Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.H.S., Duke University School of Medicine 2009
  • Ph.D., Paulista Medical School, University of Sao Paulo (Brazil) 2006
  • M.D., University of Santo Amaro (Brazil) 2001
• 

  Duke Appointment History

  • Associate Professor of Medicine, Medicine, Cardiology, Medicine 2013 - 2016
  • Adjunct Assistant Professor in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2009 - 2013
• Recognition
• 

  In the News

  • MAR 18, 2019

    Duke Health News

    When Less is More: Some Heart Patients Should Skip Aspirin as Part of Treatment

  • MAR 15, 2019

    Duke Health News

    Your Treatment for Heart Disease May Not Be Backed by Good Science

  • AUG 28, 2017

    Duke Health News

    Education and Monitoring Improves the Use of Stroke-Prevention Therapies
• Expertise
• 

  Global Scholarship

  • Expertise

    • Brazil (Country) 

  • Research

    • Brazil (Country) 

  • Teaching

    • Brazil (Country) 
• Research
• 

  Selected Grants

  • Trial to Assess Chelation Therapy 2 (TACT2) DCC awarded by National Institutes of Health 2015 - 2021
  • Sanofi SOTA Outcomes EFC15156 awarded by Sanofi US 2018 - 2021
  • Omecamtiv Mecarbil in Heart Failure awarded by Cytokinetics, Inc. 2018 - 2021
  • ASCEND_protocol 205270 awarded by GlaxoSmithKline 2017 - 2020
  • GSK-CKD program_CEC awarded by GlaxoSmithKline 2017 - 2020
  • DCRI-Stanford CEC Summit awarded by Baim Institute for Clinical Research 2018 - 2020
  • DCRI-Stanford CEC Summit awarded by WIRB-Copernicus Group 2018 - 2020
  • DCRI-Stanford Symposium awarded by AG Mednet 2018 - 2020
  • DCRI-Stanford Symposium awarded by Language Scientific, Inc. 2018 - 2020
  • A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, PK, and PD Effects of REGN2477-1033 in Obese Patients with Type 2 Diabetes Mellitus awarded by Regeneron Pharmaceuticals, Inc. 2018 - 2020
  • Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
  • Lilly GPGB Diabetes Study awarded by Eli Lilly and Company 2017 - 2019
  • AMG785-2015242 awarded by Amgen, Inc. 2017 - 2018
  • HeartRescue Brazil (RAPIDO) awarded by Research Triangle Institute International 2016 - 2018
  • CEC Adjudications for Lilly GIP_GLP1 awarded by Eli Lilly and Company 2017 - 2018
  • a retrospective re-review of all negatively adjudicated events (NAE) across three (3) protocols/studies awarded by Amgen, Inc. 2018
  • Educational Preceptorship Agreement awarded by Pfizer, Inc. 2017 - 2018
  • Bacteremia Modification 14 awarded by National Institutes of Health 2009 - 2017
  • Mod 11 for Option 3 - Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2017
  • Modification No 13 Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2017
  • GBGJ Dulaglutide_CEC awarded by Eli Lilly and Company 2016 - 2017
  • Modification No. 8 - Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2016
• Publications & Artistic Works
• 

  Selected Publications

  • Books

    • Guimarães, H. P., A. D. Zazula, R. D. Lopes, and O. Berwanger. Practical Guidance for Patients with Acute Coronary Syndrome. San Paulo: Athenu, 2014.
    • Lopes, R. D., and R. A. Harrington, eds. Understanding Clinical Trials (Portuguese). New York: McGraw-Hill, 2014.
    • Lopes, R. D., and R. A. Harrington, eds. Understanding Clinical Trials. New York: McGraw-Hill, 2013.
    • Calff, R. M., and M. Roe. Acute Coronary Syndromes: ACE Essentials. Physicians Press, 2010.
    • Calff, R. M., and M. Roe. Acute Coronary Syndromes: ACE Essentials. Physicians Press, 2010.
    • Lopes, R. D. Acid-base and Hydro-electrolytic Balance. Editora Atheneu, 2009.
    • Lopes, A. C., R. D. Lopes, and F. Freire. Ambulatory Internal Medicine. Ed Sao Paulo: Editora Manolle, 2007.
    • Guimaraes, H. P., R. D. Lopes, and A. C. Lopes. Cardio-Respiratory Arrest. Ed Sao Paulo: Editora Atheneu, 2005.

  • Academic Articles

    • Pokorney, SD, and Lopes, RD. "Atrial fibrillation: what do we know about screening and what do we not know about treatment?(Accepted)." Heart (British Cardiac Society) 105, no. 11 (June 2019): 817-819.  Full Text
    • Machline-Carrion, MJ, Santucci, EV, Damiani, LP, Bahit, MC, Málaga, G, Pontes-Neto, OM, Martins, SCO, Zétola, VF, Normilio-Silva, K, Rodrigues de Freitas, G, Gorgulho, A, De Salles, A, Pacheco da Silva, BG, Santos, JY, de Andrade Jesuíno, I, Bueno, PRT, Cavalcanti, AB, Guimarães, HP, Xian, Y, Bettger, JP, Lopes, RD, Peterson, ED, Berwanger, O, and BRIDGE-Stroke Investigators, . "Effect of a Quality Improvement Intervention on Adherence to Therapies for Patients With Acute Ischemic Stroke and Transient Ischemic Attack: A Cluster Randomized Clinical Trial." Jama Neurology (May 6, 2019).  Full Text
    • Guimarães, PO, Pokorney, SD, Lopes, RD, Wojdyla, DM, Gersh, BJ, Giczewska, A, Carnicelli, A, Lewis, BS, Hanna, M, Wallentin, L, Vinereanu, D, Alexander, JH, and Granger, CB. "Efficacy and safety of apixaban vs warfarin in patients with atrial fibrillation and prior bioprosthetic valve replacement or valve repair: Insights from the ARISTOTLE trial." Clinical Cardiology 42, no. 5 (May 2019): 568-571.  Full Text
    • Harskamp, RE, Granger, TM, Clare, RM, White, KR, Lopes, RD, Pieper, KS, Granger, CB, Newgard, CB, Shah, SH, and Newby, LK. "Peripheral blood metabolite profiles associated with new onset atrial fibrillation." American Heart Journal 211 (May 2019): 54-59.  Full Text
    • Spitzer, E, McFadden, E, Vranckx, P, Garcia-Garcia, HM, Seltzer, JH, Held, C, de Vries, T, Menon, V, Brown, KJ, Soliman, OII, Onuma, Y, Lopes, RD, Stone, GW, Cutlip, DE, and Serruys, PW. "Critical Appraisal of Contemporary Clinical Endpoint Definitions in Coronary Intervention Trials: A Guidance Document." Jacc. Cardiovascular Interventions 12, no. 9 (May 2019): 805-819. (Review)  Full Text
    • Guimarães, PO, Peterson, ED, Stevens, SR, Lokhnygina, Y, Green, JB, McGuire, DK, Holman, RR, and Lopes, RD. "Antithrombotic treatment gap among patients with atrial fibrillation and type 2 diabetes." International Journal of Cardiology (April 30, 2019).  Full Text
    • Guimarães, PO, Lopes, RD, Alexander, JH, Thomas, L, Hellkamp, AS, Hijazi, Z, Hylek, EM, Gersh, BJ, Garcia, DA, Verheugt, FWA, Hanna, M, Flaker, G, Vinereanu, D, and Granger, CB. "International normalized ratio control and subsequent clinical outcomes in patients with atrial fibrillation using warfarin." Journal of Thrombosis and Thrombolysis (April 10, 2019).  Full Text
    • Machline-Carrion, MJ, Soares, RM, Damiani, LP, Campos, VB, Sampaio, B, Fonseca, FH, Izar, MC, Amodeo, C, Pontes-Neto, OM, Santos, JY, Gomes, SPDC, Saraiva, JFK, Ramacciotti, E, Barros E Silva, PGDM, Lopes, RD, Brandão da Silva, N, Guimarães, HP, Piegas, L, Stein, AT, Berwanger, O, and BRIDGE Cardiovascular Prevention Investigators, . "Effect of a Multifaceted Quality Improvement Intervention on the Prescription of Evidence-Based Treatment in Patients at High Cardiovascular Risk in Brazil: The BRIDGE Cardiovascular Prevention Cluster Randomized Clinical Trial." Jama Cardiology (April 3, 2019).  Full Text
    • Lopes, RD, Heizer, G, Aronson, R, Vora, AN, Massaro, T, Mehran, R, Goodman, SG, Windecker, S, Darius, H, Li, J, Averkov, O, Bahit, MC, Berwanger, O, Budaj, A, Hijazi, Z, Parkhomenko, A, Sinnaeve, P, Storey, RF, Thiele, H, Vinereanu, D, Granger, CB, Alexander, JH, and AUGUSTUS Investigators, . "Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation." The New England Journal of Medicine 380, no. 16 (April 2019): 1509-1524.  Full Text
    • Washam, JB, Hohnloser, SH, Lopes, RD, Wojdyla, DM, Vinereanu, D, Alexander, JH, Gersh, BJ, Hanna, M, Horowitz, J, Hylek, EM, Xavier, D, Verheugt, FWA, Wallentin, L, Granger, CB, and ARISTOTLE Committees and Investigators, . "Interacting medication use and the treatment effects of apixaban versus warfarin: results from the ARISTOTLE Trial." Journal of Thrombosis and Thrombolysis 47, no. 3 (April 2019): 345-352.  Full Text
    • Fanaroff, AC, Califf, RM, Windecker, S, Smith, SC, and Lopes, RD. "Levels of Evidence Supporting American College of Cardiology/American Heart Association and European Society of Cardiology Guidelines, 2008-2018." Jama 321, no. 11 (March 2019): 1069-1080.  Full Text
    • Hochman, Judith S., Harmony R. Reynolds, Sripal Bangalore, Sean M. O’Brien, Karen P. Alexander, Roxy Senior, William E. Boden, et al. “Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial..” Jama Cardiology, February 27, 2019. https://doi.org/10.1001/jamacardio.2019.0014.
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    • Alexander, Karen P., Marc A. Brouwer, Hillary Mulder, Dragos Vinereanu, Renato D. Lopes, Marco Proietti, Sana M. Al-Khatib, et al. “Outcomes of apixaban versus warfarin in patients with atrial fibrillation and multi-morbidity: Insights from the ARISTOTLE trial..” American Heart Journal 208 (February 2019): 123–31. https://doi.org/10.1016/j.ahj.2018.09.017.
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    • Fanaroff, Alexander C., Robert Clare, Karen S. Pieper, Kenneth W. Mahaffey, Chiara Melloni, Jennifer B. Green, John H. Alexander, et al. “Frequency, Regional Variation, and Predictors of Undetermined Cause of Death in Cardiometabolic Clinical Trials: A Pooled Analysis of 9259 Deaths in 9 Trials..” Circulation 139, no. 7 (February 2019): 863–73. https://doi.org/10.1161/circulationaha.118.037202.
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    • Held, Claes, Harvey D. White, Ralph A. H. Stewart, Richard Davies, Shani Sampson, Karen Chiswell, Adam Silverstein, et al. “Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease: Insights from the STABILITY trial..” American Heart Journal 208 (February 2019): 65–73. https://doi.org/10.1016/j.ahj.2018.10.010.
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    • Ranney, David N., Judson B. Williams, Hillary Mulder, Daniel Wojdyla, Morgan L. Cox, C Michael Gibson, Michael J. Mack, Mani A. Daneshmand, John H. Alexander, and Renato D. Lopes. “Comparison of Outcomes and Frequency of Graft Failure With Use of Free Versus In Situ Internal Mammary Artery Bypass Conduits (from the PREVENT IV Trial)..” The American Journal of Cardiology 123, no. 4 (February 2019): 571–75. https://doi.org/10.1016/j.amjcard.2018.11.029.
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    • Van der Wall, Sake J., Renato D. Lopes, James Aisenberg, Paul Reilly, Joanne van Ryn, Stephan Glund, Amelie Elsaesser, Frederikus A. Klok, Charles V. Pollack, and Menno V. Huisman. “Idarucizumab for Dabigatran Reversal in the Management of Patients With Gastrointestinal Bleeding..” Circulation 139, no. 6 (February 2019): 748–56. https://doi.org/10.1161/circulationaha.118.036710.
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    • Christersson, C, Wallentin, L, Andersson, U, Alexander, JH, Alings, M, De Caterina, R, Gersh, BJ, Granger, CB, Halvorsen, S, Hanna, M, Huber, K, Hylek, EM, Lopes, RD, Oh, B-H, and Siegbahn, A. "Effect of apixaban compared with warfarin on coagulation markers in atrial fibrillation." Heart (British Cardiac Society) 105, no. 3 (February 2019): 235-242.  Full Text
    • Guimarães, Patrícia O., Pearl Zakroysky, Abhinav Goyal, Renato D. Lopes, Lisa A. Kaltenbach, and Tracy Y. Wang. “Usefulness of Antithrombotic Therapy in Patients With Atrial Fibrillation and Acute Myocardial Infarction..” The American Journal of Cardiology 123, no. 1 (January 2019): 12–18. https://doi.org/10.1016/j.amjcard.2018.09.031.
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    • Machline-Carrion, Maria Julia, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Pontes-Neto, Sheila Cristina Ouriques Martins, et al. “An international cluster-randomized quality improvement trial to increase the adherence to evidence-based therapies for acute ischemic stroke and transient ischemic attack patients: Rationale and design of the BRIDGE STROKE Trial..” American Heart Journal 207 (January 2019): 49–57. https://doi.org/10.1016/j.ahj.2018.09.009.
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    • Machline-Carrion, Maria Julia, Rafael Marques Soares, Lucas Petri Damiani, Viviane Bezerra Campos, Bruna Sampaio, Juliana Yamashita, Francisco H. Fonseca, et al. “Rationale and design for a cluster randomized quality-improvement trial to increase the uptake of evidence-based therapies for patients at high cardiovascular risk: The BRIDGE-Cardiovascular Prevention trial..” American Heart Journal 207 (January 2019): 40–48. https://doi.org/10.1016/j.ahj.2018.10.001.
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    • Vamos, Mate, Julia Wiebke Erath, Alexander Philipp Benz, Renato Delascio Lopes, and Stefan Hans Hohnloser. “Meta-Analysis of Effects of Digoxin on Survival in Patients with Atrial Fibrillation or Heart Failure: An Update..” The American Journal of Cardiology 123, no. 1 (January 2019): 69–74. https://doi.org/10.1016/j.amjcard.2018.09.036.
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    • Berger, Jeffrey S., Beth L. Abramson, Renato D. Lopes, Gretchen Heizer, Frank W. Rockhold, Iris Baumgartner, F Gerry R. Fowkes, et al. “Ticagrelor versus clopidogrel in patients with symptomatic peripheral artery disease and prior coronary artery disease: Insights from the EUCLID trial..” Vascular Medicine (London, England) 23, no. 6 (December 2018): 523–30. https://doi.org/10.1177/1358863x18775594.
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    • Fanaroff, Alexander C., Derek Cyr, Megan L. Neely, Jeffery Bakal, Harvey D. White, Keith A. A. Fox, Paul W. Armstrong, Renato D. Lopes, E Magnus Ohman, and Matthew T. Roe. “Days Alive and Out of Hospital: Exploring a Patient-Centered, Pragmatic Outcome in a Clinical Trial of Patients With Acute Coronary Syndromes..” Circulation. Cardiovascular Quality and Outcomes 11, no. 12 (December 2018). https://doi.org/10.1161/circoutcomes.118.004755.
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    • Low Wang, Cecilia C., Juuso I. Blomster, Gretchen Heizer, Jeffrey S. Berger, Iris Baumgartner, F Gerry R. Fowkes, Peter Held, et al. “Cardiovascular and Limb Outcomes in Patients With Diabetes and Peripheral Artery Disease: The EUCLID Trial..” Journal of the American College of Cardiology 72, no. 25 (December 2018): 3274–84. https://doi.org/10.1016/j.jacc.2018.09.078.
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    • Lopes, Renato D., Pedro G. M. de Barros E Silva, Isabella de Andrade Jesuíno, Eliana Vieira Santucci, Lilian Mazza Barbosa, Lucas Petri Damiani, Renato Hideo Nakagawa Santos, et al. “Timing of Loading Dose of Atorvastatin in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes: Insights From the SECURE-PCI Randomized Clinical Trial..” Jama Cardiology 3, no. 11 (November 2018): 1113–18. https://doi.org/10.1001/jamacardio.2018.3408.
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    • Olivier, Christoph B., Vandana Sundaram, Deepak L. Bhatt, Sergio Leonardi, Renato D. Lopes, Victoria Y. Ding, Lingyao Yang, et al. “Definitions of peri-procedural myocardial infarction and the association with one-year mortality: Insights from CHAMPION trials..” International Journal of Cardiology 270 (November 2018): 96–101. https://doi.org/10.1016/j.ijcard.2018.06.034.
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    • Sawhney, Jitendra Ps, Veerappa A. Kothiwale, Vikas Bisne, Rajashekhar Durgaprasad, Praveen Jadhav, Manoj Chopda, Velam Vanajakshamma, et al. “Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry..” Indian Heart Journal 70, no. 6 (November 2018): 828–35. https://doi.org/10.1016/j.ihj.2018.09.001.
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    • Hernandez, Adrian F., Jennifer B. Green, Salim Janmohamed, Ralph B. D’Agostino, Christopher B. Granger, Nigel P. Jones, Lawrence A. Leiter, et al. “Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial..” Lancet (London, England) 392, no. 10157 (October 2, 2018): 1519–29. https://doi.org/10.1016/s0140-6736(18)32261-x.
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    • Luo, Nancy, Haolin Xu, Hani Jneid, Gregg C. Fonarow, Renato D. Lopes, Jonathan P. Piccini, Anne B. Curtis, et al. “Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation..” Circulation. Heart Failure 11, no. 10 (October 2018). https://doi.org/10.1161/circheartfailure.118.005356.
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    • Sharma, Abhinav, Ziad Hijazi, Ulrika Andersson, Sana M. Al-Khatib, Renato D. Lopes, John H. Alexander, Claes Held, et al. “Use of Biomarkers to Predict Specific Causes of Death in Patients With Atrial Fibrillation..” Circulation 138, no. 16 (October 2018): 1666–76. https://doi.org/10.1161/circulationaha.118.034125.
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    • Mentz, RJ, Bethel, MA, Merrill, P, Lokhnygina, Y, Buse, JB, Chan, JC, Felício, JS, Goodman, SG, Choi, J, Gustavson, SM, Iqbal, N, Lopes, RD, Maggioni, AP, Öhman, P, Pagidipati, NJ, Poulter, NR, Ramachandran, A, Reicher, B, Holman, RR, Hernandez, AF, and EXSCEL Study Group, . "Effect of Once-Weekly Exenatide on Clinical Outcomes According to Baseline Risk in Patients With Type 2 Diabetes Mellitus: Insights From the EXSCEL Trial." Journal of the American Heart Association 7, no. 19 (October 2018): e009304-null.  Full Text
    • Nazha, B, Pandya, B, Cohen, J, Zhang, M, Lopes, RD, Garcia, DA, Sherwood, MW, and Spyropoulos, AC. "Periprocedural Outcomes of Direct Oral Anticoagulants Versus Warfarin in Nonvalvular Atrial Fibrillation." Circulation 138, no. 14 (October 2018): 1402-1411.  Full Text
    • Nicolau, JC, Furtado, RHM, Baracioli, LM, Lara, LM, Dalçóquio, TF, Scanavini Junior, MA, Pereira, CAC, Lima, VM, Gonçalves, TM, Colodetti, R, Ferrari, AG, Lopes, RD, and Giugliano, RP. "The Use of Oral Beta-Blockers and Clinical Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes: a Long-Term Follow-Up Study." Cardiovascular Drugs and Therapy 32, no. 5 (October 2018): 435-442.  Full Text
    • Barros E Silva, Pedro Gabriel Melo de, Henrique Barbosa Ribeiro, Renato Delascio Lopes, Thiago Andrade Macedo, Fabio Conejo, Antônio Cláudio do Amaral Baruzzi, Mariana Yumi Okada, et al. “Improvement in quality indicators using NCDR® registries: First international experience..” International Journal of Cardiology 267 (September 2018): 13–15. https://doi.org/10.1016/j.ijcard.2018.05.102.
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    • Lopes, Renato D., Jan Steffel, Manuela Di Fusco, Allison Keshishian, Xuemei Luo, Xiaoyan Li, Cristina Masseria, et al. “Effectiveness and Safety of Anticoagulants in Adults with Non-valvular Atrial Fibrillation and Concomitant Coronary/Peripheral Artery Disease..” The American Journal of Medicine 131, no. 9 (September 2018): 1075-1085.e4. https://doi.org/10.1016/j.amjmed.2018.05.007.
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    • Vora, Amit N., Dadi Dai, Roland Matsuoka, J Kevin Harrison, G Chad Hughes, Matthew W. Sherwood, Jonathan P. Piccini, et al. “Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry..” Jacc. Cardiovascular Interventions 11, no. 17 (September 2018): 1746–56. https://doi.org/10.1016/j.jcin.2018.05.042.
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    • Spyropoulos, AC, Ageno, W, Albers, GW, Elliott, CG, Halperin, JL, Hiatt, WR, Maynard, GA, Steg, PG, Weitz, JI, Suh, E, Spiro, TE, Barnathan, ES, Raskob, GE, and MARINER Investigators, . "Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness." The New England Journal of Medicine 379, no. 12 (September 2018): 1118-1127.  Full Text
    • Lopes, Renato D., Weimar Kunz Sebba Barroso, Andrea Araujo Brandao, Eduardo Costa Duarte Barbosa, Marcus Vinicius Bolivar Malachias, Marco Mota Gomes, Celso Amodeo, et al. “The First Brazilian Registry of Hypertension..” American Heart Journal, August 30, 2018. https://doi.org/10.1016/j.ahj.2018.08.012.
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    • Capodanno, Davide, Roxana Mehran, Marco Valgimigli, Usman Baber, Stephan Windecker, Pascal Vranckx, George Dangas, et al. “Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention..” Nature Reviews. Cardiology 15, no. 8 (August 2018): 480–96. https://doi.org/10.1038/s41569-018-0049-1.
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    • Fanaroff, Alexander C., Jan Steffel, John H. Alexander, Gregory Y. H. Lip, Robert M. Califf, and Renato D. Lopes. “Stroke prevention in atrial fibrillation: re-defining 'real-world data' within the broader data universe..” European Heart Journal 39, no. 32 (August 2018): 2932–41. https://doi.org/10.1093/eurheartj/ehy236.
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    • Horowitz, John D., Raffaele De Caterina, Tamila Heresztyn, John H. Alexander, Ulrika Andersson, Renato D. Lopes, Philippe Gabriel Steg, et al. “Asymmetric and Symmetric Dimethylarginine Predict Outcomes in Patients With Atrial Fibrillation: An ARISTOTLE Substudy..” Journal of the American College of Cardiology 72, no. 7 (August 2018): 721–33. https://doi.org/10.1016/j.jacc.2018.05.058.
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    • Vinereanu, Dragos, Alice Wang, Hillary Mulder, Renato D. Lopes, Petr Jansky, Basil S. Lewis, Bernard J. Gersh, et al. “Outcomes in anticoagulated patients with atrial fibrillation and with mitral or aortic valve disease..” Heart (British Cardiac Society) 104, no. 15 (August 2018): 1292–99. https://doi.org/10.1136/heartjnl-2017-312272.
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    • Berwanger, O, Nicolau, JC, Carvalho, AC, Jiang, L, Goodman, S, Nicholls, SJ, Parkhomenko, A, Averkov, O, Tajer, C, Malaga, G, Kerr Saraiva, JF, Fonseca, F, Guimaraes, HP, de Barros E Silva, PGM, Damiani, LP, Paisani, DM, Lasagno, CMR, Candido, CT, Valeis, N, Moia, DDF, Piegas, LS, Granger, CB, White, H, and Lopes, RD. "Ticagrelor versus clopidogrel after fibrinolytic therapy in patients with ST-elevation myocardial infarction: Rationale and design of the ticagrelor in patients with ST elevation myocardial infarction treated with thrombolysis (TREAT) trial." American Heart Journal 202 (August 2018): 89-96.  Full Text
    • van Diepen, S, Tran, DT, Ezekowitz, JA, Zygun, DA, Katz, JN, Lopes, RD, Newby, LK, McAlister, FA, and Kaul, P. "The high cost of critical care unit over-utilization for patients with NSTE ACS." American Heart Journal 202 (August 2018): 84-88.  Full Text
    • Filgueiras Filho, Nivaldo Menezes, Gilson Soares Feitosa Filho, Davi Jorge Fontoura Solla, Felipe Coelho Argôlo, Patrícia Oliveira Guimarães, Ivan de Mattos Paiva Filho, Larissa Gordilho Mutti Carvalho, et al. “Implementation of a Regional Network for ST-Segment-Elevation Myocardial Infarction (STEMI) Care and 30-Day Mortality in a Low- to Middle-Income City in Brazil: Findings From Salvador's STEMI Registry (RESISST)..” Journal of the American Heart Association 7, no. 14 (July 6, 2018). https://doi.org/10.1161/JAHA.118.008624.
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    • Lehman, E Philip, Patricia A. Cowper, Tiffany C. Randolph, Andrzej S. Kosinski, Renato D. Lopes, and Pamela S. Douglas. “Usefulness and Cost-Effectiveness of Universal Echocardiographic Contrast to Detect Left Ventricular Thrombus in Patients with Heart Failure and Reduced Ejection Fraction..” The American Journal of Cardiology 122, no. 1 (July 2018): 121–28. https://doi.org/10.1016/j.amjcard.2018.03.016.
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    • Lopes, Renato D., Roberto Rordorf, Gaetano M. De Ferrari, Sergio Leonardi, and Lars Wallentin. “Reply: Digoxin Use in Atrial Fibrillation: Minimizing and Refining its Use When Still Needed..” Journal of the American College of Cardiology 72, no. 1 (July 2018): 125–26. https://doi.org/10.1016/j.jacc.2018.04.045.
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    • Inohara, T, Pieper, K, Wojdyla, DM, Patel, MR, Jones, WS, Tricoci, P, Mahaffey, KW, James, SK, Alexander, JH, Lopes, RD, Wallentin, L, Ohman, EM, Roe, MT, and Vemulapalli, S. "Incidence, timing, and type of first and recurrent ischemic events in patients with and without peripheral artery disease after an acute coronary syndrome." American Heart Journal 201 (July 2018): 25-32.  Full Text
    • Rymer, JA, Tempelhof, MW, Clare, RM, Pieper, KS, Granger, CB, Van de Werf, F, Moliterno, DJ, Harrington, RA, White, HD, Armstrong, PW, Lopes, RD, Mahaffey, KW, and Newby, LK. "Discharge timing and outcomes after uncomplicated non-ST-segment elevation acute myocardial infarction." American Heart Journal 201 (July 2018): 103-110.  Full Text
    • Roever, Leonardo, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, et al. “High-density lipoprotein-cholesterol functionality and metabolic syndrome: Protocol for review and meta-analysis..” Medicine 97, no. 24 (June 2018). https://doi.org/10.1097/MD.0000000000011094.
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    • Sposato, Luciano A., and Renato D. Lopes. “Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice..” International Journal of Cardiology 261 (June 2018): 99–100. https://doi.org/10.1016/j.ijcard.2017.12.008.
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    • Lopes, RD, Vora, AN, Liaw, D, Granger, CB, Darius, H, Goodman, SG, Mehran, R, Windecker, S, and Alexander, JH. "An open-Label, 2 × 2 factorial, randomized controlled trial to evaluate the safety of apixaban vs. vitamin K antagonist and aspirin vs. placebo in patients with atrial fibrillation and acute coronary syndrome and/or percutaneous coronary intervention: Rationale and design of the AUGUSTUS trial." American Heart Journal 200 (June 2018): 17-23.  Full Text
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    • Paquet, Maryse, Joshua O. Cerasuolo, Victoria Thorburn, Sebastian Fridman, Rasha Alsubaie, Renato D. Lopes, Lauren E. Cipriano, et al. “Pathophysiology and Risk of Atrial Fibrillation Detected after Ischemic Stroke (PARADISE): A Translational, Integrated, and Transdisciplinary Approach..” Journal of Stroke and Cerebrovascular Diseases : The Official Journal of National Stroke Association 27, no. 3 (March 2018): 606–19. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.038.
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    • Sherwood, Matthew W., Renato D. Lopes, Jie Lena Sun, Danny Liaw, Robert A. Harrington, Lars Wallentin, Daniel T. Laskowitz, et al. “Apixaban following acute coronary syndromes in patients with prior stroke: Insights from the APPRAISE-2 trial..” American Heart Journal 197 (March 2018): 1–8. https://doi.org/10.1016/j.ahj.2017.09.020.
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    • Sposato, Luciano A., Sebastian Fridman, Shawn N. Whitehead, and Renato D. Lopes. “Linking stroke-induced heart injury and neurogenic atrial fibrillation: a hypothesis to be proven..” Journal of Electrocardiology, February 20, 2018. https://doi.org/10.1016/j.jelectrocard.2018.02.006.
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    • Vaduganathan, M, Harrington, RA, Stone, GW, Steg, G, Gibson, CM, Hamm, CW, Price, MJ, Lopes, RD, Leonardi, S, Deliargyris, EN, Prats, J, Mahaffey, KW, White, HD, and Bhatt, DL. "Short- and long-term mortality following bleeding events in patients undergoing percutaneous coronary intervention: insights from four validated bleeding scales in the CHAMPION trials." Eurointervention : Journal of Europcr in Collaboration With the Working Group on Interventional Cardiology of the European Society of Cardiology 13, no. 15 (February 2, 2018): e1841-e1849.  Full Text
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    • Sposato, Luciano A., and Renato D. Lopes. “Oral anticoagulation: a step toward solving the puzzle of dementia related to atrial fibrillation?.” European Heart Journal 39, no. 6 (February 2018): 461–63. https://doi.org/10.1093/eurheartj/ehx649.
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    • Sandhu, Roopinder K., Justin A. Ezekowitz, Ziad Hijazi, Johan Westerbergh, Julia Aulin, John H. Alexander, Christopher B. Granger, et al. “Obesity paradox on outcome in atrial fibrillation maintained even considering the prognostic influence of biomarkers: insights from the ARISTOTLE trial..” Open Heart 5, no. 2 (January 2018). https://doi.org/10.1136/openhrt-2018-000908.
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    • Sharma, Abhinav, Jennifer B. Green, Allison Dunning, Yuliya Lokhnygina, Sana M. Al-Khatib, Renato D. Lopes, John B. Buse, et al. “Causes of Death in a Contemporary Cohort of Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: Insights From the TECOS Trial..” Diabetes Care 40, no. 12 (December 2017): 1763–70. https://doi.org/10.2337/dc17-1091.
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    • Vinereanu, Dragos, Renato D. Lopes, Hillary Mulder, Bernard J. Gersh, Michael Hanna, Pedro G. M. de Barros E Silva, Dan Atar, et al. “Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin..” Stroke 48, no. 12 (December 2017): 3266–73. https://doi.org/10.1161/strokeaha.117.017574.
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    • Williams, Judson B., Eric D. Peterson, Álvaro S. Albrecht, Shuang Li, Sameer A. Hirji, T. Ferguson, Peter K. Smith, and Renato D. Lopes. “Glycemic control in patients undergoing coronary artery bypass graft surgery: Clinical features, predictors, and outcomes..” Journal of Critical Care 42 (December 2017): 328–33. https://doi.org/10.1016/j.jcrc.2017.09.013.
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    • Lopes, Renato D., Patricia O. Guimarães, Elaine Hylek, Gilson S. Feitosa-Filho, Luiz Ritt, Nivaldo Filgueiras, Eduardo Darzé, et al. “Highlights from the Ninth International Symposium of Thrombosis and Anticoagulation (ISTA IX), October 15, 2016, Salvador, Bahia, Brazil..” Journal of Thrombosis and Thrombolysis 44, no. 4 (November 2017): 544–55. https://doi.org/10.1007/s11239-017-1551-8.
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    • Kittle, Jessie, Renato D. Lopes, Mingyan Huang, Marsha L. Marquess, Matthew D. Wilson, John Ascher, Alok Krishen, et al. “Cardiovascular adverse events in the drug-development program of bupropion for smoking cessation: A systematic retrospective adjudication effort..” Clinical Cardiology 40, no. 10 (October 2017): 899–906. https://doi.org/10.1002/clc.22744.
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    • Koshizaka, Masaya, Renato D. Lopes, L Kristin Newby, Robert M. Clare, Phillip J. Schulte, Pierluigi Tricoci, Kenneth W. Mahaffey, et al. “Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites..” The American Journal of Medicine 130, no. 10 (October 2017): 1170–76. https://doi.org/10.1016/j.amjmed.2017.03.030.
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    • Vinereanu, Dragos, Hussein R. Al-Khalidi, Meena P. Rao, Wensheng He, Renato D. Lopes, Cecilia M. Bahit, Andrea O. Ciobanu, et al. “Regional differences in presentation and antithrombotic treatment of patients with atrial fibrillation: Baseline characteristics from a clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with atrial fibrillation (IMPACT-AF)..” American Heart Journal 192 (October 2017): 38–47. https://doi.org/10.1016/j.ahj.2017.07.004.
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    • Hess, Paul L., Hussein R. Al-Khalidi, Daniel J. Friedman, Hillary Mulder, Anna Kucharska-Newton, Wayne R. Rosamond, Renato D. Lopes, et al. “The Metabolic Syndrome and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study..” Journal of the American Heart Association 6, no. 8 (August 23, 2017). https://doi.org/10.1161/JAHA.117.006103.
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    • Vora, Amit N., Tracy Y. Wang, Shuang Li, Karen Chiswell, Connie Hess, Renato D. Lopes, Sunil V. Rao, and Eric D. Peterson. “Selection of Stent Type in Patients With Atrial Fibrillation Presenting With Acute Myocardial Infarction: An Analysis From the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines..” Journal of the American Heart Association 6, no. 8 (August 21, 2017). https://doi.org/10.1161/JAHA.116.005280.
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    • Gibson, C Michael, Serge Korjian, Gerald Chi, Yazan Daaboul, Purva Jain, Douglas Arbetter, Samuel Z. Goldhaber, et al. “Comparison of Fatal or Irreversible Events With Extended-Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy..” Journal of the American Heart Association 6, no. 7 (July 11, 2017). https://doi.org/10.1161/JAHA.117.006015.
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    • Boonyawat, K., F. Caron, A. Li, C. Chai-Adisaksopha, W. Lim, A. Iorio, R. D. Lopes, D. Garcia, and M. A. Crowther. “Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and meta-analysis..” Journal of Thrombosis and Haemostasis : Jth 15, no. 7 (July 2017): 1322–33. https://doi.org/10.1111/jth.13701.
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    • Lopes, Renato D., Marco Alings, Stuart J. Connolly, Heather Beresh, Christopher B. Granger, Juan Benezet Mazuecos, Giuseppe Boriani, et al. “Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial..” American Heart Journal 189 (July 2017): 137–45. https://doi.org/10.1016/j.ahj.2017.04.008.
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    • Manning, Michael W., Mary Cooter, Joseph Mathew, John Alexander, Eric Peterson, T Bruce Ferguson, Renato Lopes, and Mihai Podgoreanu. “Angiotensin Receptor Blockade Improves Cardiac Surgical Outcomes in Patients With Metabolic Syndrome..” The Annals of Thoracic Surgery 104, no. 1 (July 2017): 98–105. https://doi.org/10.1016/j.athoracsur.2016.10.021.
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    • Suzumura, Erica Aranha, Rodrigo Antonini Ribeiro, Leticia Kawano-Dourado, Pedro Gabriel de Barros E Silva, Claudia Oliveira, Mabel Fernandes Figueiró, Alexandre Biasi Cavalcanti, Renato D. Lopes, and Otavio Berwanger. “Effects of perioperative statin use on cardiovascular complications in patients submitted to non-cardiac surgery: protocol for a systematic review, meta-analysis, and trial sequential analysis..” Systematic Reviews 6, no. 1 (June 19, 2017). https://doi.org/10.1186/s13643-017-0500-0.
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    • Guimarães, Patrícia O., Renato D. Lopes, Daniel M. Wojdyla, Azmil H. Abdul-Rahim, Stuart J. Connolly, Greg C. Flaker, Junyuan Wang, et al. “Effect of Apixaban on All-Cause Death in Patients with Atrial Fibrillation: a Meta-Analysis Based on Imputed Placebo Effect..” Cardiovascular Drugs and Therapy 31, no. 3 (June 2017): 295–301. https://doi.org/10.1007/s10557-017-6728-z.
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    • Lopes, Renato D., Patrícia O. Guimarães, Bradley J. Kolls, Daniel M. Wojdyla, Cheryl D. Bushnell, Michael Hanna, J Donald Easton, et al. “Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy..” Blood 129, no. 22 (June 2017): 2980–87. https://doi.org/10.1182/blood-2016-08-731638.
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    • Cowper, Patricia A., Shubin Sheng, Renato D. Lopes, Kevin J. Anstrom, Judith A. Stafford, Linda Davidson-Ray, Sana M. Al-Khatib, et al. “Economic Analysis of Apixaban Therapy for Patients With Atrial Fibrillation From a US Perspective: Results From the ARISTOTLE Randomized Clinical Trial..” Jama Cardiology 2, no. 5 (May 2017): 525–34. https://doi.org/10.1001/jamacardio.2017.0065.
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    • Diepen, Sean van, Peter D. Merrill, Michel Carrier, Jean-Claude Tardif, Mihai Podgoreanu, John H. Alexander, and Renato D. Lopes. “Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery..” Journal of Thrombosis and Thrombolysis 43, no. 4 (May 2017): 446–53. https://doi.org/10.1007/s11239-017-1480-6.
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    • Vora, Amit N., John H. Alexander, and Renato D. Lopes. “Dabigatran Compared With Rivaroxaban vs Warfarin..” Jama Internal Medicine 177, no. 5 (May 2017): 742–43. https://doi.org/10.1001/jamainternmed.2017.0561.
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    • Hess, CN, Clare, RM, Neely, ML, Tricoci, P, Mahaffey, KW, James, SK, Alexander, JH, Held, C, Lopes, RD, Fox, KAA, White, HD, Wallentin, L, Armstrong, PW, Harrington, RA, Ohman, EM, and Roe, MT. "Differential occurrence, profile, and impact of first recurrent cardiovascular events after an acute coronary syndrome." American Heart Journal 187 (May 2017): 194-203.  Full Text
    • Guimarães, Patrícia O., Renato D. Lopes, Susanna R. Stevens, André Zimerman, Lisa Wruck, Stefan K. James, Ghazala Haque, Roberto Rocha C. V. Giraldez, John H. Alexander, and Karen P. Alexander. “Reporting Clinical End Points and Safety Events in an Acute Coronary Syndrome Trial: Results With Integrated Collection..” Journal of the American Heart Association 6, no. 4 (April 24, 2017). https://doi.org/10.1161/JAHA.117.005490.
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    • Bahit, M Cecilia, Renato D. Lopes, Daniel M. Wojdyla, Claes Held, Michael Hanna, Dragos Vinereanu, Elaine M. Hylek, et al. “Non-major bleeding with apixaban versus warfarin in patients with atrial fibrillation..” Heart (British Cardiac Society) 103, no. 8 (April 2017): 623–28. https://doi.org/10.1136/heartjnl-2016-309901.
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    • Ducrocq, Gregory, Phillip J. Schulte, Andrzej Budaj, Jan H. Cornel, Claes Held, Anders Himmelmann, Steen Husted, et al. “Balancing the risk of spontaneous ischemic and major bleeding events in acute coronary syndromes..” American Heart Journal 186 (April 2017): 91–99. https://doi.org/10.1016/j.ahj.2017.01.010.
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    • Sharma, Abhinav, Flávio de Souza Brito, Jie-Lena Sun, Laine Thomas, Steven Haffner, Rury R. Holman, and Renato D. Lopes. “Noncardiovascular deaths are more common than cardiovascular deaths in patients with cardiovascular disease or cardiovascular risk factors and impaired glucose tolerance: Insights from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial..” American Heart Journal 186 (April 2017): 73–82. https://doi.org/10.1016/j.ahj.2016.12.011.
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    • Souza Brito, Flávio de, Rajendra H. Mehta, Renato D. Lopes, Ralf E. Harskamp, B Daniel Lucas, Phillip J. Schulte, Jean-Claude Tardif, and John H. Alexander. “Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery..” The American Journal of Medicine 130, no. 4 (April 2017): 462–68. https://doi.org/10.1016/j.amjmed.2016.10.023.
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    • Hess, Paul L., Jeff S. Healey, Christopher B. Granger, Stuart J. Connolly, Paul D. Ziegler, John H. Alexander, Peter R. Kowey, et al. “The Role of Cardiovascular Implantable Electronic Devices in the Detection and Treatment of Subclinical Atrial Fibrillation: A Review..” Jama Cardiology 2, no. 3 (March 2017): 324–31. https://doi.org/10.1001/jamacardio.2016.5167.
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    • Westenbrink, B Daan, Marco Alings, Christopher B. Granger, John H. Alexander, Renato D. Lopes, Elaine M. Hylek, Laine Thomas, et al. “Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial..” American Heart Journal 185 (March 2017): 140–49. https://doi.org/10.1016/j.ahj.2016.12.008.
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    • Armstrong, Paul W., Yinggan Zheng, Cynthia M. Westerhout, Fernado Rosell-Ortiz, Peter Sinnaeve, Yves Lambert, Renato D. Lopes, et al. “Corrigendum to "Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the Strategic Reperfusion Early After Myocardial infarction trial" [Am Heart J 169/6 (2015) 890-898]..” American Heart Journal 184 (February 2017). https://doi.org/10.1016/j.ahj.2017.01.005.
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    • Berwanger, Otavio, Pedro G. M. de Barros E Silva, Roberto Ramos Barbosa, Dalton Bertolim Precoma, Estêvão Lanna Figueiredo, Ludhmila Abrahão Hajjar, Cleber Dario Pinto Kruel, et al. “Atorvastatin for high-risk statin-naïve patients undergoing noncardiac surgery: The Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose (LOAD) randomized trial..” American Heart Journal 184 (February 2017): 88–96. https://doi.org/10.1016/j.ahj.2016.11.001.
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    • Tallo, FS, de Campos Vieira Abib, S, de Andrade Negri, AJ, Cesar, P, Lopes, RD, and Lopes, AC. "Evaluation of self-perception of mechanical ventilation knowledge among Brazilian final-year medical students, residents and emergency physicians." Clinics 72, no. 2 (February 2017): 65-70.  Full Text
    • Hu, Peter T., Renato D. Lopes, Susanna R. Stevens, Lars Wallentin, Laine Thomas, John H. Alexander, Michael Hanna, et al. “Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and Peripheral Artery Disease: Insights From the ARISTOTLE Trial..” Journal of the American Heart Association 6, no. 1 (January 17, 2017). https://doi.org/10.1161/JAHA.116.004699.
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    • Harumi Higuchi Dos Santos, Marilia, Abhinav Sharma, Jie-Lena Sun, Karen Pieper, John J. V. McMurray, Rury R. Holman, and Renato D. Lopes. “International Variation in Outcomes Among People with Cardiovascular Disease or Cardiovascular Risk Factors and Impaired Glucose Tolerance: Insights from the NAVIGATOR Trial..” Journal of the American Heart Association 6, no. 1 (January 13, 2017). https://doi.org/10.1161/JAHA.116.003892.
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    • Guimarães, Patrícia O., Daniel M. Wojdyla, John H. Alexander, Laine Thomas, Marco Alings, Greg C. Flaker, Sana M. Al-Khatib, et al. “Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial..” International Journal of Cardiology 227 (January 2017): 443–49. https://doi.org/10.1016/j.ijcard.2016.11.014.
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    • Dupre, Matthew E., and Renato D. Lopes. “Marital History and Survival After Stroke..” Journal of the American Heart Association 5, no. 12 (December 14, 2016). https://doi.org/10.1161/JAHA.116.004647.
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    • Katz, Marcelo, Hayden B. Bosworth, Renato D. Lopes, Matthew E. Dupre, Fernando Morita, Carolina Pereira, Fabio G. M. Franco, Rogerio R. Prado, Antonio E. Pesaro, and Mauricio Wajngarten. “A time-series analysis of the relation between unemployment rate and hospital admission for acute myocardial infarction and stroke in Brazil over more than a decade..” International Journal of Cardiology 224 (December 2016): 33–36. https://doi.org/10.1016/j.ijcard.2016.08.309.
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    • Li, Guowei, Lehana Thabane, Deborah J. Cook, Renato D. Lopes, John C. Marshall, Gordon Guyatt, Anne Holbrook, et al. “Risk factors for and prediction of mortality in critically ill medical-surgical patients receiving heparin thromboprophylaxis..” Annals of Intensive Care 6, no. 1 (December 2016). https://doi.org/10.1186/s13613-016-0116-x.
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    • Cornel, JH, Bakris, GL, Stevens, SR, Alvarsson, M, Bax, WA, Chuang, L-M, Engel, SS, Lopes, RD, McGuire, DK, Riefflin, A, Rodbard, HW, Sinay, I, Tankova, T, Wainstein, J, Peterson, ED, Holman, RR, and TECOS Study Group, . "Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOS." Diabetes Care 39, no. 12 (December 2016): 2304-2310.  Full Text
    • Gomes, Walter J., João Carlos Leal, Domingo M. Braile, Jorge A. Guimarães, Renato D. Lopes, Marcelo A. Lima, and Helena B. Nader. “A Brazilian perspective for the use of bovine heparin in open heart surgery..” International Journal of Cardiology 223 (November 2016): 611–12. https://doi.org/10.1016/j.ijcard.2016.08.033.
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    • Oldgren, Jonas, Ziad Hijazi, Johan Lindbäck, John H. Alexander, Stuart J. Connolly, John W. Eikelboom, Michael D. Ezekowitz, et al. “Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation..” Circulation 134, no. 22 (November 2016): 1697–1707. https://doi.org/10.1161/circulationaha.116.022802.
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    • Piccaro de Oliveira, Pedro, Vinicius Gonzales, Renato D. Lopes, Marcia Moura Schmidt, Silvia Garofallo, Rodrigo Pires Dos Santos, Luciana Carrion, Carlos Gottschall, and Alexandre S. Quadros. “Serious infections among unselected patients with ST-elevation myocardial infarction treated with contemporary primary percutaneous coronary intervention..” American Heart Journal 181 (November 2016): 52–59. https://doi.org/10.1016/j.ahj.2016.08.005.
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    • Li, Guowei, Deborah J. Cook, Lehana Thabane, Jan O. Friedrich, Tim M. Crozier, John Muscedere, John Granton, et al. “Erratum to: Risk factors for mortality in patients admitted to intensive care units with pneumonia..” Respiratory Research 17, no. 1 (October 7, 2016). https://doi.org/10.1186/s12931-016-0444-2.
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    • Li, Ang, Renato D. Lopes, and David A. Garcia. “Use of Direct Oral Anticoagulants in Special Populations..” Hematology/Oncology Clinics of North America 30, no. 5 (October 2016): 1053–71. https://doi.org/10.1016/j.hoc.2016.05.003.
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    • Sandhu, RK, Ezekowitz, J, Andersson, U, Alexander, JH, Granger, CB, Halvorsen, S, Hanna, M, Hijazi, Z, Jansky, P, Lopes, RD, and Wallentin, L. "The 'obesity paradox' in atrial fibrillation: observations from the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) trial." European Heart Journal 37, no. 38 (October 2016): 2869-2878.  Full Text
    • Alexander, John H., Ulrika Andersson, Renato D. Lopes, Ziad Hijazi, Stefan H. Hohnloser, Justin A. Ezekowitz, Sigrun Halvorsen, et al. “Apixaban 5 mg Twice Daily and Clinical Outcomes in Patients With Atrial Fibrillation and Advanced Age, Low Body Weight, or High Creatinine: A Secondary Analysis of a Randomized Clinical Trial..” Jama Cardiology 1, no. 6 (September 2016): 673–81. https://doi.org/10.1001/jamacardio.2016.1829.
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    • Jackson, Larry R., Jonathan P. Piccini, Derek D. Cyr, Matthew T. Roe, Megan L. Neely, Felipe Martinez, Thomas F. Lüscher, et al. “Dual Antiplatelet Therapy and Outcomes in Patients With Atrial Fibrillation and Acute Coronary Syndromes Managed Medically Without Revascularization: Insights From the TRILOGY ACS Trial..” Clinical Cardiology 39, no. 9 (September 2016): 497–506. https://doi.org/10.1002/clc.22562.
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    • Armaganijan, Luciana V., Karen P. Alexander, Zhen Huang, Pierluigi Tricoci, Claes Held, Frans Van de Werf, Paul W. Armstrong, et al. “Effect of age on efficacy and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial..” American Heart Journal 178 (August 2016): 176–84. https://doi.org/10.1016/j.ahj.2016.05.012.
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    • Fitzmaurice, David A., Gabriele Accetta, Sylvia Haas, Gloria Kayani, Hector Lucas Luciardi, Frank Misselwitz, Karen Pieper, et al. “Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists..” British Journal of Haematology 174, no. 4 (August 2016): 610–23. https://doi.org/10.1111/bjh.14084.
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    • Hess, Paul L., Renato D. Lopes, and Jeff S. Healey. “Letter by Hess et al Regarding Article, "How to Manage Occult Atrial Fibrillation Detected on Long-Term Monitoring"..” Circulation 134, no. 5 (August 2016): e28–29. https://doi.org/10.1161/circulationaha.116.023088.
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    • Jardim, Paulo César Brandão Veiga, Weimar Kunz Sebba Barroso de Souza, Renato Delascio Lopes, Andréa Araújo Brandão, Marcus V Bolívar Malachias, Marco Mota Gomes, Heitor Moreno Júnior, Eduardo Costa Duarte Barbosa, and Rui Manoel Dos Santos Póvoa. “I RBH - First Brazilian Hypertension Registry..” Arquivos Brasileiros De Cardiologia 107, no. 2 (August 2016): 93–98. https://doi.org/10.5935/abc.20160120.
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    • Li, Guowei, Deborah J. Cook, Lehana Thabane, Jan O. Friedrich, Tim M. Crozier, John Muscedere, John Granton, et al. “Risk factors for mortality in patients admitted to intensive care units with pneumonia..” Respiratory Research 17, no. 1 (July 11, 2016). https://doi.org/10.1186/s12931-016-0397-5.
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    • Hijazi, Ziad, Stefan H. Hohnloser, Ulrika Andersson, John H. Alexander, Michael Hanna, Matyas Keltai, Alexander Parkhomenko, et al. “Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time: Insights From the ARISTOTLE Randomized Clinical Trial..” Jama Cardiology 1, no. 4 (July 2016): 451–60. https://doi.org/10.1001/jamacardio.2016.1170.
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    • Shimada, Yuichi J., Sameer Bansilal, Stephen D. Wiviott, Richard C. Becker, Robert A. Harrington, Anders Himmelmann, Benjamin Neely, et al. “Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial..” American Heart Journal 177 (July 2016): 1–8. https://doi.org/10.1016/j.ahj.2016.03.015.
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    • Lopes, Renato D., Karen S. Pieper, Susanna R. Stevens, Scott D. Solomon, John J. V. McMurray, Marc A. Pfeffer, Jeffrey D. Leimberger, and Eric J. Velazquez. “Predicting Outcomes Over Time in Patients With Heart Failure, Left Ventricular Systolic Dysfunction, or Both Following Acute Myocardial Infarction..” Journal of the American Heart Association 5, no. 6 (June 27, 2016). https://doi.org/10.1161/JAHA.115.003045.
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    • Jaspers Focks, Jeroen, Marc A. Brouwer, Daniel M. Wojdyla, Laine Thomas, Renato D. Lopes, Jeffrey B. Washam, Fernando Lanas, et al. “Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial..” Bmj (Clinical Research Ed.) 353 (June 15, 2016). https://doi.org/10.1136/bmj.i2868.
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    • Bahit, M Cecilia, Mariano L. Coppola, Patricia M. Riccio, Lauren E. Cipriano, Gregory A. Roth, Renato D. Lopes, Valery L. Feigin, et al. “First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina..” Stroke 47, no. 6 (June 2016): 1640–42. https://doi.org/10.1161/strokeaha.116.013637.
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    • Hijazi, Ziad, Jonas Oldgren, Johan Lindbäck, John H. Alexander, Stuart J. Connolly, John W. Eikelboom, Michael D. Ezekowitz, et al. “The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study..” Lancet (London, England) 387, no. 10035 (June 2016): 2302–11. https://doi.org/10.1016/s0140-6736(16)00741-8.
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    • Lopes, Renato D., Angelo Amato Vicenzo de Paola, Adalberto Menezes Lorga Filho, Fernanda Marciano Consolim-Colombo, Jadelson Andrade, Luiz Alberto Piva E Mattos, Sabrina Bernardez-Pereira, Otávio Berwanger, Marcio Jansen de Oliveira Figueiredo, and Marcio Jansen RECALL Steering Committee and Investigators. “Rationale and design of the First Brazilian Cardiovascular Registry of Atrial Fibrillation: The RECALL study..” American Heart Journal 176 (June 2016): 10–16. https://doi.org/10.1016/j.ahj.2016.03.001.
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    • Lopes, Renato D., Meena Rao, DaJuanicia N. Simon, Laine Thomas, Jack Ansell, Gregg C. Fonarow, Bernard J. Gersh, et al. “Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease..” The American Journal of Medicine 129, no. 6 (June 2016): 592-599.e1. https://doi.org/10.1016/j.amjmed.2015.12.026.
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    • Rao, Meena P., Andrea O. Ciobanu, Renato D. Lopes, Kathleen A. Fox, Ying Xian, Sean D. Pokorney, Hussein R. Al-Khalidi, et al. “A clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AF): design and rationale..” American Heart Journal 176 (June 2016): 107–13. https://doi.org/10.1016/j.ahj.2016.03.011.
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    • De Caterina, Raffaele, Ulrika Andersson, John H. Alexander, Sana M. Al-Khatib, M Cecilia Bahit, Shinya Goto, Michael Hanna, et al. “History of bleeding and outcomes with apixaban versus warfarin in patients with atrial fibrillation in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial..” American Heart Journal 175 (May 2016): 175–83. https://doi.org/10.1016/j.ahj.2016.01.005.
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    • Harskamp, Ralf E., John H. Alexander, T Bruce Ferguson, Rebecca Hager, Michael J. Mack, Brian Englum, Daniel Wojdyla, et al. “Response to Letters Regarding Article, "Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial"..” Circulation 133, no. 21 (May 2016). https://doi.org/10.1161/circulationaha.116.022510.
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    • McGuire, Darren K., Frans Van de Werf, Paul W. Armstrong, Eberhard Standl, Joerg Koglin, Jennifer B. Green, M Angelyn Bethel, et al. “Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial..” Jama Cardiology 1, no. 2 (May 2016): 126–35. https://doi.org/10.1001/jamacardio.2016.0103.
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    • Ruff, Christian T., Jack E. Ansell, Richard C. Becker, Emelia J. Benjamin, David J. Deicicchi, N. A. Mark Estes, Michael D. Ezekowitz, et al. “North American Thrombosis Forum, AF Action Initiative Consensus Document..” The American Journal of Medicine 129, no. 5 Suppl (May 2016): S1–29. https://doi.org/10.1016/j.amjmed.2016.02.001.
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    • Hijazi, Z, Lindbäck, J, Alexander, JH, Hanna, M, Held, C, Hylek, EM, Lopes, RD, Oldgren, J, Siegbahn, A, Stewart, RAH, White, HD, Granger, CB, Wallentin, L, and ARISTOTLE and STABILITY Investigators, . "The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation." European Heart Journal 37, no. 20 (May 2016): 1582-1590.  Full Text
    • Kragholm, Kristian, Sarah A. Goldstein, Qinghong Yang, Renato D. Lopes, Phillip J. Schulte, Gwen M. Bernacki, Harvey D. White, et al. “Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials.” Circulation 133, no. 16 (April 19, 2016): 1560-+. https://doi.org/10.1161/CIRCULATIONAHA.115.017299.
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    • Hijazi, Ziad, Julia Aulin, Ulrika Andersson, John H. Alexander, Bernard Gersh, Christopher B. Granger, Michael Hanna, et al. “Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation..” Heart (British Cardiac Society) 102, no. 7 (April 2016): 508–17. https://doi.org/10.1136/heartjnl-2015-308887.
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    • Kragholm, Kristian, Sarah A. Goldstein, Qinghong Yang, Renato D. Lopes, Phillip J. Schulte, Gwen M. Bernacki, Harvey D. White, et al. “Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials..” Circulation 133, no. 16 (April 2016): 1560–73. https://doi.org/10.1161/CIRCULATIONAHA.115.017299.
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    • Prates, Paulo Roberto L., Judson B. Williams, Rajendra H. Mehta, Susanna R. Stevens, Laine Thomas, Peter K. Smith, L Kristin Newby, Renato A. K. Kalil, John H. Alexander, and Renato D. Lopes. “Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate..” Brazilian Journal of Cardiovascular Surgery 31, no. 2 (April 2016): 106–14. https://doi.org/10.5935/1678-9741.20160019.
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    • Streiff, Michael B., Giancarlo Agnelli, Jean M. Connors, Mark Crowther, Sabine Eichinger, Renato D. Lopes, Robert D. McBane, Stephan Moll, and Jack Ansell. “Erratum to: Guidance for the treatment of deep vein thrombosis and pulmonary embolism..” Journal of Thrombosis and Thrombolysis 41, no. 3 (April 2016). https://doi.org/10.1007/s11239-016-1345-4.
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    • Zimerman, André, Renato D. Lopes, Amanda L. Stebbins, Patrícia O. Guimarães, Ghazala Haque, Chiara Melloni, Kathleen Trollinger, et al. “Pooled analysis of adverse event collection from 4 acute coronary syndrome trials..” American Heart Journal 174 (April 2016): 60–67. https://doi.org/10.1016/j.ahj.2016.01.003.
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    • Lopes, Renato D., Sergio Leonardi, Benjamin Neely, Megan L. Neely, E Magnus Ohman, Diego Ardissino, Christian W. Hamm, et al. “Spontaneous MI After Non-ST-Segment Elevation Acute Coronary Syndrome Managed Without Revascularization: The TRILOGY ACS Trial..” Journal of the American College of Cardiology 67, no. 11 (March 2016): 1289–97. https://doi.org/10.1016/j.jacc.2016.01.034.
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    • Rajpurohit, Naveen, Rajiv Gulati, Ryan J. Lennon, Mandeep Singh, Charanjit S. Rihal, Paula J. Santrach, Leslie J. Donato, et al. “Relation of Activated Clotting Times During Percutaneous Coronary Intervention to Outcomes..” The American Journal of Cardiology 117, no. 5 (March 2016): 703–8. https://doi.org/10.1016/j.amjcard.2015.12.003.
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    • Vavalle, John P., Sean van Diepen, Robert M. Clare, Judith S. Hochman, W Douglas Weaver, Rajendra H. Mehta, Karen S. Pieper, et al. “Renal failure in patients with ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention: Predictors, clinical and angiographic features, and outcomes..” American Heart Journal 173 (March 2016): 57–66. https://doi.org/10.1016/j.ahj.2015.12.001.
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    • Pesaro, Antonio Eduardo P., Christopher B. Granger, and Renato D. Lopes. “Reduction of ischemic events in Improved Reduction of Outcomes: Vytorin Efficacy International Trial: Intensive cholesterol lowering or ezetimibe antithrombotic effects?.” American Heart Journal 172 (February 2016): 42–44. https://doi.org/10.1016/j.ahj.2015.11.001.
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    • Sebben, Juliana C., Daniel R. Pinto Ribeiro, Renato D. Lopes, Robert de Winter, Ralf Harskamp, Eduardo Cambruzzi, Marcia Moura Schmidt, Eduarda Schutz Martinelli, Carlos A. Gottschall, and Alexandre S. Quadros. “The role of diabetes mellitus in the composition of coronary thrombi in patients presenting with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention..” American Heart Journal 172 (February 2016): 26–33. https://doi.org/10.1016/j.ahj.2015.10.003.
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    • Durheim, Michael T., Derek D. Cyr, Renato D. Lopes, Laine E. Thomas, Wayne M. Tsuang, Bernard J. Gersh, Claes Held, et al. “Chronic obstructive pulmonary disease in patients with atrial fibrillation: Insights from the ARISTOTLE trial..” International Journal of Cardiology 202 (January 2016): 589–94. https://doi.org/10.1016/j.ijcard.2015.09.062.
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    • Harskamp, Ralf E., John H. Alexander, T Bruce Ferguson, Rebecca Hager, Michael J. Mack, Brian Englum, Daniel Wojdyla, et al. “Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial..” Circulation 133, no. 2 (January 2016): 131–38. https://doi.org/10.1161/CIRCULATIONAHA.115.015549.
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    • Lincoff, A Michael, Roxana Mehran, Thomas J. Povsic, Steven L. Zelenkofske, Zhen Huang, Paul W. Armstrong, P Gabriel Steg, et al. “Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial..” Lancet (London, England) 387, no. 10016 (January 2016): 349–56. https://doi.org/10.1016/s0140-6736(15)00515-2.
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    • Pesaro, Antonio Eduardo P., Marcelo Katz, Jason N. Katz, Carmen Sílvia Valente Barbas, Marcia R. Makdisse, Alessandra G. Correa, Marcelo Franken, Carolina Pereira, Carlos V. Serrano, and Renato D. Lopes. “Mechanical Ventilation and Clinical Outcomes in Patients with Acute Myocardial Infarction: A Retrospective Observational Study..” Plos One 11, no. 3 (January 2016). https://doi.org/10.1371/journal.pone.0151302.
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    • Streiff, Michael B., Giancarlo Agnelli, Jean M. Connors, Mark Crowther, Sabine Eichinger, Renato Lopes, Robert D. McBane, Stephan Moll, and Jack Ansell. “Guidance for the treatment of deep vein thrombosis and pulmonary embolism..” Journal of Thrombosis and Thrombolysis 41, no. 1 (January 2016): 32–67. https://doi.org/10.1007/s11239-015-1317-0.
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    • Rao, Meena P., Sigrun Halvorsen, Daniel Wojdyla, Laine Thomas, John H. Alexander, Elaine M. Hylek, Michael Hanna, et al. “Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial..” Journal of the American Heart Association 4, no. 12 (December 2015). https://doi.org/10.1161/JAHA.115.002015.
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    • Vinereanu, Dragos, Susanna R. Stevens, John H. Alexander, Sana M. Al-Khatib, Alvaro Avezum, Marıa Cecilia Bahit, Christopher B. Granger, et al. “Clinical outcomes in patients with atrial fibrillation according to sex during anticoagulation with apixaban or warfarin: a secondary analysis of a randomized controlled trial..” European Heart Journal 36, no. 46 (December 2015): 3268–75. https://doi.org/10.1093/eurheartj/ehv447.
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    • Khan, Razi, Renato D. Lopes, Megan L. Neely, Susanna R. Stevens, Robert A. Harrington, Rafael Diaz, Frank Cools, et al. “Characterising and predicting bleeding in high-risk patients with an acute coronary syndrome..” Heart (British Cardiac Society) 101, no. 18 (September 2015): 1475–84. https://doi.org/10.1136/heartjnl-2014-307346.
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    • Avezum, Alvaro, Renato D. Lopes, Phillip J. Schulte, Fernando Lanas, Bernard J. Gersh, Michael Hanna, Prem Pais, et al. “Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial.” Circulation 132, no. 8 (August 25, 2015): 624–32. https://doi.org/10.1161/CIRCULATIONAHA.114.014807.
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    • Harskamp, Ralf E., Thomas A. Vassiliades, Rajendra H. Mehta, Robbert J. de Winter, Renato D. Lopes, Ying Xian, Eric D. Peterson, John D. Puskas, and Michael E. Halkos. “Comparative Effectiveness of Hybrid Coronary Revascularization vs Coronary Artery Bypass Grafting..” Journal of the American College of Surgeons 221, no. 2 (August 2015): 326-34.e1. https://doi.org/10.1016/j.jamcollsurg.2015.03.012.
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    • Hess, Connie N., Stefan James, Renato D. Lopes, Daniel M. Wojdyla, Megan L. Neely, Danny Liaw, Emil Hagstrom, et al. “Apixaban Plus Mono Versus Dual Antiplatelet Therapy in Acute Coronary Syndromes: Insights From the APPRAISE-2 Trial..” Journal of the American College of Cardiology 66, no. 7 (August 2015): 777–87. https://doi.org/10.1016/j.jacc.2015.06.027.
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    • Healey, Jeff S., Renato D. Lopes, and Stuart J. Connolly. “The detection and treatment of subclinical atrial fibrillation: evaluating the IMPACT of a comprehensive strategy based on remote arrhythmia monitoring..” European Heart Journal 36, no. 26 (July 2015): 1640–42. https://doi.org/10.1093/eurheartj/ehv159.
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    • Hess, Connie N., Renato D. Lopes, C Michael Gibson, Rebecca Hager, Daniel M. Wojdyla, Brian R. Englum, Michael J. Mack, Nicholas T. Kouchoukos, Eric D. Peterson, and John H. Alexander. “Response to Letters Regarding Article, "Saphenous Vein Graft Failure After Coronary Artery Bypass Surgery: Insights From PREVENT IV"..” Circulation 132, no. 4 (July 2015). https://doi.org/10.1161/CIRCULATIONAHA.115.015362.
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    • Williams, Judson B., Ralf E. Harskamp, Saideep Bose, Jeffrey H. Lawson, John H. Alexander, Peter K. Smith, and Renato D. Lopes. “The Preservation and Handling of Vein Grafts in Current Surgical Practice: Findings of a Survey Among Cardiovascular Surgeons of Top-Ranked US Hospitals..” Jama Surgery 150, no. 7 (July 2015): 681–83. https://doi.org/10.1001/jamasurg.2015.0404.
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    • Mahaffey, Kenneth W., Rebecca Hager, Daniel Wojdyla, Harvey D. White, Paul W. Armstrong, John H. Alexander, Pierluigi Tricoci, et al. “Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes..” Journal of the American Heart Association 4, no. 6 (June 18, 2015). https://doi.org/10.1161/JAHA.114.001512.
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    • Albuquerque, Denilson Campos de, João David de Souza Neto, Fernando Bacal, Luiz Eduardo Paim Rohde, Sabrina Bernardez-Pereira, Otavio Berwanger, Dirceu Rodrigues Almeida, and Dirceu Rodrigues Investigadores Estudo BREATHE. “I Brazilian Registry of Heart Failure - Clinical Aspects, Care Quality and Hospitalization Outcomes..” Arquivos Brasileiros De Cardiologia 104, no. 6 (June 2015): 433–42. https://doi.org/10.5935/abc.20150031.
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    • Armaganijan, Luciana V., Rodolfo Staico, Dalmo A. R. Moreira, Renato D. Lopes, Paulo T. J. Medeiros, Ricardo Habib, Jônatas Melo Neto, et al. “6-Month Outcomes in Patients With Implantable Cardioverter-Defibrillators Undergoing Renal Sympathetic Denervation for the Treatment of Refractory Ventricular Arrhythmias..” Jacc. Cardiovascular Interventions 8, no. 7 (June 2015): 984–90. https://doi.org/10.1016/j.jcin.2015.03.012.
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    • Armstrong, Paul W., Yinggan Zheng, Cynthia M. Westerhout, Fernado Rosell-Ortiz, Peter Sinnaeve, Yves Lambert, Renato D. Lopes, et al. “Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the STrategic Reperfusion Early After Myocardial infarction trial..” American Heart Journal 169, no. 6 (June 2015): 890-898.e1. https://doi.org/10.1016/j.ahj.2015.03.011.
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    • Lopes, Renato D., S Michael Gharacholou, DaJuanicia N. Holmes, Laine Thomas, Tracy Y. Wang, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI..” The American Journal of Medicine 128, no. 6 (June 2015): 582–90. https://doi.org/10.1016/j.amjmed.2014.12.032.
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    • Ciobanu, Andrea O., Sean Bennett, Renato D. Lopes, and Dragos Vinereanu. “Isolated Double Orifice Mitral Valve - a Rare Finding in an Elderly Man..” Arquivos Brasileiros De Cardiologia 104, no. 5 (May 2015): e53–54. https://doi.org/10.5935/abc.20150043.
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    • Held, Claes, Elaine M. Hylek, John H. Alexander, Michael Hanna, Renato D. Lopes, Daniel M. Wojdyla, Laine Thomas, et al. “Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial..” European Heart Journal 36, no. 20 (May 2015): 1264–72. https://doi.org/10.1093/eurheartj/ehu463.
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    • Cornel, Jan H., Renato D. Lopes, Stefan James, Susanna R. Stevens, Megan L. Neely, Danny Liaw, Julie Miller, et al. “Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial..” American Heart Journal 169, no. 4 (April 2015): 531–38. https://doi.org/10.1016/j.ahj.2014.12.022.
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    • Ezekowitz, Justin A., Basil S. Lewis, Renato D. Lopes, Daniel M. Wojdyla, John J. V. McMurray, Michael Hanna, Dan Atar, et al. “Clinical outcomes of patients with diabetes and atrial fibrillation treated with apixaban: results from the ARISTOTLE trial..” European Heart Journal. Cardiovascular Pharmacotherapy 1, no. 2 (April 2015): 86–94. https://doi.org/10.1093/ehjcvp/pvu024.
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    • Harskamp, Ralf E., Michael E. Halkos, Ying Xian, Molly A. Szerlip, Robert S. Poston, Stephanie L. Mick, Renato D. Lopes, Jan G. Tijssen, Robbert J. de Winter, and Eric D. Peterson. “A nationwide survey on perception, experience, and expectations of hybrid coronary revascularization among top-ranked US hospitals..” American Heart Journal 169, no. 4 (April 2015): 557-63.e6. https://doi.org/10.1016/j.ahj.2015.01.003.
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    • Katz, Marcelo, Robert M. Califf, Jie-Lena Sun, John J. V. McMurray, Laine Thomas, and Renato D. Lopes. “Venous thromboembolism and cardiovascular risk: results from the NAVIGATOR trial..” The American Journal of Medicine 128, no. 3 (March 2015): 297–302. https://doi.org/10.1016/j.amjmed.2014.08.022.
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    • Krishnamoorthy, Arun, Matthew W. Sherwood, Renato D. Lopes, and Richard C. Becker. “The periprocedural management of novel oral anticoagulants in patients with nonvalvular atrial fibrillation: rationale and a summary of the available evidence from phase 3 clinical trials..” American Heart Journal 169, no. 3 (March 2015): 315–22. https://doi.org/10.1016/j.ahj.2014.12.008.
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    • Hijazi, Ziad, Agneta Siegbahn, Ulrika Andersson, Bertil Lindahl, Christopher B. Granger, John H. Alexander, Dan Atar, et al. “Comparison of cardiac troponins I and T measured with high-sensitivity methods for evaluation of prognosis in atrial fibrillation: an ARISTOTLE substudy..” Clinical Chemistry 61, no. 2 (February 2015): 368–78. https://doi.org/10.1373/clinchem.2014.226936.
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    • Putera, Martin, Robin Roark, Renato D. Lopes, Krishna Udayakumar, Eric D. Peterson, Robert M. Califf, and Bimal R. Shah. “Translation of acute coronary syndrome therapies: from evidence to routine clinical practice..” American Heart Journal 169, no. 2 (February 2015): 266–73. https://doi.org/10.1016/j.ahj.2014.09.015.
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    • Cornel, J. H., R. D. Lopes, S. James, S. R. Stevens, M. L. Neely, D. Liaw, J. Miller, et al. “Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial.” American Heart Journal 169, no. 4 (January 1, 2015): 531–38. https://doi.org/10.1016/j.ahj.2014.12.022.
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    • Granger, C. B., R. D. Lopes, M. Hanna, J. Ansell, E. M. Hylek, J. H. Alexander, L. Thomas, et al. “Erratum: Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the ARISTOTLE trial (American Heart Journal (2014) 169:1 (2530) DOI: 10.1016/j.ahj.2014.09.006).” American Heart Journal 169, no. 4 (January 1, 2015). https://doi.org/10.1016/j.ahj.2015.02.005.
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    • Granger, Christopher B., Renato D. Lopes, Michael Hanna, Jack Ansell, Elaine M. Hylek, John H. Alexander, Laine Thomas, et al. “Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial..” American Heart Journal 169, no. 1 (January 2015): 25–30. https://doi.org/10.1016/j.ahj.2014.09.006.
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    • Guimarães, Patrícia O., Scott Kaatz, and Renato D. Lopes. “Practical and clinical considerations in assessing patients with atrial fibrillation for switching to non-vitamin K antagonist oral anticoagulants in primary care..” International Journal of General Medicine 8 (January 2015): 283–91. https://doi.org/10.2147/IJGM.S62760.
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    • Harskamp, R. E., M. E. Halkos, Y. Xian, M. A. Szerlip, R. S. Poston, S. L. Mick, R. D. Lopes, J. G. Tijssen, R. J. De Winter, and E. D. Peterson. “A nationwide survey on perception, experience, and expectations of hybrid coronary revascularization among top-ranked US hospitals.” American Heart Journal 169, no. 4 (January 1, 2015): 557-563.e6. https://doi.org/10.1016/j.ahj.2015.01.003.
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    • Katz, M., R. M. Califf, J. L. Sun, J. J. V. McMurray, L. Thomas, and R. D. Lopes. “Venous thromboembolism and cardiovascular risk: Results from the NAVIGATOR trial.” American Journal of Medicine 128, no. 3 (January 1, 2015): 297–302. https://doi.org/10.1016/j.amjmed.2014.08.022.
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    • Khan, R., R. D. Lopes, M. L. Neely, S. R. Stevens, R. A. Harrington, R. Diaz, F. Cools, et al. “Characterising and predicting bleeding in high-risk patients with an acute coronary syndrome.” Heart, 2015. https://doi.org/10.1136/heartjnl-2014-307346.
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    • Koshizaka, Masaya, Renato D. Lopes, Eric M. Reyes, C Michael Gibson, Phillip J. Schulte, Gail E. Hafley, Adrian F. Hernandez, et al. “Long-term clinical and angiographic outcomes in patients with diabetes undergoing coronary artery bypass graft surgery: results from the Project of Ex-vivo Vein Graft Engineering via Transfection IV trial..” American Heart Journal 169, no. 1 (January 2015): 175–84. https://doi.org/10.1016/j.ahj.2014.10.013.
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    • Nutescu, Edith A., Ann K. Wittkowsky, Daniel M. Witt, Scott Kaatz, Jack Ansell, Allison Burnett, David Garcia, et al. “Integrating electronic health records in the delivery of optimized anticoagulation therapy..” The Annals of Pharmacotherapy 49, no. 1 (January 2015): 125–26. https://doi.org/10.1177/1060028014548570.
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    • Welsh, R. C., F. Van De Werf, C. M. Westerhout, P. Goldstein, A. H. Gershlick, R. G. Wilcox, T. Danays, et al. “Outcomes of a pharmacoinvasive strategy for successful versus failed fibrinolysis and primary percutaneous intervention in acute myocardial infarction (from the strategic reperfusion early after myocardial infarction [STREAM] study).” American Journal of Cardiology 114, no. 6 (January 1, 2015): 811–19. https://doi.org/10.1016/j.amjcard.2014.06.011.
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    • Garcia, David, John H. Alexander, Lars Wallentin, Daniel M. Wojdyla, Laine Thomas, Michael Hanna, Sana M. Al-Khatib, et al. “Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures..” Blood 124, no. 25 (December 2014): 3692–98. https://doi.org/10.1182/blood-2014-08-595496.
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    • Gracieux, Junève, Gillian D. Sanders, Sean D. Pokorney, Renato D. Lopes, Kevin Thomas, and Sana M. Al-Khatib. “Incidence and predictors of appropriate therapies delivered by the implantable cardioverter defibrillator in patients with ischemic cardiomyopathy: a systematic review..” International Journal of Cardiology 177, no. 3 (December 2014): 990–94. https://doi.org/10.1016/j.ijcard.2014.09.170.
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    • Harskamp, Ralf E., Murad Abdelsalam, Renato D. Lopes, Gouthami Boga, Sameer Hirji, Mrinalini Krishnan, Lukasz Kiljanek, et al. “Cardiac troponin release following hybrid coronary revascularization versus off-pump coronary artery bypass surgery..” Interactive Cardiovascular and Thoracic Surgery 19, no. 6 (December 2014): 1008–12. https://doi.org/10.1093/icvts/ivu297.
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    • Hohnloser, Stefan H., and Renato D. Lopes. “Atrial fibrillation, valvular heart disease, and use of target-specific oral anticoagulants for stroke prevention..” European Heart Journal 35, no. 47 (December 2014): 3323–25. https://doi.org/10.1093/eurheartj/ehu386.
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    • Harskamp, R. E., J. B. Williams, M. E. Halkos, R. D. Lopes, J. G. P. Tijssen, T. B. Ferguson, and R. J. De Winter. “Meta-analysis of minimally invasive coronary artery bypass versus drug-eluting stents for isolated left anterior descending coronary artery disease.” Journal of Thoracic and Cardiovascular Surgery 148, no. 5 (November 1, 2014): 1837–42. https://doi.org/10.1016/j.jtcvs.2014.03.028.
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    • Harskamp, Ralf E., Judson B. Williams, Michael E. Halkos, Renato D. Lopes, Jan G. P. Tijssen, T Bruce Ferguson, and Robbert J. de Winter. “Meta-analysis of minimally invasive coronary artery bypass versus drug-eluting stents for isolated left anterior descending coronary artery disease..” The Journal of Thoracic and Cardiovascular Surgery 148, no. 5 (November 2014): 1837–42. https://doi.org/10.1016/j.jtcvs.2014.03.028.
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    • Harskamp, Ralf E., Phillip J. Schulte, John H. Alexander, and Renato D. Lopes. “Reply: To PMID 24360877..” The Annals of Thoracic Surgery 98, no. 5 (November 2014). https://doi.org/10.1016/j.athoracsur.2014.08.076.
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    • Harskamp, Ralf E., Phillip J. Schulte, John H. Alexander, and Renato D. Lopes. “About the Impact of Extracardiac Vascular Disease on Vein Graft Failure Reply.” Annals of Thoracic Surgery 98, no. 5 (November 2014): 1890–1890. https://doi.org/10.1016/j.athoracsur.2014.08.076.
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    • Wallentin, Lars, Ziad Hijazi, Ulrika Andersson, John H. Alexander, Raffaele De Caterina, Michael Hanna, John D. Horowitz, et al. “Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial..” Circulation 130, no. 21 (November 2014): 1847–58. https://doi.org/10.1161/circulationaha.114.011204.
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    • Ansell, Jack, Mark Crowther, Allison Burnett, David Garcia, Scott Kaatz, Renato D. Lopes, Edith Nutescu, et al. “Comment on: editorial by Husted et al. "Non-vitamin K antagonist oral anticoagulants (NOACs): no longer new or novel". (Thromb Haemost 2014; 111: 781-782)..” Thrombosis and Haemostasis 112, no. 4 (October 2014). https://doi.org/10.1160/th14-04-0325.
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    • Bagai, Akshay, Phillip J. Schulte, Christopher B. Granger, Kenneth W. Mahaffey, Robert H. Christenson, Gregory Bell, Renato D. Lopes, et al. “Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention..” American Heart Journal 168, no. 4 (October 2014): 503-511.e2. https://doi.org/10.1016/j.ahj.2014.06.008.
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    • Barros e Silva, Pedro G. M. de, Robert M. Califf, Jie-Lena Sun, John J. V. McMurray, Rury Holman, Steven Haffner, Laine Thomas, and Renato D. Lopes. “Chronic obstructive pulmonary disease and cardiovascular risk: insights from the NAVIGATOR trial..” International Journal of Cardiology 176, no. 3 (October 2014): 1126–28. https://doi.org/10.1016/j.ijcard.2014.07.297.
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    • Flaker, Greg, Renato D. Lopes, Elaine Hylek, Daniel M. Wojdyla, Laine Thomas, Sana M. Al-Khatib, Renee M. Sullivan, et al. “Amiodarone, anticoagulation, and clinical events in patients with atrial fibrillation: insights from the ARISTOTLE trial..” Journal of the American College of Cardiology 64, no. 15 (October 2014): 1541–50. https://doi.org/10.1016/j.jacc.2014.07.967.
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    • Hess, Connie N., Renato D. Lopes, C Michael Gibson, Rebecca Hager, Daniel M. Wojdyla, Brian R. Englum, Michael J. Mack, et al. “Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV..” Circulation 130, no. 17 (October 2014): 1445–51. https://doi.org/10.1161/CIRCULATIONAHA.113.008193.
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    • Christersson, C., L. Wallentin, U. Andersson, J. H. Alexander, J. Ansell, R. De Caterina, B. J. Gersh, et al. “D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation--observations from the ARISTOTLE trial..” Journal of Thrombosis and Haemostasis : Jth 12, no. 9 (September 2014): 1401–12. https://doi.org/10.1111/jth.12638.
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    • Goto, Shinya, Jun Zhu, Lisheng Liu, Byung-Hee Oh, Daniel M. Wojdyla, Philip Aylward, M Cecilia Bahit, et al. “Efficacy and safety of apixaban compared with warfarin for stroke prevention in patients with atrial fibrillation from East Asia: a subanalysis of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial..” American Heart Journal 168, no. 3 (September 2014): 303–9. https://doi.org/10.1016/j.ahj.2014.06.005.
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    • Steinberg, Benjamin A., Samuel H. Broderick, Renato D. Lopes, Linda K. Shaw, Kevin L. Thomas, Tracy A. DeWald, James P. Daubert, Eric D. Peterson, Christopher B. Granger, and Jonathan P. Piccini. “Use of antiarrhythmic drug therapy and clinical outcomes in older patients with concomitant atrial fibrillation and coronary artery disease..” Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology 16, no. 9 (September 2014): 1284–90. https://doi.org/10.1093/europace/euu077.
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    • Steinberg, Benjamin A., Samuel H. Broderick, Renato D. Lopes, Linda K. Shaw, Kevin L. Thomas, Tracy A. DeWald, James P. Daubert, Eric D. Peterson, Christopher B. Granger, and Jonathan P. Piccini. “Use of antiarrhythmic drug therapy and clinical outcomes in older patients with concomitant atrial fibrillation and coronary artery disease.” Europace 16, no. 9 (September 2014): 1284–90. https://doi.org/10.1093/europace/euu077.
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    • Tallo, Fernando Sabia, Simone de Campos Vieira Abib, André Luciano Baitello, and Renato Delascio Lopes. “An evaluation of the professional, social and demographic profile and quality of life of physicians working at the Prehospital Emergency Medical System (SAMU) in Brazil..” Clinics 69, no. 9 (September 2014): 601–7. https://doi.org/10.6061/clinics/2014(09)05.
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    • Testoni, Daniela, Madoka Hayashi, Michael Cohen-Wolkowiez, Daniel K. Benjamin, Renato D. Lopes, Reese H. Clark, and P Brian Smith. “Late-onset bloodstream infections in hospitalized term infants..” The Pediatric Infectious Disease Journal 33, no. 9 (September 2014): 920–23. https://doi.org/10.1097/INF.0000000000000322.
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    • Welsh, Robert C., Frans Van de Werf, Cynthia M. Westerhout, Patrick Goldstein, Anthony H. Gershlick, Robert G. Wilcox, Thierry Danays, et al. “Outcomes of a pharmacoinvasive strategy for successful versus failed fibrinolysis and primary percutaneous intervention in acute myocardial infarction (from the STrategic Reperfusion Early After Myocardial Infarction [STREAM] study)..” The American Journal of Cardiology 114, no. 6 (September 2014): 811–19. https://doi.org/10.1016/j.amjcard.2014.06.011.
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    • Bernardez-Pereira, Sabrina, Renato D. Lopes, Maria Julia Machline Carrion, Eliana Vieira Santucci, Rafael Marques Soares, Matheus de Oliveira Abreu, Ligia Nasi Laranjeira, et al. “Prevalence, characteristics, and predictors of early termination of cardiovascular clinical trials due to low recruitment: insights from the ClinicalTrials.gov registry..” American Heart Journal 168, no. 2 (August 2014): 213-9.e1. https://doi.org/10.1016/j.ahj.2014.04.013.
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    • Diepen, Sean van, J Matthew Brennan, Gail E. Hafley, Eric M. Reyes, Keith B. Allen, T Bruce Ferguson, Eric D. Peterson, et al. “Endoscopic harvesting device type and outcomes in patients undergoing coronary artery bypass surgery..” Ann Surg 260, no. 2 (August 2014): 402–8. https://doi.org/10.1097/SLA.0000000000000377.
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    • Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, Colleen M. Brophy, Michael J. Mack, Eric D. Peterson, Judson B. Williams, et al. “Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from the PREVENT IV randomized clinical trial..” Jama Surgery 149, no. 8 (August 2014): 798–805. https://doi.org/10.1001/jamasurg.2014.87.
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    • Halvorsen, Sigrun, Dan Atar, Hongqiu Yang, Raffaele De Caterina, Cetin Erol, David Garcia, Christopher B. Granger, et al. “Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial..” European Heart Journal 35, no. 28 (July 2014): 1864–72. https://doi.org/10.1093/eurheartj/ehu046.
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    • Harskamp, Ralf E., John D. Puskas, Jan G. Tijssen, Patrick F. Walker, Henry A. Liberman, Renato D. Lopes, Thomas A. Vassiliades, Eric D. Peterson, and Michael E. Halkos. “Comparison of hybrid coronary revascularization versus coronary artery bypass grafting in patients≥65 years with multivessel coronary artery disease..” The American Journal of Cardiology 114, no. 2 (July 2014): 224–29. https://doi.org/10.1016/j.amjcard.2014.04.028.
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    • Castleberry, A. W., J. B. Williams, M. A. Daneshmand, E. Honeycutt, L. K. Shaw, Z. Samad, R. D. Lopes, et al. “Surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: A 20-year experience.” Circulation 129, no. 24 (June 17, 2014): 2547–56. https://doi.org/10.1161/CIRCULATIONAHA.113.005223.
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    • Al-Khatib, Sana M., Nancy M. Allen LaPointe, Ranee Chatterjee, Matthew J. Crowley, Matthew E. Dupre, David F. Kong, Renato D. Lopes, et al. “Rate- and rhythm-control therapies in patients with atrial fibrillation: a systematic review..” Annals of Internal Medicine 160, no. 11 (June 2014): 760–73. https://doi.org/10.7326/m13-1467.
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    • Castleberry, Anthony W., Judson B. Williams, Mani A. Daneshmand, Emily Honeycutt, Linda K. Shaw, Zainab Samad, Renato D. Lopes, et al. “Surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience..” Circulation 129, no. 24 (June 2014): 2547–56. https://doi.org/10.1161/CIRCULATIONAHA.113.005223.
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    • Hylek, Elaine M., Claes Held, John H. Alexander, Renato D. Lopes, Raffaele De Caterina, Daniel M. Wojdyla, Kurt Huber, et al. “Major bleeding in patients with atrial fibrillation receiving apixaban or warfarin: The ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation): Predictors, Characteristics, and Clinical Outcomes..” Journal of the American College of Cardiology 63, no. 20 (May 2014): 2141–47. https://doi.org/10.1016/j.jacc.2014.02.549.
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    • Staico, Rodolfo, Luciana Armaganijan, Dalmo Moreira, Paulo Medeiros, Jonatas Melo, Renato Lopes, José Ribamar Costa, and Alexandre Abizaid. “Renal sympathetic denervation and ventricular arrhythmias: a case of electrical storm with multiple renal arteries..” Eurointervention : Journal of Europcr in Collaboration With the Working Group on Interventional Cardiology of the European Society of Cardiology 10, no. 1 (May 2014). https://doi.org/10.4244/eijv10i1a25.
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    • Harskamp, Ralf E., Akshay Bagai, Michael E. Halkos, Sunil V. Rao, William B. Bachinsky, Manesh R. Patel, Robbert J. de Winter, Eric D. Peterson, John H. Alexander, and Renato D. Lopes. “Clinical outcomes after hybrid coronary revascularization versus coronary artery bypass surgery: a meta-analysis of 1,190 patients..” American Heart Journal 167, no. 4 (April 2014): 585–92. https://doi.org/10.1016/j.ahj.2014.01.006.
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    • Nelson, James A., John P. Vavalle, Christopher H. May, Aijing Zhang, L Kristin Newby, Linda K. Shaw, Sana M. Al-Khatib, John H. Alexander, Christopher B. Granger, and Renato D. Lopes. “Warfarin use and long-term outcomes in patients with acute myocardial infarction and atrial fibrillation..” Journal of Thrombosis and Thrombolysis 37, no. 3 (April 2014): 331–37. https://doi.org/10.1007/s11239-013-0946-4.
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    • Flaker, Greg, Renato D. Lopes, Sana M. Al-Khatib, Antonio G. Hermosillo, Stefan H. Hohnloser, Brian Tinga, Jun Zhu, et al. “Efficacy and safety of apixaban in patients after cardioversion for atrial fibrillation: insights from the ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation)..” Journal of the American College of Cardiology 63, no. 11 (March 2014): 1082–87. https://doi.org/10.1016/j.jacc.2013.09.062.
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    • Harskamp, R. E., J. H. Alexander, P. J. Schulte, W. S. Jones, J. B. Williams, M. J. Mack, E. D. Peterson, et al. “Impact of extracardiac vascular disease on vein graft failure and outcomes after coronary artery bypass surgery.” Annals of Thoracic Surgery 97, no. 3 (March 1, 2014): 824–30. https://doi.org/10.1016/j.athoracsur.2013.09.099.
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    • Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, W Schuyler Jones, Judson B. Williams, Michael J. Mack, Eric D. Peterson, et al. “Impact of extracardiac vascular disease on vein graft failure and outcomes after coronary artery bypass surgery..” The Annals of Thoracic Surgery 97, no. 3 (March 2014): 824–30. https://doi.org/10.1016/j.athoracsur.2013.09.099.
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    • Lopes, R. D., and L. K. Newby. “Response to the Letter to the Editor titled "atrial fibrillation in patients with acute coronary syndromes".” International Journal of Cardiology 171, no. 3 (February 15, 2014). https://doi.org/10.1016/j.ijcard.2013.12.006.
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    • Hijazi, Z., A. Siegbahn, U. Andersson, C. B. Granger, J. H. Alexander, D. Atar, B. J. Gersh, et al. “High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: Insights from the apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial.” Circulation 129, no. 6 (February 11, 2014): 625–34. https://doi.org/10.1161/CIRCULATIONAHA.113.006286.
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    • Diepen, Sean van, Harmony R. Reynolds, Amanda Stebbins, Renato D. Lopes, Vladimír Džavík, Witold Ruzyllo, Alexander Geppert, et al. “Incidence and outcomes associated with early heart failure pharmacotherapy in patients with ongoing cardiogenic shock..” Critical Care Medicine 42, no. 2 (February 2014): 281–88. https://doi.org/10.1097/ccm.0b013e31829f6242.
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    • Hijazi, Ziad, Agneta Siegbahn, Ulrika Andersson, Christopher B. Granger, John H. Alexander, Dan Atar, Bernard J. Gersh, et al. “High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial..” Circulation 129, no. 6 (February 2014): 625–34. https://doi.org/10.1161/circulationaha.113.006286.
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    • Lopes, Renato D., and L Kristin Newby. “Response to the Letter to the Editor titled "Atrial fibrillation in patients with acute coronary syndromes"..” International Journal of Cardiology 171, no. 3 (February 2014). https://doi.org/10.1016/j.ijcard.2013.12.006.
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    • Hijazi, Ziad, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, John H. Alexander, Dan Atar, Bernard J. Gersh, et al. “High-Sensitivity Troponin T and Risk Stratification in Patients With Atrial Fibrillation During Treatment With Apixaban or Warfarin.” Journal of the American College of Cardiology 63, no. 1 (January 7, 2014): 52–61. https://doi.org/10.1016/j.jacc.2013.07.093.
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    • Alexander, John H., Renato D. Lopes, Laine Thomas, Marco Alings, Dan Atar, Philip Aylward, Shinya Goto, et al. “Apixaban vs. warfarin with concomitant aspirin in patients with atrial fibrillation: insights from the ARISTOTLE trial..” European Heart Journal 35, no. 4 (January 2014): 224–32. https://doi.org/10.1093/eurheartj/eht445.
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    • Bagai, A., P. J. Schulte, C. B. Granger, K. W. Mahaffey, R. H. Christenson, G. Bell, R. D. Lopes, et al. “Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention.” American Heart Journal 168, no. 4 (January 1, 2014): 503-511.e2. https://doi.org/10.1016/j.ahj.2014.06.008.
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    • Bernardez-Pereira, S., R. D. Lopes, M. J. M. Carrion, E. V. Santucci, R. M. Soares, M. De Oliveira Abreu, L. N. Laranjeira, et al. “Prevalence, characteristics, and predictors of early termination of cardiovascular clinical trials due to low recruitment: Insights from the ClinicalTrials.gov registry.” American Heart Journal 168, no. 2 (January 1, 2014). https://doi.org/10.1016/j.ahj.2014.04.013.
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    • Christersson, C., L. Wallentin, U. Andersson, J. H. Alexander, J. Ansell, R. De Caterina, B. J. Gersh, et al. “D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation - observations from the ARISTOTLE trial.” Journal of Thrombosis and Haemostasis 12, no. 9 (January 1, 2014): 1401–12. https://doi.org/10.1111/jth.12638.
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    • Diepen, S. V., H. R. Reynolds, A. Stebbins, R. D. Lopes, V. Džavík, W. Ruzyllo, A. Geppert, et al. “Incidence and outcomes associated with early heart failure pharmacotherapy in patients with ongoing cardiogenic shock.” Critical Care Medicine 42, no. 2 (2014): 281–88. https://doi.org/10.1097/CCM.0b013e31829f6242.
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    • Diepen, S. V., J. M. Brennan, G. E. Hafley, E. M. Reyes, K. B. Allen, T. B. Ferguson, E. D. Peterson, et al. “Endoscopic harvesting device type and outcomes in patients undergoing coronary artery bypass surgery.” Annals of Surgery 260, no. 2 (2014): 402–8. https://doi.org/10.1097/SLA.0000000000000377.
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    • Goto, S., J. Zhu, L. Liu, B. H. Oh, D. M. Wojdyla, P. Aylward, M. C. Bahit, et al. “Efficacy and safety of apixaban compared with warfarin for stroke prevention in patients with atrial fibrillation from East Asia: A subanalysis of the apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial.” American Heart Journal 168, no. 3 (January 1, 2014): 303–9. https://doi.org/10.1016/j.ahj.2014.06.005.
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    • Granger, C. B., R. D. Lopes, M. Hanna, J. Ansell, E. M. Hylek, J. H. Alexander, L. Thomas, et al. “Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.” American Heart Journal 169, no. 1 (January 1, 2014): 25–30. https://doi.org/10.1016/j.ahj.2014.09.006.
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    • Hess, C. N., R. D. Lopes, C. M. Gibson, R. Hager, D. M. Wojdyla, B. R. Englum, M. J. Mack, et al. “Saphenous vein graft failure after coronary artery bypass surgery insights from PREVENT IV.” Circulation 130, no. 17 (January 1, 2014): 1445–51. https://doi.org/10.1161/CIRCULATIONAHA.113.008193.
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    • Koshizaka, M., R. D. Lopes, E. M. Reyes, C. M. Gibson, P. J. Schulte, G. E. Hafley, A. F. Hernandez, et al. “Long-term clinical and angiographic outcomes in patients with diabetes undergoing coronary artery bypass graft surgery: Results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV Trial.” American Heart Journal 169, no. 1 (January 1, 2014): 175–84. https://doi.org/10.1016/j.ahj.2014.10.013.
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    • Testoni, D., M. Hayashi, M. Cohen-Wolkowiez, D. K. Benjamin, R. D. Lopes, R. H. Clark, D. K. Benjamn, and P. B. Smith. “Late-onset bloodstream infections in hospitalized term infants.” Pediatric Infectious Disease Journal 33, no. 9 (January 1, 2014): 920–23. https://doi.org/10.1097/INF.0000000000000322.
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    • Wallentin, Lars, Renato D. Lopes, Michael Hanna, Laine Thomas, Anne Hellkamp, Sunil Nepal, Elaine M. Hylek, et al. “Response to letter regarding article, "Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation"..” Circulation 129, no. 2 (January 2014): e21–22. https://doi.org/10.1161/circulationaha.113.005709.
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    • Welsh, R. C., F. Van de Werf, C. M. Westerhout, P. Goldstein, A. H. Gershlick, R. G. Wilcox, T. Danays, et al. “Outcomes of a pharmacoinvasive strategy for successful versus failed fibrinolysis and primary percutaneous intervention in acute myocardial infarction (from the STrategic Reperfusion Early After Myocardial Infarction [STREAM] study)..” The American Journal of Cardiology 114, no. 6 (January 1, 2014): 811–19.
    • Williams, J. B., E. D. Peterson, D. Wojdyla, R. Harskamp, K. W. Southerland, T. B. Ferguson, P. K. Smith, C. A. Milano, and R. D. Lopes. “Central venous pressure after coronary artery bypass surgery: Does it predict postoperative mortality or renal failure?.” Journal of Critical Care 29, no. 6 (January 1, 2014): 1006–10. https://doi.org/10.1016/j.jcrc.2014.05.027.
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    • Bahit, M. C., R. D. Lopes, D. M. Wojdyla, S. H. Hohnloser, J. H. Alexander, B. S. Lewis, P. E. Aylward, et al. “Apixaban in patients with atrial fibrillation and prior coronary artery disease: Insights from the ARISTOTLE trial.” International Journal of Cardiology 170, no. 2 (December 10, 2013): 215–20. https://doi.org/10.1016/j.ijcard.2013.10.062.
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    • Bahit, Maria Cecilia, Renato D. Lopes, Daniel M. Wojdyla, Stefan H. Hohnloser, John H. Alexander, Basil S. Lewis, Philip E. Aylward, et al. “Apixaban in patients with atrial fibrillation and prior coronary artery disease: insights from the ARISTOTLE trial..” International Journal of Cardiology 170, no. 2 (December 2013): 215–20. https://doi.org/10.1016/j.ijcard.2013.10.062.
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    • Harskamp, Ralf E., Zhe Zheng, John H. Alexander, Judson B. Williams, Ying Xian, Michael E. Halkos, J Matthew Brennan, Robbert J. de Winter, Peter K. Smith, and Renato D. Lopes. “Status quo of hybrid coronary revascularization for multi-vessel coronary artery disease..” The Annals of Thoracic Surgery 96, no. 6 (December 2013): 2268–77. https://doi.org/10.1016/j.athoracsur.2013.07.093.
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    • Lauzier, François, Donald M. Arnold, Christian Rabbat, Diane Heels-Ansdell, Ryan Zarychanski, Peter Dodek, Betty Jean Ashley, et al. “Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis..” Intensive Care Medicine 39, no. 12 (December 2013): 2135–43. https://doi.org/10.1007/s00134-013-3044-3.
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    • Harskamp, RE, Zheng, Z, Alexander, JH, Williams, JB, Xian, Y, Halkos, ME, Brennan, JM, De Winter, RJ, Smith, PK, and Lopes, RD. "Status quo of hybrid coronary revascularization for multi-vessel coronary artery disease." Annals of Thoracic Surgery 96, no. 6 (December 1, 2013): 2268-2277. (Review)  Full Text
    • Papa, EDE, Helber, I, Ehrlichmann, MR, Alves, CMR, Makdisse, M, Matos, LN, Borges, JL, Lopes, RD, Stefanini, E, and Carvalho, AC. "Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography." Clinics 68, no. 12 (December 2013): 1481-1487.  Full Text
    • Azevedo, Rudyney E. U., Renato D. Lopes, Maria Eugênia F. Canziani, Iran Gonçalves, Paulo Cesar G. D. Campos, Marcelo L. C. Vieira, Edson Stefanini, and Antonio C. Carvalho. “Mortality after myocardial infarction: the role of renal function and systolic and diastolic functions of the left ventricle..” Journal of Nephrology 26, no. 6 (November 18, 2013): 1089–96. https://doi.org/10.5301/jn.5000294.
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    • Armaganijan, Luciana, Dalmo A. Moreira, Roberta R. Nolasco de Araújo, Marcelo A. Puzzi, Fernando P. Munhoz, Murilo J. Carvalho, Lilian N. Gallo, João Italo D. França, and Renato D. Lopes. “The usefulness of T-wave peak to T-wave end interval in identifying malignant arrhythmias in patients with Chagas disease..” Hellenic Journal of Cardiology : Hjc = Hellenike Kardiologike Epitheorese 54, no. 6 (November 2013): 429–34.
    • Bagai, A., P. W. Armstrong, A. Stebbins, K. W. Mahaffey, J. S. Hochman, W. D. Weaver, M. R. Patel, C. B. Granger, and R. D. Lopes. “Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study.” American Heart Journal 166, no. 5 (November 1, 2013): 913–19. https://doi.org/10.1016/j.ahj.2013.08.006.
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    • Bagai, Akshay, Paul W. Armstrong, Amanda Stebbins, Kenneth W. Mahaffey, Judith S. Hochman, W Douglas Weaver, Manesh R. Patel, Christopher B. Granger, and Renato D. Lopes. “Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study..” American Heart Journal 166, no. 5 (November 2013): 913–19. https://doi.org/10.1016/j.ahj.2013.08.006.
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    • Fosbol, E. L., T. Y. Wang, S. Li, J. Piccini, R. D. Lopes, R. M. Mills, W. Klaskala, L. Thomas, M. T. Roe, and E. D. Peterson. “Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy.” American Heart Journal 166, no. 5 (November 1, 2013): 864–70. https://doi.org/10.1016/j.ahj.2013.08.005.
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    • Fosbol, Emil L., Tracy Y. Wang, Shuang Li, Jonathan Piccini, Renato D. Lopes, Roger M. Mills, Winslow Klaskala, Laine Thomas, Matthew T. Roe, and Eric D. Peterson. “Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy..” American Heart Journal 166, no. 5 (November 2013): 864–70. https://doi.org/10.1016/j.ahj.2013.08.005.
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    • Parashar, Susmita, Danesh Kella, Kimberly J. Reid, John A. Spertus, Fengming Tang, Jonathan Langberg, Viola Vaccarino, Michael C. Kontos, Renato D. Lopes, and Michael S. Lloyd. “New-onset atrial fibrillation after acute myocardial infarction and its relation to admission biomarkers (from the TRIUMPH registry)..” The American Journal of Cardiology 112, no. 9 (November 2013): 1390–95. https://doi.org/10.1016/j.amjcard.2013.07.006.
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    • Williams, Judson B., Renato D. Lopes, Gail E. Hafley, T Bruce Ferguson, Michael J. Mack, C Michael Gibson, Robert A. Harrington, et al. “Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting..” Journal of Thrombosis and Thrombolysis 36, no. 4 (November 2013): 384–93. https://doi.org/10.1007/s11239-013-0904-1.
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    • Williams, JB, Lopes, RD, Hafley, GE, Bruce Ferguson, T, Mack, MJ, Michael Gibson, C, Harrington, RA, Peterson, ED, Smith, PK, Mehta, RH, and Alexander, JH. "Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting." Journal of Thrombosis and Thrombolysis 36, no. 4 (November 1, 2013): 384-393.  Full Text
    • Ritt, L. E., A. C. Carvalho, G. S. Feitosa, J. A. Pinho-Filho, M. V. S. Andrade, G. S. Feitosa-Filho, L. K. Newby, and R. D. Lopes. “Cardiopulmonary exercise and 6-min walk tests as predictors of quality of life and long-term mortality among patients with heart failure due to Chagas disease.” International Journal of Cardiology 168, no. 4 (October 9, 2013): 4584–85. https://doi.org/10.1016/j.ijcard.2013.06.064.
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    • Schmidt, M. M., R. D. Lopes, L. K. Newby, M. R. Moura, L. Stochero, C. M. Gottschall, and A. S. Quadros. “Anger control and cardiovascular outcomes.” International Journal of Cardiology 168, no. 4 (October 9, 2013): 4338–39. https://doi.org/10.1016/j.ijcard.2013.05.083.
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    • Diepen, Sean van, L Kristin Newby, Renato D. Lopes, Amanda Stebbins, Vic Hasselblad, Stefan James, Matthew T. Roe, et al. “Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: an APEX AMI substudy..” International Journal of Cardiology 168, no. 3 (October 2013): 2127–33. https://doi.org/10.1016/j.ijcard.2013.01.004.
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    • Giraldez, Roberto Rocha, Renato D. Lopes, and L Kristin Newby. “Responding to the letter to the editor by Saver..” American Heart Journal 166, no. 4 (October 2013). https://doi.org/10.1016/j.ahj.2013.08.022.
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    • Lopes, Renato D., Jennifer A. White, Dan Atar, Matyas Keltai, Neal S. Kleiman, Harvey D. White, Petr Widimsky, et al. “Incidence, treatment, and outcomes of atrial fibrillation complicating non-ST-segment elevation acute coronary syndromes..” International Journal of Cardiology 168, no. 3 (October 2013): 2510–17. https://doi.org/10.1016/j.ijcard.2013.03.037.
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    • Ritt, Luiz Eduardo, Antonio Carlos Carvalho, Gilson Soares Feitosa, Joel A. Pinho-Filho, Marcus Vinicius Santos Andrade, Gilson Soares Feitosa-Filho, L Kristin Newby, and Renato D. Lopes. “Cardiopulmonary exercise and 6-min walk tests as predictors of quality of life and long-term mortality among patients with heart failure due to Chagas disease..” International Journal of Cardiology 168, no. 4 (October 2013): 4584–85. https://doi.org/10.1016/j.ijcard.2013.06.064.
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    • Schmidt, Márcia M., Renato D. Lopes, L Kristin Newby, Mauro R. Moura, Luciele Stochero, Carlos M. Gottschall, and Alexandre S. Quadros. “Anger control and cardiovascular outcomes..” International Journal of Cardiology 168, no. 4 (October 2013): 4338–39. https://doi.org/10.1016/j.ijcard.2013.05.083.
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    • Sposato, Luciano A., Mariano L. Coppola, Juan Altamirano, Brenda Borrego Guerrero, Jorge Casanova, Maximiliano De Martino, Alejandro Díaz, et al. “Program for the epidemiological evaluation of stroke in Tandil, Argentina (PREVISTA) study: rationale and design..” International Journal of Stroke : Official Journal of the International Stroke Society 8, no. 7 (October 2013): 591–97. https://doi.org/10.1111/ijs.12171.
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    • Hess, Connie N., Sana M. Al-Khatib, Christopher B. Granger, and Renato Lopes. “A review of apixaban for stroke prevention in atrial fibrillation: insights from ARISTOTLE..” Expert Review of Cardiovascular Therapy 11, no. 9 (September 2, 2013): 1105–14. https://doi.org/10.1586/14779072.2013.824181.
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    • Garcia, David A., Lars Wallentin, Renato D. Lopes, Laine Thomas, John H. Alexander, Elaine M. Hylek, Jack Ansell, et al. “Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial..” American Heart Journal 166, no. 3 (September 2013): 549–58. https://doi.org/10.1016/j.ahj.2013.05.016.
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    • Lopes, Renato D., Jennifer A. White, Pierluigi Tricoci, Harvey D. White, Paul W. Armstrong, Eugene Braunwald, Robert P. Giugliano, et al. “Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: insights from the EARLY ACS trial..” International Journal of Cardiology 167, no. 6 (September 2013): 2580–87. https://doi.org/10.1016/j.ijcard.2012.06.053.
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    • Lorga Filho, A. M., A. D. Azmus, A. M. Soeiro, A. S. Quadros, A. Avezum, A. C. Marques, A. Franci, et al. “[Brazilian guidelines on platelet antiaggregants and anticoagulants in cardiology]..” Arquivos Brasileiros De Cardiologia 101, no. 3 Suppl 3 (September 2013): 1–95. https://doi.org/10.5935/abc.2013s009.
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    • Al-Khatib, Sana M., Laine Thomas, Lars Wallentin, Renato D. Lopes, Bernard Gersh, David Garcia, Justin Ezekowitz, et al. “Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial..” European Heart Journal 34, no. 31 (August 2013): 2464–71. https://doi.org/10.1093/eurheartj/eht135.
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    • Gonzalez, M. M., S. Timerman, R. Gianotto-Oliveira, T. F. Polastri, M. F. Canesin, A. Schimidt, A. W. Siqueira, et al. “[First guidelines of the Brazilian Society of Cardiology on Cardiopulmonary Resuscitation and Cardiovascular Emergency Care]..” Arquivos Brasileiros De Cardiologia 101, no. 2 Suppl 3 (August 2013): 1–221. https://doi.org/10.5935/abc.2013s006.
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    • Koshizaka, M., R. D. Lopes, L. K. Newby, P. J. Schulte, R. M. Clare, P. Tricoci, K. W. Mahaffey, H. Ogawa, R. A. Harrington, and J. H. Alexander. “Relationship between diabetes, race, obesity and outcomes in patients with acute coronary syndrome: a pool analysis from randomized trials.” European Heart Journal 34 (August 1, 2013): 787–787.
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    • Lopes, Renato D., Sheila Dickerson, Gail Hafley, Shana Burns, Sandra Tourt-Uhlig, Jennifer White, L Kristin Newby, et al. “Methodology of a reevaluation of cardiovascular outcomes in the RECORD trial: study design and conduct..” American Heart Journal 166, no. 2 (August 2013): 208-216.e28. https://doi.org/10.1016/j.ahj.2013.05.005.
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    • Mahaffey, Kenneth W., Gail Hafley, Sheila Dickerson, Shana Burns, Sandra Tourt-Uhlig, Jennifer White, L Kristin Newby, et al. “Results of a reevaluation of cardiovascular outcomes in the RECORD trial..” American Heart Journal 166, no. 2 (August 2013): 240-249.e1. https://doi.org/10.1016/j.ahj.2013.05.004.
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    • Steinberg, Benjamin A., Sunghee Kim, Jonathan P. Piccini, Gregg C. Fonarow, Renato D. Lopes, Laine Thomas, Michael D. Ezekowitz, et al. “Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry..” Circulation 128, no. 7 (August 2013): 721–28. https://doi.org/10.1161/CIRCULATIONAHA.113.002927.
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    • Cullen, Michael W., Sunghee Kim, Jonathan P. Piccini, Jack E. Ansell, Greg C. Fonarow, Elaine M. Hylek, Daniel E. Singer, et al. “Risks and benefits of anticoagulation in atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry..” Circulation. Cardiovascular Quality and Outcomes 6, no. 4 (July 2013): 461–69. https://doi.org/10.1161/circoutcomes.113.000127.
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    • Lopes, Renato D., Richard C. Becker, L Kristin Newby, Eric D. Peterson, Elaine M. Hylek, Robert Giugliano, Christopher B. Granger, et al. “Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), October 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil..” Journal of Thrombosis and Thrombolysis 36, no. 1 (July 2013): 115–30. https://doi.org/10.1007/s11239-013-0906-z.
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    • Souza Brito, Flavio de, Renato D. Lopes, and John H. Alexander. “The safety and efficacy of apixaban : where do we stand in 2013?.” Expert Opinion on Drug Safety 12, no. 4 (July 2013): 559–67. https://doi.org/10.1517/14740338.2013.799663.
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    • Bahit, Maria Cecilia, Renato D. Lopes, Robert M. Clare, L Kristin Newby, Karen S. Pieper, Frans Van de Werf, Paul W. Armstrong, et al. “Heart failure complicating non-ST-segment elevation acute coronary syndrome: timing, predictors, and clinical outcomes..” Jacc. Heart Failure 1, no. 3 (June 3, 2013): 223–29. https://doi.org/10.1016/j.jchf.2013.02.007.
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    • Giraldez, Roberto R., Robert M. Clare, Renato D. Lopes, Anthony J. Dalby, Dorairaj Prabhakaran, Gerard X. Brogan, Robert P. Giugliano, et al. “Prevalence and clinical outcomes of undiagnosed diabetes mellitus and prediabetes among patients with high-risk non-ST-segment elevation acute coronary syndrome..” American Heart Journal 165, no. 6 (June 2013): 918-925.e2. https://doi.org/10.1016/j.ahj.2013.01.005.
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    • Hijazi, Ziad, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, Christina Christersson, Justin Ezekowitz, Bernard J. Gersh, et al. “N-terminal pro-B-type natriuretic peptide for risk assessment in patients with atrial fibrillation: insights from the ARISTOTLE Trial (Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation)..” Journal of the American College of Cardiology 61, no. 22 (June 2013): 2274–84. https://doi.org/10.1016/j.jacc.2012.11.082.
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    • Leonardi, Sergio, Amanda Stebbins, Renato D. Lopes, Yuliya Lokhnygina, Meredith Todd, Deepak L. Bhatt, Gregg W. Stone, et al. “Quantification of the effect of clopidogrel on enzymatic infarct size related to a percutaneous coronary intervention in patients with acute coronary syndromes: insights from the CHAMPION percutaneous coronary intervention trial..” Coronary Artery Disease 24, no. 4 (June 2013): 321–27. https://doi.org/10.1097/mca.0b013e32835f2fbd.
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    • Nicolau, José C., Ramon Corbalan, Rafael Diaz, Cecilia Bahit, Paul W. Armstrong, Christopher B. Granger, and Renato D. Lopes. “Cardiovascular clinical research in South America..” American Heart Journal 165, no. 6 (June 2013): 848–53. https://doi.org/10.1016/j.ahj.2013.02.004.
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    • Wallentin, Lars, Renato D. Lopes, Michael Hanna, Laine Thomas, Anne Hellkamp, Sunil Nepal, Elaine M. Hylek, et al. “Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation..” Circulation 127, no. 22 (June 2013): 2166–76. https://doi.org/10.1161/circulationaha.112.142158.
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    • Harskamp, Ralf E., Judson B. Williams, Ronald C. Hill, Robbert J. de Winter, John H. Alexander, and Renato D. Lopes. “Saphenous vein graft failure and clinical outcomes: toward a surrogate end point in patients following coronary artery bypass surgery?.” American Heart Journal 165, no. 5 (May 2013): 639–43. https://doi.org/10.1016/j.ahj.2013.01.019.
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    • Harskamp, Ralf E., Renato D. Lopes, Clinton E. Baisden, Robbert J. de Winter, and John H. Alexander. “Saphenous vein graft failure after coronary artery bypass surgery: pathophysiology, management, and future directions..” Annals of Surgery 257, no. 5 (May 2013): 824–33. https://doi.org/10.1097/sla.0b013e318288c38d.
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    • Lopes, Renato D., Christopher B. Granger, and Karen P. Alexander. “The reply..” The American Journal of Medicine 126, no. 5 (May 2013). https://doi.org/10.1016/j.amjmed.2013.01.002.
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    • McMurray, John J. V., Justin A. Ezekowitz, Basil S. Lewis, Bernard J. Gersh, Sean van Diepen, John Amerena, Jozef Bartunek, et al. “Left ventricular systolic dysfunction, heart failure, and the risk of stroke and systemic embolism in patients with atrial fibrillation: insights from the ARISTOTLE trial..” Circulation. Heart Failure 6, no. 3 (May 2013): 451–60. https://doi.org/10.1161/circheartfailure.112.000143.
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    • Guptill, Jeffrey T., Rajendra H. Mehta, Paul W. Armstrong, John Horton, Daniel Laskowitz, Stefan James, Christopher B. Granger, and Renato D. Lopes. “Stroke after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction: timing, characteristics, and clinical outcomes..” Circulation. Cardiovascular Interventions 6, no. 2 (April 2, 2013): 176–83. https://doi.org/10.1161/circinterventions.112.000159.
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    • Rose, Jason J., L Kristin Newby, Samuel Broderick, Karen Chiswell, Frans Van de Werf, Paul W. Armstrong, Kenneth W. Mahaffey, et al. “Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes..” Journal of the American College of Cardiology 61, no. 13 (April 2013): 1461–63. https://doi.org/10.1016/j.jacc.2012.12.032.
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    • Berwanger, Otávio, Luiz Alberto Piva e Mattos, José Fernando Vilela Martin, Renato Delascio Lopes, Estevão Lanna Figueiredo, Daniel Magnoni, Dalton Bertolim Precoma, Carlos Alberto Machado, Jorge Ilha Guimarães, and Jadelson Pinheiro de Andrade. “Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study..” Arquivos Brasileiros De Cardiologia 100, no. 3 (March 2013): 212–20. https://doi.org/10.5935/abc.20130062.
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    • Staico, R., L. Armaganijan, C. Dietrich, A. Abizaid, D. Moreira, R. Lopes, J. Almeida, and M. Franco. “Renal sympathetic ablation using an irrigated-tip catheter: An attractive option?.” Revista Brasileira De Cardiologia Invasiva 21, no. 1 (March 1, 2013).
    • Truffa, Adriano A., Renato D. Lopes, and L Kristin Newby. “Alternatives to warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a look back at the state of the field in 2012..” Postgraduate Medicine 125, no. 2 (March 2013): 146–57. https://doi.org/10.3810/pgm.2013.03.2648.
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    • Lopes, R. D., S. M. Al-Khatib, and L. Wallentin. “Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial (vol 380, pg 1749, 2012).” Lancet 381, no. 9862 (January 19, 2013): 204–204.
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    • Diepen, S. V., L. K. Newby, R. D. Lopes, A. Stebbins, V. Hasselblad, S. James, M. T. Roe, et al. “Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: An APEX AMI substudy.” International Journal of Cardiology 168, no. 3 (2013): 2127–33. https://doi.org/10.1016/j.ijcard.2013.01.004.
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    • Lopes, R. D., S. M. Al-Khatib, and L. Wallentin. “Erratum: Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fi brillation: A secondary analysis of a randomised controlled trial (The Lancet (2012) 380 (1749-58)).” The Lancet 381, no. 9862 (January 1, 2013).
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    • Nicolau, J. C., R. Corbalan, R. Diaz, C. Bahit, P. W. Armstrong, C. B. Granger, and R. D. Lopes. “Cardiovascular clinical research in South America.” American Heart Journal 165, no. 6 (2013): 848–53. https://doi.org/10.1016/j.ahj.2013.02.004.
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    • Eapen, Z. J., R. D. Lopes, S. M. Al-Khatib, Y. Wang, H. Bao, J. Curtis, P. A. Heidenreich, A. F. Hernandez, D. P. Eric, and S. C. Hammill. “Erratum: Are racial/ethnic gaps in the use of cardiac resynchronization therapy narrowing? An analysis of 107,096 patients from the national cardiovascular data registrys ICD registry (Journal of the American College of Cardiology (2012) 60(1577-80)).” Journal of the American College of Cardiology 60, no. 24 (December 18, 2012). https://doi.org/10.1016/j.jacc.2012.10.004.
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    • Cecilia Bahit, Maria, Renato D. Lopes, Stephan H. Hohnloser, Daniel Wojdyla, John H. Alexander, Basil S. Lewis, Philip Aylward, et al. “Apixaban in Patients with Atrial Fibrillation and Prior Coronary Artery Disease: Insights from the ARISTOTLE Trial.” Circulation 126, no. 21 (November 20, 2012).
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    • Hylek, Elaine M., Claes Held, John H. Alexander, Renato D. Lopes, Raffaele DeCaterina, Kurt Huber, Petr Jansky, et al. “Reduction in Bleeding with Apixaban versus Warfarin is Consistent Across Subgroups and Locations: Insights from the ARISTOTLE Trial.” Circulation 126, no. 21 (November 20, 2012).
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    • Hess, Connie N., Richard C. Becker, John H. Alexander, and Renato D. Lopes. “Antithrombotic therapy in heparin-induced thrombocytopenia: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 34, no. 4 (November 2012): 552–61. https://doi.org/10.1007/s11239-012-0785-8.
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    • Hohnloser, Stefan H., Ziad Hijazi, Laine Thomas, John H. Alexander, John Amerena, Michael Hanna, Matyas Keltai, et al. “Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial..” European Heart Journal 33, no. 22 (November 2012): 2821–30. https://doi.org/10.1093/eurheartj/ehs274.
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    • Lopes, Renato D., Sana M. Al-Khatib, Lars Wallentin, Hongqiu Yang, Jack Ansell, M Cecilia Bahit, Raffaele De Caterina, et al. “Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial..” Lancet (London, England) 380, no. 9855 (November 2012): 1749–58. https://doi.org/10.1016/s0140-6736(12)60986-6.
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    • Rao, S. V., D. Dai, S. Subherwal, W. S. Weintraub, R. S. Brindis, J. C. Messenger, R. D. Lopes, and E. D. Peterson. “Erratum: Association between periprocedural bleeding and long-term outcomes following percutaneous coronary intervention in older patients. (JACC: Cardiovascular Interventions (2012) 5 (958-65)).” Jacc: Cardiovascular Interventions 5, no. 11 (November 1, 2012). https://doi.org/10.1016/j.jcin.2012.10.004.
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    • Vavalle, John P., Renato D. Lopes, Anita Y. Chen, L Kristin Newby, Tracy Y. Wang, Bimal R. Shah, P Michael Ho, et al. “Hospital length of stay in patients with non-ST-segment elevation myocardial infarction..” The American Journal of Medicine 125, no. 11 (November 2012): 1085–94. https://doi.org/10.1016/j.amjmed.2012.04.038.
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    • Eapen, Zubin J., Sana Al-Khatib, Renato D. Lopes, Yongfei Wang, Haikun Bao, Jeptha Curtis, Paul A. Heidenreich, Adrian F. Hernandez, Eric D. Peterson, and Stephen C. Hammill. “Are racial/ethnic gaps in the use of cardiac resynchronization therapy narrowing?: an analysis of 107,096 patients from the National Cardiovascular Data Registry's ICD Registry..” Journal of the American College of Cardiology 60, no. 16 (October 2012): 1577–78. https://doi.org/10.1016/j.jacc.2012.06.024.
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    • Quadros, Alexandre S., Eduardo Cambruzzi, Juliana Sebben, Renato B. David, Anibal Abelin, Dulce Welter, Rogério Sarmento-Leite, Rajendra H. Mehta, Carlos A. Gottschall, and Renato D. Lopes. “Red versus white thrombi in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: clinical and angiographic outcomes..” American Heart Journal 164, no. 4 (October 2012): 553–60. https://doi.org/10.1016/j.ahj.2012.07.022.
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    • Roe, Matthew T., Paul W. Armstrong, Keith A. A. Fox, Harvey D. White, Dorairaj Prabhakaran, Shaun G. Goodman, Jan H. Cornel, et al. “Prasugrel versus clopidogrel for acute coronary syndromes without revascularization..” The New England Journal of Medicine 367, no. 14 (October 2012): 1297–1309. https://doi.org/10.1056/nejmoa1205512.
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    • Staico, Rodolfo, Luciana Armaganijan, and Renato D. Lopes. “Coronary embolism and calcified aortic valve: is there a correlation?.” Journal of Thrombosis and Thrombolysis 34, no. 3 (October 2012): 425–27. https://doi.org/10.1007/s11239-012-0710-1.
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    • Diepen, S. van, L. K. Newby, R. D. Lopes, A. Stebbins, V. Hasselblad, S. James, M. T. Roe, et al. “726 Acute Phase Inflammatory Biomarkers Add Little Predictive Value to Clinical Factors Plus NT-proBNP Among Patients With ST-Segment Elevation Myocardial Infarction: An Apex AMI Trial Substudy.” Canadian Journal of Cardiology 28, no. 5 (September 2012): S378–S378. https://doi.org/10.1016/j.cjca.2012.07.657.
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    • Husted, Steen, Stefan James, Richard C. Becker, Jay Horrow, Hugo Katus, Robert F. Storey, Christopher P. Cannon, et al. “Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: a substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial..” Circulation. Cardiovascular Quality and Outcomes 5, no. 5 (September 2012): 680–88. https://doi.org/10.1161/circoutcomes.111.964395.
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    • Lopes, Renato D., Judson B. Williams, Rajendra H. Mehta, Eric M. Reyes, Gail E. Hafley, Keith B. Allen, Michael J. Mack, et al. “Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results..” American Heart Journal 164, no. 3 (September 2012): 379-386.e1. https://doi.org/10.1016/j.ahj.2012.05.019.
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    • Lopes, Renato D., Li Li, Christopher B. Granger, Tracy Y. Wang, JoAnne M. Foody, Marjorie Funk, Eric D. Peterson, and Karen P. Alexander. “Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes..” The American Journal of Medicine 125, no. 9 (September 2012): 897–905. https://doi.org/10.1016/j.amjmed.2012.04.006.
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    • Pesaro, Antonio Eduardo P., Carlos V. Serrano, Marcelo Katz, Alexandre H. Campos, Renato D. Lopes, Luciana C. Marti, Herlon S. Martins, Rodrigo S. Sunahara, Raul C. Maranhão, and José C. Nicolau. “Inflammation and circulating endothelial progenitor cells in patients with coronary artery disease and residual platelet reactivity..” Clinics (Sao Paulo, Brazil) 67, no. 9 (September 2012): 1117–21. https://doi.org/10.6061/clinics/2012(09)21.
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    • Rao, Sunil V., David Dai, Sumeet Subherwal, William S. Weintraub, Ralph S. Brindis, John C. Messenger, Renato D. Lopes, and Eric D. Peterson. “Association between periprocedural bleeding and long-term outcomes following percutaneous coronary intervention in older patients..” Jacc. Cardiovascular Interventions 5, no. 9 (September 2012): 958–65. https://doi.org/10.1016/j.jcin.2012.05.010.
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    • Lopes, Renato D., Sumeet Subherwal, Dajuanicia N. Holmes, Laine Thomas, Tracy Y. Wang, Sunil V. Rao, Erik Magnus Ohman, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “The association of in-hospital major bleeding with short-, intermediate-, and long-term mortality among older patients with non-ST-segment elevation myocardial infarction..” European Heart Journal 33, no. 16 (August 2012): 2044–53. https://doi.org/10.1093/eurheartj/ehs012.
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    • Williams, Judson B., Eric D. Peterson, J Matthew Brennan, Art Sedrakyan, Dale Tavris, John H. Alexander, Renato D. Lopes, et al. “Association between endoscopic vs open vein-graft harvesting and mortality, wound complications, and cardiovascular events in patients undergoing CABG surgery..” Jama 308, no. 5 (August 2012): 475–84. https://doi.org/10.1001/jama.2012.8363.
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    • Diepen, Sean van, Matthew T. Roe, Renato D. Lopes, Amanda Stebbins, Stefan James, L Kristin Newby, David J. Moliterno, et al. “Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial..” Journal of Thrombosis and Thrombolysis 34, no. 1 (July 2012): 106–13. https://doi.org/10.1007/s11239-012-0691-0.
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    • Diepen, Sean van, Petr Widimsky, Renato D. Lopes, Kyle R. White, W Douglas Weaver, Frans Van de Werf, Diego Ardissino, Arnoud W. J. van’t Hof, Paul W. Armstrong, and Christopher B. Granger. “Transfer times and outcomes in patients with ST-segment-elevation myocardial infarction undergoing interhospital transfer for primary percutaneous coronary intervention: APEX-AMI insights..” Circulation. Cardiovascular Quality and Outcomes 5, no. 4 (July 2012): 437–44. https://doi.org/10.1161/CIRCOUTCOMES.112.965160.
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    • Lopes, Renato D., Richard C. Becker, L Kristin Newby, Eric D. Peterson, Elaine M. Hylek, Christopher B. Granger, Mark Crowther, et al. “Highlights from the IV International Symposium of Thrombosis and Anticoagulation (ISTA), October 20-21, 2011, Salvador, Bahia, Brazil..” Journal of Thrombosis and Thrombolysis 34, no. 1 (July 2012): 143–63. https://doi.org/10.1007/s11239-012-0700-3.
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    • Truffa, Adriano A. M., Christopher B. Granger, Kyle R. White, L Kristin Newby, Rajendra H. Mehta, Judith S. Hochman, Manesh R. Patel, et al. “Serious infection after acute myocardial infarction: incidence, clinical features, and outcomes..” Jacc. Cardiovascular Interventions 5, no. 7 (July 2012): 769–76. https://doi.org/10.1016/j.jcin.2012.03.018.
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    • Easton, J Donald, Renato D. Lopes, M Cecilia Bahit, Daniel M. Wojdyla, Christopher B. Granger, Lars Wallentin, Marco Alings, et al. “Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial..” The Lancet. Neurology 11, no. 6 (June 2012): 503–11. https://doi.org/10.1016/s1474-4422(12)70092-3.
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    • James, Stefan K., Robert F. Storey, Nardev S. Khurmi, Steen Husted, Matyas Keltai, Kenneth W. Mahaffey, Juan Maya, et al. “Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack..” Circulation 125, no. 23 (June 2012): 2914–21. https://doi.org/10.1161/circulationaha.111.082727.
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    • Ritt, Luiz E., Antonio Carlos Carvalho, Gilson S. Feitosa, Joel A. Pinho-Filho, Cristiano R. B. Macedo, Fabio Vilas-Boas, Marcus V. S. Andrade, et al. “Heart failure survival score in patients with Chagas disease: correlation with functional variables..” Revista Espanola De Cardiologia (English Ed.) 65, no. 6 (June 2012): 538–43. https://doi.org/10.1016/j.recesp.2011.12.019.
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    • Berwanger, Otávio, Hélio P. Guimarães, Ligia N. Laranjeira, Alexandre B. Cavalcanti, Alessandra A. Kodama, Ana Denise Zazula, Eliana V. Santucci, et al. “Effect of a multifaceted intervention on use of evidence-based therapies in patients with acute coronary syndromes in Brazil: the BRIDGE-ACS randomized trial..” Jama 307, no. 19 (May 2012): 2041–49. https://doi.org/10.1001/jama.2012.413.
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    • Katz, Marcelo, Flavio Tarasoutchi, Antonio Eduardo Pereira Pesaro, Renato D. Lopes, Guilherme Sobreira Spina, Marcelo Luiz Campos Vieira, and Max Grinberg. “Natriuretic peptides and long-term mortality in patients with severe aortic stenosis..” The Journal of Heart Valve Disease 21, no. 3 (May 2012): 331–36.
    • Mehta, Rajendra H., Padma Kaul, Renato D. Lopes, Manesh R. Patel, Yinggan Zheng, Karen S. Pieper, Robert C. Welsh, Paul W. Armstrong, and Christopher B. Granger. “Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI) trial..” American Heart Journal 163, no. 5 (May 2012): 797–803. https://doi.org/10.1016/j.ahj.2012.03.001.
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    • Suarez, Jorge, Jonathan P. Piccini, Li Liang, John J. Atherton, Christopher S. Hayward, Henry Krum, Gregg C. Fonarow, Renato D. Lopes, and Adrian F. Hernandez. “International variation in use of oral anticoagulation among heart failure patients with atrial fibrillation..” American Heart Journal 163, no. 5 (May 2012): 804–11. https://doi.org/10.1016/j.ahj.2012.02.008.
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    • Kociol, R. D., R. D. Lopes, and M. R. Patel. “In reply.” Jama  Journal of the American Medical Association 307, no. 16 (April 25, 2012). https://doi.org/10.1001/jama.2012.531.
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    • Kociol, Robb D., Renato D. Lopes, and Manesh R. Patel. “International Variation in Readmission After Myocardial Infarction Reply.” Jama Journal of the American Medical Association 307, no. 16 (April 25, 2012): 1691–1691. https://doi.org/10.1001/jama.2012.531.
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    • Fosbol, Emil L., Tracy Y. Wang, Shuang Li, Jonathan P. Piccini, Renato D. Lopes, Bimal Shah, Roger M. Mills, et al. “Safety and effectiveness of antithrombotic strategies in older adult patients with atrial fibrillation and non-ST elevation myocardial infarction..” American Heart Journal 163, no. 4 (April 2012): 720–28. https://doi.org/10.1016/j.ahj.2012.01.017.
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    • Berwanger, O., H. P. Guimarães, L. N. Laranjeira, A. B. Cavalcanti, A. A. Kodama, A. D. Zazula, E. V. Santucci, et al. “Effect of a Multifaceted Intervention on Use of Evidence-Based Therapies in Patients With Acute Coronary Syndromes in Brazil: The BRIDGE-ACS Randomized Trial..” Jama, March 25, 2012. https://doi.org/10.1001/jama.2012.413.
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    • Armaganijan, Luciana, Dimpi Patel, Renato D. Lopes, Carlos A. Morillo, Roberta R. N. Araújo, Fernando P. Munhoz, Marcelo A. Puzzi, Murilo J. Carvalho, Lilian B. N. Gallo, and Jeff S. Healey. “Gastroesophageal reflux and atrial fibrillation: is there any correlation?.” Expert Review of Cardiovascular Therapy 10, no. 3 (March 2012): 317–22. https://doi.org/10.1586/erc.11.198.
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    • Berwanger, Otávio, Hélio P. Guimarães, Ligia N. Laranjeira, Alexandre B. Cavalcanti, Alessandra Kodama, Ana Denise Zazula, Eliana Santucci, et al. “A multifaceted intervention to narrow the evidence-based gap in the treatment of acute coronary syndromes: rationale and design of the Brazilian Intervention to Increase Evidence Usage in Acute Coronary Syndromes (BRIDGE-ACS) cluster-randomized trial..” American Heart Journal 163, no. 3 (March 2012): 323-329.e1. https://doi.org/10.1016/j.ahj.2012.02.004.
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    • Subherwal, Sumeet, Eric D. Peterson, Anita Y. Chen, Matthew T. Roe, Jeffrey B. Washam, Brian F. Gage, Richard G. Bach, et al. “Admission international normalized ratio levels, early treatment strategies, and major bleeding risk among non-ST-segment-elevation myocardial infarction patients on home warfarin therapy: insights from the National Cardiovascular Data Registry..” Circulation 125, no. 11 (March 2012): 1414–23. https://doi.org/10.1161/circulationaha.111.059188.
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    • Al-Khatib, Sana M., John H. Alexander, Renato D. Lopes, Kenneth W. Mahaffey, Manesh R. Patel, and Christopher B. Granger. “Promise of factor Xa inhibition in atrial fibrillation..” Current Cardiology Reports 14, no. 1 (February 2012): 70–78. https://doi.org/10.1007/s11886-011-0230-1.
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    • Lopes, Renato D., Rajendra H. Mehta, Gail E. Hafley, Judson B. Williams, Michael J. Mack, Eric D. Peterson, Keith B. Allen, et al. “Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery..” Circulation 125, no. 6 (February 2012): 749–56. https://doi.org/10.1161/CIRCULATIONAHA.111.040311.
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    • Mehta, Rajendra H., Amanda S. Stebbins, Renato D. Lopes, Robert M. Califf, Karen S. Pieper, Paul W. Armstrong, Frans Van de Werf, et al. “Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis..” The American Journal of Cardiology 109, no. 3 (February 2012): 320–26. https://doi.org/10.1016/j.amjcard.2011.09.012.
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    • Kociol, Robb D., Renato D. Lopes, Robert Clare, Laine Thomas, Rajendra H. Mehta, Padma Kaul, Karen S. Pieper, et al. “International variation in and factors associated with hospital readmission after myocardial infarction..” Jama 307, no. 1 (January 2012): 66–74. https://doi.org/10.1001/jama.2011.1926.
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    • Ritt, L. E., A. C. Carvalho, G. S. Feitosa, J. A. Pinho-Filho, C. R. B. MacEdo, F. Vilas-Boas, M. V. S. Andrade, et al. “Heart failure survival score in patients with chagas disease: Correlation with functional variables.” Revista Espanola De Cardiologia 65, no. 6 (January 1, 2012): 538–43. https://doi.org/10.1016/j.recesp.2011.12.019.
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    • Signori, Luis Ulisses, Alexandre Schaan de Quadros, Graciele Sbruzzi, Thiago Dipp, Renato D. Lopes, and Beatriz D’Agord Schaan. “Endothelial function in patients with slow coronary flow and normal coronary angiography..” Clinics 67, no. 6 (January 2012): 677–80. https://doi.org/10.6061/clinics/2012(06)22.
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    • Lopes, Renato D., Bimal R. Shah, DaiWai M. Olson, Xin Zhao, Wenqin Pan, Cheryl D. Bushnell, and Eric D. Peterson. “Antithrombotic therapy use at discharge and 1 year in patients with atrial fibrillation and acute stroke: results from the AVAIL Registry..” Stroke 42, no. 12 (December 2011): 3477–83. https://doi.org/10.1161/strokeaha.111.625392.
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    • Lopes, Renato D., John D. Horowitz, David A. Garcia, Mark A. Crowther, and Elaine M. Hylek. “Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility..” Blood 118, no. 24 (December 2011): 6269–73. https://doi.org/10.1182/blood-2011-08-335612.
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    • Lopes, Renato D., and David A. Garcia. “In people with atrial fibrillation unsuitable for warfarin, apixaban reduces the risk of stroke compared with aspirin, with no difference in major bleeding..” Evidence Based Medicine 16, no. 6 (December 2011): 187–88. https://doi.org/10.1136/ebm.2011.0023.
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    • Cecilia Bahit, Maria, Renato D. Lopes, Robert Clare, Karen S. Pieper, L Kristin Newby, Frans Frans Van de Werf, Paul W. Armstrong, et al. “Heart Failure Occurring at any Time During Hospitalization is Associated with Higher Mortality in Non-ST Elevation-Acute Coronary Syndromes.” Circulation 124, no. 21 (November 22, 2011).
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    • Eapen, Zubin, Sana M. Al-Khatib, Yongfei Wang, Renato D. Lopes, Haikun Bao, Jeptha P. Curtis, Paul A. Heidenreich, Adrian F. Hernandez, and Stephen C. Hammill. “Is Cardiac Resynchronization Therapy Use Improving Among Racial/Ethnic Minorities? An Analysis of 107,096 Patients from the NCDR-ICD Registry.” Circulation 124, no. 21 (November 22, 2011).
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    • Giraldez, Roberto R., Robert Clare, Renato D. Lopes, Anthony J. Dalby, Dorairaj Prabhakaran, Gerald X. Brogan, Robert P. Giugliano, et al. “Undiagnosed Diabetes Mellitus, Pre-Diabetes, and Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes.” Circulation 124, no. 21 (November 22, 2011).
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    • Guptill, Jeffrey T., Renato D. Lopes, Rajendra H. Mehta, John Horton, Daniel Laskowitz, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “Most Strokes Occur More Than 48 Hours Following Primary Percutaneous Coronary Intervention in STEMI: the Stroke Experience in APEX-AMI Trial.” Circulation 124, no. 21 (November 22, 2011).
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    • Kuijt, Wichert J., Mitchell W. Krucoff, Peter Damman, Renato D. Lopes, Cindy L. Green, Karen S. Pieper, Susanna R. Stevens, et al. “Prediction of Myocardial Infarct Size Using Multiple Concomitant Angiographic, Biochemical and Electrocardiographic Biomarkers in Patients with ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention.” Circulation 124, no. 21 (November 22, 2011).
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    • Piccini, Jonathan P., Dajuanicia N. Holmes, Donna M. Ollis, Elizabeth S. Fraulo, Laine Thomas, Jack E. Ansell, Gregg C. Fonarow, et al. “Patterns of Atrial Fibrillation and Treatment Strategies Vary According to Provider Specialty Across Community Practice Settings: Findings From the ORBIT-AF Registry.” Circulation 124, no. 21 (November 22, 2011).
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    • Quadros, Alexandre S., Eduardo Cambruzzi, Renato David, Juliana Sebben, Anibal Abelin, Dulce Welter, Rogerio Sarmento-Leite, Renato D. Lopes, and Carlos A. Gottschall. “Red or White Thrombus in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Does it Matter?.” Circulation 124, no. 21 (November 22, 2011).
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    • Armaganijan, L. V., and R. D. Lopes. “Antithrombotic therapy in patients with ACS and atrial fibrillation: A challenge in clinical practice.” Acute Coronary Syndromes 10, no. 3 (November 17, 2011): 97–102.
    • Alexander, J. H., R. D. Lopes, and L. Wallentin. “The authors reply.” New England Journal of Medicine 365, no. 19 (November 10, 2011): 1844–45. https://doi.org/10.1056/NEJMc1111422.
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    • “Apixaban after Acute Coronary Syndrome.” New England Journal of Medicine 365, no. 19 (November 10, 2011): 1844–45. https://doi.org/10.1056/nejmc1111422.
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    • Horbach, Stevie J., Renato D. Lopes, João C. V. da C Guaragna, Felipe Martini, Rajendra H. Mehta, João B. Petracco, Luis C. Bodanese, et al. “Naproxen as prophylaxis against atrial fibrillation after cardiac surgery: the NAFARM randomized trial..” The American Journal of Medicine 124, no. 11 (November 2011): 1036–42. https://doi.org/10.1016/j.amjmed.2011.07.026.
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    • Piccini, Jonathan P., Elizabeth S. Fraulo, Jack E. Ansell, Gregg C. Fonarow, Bernard J. Gersh, Alan S. Go, Elaine M. Hylek, et al. “Outcomes registry for better informed treatment of atrial fibrillation: rationale and design of ORBIT-AF..” American Heart Journal 162, no. 4 (October 2011): 606-612.e1. https://doi.org/10.1016/j.ahj.2011.07.001.
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    • Granger, Christopher B., John H. Alexander, John J. V. McMurray, Renato D. Lopes, Elaine M. Hylek, Michael Hanna, Hussein R. Al-Khalidi, et al. “Apixaban versus warfarin in patients with atrial fibrillation..” The New England Journal of Medicine 365, no. 11 (September 2011): 981–92. https://doi.org/10.1056/nejmoa1107039.
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    • Lopes, Renato D., Hany Siha, Yuling Fu, Rajendra H. Mehta, Manesh R. Patel, Paul W. Armstrong, and Christopher B. Granger. “Diagnosing acute myocardial infarction in patients with left bundle branch block..” The American Journal of Cardiology 108, no. 6 (September 2011): 782–88. https://doi.org/10.1016/j.amjcard.2011.05.006.
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    • Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Judson B. Williams, Linda K. Shaw, Sean M. O’Brien, Robert M. Califf, G Chad Hughes, and Michael H. Sketch. “Relationship of the time interval between cardiac catheterization and elective coronary artery bypass surgery with postprocedural acute kidney injury..” Circulation 124, no. 11 Suppl (September 2011): S149–55. https://doi.org/10.1161/CIRCULATIONAHA.110.011700.
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    • Alexander, John H., Renato D. Lopes, Stefan James, Rakhi Kilaru, Yaohua He, Puneet Mohan, Deepak L. Bhatt, et al. “Apixaban with antiplatelet therapy after acute coronary syndrome..” The New England Journal of Medicine 365, no. 8 (August 2011): 699–708. https://doi.org/10.1056/nejmoa1105819.
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    • Lopes, Renato D., Richard C. Becker, John H. Alexander, Paul W. Armstrong, Robert M. Califf, Mark Y. Chan, Mark Crowther, et al. “Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil..” Journal of Thrombosis and Thrombolysis 32, no. 2 (August 2011): 242–66. https://doi.org/10.1007/s11239-011-0592-7.
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    • Mehta, R. H., A. Stebbins, R. D. Lopes, R. M. Califf, J. H. Alexander, and C. B. Granger. “Gender paradox: higher incidence but lower one-year mortality with bleeding among women compared with men following fibrinolysis for acute ST-elevation myocardial infarction.” European Heart Journal 32 (August 1, 2011): 166–166.
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    • Mehta, R. H., P. Kaul, R. D. Lopes, M. R. Patel, K. S. Pieper, P. W. Armstrong, and C. B. Granger. “Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the APEX-AMI trial.” European Heart Journal 32 (August 1, 2011): 872–872.
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    • Suarez, Jorge, Jonathan P. Piccini, Li Liang, John J. Atherton, Christopher S. Haywood, Renato D. Lopes, and Adrian F. Hernandez. “International Variation in Use of Anticoagulation among Heart Failure Patients with Atrial Fibrillation.” Journal of Cardiac Failure 17, no. 8 (August 2011): S72–S72. https://doi.org/10.1016/j.cardfail.2011.06.243.
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    • Mehta, Rajendra H., T Bruce Ferguson, Renato D. Lopes, Gail E. Hafley, Michael J. Mack, Nicholas T. Kouchoukos, C Michael Gibson, et al. “Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV trial..” Circulation 124, no. 3 (July 2011): 280–88. https://doi.org/10.1161/CIRCULATIONAHA.110.991299.
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    • Leiria, Tiago L. L., Renato D. Lopes, Judson B. Williams, Jason N. Katz, Renato A. K. Kalil, and John H. Alexander. “Antithrombotic therapies in patients with prosthetic heart valves: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 31, no. 4 (May 2011): 514–22. https://doi.org/10.1007/s11239-011-0574-9.
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    • Leonardi, Sergio, Laine Thomas, Megan L. Koehler, Pierluigi Tricoci, Renato D. Lopes, Harvey D. White, Paul W. Armstrong, and L Kristin Newby. “WHAT THRESHOLD SHOULD BE USED TO DEFINE PERCUTANEOUS CORONARY INTERVENTION-RELATED MYOCARDIAL INFARCTION? AN APPROACH BASED ON CLINICAL RELEVANCE FROM EARLY ACS AND SYNERGY.” Journal of the American College of Cardiology 57, no. 14 (April 2011): E1239–E1239. https://doi.org/10.1016/s0735-1097(11)61239-4.
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    • Lopes, Renato D. “Antiplatelet agents in cardiovascular disease..” Journal of Thrombosis and Thrombolysis 31, no. 3 (April 2011): 306–9. https://doi.org/10.1007/s11239-011-0558-9.
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    • Mehta, Rajendra H., Aijing Z. Starr, Renato D. Lopes, Jonathan P. Piccini, Manesh R. Patel, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “Relationship of sustained ventricular tachyarrhythmias to outcomes in patients undergoing primary percutaneous coronary intervention with varying underlying baseline risk..” American Heart Journal 161, no. 4 (April 2011): 782–89. https://doi.org/10.1016/j.ahj.2011.01.005.
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    • Gharacholou, S Michael, Renato D. Lopes, Karen P. Alexander, Rajendra H. Mehta, Amanda L. Stebbins, Karen S. Pieper, Stefan K. James, Paul W. Armstrong, and Christopher B. Granger. “Age and outcomes in ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: findings from the APEX-AMI trial..” Archives of Internal Medicine 171, no. 6 (March 2011): 559–67. https://doi.org/10.1001/archinternmed.2011.36.
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    • Quadros, Alexandre S., Dulce I. Welter, Fernanda O. Camozzatto, Aurea Chaves, Rajendra H. Mehta, Carlos A. Gottschall, and Renato D. Lopes. “Identifying patients at risk for premature discontinuation of thienopyridine after coronary stent implantation..” The American Journal of Cardiology 107, no. 5 (March 2011): 685–89. https://doi.org/10.1016/j.amjcard.2010.10.045.
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    • Gualandro, Danielle Menosi, Pai Ching Yu, Daniela Calderaro, André C. Marques, Claudio Pinho, Bruno Caramelli, Alina Coutinho Rodrigues Feitosa, et al. “II Guidelines for perioperative evaluation of the Brazilian Society of Cardiology..” Arquivos Brasileiros De Cardiologia 96, no. 3 Suppl 1 (January 2011): 1–68. https://doi.org/10.1590/s0066-782x2011001600001.
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    • Mehta, Rajendra H., Amanda Stebbins, Renato D. Lopes, Sunil V. Rao, Eric R. Bates, Karen S. Pieper, Paul W. Armstrong, et al. “Race, Bleeding, and Outcomes in STEMI Patients Treated with Fibrinolytic Therapy..” The American Journal of Medicine 124, no. 1 (January 2011): 48–57. https://doi.org/10.1016/j.amjmed.2010.07.028.
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    • Stashenko, Gregg, Renato D. Lopes, David Garcia, John H. Alexander, and Victor F. Tapson. “Prophylaxis for venous thromboembolism: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 31, no. 1 (January 2011): 122–32. https://doi.org/10.1007/s11239-010-0522-0.
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    • Armaganijan, L, Lopes, RD, Healey, JS, Piccini, JP, Nair, GM, and Morillo, CA. "Do omega-3 fatty acids prevent atrial fibrillation after open heart surgery? A meta-analysis of randomized controlled trials." Clinics 66, no. 11 (January 2011): 1923-1928. (Review)  Full Text
    • Chan, Mark Y., Jie L. Sun, Tracy Y. Wang, Renato D. Lopes, Marc E. Jolicoeur, Karen S. Pieper, Sunil V. Rao, et al. “Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: a pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY..” American Heart Journal 160, no. 6 (December 2010): 1056-1064.e2. https://doi.org/10.1016/j.ahj.2010.09.001.
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    • Garcia, David A., Renato D. Lopes, and Elaine M. Hylek. “New-onset atrial fibrillation and warfarin initiation: high risk periods and implications for new antithrombotic drugs..” Thrombosis and Haemostasis 104, no. 6 (December 2010): 1099–1105. https://doi.org/10.1160/th10-07-0491.
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    • Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Linda K. Shaw, Donald D. Glower, Robert A. Harrington, Robert M. Califf, and Michael H. Sketch. “Impact of recovery of renal function on long-term mortality after coronary artery bypass grafting..” The American Journal of Cardiology 106, no. 12 (December 2010): 1728–34. https://doi.org/10.1016/j.amjcard.2010.07.045.
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    • Leonardi, Sergio, Amanda Stebbins, Renato D. Lopes, Yuliya Lokhnygina, Deepak L. Bhatt, Gregg W. Stone, Michael A. Lincoff, et al. “Pre-Treatment With Thienopyridines Reduces The Amount of Myonecrosis in Acute Coronary Syndrome Patients Invasively Managed: Insights from the CHAMPION trials.” Circulation 122, no. 21 (November 23, 2010).
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    • Lopes, Renato D., Jennifer A. White, Pierluigi Tricoci, Harvey D. White, Paul W. Armstrong, Eugene Braunwald, Robert P. Giugliano, et al. “More Bleeding but No Additional Efficacy with Increasing Age in High-risk ACS Patients Treated with Early vs. Delayed, Provisional Eptifibatide.” Circulation 122, no. 21 (November 23, 2010).
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    • Lopes, Renato D., Li Li, Christopher B. Granger, Tracy Y. Wang, JoAnne M. Foody, Marjorie Funk, Eric D. Peterson, and Karen P. Alexander. “Discharge Warfarin is Underused in High Risk Atrial Fibrillation Patients With Myocardial Infarction.” Circulation 122, no. 21 (November 23, 2010).
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    • Kong, Melissa H., Renato D. Lopes, Jonathan P. Piccini, Vic Hasselblad, Tristram D. Bahnson, and Sana M. Al-Khatib. “Surgical Maze procedure as a treatment for atrial fibrillation: a meta-analysis of randomized controlled trials..” Cardiovascular Therapeutics 28, no. 5 (October 2010): 311–26. https://doi.org/10.1111/j.1755-5922.2010.00139.x.
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    • Flato, Uri Adrian Prync, Hélio Penna Guimarães, Renato Delascio Lopes, Jorge Luís Valiatti, Elias Marcos Silva Flato, and Ricardo Gonçalves Lorenzo. “Usefulness of Extended-FAST (EFAST-Extended Focused Assessment with Sonography for Trauma) in critical care setting..” Revista Brasileira De Terapia Intensiva 22, no. 3 (September 2010): 291–99.
    • Batista, M. L., R. D. Lopes, M. C. L. Seelaender, and A. C. Lopes. “Anti-inflammatory effect of physical training in heart failure: Role of TNF-α and IL-10 (Arquivos Brasileiros de Cardiologia (2009) 93, 6, (692-700)).” Arquivos Brasileiros De Cardiologia 95, no. 2 (August 1, 2010). https://doi.org/10.1590/S0066-782X2010001200022.
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    • Lopes, R. D., M. L. Batista, J. C. Rosa, F. S. De Lira, E. Martins, A. Y. Shimura, P. C. Brum, A. H. Lancha, M. C. L. Seelaender, and A. C. Lopes. “Changes in the production of IL-10 and TNF-α in skeletal muscle of rats with heart failure secondary to acute myocardial infarction (Arquivos Brasileiros de Cardiologia (2010) 94, 3, (313-320)).” Arquivos Brasileiros De Cardiologia 95, no. 2 (August 1, 2010). https://doi.org/10.1590/S0066-782X2010001200023.
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    • Diepen, Sean van, Hany Siha, Yuling Fu, Cynthia M. Westerhout, Renato D. Lopes, Christopher B. Granger, Paul W. Armstrong, and Paul W. APEX AMI Investigators. “Do baseline atrial electrocardiographic and infarction patterns predict new-onset atrial fibrillation after ST-elevation myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction Trial..” Journal of Electrocardiology 43, no. 4 (July 2010): 351–58. https://doi.org/10.1016/j.jelectrocard.2010.04.001.
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    • Piccini, Jonathan P., Renato D. Lopes, and Kenneth W. Mahaffey. “Oral factor Xa inhibitors for the prevention of stroke in atrial fibrillation..” Current Opinion in Cardiology 25, no. 4 (July 2010): 312–20. https://doi.org/10.1097/hco.0b013e32833a524f.
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    • Lopes, Renato D., Eric D. Peterson, Anita Y. Chen, Matthew T. Roe, Tracy Y. Wang, E Magnus Ohman, David J. Magid, et al. “Antithrombotic strategy in non-ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: insights from the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry..” Jacc. Cardiovascular Interventions 3, no. 6 (June 2010): 669–77. https://doi.org/10.1016/j.jcin.2010.03.015.
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    • Gharacholou, S Michael, Renato D. Lopes, Jeffrey B. Washam, L Kristin Newby, Stefan K. James, and John H. Alexander. “Antithrombotic therapy in acute coronary syndromes: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 29, no. 4 (May 2010): 516–28. https://doi.org/10.1007/s11239-009-0437-9.
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    • Lopes, Renato D., David Garcia, Richard C. Becker, Christopher B. Granger, L Kristin Newby, John H. Alexander, E Marc Jolicoeur, et al. “Highlights from the II International Symposium of Thrombosis and Anticoagulation (ISTA), October 22-23, 2009, São Paulo, Brazil..” Journal of Thrombosis and Thrombolysis 29, no. 4 (May 2010): 395–408. https://doi.org/10.1007/s11239-010-0454-8.
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    • Krishnan, Anandi, Renato D. Lopes, John H. Alexander, Richard C. Becker, and Larry B. Goldstein. “Antithrombotic therapy for ischemic stroke: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 29, no. 3 (April 2010): 368–77. https://doi.org/10.1007/s11239-010-0439-7.
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    • Lopes, Renato D., John H. Alexander, Sana M. Al-Khatib, Jack Ansell, Raphael Diaz, J Donald Easton, Bernard J. Gersh, et al. “Apixaban for reduction in stroke and other ThromboemboLic events in atrial fibrillation (ARISTOTLE) trial: design and rationale..” American Heart Journal 159, no. 3 (March 2010): 331–39. https://doi.org/10.1016/j.ahj.2009.07.035.
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    • Lopes, Renato Delacio, Miguel Luiz Batista, José Cesar Rosa, Fabio Santos de Lira, Eivor Martins, Alex Yamashita Shimura, Patrícia Chakur Brum, Antonio Herbert Lancha, Marília C. L. Seelaender, and Antonio Carlos Lopes. “Changes in the production of IL-10 and TNF-alpha in skeletal muscle of rats with heart failure secondary to acute myocardial infarction..” Arquivos Brasileiros De Cardiologia 94, no. 3 (March 2010): 293–320. https://doi.org/10.1590/s0066-782x2010000300006.
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    • Lopes, Renato D., Aijing Starr, Carl F. Pieper, Sana M. Al-Khatib, L Kristin Newby, Rajendra H. Mehta, Frans Van de Werf, et al. “Warfarin use and outcomes in patients with atrial fibrillation complicating acute coronary syndromes..” The American Journal of Medicine 123, no. 2 (February 2010): 134–40. https://doi.org/10.1016/j.amjmed.2009.09.015.
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    • Batista, M. L., J. C. Rosa, R. D. Lopes, F. S. Lira, E. Martins, A. S. Yamashita, P. C. Brum, A. H. Lancha, A. C. Lopes, and M. Seelaender. “Exercise training changes IL-10/TNF-alpha ratio in the skeletal muscle of post-MI rats..” Cytokine 49, no. 1 (January 2010): 102–8. https://doi.org/10.1016/j.cyto.2009.10.007.
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    • Lopes, Renato D., and Christopher B. Granger. “Interpreting the TRITON results in light of the event adjudication process..” Cardiology 115, no. 2 (January 2010): 89–90. https://doi.org/10.1159/000256383.
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    • Mehta, Rajendra H., Renato D. Lopes, Andrea Ballotta, Alessandro Frigiola, Michael H. Sketch, Eduardo Bossone, and Eric R. Bates. “Percutaneous coronary intervention or coronary artery bypass surgery for cardiogenic shock and multivessel coronary artery disease?.” American Heart Journal 159, no. 1 (January 2010): 141–47. https://doi.org/10.1016/j.ahj.2009.10.035.
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    • Batista, Miguel Luiz, Renato Delascio Lopes, Marília Cerqueira Leite Seelaender, and Antonio Carlos Lopes. “Anti-inflammatory effect of physical training in heart failure: role of TNF-alpha and IL-10..” Arquivos Brasileiros De Cardiologia 93, no. 6 (December 2009): 643–700.
    • Júnior, M. L. B., R. D. Lopes, M. C. L. Seelaender, and A. C. Lopes. “Antiinflammatory effect of physical training in heart failure: Role of TNF-α and IL-10.” Arquivos Brasileiros De Cardiologia 93, no. 6 (December 1, 2009).
    • Lopes, R. D., and C. B. Granger. “β-blockers in myocardial infarction: An overview.” Acute Coronary Syndromes 9, no. 4 (December 1, 2009): 141–47.
    • Lopes, R. D., and C. B. Granger. “Highlights from the American Heart Association (AHA) Scientific Sessions 2008.” Acute Coronary Syndromes 9, no. 3 (December 1, 2009): 121–24.
    • Piccini, Jonathan P., Renato D. Lopes, Melissa H. Kong, Vic Hasselblad, Kevin Jackson, and Sana M. Al-Khatib. “Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials..” Circulation. Arrhythmia and Electrophysiology 2, no. 6 (December 2009): 626–33. https://doi.org/10.1161/circep.109.856633.
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    • Lopes, R. D., J. H. Alexander, and T. B. Ferguson. “The authors reply.” New England Journal of Medicine 361, no. 19 (November 5, 2009): 1909–10.
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    • Lopes, Renato D., John H. Alexander, and T Bruce Ferguson. “Endoscopic versus Open Vein-Graft Harvesting REPLY.” New England Journal of Medicine 361, no. 19 (November 5, 2009): 1909–10.
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    • Lopes, Renato D., E Magnus Ohman, Christopher B. Granger, Emily F. Honeycutt, Kevin J. Anstrom, Peter B. Berger, Eric M. Crespo, et al. “Six-month follow-up of patients with in-hospital thrombocytopenia during heparin-based anticoagulation (from the Complications After Thrombocytopenia Caused by Heparin [CATCH] registry)..” The American Journal of Cardiology 104, no. 9 (November 2009): 1285–91. https://doi.org/10.1016/j.amjcard.2009.06.045.
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    • Houman Fekrazad, M., Renato D. Lopes, Gregg J. Stashenko, John H. Alexander, and David Garcia. “Treatment of venous thromboembolism: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 28, no. 3 (October 2009): 270–75. https://doi.org/10.1007/s11239-009-0374-7.
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    • Lopes, Renato D., and Karen P. Alexander. “Antiplatelet therapy in older adults with non-ST-segment elevation acute coronary syndrome: considering risks and benefits..” The American Journal of Cardiology 104, no. 5 Suppl (September 2009): 16C-21C. https://doi.org/10.1016/j.amjcard.2009.06.021.
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    • Lopes, Renato D., Laine E. Elliott, Harvey D. White, Judith S. Hochman, Frans Van de Werf, Diego Ardissino, Torsten T. Nielsen, et al. “Antithrombotic therapy and outcomes of patients with atrial fibrillation following primary percutaneous coronary intervention: results from the APEX-AMI trial..” European Heart Journal 30, no. 16 (August 2009): 2019–28. https://doi.org/10.1093/eurheartj/ehp213.
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    • Kraai, Erik P., Renato D. Lopes, John H. Alexander, and David Garcia. “Perioperative management of anticoagulation: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 28, no. 1 (July 2009): 16–22. https://doi.org/10.1007/s11239-009-0313-7.
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    • Lopes, Renato D., Gail E. Hafley, Keith B. Allen, T Bruce Ferguson, Eric D. Peterson, Robert A. Harrington, Rajendra H. Mehta, et al. “Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery..” The New England Journal of Medicine 361, no. 3 (July 2009): 235–44. https://doi.org/10.1056/nejmoa0900708.
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    • Lopes, Renato D., Richard C. Becker, David Garcia, Elaine M. Hylek, Christopher B. Granger, Dayse M. Lourenço, Helena B. Nader, et al. “Highlights from the I international symposium of thrombosis and anticoagulation in internal medicine, October 23-25, 2008, Sao Paulo, Brazil..” Journal of Thrombosis and Thrombolysis 28, no. 1 (July 2009): 106–16. https://doi.org/10.1007/s11239-009-0324-4.
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    • Mehta, Rajendra H., Aijing Z. Starr, Renato D. Lopes, Judith S. Hochman, Petr Widimsky, Karen S. Pieper, Paul W. Armstrong, Christopher B. Granger, and Christopher B. APEX AMI Investigators. “Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention..” Jama 301, no. 17 (May 2009): 1779–89. https://doi.org/10.1001/jama.2009.600.
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    • Kong, Melissa H., Renato D. Lopes, Jonathan P. Piccini, Vic Hasselblad, Tristram D. Bahnson, and Sana M. Al-Khatib. “Surgical Maze Procedure as a Treatment for Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A118–A118.
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    • Lopes, Renato D., Aijing Starr, Sana M. Al-Khatib, L Kristin Newby, Rajendra H. Mehta, Frans Van de Werf, Kenneth W. Mahaffey, et al. “Warfarin Is Independently Associated With Lower Risk of Six-Month Death or Myocardial Infarction in Patients With Atrial Fibrillation Following Acute Coronary Syndromes.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A354–A354.
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    • Lopes, Renato D., Hany Siha, Yuling Fu, Paul W. Armstrong, and Christopher B. Granger. “Left Bundle Branch Block Without Concordant ST-Elevation In Suspected ST-Elevation Myocardial Infarction Identifies Patients With High False Positive Rates: Insights From the APEX-AMI Trial.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A323–A323.
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    • Feitosa-Filho, Gilson Soares, Joberto Pinheiro Sena, Hélio Penna Guimarães, and Renato Delascio Lopes. “Therapeutical hypothermia after cardiopulmonary resuscitation: evidences and practical issues..” Revista Brasileira De Terapia Intensiva 21, no. 1 (March 2009): 65–71.
    • Lira, Fábio S., José C. Rosa, Nelo E. Zanchi, Alex S. Yamashita, Renato D. Lopes, Antonio C. Lopes, Miguel L. Batista, and Marília Seelaender. “Regulation of inflammation in the adipose tissue in cancer cachexia: effect of exercise..” Cell Biochemistry and Function 27, no. 2 (March 2009): 71–75. https://doi.org/10.1002/cbf.1540.
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    • Lopes, Renato D., Karen P. Alexander, Steven V. Manoukian, Michel E. Bertrand, Frederick Feit, Harvey D. White, Charles V. Pollack, et al. “Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial..” Journal of the American College of Cardiology 53, no. 12 (March 2009): 1021–30. https://doi.org/10.1016/j.jacc.2008.12.021.
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    • Belfort, Rubens N., Bruno F. Fernandes, André Romano, Ricardo Nose, Jonathan Cools-Lartigue, Eduardo V. Navajas, Garles Mm Vieira, Renato Delascio Lopes, and Rubens Belfort. “Bilateral macular hemorrhage as a complication of drug-induced anemia: a case report..” Journal of Medical Case Reports 3 (January 13, 2009). https://doi.org/10.1186/1752-1947-3-16.
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    • Lópes, R. D., M. Chan, and L. K. Newby. “Novel Markers in Patients with Suspected Acute Coronary Syndromes,” January 13, 2009, 75–92. https://doi.org/10.1002/9781444300208.ch5.
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    • Lopes, R. D., E. M. Jolicoeur, and M. Y. Chan. “Hyporesponsivity to antiplatelet therapy.” Revista Brasileira De Cardiologia Invasiva 17, no. 4 (January 1, 2009): 450–52.
    • Lopes, Renato D., Jonathan P. Piccini, Elaine M. Hylek, Christopher B. Granger, and John H. Alexander. “Antithrombotic therapy in atrial fibrillation: guidelines translated for the clinician..” Journal of Thrombosis and Thrombolysis 26, no. 3 (December 2008): 167–74. https://doi.org/10.1007/s11239-008-0272-4.
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    • Lopes, Renato D., Christopher B. Granger, Emily F. Honeycutt, Eric M. Crespo, Kevin J. Anstrom, E Magnus Ohman, and Richard C. Becker. “Patients with Thrombocytopenia following Heparin Therapy Have Early but not Late Risk of Death: Results from the CATCH Registry.” Circulation 118, no. 18 (October 28, 2008): S1052–S1052.
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    • Mehta, Rajendra H., Aijing Z. Starr, Renato D. Lopes, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “Association of Sustained Ventricular Tachycardia/Fibrillation and the Timing of its Occurrence on Outcomes in Patients Undergoing Primary Percutaneous Coronary Interventions: Insights from the APEX-AMI Trial.” Circulation 118, no. 18 (October 28, 2008): S1058–S1058.
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    • Lopes, R. D., G. E. Hafley, K. B. Allen, T. B. Ferguson, E. D. Peterson, R. A. Harrington, N. T. Kouchoukos, C. M. Gibson, and J. H. Alexander. “Endoscopic vein harvesting is a strong independent predictor of vein graft failure in patients undergoing coronary artery bypass graft surgery.” European Heart Journal 29 (September 1, 2008): 284–85.
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    • Lopes, Renato D., Karen P. Alexander, Gretchen Marcucci, Harvey D. White, Sarah Spinler, Jacques Col, Philip E. Aylward, Robert M. Califf, and Kenneth W. Mahaffey. “Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial..” European Heart Journal 29, no. 15 (August 2008): 1827–33. https://doi.org/10.1093/eurheartj/ehn236.
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    • Lopes, R. D., K. S. Pieper, J. R. Horton, S. M. Al-Khatib, L. K. Newby, R. H. Mehta, F. Van de Werf, et al. “Short- and long-term outcomes following atrial fibrillation in patients with acute coronary syndromes with or without ST-segment elevation..” Heart (British Cardiac Society) 94, no. 7 (July 2008): 867–73. https://doi.org/10.1136/hrt.2007.134486.
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    • Lopes, R. D., M. Chan, C. Melloni, E. M. Jolicoeur, L. A. Allen, B. R. Shah, J. N. Katz, J. S. Berger, and J. P. Piccini. “Late-breaking trials summary from the 2008 American College of Cardiology Scientific Sessions, March 29 to April 1, Chicago, IL.” American Heart Journal 156, no. 1 (July 1, 2008): 7–12. https://doi.org/10.1016/j.ahj.2008.04.008.
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    • Allen, Larry A., E Marc Jolicoeur, Chiara Melloni, Renato D. Lopes, Mark Y. Chan, Mohamed Majidi, Jonathan P. Piccini, Jeffrey S. Berger, Jason N. Katz, and Bimal R. Shah. “Highlights from American Heart Association, November 4-7, 2007, Orlando, Florida, USA. Late-breaking trials summary..” American Heart Journal 155, no. 4 (April 2008): 615–23. https://doi.org/10.1016/j.ahj.2007.12.001.
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    • Batista, Miguel Luiz, Ronaldo V. T. Santos, Renato D. Lopes, Antônio C. Lopes, Luís Fernando B. P. Costa Rosa, and Marília C. L. Seelaender. “Endurance training modulates lymphocyte function in rats with post-MI CHF..” Medicine and Science in Sports and Exercise 40, no. 3 (March 2008): 549–56. https://doi.org/10.1249/mss.0b013e31815ed6d2.
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    • Batista, Mariana Dias, Daniela Takano, Renato Delascio Lopes, Milvia M. S. S. Enokihara, Nilceo Schwery Michalany, and Fernando Augusto de Almeida. “Paraneoplastic pemphigus associated with non-Hodgkin lymphoma..” Dermatology Online Journal 14, no. 6 (January 2008).
    • Lopes, Renato D., Kenneth Mahaffey, Robert A. Harrington, John Horton, Paul Armstrong, Kristin Newby, Magnus Ohman, et al. “Atrial fibrillation is independently associated with a high risk of death in patients with acute coronary syndromes.” Circulation 116, no. 16 (October 16, 2007): 315–315.
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    • Jolicoeur, E Marc, Tracy Wang, Renato D. Lopes, and E Magnus Ohman. “Percutaneous coronary interventions in patients with heparin-induced thrombocytopenia..” Current Cardiology Reports 9, no. 5 (September 2007): 396–405. https://doi.org/10.1007/bf02938367.
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    • Lopes, R. D., G. Marcucci, H. D. White, S. A. Spinler, J. Col, D. C. Gulba, P. E. Aylward, R. M. Califf, J. J. Ferguson, and K. W. Mahaffey. “Similar association between age and outcomes in high-risk ACS patients treated with enoxaparin or unfractionated heparin.” European Heart Journal 28 (September 1, 2007): 218–218.
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    • Lopes, R. D., K. M. Mahaffey, R. H. Harrington, L. L. Lan, P. A. Armstrong, K. N. Newby, M. O. Ohman, F. V. W. Van de Werf, S. A. K. Al-Khatib, and C. B. G. Granger. “Atrial fibrillation is associated with worse outcomes in ST elevation and non ST elevation acute coronary syndromes.” European Heart Journal 28 (September 1, 2007): 259–60.
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    • Adams, George L., James S. Mills, Chiara Melloni, Larry A. Allen, E Marc Jolicoeur, Tracy Wang, Mark Chan, Mohamed Majidi, and Renato D. Lopes. “Highlights from the 56th annual scientific sessions of the American College of Cardiology: March 25 to 27, 2007, Atlanta, Georgia..” American Heart Journal 154, no. 2 (August 2007): 247–59. https://doi.org/10.1016/j.ahj.2007.05.005.
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    • Lopes, Renato Delascio, Lindalva Batista Neves, Vânia D’Almeida, Gleice Margarete de Souza Conceição, and Alexandre Gabriel. “Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus..” Arquivos Brasileiros De Cardiologia 88, no. 4 (April 2007): 424–29. https://doi.org/10.1590/s0066-782x2007000400010.
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    • Lopes, R. D., L. B. Neves, V. D’Almeida, G. M. D. S. Conceição, and A. G. Jr. “Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus.” Arquivos Brasileiros De Cardiologia 88, no. 4 (2007).
    • Hira, A. Y., A. Nebel de Mello, R. A. Faria, V. Odone Filho, R. D. Lopes, and M. K. Zuffo. “Development of a telemedicine model for emerging countries: a case study on pediatric oncology in Brazil..” Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference 1 (January 2006): 5252–56. https://doi.org/10.1109/iembs.2006.259380.
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    • Santos, Ina S., Jose Boccio, Ari S. Santos, Neiva C. J. Valle, Camila S. Halal, Marta Colvara Bachilli, and Ricardo D. Lopes. “Prevalence of Helicobacter pylori infection and associated factors among adults in Southern Brazil: a population-based cross-sectional study..” Bmc Public Health 5 (January 2005). https://doi.org/10.1186/1471-2458-5-118.
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    • Góes, V. P., L. S. Machado, M. C. Cabral, R. B. Leitão, R. D. Lopes, and M. K. Zuffo. “Interactive stereoscopic full-color direct volume visualization for virtual reality applications in medicine..” Studies in Health Technology and Informatics 81 (January 2001): 161–67.
    • Machado, L. S., A. N. de Mello, R. D. Lopes, V. Odone Filho, and M. K. Zuffo. “A virtual reality simulator for bone marrow harvest for pediatric transplant..” Studies in Health Technology and Informatics 81 (January 2001): 293–97.
    • Liberatori Filho, A. W., R. D. Lopes, O. A. Mora, M. J. Simões, and A. C. Lopes. “[Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats]..” Revista Da Associacao Medica Brasileira (1992) 45, no. 3 (July 1999): 242–46. https://doi.org/10.1590/s0104-42301999000300009.
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  • Book Sections

    • De Carvalho, A. C. C., R. D. Lopes, and A. A. V. de Paola. “Atrial fibrillation and stroke prevention.” In Prevention of Cardiovascular Diseases: From Current Evidence to Clinical Practice, 261–76, 2015. https://doi.org/10.1007/978-3-319-22357-5_25.
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    • Berwanger, O., A. Biasi, and R. D. Lopes. “Designing Clinical Trials in Cardiology.” In Intensive Care in Cardiology, edited by E. Knobel. Atheneu, 2015.
    • Brito, F. S., and R. D. Lopes. “Antithrombotic Therapy in Cardiology.” In Intensive Care in Cardiology, edited by E. Knobel. Atheneu, 2015.
    • Lopes, R. D. “Antithrombotic Therapy in Atrial Fibrillation.” In Intensive Care in Cardiology, edited by E. Knobel. Atheneu, 2015.
    • Pesaro, A. E. P., and R. D. Lopes. “Non-ST Elevation Acute Coronary Syndrome.” In Intensive Care in Cardiology, edited by E. Knobel. Atheneu, 2015.
    • Barros e Silva, P. G. M., and R. D. Lopes. “Cardiac Cycle and Importance of Physical Examination.” In Cardiology, edited by MdCV Moreira, S. T. Montenegro, and A. A. de Paola. Manole: Brazilian Society of Cardiology, 2014.
    • Brito, F. S., R. D. Lopes, and M. T. Roe. “Atherothrombosis.” In Clinical Practice, edited by D. L. Bhatt. Oxford American Cardiovascular Library, 2013.
    • Reist, C. J., T. L. Rorick, L. G. Berdan, and R. D. Lopes. “The Role of Academic Research Organizations in Clinical Research.” In Understanding Clinical Trials, edited by R. D. Lopes and R. A. Harrington. New York: McGraw-Hill, 2013.
    • Lopes, R. D., M. Chan, and L. K. Newby. “Novel Markers in Patients with Suspected ACS.” In Biomarkers in Heart Disease, edited by J. A. De Lemos. American Heart Association, 2008.
    • Lopes, A. C., and R. D. Lopes. “Arterial High Blood Pressure.” In Emergency Medicine Manual, edited by A. C. Lopes, M. ElenaGuariento, and L. Ward. Editora Atheneu, 2006.
    • Lopes, R. D., and H. P. Guimaraes. “Acid-base and Hydro-electrolytic Balance.” In Clinical Toxicology Fundamentals, edited by S. Graff and A. C. Lopes. Editora Atheneu, 2006.
    • Almeida, C. E. S., R. D. Lopes, and H. P. Guimaraes. “Introduction.” In Acid-Base and Hydro-Electrolytic Balance, 3–11. Editora Atheneu, 2005.
    • Costa, M. P. F., H. P. Guimaraes, and R. D. Lopes. “Defibrillation and Electric.” In Cardio Respiratory Stroke, 65–73. Editora Atheneu, 2005.
    • Feitosa Filho, G. S., and R. D. Lopes. “Therapeutic Hypothermia in Brain-Cardio Pulmonary Resuscitation.” In Cardio Respiratory Stroke, 105–12. Editora Atheneu, 2005.
    • Fonsecca, M. A. J., R. D. Lopes, and F. R. B. Marques. “Crucial Algorithms to the Assistance to Cardio Respiratory Stroke.” In Cardio Respiratory Stroke, 161–64. Editora Atheneu, 2005.
    • Gomes, E. P., V. N. Siqueira, and R. D. Lopes. “Asystole.” In Cardio Respiratory Stroke, 43–48. Editora Atheneu, 2005.
    • Guimaraes, H. P., N. Filgueiras, and R. D. Lopes. “Cardio Pulmonary and Brain Resuscitation.” In Introduction to Intensive Medicine, edited by H. P. Guimaraes and A. M. D. A. Ferreira, 1:9–34. Sao Paulo, Brazil, 2005.
    • Guimaraes, H. P., R. D. Lopes, L. F. R. Falcão, and L. E. J. Segovia. “Definition, Levels of Evidence and Diagnosis.” In Cardio Respiratory Stroke, 1–5. Editora Atheneu, 2005.
    • Guimaraes, H. P., R. D. Lopes, and G. K. Barcelos. “Internal and Transvein Pacemaker.” In Cardio Respiratory Stroke, 91–97. Editora Atheneu, 2005.
    • Guimaraes, H. P., R. D. Lopes, and M. P. Costa. “Basic Life Support (SBV).” In Cardio Respiratory Stroke, 7–35. Editora Atheneu, 2005.
    • Guimaraes, H. P., and R. D. Lopes. “Cardio Pulmonary Evaluation previous to exercises.” In The Exercise as Therapy in Practical Medicine, edited by M. Vaisberg, F. B. P. C. Rosa, and M. T. de Mello, 1:27–35. Sao Paulo, Brazil, 2005.
    • Lopes, R. D. “Conclusion.” In Acid-Base and Hydro-Electrolytic Balance, 79–79. Editora Atheneu, 2005.
    • Lopes, R. D., M. J. B. Silva, and V. L. D. Rego. “Primary Disturbances.” In Acid-Base and Hydro-Electrolytic Balance, 13–54. Editora Atheneu, 2005.
    • Lopes, R. D., V. L. D. Rego, and M. J. B. Silva. “Clinical Cases.” In Acid-Base and Hydro-Electrolytic Balance, 69–78. Editora Atheneu, 2005.
    • Lopes, R. D., and H. P. Guimaraes. “Ventricular Fibrillation (FV) and Ventricular Palpitation (TV) without Pulse.” In Cardio Respiratory Stroke, 37–42. Editora Atheneu, 2005.
    • Rego, V. L. D., and R. D. Lopes. “Secondary Disturbances (compensations) and Mixed.” In Acid-Base and Hydro-Electrolytic Balance, 55–59. Editora Atheneu, 2005.
    • Silva, M. J. B., R. D. Lopes, and H. P. Guimaraes. “Systematic Approach of the Acid – base disturbances and Arterial Gas.” In Acid-Base and Hydro-Electrolytic Balance, 61–67. Editora Atheneu, 2005.
    • Siqueira, V. N., J. S. Mossini, H. P. Guimaraes, and R. D. Lopes. “Drug Doses and Administration Modes.” In Cardio Respiratory Stroke, 165–73. Editora Atheneu, 2005.
    • Lopes, A. C., A. W. Liberatori Filho, and R. D. Lopes. “Non- Toxic High Blood Pressure Treatment during pregnancy,” 171–75. Sao Paulo, Brazil: Medsi Editora Medica Cientifica Ltda, 2003.
    • Lopes, A. C., R. D. Lopes, and A. W. Liberatori Filho. “Definition of Critical Pneumonia Acquired and Therapeutic Orientation for the Community.” In Medical Practice Topics, 235–36. São Paulo, Brazil: Medsi Editora Médica e Cientifica Ltda, 2003.

  • Other Articles

    • Castleberry, Anthony W., Judson B. Williams, Mani A. Daneshmand, Emily Honeycutt, Linda K. Shaw, Zainab Samad, Renato D. Lopes, et al. “Response to letter regarding article, "surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience"..” Circulation, March 2015. https://doi.org/10.1161/CIRCULATIONAHA.114.013125.
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  • Reports

    • Al-Khatib, S. M., N. Allen LaPointe, R. Chatterjee, M. J. Crowley, M. E. Dupre, D. F. Kong, R. D. Lopes, et al. “Treatment of Atrial Fibrillation. Comparative Effectiveness Review 119.” Treatment of Atrial Fibrillation. Comparative Effectiveness Review 119. Rockville, MD: AHRQ Publication, June 28, 2013.

  • Conference Papers

    • Leonardi, Sergio, Renato D. Lopes, Ph Gabriel Steg, Freddy Abnousi, Alberto Menozzi, Jayne Prats, Stacey Mangum, et al. “Implications of different criteria for percutaneous coronary intervention-related myocardial infarction on study results of three large phase III clinical trials: The CHAMPION experience..” In European Heart Journal. Acute Cardiovascular Care, 7:158–65, 2018. https://doi.org/10.1177/2048872616661692.
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    • Melloni, Chiara, Allison Dunning, Christopher B. Granger, Laine Thomas, Michel G. Khouri, David A. Garcia, Elaine M. Hylek, et al. “Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial..” In The American Journal of Medicine, 130:1440-1448.e1, 2017. https://doi.org/10.1016/j.amjmed.2017.06.026.
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    • Lehman, E Philip, Patricia Cowper, Tiffany Randolph, Andrzej Kosinski, Ranato D. Lopes, and Pamela Douglas. “UNIVERSAL USE OF CONTRAST TO DETECT LEFT VENTRICULAR THROMBUS IN PATIENTS WITH REDUCED EJECTION FRACTION IS NOT ASSOCIATED WITH IMPROVED CLINICAL OR COST-EFFECTIVENESS OUTCOMES.” In Journal of the American College of Cardiology, 69:1639–1639. ELSEVIER SCIENCE INC, 2017.
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    • Hijazi, Ziad, Abhinav Sharma, Ulrika Andersson, John H. Alexander, Sana M. Al-Khatib, Michael Hanna, Claes Held, et al. “Biomarkers Predict Cause of Death More Accurately Than Clinical Variables in Patients With Atrial Fibrillation on Oral Anticoagulation Results From the ARISTOTLE Trial.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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    • Rao, P., J. H. Alexander, D. Wojdyla, D. Atar, E. M. Hylek, M. Hanna, A. Parkhomenko, et al. “Patients with atrial fibrillation and history of falls are at high risk for bleeding but have less bleeding with apixaban than warfarin: results from the ARISTOTLE trial.” In European Heart Journal, 37:233–34. OXFORD UNIV PRESS, 2016.
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    • Harskamp, Ralf E., Niels Hoedemaker, L Kristin Newby, Pier Woudstra, Maik J. Grundeken, Marcel A. Beijk, Jan J. Piek, Jan G. Tijssen, Rajendra H. Mehta, and Robbert J. de Winter. “Procedural and clinical outcomes after use of the glycoprotein IIb/IIIa inhibitor abciximab for saphenous vein graft interventions..” In Cardiovascular Revascularization Medicine : Including Molecular Interventions, 17:19–23, 2016. https://doi.org/10.1016/j.carrev.2015.09.005.
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    • Zimerman, Andre, Amanda L. Stebbins, Renato D. Lopes, Patricia O. Guimaraes, Stefan K. James, John H. Alexander, Pierluigi Tricoci, et al. “Adverse Event Reporting in > 48,000 Participants in Four Acute Coronary Syndrome Trials.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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    • Alexander, J., U. Andersson, R. D. Lopes, Z. Hijazi, S. H. Hohnloser, J. Ezekowitz, S. Halvorsen, M. Hanna, C. B. Granger, and L. Wallentin. “Stroke and bleeding outcomes with apixaban versus warfarin in patients with high creatinine, low body weight or high age receiving standard dose apixaban for stroke prevention in atrial fibrillation.” In European Heart Journal, 36:345–345. OXFORD UNIV PRESS, 2015.
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    • Avezum, Alvaro, Renato D. Lopes, Phillip J. Schulte, Fernando Lanas, Bernard J. Gersh, Michael Hanna, Prem Pais, et al. “Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial..” In Circulation, 132:624–32, 2015. https://doi.org/10.1161/circulationaha.114.014807.
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    • Bahit, M. C., R. D. Lopes, D. M. Wojdyla, C. Held, M. Hanna, D. Vinereanu, S. Goto, J. H. Alexander, L. Wallentin, and C. B. Granger. “Less non-major bleeding with apixaban versus warfarin among patients with atrial fibrillation: insights from the ARISTOTLE trial.” In European Heart Journal, 36:338–39. OXFORD UNIV PRESS, 2015.
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    • Hagstrom, E., D. Wojdyla, M. L. Neely, S. R. Stevens, R. A. Harrington, L. Wallentin, J. H. Alexander, S. G. Goodman, and R. D. Lopes. “Management and clinical consequences of major bleeding in high-risk patients following an acute coronary syndrome. Is aspirin the problem? Insights from the APPRAISE-2 trial.” In European Heart Journal, 36:861–62. OXFORD UNIV PRESS, 2015.
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    • Hijazi, Z., S. H. Hohnloser, U. Andersson, J. H. Alexander, C. B. Granger, M. Hanna, R. D. Lopes, A. Siegbahn, and L. Wallentin. “Efficacy and safety of apixaban compared with warfarin in relation to renal function over time in patients with atrial fibrillation: Insights from the ARISTOTLE trial.” In European Heart Journal, 36:339–339. OXFORD UNIV PRESS, 2015.
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    • Rordorf, R., G. M. De Ferrari, D. Wojdyla, R. De Caterina, L. Thomas, C. B. Granger, S. Leonardi, J. H. Alexander, L. Wallentin, and R. D. Lopes. “Digoxin use is associated with higher mortality among patients with atrial fibrillation with and without heart failure: insights from the ARISTOTLE trial.” In European Heart Journal, 36:1068–1068. OXFORD UNIV PRESS, 2015.
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    • Durheim, M. T., D. D. Cyr, S. M. Al-Khatib, L. E. Thomas, R. D. Lopes, B. J. Gersh, S. M. Palmer, and C. B. Granger. “Chronic Obstructive Pulmonary Disease Is Associated With Increased Risk Of Mortality Among Patients With Atrial Fibrillation: Insights From The Aristotle Trial.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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    • Williams, Judson B., Eric D. Peterson, Daniel Wojdyla, Ralf Harskamp, Kevin W. Southerland, T Bruce Ferguson, Peter K. Smith, Carmelo A. Milano, and Renato D. Lopes. “Central venous pressure after coronary artery bypass surgery: does it predict postoperative mortality or renal failure?.” In Journal of Critical Care, 29:1006–10, 2014. https://doi.org/10.1016/j.jcrc.2014.05.027.
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    • Cowper, Patricia A., Shubin Sheng, Kevin J. Anstrom, Judith A. Stafford, Renato D. Lopes, Linda Davidson-Ray, Lars Wallentin, et al. “The Cost-Effectiveness of Apixaban versus Warfarin in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Study Group.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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    • Hijazi, Ziad, Agneta Siegbahn, Ulrike Andersson, Bertil Lindahl, Christopher B. Granger, John H. Alexander, Dan Atar, et al. “Does Repeat Measurement of High Sensitivity Troponin I Improve Prediction of Cardiovascular Events in Atrial Fibrillation?.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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    • Wallentin, Lars, Ziad Hijazi, Ulrike Andersson, Bertil Lindahl, Christopher B. Granger, John H. Alexander, Dan Atar, et al. “Single Measurement of GDF-15 Provides Reliable Prognostication of Stroke and Major Bleeding in Atrial Fibrillation.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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    • Asberg, S., Z. Hijazi, A. Siegbahn, U. Andersson, C. B. Granger, M. Hanna, J. D. Horowitz, R. D. Lopes, B. Lindahl, and L. Wallentin. “Galectin-3 is associated with worse clinical outcome in patients with atrial fibrillation: A substudy from the ARISTOTLE trial.” In European Heart Journal, 35:426–426. OXFORD UNIV PRESS, 2014.
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    • Aulin, J., Z. Hijazi, U. Andersson, B. J. Gersh, M. Hanna, J. D. Horowitz, E. M. Hylek, R. D. Lopes, A. Siegbahn, and L. Wallentin. “Interleukin-6 and C-reactive protein and risk for cardiovascular events and death in anticoagulated patients with atrial fibrillation.” In European Heart Journal, 35:1115–16. OXFORD UNIV PRESS, 2014.
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    • Christersson, C., L. Wallentin, U. Andersson, E. M. Hylek, S. Husted, R. De Caterina, M. Hanna, R. D. Lopes, C. B. Granger, and A. Siegbahn. “The efficacy of apixaban compared to warfarin in patients with atrial fibrillation with high coagulation activity despite anticoagulant treatment.” In European Heart Journal, 35:866–67. OXFORD UNIV PRESS, 2014.
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    • Harskamp, R. E., J. H. Alexander, R. Hager, B. Englum, P. J. Schulte, E. D. Peterson, C. M. Gibson, R. M. Califf, T. B. Ferguson, and R. D. Lopes. “Predictors of and clinical outcomes after internal mammary artery graft failure: insights from the PREVENT-IV trial.” In European Heart Journal, 35:1052–53. OXFORD UNIV PRESS, 2014.
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    • Hijazi, Z., J. Lindback, A. Siegbahn, J. H. Alexander, C. Held, M. Hanna, R. D. Lopes, J. Oldgren, C. B. Granger, and L. Wallentin. “A new biomarker based risk score for predicting major bleeding in atrial fibrillation - the ABC (age, biomarkers, current disease) risk score.” In European Heart Journal, 35:357–357. OXFORD UNIV PRESS, 2014.
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    • Harskamp, R. E., J. D. Puskas, J. G. Tijssen, P. F. Walker, H. A. Liberman, R. D. Lopes, T. A. Vassiliades, E. D. Peterson, and M. E. Halkos. “Comparison of hybrid coronary revascularization versus coronary artery bypass grafting in patients ≥65 years with multivessel coronary artery disease.” In American Journal of Cardiology, 114:224–29, 2014. https://doi.org/10.1016/j.amjcard.2014.04.028.
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    • Hijazi, Ziad, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, John H. Alexander, Dan Atar, Bernard J. Gersh, et al. “High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin..” In Journal of the American College of Cardiology, 63:52–61, 2014. https://doi.org/10.1016/j.jacc.2013.07.093.
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    • Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, Colleen M. Brophy, Michael I. Mack, Eric D. Peterson, Judson B. Williams, et al. “Preservation Solutions, Patency, and Outcomes After Coronary Bypass Surgery.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Hijazi, Ziad, Agneta Siegbahn, Ulrika Andersson, Christopher B. Granger, John H. Alexander, Dan Atar, Bernard I. Gersh, et al. “Combining High Sensitivity Troponin I and T Measurements Improves Prediction of Long-Term Clinical Outcomes in Patients With Atrial Fibrillation - An Aristotle Substudy.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Lopes, Renato D., Benjamin Neely, E. M. Ohman, Diego Ardissino, Christian Hamm, Shaun G. Goodman, Deepak L. Rhatt, et al. “Timing, Profile, and Predictors of Spontaneous Myocardial Infarction Following a Non-ST-Segment Elevation Acute Coronary Syndrome Event: Insights From the TRILOGY-ACS Trial.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Lopes, Renato D., DaJuanicia N. Holmes, Laine Thomas, Jack Ansell, Gregg C. Fonarow, Bernard J. Gersh, Alan S. Go, et al. “Triple Versus Dual Antithrombotic Therapy in Patients With Atrial Fibrillation and History of Coronary Artery Disease: Insights From the ORBIT-AF Registry.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Pereira, Sabrina B., Renato D. Lopes, Maria Julia Carrion, Eliana V. Santucci, Rafael M. Soares, Matheus O. Abreu, Ligia N. Laranjeira, et al. “Early Termination of Cardiovascular Clinical Trials Registered in ClinicalTrials.gov: Where Do We Stand?.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Vinereanu, Dragos, Susanna R. Stevens, John H. Alexander, Sana M. Al-Khatib, Alvaro Avezum, Cecilia Bahit, Christopher B. Granger, et al. “Efficacy and Safety of Apixaban in Patients With Atrial Fibrillation According to Sex: Results From the ARISTOTLE Trial.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Harskamp, R. E., J. M. Brennan, J. G. Gaca, M. E. Halkos, E. D. Peterson, S. V. Rao, J. B. Williams, R. J. De Winter, J. H. Alexander, and R. D. Lopes. “A systematic review of outcomes related to hybrid coronary revascularization in patients with multi-vessel coronary artery disease in the drug-eluting stent era.” In European Heart Journal, 34:834–834. OXFORD UNIV PRESS, 2013.
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    • Held, C., E. B. Hylek, J. H. Alexander, M. Hanna, R. D. Lopes, D. Wojdyla, C. B. Granger, and L. Wallentin. “Risk of events in the 30 days following a major bleed with Apixaban or Warfarin - experiences from the ARISTOTLE trial.” In European Heart Journal, 34:99–99. OXFORD UNIV PRESS, 2013.
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    • Hess, C. N., J. H. Alexander, M. L. Neely, S. James, D. Liaw, J. Amerena, A. Parkhomenko, R. A. Harrington, and R. D. Lopes. “International variation in management and outcomes in high-risk patients following acute coronary syndromes: results from the APPRAISE-2 trial.” In European Heart Journal, 34:885–885. OXFORD UNIV PRESS, 2013.
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    • Lopes, R. D., D. A. Garcia, D. Wojdyla, P. Dorian, J. H. Alexander, L. Wallentin, F. Lanas, M. Hanna, C. Held, and C. B. Granger. “Use of apixaban and warfarin in patients undergoing invasive procedures: insights from ARISTOTLE.” In European Heart Journal, 34:98–99. OXFORD UNIV PRESS, 2013.
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    • Lopes, Renato D., Alvaro Albrecht, Judson Williams, Shuang Li, T. Ferguson, Renato Kalil, Adrian Hernandez, and Eric Peterson. “HOSPITAL VARIATION IN PERIOPERATIVE INSULIN USE AND GLUCOSE CONTROL IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY.” In Journal of the American College of Cardiology, 61:E1567–E1567. Elsevier BV, 2013. https://doi.org/10.1016/s0735-1097(13)61567-3.
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    • Lopes, Renato D., Alvaro Albrecht, Judson Williams, Shuang Li, T. Ferguson, Renato Kalil, Adrian Hernandez, and Eric Peterson. “POSTOPERATIVE GLUCOSE CONTROL FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY: PREDICTORS AND CLINICAL OUTCOMES.” In Journal of the American College of Cardiology, 61:E1601–E1601. Elsevier BV, 2013. https://doi.org/10.1016/s0735-1097(13)61601-0.
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    • Lopes, R. D. “Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation,” 2013.
    • Fonteles Ritt, Luiz Eduardo, Gilson Soares Feitosa, Antonio Carlos Carvalho, Joel Alves Pinho Filho, Cristiano Bastos Macedo, Fabio Vilas Boas, Marcus Vinicius Andrade, et al. “Heart Failure Surviving Score is an Independent Predictor of Higher Long-Term Mortality in Patients with Heart Failure Due to Chagas Disease.” In Cardiovascular Therapeutics, 30:33–33. WILEY-BLACKWELL, 2012.
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    • Fonteles Ritt, Luiz Eduardo, Gilson Soares Feitosa, Antonio Carlos Carvalho, Joel Alves Pinho Filho, Cristiano Bastos Macedo, Fabio Vilas Boas, Marcus Vinicius Andrade, et al. “Improvement in the Six-Minute Walking Test is an Independent Predictor of Better Quality of Life in Heart Failure Due to Chagas Disease.” In Cardiovascular Therapeutics, 30:37–37. WILEY-BLACKWELL, 2012.
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    • Cornel, J., S. James, R. D. Lopes, P. Mohan, M. Neely, J. Amerena, Y. Huo, J. H. Alexander, R. A. Harrington, and L. Wallentin. “Apixaban after acute coronary syndrome in patients with heart failure: insights from the APPRAISE-2 trial.” In European Heart Journal, 33:335–36. OXFORD UNIV PRESS, 2012.
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    • McMurray, J. J. V., B. Lewis, J. Ezekowitz, B. Gersh, R. D. Lopes, D. Wojdyla, P. Mohan, L. Wallentin, J. H. Alexander, and C. B. Granger. “Risk of stroke, systemic embolism or death according to heart failure and left ventricular function status in patients with atrial fibrillation: results of the ARISTOTLE trial.” In European Heart Journal, 33:519–519. OXFORD UNIV PRESS, 2012.
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    • McMurray, J. J. V., S. J. Connolly, R. Hart, G. Flaker, R. D. Lopes, J. Wang, M. Hanna, J. H. Alexander, C. B. Granger, and L. Wallentin. “Effect of apixaban on all-cause mortality in atrial fibrillation: an imputed placebo analysis.” In European Heart Journal, 33:52–52. OXFORD UNIV PRESS, 2012.
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    • Siegbahn, A., C. Christersson, M. Schollin, J. H. Alexander, J. Horowitz, E. M. Hylek, R. D. Lopes, P. Mohan, C. B. Granger, and L. Wallentin. “Increased levels of D-dimer identify patients with atrial fibrillation at high risk for bleeding an ARISTOTLE substudy.” In European Heart Journal, 33:51–51. OXFORD UNIV PRESS, 2012.
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    • Lopes, Renato D., Sana Al-Khatib, Lars Wallentin, Hongqiu Yang, Jack Ansell, J Donald Easton, Cetin Erol, et al. “EFFICACY AND SAFETY OF APIXABAN COMPARED WITH WARFARIN ACCORDING TO CHADS2 AND HASBLED RISK SCORES FOR STROKE PREVENTION IN ATRIAL FIBRILLATION.” In Journal of the American College of Cardiology, 59:E574–E574. Elsevier BV, 2012. https://doi.org/10.1016/s0735-1097(12)60575-0.
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    • Fosbøl, Emil L., Tracy Y. Wang, Jonathan Piccini, Renato D. Lopes, Bimal Shah, Karen P. Alexander, Shuang Li, Matthew T. Roe, and Eric D. Peterson. “LONG-TERM SAFETY OF ANTITHROMBOTIC THERAPY IN NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION PATIENTS WITH ATRIAL FIBRILLATION.” In Journal of the American College of Cardiology, 57:E948–E948. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60948-0.
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    • Truffa, Adriano A., Renato D. Lopes, Kyle R. White, Rajendra H. Mehta, Manesh R. Patel, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “SERIOUS INFECTIONS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PCI ARE RARE, BUT ASSOCIATED WITH HIGHER MORTALITY.” In Journal of the American College of Cardiology, 57:E980–E980. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60980-7.
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    • Kuijt, WJ, Roe, MT, Green, CL, Pieper, KS, Stevens, SR, Lopes, RD, Christenson, RH, Tijssen, JG, Stone, GW, Lincoff, AM, De Winter, RJ, and Krucoff, MW. "PREDICTION OF DEATH AND CONGESTIVE HEART FAILURE USING MULTIPLE CONCOMITANT ANGIOGRAPHIC BIOCHEMICAL AND ELECTROCARDIOGRAPHIC BIOMARKERS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION." : Elsevier BV, April 2011.  Full Text
    • Mehta, R., E. Honeycutt, R. D. Lopes, L. K. Shaw, and M. H. Sketch. “Acute renal failure after coronary artery bypass surgery: impact of recovery of renal function on long-term mortality.” In European Heart Journal, 31:612–612. OXFORD UNIV PRESS, 2010.
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    • Mehta, R., T. B. Ferguson, R. D. Lopes, G. E. Hafley, M. J. Mack, N. T. Kouchoukos, C. M. Gibson, R. A. Harrington, R. M. Califf, and J. H. Alexander. “Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the PREVENT-IV trial.” In European Heart Journal, 31:881–881. OXFORD UNIV PRESS, 2010.
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    • Chan, Mark, Jie L. Sun, Tracy Y. Wang, Renato D. Lopes, Marc E. Jolicoeur, Karen S. Pieper, Sunil V. Rao, et al. “Discharge Without Antiplatelet Therapy After Inhospital Bleeding is an Independent Predictor of 6-Month Mortality Among Patients With Acute Coronary Syndrome: A Pooled Analysis From PURSUIT, PARAGON-A, PARAGON-B and SYNERGY.” In Circulation, 120:S1144–S1144. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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    • Mehta, Rajendra H., Renato D. Lopes, Amanda Stebbins, Sunil V. Rao, Karen S. Pieper, Robert M. Califf, John H. Alexander, and Christopher B. Granger. “Differences in Bleeding Rates Accounts for All of the Excess Mortality in African Americans Compared With Caucasians With ST-Elevation Myocardial Infarction treated With Fibrinolysis.” In Circulation, 120:S522–23. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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    • Lopes, Renato D., Harvey D. White, Judith Hochman, John R. Horton, Frans Van de Werf, Diego Ardissino, Torsten T. Nielsen, et al. “New onset atrial fibrillation following myocardial infarction is a strong independent predictor of mortality in patients treated with primary percutaneous coronary intervention.” In Journal of the American College of Cardiology, 51:A11–12. ELSEVIER SCIENCE INC, 2008.
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