Paul Joseph Mosca | Scholars@Duke

Paul Joseph Mosca
Associate Professor of Surgery

My research focuses on three areas. One is the development of more effective and entirely novel treatments for melanoma. I have a special interest in immunotherapy, novel targeted molecular therapies, and regional chemotherapy for advanced melanoma of the arm or leg. Another area of interest is palliative surgery for cancer with an emphasis on understanding the optimal role and application of this type of surgery in the care of advanced malignancy. A third area of interest is quality and patient safety with an emphasis on communication and work culture.

Current Appointments & Affiliations

Associate Professor of Surgery, Surgical Oncology, Surgery 2011
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2011

Contact Information

10 Bryan Searle Drive, 466G Seeley G. Mudd Bldg, Durham, NC 27710
3966, 10 Bryan Searle Dr, 466G Seeley G Mudd, Durham, NC 27710
paul.mosca@duke.edu (919) 684-6858

Background
Education, Training, & Certifications
- M.B.A., Desales University 2011
- Assistant Professor, Surgery, Lehigh Valley Health Network 2004 - 2010
- Assistant Professor, Surgery, Duke University School of Medicine 2002 - 2004
- Chief Resident, Surgery, Duke University 2001 - 2002
- 2nd Year SAR, Surgery, Duke University 2000 - 2001
- Surgical Research Fellow, Surgery, Duke University 1998 - 2000
- Senior Assistant Resident, Surgery, Duke University 1997 - 1998
- Junior Assistant Resident, Surgery, Duke University 1996 - 1997
- Intern, Surgery, Duke University 1995 - 1996
- M.D., University of Virginia 1995
- Ph.D., University of Virginia 1994
Duke Appointment History
- Instructor, Temporary in the Department of Surgery, Surgical Oncology, Surgery 2011
- Assistant Professor of Surgery, Surgery, Clinical Science Departments 2002 - 2004
- Assistant Research Professor of Surgery, Surgery, Surgical Sciences, Surgery 2001 - 2002
- Instructor, Temporary of Surgery, Surgery, Surgical Sciences, Surgery 2001
Expertise
Subject Headings
Research
Selected Grants
- Improving Melanoma Diagnosis with Pump-Probe Optical Imaging awarded by National Institutes of Health 2013 - 2017
- Dendritic Cell Immunotherapy For Breast Cancer awarded by National Institutes of Health 1998 - 2000
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Puza, C. J., S. A. Myers, A. R. Cardones, G. M. Beasley, and P. J. Mosca. “The impact of transplant rejection on cutaneous squamous cell carcinoma in renal transplant recipients..” Clinical and Experimental Dermatology 44, no. 3 (April 2019): 265–69. https://doi.org/10.1111/ced.13699.
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  - Puza, Charles J., Paul J. Mosca, and Adela R. Cardones. “Early-stage melanoma and hematopoietic stem cell transplantation outcomes..” Journal of the American Academy of Dermatology 80, no. 3 (March 2019): 786–88. https://doi.org/10.1016/j.jaad.2018.07.010.
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  - Kwak, Minyoung, Norma E. Farrow, April K. S. Salama, Paul J. Mosca, Brent A. Hanks, Craig L. Slingluff, and Georgia M. Beasley. “Updates in adjuvant systemic therapy for melanoma..” Journal of Surgical Oncology 119, no. 2 (January 2019): 222–31. https://doi.org/10.1002/jso.25298.
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  - Adair, Kathryn C., Krystina Quow, Allan Frankel, Paul J. Mosca, Jochen Profit, Allison Hadley, Michael Leonard, and J. Bryan Sexton. “The Improvement Readiness scale of the SCORE survey: a metric to assess capacity for quality improvement in healthcare..” Bmc Health Services Research 18, no. 1 (December 17, 2018). https://doi.org/10.1186/s12913-018-3743-0.
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  - Puza, Charles J., Andrew S. Barbas, and Paul J. Mosca. “Outcomes of patients with a pretransplant history of early-stage melanoma..” Melanoma Res 28, no. 5 (October 2018): 471–74. https://doi.org/10.1097/CMR.0000000000000471.
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  - Masoud, Sabran J., Jennifer A. Perone, Norma E. Farrow, Paul J. Mosca, Douglas S. Tyler, and Georgia M. Beasley. “Sentinel Lymph Node Biopsy and Completion Lymph Node Dissection for Melanoma..” Current Treatment Options in Oncology 19, no. 11 (September 19, 2018). https://doi.org/10.1007/s11864-018-0575-4.
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  - Puza, Charles J., Adela R. Cardones, and Paul J. Mosca. “Timing and Number of Cutaneous Squamous Cell Carcinomas in Transplant Recipients..” Jama Dermatology 154, no. 6 (June 2018): 727–28. https://doi.org/10.1001/jamadermatol.2018.0856.
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  - Puza, Charles J., Srirama Josyula, Alicia M. Terando, John H. Howard, Doreen M. Agnese, Paul J. Mosca, Walter T. Lee, and Georgia M. Beasley. “Does the number of sentinel lymph nodes removed affect the false negative rate for head and neck melanoma?.” Journal of Surgical Oncology 117, no. 7 (June 2018): 1584–88. https://doi.org/10.1002/jso.25025.
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  - Puza, Charles J., Adela R. Cardones, and Paul J. Mosca. “Examining the Incidence and Presentation of Melanoma in the Cardiothoracic Transplant Population..” Jama Dermatol 154, no. 5 (May 1, 2018): 589–91. https://doi.org/10.1001/jamadermatol.2018.0130.
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  - Puza, Charles J., Warren S. Warren, and Paul J. Mosca. “Correction to: The changing landscape of dermatology practice: melanoma and pump-probe laser microscopy..” Lasers in Medical Science 32, no. 9 (December 2017). https://doi.org/10.1007/s10103-017-2339-y.
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  - Puza, Charles J., Warren S. Warren, and Paul J. Mosca. “The changing landscape of dermatology practice: melanoma and pump-probe laser microscopy..” Lasers in Medical Science 32, no. 8 (November 2017): 1935–39. https://doi.org/10.1007/s10103-017-2319-2.
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  - Nath, Neel Som, Brian F. Gilmore, Richard K. McCann, and Paul J. Mosca. “Management of a cutaneous squamous cell carcinoma overlying an AV fistula..” Bmj Case Reports 2017 (May 6, 2017). https://doi.org/10.1136/bcr-2016-218932.
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  - Gilmore, Brian F., Adam K. Brys, Neel S. Nath, Michael Barfield, Kristy L. Rialon, Tracy Truong, Gina-Maria Pomann, John Migaly, and Paul J. Mosca. “Clinical Acuity Shorthand System: a standardized classification tool to facilitate handoffs..” The Journal of Surgical Research 211 (May 2017): 163–71. https://doi.org/10.1016/j.jss.2016.10.033.
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  - Mullinax, John E., Hidde M. Kroon, John F. Thompson, Neel Nath, Paul J. Mosca, Jeffrey M. Farma, Rajendra Bhati, et al. “Isolated Limb Infusion as a Limb Salvage Strategy for Locally Advanced Extremity Sarcoma..” Journal of the American College of Surgeons 224, no. 4 (April 2017): 635–42. https://doi.org/10.1016/j.jamcollsurg.2016.12.035.
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  - Kottschade, Lisa, Adam Brys, Tobias Peikert, Mabel Ryder, Laura Raffals, Jerry Brewer, Paul Mosca, Svetomir Markovic, and Svetomir Midwest Melanoma Partnership. “A multidisciplinary approach to toxicity management of modern immune checkpoint inhibitors in cancer therapy..” Melanoma Research 26, no. 5 (October 2016): 469–80. https://doi.org/10.1097/cmr.0000000000000273.
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  - Brys, Adam K., Raghavendra Gowda, Daniel B. Loriaux, Gavin P. Robertson, and Paul J. Mosca. “Nanotechnology-based strategies for combating toxicity and resistance in melanoma therapy..” Biotechnology Advances 34, no. 5 (September 2016): 565–77. https://doi.org/10.1016/j.biotechadv.2016.01.004.
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  - Kim, Jina, Zhifei Sun, Brian C. Gulack, Mohamed A. Adam, Paul J. Mosca, Henry E. Rice, and Elisabeth T. Tracy. “Sentinel lymph node biopsy is a prognostic measure in pediatric melanoma..” Journal of Pediatric Surgery 51, no. 6 (June 2016): 986–90. https://doi.org/10.1016/j.jpedsurg.2016.02.067.
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  - Brys, Adam K., Lubna Bhatti, Mustafa R. Bashir, Tracy A. Jaffe, Georgia M. Beasley, Neel S. Nath, April K. S. Salama, Douglas S. Tyler, and Paul J. Mosca. “Computed Tomography-Based Limb Volume Measurements for Isolated Limb Infusion in Melanoma..” Annals of Surgical Oncology 23, no. 4 (April 2016): 1090–95. https://doi.org/10.1245/s10434-015-4972-7.
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  - Whitley, Melodi Javid, Diana M. Cardona, Alexander L. Lazarides, Ivan Spasojevic, Jorge M. Ferrer, Joan Cahill, Chang-Lung Lee, et al. “A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer..” Science Translational Medicine 8, no. 320 (January 2016). https://doi.org/10.1126/scitranslmed.aad0293.
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  - Robles, Francisco E., Sanghamitra Deb, Jesse W. Wilson, Christina S. Gainey, M Angelica Selim, Paul J. Mosca, Douglas S. Tyler, Martin C. Fischer, and Warren S. Warren. “Pump-probe imaging of pigmented cutaneous melanoma primary lesions gives insight into metastatic potential..” Biomedical Optics Express 6, no. 9 (September 2015): 3631–45. https://doi.org/10.1364/BOE.6.003631.
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  - Brys, Adam K., Michelle M. Schneider, M Angelica Selim, and Paul J. Mosca. “Sentinel lymph node biopsy following a rotational flap..” Bmj Case Reports 2015 (July 14, 2015). https://doi.org/10.1136/bcr-2015-210762.
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  - Jiang, Betty S., Paul J. Speicher, Samantha Thomas, Paul J. Mosca, Amy P. Abernethy, and Douglas S. Tyler. “Quality of life after isolated limb infusion for in-transit melanoma of the extremity..” Ann Surg Oncol 22, no. 5 (May 2015): 1694–1700. https://doi.org/10.1245/s10434-014-3979-9.
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  - Jiang, Xiaoyin, H Bryan Anderson, Cynthia D. Guy, Paul J. Mosca, Richard F. Riedel, and Diana M. Cardona. “Rhabdomyosarcomatous Transformation of a Gastrointestinal Stromal Tumor following Treatment with Imatinib..” Case Reports in Oncological Medicine 2015 (January 28, 2015). https://doi.org/10.1155/2015/317493.
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  - Beasley, G. M., P. Speicher, C. K. Augustine, P. C. Dolber, B. L. Peterson, K. Sharma, P. J. Mosca, et al. “A Multicenter Phase I Dose Escalation Trial to Evaluate Safety and Tolerability of Intra-arterial Temozolomide for Patients with Advanced Extremity Melanoma Using Normothermic Isolated Limb Infusion.” Annals of Surgical Oncology 22, no. 1 (January 1, 2015): 287–94. https://doi.org/10.1245/s10434-014-3887-z.
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  - Kamal, A., N. A. Bhavsar, S. Power, and P. J. Mosca. “Surgical interventions in cancer patients at the end of life: Experiences at an academic medical center..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 32, no. 30_suppl (October 2014).
  - Jiang, Betty S., Georgia M. Beasley, Paul J. Speicher, Paul J. Mosca, Michael A. Morse, Brent Hanks, April Salama, and Douglas S. Tyler. “Immunotherapy following regional chemotherapy treatment of advanced extremity melanoma..” Annals of Surgical Oncology 21, no. 8 (August 2014): 2525–31. https://doi.org/10.1245/s10434-014-3671-0.
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  - Oldan, Jorge D., Olga G. James, Paul J. Mosca, Douglas S. Tyler, and Salvador Borges-Neto. “Two-day lymphoscintigraphic imaging for melanoma..” Nuclear Medicine Communications 35, no. 8 (August 2014): 870–75. https://doi.org/10.1097/mnm.0000000000000136.
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  - Speicher, Paul J., Georgia M. Beasley, Betty Jiang, Michael E. Lidsky, Gregory M. Palmer, Peter M. Scarbrough, Paul J. Mosca, Mark W. Dewhirst, and Douglas S. Tyler. “Hypoxia in melanoma: using optical spectroscopy and EF5 to assess tumor oxygenation before and during regional chemotherapy for melanoma..” Ann Surg Oncol 21, no. 5 (May 2014): 1435–40. https://doi.org/10.1245/s10434-013-3222-0.
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  - Beasley, Georgia M., Paul Speicher, Ketan Sharma, Hilliard Seigler, April Salama, Paul Mosca, and Douglas S. Tyler. “Efficacy of repeat sentinel lymph node biopsy in patients who develop recurrent melanoma..” Journal of the American College of Surgeons 218, no. 4 (April 2014): 686–92. https://doi.org/10.1016/j.jamcollsurg.2013.12.025.
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  - Jiang, B. S., G. M. Beasley, P. J. Speicher, B. Hanks, P. J. Mosca, A. Salama, and D. S. Tyler. “Immunotherapy Following Disease Progression after Regional Treatment of Melanoma.” Journal of Surgical Research 186, no. 2 (February 2014): 682–682. https://doi.org/10.1016/j.jss.2013.11.925.
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  - Speicher, P. J., D. P. Nussbaum, R. R. White, S. Zani, P. J. Mosca, D. G. Blazer, B. M. Clary, T. N. Pappas, D. S. Tyler, and A. Perez. “Defining the Learning Curve for Team-Based Laparoscopic Pancreaticoduodenectomy.” Annals of Surgical Oncology 21, no. 12 (January 1, 2014): 4014–19. https://doi.org/10.1245/s10434-014-3839-7.
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  - Shetty, Gina, Georgia M. Beasley, Sara Sparks, Michael Barfield, Melanie Masoud, Paul J. Mosca, Scott K. Pruitt, et al. “Plasma cytokine analysis in patients with advanced extremity melanoma undergoing isolated limb infusion..” Ann Surg Oncol 20, no. 4 (April 2013): 1128–35. https://doi.org/10.1245/s10434-012-2785-5.
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  - Dannull, J., N. R. Haley, G. Archer, S. Nair, D. Boczkowski, M. Harper, N. D. Rosa, et al. “Melanoma immunotherapy using mature DCs expressing the constitutive proteasome.” Journal of Clinical Investigation 123, no. 7 (2013): 3135–45. https://doi.org/10.1172/JCI67544.
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  - Rialon, K. L., A. P. Abernethy, and P. J. Mosca. “Integration of Palliative Surgery into the Palliative Care Delivery Team.” Journal of Palliative Care & Medicine 02, no. 02 (2013). https://doi.org/10.4172/2165-7386.1000e115.
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  - Beasley, Georgia M., Ketan Sharma, Joyce Wong, Mike Miller, Ryan S. Turley, Michael Lidsky, Melanie Masoud, et al. “A multi-institution experience comparing the clinical and physiologic differences between upper extremity and lower extremity melphalan-based isolated limb infusion..” Cancer 118, no. 24 (December 15, 2012): 6136–43. https://doi.org/10.1002/cncr.27676.
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  - Rialon, K. L., D. G. Blazer, A. P. Abernethy, and P. J. Mosca. “Surgery and the D-Word: Approaching the Topic of Death and Dying with Surgical Patients.” Journal of Palliative Care & Medicine 02, no. 03 (March 1, 2012): 108–108. https://doi.org/10.4172/2165-7386.1000108.
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  - Clawson, Gary A., Eric Kimchi, Susan D. Patrick, Ping Xin, Ramdane Harouaka, Siyang Zheng, Arthur Berg, et al. “Circulating tumor cells in melanoma patients..” Plos One 7, no. 7 (2012). https://doi.org/10.1371/journal.pone.0041052.
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  - Hanna, J., D. G. Blazer, and P. J. Mosca. “Overview of Palliative Surgery: Principles and Priorities.” Journal of Palliative Care & Medicine 02, no. 07 (2012). https://doi.org/10.4172/2165-7386.1000132.
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  - Sharma, K., G. Beasley, R. Turley, A. K. Raymond, G. Broadwater, B. Peterson, P. Mosca, and D. Tyler. “Patterns of recurrence following complete response to regional chemotherapy for in-transit melanoma.” Annals of Surgical Oncology 19, no. 8 (2012): 2563–71. https://doi.org/10.1245/s10434-012-2315-5.
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  - Madhunapantula, SubbaRao V., Paul J. Mosca, and Gavin P. Robertson. “The Akt signaling pathway: an emerging therapeutic target in malignant melanoma..” Cancer Biology & Therapy 12, no. 12 (December 15, 2011): 1032–49. https://doi.org/10.4161/cbt.12.12.18442.
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  - Santillan, Alfredo A., Keith A. Delman, Georgia M. Beasley, Paul J. Mosca, Steven N. Hochwald, Stephen R. Grobmyer, Robert H. Andtbacka, et al. “Predictive factors of regional toxicity and serum creatine phosphokinase levels after isolated limb infusion for melanoma: a multi-institutional analysis..” Annals of Surgical Oncology 16, no. 9 (September 2009): 2570–78. https://doi.org/10.1245/s10434-009-0563-9.
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  - Beasley, Georgia M., Abigail Caudle, Rebecca P. Petersen, Nicole S. McMahon, James Padussis, Paul J. Mosca, Jonathan S. Zager, et al. “A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US..” Journal of the American College of Surgeons 208, no. 5 (May 2009): 706–15. https://doi.org/10.1016/j.jamcollsurg.2008.12.019.
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  - Sharma, Arati, Arun K. Sharma, Subbarao V. Madhunapantula, Dhimant Desai, Sung Jin Huh, Paul Mosca, Shantu Amin, and Gavin P. Robertson. “Targeting Akt3 signaling in malignant melanoma using isoselenocyanates..” Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 15, no. 5 (March 2009): 1674–85. https://doi.org/10.1158/1078-0432.CCR-08-2214.
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  - Padussis, James C., Samuel N. Steerman, Douglas S. Tyler, and Paul J. Mosca. “Pharmacokinetics & drug resistance of melphalan in regional chemotherapy: ILP versus ILI..” International Journal of Hyperthermia : The Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 24, no. 3 (May 2008): 239–49. https://doi.org/10.1080/02656730701816410.
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  - Mosca, Paul J., Erik Teicher, Suresh P. Nair, and Barbara A. Pockaj. “Can surgeons improve survival in stage IV melanoma?.” Journal of Surgical Oncology 97, no. 5 (April 2008): 462–68. https://doi.org/10.1002/jso.20950.
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  - Agostino, Nicole M., Arjumand Ali, Suresh G. Nair, and Paul J. Mosca. “Current immunotherapeutic strategies in malignant melanoma..” Surgical Oncology Clinics of North America 16, no. 4 (October 2007): 945–xi. https://doi.org/10.1016/j.soc.2007.07.010.
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  - Mosca, Paul J., H Kim Lyerly, Timothy M. Clay, and Michael A. Morse. “Dendritic cell vaccines..” Frontiers in Bioscience : A Journal and Virtual Library 12 (January 2007): 4050–60. https://doi.org/10.2741/2371.
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  - Posther, Katherine E., M Angelica Selim, Paul J. Mosca, Wilma E. Stanley, Jeffrey L. Johnson, Douglas S. Tyler, and Hilliard F. Seigler. “Histopathologic characteristics, recurrence patterns, and survival of 129 patients with desmoplastic melanoma..” Annals of Surgical Oncology 13, no. 5 (May 2006): 728–39. https://doi.org/10.1245/aso.2006.03.091.
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  - Aloia, Thomas A., Elizabeth Grubbs, Mark Onaitis, Paul J. Mosca, Tsung-Yen Cheng, Hilliard Seigler, and Douglas S. Tyler. “Predictors of outcome after hyperthermic isolated limb perfusion: role of tumor response..” Archives of Surgery (Chicago, Ill. : 1960) 140, no. 11 (November 2005): 1115–20. https://doi.org/10.1001/archsurg.140.11.1115.
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  - Ho, L. M., P. J. Mosca, and W. M. Thompson. “Pneumatosis intestinalis after lung transplant..” Abdom Imaging 30, no. 5 (September 2005): 598–600. https://doi.org/10.1007/s00261-005-0311-y.
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  - Hall, Jennifer G., Christopher Herman, Jonathan L. Cook, Douglas Tyler, Hilliard F. Seigler, and Paul J. Mosca. “Melanoma arising in a skin graft..” Annals of Plastic Surgery 54, no. 1 (January 2005): 92–96. https://doi.org/10.1097/01.sap.0000136974.62109.01.
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  - Mosca, Paul J., Timothy M. Clay, Michael A. Morse, and H Kim Lyerly. “Immune monitoring..” Cancer Treatment and Research 123 (January 2005): 369–88.
  - Chui, S., T. M. Clay, P. J. Mosca, A. C. Hobeika, T. Osada, L. Galibert, D. Caron, H. K. Lyerly, and M. A. Morse. “Flt3-ligand as a vaccine adjuvant: Results in a study of Flt3-ligand plus tetanus toxoid immunization.” Journal of Applied Research 4, no. 4 (December 1, 2004): 536–49.
  - Morse, M. A., T. M. Clay, A. C. Hobeika, S. Chui, P. J. Mosca, D. Caron, and H. K. Lyerly. “Active immunotherapy with Flt3-ligand mobilized peripheral blood dendritic cells loaded with carcinoembryonic antigen peptide in patients with metastatic malignancies.” Journal of Applied Research 4, no. 4 (December 1, 2004): 554–69.
  - Morse, M. A., H. K. Lyerly, T. M. Clay, O. Abdel-Wahab, S. Y. Chui, J. Garst, J. Gollob, et al. “How does the immune system attack cancer?.” Current Problems in Surgery 41, no. 1 (January 1, 2004): 15–132. https://doi.org/10.1016/j.cpsurg.2003.08.001.
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  - Morse, Michael A., H Kim Lyerly, Timothy M. Clay, Omar Abdel-Wahab, Stephen Y. Chui, Jennifer Garst, Jared Gollob, et al. “Immunotherapy of surgical malignancies..” Current Problems in Surgery 41, no. 1 (January 2004): 15–132. https://doi.org/10.1016/s0011384003001321.
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  - Mosca, Paul J., Douglas S. Tyler, and Hilliard F. Seigler. “Surgical management of cutaneous melanoma: current practice and impact on prognosis..” Advances in Surgery 38 (January 2004): 85–119.
  - Morse, Michael A., Smita K. Nair, Paul J. Mosca, Amy C. Hobeika, Timothy M. Clay, Yuping Deng, David Boczkowski, et al. “Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA..” Cancer Invest 21, no. 3 (June 2003): 341–49.
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  - Mosca, Paul J., Timothy M. Clay, H. Kim Lyerly, and Michael A. Morse. “Current status of dendritic cell immunotherapy of malignancies..” International Reviews of Immunology 22, no. 3–4 (May 2003): 255–81. https://doi.org/10.1080/08830180305223.
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  - Mosca, Paul J., H Kim Lyerly, C Denise Ching, Amy C. Hobeika, Timothy M. Clay, and Michael A. Morse. “Proteomics for monitoring immune responses to cancer vaccines..” Current Opinion in Molecular Therapeutics 5, no. 1 (February 2003): 39–43.
  - Morse, M. A., P. J. Mosca, T. M. Clay, and H. K. Lyerly. “Dendritic cell-based vaccines in cancer: Clinical experience to date.” American Journal of Cancer 1, no. 5 (December 1, 2002): 313–22. https://doi.org/10.2165/00024669-200201050-00002.
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  - Morse, Michael A., Timothy M. Clay, Paul Mosca, and H Kim Lyerly. “Immunoregulatory T cells in cancer immunotherapy..” Expert Opinion on Biological Therapy 2, no. 8 (December 2002): 827–34. https://doi.org/10.1517/14712598.2.8.827.
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  - Mosca, Paul J., Amy C. Hobeika, Kirsten Colling, Timothy M. Clay, Elaine K. Thomas, Dania Caron, H Kim Lyerly, and Michael A. Morse. “Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand..” Journal of Leukocyte Biology 72, no. 3 (September 2002): 546–53.
  - Morse, Michael A., David Rizzieri, Timothy T. Stenzel, Amy C. Hobeika, James J. Vredenburgh, Nelson J. Chao, Timothy M. Clay, Paul J. Mosca, and H Kim Lyerly. “Dendritic cell recovery following nonmyeloablative allogeneic stem cell transplants..” Journal of Hematotherapy & Stem Cell Research 11, no. 4 (August 2002): 659–68. https://doi.org/10.1089/15258160260194802.
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  - Morse, Michael A., Paul J. Mosca, Timothy M. Clay, and H Kim Lyerly. “Dendritic cell maturation in active immunotherapy strategies..” Expert Opinion on Biological Therapy 2, no. 1 (January 2002): 35–43. https://doi.org/10.1517/14712598.2.1.35.
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  - Clay, T. M., A. C. Hobeika, P. J. Mosca, H. K. Lyerly, and M. A. Morse. “Assays for monitoring cellular immune responses to active immunotherapy of cancer..” Clin Cancer Res 7, no. 5 (May 2001): 1127–35.
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  - Mosca, P. J., A. C. Hobeika, T. M. Clay, M. A. Morse, and H. K. Lyerly. “Direct detection of cellular immune responses to cancer vaccines..” Surgery 129, no. 3 (March 2001): 248–54. https://doi.org/10.1067/msy.2001.108609.
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  - Morse, M. A., T. M. Clay, A. C. Hobeika, P. J. Mosca, and H. K. Lyerly. “Monitoring cellular immune responses to cancer immunotherapy..” Current Opinion in Molecular Therapeutics 3, no. 1 (February 2001): 45–52.
  - Hobeika, A. C., T. M. Clay, P. J. Mosca, H. K. Lyerly, and M. A. Morse. “Quantitating therapeutically relevant T-cell responses to cancer vaccines..” Critical Reviews in Immunology 21, no. 1–3 (January 2001): 287–97.
  - Morse, M. A., S. Nair, M. Fernandez-Casal, Y. Deng, M. St Peter, R. Williams, A. Hobeika, et al. “Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 18, no. 23 (December 2000): 3883–93. https://doi.org/10.1200/jco.2000.18.23.3883.
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  - Mosca, P. J., A. C. Hobeika, T. M. Clay, S. K. Nair, E. K. Thomas, M. A. Morse, and H. K. Lyerly. “A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment..” Blood 96, no. 10 (November 2000): 3499–3504.
  - Mosca, P. J., M. A. Morse, T. A. D’Amico, J. Crawford, and H. K. Lyerly. “Gene therapy for lung cancer..” Clinical Lung Cancer 1, no. 3 (February 2000): 218–26. https://doi.org/10.3816/clc.2000.n.005.
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  - Lin, H. B., R. Falchetto, P. J. Mosca, J. Shabanowitz, D. F. Hunt, and J. L. Hamlin. “Mimosine targets serine hydroxymethyltransferase..” J Biol Chem 271, no. 5 (February 2, 1996): 2548–56. https://doi.org/10.1074/jbc.271.5.2548.
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  - Mosca, P. J., H. B. Lin, and J. L. Hamlin. “Mimosine, a novel inhibitor of DNA replication, binds to a 50 kDa protein in Chinese hamster cells..” Nucleic Acids Research 23, no. 2 (January 1995): 261–68. https://doi.org/10.1093/nar/23.2.261.
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  - Hamlin, J. L., P. J. Mosca, and V. V. Levenson. “Defining origins of replication in mammalian cells..” Biochimica Et Biophysica Acta 1198, no. 2–3 (December 1994): 85–111. https://doi.org/10.1016/0304-419x(94)90008-6.
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  - Hamlin, J. L., P. J. Mosca, P. A. Dijkwel, and H. B. Lin. “Initiation of replication at a mammalian chromosomal origin..” Cold Spring Harbor Symposia on Quantitative Biology 58 (January 1993): 467–74. https://doi.org/10.1101/sqb.1993.058.01.053.
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  - Mosca, P. J., P. A. Dijkwel, and J. L. Hamlin. “The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells..” Molecular and Cellular Biology 12, no. 10 (October 1992): 4375–83. https://doi.org/10.1128/mcb.12.10.4375.
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- Book Sections
  - Hobeika, A. C., M. A. Morse, T. M. Clay, T. Osada, P. J. Mosca, and H. K. Lyerly. “Intracellular Cytokine Assays.” In Measuring Immunity: Basic Biology and Clinical Assessment, 336–40, 2005. https://doi.org/10.1016/B978-012455900-4/50290-7.
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  - Speicher, P., D. S. Tyler, and paul Mosca. “Management of In-transit Malignant Melanoma.” In Melanoma From Early Detection to Treatment, n.d.
- Other Articles
  - Mosca, Paul J., Dan G. Blazer, Jane L. Wheeler, and Amy P. Abernethy. “When a chance to cut is not a chance to cure: a future for palliative surgery?.” Annals of Surgical Oncology, November 2011. https://doi.org/10.1245/s10434-011-1787-z.
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  - Mosca, Paul J., and Gavin P. Robertson. “Augmentation of tumor-specific immunity by upregulation of apoptotic melanoma cell calreticulin expression..” Cancer Biol Ther, March 15, 2011.
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  - Madhunapantula, SubbaRao V., Paul Mosca, and Gavin P. Robertson. “Steroid hormones drive cancer development..” Cancer Biol Ther, October 15, 2010.
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  - Morse, M. A., T. M. Clay, A. C. Hobeika, P. J. Mosca, and H. K. Lyerly. “Surrogate markers of response to cancer immunotherapy..” Expert Opinion on Biological Therapy, March 2001. https://doi.org/10.1517/14712598.1.2.153.
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  - Mosca, P. J., G. E. Loyd, and K. Tsueda. “Effects of ThermH2Osorb carbon dioxide absorber on temperature and humidity in the anesthetic circuit..” Anesthesia and Analgesia, May 1997. https://doi.org/10.1097/00000539-199705000-00044.
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  - Mosca, P. J., P. A. Dijkwel, and J. L. Hamlin. “Erratum: The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells (Mol. Cell. Biol., Vol. 12, No. 10, p. 4375, (1992)).” Molecular and Cellular Biology, January 1, 1993.
- Conference Papers
  - Miura, John T., Hidde M. Kroon, Georgia M. Beasley, Dean Mullen, Norma E. Farrow, Paul J. Mosca, Michael C. Lowe, et al. “Long-Term Oncologic Outcomes After Isolated Limb Infusion for Locoregionally Metastatic Melanoma: An International Multicenter Analysis..” In Annals of Surgical Oncology, 2019. https://doi.org/10.1245/s10434-019-07288-w.
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  - Masoud, S. J., J. B. Hu, G. Beasley, J. H. Stewart, and P. J. Mosca. “Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size.” In Annals of Surgical Oncology, 26:S42–S42. SPRINGER, 2019.
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  - Puza, Charles J., and Paul J. Mosca. “Examining the incidence and presentation of melanoma in thoracic transplant patients.” In Journal of the American Academy of Dermatology, 79:AB138–AB138. MOSBY-ELSEVIER, 2018.
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  - Puza, Charles J., and Paul J. Mosca. “Incidence and presentation of squamous cell carcinoma in renal transplant patients after rejection episodes.” In Journal of the American Academy of Dermatology, 79:AB165–AB165. MOSBY-ELSEVIER, 2018.
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  - Puza, C. J., S. A. Myers, A. R. Cardones, G. M. Beasley, and P. J. Mosca. “The effect of rejection episodes on squamous cell carcinoma (SCC) in transplant patients.” In Journal of Investigative Dermatology, 138:S50–S50. ELSEVIER SCIENCE INC, 2018.
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  - Puza, C. J., S. Josyula, D. M. Agnese, J. Howard, A. M. Terando, P. J. Mosca, W. T. Lee, and G. Beasley. “Is the Number of Sentinel Lymph Nodes Important for Head and Neck Melanoma Staging?.” In Annals of Surgical Oncology, 25:S172–S172. SPRINGER, 2018.
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  - Whitley, Melodi J., Diana M. Cardona, Dan G. Blazer, Shelley Hwang, Rachel A. Greenup, Paul J. Mosca, Joan Cahill, et al. “Abstract SY36-03: Intraoperative molecular imaging with protease-activated fluorescent imaging agents.” In Cancer Research, Vol. 75. American Association for Cancer Research (AACR), 2015. https://doi.org/10.1158/1538-7445.am2015-sy36-03.
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  - Whitley, M. J., D. M. Cardona, D. G. Blazer, E. Hwang, R. A. Greenup, P. J. Mosca, J. Cahill, et al. “A Phase I Clinical Trial of LUM015: A Protease-activated Fluorescent Imaging Agent to Detect Cancer during Surgery.” In Annals of Surgical Oncology, 22:S11–12. SPRINGER, 2015.
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  - Beasley, Georgia M., Paul Speicher, Christina K. Augustine, Paul C. Dolber, Bercedis L. Peterson, Ketan Sharma, Paul J. Mosca, et al. “A multicenter phase I dose escalation trial to evaluate safety and tolerability of intra-arterial temozolomide for patients with advanced extremity melanoma using normothermic isolated limb infusion..” In Annals of Surgical Oncology, 22:287–94, 2015. https://doi.org/10.1245/s10434-014-3887-z.
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  - Speicher, Paul J., Daniel P. Nussbaum, Rebekah R. White, Sabino Zani, Paul J. Mosca, Dan G. Blazer, Bryan M. Clary, Theodore N. Pappas, Douglas S. Tyler, and Alexander Perez. “Defining the learning curve for team-based laparoscopic pancreaticoduodenectomy..” In Ann Surg Oncol, 21:4014–19, 2014. https://doi.org/10.1245/s10434-014-3839-7.
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  - Whitley, Melodi Javid, Diana M. Cardona, Dan G. Blazer, Shelley E. Hwang, Paul J. Mosca, Joan Cahill, Jorge M. Ferrer, et al. “A phase I study of the safety and activation of a cathepsin-activatable fluorescent cancer-specific probe LUM015..” In Journal of Clinical Oncology, 32:TPS11135–TPS11135. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.tps11135.
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  - Posther, K. E., P. J. Mosca, M. A. Selim, W. E. Stanley, J. L. Johnson, D. S. Tyler, and H. F. Seigler. “Histopathologic characteristics, recurrence patterns, and survival of 129 patients with desmoplastic melanoma.” In Annals of Surgical Oncology, 11:S78–S78. Springer Nature, 2004. https://doi.org/10.1007/bf02524057.
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  - Colling, K. L., A. C. Hobeika, P. J. Mosca, T. M. Clay, H. K. Lyerly, and M. A. Morse. “Enumerating functionally mature monocyte-derived dendritic cells for use in cancer immunotherapy..” In Blood, 98:851A-851A. AMER SOC HEMATOLOGY, 2001.
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  - Hobeika, A. C., S. Peplinski, M. A. Morse, P. J. Mosca, T. C. Clay, and H. K. Lyerly. “Quantitating antigen specific T cell responses in peripheral blood: A comparison of peptide MHC tetramer, ELISpot and intracellular cytokine analysis..” In Blood, 98:23A-23A. AMER SOC HEMATOLOGY, 2001.
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  - Mosca, P. J., A. C. Hobeika, T. M. Clay, S. K. Nair, E. K. Thomas, D. A. Caron, H. K. Lyerly, and M. A. Morse. “Multiple signals are required for IL-12 production by Flt-3 ligand mobilized dendritic cells..” In Blood, 96:295A-295A. AMER SOC HEMATOLOGY, 2000.
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  - MOSCA, P. J., P. A. DIJKWEL, and J. L. HAMLIN. “THE PLANT AMINO-ACID MIMOSINE MAY INHIBIT INITIATION AT ORIGINS OF REPLICATION IN CHINESE-HAMSTER CELLS (MOLECULAR AND CELLULAR BIOLOGY, VOL 12, PG 4375, 1992).” In Molecular and Cellular Biology, 13:1981–1981. AMER SOC MICROBIOLOGY, 1993.
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