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Paul Mitaari Magwene

Professor of Biology
Biology
Box 90338, Durham, NC 27708
124 Science Drive, Room 4103 FFSC, Duke Box 90338, Durham, NC 27708

Current Appointments & Affiliations


Professor of Biology · 2022 - Present Biology, Trinity College of Arts & Sciences
Professor in Molecular Genetics and Microbiology · 2022 - Present Molecular Genetics and Microbiology, Basic Science Departments

In the News


Published December 3, 2024
Research & Innovation Seed Grants Total Nearly $2 Million
Published January 30, 2023
Warmer Climate May Drive Fungi to Be More Dangerous to Our Health

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Recent Publications


Genome restructuring and lineage diversification of Cryptococcus neoformans during chronic infection of human hosts.

Journal Article medRxiv · February 21, 2025 Classified as a critical public health threat by the World Health Organization, Cryptococcus neoformans infections with significant morbidity and mortality. Reports of cryptococcosis persistence, relapse, and reinfection date back to the 1950s, yet the fac ... Full text Link to item Cite

Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans.

Journal Article Proc Natl Acad Sci U S A · November 19, 2024 While increased mutation rates typically have negative consequences in multicellular organisms, hypermutation can be advantageous for microbes adapting to the environment. Previously, we identified two hypermutator Cryptococcus neoformans clinical isolates ... Full text Link to item Cite
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Recent Grants


Tri-Institutional Molecular Mycology and Pathogenesis Training Program

Inst. Training Prgm or CMECo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2029

The Genetic Basis of Virulence in Cryptococcus Neoformans

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2017 - 2028

Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

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Education, Training & Certifications


The University of Chicago · 1999 Ph.D.

External Links


Magwene Lab Website