Overview
Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.
Current Appointments & Affiliations
Adjunct Professor in the Department of Medicine
·
2016 - Present
Medicine, Clinical Pharmacology,
Medicine
Recent Publications
Background Therapy for HF Clinical Trials: A Randomized Crossover Debate From the Heart Failure Collaboratory.
Journal Article JACC Heart Fail · October 2025 Full text Link to item CiteBlood pressure, safety and clinical efficacy of vericiguat in chronic heart failure with reduced ejection fraction: Insights from the VICTOR trial.
Journal Article Eur J Heart Fail · September 29, 2025 AIMS: The efficacy and safety of vericiguat in patients with chronic heart failure with reduced ejection fraction (HFrEF) on contemporary heart failure (HF) therapies and without recent worsening was investigated in the VICTOR trial, yet some subgroups may ... Full text Link to item CiteVericiguat for patients with heart failure and reduced ejection fraction across the risk spectrum: an individual participant data analysis of the VICTORIA and VICTOR trials.
Journal Article Lancet · September 27, 2025 BACKGROUND: Following completion of the VICTORIA trial, vericiguat was approved for the treatment of worsening heart failure with reduced ejection fraction (HFrEF) and received a class IIb recommendation in European and North American guidelines. The subse ... Full text Link to item CiteRecent Grants
Duke-UNC Clinical Hematology and Transfusion Research Career Development Program
ResearchMentor · Awarded by National Institutes of Health · 2006 - 2019STICHES
Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2011 - 2019GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC)
ResearchCo Investigator · Awarded by National Institutes of Health · 2012 - 2017View All Grants
Education, Training & Certifications
University of Maryland, College Park ·
1983
M.D.