Current Appointments & Affiliations
Professor in Surgery
·
2024 - Present
Surgery, Surgical Sciences,
Surgery
Associate Professor of Biochemistry
·
2021 - Present
Biochemistry,
Basic Science Departments
Member of the Duke Human Vaccine Institute
·
2018 - Present
Duke Human Vaccine Institute,
Institutes and Centers
Member of the Duke Cancer Institute
·
2025 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Journal Article Cell · November 13, 2025 Full text Link to item CiteAcquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Journal Article Structure · August 7, 2025 Although most broadly neutralizing antibodies (bNAbs) specific for the CD4-binding site (CD4-BS) of HIV-1 interact with a single gp120 protomer, a few mimic the quaternary binding mode of CD4, making contact with a second protomer through elongated heavy c ... Full text Link to item CiteDesign of SARS-CoV-2 RBD immunogens to focus immune responses toward conserved coronavirus epitopes.
Journal Article J Virol · July 22, 2025 SARS-CoV-2 continues to evolve, with new variants emerging that evade pre-existing immunity and limit the efficacy of existing vaccines. One approach toward developing superior, variant-proof vaccines is to engineer immunogens that preferentially elicit an ... Full text Link to item CiteRecent Grants
Interdisciplinary Research Training Program in AIDS
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2010 - 2030Structural definition of CD4-induced HIV-1 Env conformational changes required for infection
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2030Duke Center for HIV Structural Biology
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027View All Grants
Education, Training & Certifications
Centre for Cellular and Molecular Biology (India) ·
2003
Ph.D.
Jadavpur University (India) ·
1996
M.S.
Jadavpur University (India) ·
1994
B.S.