Overview
Our lab is interested in understanding the neural basis of simple decision-making processes. We use Drosophila egg-laying site selection as our model system. To understand how the Drosophila brain assesses and ranks the values of egg-laying options, we use a combined approach that includes high-throughput optogenetics-based behavioral screen, automated (machine vision) behavioral tracking of single animals, molecular genetic tools to identify critical circuit components, and calcium imaging and anatomical tracing techniques to determine the physical and functional connectivity of identified circuit components.
Current Appointments & Affiliations
Associate Professor of Neurobiology
·
2016 - Present
Neurobiology,
Basic Science Departments
Recent Publications
Insect neurobiology: Oviposition crowd control.
Journal Article Curr Biol · January 8, 2024 A new study examines how Helicoverpa armigera females detect chemicals released by conspecific eggs in order to avoid laying more eggs on the same substrate. This work opens new avenues for basic research inquiries and offers a potential strategy for contr ... Full text Link to item CiteA functional division of Drosophila sweet taste neurons that is value-based and task-specific.
Journal Article Proc Natl Acad Sci U S A · January 18, 2022 Sucrose is an attractive feeding substance and a positive reinforcer for Drosophila But Drosophila females have been shown to robustly reject a sucrose-containing option for egg-laying when given a choice between a plain and a sucrose-containing option in ... Full text Link to item CiteA neuropeptidergic circuit gates selective escape behavior of Drosophila larvae.
Journal Article Curr Biol · January 10, 2022 Animals display selective escape behaviors when faced with environmental threats. Selection of the appropriate response by the underlying neuronal network is key to maximizing chances of survival, yet the underlying network mechanisms are so far not fully ... Full text Link to item CiteRecent Grants
Neurobiology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029Basic predoctoral training in neuroscience
Inst. Training Prgm or CMETraining Faculty · Awarded by National Institutes of Health · 1992 - 2018Genetic Dissection of an Avoidance Circuit in Drosophila
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2018View All Grants
Education, Training & Certifications
Stanford University ·
2002
Ph.D.