Scholars@Duke
Patrick Chung Kay Tam

Patrick Chung Kay Tam

Assistant Professor of Medicine
Medicine, Infectious Diseases

Selected Publications

Cytomegalovirus Infection After CD-34 Selected Autologous Hematopoietic Stem Cell Transplantation for Systemic Sclerosis.

Journal Article Transpl Infect Dis · November 28, 2025 BACKGROUND: Autologous hematopoietic stem cell transplantation (AHSCT) is increasingly used to treat systemic sclerosis (SSc). Data on post-AHSCT infections, including cytomegalovirus (CMV) in this population, are limited. This study aimed to assess risk f ... Full text Link to item Cite

Impact of HeartMate 3 left ventricular assist device infection on outcomes following heart transplant.

Journal Article J Heart Lung Transplant · November 13, 2025 BACKGROUND: Infectious complications are common in patients implanted with HeartMate 3 (HM3) left ventricular assist devices (LVAD). Despite these issues, some patients with LVAD-specific infection are ultimately considered for heart transplant (HT). The i ... Full text Link to item Cite

Hepatitis B Virus NAT Positive Donors in Non-Hepatic Organ Transplant: Quantifying Viral Loads to Optimize Recipient Risk Stratification and Management in the Prevention of Donor-Derived Infection.

Journal Article Clin Transplant · July 2025 Transplantation is one of the few life-saving therapies for patients with end-stage organ disease, yet organ availability remains restrictive. Expanding donors to include those with hepatitis B virus (HBV) infection, incorporating HBV nucleic acid amplific ... Full text Link to item Cite

HOPE in every breath and heartbeat: Understanding transplant eligibility, access barriers, and clinical outcomes in thoracic transplantation in persons with HIV.

Journal Article JHLT Open · May 2025 BACKGROUND: Persons with human immunodeficiency virus (PWH) are living longer, leading to increased end-organ disease from chronic illness. Organ transplantation improves survival in patients with end-organ disease yet remains a constrained resource due to ... Full text Link to item Cite

Limited utility of Epstein-Barr virus (EBV) surveillance for predicting post-transplant lymphoproliferative disorders in adult EBV seropositive lung transplant recipients.

Journal Article J Clin Virol · February 2025 BACKGROUND: EBV DNAemia surveillance, with reduction of immunosuppression at certain viral load (VL) thresholds, is a common practice for mitigating progression from EBV DNAemia to post-transplant lymphoproliferative disorder (PTLD) in lung transplant reci ... Full text Link to item Cite

Epidemiology of Infections in Lung Transplant Recipients Treated With Belatacept.

Journal Article Transpl Infect Dis · 2025 BACKGROUND: Belatacept is a costimulatory blocker that can be used to prevent and treat rejection in lung transplant recipients (LuTRs). The epidemiology of infections in belatacept-treated LuTRs has not been systematically evaluated. METHODS: We performed ... Full text Link to item Cite

Donor-derived Mycoplasma and Ureaplasma infections in lung transplant recipients: A prospective study of donor and recipient respiratory tract screening and recipient outcomes.

Journal Article Am J Transplant · December 2024 Mycoplasma hominis and Ureaplasma species are urogenital mollicutes that can cause serious donor-derived infections in lung transplant recipients. Best practices for mollicute screening remain unknown. We conducted a single-center prospective study analyzi ... Full text Open Access Link to item Cite

Characterizing and Risk Stratifying Musculoskeletal Toxicities after BCMA CAR-T Therapy for Relapsed/Refractory Multiple Myeloma

Conference Blood · November 5, 2024 Introduction: Chimeric antigen receptor-T (CAR-T) cell therapy has revolutionized the treatment landscape in multiple myeloma (MM). Treatment with commercial CAR-T cells targeting B-cell ... Full text Cite

Risk factors, management, and clinical outcomes of invasive Mycoplasma and Ureaplasma infections after lung transplantation.

Journal Article Am J Transplant · April 2024 Mollicute infections, caused by Mycoplasma and Ureaplasma species, are serious complications after lung transplantation; however, understanding of the epidemiology and outcomes of these infections remains limited. We conducted a single-center retrospective ... Full text Open Access Link to item Cite

The diagnostic accuracy of Gram stain on formalin-fixed paraffin-embedded sections of skin tissue in the diagnosis of bacterial skin infection.

Journal Article J Cutan Pathol · March 2024 BACKGROUND AND OBJECTIVE: To evaluate the sensitivity, specificity, and likelihood ratios of Gram stain on formalin-fixed, paraffin-embedded (GS-FFPE) sections of skin in diagnosing bacterial skin infection. METHODS: We reviewed a retrospective series of s ... Full text Link to item Cite

HOPE For a Bright Future

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · 2024 Cite

Infections After Belatacept in Lung Transplant Recipients

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · 2024 Cite

Cryptococcal endophthalmitis complicated by immune reconstitution inflammatory syndrome in a renal transplant recipient: A case report and review of the literature

Journal Article Medical Mycology Case Reports · December 1, 2023 A 59 year old male renal transplant recipient developed endogenous cryptococcal endophthalmitis which was complicated by immune reconstitution inflammatory syndrome (IRIS). Herein we report a novel diagnostic test using lateral flow assay, the management o ... Full text Cite

Pristinamycin-induced sideroblastic anaemia.

Journal Article J Antimicrob Chemother · August 2, 2023 Full text Link to item Cite

Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review.

Journal Article Open Forum Infect Dis · April 2023 Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortal ... Full text Link to item Cite

Detectable Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Human Breast Milk of a Mildly Symptomatic Patient With Coronavirus Disease 2019 (COVID-19).

Journal Article Clin Infect Dis · January 23, 2021 SARS-CoV-2 is a novel coronavirus and causative pathogen to the pandemic illness COVID-19. Although RNA has been detected in various clinical samples, no reports to date have documented SARS-CoV-2 in human milk. This case report describes an actively breas ... Full text Link to item Cite

Intra-abdominal infection with Campylobacter curvus: case report and review of the literature.

Journal Article Access Microbiol · 2021 BACKGROUND: Campylobacter curvus is a Gram-negative bacteria associated with periodontal disease in humans. Cases of extra-oral manifestations of infection are rare with only six reported cases of extra-oral infection including this report that have been i ... Full text Link to item Cite

Investigating the SecY plug movement at the SecYEG translocation channel.

Journal Article EMBO J · October 5, 2005 Protein translocation occurs across the energy-conserving bacterial membrane at the SecYEG channel. The crystal structure of the channel has revealed a possible mechanism for gating and opening. This study evaluates the plug hypothesis using cysteine cross ... Full text Link to item Cite