Current Appointments & Affiliations
Associate Professor of Biomedical Engineering
·
2025 - Present
Biomedical Engineering,
Pratt School of Engineering
Recent Publications
Functional alignment of protein language models via reinforcement learning
Preprint · May 8, 2025 Full text CiteScalable and cost-efficient custom gene library assembly from oligopools
Preprint · March 22, 2025 Full text CiteDroplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity.
Journal Article Journal of biological engineering · February 2025 BackgroundAngiotensin-Converting Enzyme 2 (ACE2) is a crucial peptidase in human peptide hormone signaling, catalyzing the conversion of Angiotensin-II to Angiotensin-(1-7), which activates the Mas receptor and elicits vasodilation, increased bloo ... Full text CiteRecent Grants
Application of Machine Learning to Design of Catalysts with Improved Properties and Development of AI Model to Generate Protein Sequences with Tailored Properties
ResearchPrincipal Investigator · Awarded by Boehringer Ingelheim Pharmaceuticals, Inc. · 2024 - 2028Structure-Guided Protein Recombination to Develop Single Species Elimination Bacteriophage Endolysins for Microbiome Modulation
ResearchPrincipal Investigator · Awarded by Army Research Office · 2024 - 2027Collaborative Research: MFB: Integrating deep learning and high-throughput experimentation to rapidly navigate protein fitness landscapes for non-native enzyme catalysis
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2025 - 2026View All Grants
Education, Training & Certifications
California Institute of Technology ·
2012
Ph.D.