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Rebecca Brouwer

Assist VP, Research & Innovation
School of Medicine
Box 102846, 2812 Erwin Rd, Durham, NC 27705
671 W 11th Ave, Eugene, OR 97402

Selected Publications


Needles in a Haystack: Finding Qualitative and Quantitative Collaborators in Academic Medical Centers.

Journal Article Acad Med · August 1, 2023 Translational research is a data-driven process that involves transforming scientific laboratory- and clinic-based discoveries into products and activities with real-world impact to improve individual and population health. Successful execution of translat ... Full text Link to item Cite

Supporting researchers through full-service hotline and consultation services: Success in simplicity, customization, and staffing.

Journal Article J Clin Transl Sci · February 2020 Navigating the research domain at an academic medical center can be challenging, even for seasoned investigators. To address this, Duke University launched two initiatives: (1) a research navigation "hotline" to provide brief assistance with a variety of r ... Full text Open Access Link to item Cite

Leveling the Joint Task Force Core Competencies for Clinical Research Professionals.

Journal Article Therapeutic innovation & regulatory science · January 2020 Competency standards for clinical research professionals are being developed across the enterprise, based largely on the Core Competency Framework put forth by the Joint Task Force for Clinical Trial Competency (JTF). In late 2016, representatives from org ... Full text Cite

Professional development for clinical research professionals: Implementation of a competency-based assessment model

Journal Article Journal of Research Administration · January 1, 2020 Aligning job descriptions at Duke University Schools of Medicine and Nursing with the Joint Task Force for Clinical Trial Competencies ( JTFCTC) spurred additional related activities—namely, establishing professional pathways and career ladders for clinica ... Cite

Leveling the joint task force core competencies for clinical research professionals

Journal Article Therapeutic Innovation & Regulatory Science · 2018 Cite

MyResearchHome@ Duke—launch and adoption of a portal for the research community.

Conference Journal of Clinical and Translational Science · January 9, 2017 Cite

Using Competencies to Transform Clinical Research Job Classifications

Journal Article Journal of Research Administration · 2017 Cite

Academic Preparation in Clinical Research

Journal Article Clinical Researcher · December 9, 2016 Full text Open Access Link to item Cite

Retooling institutional support infrastructure for clinical research.

Journal Article Contemporary clinical trials · May 2016 Clinical research activities at academic medical centers are challenging to oversee. Without effective research administration, a continually evolving set of regulatory and institutional requirements can divert investigator and study team attention away fr ... Full text Cite

Application of the Intervention Mapping protocol to develop Keys, a family child care home intervention to prevent early childhood obesity.

Journal Article BMC Public Health · December 10, 2015 BACKGROUND: Many families rely on child care outside the home, making these settings important influences on child development. Nearly 1.5 million children in the U.S. spend time in family child care homes (FCCHs), where providers care for children in thei ... Full text Open Access Link to item Cite

Worksite medical home: health services use and claim costs.

Journal Article Am J Manag Care · July 1, 2015 OBJECTIVES: To examine the relationship among use of an on-site employer-provided primary care medical home, and health services use and health plan costs for inpatient and outpatient services and pharmaceuticals. STUDY DESIGN: The study was a retrospectiv ... Open Access Link to item Cite

A community-based intervention increases physical activity and reduces obesity in school-age children in North Carolina.

Journal Article Child Obes · June 2015 BACKGROUND: Community-based interventions are promising approaches to obesity prevention, but few studies have prospectively evaluated them. The aim of this study was to evaluate a natural experiment—a community intervention designed to promote active livi ... Full text Open Access Link to item Cite

Associations between BMI and home, school and route environmental exposures estimated using GPS and GIS: do we see evidence of selective daily mobility bias in children?

Journal Article Int J Health Geogr · February 6, 2015 BACKGROUND: This study examined whether objective measures of food, physical activity and built environment exposures, in home and non-home settings, contribute to children's body weight. Further, comparing GPS and GIS measures of environmental exposures a ... Full text Open Access Link to item Cite

Steps to Health employee weight management randomized control trial: short-term follow-up results.

Journal Article J Occup Environ Med · February 2015 OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study, a randomized trial to evaluate the effectiveness of two employee weight management programs offered within Duke University and the Health System. METHODS: A total of 550 ... Full text Open Access Link to item Cite

Physical activity-related and weather-related practices of child care centers from 2 states.

Journal Article J Phys Act Health · February 2015 BACKGROUND: Young children's physical activity (PA) is influenced by their child care environment. This study assessed PA practices in centers from Massachusetts (MA) and Rhode Island (RI), compared them to best practice recommendations, and assessed diffe ... Full text Open Access Link to item Cite

The keys to healthy family child care homes intervention: study design and rationale.

Journal Article Contemp Clin Trials · January 2015 BACKGROUND: Obesity is a major public health problem for which early preventive interventions are needed. Large numbers of young children are enrolled in some form of child care program, making these facilities influential environments in children's develo ... Full text Open Access Link to item Cite

Diet quality of overweight and obese mothers and their preschool children.

Journal Article J Acad Nutr Diet · November 2013 BACKGROUND: Children of obese parents are more likely to become obese than children of normal-weight parents. However, there is little information regarding the diet intakes of children of obese parents. OBJECTIVE: Our objective was to determine the diet q ... Full text Link to item Cite

The effect of the home environment on physical activity and dietary intake in preschool children.

Journal Article Int J Obes (Lond) · October 2013 BACKGROUND: The effects of the home environment on child health behaviors related to obesity are unclear. PURPOSE: To examine the role of the home physical activity (PA) and food environment on corresponding outcomes in young children, and assess maternal ... Full text Open Access Link to item Cite

The steps to health employee weight management randomized control trial: rationale, design and baseline characteristics.

Journal Article Contemp Clin Trials · July 2013 BACKGROUND: The workplace can be an important setting for addressing obesity. An increasing number of employers offer weight management programs. PURPOSE: Present the design, rationale and baseline characteristics of the Steps to Health study (STH), a rand ... Full text Link to item Cite

Watch me grow: a garden-based pilot intervention to increase vegetable and fruit intake in preschoolers.

Journal Article BMC Public Health · April 18, 2013 BACKGROUND: Americans, including children, consume fewer fruit and vegetable servings than is recommended. Given that young children spend large amounts of time in child care centers, this may be an ideal venue for increasing consumption of and enthusiasm ... Full text Open Access Link to item Cite

The effect of the home environment on physical activity and dietary intake in preschool children

Journal Article International Journal of Obesity · 2013 Background:The effects of the home environment on child health behaviors related to obesity are unclear.Purpose:To examine the role of the home physical activity (PA) and food environment on corresponding outcomes in young children, and assess maternal edu ... Full text Cite

Diet quality and weight change among overweight and obese postpartum women enrolled in a behavioral intervention program.

Journal Article J Acad Nutr Diet · January 2013 BACKGROUND: Postpartum weight retention is a risk factor for long-term weight gain. Encouraging new mothers to consume a healthy diet may result in weight loss. OBJECTIVE: To assess predictors of diet quality during the early postpartum period; to determin ... Full text Link to item Cite

Do high-risk preschoolers or overweight mothers meet AAP-recommended behavioral goals for reducing obesity?

Journal Article Acad Pediatr · 2013 BACKGROUND: The American Academy of Pediatrics (AAP) has issued specific behavioral recommendations to prevent obesity. It is unclear how often high-risk preschoolers and overweight mothers meet recommended behavior goals and whether meeting these goals is ... Full text Link to item Cite

Changes in physical activity among postpartum overweight and obese women: results from the KAN-DO Study.

Journal Article Women Health · 2013 Few studies have assessed physical activity at multiple time points in the postpartum period or used both self-reported and objective measures of assessment. The purpose of this study was to describe physical activity and sedentary behavior at two time poi ... Full text Link to item Cite

Can physicians accurately predict which patients will lose weight, improve nutrition and increase physical activity?

Journal Article Fam Pract · October 2012 BACKGROUND: Physician counselling may help patients increase physical activity, improve nutrition and lose weight. However, physicians have low outcome expectations that patients will change. The aims are to describe the accuracy of physicians' outcome exp ... Full text Link to item Cite

Parent-focused change to prevent obesity in preschoolers: results from the KAN-DO study.

Journal Article Prev Med · September 2012 OBJECTIVE: The study presents the immediate post-intervention results of Kids and Adults Now - Defeat Obesity!, a randomized controlled trial to enhance healthy lifestyle behaviors in mother-preschooler (2-5 years old) dyads in North Carolina (2007-2011). ... Full text Link to item Cite

Predictors of and health services utilization related to depressive symptoms among elderly Koreans.

Journal Article Soc Sci Med · July 2012 While the prevalence, comorbidity, risk profile and health care utilization for late-life depression have been described for many Western countries, much less is known about the recent epidemiology of late-life depression in East Asian countries such as Ko ... Full text Link to item Cite

Effects of counseling techniques on patients' weight-related attitudes and behaviors in a primary care clinic.

Journal Article Patient Educ Couns · December 2011 OBJECTIVE: Examine primary care physicians' use of counseling techniques when treating overweight and obese patients and the association with mediators of behavior change as well as change in nutrition, exercise, and weight loss attempts. METHODS: We audio ... Full text Link to item Cite

Predictors of weight loss communication in primary care encounters.

Journal Article Patient Educ Couns · December 2011 OBJECTIVE: Evidence suggests that physicians' use of motivational interviewing (MI) techniques helps patients lose weight. We assessed patient, physician, relationship, and systems predictors of length of weight-loss discussions and whether physicians' use ... Full text Link to item Cite

Correlates of sedentary time and physical activity among preschool-aged children.

Journal Article Prev Chronic Dis · November 2011 INTRODUCTION: Few studies have examined the correlates of objectively measured amounts of sedentary time and physical activity in young children. We evaluated the demographic, biological, behavioral, social, and environmental correlates of the amount of se ... Open Access Link to item Cite

Unmet social support for healthy behaviors among overweight and obese postpartum women: results from the Active Mothers Postpartum Study.

Journal Article J Womens Health (Larchmt) · November 2011 BACKGROUND: In the United States, about two thirds of women of reproductive age are overweight or obese. Postpartum is a transitional period. Life changes during this time can put mothers under high levels of stress when interpersonal support is inadequate ... Full text Link to item Cite

Postpartum physical activity in overweight and obese women.

Journal Article J Phys Act Health · September 2011 BACKGROUND: Low physical activity (PA) during the postpartum period is associated with weight retention. While patterns of PA have been examined in normal weight women during this period, little is known about PA among overweight and obese women. The aim o ... Full text Link to item Cite

Kids and adults now! Defeat Obesity (KAN-DO): rationale, design and baseline characteristics.

Journal Article Contemp Clin Trials · May 2011 BACKGROUND: Prevention of childhood obesity is a public health priority. Parents influence a child's weight by modeling healthy behaviors, controlling food availability and activity opportunities, and appropriate feeding practices. Thus interventions shoul ... Full text Link to item Cite

Smoking prevalence in early pregnancy: comparison of self-report and anonymous urine cotinine testing.

Journal Article J Matern Fetal Neonatal Med · January 2011 OBJECTIVE: Societal pressures against smoking during pregnancy may lead to a reduction in disclosure of smoking status. The objective of this study was to compare prevalence of smoking at prenatal intake by self-report with anonymous biochemical validation ... Full text Link to item Cite

Comparison of dietary intake of overweight postpartum mothers practicing breastfeeding or formula feeding.

Journal Article J Am Diet Assoc · January 2011 BACKGROUND: Weight gain in the postpartum period is a risk factor for long-term obesity. Investigations of dietary intake among lactating and nonlactating overweight women might identify nutritional concerns specific to this population. OBJECTIVE: To compa ... Full text Link to item Cite

Sexual functioning in obese adults enrolling in a weight loss study.

Journal Article J Sex Marital Ther · 2011 The authors assessed sexual functioning among treatment-seeking obese men (n = 91) and women (n = 134) using the comprehensive validated Sexual Functioning Questionnaire. Scores were lower for women than for men, indicating reduced sexual functioning. Men' ... Full text Link to item Cite

Physician communication techniques and weight loss in adults: Project CHAT.

Journal Article Am J Prev Med · October 2010 BACKGROUND: Physicians are encouraged to counsel overweight and obese patients to lose weight. PURPOSE: It was examined whether discussing weight and use of motivational interviewing techniques (e.g., collaborating, reflective listening) while discussing w ... Full text Link to item Cite

Multiparity is associated with high motivation to change diet among overweight and obese postpartum women.

Journal Article Womens Health Issues · 2010 BACKGROUND: Pregnancy is associated with weight gain and obesity. The aim of this study was to identify the effect of parity and other factors on motivation to change diet to lose weight in a cohort of overweight and obese postpartum women. STUDY DESIGN: A ... Full text Link to item Cite

Is pregnancy a teachable moment for smoking cessation among US Latino expectant fathers? A pilot study.

Journal Article Ethn Health · 2010 OBJECTIVE: Pregnancy may be a time when US Latino expectant fathers consider quitting smoking. A 'teachable moment' is theorized to increase motivation to change a behavior through increased risk perceptions, emotional responses, and changes in self-image. ... Full text Link to item Cite

Active Mothers Postpartum: a randomized controlled weight-loss intervention trial.

Journal Article Am J Prev Med · September 2009 BACKGROUND: Pregnancy may contribute to overweight and obesity. PURPOSE: The primary objective of Active Mothers Postpartum was to promote a reduction in BMI through 24-months postpartum via sustainable lifestyle changes. DESIGN: Behavioral intervention RC ... Full text Link to item Cite

Primary care physicians' discussions of weight-related topics with overweight and obese adolescents: results from the Teen CHAT Pilot study.

Journal Article J Adolesc Health · August 2009 Physicians should counsel overweight adolescents about nutrition and exercise. We audio recorded 30 physician-adolescent encounters. Female, older, normal-weight physicians and pediatricians were more Motivational Interviewing (MI) adherent. When physician ... Full text Link to item Cite

Adherence to nicotine replacement therapy among pregnant smokers.

Journal Article Nicotine Tob Res · May 2009 INTRODUCTION: This secondary analysis examined the association between adherence to nicotine replacement therapy (NRT) and smoking cessation among pregnant smokers enrolled in Baby Steps, an open-label randomized controlled trial testing cognitive-behavior ... Full text Link to item Cite

Active Mothers Postpartum (AMP): rationale, design, and baseline characteristics.

Journal Article J Womens Health (Larchmt) · December 2008 BACKGROUND: Pregnancy and the postpartum period have been suggested as important contributors to overweight and obesity among women. This paper presents the design, rationale, and baseline participant characteristics of a randomized controlled intervention ... Full text Link to item Cite

Empathy goes a long way in weight loss discussions.

Journal Article J Fam Pract · December 2007 PURPOSE: This study explores how weight-related topics are discussed between physicians and their overweight and obese female patients. METHODS: We surveyed and audio-recorded preventive health and chronic care visits with 25 overweight and obese female pa ... Link to item Cite

Nicotine replacement and behavioral therapy for smoking cessation in pregnancy.

Journal Article Am J Prev Med · October 2007 BACKGROUND: This study examines whether adding nicotine replacement therapy (NRT) to cognitive-behavioral therapy (CBT) for pregnant smokers increases rates of smoking cessation. METHODS: An open-label randomized trial (Baby Steps, n=181) of CBT-only versu ... Full text Link to item Cite

Physicians' beliefs about discussing obesity: results from focus groups.

Journal Article Am J Health Promot · 2007 PURPOSE: Physicians are expected to discuss weight loss with overweight and obese patients. Physicians' beliefs, outcome expectancies, and strategies for addressing weight with patients have not been examined. DESIGN: Two focus groups of family physicians ... Full text Link to item Cite

Challenges and solutions for recruiting pregnant smokers into a nicotine replacement therapy trial.

Journal Article Nicotine Tob Res · August 2006 Improvements in smoking cessation interventions for pregnant smokers are needed. One major step is to examine the potential effectiveness of nicotine replacement therapy (NRT). The potential benefits of providing pregnant women with NRT to help them quit s ... Full text Link to item Cite

Comparison of self-reported smoking status and anonymous urinary cotinine testing in pregnancy

Conference American Journal of Obstetrics and Gynecology · December 2005 Full text Cite

Formative development of an intervention to stop family tobacco use: the Parents and Children Talking (PACT) intervention.

Journal Article Journal of health communication · September 2005 Intervening with families is a promising strategy for addressing the continuing problem of adult and youth tobacco use. A four-step formative process was used to develop an innovative self-directed family-based intervention: (1) planning and strategy devel ... Full text Cite

Prevalence and predictors of depression in elderly Canadians: The Canadian Study of Health and Aging.

Journal Article Chronic Dis Can · 2005 Depression in elderly Canadians is an important but often unrecognized public health problem. Numerous studies have examined depression in the general community, but studies of depression in the elderly have generally been small and limited. The Canadian S ... Link to item Cite

Effects of disordered eating and obesity on weight, craving, and food intake during ad libitum smoking and abstinence.

Journal Article Eating behaviors · November 2004 Although there is empirical support for the association between smoking, disordered eating, and subsequent weight gain upon smoking cessation, there have been no prospective studies to track changes in eating patterns during smoking abstinence and explore ... Full text Cite

Depression, smoking abstinence and HPA function in women smokers.

Journal Article Human psychopharmacology · October 2004 To determine whether smokers with a history of depression are differentially susceptible to smoking withdrawal, depressed mood induction and/or hypothalamic-pituitary-adrenal (HPA) axis dysregulation during smoking abstinence, 24 women smokers with and wit ... Full text Cite

Weight and smoking cessation among low-income African Americans.

Journal Article Am J Prev Med · August 2003 BACKGROUND: Concerns about weight gain have been a commonly cited barrier to cessation among white, affluent, female populations, but less is known about this relationship among minority smokers and those with low incomes. Although smoking cessation is str ... Full text Link to item Cite

Interest in healthy diet and physical activity interventions peripartum among female partners of active duty military.

Journal Article Mil Med · April 2003 Overweight and obesity among soldiers and their dependents have increased over the last decade, mirroring rates in the general population. In general, few programs that result in sustained weight loss have been evaluated, although effective interventions c ... Link to item Cite

Prolonged nicotine patch use in quitters with past abstinence-induced depressed mood.

Journal Article Journal of substance abuse treatment · January 2003 To test the efficacy of sustained nicotine patch use among at-risk smokers, 55 smokers with a history of abstinence-induced depressed mood were randomly assigned to either Nicotine Maintenance or Standard Treatment following preliminary high-dose patch tre ... Full text Cite

Race differences in weight concerns among women smokers: results from two independent samples.

Journal Article Addictive behaviors · September 2001 To investigate attitudes about weight as they interact with smoking in African American women, we analyzed data from two independent samples of white and African American women smokers--one assembled via a national random-digit-dialing survey, the other co ... Full text Cite

Emergence of depression during early abstinence in depressed and non-depressed women smokers.

Journal Article Journal of addictive diseases · January 2001 The emergence of depression early in a quit attempt and its relationship to ability to maintain abstinence were studied in 99 depressed and non-depressed women smokers. Participants rated withdrawal symptomatology during a baseline week and the first two w ... Full text Cite

Weight concerns in women smokers during pregnancy and postpartum.

Journal Article Addictive behaviors · September 2000 When women smokers become pregnant, they are asked to control weight gain and at the same time to relinquish an addictive drug with weight suppressing effects. For women with serious body image concerns or a history of unhealthful eating patterns, smoking ... Full text Cite

Short-term weight gain in abstaining women smokers

Journal Article Journal of Substance Abuse Treatment · June 2000 Full text Cite

"Prequit attrition" among weight-concerned women smokers

Journal Article Eating Behaviors · January 1, 2000 The impact of concerns about postcessation weight gain is sometimes minimized based on the finding of many (though not all) studies of an association between actual weight gain and successful quitting. A possible explanation is that many weight-concerned i ... Full text Cite

Initial Exposure to Nicotine in College-Age Women Smokers and Never-Smokers

Journal Article Journal of Addictive Diseases · September 3, 1999 Full text Cite

Early experiences with tobacco among women smokers, ex‐smokers, and never‐smokers

Journal Article Addiction · April 1998 Aims. Recent research suggests that people who become smokers may be more sensitive to the positive effects of nicotine than those who do not take up smoking . Design and setting. The present study was designed to investigate this hypothesis by que ... Full text Cite