Current Appointments & Affiliations
Statistician II
Center for Population Health & Aging,
Duke Population Research Institute
Recent Publications
Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits.
Journal Article Aging cell · February 2017 Traditionally, genomewide association studies (GWAS) have emphasized the benefits of large samples in the analyses of age-related traits rather than their specific properties. We adopted a realistic concept of genetic susceptibility to inherently heterogen ... Full text Open Access CiteHigh-Resolution Analyses of Effects of Polygenic Risk Scores on Time-to-Event Outcomes in Longitudinal Studies
Conference GENETIC EPIDEMIOLOGY · November 1, 2016 Link to item CitePleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality.
Journal Article PLoS genetics · November 2016 Gaining insights into genetic predisposition to age-related diseases and lifespan is a challenging task complicated by the elusive role of evolution in these phenotypes. To gain more insights, we combined methods of genome-wide and candidate-gene studies. ... Full text CiteRecent Grants
Leveraging population-based human data to uncover mechanisms connecting Alzheimer's disease and common infections and facilitate vaccines repurposing for AD prevention
ResearchStatistician · Awarded by National Institutes of Health · 2021 - 2026Understanding Alzheimer's Disease in the Context of the Aging
ResearchStatistician · Awarded by National Institutes of Health · 2019 - 2025Project 1: The Long Life Family Study
ResearchSenior Research Scientist · Awarded by Washington University in St. Louis · 2019 - 2025View All Grants