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Qiuwen Wu

Professor of Radiation Oncology
Radiation Oncology
Box 3295 Med Ctr, Durham, NC 27710
00568 Duke South White Zone, Durham, NC 27710

Overview


My research interests include intensity-modulated radiation therapy (IMRT), volumetric-modulated arc therapy (VMAT), Dynamic Electron Arc Radiotherapy (DEAR), and image-guided radiation therapy (IGRT). For IMRT, my work includes the development of the research platform, fast and accurate dose calculations, optimization based on physical and biological objectives such as generalized equivalent uniform dose (gEUD), and delivery with a dynamic multi-leaf collimator (DMLC). For VMAT, I am interested in optimization, quality assurance, and novel applications. For DEAR, I'm interested in the treatment planning and delivery verifications. For IGRT, my work includes the development of the infrastructure of the online and offline image guidance, characterization of patient anatomic changes and treatment uncertainties, margin calculations, and adaptive treatment planning. My recent research interests also include the use of AI in treatment planning, Brachytherapy dose calculation and plan optimization.

My clinical interests include prostate cancer, head and neck cancer, total body irradiation (TBI), and total skin irradiation (TSI)

Current Appointments & Affiliations


Professor of Radiation Oncology · 2021 - Present Radiation Oncology, Clinical Science Departments

Recent Publications


Developing and validating a bi-polar gated respiratory motion management strategy for improved lung stereotactic body radiotherapy treatment.

Journal Article Cancer Pathog Ther · September 2025 BACKGROUND: Stereotactic body radiotherapy (SBRT) is an effective treatment for early-stage non-small cell lung cancer. However, patient breathing can affect treatment accuracy. Therefore, this study aimed to develop a bi-polar (BP) gated motion management ... Full text Link to item Cite

Monte Carlo investigation of dosimetry in shielded region in total body irradiation treatment.

Journal Article Biomed Phys Eng Express · August 5, 2025 Purpose. Total body irradiation (TBI) is commonly used to treat hematological diseases requiring bone marrow transplantation. Partial transmission blocks (PTB) are utilized to shield critical organs such as the lungs and kidneys. Previous phantom measureme ... Full text Link to item Cite

A technique for achieving arbitrary machine dose rates via MLC leaf motion modulation using fixed-gantry IMRT delivery mode.

Journal Article Med Phys · June 2025 BACKGROUND: The medical linear accelerator (Linac) typically operates at a constant but discrete dose rate for both 3D conformal fields and intensity modulation radiotherapy (IMRT) fields. However, in certain clinical and radiobiological scenarios, such as ... Full text Link to item Cite
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Recent Grants


Knowledge-based Tutoring for Knowledge-based Radiation Therapy

ResearchCo Investigator · Awarded by Varian Medical Systems, Inc. · 2020 - 2022

Cross-disciplinary Training in Medical Physics

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2007 - 2013

Image-Guide Radiation Therapy of Prostate Cancer

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2011

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Education, Training & Certifications


Columbia University · 1994 Ph.D.