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Rishi Kamaleswaran

Associate Professor in Surgery
Trauma, Acute, and Critical Care Surgery

Overview


My research focuses on the application of artificial intelligence, machine learning, and data analytics in healthcare, particularly in critical care and perioperative medicine; and cystic fibrosis. I have published numerous papers on the development of predictive models for sepsis, acute respiratory distress syndrome, and other critical conditions. My work utilizes large datasets, electronic health records, and physiological waveform analysis to improve patient outcomes. I have also explored the use of deep learning techniques for disease diagnosis and prediction, including the detection of cardiac arrhythmias and Parkinson's disease. Additionally, my research has investigated the potential of wearable sensors and remote patient monitoring to enhance healthcare delivery. Through collaborations with clinicians and researchers, I have validated and translated my models into clinical practice. Overall, my goal is to leverage data-driven approaches to transform healthcare and improve patient care.

Current Appointments & Affiliations


Associate Professor in Surgery · 2024 - Present Trauma, Acute, and Critical Care Surgery, Surgery
Associate Professor in Anesthesiology · 2024 - Present Anesthesiology, Critical Care Medicine, Anesthesiology
Associate Professor of Biostatistics & Bioinformatics · 2024 - Present Biostatistics & Bioinformatics, Division of Translational Biomedical, Biostatistics & Bioinformatics
Associate Professor of Biomedical Engineering · 2024 - Present Biomedical Engineering, Pratt School of Engineering
Associate Professor in the Department of Electrical and Computer Engineering · 2024 - Present Electrical and Computer Engineering, Pratt School of Engineering

In the News


Published January 30, 2025
AI-powered prediction model enhances blood transfusion decision-making in ICU patients
Published January 30, 2025
AI model predicts blood transfusion needs in ICU patients
Published October 3, 2024
Sepsis-Induced ARF Phenotypes Show Special Organ Injury Characteristics & Clinical Outcomes Differences

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Recent Publications


Improving clinical decision support through interpretable machine learning and error handling in electronic health records.

Journal Article J Am Med Inform Assoc · January 1, 2026 OBJECTIVE: To develop an electronic medical record (EMR) data processing tool that confers clinical context to machine learning (ML) algorithms for error handling, bias mitigation, and interpretability. MATERIALS AND METHODS: We present Trust-MAPS, an algo ... Full text Link to item Cite

CXR-TFT: Multi-modal Temporal Fusion Transformer for Predicting Chest X-Ray Trajectories

Conference Lecture Notes in Computer Science · January 1, 2026 In intensive care units (ICUs), patients with complex clinical conditions require vigilant monitoring and prompt interventions. Chest X-rays (CXRs) are a vital diagnostic tool, providing insights into clinical trajectories, but their irregular acquisition ... Full text Cite

Benchmarking Foundation Models with Multimodal Public Electronic Health Records.

Journal Article IEEE J Biomed Health Inform · December 16, 2025 Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the performance, fairn ... Full text Link to item Cite
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Recent Grants


1/3 CTSA UM1 at Duke University

ResearchCore Co-Lead · Awarded by National Institutes of Health · 2025 - 2032

NCATS N3C Cancer Enclave

ResearchPrincipal Investigator · Awarded by Axle Informatics · 2025 - 2029

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Education, Training & Certifications


University of Ontario Institute of Technology (Canada) · 2016 Ph.D.
University of Ontario Institute of Technology (Canada) · 2011 M.S.
University of Ontario Institute of Technology (Canada) · 2009 B.H.S.

External Links


Kamaleswaran Lab