Scholars@Duke
Prachi T. Parikh

Prachi T. Parikh

Assistant Professor of Neurology
Neurology, Epilepsy and Sleep

Selected Publications

Responsive neurostimulation detections: "Recognizing the unseen".

Journal Article Epileptic Disord · October 2025 BACKGROUND: Closed-loop responsive neurostimulation (RNS) is an established non-resective neuromodulatory therapy for individuals with drug-resistant epilepsy (DRE). RNS systems are typically programmed to detect and respond to predefined seizure onset pat ... Full text Open Access Link to item Cite

Visual Features in Stereo-Electroencephalography to Predict Surgical Outcome: A Multicenter Study.

Journal Article Ann Neurol · September 2025 OBJECTIVE: Epilepsy surgery needs predictive features that are easily implemented in clinical practice. Previous studies are limited by small sample sizes, lack of external validation, and complex computational approaches. We aimed to identify and validate ... Full text Open Access Link to item Cite

The association of seizure control with neuropathology in dementia.

Journal Article Brain · July 7, 2025 Seizures in people with dementia (PWD) are associated with faster cognitive decline and worse clinical outcomes. However, the relationship between ongoing seizure activity and post-mortem neuropathology in PWD remains unexplored. We compared post-mortem fi ... Full text Open Access Link to item Cite

Sleep-related hypermotor seizures originating from the occipital lobe.

Journal Article Epileptic Disord · December 2024 We present two unique cases of sleep-related hypermotor epilepsy (SHE) originating from the occipital lobe. Patients with sleep-related seizures and drug-resistant occipital lobe epilepsy were identified from the ANPHY lab stereo-electroencephalography (SE ... Full text Link to item Cite

Source Localization of Normal Variants Seen on EEG.

Journal Article J Clin Neurophysiol · February 1, 2024 PURPOSE: The EEG is an essential neurological diagnostic tool. EEG abnormalities can guide diagnosis and management of epilepsy. There are also distinctive EEG waveforms that are seen in healthy individuals. It is critical not to misinterpret these as abno ... Full text Link to item Cite

Prognostic value of the 5-SENSE Score to predict focality of the seizure-onset zone as assessed by stereoelectroencephalography: a prospective international multicentre validation study.

Journal Article BMJ Neurol Open · 2024 INTRODUCTION: Epilepsy surgery is the only curative treatment for patients with drug-resistant focal epilepsy. Stereoelectroencephalography (SEEG) is the gold standard to delineate the seizure-onset zone (SOZ). However, up to 40% of patients are subsequent ... Full text Open Access Link to item Cite