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Palen Powelson Mallory

Assistant Professor of Pediatrics
Pediatrics, Critical Care Medicine

Selected Publications


Evaluating Airway Management in Patients With Trisomy 21 in the PICU and Cardiac ICU: A Retrospective Cohort Study.

Journal Article Pediatr Crit Care Med · April 1, 2024 OBJECTIVES: Children with trisomy 21 often have anatomic and physiologic features that may complicate tracheal intubation (TI). TI in critically ill children with trisomy 21 is not well described. We hypothesize that in children with trisomy 21, TI is asso ... Full text Link to item Cite

Ketamine Use in the Intubation of Critically Ill Children with Neurological Indications: A Multicenter Retrospective Analysis.

Journal Article Neurocrit Care · February 2024 BACKGROUND: Ketamine has traditionally been avoided for tracheal intubations (TIs) in patients with acute neurological conditions. We evaluate its current usage pattern in these patients and any associated adverse events. METHODS: We conducted a retrospect ... Full text Link to item Cite

Adverse Tracheal Intubation Events in Critically Ill Underweight and Obese Children: Retrospective Study of the National Emergency Airway for Children Registry (2013-2020).

Journal Article Pediatr Crit Care Med · February 1, 2024 OBJECTIVES: Extremes of patient body mass index are associated with difficult intubation and increased morbidity in adults. We aimed to determine the association between being underweight or obese with adverse airway outcomes, including adverse tracheal in ... Full text Link to item Cite

Tracheal Intubation by Advanced Practice Registered Nurses in Pediatric Critical Care: Retrospective Study From the National Emergency Airway for Children Registry (2015-2019).

Journal Article Pediatr Crit Care Med · February 1, 2024 OBJECTIVES: To describe tracheal intubation (TI) practice by Advanced Practice Registered Nurses (APRNs) in North American PICUs, including rates of TI-associated events (TIAEs) from 2015 to 2019. DESIGN/SETTING: Retrospective study using the National Emer ... Full text Link to item Cite

Safety of primary nasotracheal intubation in the pediatric intensive care unit (PICU).

Journal Article Intensive Care Med Paediatr Neonatal · 2024 BACKGROUND: Nasal tracheal intubation (TI) represents a minority of all TI in the pediatric intensive care unit (PICU). The risks and benefits of nasal TI are not well quantified. As such, safety and descriptive data regarding this practice are warranted. ... Full text Open Access Link to item Cite

COVID-19 and Severe Rhabdomyolysis Causing Acute Kidney Injury and Life-Threatening Hyperkalemia in a Pediatric Patient: a Case Report.

Journal Article SN Compr Clin Med · 2023 Though initially believed to primarily be a respiratory pathogen, the SARS-CoV-2 virus has manifested as a virus that has the potential to affect multiple organ systems causing a wide variety of disease and symptomatology. Children have been largely spared ... Full text Open Access Link to item Cite

The Association of Teamwork and Adverse Tracheal Intubation–Associated Events in Advanced Airway Management in the PICU

Journal Article Journal of Pediatric Intensive Care · October 7, 2022 AbstractTracheal intubation (TI) in critically ill children is a life-saving but high-risk procedure that involves multiple team members with diverse clinical skills. We aim to examine the association between the provider-r ... Full text Cite

Intubation practice and outcomes among pediatric emergency departments: A report from National Emergency Airway Registry for Children (NEAR4KIDS).

Journal Article Acad Emerg Med · April 2022 BACKGROUND: Tracheal intubation (TI) practice across pediatric emergency departments (EDs) has not been comprehensively reported. We aim to describe TI practice and outcomes in pediatric EDs in contrast to those in intensive are units (ICUs) and use the da ... Full text Link to item Cite

Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane Oxygenation.

Journal Article Pediatr Crit Care Med · April 1, 2022 OBJECTIVES: Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of t ... Full text Link to item Cite

A narrative review of advanced ventilator modes in the pediatric intensive care unit.

Journal Article Transl Pediatr · October 2021 Respiratory failure is a common reason for pediatric intensive care unit admission. The vast majority of children requiring mechanical ventilation can be supported with conventional mechanical ventilation (CMV) but certain cases with refractory hypoxemia o ... Full text Link to item Cite

Tracheostomy and long-term mechanical ventilation in children after veno-venous extracorporeal membrane oxygenation.

Journal Article Pediatr Pulmonol · September 2021 OBJECTIVE: Our objective is to characterize the incidence of tracheostomy placement and of new requirement for long-term mechanical ventilation after extracorporeal membrane oxygenation (ECMO) among children with acute respiratory failure. We examine wheth ... Full text Link to item Cite

Nutrition in Pediatric Extracorporeal Membrane Oxygenation: A Narrative Review.

Journal Article Front Nutr · 2021 Extracorporeal membrane oxygenation (ECMO) support is increasingly utilized in quaternary pediatric intensive care units. Metabolic derangements and altered nutritional requirements are common in critically ill children supported on ECMO. However, there re ... Full text Open Access Link to item Cite

Acute Kidney Injury, Fluid Overload, and Outcomes in Children Supported With Extracorporeal Membrane Oxygenation for a Respiratory Indication.

Journal Article ASAIO J · March 2020 This study seeks to evaluate the association between acute kidney injury (AKI), fluid overload (FO), and mortality in children supported with extracorporeal membrane oxygenation (ECMO) for refractory respiratory failure. This retrospective observational co ... Full text Link to item Cite

A comprehensive review of the use and understanding of airway pressure release ventilation.

Journal Article Expert Rev Respir Med · March 2020 Introduction: Airway pressure release ventilation (APRV) is a mode of ventilation typically utilized as a rescue or alternative mode for patients with acute respiratory distress syndrome (ARDS) and hypoxemia that is refractory to conventional mechanical ve ... Full text Link to item Cite