Current Duke Appointments & Affiliations
Associate Professor of Biomedical Engineering
·
2025 - Present
Biomedical Engineering,
Pratt School of Engineering
Recent Scholarly Works
Benchmarking and behavioral characterization of LLM agents for protein design.
Preprint · May 8, 2026 Large language models (LLMs) are increasingly deployed as agents for scientific discovery, but standardized frame-works for evaluating their performance and behaviour in scientific workflows are lacking. Protein design provides a demanding test case becaus ... Full text Link to item CiteScalable and cost-efficient custom gene library assembly from oligopools.
Journal article Science advances · May 2026 Advances in metagenomics, deep learning, and generative protein design have enabled broad in silico exploration of sequence space, but experimental characterization is still constrained by the cost and scalability of DNA synthesis. Here, we present OMEGA ( ... Full text CiteAlphaFast: High-throughput AlphaFold 3 via GPU-accelerated MSA construction.
Preprint · February 18, 2026 Full text Link to item CiteRecent Grants
Application of Machine Learning to Design of Catalysts with Improved Properties and Development of AI Model to Generate Protein Sequences with Tailored Properties
ResearchPrincipal Investigator · Awarded by Boehringer Ingelheim Pharmaceuticals, Inc. · 2024 - 2028Structure-Guided Protein Recombination to Develop Single Species Elimination Bacteriophage Endolysins for Microbiome Modulation
ResearchPrincipal Investigator · Awarded by Army Research Office · 2024 - 2027Self-driving laboratories for autonomous exploration of protein sequence space
ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2024 - 2027View All Grants
Education
California Institute of Technology ·
2012
Ph.D.