. https://doi.org/10.1016/s0002-9149(02)02471-2.
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• Serebruany, V., M. McKenzie, A. Meister, S. Fuzaylov, P. Gurbel, D. Atar, W. Gattis, and C. O’Connor. “Whole blood impedance aggregometry for the assessment of platelet function in patients with congestive heart failure (EPCOT Trial).” Eur J Heart Fail 4, no. 4 (August 2002): 461–67. https://doi.org/10.1016/s1388-9842(02)00026-0.
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• O’Connor, Christopher M., Eric J. Velazquez, Laura H. Gardner, Peter K. Smith, Mark F. Newman, Kevin P. Landolfo, Kerry L. Lee, Robert M. Califf, and Robert H. Jones. “Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank).” Am J Cardiol 90, no. 2 (July 15, 2002): 101–7. https://doi.org/10.1016/s0002-9149(02)02429-3.
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• Whellan, David J., and Christopher M. O’Connor. “The state of exercise training: a need for action.” Am Heart J 144, no. 1 (July 2002): 1–4. https://doi.org/10.1067/mhj.2002.123311.
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• Gurbel, Paul A., Wendy A. Gattis, Sergey F. Fuzaylov, Laura Gaulden, Vic Hasselblad, Victor L. Serebruany, and Christopher M. O’Connor. “Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?” Am Heart J 143, no. 6 (June 2002): 1068–75. https://doi.org/10.1067/mhj.2002.121261.
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• Shah, Monica R., Vic Hasselblad, Sandra S. Stinnett, Judith M. Kramer, Steven Grossman, Mihai Gheorghiade, Kirkwood F. Adams, Karl Swedberg, Robert M. Califf, and Christopher M. O’Connor. “Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure.” Eur J Heart Fail 4, no. 3 (June 2002): 297–304. https://doi.org/10.1016/s1388-9842(01)00202-1.
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• Cuffe, Michael S., Robert M. Califf, Kirkwood F. Adams, Raymond Benza, Robert Bourge, Wilson S. Colucci, Barry M. Massie, et al. “Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial.” Jama 287, no. 12 (March 27, 2002): 1541–47. https://doi.org/10.1001/jama.287.12.1541.
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• Jiang, Wei, Vic Hasselblad, Ranga R. Krishnan, and Christopher M. O’Connor. “Patients with CHF and depression have greater risk of mortality and morbidity than patients without depression.” J Am Coll Cardiol 39, no. 5 (March 6, 2002): 919–21. https://doi.org/10.1016/s0735-1097(02)01694-7.
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• O’Connor, C. M., W. A. Gattis, A. S. Hellkamp, A. Langer, R. L. Larsen, R. A. Harrington, S. D. Berkowitz, et al. “Comparison of two aspirin doses on ischemic stroke in post-myocardial infarction patients in the warfarin (Coumadin) Aspirin Reinfarction Study (CARS).” Am J Cardiol 88, no. 5 (September 1, 2001): 541–46. https://doi.org/10.1016/s0002-9149(01)01735-0.
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• Jiang, W., J. Alexander, E. Christopher, M. Kuchibhatla, L. H. Gaulden, M. S. Cuffe, M. A. Blazing, et al. “Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure.” Arch Intern Med 161, no. 15 (August 13, 2001): 1849–56. https://doi.org/10.1001/archinte.161.15.1849.
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• ENRICHD Investigators, J. I. “Enhancing recovery in coronary heart disease (ENRICHD): baseline characteristics.” Am J Cardiol 88, no. 3 (August 1, 2001): 316–22. https://doi.org/10.1016/s0002-9149(01)01652-6.
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• Alexander, K. P., L. K. Newby, A. S. Hellkamp, R. A. Harrington, E. D. Peterson, S. Kopecky, A. Langer, et al. “Initiation of hormone replacement therapy after acute myocardial infarction is associated with more cardiac events during follow-up.” J Am Coll Cardiol 38, no. 1 (July 2001): 1–7. https://doi.org/10.1016/s0735-1097(01)01329-8.
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• Whellan, D. J., L. K. Shaw, B. A. Bart, W. E. Kraus, R. M. Califf, and C. M. O’Connor. “Cardiac rehabilitation and survival in patients with left ventricular systolic dysfunction.” Am Heart J 142, no. 1 (July 2001): 160–66. https://doi.org/10.1067/mhj.2001.115785.
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• Serebruany, V. L., C. M. O’Connor, and P. A. Gurbel. “Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease.” Am J Cardiol 87, no. 12 (June 15, 2001): 1398–1400. https://doi.org/10.1016/s0002-9149(01)01562-4.
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• Rosenberg, E. L., P. Ekman, W. Jiang, M. Babyak, R. E. Coleman, M. Hanson, C. O’Connor, R. Waugh, and J. A. Blumenthal. “Linkages between facial expressions of anger and transient myocardial ischemia in men with coronary artery disease.” Emotion 1, no. 2 (June 2001): 107–15. https://doi.org/10.1037/1528-3542.1.2.107.
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• Shah, M. R., S. S. Stinnett, S. E. McNulty, M. Gheorghiade, F. Zannad, B. Uretsky, K. F. Adams, R. M. Califf, and C. M. O’connor. “Hemodynamics as surrogate end points for survival in advanced heart failure: an analysis from FIRST.” Am Heart J 141, no. 6 (June 2001): 908–14. https://doi.org/10.1067/mhj.2001.115299.
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• Shah, M. R., V. Hasselblad, S. S. Stinnett, M. Gheorghiade, K. Swedberg, R. M. Califf, and C. M. O’Connor. “Hemodynamic profiles of advanced heart failure: association with clinical characteristics and long-term outcomes.” J Card Fail 7, no. 2 (June 2001): 105–13. https://doi.org/10.1054/jcaf.2001.24131.
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• Serebruany, V. L., P. A. Gurbel, and C. M. O’Connor. “Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors.” Pharmacol Res 43, no. 5 (May 2001): 453–62. https://doi.org/10.1006/phrs.2001.0817.
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• Shah, M. R., C. M. O’Connor, G. Sopko, V. Hasselblad, R. M. Califf, and L. W. Stevenson. “Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE): design and rationale.” Am Heart J 141, no. 4 (April 2001): 528–35. https://doi.org/10.1067/mhj.2001.113995.
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• Gurbel, P. A., C. M. O’Connor, M. R. Dalesandro, and V. L. Serebruany. “Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy.” Am J Cardiol 87, no. 6 (March 15, 2001): 774-A7. https://doi.org/10.1016/s0002-9149(00)01502-2.
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• Serebruany, V. L., A. B. Alford, A. F. Meister, S. Y. Fuzaylov, W. A. Gattis, P. A. Gurbel, and C. M. O’Connor. “Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial).” Thromb Res 101, no. 6 (March 15, 2001): 427–33. https://doi.org/10.1016/s0049-3848(00)00431-x.
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• Gattis, W. A., and C. M. O’Connor. “Effect of amlodipine on mode of death in advanced heart failure.” Cardiology Review 18, no. 2 (March 12, 2001): 13–19.
• Gattis, W. A., A. Galanos, and C. M. O’Connor. “Angiotensin-converting enzyme inhibitor dosing in heart failure: what is optimal?” Am Heart J 141, no. 3 (March 2001): 331–33. https://doi.org/10.1067/mhj.2001.113228.
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• Felker, G. M., and C. M. O’Connor. “Rational use of inotropic therapy in heart failure.” Curr Cardiol Rep 3, no. 2 (March 2001): 108–13. https://doi.org/10.1007/s11886-001-0035-8.
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• ENRICHD Investigators, P. J. “Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design.” Psychosom Med 63, no. 5 (2001): 747–55.
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• Shah, M. R., and C. M. O’connor. “The congestion score: a simple tool for a complicated disease?” Am Heart J 140, no. 6 (December 2000): 824–26. https://doi.org/10.1067/mhj.2000.110932.
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• O’Connor, C. M., W. A. Gattis, L. Shaw, M. S. Cuffe, and R. M. Califf. “Clinical characteristics and long-term outcomes of patients with heart failure and preserved systolic function.” Am J Cardiol 86, no. 8 (October 15, 2000): 863–67. https://doi.org/10.1016/s0002-9149(00)01107-3.
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• Nemeroff, C. B., and C. M. O’connor. “Introduction.” Am Heart J 140, no. 4 Suppl (October 2000): 55–56. https://doi.org/10.1067/mhj.2000.109976.
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• O’connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Depression and ischemic heart disease.” Am Heart J 140, no. 4 Suppl (October 2000): 63–69. https://doi.org/10.1067/mhj.2000.109979.
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• Varia, I., E. Logue, C. O’connor, K. Newby, H. R. Wagner, C. Davenport, K. Rathey, and K. R. Krishnan. “Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin.” Am Heart J 140, no. 3 (September 2000): 367–72. https://doi.org/10.1067/mhj.2000.108514.
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• Carson, P. A., C. M. O’Connor, A. B. Miller, S. Anderson, R. Belkin, G. W. Neuberg, J. H. Wertheimer, D. Frid, A. Cropp, and M. Packer. “Circadian rhythm and sudden death in heart failure: results from Prospective Randomized Amlodipine Survival Trial.” J Am Coll Cardiol 36, no. 2 (August 2000): 541–46. https://doi.org/10.1016/s0735-1097(00)00728-2.
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• Davis, C. J., P. A. Gurbel, W. A. Gattis, S. Y. Fuzaylov, G. V. Nair, C. M. O’Connor, and V. L. Serebruany. “Hemostatic abnormalities in patients with congestive heart failure: diagnostic significance and clinical challenge.” Int J Cardiol 75, no. 1 (August 2000): 15–21. https://doi.org/10.1016/s0167-5273(00)00300-4.
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• Kong, D. F., M. A. Blazing, and C. M. O’Connor. “Advances in the approach to acute coronary syndromes.” Hosp Pract (1995) 35, no. 4 (April 15, 2000): 61–64. https://doi.org/10.3810/hp.2000.04.192.
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• O’Connor, C. M., W. A. Gattis, and T. J. Ryan. “The role of clinical nonfatal end points in cardiovascular phase II/III clinical trials.” Am Heart J 139, no. 4 (April 2000): S143–54. https://doi.org/10.1016/s0002-8703(00)90062-0.
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• Serebruany, V. L., D. R. Lowry, S. Y. Fuzailov, D. J. Levine, C. M. O’Connor, and P. A. Gurbel. “Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction.” J Thromb Thrombolysis 9, no. 3 (April 2000): 229–34. https://doi.org/10.1023/a:1018762510842.
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• Califf, R. M., and C. M. O’Connor. “Beta-blocker therapy for heart failure: the evidence is in, now the work begins.” Jama 283, no. 10 (March 8, 2000): 1335–37. https://doi.org/10.1001/jama.283.10.1335.
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• Shah, A., G. S. Wagner, C. B. Granger, C. M. O’Connor, C. L. Green, K. M. Trollinger, R. M. Califf, and M. W. Krucoff. “Prognostic implications of TIMI flow grade in the infarct related artery compared with continuous 12-lead ST-segment resolution analysis. Reexamining the "gold standard" for myocardial reperfusion assessment.” J Am Coll Cardiol 35, no. 3 (March 1, 2000): 666–72. https://doi.org/10.1016/s0735-1097(99)00601-4.
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• Gurbel, P. A., D. J. Kereiakes, M. R. Dalesandro, R. D. Bahr, C. M. O’Connor, and V. L. Serebruany. “Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.” Am Heart J 139, no. 2 Pt 1 (February 2000): 320–28. https://doi.org/10.1067/mhj.2000.101109.
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• Bosworth, H. B., D. C. Steffens, M. N. Kuchibhatla, W. J. Jiang, R. M. Arias, C. M. O’Connor, and K. R. R. Krishnan. “The relationship of social support, social networks and negative events with depression in patients with coronary artery disease.” Aging and Mental Health 4, no. 3 (January 1, 2000): 253–58. https://doi.org/10.1080/713649927.
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• Gattis, W., and C. M. O’Connor. “[Calcium antagonists in the treatment of heart failure. Re-evaluation of therapeutic strategies].” Drugs 59 Spec No 2 (2000): 17–24.
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• Gattis, W., and C. M. O’Connor. “Calcium antagonist use in heart failure: A re-evalutaion of treatment options.” Drugs 59, no. SPEC. ISS. 2 (January 1, 2000): 17–24. https://doi.org/10.2165/00003495-200059992-00003.
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• Gurbel, P. A., D. J. Kereiakes, M. R. Dalesandro, R. D. Bahr, C. M. O’Connor, and V. L. Serebruany. “Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.” American Heart Journal 139, no. 2 I (2000): 320–28.
• Cuffe, M. S., R. M. Califf, K. F. Adams, R. C. Bourge, W. Colucci, B. Massie, C. M. O’Connor, et al. “Rationale and design of the OPTIME CHF trial: outcomes of a prospective trial of intravenous milrinone for exacerbations of chronic heart failure.” Am Heart J 139, no. 1 Pt 1 (January 2000): 15–22. https://doi.org/10.1016/s0002-8703(00)90303-x.
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• Fortner, Molly R., Kristine Brown, Indu M. Varia, Kenneth R. Gersing, Christopher O’Connor, and P Murali Doraiswamy. “Effect of Bupropion SR on the Quality of Life of Elderly Depressed Patients With Comorbid Medical Disorders.” Prim Care Companion J Clin Psychiatry 1, no. 6 (December 1999): 174–79. https://doi.org/10.4088/pcc.v01n0601.
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• O’Connor, C. M., W. A. Gattis, M. Gheorghiade, C. B. Granger, J. Gilbert, J. M. McKenney, F. C. Messineo, et al. “A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: the U.S. ecadotril pilot safety study.” Am Heart J 138, no. 6 Pt 1 (December 1999): 1140–48. https://doi.org/10.1016/s0002-8703(99)70081-5.
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• Velazquez, E. J., and C. M. O’Connor. “Heart failure after myocardial infarction: A good heart is hard to find.” Am Heart J 138, no. 6 Pt 1 (December 1999): 1009–11. https://doi.org/10.1016/s0002-8703(99)70061-x.
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• Orloff, D. G., M. A. Blazing, and C. M. O’Connor. “Atherosclerotic disease in non-insulin-dependent diabetes mellitus: role of abnormal lipids and the place for lipid-altering therapies.” Am Heart J 138, no. 5 Pt 1 (November 1999): S406–12. https://doi.org/10.1016/s0002-8703(99)70043-8.
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• Del Carlo, C. H., and C. M. O’Connor. “Cardiac troponins in congestive heart failure.” Am Heart J 138, no. 4 Pt 1 (October 1999): 646–53. https://doi.org/10.1016/s0002-8703(99)70178-x.
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• Doraiswamy, P. M., J. MacFall, K. R. Krishnan, C. O’Connor, X. Wan, M. Benaur, M. Lewandowski, and M. Fortner. “Magnetic resonance assessment of cerebral perfusion in depressed cardiac patients: preliminary findings.” Am J Psychiatry 156, no. 10 (October 1999): 1641–43. https://doi.org/10.1176/ajp.156.10.1641.
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• Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada. The CARS Investigators (Coumadin/Aspirin Reinfarction Study).” The Canadian Journal of Cardiology 15, no. 10 (October 1999): 1095–1102.
• Langer, A., M. Fisher, R. M. Califf, S. Goodman, C. M. O’Connor, R. A. Harrington, and V. Fuster. “Higher rates of coronary angiography and revascularization following myocardial infarction may be associated with greater survival in the United States than in Canada.” Canadian Journal of Cardiology 15, no. 10 (October 1, 1999): 1095–1102.
• Gattis, W. A., V. Hasselblad, D. J. Whellan, and C. M. O’Connor. “Reduction in heart failure events by the addition of a clinical pharmacist to the heart failure management team: results of the Pharmacist in Heart Failure Assessment Recommendation and Monitoring (PHARM) Study.” Arch Intern Med 159, no. 16 (September 13, 1999): 1939–45. https://doi.org/10.1001/archinte.159.16.1939.
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• Gurbel, P. A., C. M. O’Connor, C. C. Cummings, and V. L. Serebruany. “Clopidogrel: the future choice for preventing platelet activation during coronary stenting?” Pharmacol Res 40, no. 2 (August 1999): 107–11. https://doi.org/10.1006/phrs.1999.0478.
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• Serebruany, V. L., S. R. Murugesan, A. Pothula, D. Atar, D. R. Lowry, C. M. O’Connor, and P. A. Gurbel. “Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy.” Eur J Heart Fail 1, no. 3 (August 1999): 243–49. https://doi.org/10.1016/s1388-9842(99)00029-x.
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• Nair, G. V., P. A. Gurbel, C. M. O’Connor, W. A. Gattis, S. R. Murugesan, and V. L. Serebruany. “Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors.” Am J Cardiol 84, no. 3 (August 1, 1999): 321-A8. https://doi.org/10.1016/s0002-9149(99)00284-2.
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• Blazing, M. A., and C. M. O’Connor. “Evidence supporting secondary prevention strategies.” Curr Opin Cardiol 14, no. 4 (July 1999): 303–9. https://doi.org/10.1097/00001573-199907000-00005.
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• O’Connor, C. M., P. W. Radensky, A. N. Unger, and B. C. Martin. “Hospital use and costs among patients with nonischemic cardiomyopathy in the first prospective randomized amlodipine survival evaluation study.” Clin Ther 21, no. 7 (July 1999): 1254–65. https://doi.org/10.1016/S0149-2918(00)80027-2.
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• O’Connor, C. M., W. A. Gattis, B. F. Uretsky, K. F. Adams, S. E. McNulty, S. H. Grossman, W. J. McKenna, et al. “Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST).” Am Heart J 138, no. 1 Pt 1 (July 1999): 78–86. https://doi.org/10.1016/s0002-8703(99)70250-4.
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• Shapiro, P. A., F. Lespérance, N. Frasure-Smith, C. M. O’Connor, B. Baker, J. W. Jiang, P. Dorian, W. Harrison, and A. H. Glassman. “An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT Trial). Sertraline Anti-Depressant Heart Attack Trial.” Am Heart J 137, no. 6 (June 1999): 1100–1106. https://doi.org/10.1016/s0002-8703(99)70369-8.
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• Kong, D. F., M. A. Blazing, and C. M. O’Connor. “The health care burden of unstable angina.” Cardiol Clin 17, no. 2 (May 1999): 247–61. https://doi.org/10.1016/s0733-8651(05)70072-2.
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• O’Connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure.” Am J Cardiol 83, no. 9 (May 1, 1999): 1345–49. https://doi.org/10.1016/s0002-9149(99)00098-3.
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• Adams, K. F., C. A. Sueta, M. Gheorghiade, C. M. O’Connor, T. A. Schwartz, G. G. Koch, B. Uretsky, et al. “Gender differences in survival in advanced heart failure. Insights from the FIRST study.” Circulation 99, no. 14 (April 13, 1999): 1816–21. https://doi.org/10.1161/01.cir.99.14.1816.
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• Whellan, D. J., W. A. Gattis, L. Gaulden, B. Granger, and C. M. O’Connor. “Disease management of congestive heart failure.” The American Journal of Managed Care 5, no. 4 (April 1999): 499–507.
• O’Connor, C. M., W. A. Gattis, F. Zannad, S. E. McNulty, M. Gheorghiade, K. F. Adams, R. M. Califf, W. J. McKenna, J. Soler-Soler, and K. Swedberg. “Beta-blocker therapy in advanced heart failure: clinical characteristics and long-term outcomes.” European Journal of Heart Failure 1, no. 1 (March 1999): 81–88. https://doi.org/10.1016/s1388-9842(98)00004-x.
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• Steffens, D. C., C. M. O’Connor, W. J. Jiang, C. F. Pieper, M. N. Kuchibhatla, R. M. Arias, A. Look, C. Davenport, M. B. Gonzalez, and K. R. Krishnan. “The effect of major depression on functional status in patients with coronary artery disease.” J Am Geriatr Soc 47, no. 3 (March 1999): 319–22. https://doi.org/10.1111/j.1532-5415.1999.tb02995.x.
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• Bart, B. A., and C. M. O’Connor. “Clinical determinants of mortality in patients with cardiomyopathy.” Cardiology Review 16, no. 7 (January 1, 1999): 8–11.
• McKenzie, M. E., A. Pothula, P. A. Gurbel, S. Y. Fuzaylov, C. M. O’Connor, W. A. Gattis, and V. L. Serebruany. “Failure of thrombin generation markers to triage patients presenting with chest pain.” Cardiology 92, no. 1 (1999): 53–58. https://doi.org/10.1159/000006946.
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• Thel, M. C., and C. M. O’Connor. “Cardiopulmonary resuscitation: historical perspective to recent investigations.” Am Heart J 137, no. 1 (January 1999): 39–48. https://doi.org/10.1016/s0002-8703(99)70458-8.
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• O’Connor, C. M., W. A. Gattis, and K. Swedberg. “Current and novel pharmacologic approaches in advanced heart failure.” Heart Lung 28, no. 4 (1999): 227–42. https://doi.org/10.1016/s0147-9563(99)70069-5.
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• O’Connor, C. M., P. E. Carson, A. B. Miller, M. L. Pressler, R. N. Belkin, G. W. Neuberg, D. J. Frid, et al. “Effect of amlodipine on mode of death among patients with advanced heart failure in the PRAISE trial. Prospective Randomized Amlodipine Survival Evaluation.” Am J Cardiol 82, no. 7 (October 1, 1998): 881–87. https://doi.org/10.1016/s0002-9149(98)00496-2.
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• Guyton, J. R., A. C. Goldberg, R. A. Kreisberg, D. L. Sprecher, H. R. Superko, and C. M. O’Connor. “Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia.” Am J Cardiol 82, no. 6 (September 15, 1998): 737–43. https://doi.org/10.1016/s0002-9149(98)00448-2.
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• Krishnan, K. R., L. K. George, C. F. Pieper, W. Jiang, R. Arias, A. Look, and C. O’Connor. “Depression and social support in elderly patients with cardiac disease.” Am Heart J 136, no. 3 (September 1998): 491–95. https://doi.org/10.1016/s0002-8703(98)70225-x.
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• Shah, B. R., C. Lin, C. Maynard, B. Bart, R. H. Selvester, L. K. Shaw, C. O’Connor, and G. S. Wagner. “Specificity of electrocardiographic myocardial infarction screening criteria in patients with nonischemic cardiomyopathies.” Am Heart J 136, no. 2 (August 1998): 314–19. https://doi.org/10.1053/hj.1998.v136.89909.
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• Gattis, W. A., R. L. Larsen, V. Hasselblad, B. A. Bart, and C. M. O’Connor. “Is optimal angiotensin-converting enzyme inhibitor dosing neglected in elderly patients with heart failure?” Am Heart J 136, no. 1 (July 1998): 43–48. https://doi.org/10.1016/s0002-8703(98)70180-2.
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• Serebruany, V. L., R. D. Bahr, C. M. O’Connor, D. R. Lowry, and P. A. Gurbel. “Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction. The GUSTO-III Platelet Substudy.” Cardiology 90, no. 1 (July 1998): 37–42. https://doi.org/10.1159/000006814.
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• Serebruany, V. L., D. Atar, M. R. Dalesandro, C. M. O’Connor, and P. A. Gurbel. “Changes in hemostasis after parenteral magnesium in myocardial ischemia-reperfusion: from animal studies to clinical trials.” Magnes Res 11, no. 2 (June 1998): 133–40.
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• O’Connor, C. M., W. A. Gattis, and K. Swedberg. “Current and novel pharmacologic approaches in advanced heart failure.” Am Heart J 135, no. 6 Pt 2 Su (June 1998): S249–63. https://doi.org/10.1016/s0002-8703(98)70254-6.
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• Flack, J. M., C. M. O’Connor, and J. Y. Wei. “Four commonly seen cardiovascular diseases.” Patient Care 32, no. 9 (May 15, 1998): 98–130.
• Hassan, T. B., and D. B. Barnett. “Magnesium in in-hospital cardiac arrest.” Lancet 351, no. 9100 (February 7, 1998): 445–46. https://doi.org/10.1016/S0140-6736(05)78390-2.
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• Cuffe, M. S., and C. M. O’Connor. “Pharmacologic management of acute heart failure.” Current Opinion in Critical Care 3, no. 5 (December 1, 1997): 386–90.
• Thel, M. C., A. L. Armstrong, S. E. McNulty, R. M. Califf, and C. M. O’Connor. “Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff.” Lancet 350, no. 9087 (November 1, 1997): 1272–76. https://doi.org/10.1016/s0140-6736(97)05048-4.
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• Blumenthal, J. A., W. Jiang, M. A. Babyak, D. S. Krantz, D. J. Frid, R. E. Coleman, R. Waugh, et al. “Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms.” Arch Intern Med 157, no. 19 (October 27, 1997): 2213–23.
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• Bart, B. A., L. K. Shaw, C. B. McCants, D. F. Fortin, K. L. Lee, R. M. Califf, and C. M. O’Connor. “Clinical determinants of mortality in patients with angiographically diagnosed ischemic or nonischemic cardiomyopathy.” J Am Coll Cardiol 30, no. 4 (October 1997): 1002–8. https://doi.org/10.1016/s0735-1097(97)00235-0.
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• Jiang, W., W. R. Hathaway, S. McNulty, R. L. Larsen, K. L. Hansley, Y. Zhang, and C. M. O’Connor. “Ability of heart rate variability to predict prognosis in patients with advanced congestive heart failure.” Am J Cardiol 80, no. 6 (September 15, 1997): 808–11. https://doi.org/10.1016/s0002-9149(97)00526-2.
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• Hayano, J., W. Jiang, R. Waugh, C. O’Connor, D. Frid, and J. A. Blumenthal. “Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease.” Am Heart J 134, no. 3 (September 1997): 411–18. https://doi.org/10.1016/s0002-8703(97)70075-9.
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• O’Connor, C. M., W. R. Hathaway, E. R. Bates, J. D. Leimberger, K. N. Sigmon, D. J. Kereiakes, B. S. George, et al. “Clinical characteristics and long-term outcome of patients in whom congestive heart failure develops after thrombolytic therapy for acute myocardial infarction: development of a predictive model.” Am Heart J 133, no. 6 (June 1997): 663–73. https://doi.org/10.1016/s0002-8703(97)70168-6.
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• Gullette, E. C., J. A. Blumenthal, M. Babyak, W. Jiang, R. A. Waugh, D. J. Frid, C. M. O’Connor, J. J. Morris, and D. S. Krantz. “Effects of mental stress on myocardial ischemia during daily life.” Jama 277, no. 19 (May 21, 1997): 1521–26.
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• Bart, B. A., W. A. Gattis, S. J. Diem, and C. M. O’Connor. “Reasons for underuse of angiotensin-converting enzyme inhibitors in patients with heart failure and left ventricular dysfunction.” Am J Cardiol 79, no. 8 (April 15, 1997): 1118–20. https://doi.org/10.1016/s0002-9149(97)00060-x.
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• Allan, J. J. “Amlodipine in chronic heart failure.” N Engl J Med 336, no. 14 (April 3, 1997): 1023–24.
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• Blumenthal, J. A., C. O’Connor, A. Hinderliter, K. Fath, S. B. Hegde, G. Miller, J. Puma, et al. “Psychosocial factors and coronary disease. A national multicenter clinical trial (ENRICHD) with a North Carolina focus.” N C Med J 58, no. 6 (1997): 440–44.
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• Packer, M., C. M. O’Connor, J. K. Ghali, M. L. Pressler, P. E. Carson, R. N. Belkin, A. B. Miller, et al. “Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group.” N Engl J Med 335, no. 15 (October 10, 1996): 1107–14. https://doi.org/10.1056/NEJM199610103351504.
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• Barefoot, J. C., M. J. Helms, D. B. Mark, J. A. Blumenthal, R. M. Califf, T. L. Haney, C. M. O’Connor, I. C. Siegler, and R. B. Williams. “Depression and long-term mortality risk in patients with coronary artery disease.” Am J Cardiol 78, no. 6 (September 15, 1996): 613–17. https://doi.org/10.1016/s0002-9149(96)00380-3.
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• Jiang, W., M. Babyak, D. S. Krantz, R. A. Waugh, R. E. Coleman, M. M. Hanson, D. J. Frid, et al. “Mental stress--induced myocardial ischemia and cardiac events.” Jama 275, no. 21 (June 5, 1996): 1651–56. https://doi.org/10.1001/jama.275.21.1651.
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• O’Connor, C. M., R. B. Meese, S. McNulty, K. D. Lucas, R. J. Carney, R. M. LeBoeuf, W. Maddox, et al. “A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction. The DUCCS-II Investigators.” Am J Cardiol 77, no. 10 (April 15, 1996): 791–97. https://doi.org/10.1016/s0002-9149(97)89171-0.
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• Mahaffey, K. W., C. B. Granger, R. Collins, C. M. O’Connor, E. M. Ohman, S. D. Bleich, J. J. Col, and R. M. Califf. “Overview of randomized trials of intravenous heparin in patients with acute myocardial infarction treated with thrombolytic therapy.” Am J Cardiol 77, no. 8 (March 15, 1996): 551–56. https://doi.org/10.1016/s0002-9149(97)89305-8.
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• Gonzalez, M. B., T. B. Snyderman, J. T. Colket, R. M. Arias, J. W. Jiang, C. M. O’Connor, and K. R. Krishnan. “Depression in patients with coronary artery disease.” Depression 4, no. 2 (1996): 57–62. https://doi.org/10.1002/(SICI)1522-7162(1996)4:2<57::AID-DEPR3>3.0.CO;2-C.
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• Blumenthal, J. A., W. Jiang, R. A. Waugh, D. J. Frid, J. J. Morris, R. E. Coleman, M. Hanson, M. Babyak, E. T. Thyrum, and D. S. Krantz. “Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life. Association and hemodynamic features.” Circulation 92, no. 8 (October 15, 1995): 2102–8. https://doi.org/10.1161/01.cir.92.8.2102.
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• Thel, M. C., and C. M. O’Connor. “Magnesium in acute myocardial infarction.” Coron Artery Dis 6, no. 10 (October 1995): 831–37. https://doi.org/10.1097/00019501-199510000-00012.
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• Jiang, W., J. A. Blumenthal, M. W. Hanson, R. E. Coleman, C. M. O’Connor, D. Frid, J. J. Morris, and R. A. Waugh. “Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring.” Am J Cardiol 76, no. 5 (August 15, 1995): 350–54. https://doi.org/10.1016/s0002-9149(99)80099-x.
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• Mörike, K., and G. Mikus. “Zofenopril after anterior myocardial infarction.” N Engl J Med 332, no. 25 (June 22, 1995): 1715.
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• Campbell, P. T., J. S. Li, T. C. Wall, C. M. O’Connor, P. Van Trigt, R. T. Kenney, O. Melhus, and G. R. Corey. “Cytomegalovirus pericarditis: a case series and review of the literature.” Am J Med Sci 309, no. 4 (April 1995): 229–34. https://doi.org/10.1097/00000441-199504000-00009.
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• Jiang, W., M. A. Trauner, R. E. Coleman, R. A. Waugh, M. W. Hanson, D. J. Frid, B. G. Phillips, J. J. Morris, C. O’Connor, and J. A. Blumenthal. “Association of physical fitness and transient myocardial ischemia in patients with coronary artery disease.” J Cardiopulm Rehabil 15, no. 6 (1995): 431–38. https://doi.org/10.1097/00008483-199511000-00007.
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• Selker, H. P., J. R. Beshansky, C. H. Schmid, J. L. Griffith, W. T. Longstreth, C. M. O’Connor, L. R. Caplan, E. W. Massey, R. B. D’Agostino, and M. M. Laks. “Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results.” Circulation 90, no. 4 (October 1994): 1657–61. https://doi.org/10.1161/01.cir.90.4.1657.
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• Larsen, R. L., V. S. Behar, S. R. Brazer, J. Chen, and C. M. O’Connor. “Chest pain presenting as ischemic heart disease. Congenital absence of the pericardium.” N C Med J 55, no. 7 (July 1994): 306–8.
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• O’Connor, C. M., R. Meese, R. Carney, J. Smith, E. Conn, J. Burks, C. Hartman, S. Roark, N. Shadoff, and M. Heard. “A randomized trial of intravenous heparin in conjunction with anistreplase (anisoylated plasminogen streptokinase activator complex) in acute myocardial infarction: the Duke University Clinical Cardiology Study (DUCCS) 1.” J Am Coll Cardiol 23, no. 1 (January 1994): 11–18. https://doi.org/10.1016/0735-1097(94)90496-0.
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• Van Trigt, P., J. Douglas, P. K. Smith, P. T. Campbell, T. C. Wall, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, and G. R. Corey. “A prospective trial of subxiphoid pericardiotomy in the diagnosis and treatment of large pericardial effusion. A follow-up report.” Ann Surg 218, no. 6 (December 1993): 777–82. https://doi.org/10.1097/00000658-199312000-00012.
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• Jiang, W., J. Hayano, E. R. Coleman, M. W. Hanson, D. J. Frid, C. O’Connor, D. Thurber, R. A. Waugh, and J. A. Blumenthal. “Relation of cardiovascular responses to mental stress and cardiac vagal activity in coronary artery disease.” Am J Cardiol 72, no. 7 (September 1, 1993): 551–54. https://doi.org/10.1016/0002-9149(93)90350-l.
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• Corey, G. R., P. T. Campbell, P. Van Trigt, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, J. A. Kisslo, and T. C. Wall. “Etiology of large pericardial effusions.” Am J Med 95, no. 2 (August 1993): 209–13. https://doi.org/10.1016/0002-9343(93)90262-n.
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• Kenney, R. T., J. S. Li, W. A. Clyde, T. C. Wall, C. M. O’Connor, P. T. Campbell, P. Van Trigt, and G. R. Corey. “Mycoplasmal pericarditis: evidence of invasive disease.” Clin Infect Dis 17 Suppl 1 (August 1993): S58–62. https://doi.org/10.1093/clinids/17.supplement_1.s58.
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• Krucoff, M. W., M. A. Croll, J. E. Pope, C. B. Granger, C. M. O’Connor, K. N. Sigmon, B. L. Wagner, J. A. Ryan, K. L. Lee, and D. J. Kereiakes. “Continuous 12-lead ST-segment recovery analysis in the TAMI 7 study. Performance of a noninvasive method for real-time detection of failed myocardial reperfusion.” Circulation 88, no. 2 (August 1993): 437–46. https://doi.org/10.1161/01.cir.88.2.437.
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• Slaughter, T. F., E. A. Mody, H. N. Oldham, J. G. Reves, C. M. O’Connor, J. K. Parker, and C. S. Greenberg. “Management of a patient with type IIC von Willebrand's disease during coronary artery bypass graft surgery.” Anesthesiology 78, no. 1 (January 1993): 195–97. https://doi.org/10.1097/00000542-199301000-00027.
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• Wall, T. C., P. T. Campbell, C. M. O’Connor, P. Van Trigt, R. T. Kenney, K. H. Sheikh, J. A. Kisslo, and G. R. Corey. “Diagnosis and management (by subxiphoid pericardiotomy) of large pericardial effusions causing cardiac tamponade.” Am J Cardiol 69, no. 12 (April 15, 1992): 1075–78. https://doi.org/10.1016/0002-9149(92)90866-w.
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• Campbell, P. T., P. Van Trigt, T. C. Wall, R. T. Kenney, C. M. O’Connor, K. H. Sheikh, J. A. Kisslo, M. E. Baker, and G. R. Corey. “Subxiphoid pericardiotomy in the diagnosis and management of large pericardial effusions associated with malignancy.” Chest 101, no. 4 (April 1992): 938–43. https://doi.org/10.1378/chest.101.4.938.
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• Ortel, T. L., J. P. Gockerman, R. M. Califf, R. L. McCann, C. M. O’Connor, D. M. Metzler, and C. S. Greenberg. “Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.” Thromb Haemost 67, no. 3 (March 2, 1992): 292–96.
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• O’Connor, C. M., and R. M. Califf. “Aggressive therapy of acute MI in the elderly.” Hospital Practice (Office Ed.) 27, no. 2 (February 1992): 59-passim. https://doi.org/10.1080/21548331.1992.11705360.
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• Uglietta, J. P., C. M. O’Connor, O. B. Boyko, H. Aldrich, E. W. Massey, and E. R. Heinz. “CT patterns of intracranial hemorrhage complicating thrombolytic therapy for acute myocardial infarction.” Radiology 181, no. 2 (November 1991): 555–59. https://doi.org/10.1148/radiology.181.2.1924804.
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• Wallis, D. E., W. E. Boden, R. Califf, M. H. Crawford, A. H. Hakki, A. S. Iskandrian, A. Labovitz, C. O’Connor, R. Sutton, and P. J. Scanlon. “Failure of adjuvant heparin to reduce myocardial ischemia in the early treatment of patients with unstable angina.” Am Heart J 122, no. 4 Pt 1 (October 1991): 949–54. https://doi.org/10.1016/0002-8703(91)90456-r.
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• O’Connor, C. M., R. M. Califf, E. W. Massey, D. B. Mark, D. J. Kereiakes, R. J. Candela, C. Abbottsmith, B. George, R. S. Stack, and L. Aronson. “Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis.” J Am Coll Cardiol 16, no. 3 (September 1990): 533–40. https://doi.org/10.1016/0735-1097(90)90338-p.
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• Blumenthal, J. A., and C. O’Connor. “Stress and silent myocardial ischemia. A new research study at Duke University Medical Center.” N C Med J 51, no. 4 (April 1990): 135–38.
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• Mark, D. B., M. A. Hlatky, C. M. O’Connor, D. B. Pryor, T. C. Wall, M. B. Honan, H. R. Phillips, and R. M. Califf. “Administration of thrombolytic therapy in the community hospital: established principles and unresolved issues.” J Am Coll Cardiol 12, no. 6 Suppl A (December 1988): 32A-43A. https://doi.org/10.1016/0735-1097(88)92639-3.
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• Stack, R. S., R. M. Califf, T. Hinohara, H. R. Phillips, D. B. Pryor, C. A. Simonton, E. B. Carlson, K. G. Morris, V. S. Behar, and Y. Kong. “Survival and cardiac event rates in the first year after emergency coronary angioplasty for acute myocardial infarction.” J Am Coll Cardiol 11, no. 6 (June 1988): 1141–49. https://doi.org/10.1016/0735-1097(88)90274-4.
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• Simonton, C. A., D. B. Mark, T. Hinohara, D. S. Rendall, H. R. Phillips, R. H. Peter, V. S. Behar, Y. Kong, W. G. O’Callaghan, and C. O’Connor. “Late restenosis after emergent coronary angioplasty for acute myocardial infarction: comparison with elective coronary angioplasty.” J Am Coll Cardiol 11, no. 4 (April 1988): 698–705. https://doi.org/10.1016/0735-1097(88)90198-2.
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• Hlatky, M. A., H. Cotugno, C. O’Connor, D. B. Mark, D. B. Pryor, and R. M. Califf. “Adoption of thrombolytic therapy in the management of acute myocardial infarction.” Am J Cardiol 61, no. 8 (March 1, 1988): 510–14. https://doi.org/10.1016/0002-9149(88)90755-2.
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• Hlatky, M. A., H. E. Cotugno, D. B. Mark, C. O’Connor, R. M. Califf, and D. B. Pryor. “Trends in physician management of uncomplicated acute myocardial infarction, 1970 to 1987.” Am J Cardiol 61, no. 8 (March 1, 1988): 515–18. https://doi.org/10.1016/0002-9149(88)90756-4.
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• Stack, R. S., C. M. O’Connor, D. B. Mark, T. Hinohara, H. R. Phillips, M. M. Lee, N. M. Ramirez, W. G. O’Callaghan, C. A. Simonton, and E. B. Carlson. “Coronary perfusion during acute myocardial infarction with a combined therapy of coronary angioplasty and high-dose intravenous streptokinase.” Circulation 77, no. 1 (January 1988): 151–61. https://doi.org/10.1161/01.cir.77.1.151.
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• Boswick, J. M., K. L. Lee, L. G. Aronson, C. M. O’Connor, M. B. Honan, R. M. Califf, and D. B. Pryor. “USE OF COMPUTERIZED STATISTICAL MODELS TO EDUCATE MEDICAL HOUSESTAFF IN ESTIMATING CLINICAL OUTCOMES.” Proceedings  Annual Symposium on Computer Applications in Medical Care, December 1, 1987, 162–65.
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• Brooks, R. A., L. G. Mitchell, C. M. O’Connor, and G. Di Chiro. “On the relationship between computed tomography numbers and specific gravity.” Phys Med Biol 26, no. 1 (January 1981): 141–47. https://doi.org/10.1088/0031-9155/26/1/014.
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• Rieth, K. G., K. Fujiwara, G. Di Chiro, I. Klatzo, R. A. Brooks, G. S. Johnston, C. M. O’Connor, and L. G. Mitchell. “Serial measurements of CT attenuation and specific gravity in experimental cerebral edema.” Radiology 135, no. 2 (May 1980): 343–48. https://doi.org/10.1148/radiology.135.2.6768102.
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• Koenig, Harold G., Christopher M. O’Connor, Steven A. Guarisco, K Michael Zabel, and Stephen M. Ford. “Depressive Disorder in Older Medical Inpatients on General Medicine and Cardiology Services at a University Teaching Hospital.” Am J Geriatr Psychiatry 1, no. 3 (n.d.): 197–210. https://doi.org/10.1097/00019442-199300130-00004.
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