Overview
My research interests include intensity-modulated radiation therapy (IMRT), volumetric-modulated arc therapy (VMAT), Dynamic Electron Arc Radiotherapy (DEAR), and image-guided radiation therapy (IGRT). For IMRT, my work includes the development of the research platform, fast and accurate dose calculations, optimization based on physical and biological objectives such as generalized equivalent uniform dose (gEUD), and delivery with a dynamic multi-leaf collimator (DMLC). For VMAT, I am interested in optimization, quality assurance, and novel applications. For DEAR, I'm interested in the treatment planning and delivery verifications. For IGRT, my work includes the development of the infrastructure of the online and offline image guidance, characterization of patient anatomic changes and treatment uncertainties, margin calculations, and adaptive treatment planning. My recent research interests also include the use of AI in treatment planning, Brachytherapy dose calculation and plan optimization.
My clinical interests include prostate cancer, head and neck cancer, total body irradiation (TBI), and total skin irradiation (TSI)
My clinical interests include prostate cancer, head and neck cancer, total body irradiation (TBI), and total skin irradiation (TSI)
Current Appointments & Affiliations
Professor of Radiation Oncology
·
2021 - Present
Radiation Oncology,
Clinical Science Departments
Recent Publications
Developing and validating a bi-polar gated respiratory motion management strategy for improved lung stereotactic body radiotherapy treatment.
Journal Article Cancer Pathog Ther · September 2025 BACKGROUND: Stereotactic body radiotherapy (SBRT) is an effective treatment for early-stage non-small cell lung cancer. However, patient breathing can affect treatment accuracy. Therefore, this study aimed to develop a bi-polar (BP) gated motion management ... Full text Link to item CiteMonte Carlo investigation of dosimetry in shielded region in total body irradiation treatment.
Journal Article Biomed Phys Eng Express · August 5, 2025 Purpose. Total body irradiation (TBI) is commonly used to treat hematological diseases requiring bone marrow transplantation. Partial transmission blocks (PTB) are utilized to shield critical organs such as the lungs and kidneys. Previous phantom measureme ... Full text Link to item CiteA technique for achieving arbitrary machine dose rates via MLC leaf motion modulation using fixed-gantry IMRT delivery mode.
Journal Article Med Phys · June 2025 BACKGROUND: The medical linear accelerator (Linac) typically operates at a constant but discrete dose rate for both 3D conformal fields and intensity modulation radiotherapy (IMRT) fields. However, in certain clinical and radiobiological scenarios, such as ... Full text Link to item CiteRecent Grants
Knowledge-based Tutoring for Knowledge-based Radiation Therapy
ResearchCo Investigator · Awarded by Varian Medical Systems, Inc. · 2020 - 2022Cross-disciplinary Training in Medical Physics
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2007 - 2013Image-Guide Radiation Therapy of Prostate Cancer
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2011View All Grants
Education, Training & Certifications
Columbia University ·
1994
Ph.D.