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Ophelia Shalini Venturelli

Associate Professor in the Department of Biomedical Engineering
Biomedical Engineering

Research Interests


Systems biology, synthetic biology, computational modeling, microbiomes, host-microbiome interactions, microbial metabolism

Selected Grants


A multi-scale systems biology framework for understanding and engineering the human gut microbiome

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2030

Dietary Fiber-Microbiome Interactions: Elucidating Mechanisms to Suppress Multi-Drug Resistant Organisms in the Human Gut

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2025 - 2029

NSF Engineering Research Center for Precision Microbiome Engineering (PreMiEr)

ResearchInvestigator · Awarded by National Science Foundation · 2022 - 2027

Duke Training Grant in Digestive Diseases and Nutrition

Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 1988 - 2027

Accelerating microbial community metabolism with physics-integrated active machine learning

ResearchPrincipal Investigator · Awarded by Defense Advanced Research Projects Agency · 2025 - 2026

A Systems Understanding of Nitrogen-fixation on the Aerial Roots of Sorghum

ResearchPrincipal Investigator · Awarded by University of Wisconsin - Madison · 2024 - 2025

Integrating physics and machine learning to design stable microbial communities

ResearchPrincipal Investigator · Awarded by Defense Advanced Research Projects Agency · 2024 - 2025

Investigating energy efficiency, information processing and control architectures of microbial community interaction networks

ResearchPrincipal Investigator · Awarded by University of Southern California · 2024 - 2025