Overview
My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.
Current Appointments & Affiliations
Professor Emeritus of Psychiatry and Behavioral Sciences
·
2022 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Recent Publications
Genome-Wide Genetic Analysis of Dropout in a Controlled Exercise Intervention in Sedentary Adults With Overweight or Obesity and Cardiometabolic Disease.
Journal Article Ann Behav Med · April 11, 2024 BACKGROUND: Despite the benefits of exercise, many individuals are unable or unwilling to adopt an exercise intervention. PURPOSE: The purpose of this analysis was to identify putative genetic variants associated with dropout from exercise training interve ... Full text Open Access Link to item CiteRelationship Between Psychosocial Stress and Blood Pressure: The National Heart, Lung, and Blood Institute Family Heart Study.
Journal Article SAGE Open Nurs · 2022 INTRODUCTION: Various domains of psychosocial stress have been significantly related to blood pressure. However, ambiguity is present in how these relationships are defined in the literature. OBJECTIVE: To add to the existing literature and examine the rel ... Full text Open Access Link to item CiteHostility and Health
Chapter · January 1, 2022 Hostility has verified links to poor health outcomes with a particular impact on coronary artery disease and mortality due to all causes. Hostility is a global term encapsulating hostile interpretations of the actions of others, angry reactions to perceive ... Full text CiteRecent Grants
Genes, Environmental Stressors, and the Biobehavioral Pathways to CVD
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 2021Exploring the Role of Social Environments for the Prevention of Hypertension among Black Females with a History of Chonic Stress
FellowshipCollaborator · Awarded by National Institutes of Health · 2019 - 2020An Innovative Model to Predict Readmissions in Adults with Cardiovascular Disease
ResearchCollaborator · Awarded by National Institutes of Health · 2013 - 2018View All Grants
Education, Training & Certifications
Yale University ·
1967
M.D.