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Patrick Shields Calhoun

Professor of Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
Dept of Psychiatry, Box 102505, Durham, NC 27710
Box 3625, Durham, NC 27710

Overview


I specialize in the assessment and treatment of the psychological and behavioral sequelae of posttraumatic stress disorder (PTSD) including the use of cognitive-behavioral interventions to reduce PTSD symptoms, aggression, and substance misuse.

 Research interests

  • The psychological, behavioral, and health consequences of traumatic stress
  • Health services research related to PTSD and associated behavioral difficulties
  • Identification of innovative health behavior change interventions to reduce smoking, alcohol, and drug misuse
  • Implementation Science
  • Psychometric assessment and methodology

Current Duke Appointments & Affiliations


Professor of Psychiatry and Behavioral Sciences · 2026 - Present Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences
Member of the Duke Cancer Institute · 2018 - Present Duke Cancer Institute, Institutes and Centers

Recent Scholarly Works


Assessment and treatment of obsessive compulsive disorder in veterans with PTSD: A qualitative descriptive study.

Journal article Psychol Serv · August 2026 The comorbidity of obsessive compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) is common and leads to worse clinical and psychosocial outcomes than PTSD alone. Yet, OCD remains underdiagnosed and undertreated among veterans, a population w ... Full text Link to item Cite

DNA methylation signatures associated with bipolar disorder in peripheral blood improve prediction models.

Journal article EBioMedicine · June 2026 BACKGROUND: Bipolar disorder (BD) is a major mood disorder influenced by both genetic and environmental factors. While DNA methylation from peripheral tissues can reflect both genetic and environmental influences and reveal insights into disease biology, i ... Full text Link to item Cite

Post-traumatic stress disorder moderates the association between BrainAge acceleration and GrimAge acceleration.

Journal article Neurobiol Aging · May 29, 2026 Individuals with post-traumatic stress disorder (PTSD) are at higher risk for age-related physical comorbidities, such as cardiovascular disorders, and exhibit accelerated epigenetic and brain aging. The present study examined PTSD as a moderator of the as ... Full text Open Access Link to item Cite
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Education


Vanderbilt University · 1998 Ph.D.