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Pranam D. Chatterjee

Assistant Professor of Biomedical Engineering
Biomedical Engineering
101 Science Drive, CIEMAS 2353A, Durham, NC 27705

Current Appointments & Affiliations


Assistant Professor of Biomedical Engineering · 2022 - Present Biomedical Engineering, Pratt School of Engineering
Assistant Professor of Computer Science · 2023 - Present Computer Science, Trinity College of Arts & Sciences
Assistant Professor in Biostatistics & Bioinformatics · 2023 - Present Biostatistics & Bioinformatics, Division of Integrative Genomics, Biostatistics & Bioinformatics
Member of the Duke Cancer Institute · 2024 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published September 15, 2023
Duke Companies and Faculty Share Ideas with Investors at Triangle Venture Day

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Recent Publications


PTM-Mamba: a PTM-aware protein language model with bidirectional gated Mamba blocks.

Journal Article Nature methods · May 2025 Current protein language models (LMs) accurately encode protein properties but have yet to represent post-translational modifications (PTMs), which are crucial for proteomic diversity and influence protein structure, function and interactions. To address t ... Full text Cite

Programmable protein stabilization with language model-derived peptide guides.

Journal Article Nature communications · April 2025 Dysregulated protein degradation via the ubiquitin-proteasomal pathway can induce numerous disease phenotypes, including cancer, neurodegeneration, and diabetes. While small molecule-based targeted protein degradation (TPD) and targeted protein stabilizati ... Full text Cite
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Recent Grants


Generative Design of Programmable Therapeutics

ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2024 - 2029

Medical Scientist Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

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Education, Training & Certifications


Massachusetts Institute of Technology · 2020 Ph.D.

External Links


programmable.bio