Current Appointments & Affiliations
Associate Professor of Medicine
·
2021 - Present
Medicine, Cardiology,
Medicine
Associate Professor of Pathology
·
2021 - Present
Pathology,
Clinical Science Departments
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Member of the Duke Cancer Institute
·
2023 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Mechanisms and Therapeutic Potential of Human Cardiomyocyte Proliferation.
Journal Article J Cardiovasc Dev Dis · February 2, 2026 The limited capacity for cardiomyocyte proliferation in the adult human heart restricts its ability to recover from injury. Building on discoveries in regenerative model systems, such as zebrafish and neonatal mice, reactivation of a latent potential for c ... Full text Link to item CiteA gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress.
Journal Article Genome Res · November 3, 2025 A hallmark of heart disease is gene dysregulation and reactivation of fetal gene programs. Reactivation of these fetal programs has compensatory effects during heart failure, depending on the type and stage of the underlying cardiomyopathy. Thousands of pu ... Full text Link to item CiteRecent Grants
A Phase 2, adaptive, double-blinded, placebo-controlled, randomized, multi-center trial to evaluate the efficacy, safety and tolerability of intracoronary infusion of AB-1002 in adult subjects with New York Heart Association (NYHA) Class III
Clinical TrialCo-Principal Investigator · Awarded by AskBio · 2025 - 2030A Phase 2b/3, Adaptive, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Danicamtiv in Participants with Symptomatic Genetic and Familial Dilated Cardiomyopathy
Clinical TrialPrincipal Investigator · Awarded by Kardigan Inc. · 2026 - 2030Magnitude
Clinical TrialPrincipal Investigator · Awarded by Intellia Therapeutics, Inc. · 2024 - 2029View All Grants
Education
Duke University, School of Medicine ·
2005
M.D.