Scholars@Duke

• Research
• 

  Selected Grants

  • Molecular elucidation of the Francisella tularensis virulence mechanism awarded by National Institutes of Health 2021 - 2026
  • Deciphering fundamental biological processes involving protein-nucleic acid interactions at the molecular level awarded by National Institutes of Health 2019 - 2023
  • A role for pathogen-induced IL-10 production in susceptibility to MS awarded by National Multiple Sclerosis Society 2014 - 2015
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Afek, Ariel, Honglue Shi, Atul Rangadurai, Harshit Sahay, Alon Senitzki, Suela Xhani, Mimi Fang, et al. “DNA mismatches reveal conformational penalties in protein-DNA recognition.” Nature 587, no. 7833 (November 2020): 291–96. https://doi.org/10.1038/s41586-020-2843-2.
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    • Saleem, Ali F., Ahreen Allana, Lauren Hale, Alondra Diaz, Raul Salinas, Cristina Salinas, Shahida M. Qureshi, et al. “The Gut of Healthy Infants in the Community as a Reservoir of ESBL and Carbapenemase-Producing Bacteria.” Antibiotics (Basel, Switzerland) 9, no. 6 (May 27, 2020): E286. https://doi.org/10.3390/antibiotics9060286.
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    • Stelling, Allison L., Amy Y. Liu, Wenjie Zeng, Raul Salinas, Maria A. Schumacher, and Hashim M. Al-Hashimi. “Infrared Spectroscopic Observation of a G-C+ Hoogsteen Base Pair in the DNA:TATA-Box Binding Protein Complex Under Solution Conditions.” Angew Chem Int Ed Engl 58, no. 35 (August 26, 2019): 12010–13. https://doi.org/10.1002/anie.201902693.
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    • Wang, Liuyang, Kelly J. Pittman, Jeffrey R. Barker, Raul E. Salinas, Ian B. Stanaway, Graham D. Williams, Robert J. Carroll, et al. “An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease.” Cell Host Microbe 24, no. 2 (August 8, 2018): 308-323.e6. https://doi.org/10.1016/j.chom.2018.07.007.
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    • Wang, Liuyang, Emily R. Ko, James J. Gilchrist, Kelly J. Pittman, Anna Rautanen, Matti Pirinen, J Will Thompson, et al. “Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis.” Sci Adv 3, no. 3 (March 2017): e1602096. https://doi.org/10.1126/sciadv.1602096.
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    • Salinas, Raul E., Cassandra Ogohara, Monica I. Thomas, Kajal P. Shukla, Samuel I. Miller, and Dennis C. Ko. “A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death.” Mol Biol Cell 25, no. 1 (January 2014): 76–86. https://doi.org/10.1091/mbc.E13-06-0294.
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    • Homa, Nicholas J., Raul Salinas, Eleonora Forte, Timothy J. Robinson, Mariano A. Garcia-Blanco, and Micah A. Luftig. “Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency.” J Virol 87, no. 22 (November 2013): 12291–301. https://doi.org/10.1128/JVI.02464-13.
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    • Price, Alexander M., Jason P. Tourigny, Eleonora Forte, Raul E. Salinas, Sandeep S. Dave, and Micah A. Luftig. “Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation.” J Virol 86, no. 20 (October 2012): 11096–106. https://doi.org/10.1128/JVI.01069-12.
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    • Robinson, Timothy J., Eleonora Forte, Raul E. Salinas, Shaan Puri, Matthew Marengo, Mariano A. Garcia-Blanco, and Micah A. Luftig. “SplicerEX: a tool for the automated detection and classification of mRNA changes from conventional and splice-sensitive microarray expression data.” Rna 18, no. 8 (August 2012): 1435–45. https://doi.org/10.1261/rna.033621.112.
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    • Forte, Eleonora, Raul E. Salinas, Christina Chang, Ting Zhou, Sarah D. Linnstaedt, Eva Gottwein, Cassandra Jacobs, et al. “The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells.” J Virol 86, no. 12 (June 2012): 6889–98. https://doi.org/10.1128/JVI.07056-11.
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    • Salinas-Mondragon, Raul E., Jyoti D. Kajla, Imara Y. Perera, Christopher S. Brown, and Heike Winter Sederoff. “Role of inositol 1,4,5-triphosphate signalling in gravitropic and phototropic gene expression.” Plant, Cell & Environment 33, no. 12 (December 2010): 2041–55. https://doi.org/10.1111/j.1365-3040.2010.02204.x.
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    • Jacquet, Benoit V., Raul Salinas-Mondragon, Huixuan Liang, Blair Therit, Justin D. Buie, Michael Dykstra, Kenneth Campbell, Lawrence E. Ostrowski, Steven L. Brody, and H Troy Ghashghaei. “FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain.” Development (Cambridge, England) 136, no. 23 (December 2009): 4021–31. https://doi.org/10.1242/dev.041129.
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    • Jacquet, B. V., M. Patel, M. Iyengar, H. Liang, B. Therit, R. Salinas-Mondragon, C. Lai, J. C. Olsen, E. S. Anton, and H. T. Ghashghaei. “Analysis of neuronal proliferation, migration and differentiation in the postnatal brain using equine infectious anemia virus-based lentiviral vectors.” Gene Therapy 16, no. 8 (August 2009): 1021–33. https://doi.org/10.1038/gt.2009.58.
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    • Kimbrough, Jeffery M., Raul Salinas-Mondragon, Wendy F. Boss, Christopher S. Brown, and Heike Winter Sederoff. “The fast and transient transcriptional network of gravity and mechanical stimulation in the Arabidopsis root apex.” Plant Physiology 136, no. 1 (September 3, 2004): 2790–2805. https://doi.org/10.1104/pp.104.044594.
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    • Salinas-Mondragón, Raúl E., Cristina Garcidueñas-Piña, and Plinio Guzmán. “Early elicitor induction in members of a novel multigene family coding for highly related RING-H2 proteins in Arabidopsis thaliana.” Plant Molecular Biology 40, no. 4 (1999): 579–90. https://doi.org/10.1023/a:1006267201855.
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    • Salinas, Raul. “Regulation of transcription in roots of Arabidopsis gravity mutant,” n.d.
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  • Other Articles

    • Salinas, Raul. “Gravity and Light: Integrating Transcriptional Regulation in Roots,” n.d.
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  • Digital Publications

    • Salinas, Raul, and Maria Schumacher. “ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD.” Genes and Developments, n.d.

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