Journal ArticleAcad Med · August 1, 2023
Translational research is a data-driven process that involves transforming scientific laboratory- and clinic-based discoveries into products and activities with real-world impact to improve individual and population health. Successful execution of translat ...
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Journal ArticleJ Clin Transl Sci · February 2020
Navigating the research domain at an academic medical center can be challenging, even for seasoned investigators. To address this, Duke University launched two initiatives: (1) a research navigation "hotline" to provide brief assistance with a variety of r ...
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Journal ArticleTherapeutic innovation & regulatory science · January 2020
Competency standards for clinical research professionals are being developed across the enterprise, based largely on the Core Competency Framework put forth by the Joint Task Force for Clinical Trial Competency (JTF). In late 2016, representatives from org ...
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Journal ArticleJournal of Research Administration · January 1, 2020
Aligning job descriptions at Duke University Schools of Medicine and Nursing with the Joint Task Force for Clinical Trial Competencies ( JTFCTC) spurred additional related activities—namely, establishing professional pathways and career ladders for clinica ...
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Journal ArticleContemporary clinical trials · May 2016
Clinical research activities at academic medical centers are challenging to oversee. Without effective research administration, a continually evolving set of regulatory and institutional requirements can divert investigator and study team attention away fr ...
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Journal ArticleBMC Public Health · December 10, 2015
BACKGROUND: Many families rely on child care outside the home, making these settings important influences on child development. Nearly 1.5 million children in the U.S. spend time in family child care homes (FCCHs), where providers care for children in thei ...
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Journal ArticleAm J Manag Care · July 1, 2015
OBJECTIVES: To examine the relationship among use of an on-site employer-provided primary care medical home, and health services use and health plan costs for inpatient and outpatient services and pharmaceuticals. STUDY DESIGN: The study was a retrospectiv ...
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Journal ArticleChild Obes · June 2015
BACKGROUND: Community-based interventions are promising approaches to obesity prevention, but few studies have prospectively evaluated them. The aim of this study was to evaluate a natural experiment—a community intervention designed to promote active livi ...
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Journal ArticleInt J Health Geogr · February 6, 2015
BACKGROUND: This study examined whether objective measures of food, physical activity and built environment exposures, in home and non-home settings, contribute to children's body weight. Further, comparing GPS and GIS measures of environmental exposures a ...
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Journal ArticleJ Occup Environ Med · February 2015
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study, a randomized trial to evaluate the effectiveness of two employee weight management programs offered within Duke University and the Health System. METHODS: A total of 550 ...
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Journal ArticleJ Phys Act Health · February 2015
BACKGROUND: Young children's physical activity (PA) is influenced by their child care environment. This study assessed PA practices in centers from Massachusetts (MA) and Rhode Island (RI), compared them to best practice recommendations, and assessed diffe ...
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Journal ArticleContemp Clin Trials · January 2015
BACKGROUND: Obesity is a major public health problem for which early preventive interventions are needed. Large numbers of young children are enrolled in some form of child care program, making these facilities influential environments in children's develo ...
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Journal ArticleJ Acad Nutr Diet · November 2013
BACKGROUND: Children of obese parents are more likely to become obese than children of normal-weight parents. However, there is little information regarding the diet intakes of children of obese parents. OBJECTIVE: Our objective was to determine the diet q ...
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Journal ArticleInt J Obes (Lond) · October 2013
BACKGROUND: The effects of the home environment on child health behaviors related to obesity are unclear. PURPOSE: To examine the role of the home physical activity (PA) and food environment on corresponding outcomes in young children, and assess maternal ...
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Journal ArticleContemp Clin Trials · July 2013
BACKGROUND: The workplace can be an important setting for addressing obesity. An increasing number of employers offer weight management programs. PURPOSE: Present the design, rationale and baseline characteristics of the Steps to Health study (STH), a rand ...
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Journal ArticleBMC Public Health · April 18, 2013
BACKGROUND: Americans, including children, consume fewer fruit and vegetable servings than is recommended. Given that young children spend large amounts of time in child care centers, this may be an ideal venue for increasing consumption of and enthusiasm ...
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Journal ArticleInternational Journal of Obesity · 2013
Background:The effects of the home environment on child health behaviors related to obesity are unclear.Purpose:To examine the role of the home physical activity (PA) and food environment on corresponding outcomes in young children, and assess maternal edu ...
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Journal ArticleJ Acad Nutr Diet · January 2013
BACKGROUND: Postpartum weight retention is a risk factor for long-term weight gain. Encouraging new mothers to consume a healthy diet may result in weight loss. OBJECTIVE: To assess predictors of diet quality during the early postpartum period; to determin ...
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Journal ArticleAcad Pediatr · 2013
BACKGROUND: The American Academy of Pediatrics (AAP) has issued specific behavioral recommendations to prevent obesity. It is unclear how often high-risk preschoolers and overweight mothers meet recommended behavior goals and whether meeting these goals is ...
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Journal ArticleWomen Health · 2013
Few studies have assessed physical activity at multiple time points in the postpartum period or used both self-reported and objective measures of assessment. The purpose of this study was to describe physical activity and sedentary behavior at two time poi ...
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Journal ArticleFam Pract · October 2012
BACKGROUND: Physician counselling may help patients increase physical activity, improve nutrition and lose weight. However, physicians have low outcome expectations that patients will change. The aims are to describe the accuracy of physicians' outcome exp ...
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Journal ArticlePrev Med · September 2012
OBJECTIVE: The study presents the immediate post-intervention results of Kids and Adults Now - Defeat Obesity!, a randomized controlled trial to enhance healthy lifestyle behaviors in mother-preschooler (2-5 years old) dyads in North Carolina (2007-2011). ...
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Journal ArticleSoc Sci Med · July 2012
While the prevalence, comorbidity, risk profile and health care utilization for late-life depression have been described for many Western countries, much less is known about the recent epidemiology of late-life depression in East Asian countries such as Ko ...
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Journal ArticlePatient Educ Couns · December 2011
OBJECTIVE: Examine primary care physicians' use of counseling techniques when treating overweight and obese patients and the association with mediators of behavior change as well as change in nutrition, exercise, and weight loss attempts. METHODS: We audio ...
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Journal ArticlePatient Educ Couns · December 2011
OBJECTIVE: Evidence suggests that physicians' use of motivational interviewing (MI) techniques helps patients lose weight. We assessed patient, physician, relationship, and systems predictors of length of weight-loss discussions and whether physicians' use ...
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Journal ArticlePrev Chronic Dis · November 2011
INTRODUCTION: Few studies have examined the correlates of objectively measured amounts of sedentary time and physical activity in young children. We evaluated the demographic, biological, behavioral, social, and environmental correlates of the amount of se ...
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Journal ArticleJ Womens Health (Larchmt) · November 2011
BACKGROUND: In the United States, about two thirds of women of reproductive age are overweight or obese. Postpartum is a transitional period. Life changes during this time can put mothers under high levels of stress when interpersonal support is inadequate ...
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Journal ArticleJ Phys Act Health · September 2011
BACKGROUND: Low physical activity (PA) during the postpartum period is associated with weight retention. While patterns of PA have been examined in normal weight women during this period, little is known about PA among overweight and obese women. The aim o ...
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Journal ArticleContemp Clin Trials · May 2011
BACKGROUND: Prevention of childhood obesity is a public health priority. Parents influence a child's weight by modeling healthy behaviors, controlling food availability and activity opportunities, and appropriate feeding practices. Thus interventions shoul ...
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Journal ArticleJ Matern Fetal Neonatal Med · January 2011
OBJECTIVE: Societal pressures against smoking during pregnancy may lead to a reduction in disclosure of smoking status. The objective of this study was to compare prevalence of smoking at prenatal intake by self-report with anonymous biochemical validation ...
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Journal ArticleJ Am Diet Assoc · January 2011
BACKGROUND: Weight gain in the postpartum period is a risk factor for long-term obesity. Investigations of dietary intake among lactating and nonlactating overweight women might identify nutritional concerns specific to this population. OBJECTIVE: To compa ...
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Journal ArticleJ Sex Marital Ther · 2011
The authors assessed sexual functioning among treatment-seeking obese men (n = 91) and women (n = 134) using the comprehensive validated Sexual Functioning Questionnaire. Scores were lower for women than for men, indicating reduced sexual functioning. Men' ...
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Journal ArticleAm J Prev Med · October 2010
BACKGROUND: Physicians are encouraged to counsel overweight and obese patients to lose weight. PURPOSE: It was examined whether discussing weight and use of motivational interviewing techniques (e.g., collaborating, reflective listening) while discussing w ...
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Journal ArticleWomens Health Issues · 2010
BACKGROUND: Pregnancy is associated with weight gain and obesity. The aim of this study was to identify the effect of parity and other factors on motivation to change diet to lose weight in a cohort of overweight and obese postpartum women. STUDY DESIGN: A ...
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Journal ArticleEthn Health · 2010
OBJECTIVE: Pregnancy may be a time when US Latino expectant fathers consider quitting smoking. A 'teachable moment' is theorized to increase motivation to change a behavior through increased risk perceptions, emotional responses, and changes in self-image. ...
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Journal ArticleAm J Prev Med · September 2009
BACKGROUND: Pregnancy may contribute to overweight and obesity. PURPOSE: The primary objective of Active Mothers Postpartum was to promote a reduction in BMI through 24-months postpartum via sustainable lifestyle changes. DESIGN: Behavioral intervention RC ...
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Journal ArticleJ Adolesc Health · August 2009
Physicians should counsel overweight adolescents about nutrition and exercise. We audio recorded 30 physician-adolescent encounters. Female, older, normal-weight physicians and pediatricians were more Motivational Interviewing (MI) adherent. When physician ...
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Journal ArticleNicotine Tob Res · May 2009
INTRODUCTION: This secondary analysis examined the association between adherence to nicotine replacement therapy (NRT) and smoking cessation among pregnant smokers enrolled in Baby Steps, an open-label randomized controlled trial testing cognitive-behavior ...
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Journal ArticleJ Womens Health (Larchmt) · December 2008
BACKGROUND: Pregnancy and the postpartum period have been suggested as important contributors to overweight and obesity among women. This paper presents the design, rationale, and baseline participant characteristics of a randomized controlled intervention ...
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Journal ArticleJ Fam Pract · December 2007
PURPOSE: This study explores how weight-related topics are discussed between physicians and their overweight and obese female patients. METHODS: We surveyed and audio-recorded preventive health and chronic care visits with 25 overweight and obese female pa ...
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Journal ArticleAm J Prev Med · October 2007
BACKGROUND: This study examines whether adding nicotine replacement therapy (NRT) to cognitive-behavioral therapy (CBT) for pregnant smokers increases rates of smoking cessation. METHODS: An open-label randomized trial (Baby Steps, n=181) of CBT-only versu ...
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Journal ArticleAm J Health Promot · 2007
PURPOSE: Physicians are expected to discuss weight loss with overweight and obese patients. Physicians' beliefs, outcome expectancies, and strategies for addressing weight with patients have not been examined. DESIGN: Two focus groups of family physicians ...
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Journal ArticleNicotine Tob Res · August 2006
Improvements in smoking cessation interventions for pregnant smokers are needed. One major step is to examine the potential effectiveness of nicotine replacement therapy (NRT). The potential benefits of providing pregnant women with NRT to help them quit s ...
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Journal ArticleJournal of health communication · September 2005
Intervening with families is a promising strategy for addressing the continuing problem of adult and youth tobacco use. A four-step formative process was used to develop an innovative self-directed family-based intervention: (1) planning and strategy devel ...
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Journal ArticleChronic Dis Can · 2005
Depression in elderly Canadians is an important but often unrecognized public health problem. Numerous studies have examined depression in the general community, but studies of depression in the elderly have generally been small and limited. The Canadian S ...
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Journal ArticleEating behaviors · November 2004
Although there is empirical support for the association between smoking, disordered eating, and subsequent weight gain upon smoking cessation, there have been no prospective studies to track changes in eating patterns during smoking abstinence and explore ...
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Journal ArticleHuman psychopharmacology · October 2004
To determine whether smokers with a history of depression are differentially susceptible to smoking withdrawal, depressed mood induction and/or hypothalamic-pituitary-adrenal (HPA) axis dysregulation during smoking abstinence, 24 women smokers with and wit ...
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Journal ArticleAm J Prev Med · August 2003
BACKGROUND: Concerns about weight gain have been a commonly cited barrier to cessation among white, affluent, female populations, but less is known about this relationship among minority smokers and those with low incomes. Although smoking cessation is str ...
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Journal ArticleMil Med · April 2003
Overweight and obesity among soldiers and their dependents have increased over the last decade, mirroring rates in the general population. In general, few programs that result in sustained weight loss have been evaluated, although effective interventions c ...
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Journal ArticleJournal of substance abuse treatment · January 2003
To test the efficacy of sustained nicotine patch use among at-risk smokers, 55 smokers with a history of abstinence-induced depressed mood were randomly assigned to either Nicotine Maintenance or Standard Treatment following preliminary high-dose patch tre ...
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Journal ArticleAddictive behaviors · September 2001
To investigate attitudes about weight as they interact with smoking in African American women, we analyzed data from two independent samples of white and African American women smokers--one assembled via a national random-digit-dialing survey, the other co ...
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Journal ArticleJournal of addictive diseases · January 2001
The emergence of depression early in a quit attempt and its relationship to ability to maintain abstinence were studied in 99 depressed and non-depressed women smokers. Participants rated withdrawal symptomatology during a baseline week and the first two w ...
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Journal ArticleAddictive behaviors · September 2000
When women smokers become pregnant, they are asked to control weight gain and at the same time to relinquish an addictive drug with weight suppressing effects. For women with serious body image concerns or a history of unhealthful eating patterns, smoking ...
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Journal ArticleEating Behaviors · January 1, 2000
The impact of concerns about postcessation weight gain is sometimes minimized based on the finding of many (though not all) studies of an association between actual weight gain and successful quitting. A possible explanation is that many weight-concerned i ...
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Journal ArticleAddiction · April 1998
Aims. Recent research suggests that people who become smokers may be more sensitive to the positive effects of nicotine than those who do not take up smoking . Design and setting. The present study was designed to investigate this hypothesis by que ...
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