Scholars@Duke
Patricia Angellice Martinez Quinones

Patricia Angellice Martinez Quinones

Assistant Professor of Surgery
Trauma, Acute, and Critical Care Surgery

Selected Publications

Association between a 6‐h feeding protocol and postprocedure hospital length of stay following percutaneous endoscopic gastrostomy in hospitalized adults: A before‐and‐after cohort study

Journal Article Journal of Parenteral and Enteral Nutrition · February 2025 AbstractBackgroundTolerance of enteral nutrition following percutaneous endoscopic gastrostomy is a barrier to discharge. This study investigated the impact of an expedited feeding protoco ... Full text Cite

Daily quetiapine after severe TBI improves learning and memory

Journal Article Journal of Trauma and Acute Care Surgery · November 2024 BACKGROUNDTraumatic brain injury (TBI) induces cognitive deficits driven by neuroinflammation and cerebral edema. The commonly used atypical antipsychotic, quetiapine (QTP), has been rece ... Full text Cite

Another brick in the wall

Journal Article Trauma Surgery and Acute Care Open · August 5, 2024 Full text Cite

The impact of hypertonic saline on damage control laparotomy after penetrating abdominal trauma.

Journal Article Eur J Trauma Emerg Surg · June 2024 PURPOSE: The inability to achieve primary fascial closure (PFC) after emergency laparotomy increases the rates of adverse outcomes including fistula formation, incisional hernia, and intraabdominal infection. Hypertonic saline (HTS) infusion improves early ... Full text Link to item Cite

The impact of hypertonic saline on damage control laparotomy after penetrating abdominal trauma

Journal Article EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY · 2024 Full text Cite

Conundrums in the surgical intensive care unit: fevers and antibiotic prophylaxis.

Journal Article Trauma Surg Acute Care Open · 2024 This editorial is in response to the three latest clinical consensus guidelines authored by the Critical Care Committee of the American Association for the Surgery of Trauma. Herein, we discuss their main findings and recommendations and their impact on th ... Full text Link to item Cite

Assessing the Impact of Hands-Free Georgia on Serious Motor Vehicle Accidents

Journal Article The American Surgeon™ · November 2023 Background Hands-Free Georgia Law (HB673) was designed to prevent motor vehicle collisions (MVCs) by banning drivers from using their hands for non-driving-related activities, including cell phone use. We investig ... Full text Cite

Effective use of weight-based enoxaparin for deep vein thrombosis chemoprophylaxis in patients with traumatic brain injury.

Journal Article Am J Surg · January 2022 BACKGROUND: Enoxaparin is the recommended agent for deep vein thrombosis (DVT) chemoprophylaxis in trauma patients. Current literature suggests weight-based dosing is superior to standard dosing for adequate chemoprophylaxis. Literature regarding the use o ... Full text Link to item Cite

Achievement of goal anti‐Xa activity with weight‐based enoxaparin dosing for venous thromboembolism prophylaxis in trauma patients

Journal Article Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy · June 2021 AbstractStudy ObjectiveThe purpose of this study was to evaluate the utility of routine anti‐Xa peak monitoring for trauma patients initiated on weight‐based enoxaparin for venous thromboe ... Full text Cite

Gender Equity at Surgical Conferences: Quantity and Quality

Journal Article Journal of Surgical Research · February 2021 Full text Cite

Invited Commentary: Supporting Surgeon-Scientists: The Future Is Female

Journal Article Journal of the American College of Surgeons · October 2020 Full text Cite

A basic solution to activate the cholinergic anti-inflammatory pathway via the mesothelium?

Journal Article Pharmacol Res · March 2019 Much research now indicates that vagal nerve stimulation results in a systemic reduction in inflammatory cytokine production and an increase in anti-inflammatory cell populations that originates from the spleen. Termed the 'cholinergic anti-inflammatory pa ... Full text Link to item Cite

Hypertension Induced Morphological and Physiological Changes in Cells of the Arterial Wall

Journal Article American Journal of Hypertension · September 11, 2018 AbstractMorphological and physiological changes in the vasculature have been described in the evolution and maintenance of hypertension. Hypertension-induced vascular dysfunction may present itself as a contributing, or con ... Full text Cite

Increase in soluble protein oligomers triggers the innate immune system promoting inflammation and vascular dysfunction in the pathogenesis of sepsis

Journal Article Clinical Science · July 18, 2018 Sepsis is a profoundly morbid and life-threatening condition, and an increasingly alarming burden on modern healthcare economies. Patients with septic shock exhibit persistent hypotension despite adequate volume resuscitation requiring pharmacologi ... Full text Cite

Peritoneal cavity lavage reduces the presence of mitochondrial damage associated molecular patterns in open abdomen patients

Conference Journal of Trauma and Acute Care Surgery · December 2017 BACKGROUNDMitochondrial damage-associated molecular patterns (mtDAMPs), such as mitochondrial DNA and N-formylated peptides, are endogenous molecules released from tissue after traumatic ... Full text Cite

Disparities in Laparoscopic Resection in the Elective Treatment of Diverticulitis

Conference Journal of the American College of Surgeons · October 2017 Full text Cite