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Christopher Michael O'Connor

Adjunct Professor in the Department of Medicine
Medicine, Clinical Pharmacology
Duke Box 3356, Durham, NC 27710
7401 Hosp North, Durham, NC 27710

Overview


Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.

Current Appointments & Affiliations


Adjunct Professor in the Department of Medicine · 2016 - Present Medicine, Clinical Pharmacology, Medicine

In the News


Published November 19, 2019
Global List of Highly Cited Puts Duke in Top Ten
Published November 27, 2018
Duke Faculty Plentiful On ‘Highly Cited’ List

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Recent Publications


Standardized Definitions of Changes in Kidney Function in Trials of Heart Failure: JACC Expert Panel From the HF-ARC.

Journal Article J Am Coll Cardiol · February 25, 2025 Perturbations in kidney function are frequently encountered in heart failure (HF) across its spectrum in both chronic and acute settings with distinct implications for patient management and prognosis. Lack of consensus on the threshold for clinically mean ... Full text Link to item Cite

Baseline characteristics of contemporary trial participants with heart failure and reduced ejection fraction: The VICTOR trial.

Journal Article Eur J Heart Fail · February 16, 2025 AIMS: To describe the baseline characteristics of the participants in the VICTOR (Vericiguat Global Study in Patients with Chronic Heart Failure; NCT05093933) trial and compare them to recent trials in patients with heart failure and reduced ejection fract ... Full text Link to item Cite

Characterization of ischemic etiology in heart failure with reduced ejection fraction randomized clinical trials: A systematic review and meta-analysis.

Journal Article Eur J Intern Med · February 11, 2025 AIMS: We investigated how ischemic etiology has been assigned in heart failure with a reduced ejection fraction (HFrEF) randomized controlled trials (RCTs). METHODS AND RESULTS: We performed a systematic review and meta-analysis of definitions, rates of is ... Full text Link to item Cite
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Recent Grants


Duke-UNC Clinical Hematology and Transfusion Research Career Development Program

ResearchMentor · Awarded by National Institutes of Health · 2006 - 2019

STICHES

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2011 - 2019

GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC)

ResearchCo Investigator · Awarded by National Institutes of Health · 2012 - 2017

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Education, Training & Certifications


University of Maryland, College Park · 1983 M.D.