Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.H.S., Duke University School of Medicine 2009
  • Ph.D., Paulista Medical School, University of Sao Paulo (Brazil) 2006
  • M.D., University of Santo Amaro (Brazil) 2001
• 

  Duke Appointment History

  • Associate Professor of Medicine, Medicine, Cardiology, Medicine 2013 - 2016
  • Adjunct Assistant Professor in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2009 - 2013
• Recognition
• 

  In the News

  • AUG 28, 2017

    Duke Health News

    Education and Monitoring Improves the Use of Stroke-Prevention Therapies
• Expertise
• 

  Global Scholarship

  • Expertise

    • Brazil (Country) 

  • Research

    • Brazil (Country) 

  • Teaching

    • Brazil (Country) 
• Research
• 

  Selected Grants

  • Trial to Assess Chelation Therapy 2 (TACT2) DCC awarded by National Institutes of Health 2015 - 2021
  • Sanofi SOTA Outcomes EFC15156 awarded by Sanofi US 2018 - 2021
  • ASCEND_protocol 205270 awarded by GlaxoSmithKline 2017 - 2020
  • Trial to Assess Chelation Therapy 2 (TACT2) DCC awarded by National Institutes of Health 2015 - 2020
  • GSK-CKD program_CEC awarded by GlaxoSmithKline 2017 - 2020
  • DCRI-Stanford CEC Summit awarded by Baim Institute for Clinical Research 2018 - 2020
  • DCRI-Stanford CEC Summit awarded by WIRB-Copernicus Group 2018 - 2020
  • DCRI-Stanford Symposium awarded by AG Mednet 2018 - 2020
  • DCRI-Stanford Symposium awarded by Language Scientific, Inc. 2018 - 2020
  • Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
  • Lilly GPGB Diabetes Study awarded by Eli Lilly and Company 2017 - 2019
  • AMG785-2015242 awarded by Amgen, Inc. 2017 - 2018
  • HeartRescue Brazil (RAPIDO) awarded by Research Triangle Institute International 2016 - 2018
  • CEC Adjudications for Lilly GIP_GLP1 awarded by Eli Lilly and Company 2017 - 2018
  • a retrospective re-review of all negatively adjudicated events (NAE) across three (3) protocols/studies awarded by Amgen, Inc. 2018
  • Educational Preceptorship Agreement awarded by Pfizer, Inc. 2017 - 2018
  • Bacteremia Modification 14 awarded by National Institutes of Health 2009 - 2017
  • Mod 11 for Option 3 - Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2017
  • Modification No 13 Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2017
  • GBGJ Dulaglutide_CEC awarded by Eli Lilly and Company 2016 - 2017
  • Modification No. 8 - Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2016
• Publications & Artistic Works
• 

  Selected Publications

  • Books

    • Understanding Clinical Trials (Portuguese). Edited by RD Lopes and RA Harrington. New York: McGraw-Hill, 2014.
    • Guimarães, HP, Zazula, AD, Lopes, RD, and Berwanger, O. Practical Guidance for Patients with Acute Coronary Syndrome. San Paulo: Athenu, 2014.
    • Understanding Clinical Trials. Edited by RD Lopes and RA Harrington. New York: McGraw-Hill, 2013.
    • Calff, RM, and Roe, M. Acute Coronary Syndromes: ACE Essentials. Physicians Press, 2010.
    • Calff, RM, and Roe, M. Acute Coronary Syndromes: ACE Essentials. Physicians Press, 2010.
    • Lopes, RD. Acid-base and Hydro-electrolytic Balance. Editora Atheneu, 2009. (Monograph)
    • Lopes, AC, Lopes, RD, and Freire, F. Ambulatory Internal Medicine. Ed Sao Paulo: Editora Manolle, 2007.
    • Guimaraes, HP, Lopes, RD, and Lopes, AC. Cardio-Respiratory Arrest. Ed Sao Paulo: Editora Atheneu, 2005.

  • Book Sections

    • De Carvalho, ACC, Lopes, RD, and de Paola, AAV. "Atrial fibrillation and stroke prevention." In Prevention of Cardiovascular Diseases: From Current Evidence to Clinical Practice, 261-276. August 28, 2015.  Full Text
    • Berwanger, O, Biasi, A, and Lopes, RD. "Designing Clinical Trials in Cardiology." In Intensive Care in Cardiology, edited by E Knobel. Atheneu, 2015. (Chapter)
    • Brito, FS, and Lopes, RD. "Antithrombotic Therapy in Cardiology." In Intensive Care in Cardiology, edited by E Knobel. Atheneu, 2015. (Chapter)
    • Lopes, RD. "Antithrombotic Therapy in Atrial Fibrillation." In Intensive Care in Cardiology, edited by E Knobel. Atheneu, 2015. (Chapter)
    • Pesaro, AEP, and Lopes, RD. "Non-ST Elevation Acute Coronary Syndrome." In Intensive Care in Cardiology, edited by E Knobel. Atheneu, 2015. (Chapter)
    • Barros e Silva, PGM, and Lopes, RD. "Cardiac Cycle and Importance of Physical Examination." In Cardiology, edited by M Moreira, ST Montenegro, and AA de Paola. Manole: Brazilian Society of Cardiology, 2014. (Chapter)
    • Brito, FS, Lopes, RD, and Roe, MT. "Atherothrombosis." In Clinical Practice, edited by DL Bhatt. Oxford American Cardiovascular Library, 2013. (Chapter)
    • Reist, CJ, Rorick, TL, Berdan, LG, and Lopes, RD. "The Role of Academic Research Organizations in Clinical Research." In Understanding Clinical Trials, edited by RD Lopes and RA Harrington. New York: McGraw-Hill, 2013. (Chapter)
    • Lopes, RD, Chan, M, and Newby, LK. "Novel Markers in Patients with Suspected ACS." In Biomarkers in Heart Disease, edited by JA De Lemos. American Heart Association, 2008. (Chapter)
    • Lopes, AC, and Lopes, RD. "Arterial High Blood Pressure." In Emergency Medicine Manual, edited by AC Lopes, M ElenaGuariento, and L Ward. Editora Atheneu, 2006. (Chapter)
    • Lopes, RD, and Guimaraes, HP. "Acid-base and Hydro-electrolytic Balance." In Clinical Toxicology Fundamentals, edited by S Graff and AC Lopes. Editora Atheneu, 2006. (Chapter)
    • Almeida, CES, Lopes, RD, and Guimaraes, HP. "Introduction." In Acid-base and Hydro-electrolytic Balance, 3-11. Editora Atheneu, 2005. (Introduction)
    • Costa, MPF, Guimaraes, HP, and Lopes, RD. "Defibrillation and Electric." In Cardio Respiratory Stroke, 65-73. Editora Atheneu, 2005. (Chapter)
    • Feitosa Filho, GS, and Lopes, RD. "Therapeutic Hypothermia in Brain-Cardio Pulmonary Resuscitation." In Cardio Respiratory Stroke, 105-112. Editora Atheneu, 2005. (Chapter)
    • Fonsecca, MAJ, Lopes, RD, and Marques, FRB. "Crucial Algorithms to the Assistance to Cardio Respiratory Stroke." In Cardio Respiratory Stroke, 161-164. Editora Atheneu, 2005. (Chapter)
    • Gomes, EP, Siqueira, VN, and Lopes, RD. "Asystole." In Cardio Respiratory Stroke, 43-48. Editora Atheneu, 2005. (Chapter)
    • Guimaraes, HP, Filgueiras, N, and Lopes, RD. "Cardio Pulmonary and Brain Resuscitation." In Introduction to Intensive Medicine, edited by HP Guimaraes and AMDA Ferreira, 9-34. Sao Paulo, Brazil, 2005. (Chapter)
    • Guimaraes, HP, Lopes, RD, Falcão, LFR, and Segovia, LEJ. "Definition, Levels of Evidence and Diagnosis." In Cardio Respiratory Stroke, 1-5. Editora Atheneu, 2005. (Chapter)
    • Guimaraes, HP, Lopes, RD, and Barcelos, GK. "Internal and Transvein Pacemaker." In Cardio Respiratory Stroke, 91-97. Editora Atheneu, 2005. (Chapter)
    • Guimaraes, HP, Lopes, RD, and Costa, MP. "Basic Life Support (SBV)." In Cardio Respiratory Stroke, 7-35. Editora Atheneu, 2005. (Chapter)
    • Guimaraes, HP, and Lopes, RD. "Cardio Pulmonary Evaluation previous to exercises." In The Exercise as Therapy in Practical Medicine, edited by M Vaisberg, FBPC Rosa, and MT de Mello, 27-35. Sao Paulo, Brazil, 2005. (Chapter)
    • Lopes, RD, Guimaraes, HP, and Guimaraes, HP. "Ventricular Fibrillation (FV) and Ventricular Palpitation (TV) without Pulse." In Cardio Respiratory Stroke, 37-42. Editora Atheneu, 2005. (Chapter)
    • Lopes, RD, Rego, VLD, and Silva, MJB. "Clinical Cases." In Acid-base and Hydro-electrolytic Balance, 69-78. Editora Atheneu, 2005. (Chapter)
    • Lopes, RD, Silva, MJB, and Rego, VLD. "Primary Disturbances." In Acid-base and Hydro-electrolytic Balance, 13-54. Editora Atheneu, 2005. (Chapter)
    • Lopes, RD. "Conclusion." In Acid-base and Hydro-electrolytic Balance, 79-79. Editora Atheneu, 2005.
    • Rego, VLD, and Lopes, RD. "Secondary Disturbances (compensations) and Mixed." In Acid-base and Hydro-electrolytic Balance, 55-59. Editora Atheneu, 2005. (Chapter)
    • Silva, MJB, Lopes, RD, and Guimaraes, HP. "Systematic Approach of the Acid – base disturbances and Arterial Gas." In Acid-base and Hydro-electrolytic Balance, 61-67. Editora Atheneu, 2005. (Chapter)
    • Siqueira, VN, Mossini, JS, Guimaraes, HP, and Lopes, RD. "Drug Doses and Administration Modes." In Cardio Respiratory Stroke, 165-173. Editora Atheneu, 2005. (Chapter)
    • Lopes, AC, Liberatori Filho, AW, and Lopes, RD. "Non- Toxic High Blood Pressure Treatment during pregnancy." 171-175. Sao Paulo, Brazil: Medsi Editora Medica Cientifica Ltda, 2003. (Chapter)
    • Lopes, AC, Lopes, RD, and Liberatori Filho, AW. "Definition of Critical Pneumonia Acquired and Therapeutic Orientation for the Community." In Medical Practice Topics, 235-236. São Paulo, Brazil: Medsi Editora Médica e Cientifica Ltda, 2003. (Chapter)

  • Conference Papers

    • Leonardi, S, Lopes, RD, Steg, PG, Abnousi, F, Menozzi, A, Prats, J, Mangum, S, Wilson, M, Todd, M, Stone, GW, Gibson, CM, Hamm, CW, Price, MJ, White, HD, Harrington, RA, Bhatt, DL, and Mahaffey, KW. "Implications of different criteria for percutaneous coronary intervention-related myocardial infarction on study results of three large phase III clinical trials: The CHAMPION experience." March 2018.  Full Text
    • Melloni, C, Dunning, A, Granger, CB, Thomas, L, Khouri, MG, Garcia, DA, Hylek, EM, Hanna, M, Wallentin, L, Gersh, BJ, Douglas, PS, Alexander, JH, and Lopes, RD. "Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial." December 2017.  Full Text
    • Lehman, EP, Cowper, P, Randolph, T, Kosinski, A, Lopes, RD, and Douglas, P. "UNIVERSAL USE OF CONTRAST TO DETECT LEFT VENTRICULAR THROMBUS IN PATIENTS WITH REDUCED EJECTION FRACTION IS NOT ASSOCIATED WITH IMPROVED CLINICAL OR COST-EFFECTIVENESS OUTCOMES." March 21, 2017.  Link to Item
    • Hijazi, Z, Sharma, A, Andersson, U, Alexander, JH, Al-Khatib, SM, Hanna, M, Held, C, Hylek, EM, Lopes, RD, Siegbahn, A, Granger, CB, and Wallentin, L. "Biomarkers Predict Cause of Death More Accurately Than Clinical Variables in Patients With Atrial Fibrillation on Oral Anticoagulation Results From the ARISTOTLE Trial." November 11, 2016.  Link to Item
    • Rao, P, Alexander, JH, Wojdyla, D, Atar, D, Hylek, EM, Hanna, M, Parkhomenko, A, Vinereanu, D, Wallentin, L, Lopes, RD, Gersh, BJ, and Granger, CB. "Patients with atrial fibrillation and history of falls are at high risk for bleeding but have less bleeding with apixaban than warfarin: results from the ARISTOTLE trial." August 1, 2016.  Link to Item
    • Harskamp, RE, Hoedemaker, N, Newby, LK, Woudstra, P, Grundeken, MJ, Beijk, MA, Piek, JJ, Tijssen, JG, Mehta, RH, and de Winter, RJ. "Procedural and clinical outcomes after use of the glycoprotein IIb/IIIa inhibitor abciximab for saphenous vein graft interventions." January 2016.  Full Text
    • Zimerman, A, Stebbins, AL, Lopes, RD, Guimaraes, PO, James, SK, Alexander, JH, Tricoci, P, Roe, MT, Ohman, EM, Mahaffey, KW, Held, C, Tinga, B, Pieper, KS, and Alexander, KP. "Adverse Event Reporting in > 48,000 Participants in Four Acute Coronary Syndrome Trials." November 10, 2015.  Link to Item
    • Alexander, J, Andersson, U, Lopes, RD, Hijazi, Z, Hohnloser, SH, Ezekowitz, J, Halvorsen, S, Hanna, M, Granger, CB, and Wallentin, L. "Stroke and bleeding outcomes with apixaban versus warfarin in patients with high creatinine, low body weight or high age receiving standard dose apixaban for stroke prevention in atrial fibrillation." August 1, 2015.  Link to Item
    • Avezum, A, Lopes, RD, Schulte, PJ, Lanas, F, Gersh, BJ, Hanna, M, Pais, P, Erol, C, Diaz, R, Bahit, MC, Bartunek, J, De Caterina, R, Goto, S, Ruzyllo, W, Zhu, J, Granger, CB, and Alexander, JH. "Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial." August 2015.  Full Text
    • Bahit, MC, Lopes, RD, Wojdyla, DM, Held, C, Hanna, M, Vinereanu, D, Goto, S, Alexander, JH, Wallentin, L, and Granger, CB. "Less non-major bleeding with apixaban versus warfarin among patients with atrial fibrillation: insights from the ARISTOTLE trial." August 1, 2015.  Link to Item
    • Hagstrom, E, Wojdyla, D, Neely, ML, Stevens, SR, Harrington, RA, Wallentin, L, Alexander, JH, Goodman, SG, and Lopes, RD. "Management and clinical consequences of major bleeding in high-risk patients following an acute coronary syndrome. Is aspirin the problem? Insights from the APPRAISE-2 trial." August 1, 2015.  Link to Item
    • Hijazi, Z, Hohnloser, SH, Andersson, U, Alexander, JH, Granger, CB, Hanna, M, Lopes, RD, Siegbahn, A, and Wallentin, L. "Efficacy and safety of apixaban compared with warfarin in relation to renal function over time in patients with atrial fibrillation: Insights from the ARISTOTLE trial." August 1, 2015.  Link to Item
    • Rordorf, R, De Ferrari, GM, Wojdyla, D, De Caterina, R, Thomas, L, Granger, CB, Leonardi, S, Alexander, JH, Wallentin, L, Lopes, RD, and Trial, ARISTOTLE. "Digoxin use is associated with higher mortality among patients with atrial fibrillation with and without heart failure: insights from the ARISTOTLE trial." August 1, 2015.  Link to Item
    • Durheim, MT, Cyr, DD, Al-Khatib, SM, Thomas, LE, Lopes, RD, Gersh, BJ, Palmer, SM, and Granger, CB. "Chronic Obstructive Pulmonary Disease Is Associated With Increased Risk Of Mortality Among Patients With Atrial Fibrillation: Insights From The Aristotle Trial." 2015.  Link to Item
    • Williams, JB, Peterson, ED, Wojdyla, D, Harskamp, R, Southerland, KW, Ferguson, TB, Smith, PK, Milano, CA, and Lopes, RD. "Central venous pressure after coronary artery bypass surgery: does it predict postoperative mortality or renal failure?." December 2014.  Full Text
    • Cowper, PA, Sheng, S, Anstrom, KJ, Stafford, JA, Lopes, RD, Davidson-Ray, L, Wallentin, L, Phatak, HM, Ansell, J, Dorian, P, Husted, S, McMurray, JJ, Steg, PG, Alexander, JH, Granger, CB, and Mark, DB. "The Cost-Effectiveness of Apixaban versus Warfarin in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Study Group." November 25, 2014.  Link to Item
    • Hijazi, Z, Siegbahn, A, Andersson, U, Lindahl, B, Granger, CB, Alexander, JH, Atar, D, Gersh, BJ, Hanna, M, Harjola, V-P, Horowitz, JD, Husted, S, Hylek, EM, Lopes, RD, McMurray, JJ, and Wallentin, L. "Does Repeat Measurement of High Sensitivity Troponin I Improve Prediction of Cardiovascular Events in Atrial Fibrillation?." November 25, 2014.  Link to Item
    • Wallentin, L, Hijazi, Z, Andersson, U, Lindahl, B, Granger, CB, Alexander, JH, Atar, D, Gersh, BJ, Hanna, M, Harjola, V-P, Horowitz, JD, Husted, S, Hylek, EM, Lopes, RD, McMurray, JJ, and Siegbahn, A. "Single Measurement of GDF-15 Provides Reliable Prognostication of Stroke and Major Bleeding in Atrial Fibrillation." November 25, 2014.  Link to Item
    • Asberg, S, Hijazi, Z, Siegbahn, A, Andersson, U, Granger, CB, Hanna, M, Horowitz, JD, Lopes, RD, Lindahl, B, Wallentin, L, and Investigators, ARISTOTLE. "Galectin-3 is associated with worse clinical outcome in patients with atrial fibrillation: A substudy from the ARISTOTLE trial." September 1, 2014.  Link to Item
    • Aulin, J, Hijazi, Z, Andersson, U, Gersh, BJ, Hanna, M, Horowitz, JD, Hylek, EM, Lopes, RD, Siegbahn, A, and Wallentin, L. "Interleukin-6 and C-reactive protein and risk for cardiovascular events and death in anticoagulated patients with atrial fibrillation." September 1, 2014.  Link to Item
    • Christersson, C, Wallentin, L, Andersson, U, Hylek, EM, Husted, S, De Caterina, R, Hanna, M, Lopes, RD, Granger, CB, and Siegbahn, A. "The efficacy of apixaban compared to warfarin in patients with atrial fibrillation with high coagulation activity despite anticoagulant treatment." September 1, 2014.  Link to Item
    • Harskamp, RE, Alexander, JH, Hager, R, Englum, B, Schulte, PJ, Peterson, ED, Gibson, CM, Califf, RM, Ferguson, TB, and Lopes, RD. "Predictors of and clinical outcomes after internal mammary artery graft failure: insights from the PREVENT-IV trial." September 1, 2014.  Link to Item
    • Hijazi, Z, Lindback, J, Siegbahn, A, Alexander, JH, Held, C, Hanna, M, Lopes, RD, Oldgren, J, Granger, CB, Wallentin, L, and Investigators, ARISTOTLE. "A new biomarker based risk score for predicting major bleeding in atrial fibrillation - the ABC (age, biomarkers, current disease) risk score." September 1, 2014.  Link to Item
    • Harskamp, RE, Puskas, JD, Tijssen, JG, Walker, PF, Liberman, HA, Lopes, RD, Vassiliades, TA, Peterson, ED, and Halkos, ME. "Comparison of hybrid coronary revascularization versus coronary artery bypass grafting in patients ≥65 years with multivessel coronary artery disease." July 15, 2014.  Full Text
    • Hijazi, Z, Wallentin, L, Siegbahn, A, Andersson, U, Alexander, JH, Atar, D, Gersh, BJ, Hanna, M, Harjola, VP, Horowitz, JD, Husted, S, Hylek, EM, Lopes, RD, McMurray, JJV, Granger, CB, and ARISTOTLE Investigators, . "High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin." January 2014.  Full Text
    • Harskamp, RE, Alexander, JH, Schulte, PJ, Brophy, CM, Mack, MI, Peterson, ED, Williams, JB, Gibson, CM, Califf, RM, Kouchoukos, NT, Harrington, RA, Ferguson, TB, and Lopes, RD. "Preservation Solutions, Patency, and Outcomes After Coronary Bypass Surgery." Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association. Dallas, TX. November 16, 2013 - November 17, 2013. LIPPINCOTT WILLIAMS & WILKINS, November 26, 2013.  Link to Item
    • Hijazi, Z, Siegbahn, A, Andersson, U, Granger, CB, Alexander, JH, Atar, D, Gersh, BI, Hanna, M, Harjola, V-P, Horowitz, JD, Husted, S, Hylek, EM, Lopes, RD, McMurray, JJ, and Wallentin, L. "Combining High Sensitivity Troponin I and T Measurements Improves Prediction of Long-Term Clinical Outcomes in Patients With Atrial Fibrillation - An Aristotle Substudy." November 26, 2013.  Link to Item
    • Lopes, RD, Holmes, DN, Thomas, L, Ansell, J, Fonarow, GC, Gersh, BJ, Go, AS, Hylek, FM, Kowey, PR, Piccini, JP, Singer, DE, Chang, P, Peterson, ED, and Mahaffey, KW. "Triple Versus Dual Antithrombotic Therapy in Patients With Atrial Fibrillation and History of Coronary Artery Disease: Insights From the ORBIT-AF Registry." November 26, 2013.  Link to Item
    • Lopes, RD, Neely, B, Ohman, EM, Ardissino, D, Hamm, C, Goodman, SG, Rhatt, DL, Brown, EB, White, HD, Prabhakaran, D, Martinez, F, Nicolau, JC, Fox, KA, Armstrong, PW, and Roe, MT. "Timing, Profile, and Predictors of Spontaneous Myocardial Infarction Following a Non-ST-Segment Elevation Acute Coronary Syndrome Event: Insights From the TRILOGY-ACS Trial." November 26, 2013.  Link to Item
    • Pereira, SB, Lopes, RD, Carrion, MJ, Santucci, EV, Soares, RM, Abreu, MO, Laranjeira, LN, Ikeoka, DT, Zazula, A, Moreira, FR, Cavalcanti, AB, Mesquita, ET, Peterson, ED, Califf, RM, Berwanger, O, and Clinical, ME. "Early Termination of Cardiovascular Clinical Trials Registered in ClinicalTrials.gov: Where Do We Stand?." November 26, 2013.  Link to Item
    • Vinereanu, D, Stevens, SR, Alexander, JH, Al-Khatib, SM, Avezum, A, Bahit, C, Granger, CB, Lopes, RD, Halvorsen, S, Hanna, M, Husted, S, Hylek, EM, Margulescu, AD, Wallentin, L, and Atar, D. "Efficacy and Safety of Apixaban in Patients With Atrial Fibrillation According to Sex: Results From the ARISTOTLE Trial." November 26, 2013.  Link to Item
    • Harskamp, RE, Brennan, JM, Gaca, JG, Halkos, ME, Peterson, ED, Rao, SV, Williams, JB, De Winter, RJ, Alexander, JH, and Lopes, RD. "A systematic review of outcomes related to hybrid coronary revascularization in patients with multi-vessel coronary artery disease in the drug-eluting stent era." August 2013.  Link to Item
    • Held, C, Hylek, EB, Alexander, JH, Hanna, M, Lopes, RD, Wojdyla, D, Granger, CB, and Wallentin, L. "Risk of events in the 30 days following a major bleed with Apixaban or Warfarin - experiences from the ARISTOTLE trial." August 2013.  Link to Item
    • Hess, CN, Alexander, JH, Neely, ML, James, S, Liaw, D, Amerena, J, Parkhomenko, A, Harrington, RA, and Lopes, RD. "International variation in management and outcomes in high-risk patients following acute coronary syndromes: results from the APPRAISE-2 trial." August 2013.  Link to Item
    • Lopes, RD, Garcia, DA, Wojdyla, D, Dorian, P, Alexander, JH, Wallentin, L, Lanas, F, Hanna, M, Held, C, Granger, CB, and Investigators, ARISTOTLE. "Use of apixaban and warfarin in patients undergoing invasive procedures: insights from ARISTOTLE." August 2013.  Link to Item
    • Lopes, RD, Albrecht, A, Williams, J, Li, S, Ferguson, T, Kalil, R, Hernandez, A, and Peterson, E. "HOSPITAL VARIATION IN PERIOPERATIVE INSULIN USE AND GLUCOSE CONTROL IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY." March 2013.  Full Text
    • Lopes, RD, Albrecht, A, Williams, J, Li, S, Ferguson, T, Kalil, R, Hernandez, A, and Peterson, E. "POSTOPERATIVE GLUCOSE CONTROL FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY: PREDICTORS AND CLINICAL OUTCOMES." March 2013.  Full Text
    • Lopes, RD. "Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation." American College of Cardiology Scientific Session. 2013. 2013.
    • Fonteles Ritt, LE, Feitosa, GS, Carvalho, AC, Pinho Filho, JA, Macedo, CB, Boas, FV, Andrade, MV, Feitosa Filho, GS, Goncalves Almeida, AJ, Barojas, M, Carvalho, C, and Lopes, RD. "Improvement in the Six-Minute Walking Test is an Independent Predictor of Better Quality of Life in Heart Failure Due to Chagas Disease." November 2012.  Link to Item
    • Fonteles Ritt, LE, Feitosa, GS, Carvalho, AC, Pinho Filho, JA, Macedo, CB, Boas, FV, Andrade, MV, Feitosa Filho, GS, Goncalves Almeida, JA, Barojas, M, Carvalho, C, and Lopes, RD. "Heart Failure Surviving Score is an Independent Predictor of Higher Long-Term Mortality in Patients with Heart Failure Due to Chagas Disease." November 2012.  Link to Item
    • Cornel, J, James, S, Lopes, RD, Mohan, P, Neely, M, Amerena, J, Huo, Y, Alexander, JH, Harrington, RA, Wallentin, L, and Grp, AS. "Apixaban after acute coronary syndrome in patients with heart failure: insights from the APPRAISE-2 trial." August 2012.  Link to Item
    • McMurray, JJV, Connolly, SJ, Hart, R, Flaker, G, Lopes, RD, Wang, J, Hanna, M, Alexander, JH, Granger, CB, Wallentin, L, and Investigators, ARISTOTLE. "Effect of apixaban on all-cause mortality in atrial fibrillation: an imputed placebo analysis." August 2012.  Link to Item
    • McMurray, JJV, Lewis, B, Ezekowitz, J, Gersh, B, Lopes, RD, Wojdyla, D, Mohan, P, Wallentin, L, Alexander, JH, Granger, CB, and Investigators, ARISTOTLE. "Risk of stroke, systemic embolism or death according to heart failure and left ventricular function status in patients with atrial fibrillation: results of the ARISTOTLE trial." August 2012.  Link to Item
    • Siegbahn, A, Christersson, C, Schollin, M, Alexander, JH, Horowitz, J, Hylek, EM, Lopes, RD, Mohan, P, Granger, CB, and Wallentin, L. "Increased levels of D-dimer identify patients with atrial fibrillation at high risk for bleeding an ARISTOTLE substudy." August 2012.  Link to Item
    • Lopes, RD, Al-Khatib, S, Wallentin, L, Yang, H, Ansell, J, Easton, JD, Erol, C, Ezekowitz, J, Gersh, B, Hohnloser, S, Hylek, E, Bahit, C, Horowitz, J, De Caterina, R, Mohan, P, Vinereanu, D, Granger, C, and Alexander, J. "EFFICACY AND SAFETY OF APIXABAN COMPARED WITH WARFARIN ACCORDING TO CHADS2 AND HASBLED RISK SCORES FOR STROKE PREVENTION IN ATRIAL FIBRILLATION." March 27, 2012.  Full Text  Link to Item
    • Fosbol, EL, Wang, TY, Piccini, J, Lopes, RD, Shah, B, Alexander, KP, Li, S, Roe, MT, and Peterson, ED. "LONG-TERM SAFETY OF ANTITHROMBOTIC THERAPY IN NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION PATIENTS WITH ATRIAL FIBRILLATION." April 5, 2011.  Full Text  Link to Item
    • Kuijt, WJ, Roe, MT, Green, CL, Pieper, KS, Stevens, SR, Lopes, RD, Christenson, RH, Tijssen, JG, Stone, GW, Lincoff, AM, De Winter, RJ, and Krucoff, MW. "PREDICTION OF DEATH AND CONGESTIVE HEART FAILURE USING MULTIPLE CONCOMITANT ANGIOGRAPHIC, BIOCHEMICAL AND ELECTROCARDIOGRAPHIC BIOMARKERS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION." April 5, 2011.  Full Text  Link to Item
    • Truffa, AA, Lopes, RD, White, KR, Mehta, RH, Patel, MR, Pieper, KS, Armstrong, PW, and Granger, CB. "SERIOUS INFECTIONS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PCI ARE RARE, BUT ASSOCIATED WITH HIGHER MORTALITY." April 5, 2011.  Full Text  Link to Item
    • Mehta, R, Ferguson, TB, Lopes, RD, Hafley, GE, Mack, MJ, Kouchoukos, NT, Gibson, CM, Harrington, RA, Califf, RM, and Alexander, JH. "Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the PREVENT-IV trial." September 2010.  Link to Item
    • Mehta, R, Honeycutt, E, Lopes, RD, Shaw, LK, and Sketch, MH. "Acute renal failure after coronary artery bypass surgery: impact of recovery of renal function on long-term mortality." September 2010.  Link to Item
    • Chan, M, Sun, JL, Wang, TY, Lopes, RD, Jolicoeur, ME, Pieper, KS, Rao, SV, Newby, LK, Mahaffey, KW, Harrington, RA, and Peterson, ED. "Discharge Without Antiplatelet Therapy After Inhospital Bleeding is an Independent Predictor of 6-Month Mortality Among Patients With Acute Coronary Syndrome: A Pooled Analysis From PURSUIT, PARAGON-A, PARAGON-B and SYNERGY." November 3, 2009.  Link to Item
    • Mehta, RH, Lopes, RD, Stebbins, A, Rao, SV, Pieper, KS, Califf, RM, Alexander, JH, and Granger, CB. "Differences in Bleeding Rates Accounts for All of the Excess Mortality in African Americans Compared With Caucasians With ST-Elevation Myocardial Infarction treated With Fibrinolysis." November 3, 2009.  Link to Item
    • Lopes, RD, White, HD, Hochman, J, Horton, JR, Van de Werf, F, Ardissino, D, Nielsen, TT, Weaver, WD, Widimsky, P, Armstrong, PW, and Granger, CB. "New onset atrial fibrillation following myocardial infarction is a strong independent predictor of mortality in patients treated with primary percutaneous coronary intervention." March 11, 2008.  Link to Item

  • Journal Articles

    • Olivier, CB, Sundaram, V, Bhatt, DL, Leonardi, S, Lopes, RD, Ding, VY, Yang, L, Stone, GW, Steg, PG, Gibson, CM, Hamm, CW, Price, MJ, White, HD, Desai, M, Lynch, DR, Harrington, RA, Mahaffey, KW, and CHAMPION PLATFORM and CHAMPION PCI Investigators, . "Definitions of peri-procedural myocardial infarction and the association with one-year mortality: Insights from CHAMPION trials.(Accepted)" International Journal of Cardiology 270 (November 2018): 96-101.  Full Text
    • de Barros E Silva, PGM, Ribeiro, HB, Lopes, RD, Macedo, TA, Conejo, F, do Amaral Baruzzi, AC, Okada, MY, Garcia, JCT, Rodrigues, MJ, Furlan, V, and Ribeiro, EE. "Improvement in quality indicators using NCDR® registries: First international experience." International Journal of Cardiology 267 (September 2018): 13-15.  Full Text
    • Berwanger, O, Nicolau, JC, Carvalho, AC, Jiang, L, Goodman, S, Nicholls, SJ, Parkhomenko, A, Averkov, O, Tajer, C, Malaga, G, Kerr Saraiva, JF, Fonseca, F, Guimaraes, HP, de Barros e Silva, PGM, Damiani, LP, Paisani, DM, Lasagno, CMR, Candido, CT, Valeis, N, Moia, DDF, Piegas, LS, Granger, CB, White, H, and Lopes, RD. "Ticagrelor versus clopidogrel after fibrinolytic therapy in patients with ST-elevation myocardial infarction: Rationale and design of the ticagrelor in patients with ST elevation myocardial infarction treated with thrombolysis (TREAT) trial." American Heart Journal 202 (August 2018): 89-96.  Full Text
    • Capodanno, D, Mehran, R, Valgimigli, M, Baber, U, Windecker, S, Vranckx, P, Dangas, G, Rollini, F, Kimura, T, Collet, J-P, Gibson, CM, Steg, PG, Lopes, RD, Gwon, H-C, Storey, RF, Franchi, F, Bhatt, DL, Serruys, PW, and Angiolillo, DJ. "Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention." Nature Reviews. Cardiology 15, no. 8 (August 2018): 480-496. (Review)  Full Text
    • Vinereanu, D, Wang, A, Mulder, H, Lopes, RD, Jansky, P, Lewis, BS, Gersh, BJ, Avezum, A, Hanna, M, Held, C, Wallentin, L, Granger, CB, and Alexander, JH. "Outcomes in anticoagulated patients with atrial fibrillation and with mitral or aortic valve disease." Heart (British Cardiac Society) 104, no. 15 (August 2018): 1292-1299.  Full Text
    • van Diepen, S, Tran, DT, Ezekowitz, JA, Zygun, DA, Katz, JN, Lopes, RD, Newby, LK, McAlister, FA, and Kaul, P. "The high cost of critical care unit over-utilization for patients with NSTE ACS." American Heart Journal 202 (August 2018): 84-88.  Full Text
    • Lopes, RD, Rordorf, R, De Ferrari, GM, Leonardi, S, and Wallentin, L. "Reply: Digoxin Use in Atrial Fibrillation: Minimizing and Refining its Use When Still Needed." Journal of the American College of Cardiology 72, no. 1 (July 3, 2018): 125-126. (Letter)  Full Text
    • Berger, JS, Abramson, BL, Lopes, RD, Heizer, G, Rockhold, FW, Baumgartner, I, Fowkes, FGR, Held, P, Katona, BG, Norgren, L, Jones, WS, Millegård, M, Blomster, J, Reist, C, Hiatt, WR, Patel, MR, Mahaffey, KW, and EUCLID Trial Steering Committee and Investigators, . "Ticagrelor versus clopidogrel in patients with symptomatic peripheral artery disease and prior coronary artery disease: Insights from the EUCLID trial." Vascular Medicine (London, England) (July 2018): 1358863X18775594-null.  Full Text
    • Inohara, T, Pieper, K, Wojdyla, DM, Patel, MR, Jones, WS, Tricoci, P, Mahaffey, KW, James, SK, Alexander, JH, Lopes, RD, Wallentin, L, Ohman, EM, Roe, MT, and Vemulapalli, S. "Incidence, timing, and type of first and recurrent ischemic events in patients with and without peripheral artery disease after an acute coronary syndrome." American Heart Journal 201 (July 2018): 25-32.  Full Text
    • Lehman, EP, Cowper, PA, Randolph, TC, Kosinski, AS, Lopes, RD, and Douglas, PS. "Usefulness and Cost-Effectiveness of Universal Echocardiographic Contrast to Detect Left Ventricular Thrombus in Patients with Heart Failure and Reduced Ejection Fraction." The American Journal of Cardiology 122, no. 1 (July 2018): 121-128.  Full Text
    • Rymer, JA, Tempelhof, MW, Clare, RM, Pieper, KS, Granger, CB, Van de Werf, F, Moliterno, DJ, Harrington, RA, White, HD, Armstrong, PW, Lopes, RD, Mahaffey, KW, and Newby, LK. "Discharge timing and outcomes after uncomplicated non-ST-segment elevation acute myocardial infarction." American Heart Journal 201 (July 2018): 103-110.  Full Text
    • Lopes, RD, Vora, AN, Liaw, D, Granger, CB, Darius, H, Goodman, SG, Mehran, R, Windecker, S, and Alexander, JH. "An open-Label, 2 × 2 factorial, randomized controlled trial to evaluate the safety of apixaban vs. vitamin K antagonist and aspirin vs. placebo in patients with atrial fibrillation and acute coronary syndrome and/or percutaneous coronary intervention: Rationale and design of the AUGUSTUS trial." American Heart Journal 200 (June 2018): 17-23.  Full Text
    • Roever, L, Resende, ES, Diniz, ALD, Penha-Silva, N, O'Connell, JL, Gomes, PFS, Zanetti, HR, Roerver-Borges, AS, Veloso, FC, Souza, FRD, Duarte, PRA, Fidale, TM, Casella-Filho, A, Dourado, PMM, Chagas, ACP, Ali-Hasan-Al-Saegh, S, Reis, PEO, Pinto, RDMC, Oliveira, GBF, Avezum, Á, Neto, M, Durães, AR, Silva, RMFLD, Grande, AJ, Denardi, C, Lopes, RD, Nerlekar, N, Alizadeh, S, Hernandez, AV, Rosa, MID, Biondi-Zoccai, G, and Brazilian Network of Research in Meta-analysis (BRAMETIS), . "High-density lipoprotein-cholesterol functionality and metabolic syndrome: Protocol for review and meta-analysis." Medicine 97, no. 24 (June 2018): e11094-null. (Review)  Full Text
    • Sposato, LA, and Lopes, RD. "Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice." International Journal of Cardiology 261 (June 2018): 99-100.  Full Text
    • Lopes, RD, Steffel, J, Di Fusco, M, Keshishian, A, Luo, X, Li, X, Masseria, C, Hamilton, M, Friend, K, Gupta, K, Mardekian, J, Pan, X, Baser, O, and Jones, WS. "Effectiveness and Safety of Anticoagulants in Adults with Non-valvular Atrial Fibrillation and Concomitant Coronary/Peripheral Artery Disease." The American Journal of Medicine (May 26, 2018).  Full Text
    • Berwanger, O, Nicolau, JC, Carvalho, AC, Jiang, L, Goodman, SG, Nicholls, SJ, Parkhomenko, A, Averkov, O, Tajer, C, Malaga, G, Saraiva, JFK, Fonseca, FA, De Luca, FA, Guimaraes, HP, de Barros E Silva, PGM, Damiani, LP, Paisani, DM, Lasagno, CMR, Candido, CT, Valeis, N, Moia, DDF, Piegas, LS, Granger, CB, White, HD, Lopes, RD, and TREAT Study Group, . "Ticagrelor vs Clopidogrel After Fibrinolytic Therapy in Patients With ST-Elevation Myocardial Infarction: A Randomized Clinical Trial." Jama Cardiology 3, no. 5 (May 2018): 391-399.  Full Text
    • Lopes, RD, Guimarães, PO, Crowther, M, Hylek, E, Feitosa-Filho, GS, Ritt, LE, Filgueiras, N, and Garcia, DA. "Highlights from the Tenth International Symposium of Thrombosis and Anticoagulation (ISTA X), September 22 and 23, 2017, Salvador, Bahia, Brazil." Journal of Thrombosis and Thrombolysis 45, no. 4 (May 2018): 578-587. (Review)  Full Text
    • Wang, A, Wu, A, Wojdyla, D, Lopes, RD, Newby, LK, Newman, MF, Smith, PK, and Alexander, JH. "Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery." American Heart Journal 199 (May 2018): 150-155.  Full Text
    • Berwanger, O, Santucci, EV, de Barros E Silva, PGM, Jesuíno, IDA, Damiani, LP, Barbosa, LM, Santos, RHN, Laranjeira, LN, Egydio, FDM, Borges de Oliveira, JA, Dall Orto, FTC, Beraldo de Andrade, P, Bienert, IRDC, Bosso, CE, Mangione, JA, Polanczyk, CA, Sousa, AGDMR, Kalil, RAK, Santos, LDM, Sposito, AC, Rech, RL, Sousa, ACS, Baldissera, F, Nascimento, BR, Giraldez, RRCV, Cavalcanti, AB, Pereira, SB, Mattos, LA, Armaganijan, LV, Guimarães, HP, Sousa, JEMR, Alexander, JH, Granger, CB, Lopes, RD, and SECURE-PCI Investigators, . "Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome: The SECURE-PCI Randomized Clinical Trial." Jama 319, no. 13 (April 2018): 1331-1340.  Full Text
    • Berwanger, O, de Barros e Silva, PGM, Dall Orto, FTC, de Andrade, PB, de Castro Bienert, IR, Bosso, CE, Mangione, J, Polanczyk, CA, Sousa, A, Kalil, R, de Moura Santos, L, Sposito, AC, Rech, RL, Sousa, ACS, Baldissera, F, Nascimento, BR, de Andrade Jesuíno, I, Santucci, EV, Damiani, LP, Laranjeira, LN, Borges de Oliveira, JA, Giraldez, RR, Cavalcanti, AB, Pereira, SB, Mattos, LA, Armaganijan, LV, Guimarães, HP, Sousa, JE, Alexander, JH, Granger, CB, and Lopes, RD. "Rationale and design of the Statins Evaluation in Coronary procedUres and REvascularization: The SECURE-PCI Trial." American Heart Journal 198 (April 2018): 129-134.  Full Text
    • Goto, S, Merrill, P, Wallentin, L, Wojdyla, DM, Hanna, M, Avezum, A, Easton, JD, Harjola, V-P, Huber, K, Lewis, BS, Parkhomenko, A, Zhu, J, Granger, CB, Lopes, RD, and Alexander, JH. "Antithrombotic therapy use and clinical outcomes following thrombo-embolic events in patients with atrial fibrillation: insights from ARISTOTLE." European Heart Journal. Cardiovascular Pharmacotherapy 4, no. 2 (April 2018): 75-81.  Full Text
    • Roever, L, Resende, ES, Diniz, ALD, Penha-Silva, N, O'Connell, JL, Gomes, PFS, Zanetti, HR, Roerver-Borges, AS, Veloso, FC, Fidale, TM, Casella-Filho, A, Dourado, PMM, Chagas, ACP, Ali-Hasan-Al-Saegh, S, Reis, PEO, Pinto, RDM, Oliveira, GBF, Avezum, Á, Neto, M, Durães, A, Silva, RMFLD, Grande, AJ, Denardi, C, Lopes, RD, Nerlekar, N, Alizadeh, S, Hernandez, AV, Biondi-Zoccai, G, and Brazilian Network of Research in Meta-analysis (BRAMETIS), . "Metabolic syndrome and risk of stroke: Protocol for an update systematic review and meta-analysis." Medicine 97, no. 15 (April 2018): e9862-null. (Review)  Full Text
    • Roever, L, Resende, ES, Diniz, ALD, Penha-Silva, N, O'Connell, JL, Gomes, PFS, Zanetti, HR, Roerver-Borges, AS, Veloso, FC, Fidale, TM, Casella-Filho, A, Dourado, PMM, Chagas, ACP, Ali-Hasan-Al-Saegh, S, Reis, PEO, Pinto, RDM, Oliveira, GBF, Avezum, Á, Neto, M, Durães, A, Silva, RMFLD, Grande, AJ, Denardi, C, Lopes, RD, Nerlekar, N, Alizadeh, S, Hernandez, AV, Biondi-Zoccai, G, and Brazilian Network of Research in Meta-analysis (BRAMETIS), . "Statins in adult patients with HIV: Protocol for a systematic review and network meta-analysis." Medicine 97, no. 15 (April 2018): e0116-null. (Review)  Full Text
    • Roever, L, Resende, ES, Diniz, ALD, Penha-Silva, N, O'Connell, JL, Gomes, PFS, Zanetti, HR, Roerver-Borges, AS, Veloso, FC, Souza, FRD, Duarte, PRA, Fidale, TM, Casella-Filho, A, Dourado, PMM, Chagas, ACP, Ali-Hasan-Al-Saegh, S, Reis, PEO, Pinto, RDMC, Oliveira, GBF, Avezum, Á, Neto, M, Durães, A, Silva, RMFLD, Grande, AJ, Denardi, C, Lopes, RD, Nerlekar, N, Alizadeh, S, Hernandez, AV, Rosa, MID, Biondi-Zoccai, G, and Brazilian Network of Research in Meta-analysis (BRAMETIS), . "Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis." Medicine 97, no. 16 (April 2018): e0387-null.  Full Text
    • Roever, L, Resende, ES, Diniz, ALD, Penha-Silva, N, O'Connell, JL, Gomes, PFS, Zanetti, HR, Roerver-Borges, AS, Veloso, FC, de Souza, FR, Duarte, PRA, Fidale, TM, Casella-Filho, A, Dourado, PMM, Chagas, ACP, Ali-Hasan-Al-Saegh, S, Reis, PEO, Pinto, RDMC, Oliveira, GBF, Avezum, Á, Neto, M, Durães, A, Silva, RMFLD, Grande, AJ, Denardi, C, Lopes, RD, Nerlekar, N, Alizadeh, S, Hernandez, AV, Rosa, MID, Biondi-Zoccai, G, and Brazilian Network of Research in Meta-analysis (BRAMETIS), . "Epicardial adipose tissue and carotid artery disease: Protocol for systematic review and meta-analysis." Medicine 97, no. 17 (April 2018): e0273-null. (Review)  Full Text
    • Chiarito, M, Cao, D, Cannata, F, Godino, C, Lodigiani, C, Ferrante, G, Lopes, RD, Alexander, JH, Reimers, B, Condorelli, G, and Stefanini, GG. "Direct Oral Anticoagulants in Addition to Antiplatelet Therapy for Secondary Prevention After Acute Coronary Syndromes: A Systematic Review and Meta-analysis." Jama Cardiology 3, no. 3 (March 2018): 234-241.  Full Text
    • Kopin, D, Jones, WS, Sherwood, MW, Wojdyla, DM, Wallentin, L, Lewis, BS, Verheugt, FWA, Vinereanu, D, Bahit, MC, Halvorsen, S, Huber, K, Parkhomenko, A, Granger, CB, Lopes, RD, and Alexander, JH. "Percutaneous coronary intervention and antiplatelet therapy in patients with atrial fibrillation receiving apixaban or warfarin: Insights from the ARISTOTLE trial." American Heart Journal 197 (March 2018): 133-141.  Full Text
    • Lopes, RD, Rordorf, R, De Ferrari, GM, Leonardi, S, Thomas, L, Wojdyla, DM, Ridefelt, P, Lawrence, JH, De Caterina, R, Vinereanu, D, Hanna, M, Flaker, G, Al-Khatib, SM, Hohnloser, SH, Alexander, JH, Granger, CB, Wallentin, L, and ARISTOTLE Committees and Investigators, . "Digoxin and Mortality in Patients With Atrial Fibrillation." Journal of the American College of Cardiology 71, no. 10 (March 2018): 1063-1074.  Full Text
    • Paquet, M, Cerasuolo, JO, Thorburn, V, Fridman, S, Alsubaie, R, Lopes, RD, Cipriano, LE, Salamone, P, Melling, CWJ, Khan, AR, Sedeño, L, Fang, J, Drangova, M, Montero-Odasso, M, Mandzia, J, Khaw, AV, Racosta, JM, Paturel, J, Samoilov, L, Stirling, D, Balint, B, Jaremek, V, Koschinsky, ML, Boffa, MB, Summers, K, Ibañez, A, Mrkobrada, M, Saposnik, G, Kimpinski, K, Whitehead, SN, and Sposato, LA. "Pathophysiology and Risk of Atrial Fibrillation Detected after Ischemic Stroke (PARADISE): A Translational, Integrated, and Transdisciplinary Approach." Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association 27, no. 3 (March 2018): 606-619.  Full Text
    • Rao, MP, Vinereanu, D, Wojdyla, DM, Alexander, JH, Atar, D, Hylek, EM, Hanna, M, Wallentin, L, Lopes, RD, Gersh, BJ, Granger, CB, and Apixaban for Reduction in Stroke Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Investigators, . "Clinical Outcomes and History of Fall in Patients with Atrial Fibrillation Treated with Oral Anticoagulation: Insights From the ARISTOTLE Trial." The American Journal of Medicine 131, no. 3 (March 2018): 269-275.e2.  Full Text
    • Sherwood, MW, Lopes, RD, Sun, JL, Liaw, D, Harrington, RA, Wallentin, L, Laskowitz, DT, James, SK, Goodman, SG, Darius, H, Lewis, BS, Gibson, CM, Pieper, KS, and Alexander, JH. "Apixaban following acute coronary syndromes in patients with prior stroke: Insights from the APPRAISE-2 trial." American Heart Journal 197 (March 2018): 1-8.  Full Text
    • Sposato, LA, Fridman, S, Whitehead, SN, and Lopes, RD. "Linking stroke-induced heart injury and neurogenic atrial fibrillation: a hypothesis to be proven." Journal of Electrocardiology (February 20, 2018).  Full Text
    • Guimarães, PO, Leonardi, S, Huang, Z, Wallentin, L, de Werf, FV, Aylward, PE, Held, C, Harrington, RA, Moliterno, DJ, Armstrong, PW, White, HD, Alexander, KP, Lopes, RD, Mahaffey, KW, and Tricoci, P. "Clinical features and outcomes of patients with type 2 myocardial infarction: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial." American Heart Journal 196 (February 2018): 28-35.  Full Text
    • Hijazi, Z, Oldgren, J, Lindbäck, J, Alexander, JH, Connolly, SJ, Eikelboom, JW, Ezekowitz, MD, Held, C, Hylek, EM, Lopes, RD, Yusuf, S, Granger, CB, Siegbahn, A, Wallentin, L, and ARISTOTLE and RE-LY Investigators, . "A biomarker-based risk score to predict death in patients with atrial fibrillation: the ABC (age, biomarkers, clinical history) death risk score." European Heart Journal 39, no. 6 (February 2018): 477-485.  Full Text
    • Pol, T, Held, C, Westerbergh, J, Lindbäck, J, Alexander, JH, Alings, M, Erol, C, Goto, S, Halvorsen, S, Huber, K, Hanna, M, Lopes, RD, Ruzyllo, W, Granger, CB, and Hijazi, Z. "Dyslipidemia and Risk of Cardiovascular Events in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Therapy: Insights From the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) Trial." Journal of the American Heart Association 7, no. 3 (February 2018).  Full Text
    • Sposato, LA, and Lopes, RD. "Oral anticoagulation: a step toward solving the puzzle of dementia related to atrial fibrillation?." European Heart Journal 39, no. 6 (February 2018): 461-463.  Full Text
    • Vaduganathan, M, Harrington, R, Stone, G, Steg, G, Gibson, C, Hamm, C, Price, M, Lopes, R, Leonardi, S, Deliargyris, E, Prats, J, Mahaffey, K, White, H, and Bhatt, D. "Short- and long-term mortality following bleeding events in patients undergoing percutaneous coronary intervention: insights from four validated bleeding scales in the CHAMPION trials." Eurointervention 13, no. 15 (February 2018): e1841-e1849.  Full Text
    • Sharma, A, Green, JB, Dunning, A, Lokhnygina, Y, Al-Khatib, SM, Lopes, RD, Buse, JB, Lachin, JM, Van de Werf, F, Armstrong, PW, Kaufman, KD, Standl, E, Chan, JCN, Distiller, LA, Scott, R, Peterson, ED, Holman, RR, and TECOS Study Group, . "Causes of Death in a Contemporary Cohort of Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: Insights From the TECOS Trial." Diabetes Care 40, no. 12 (December 2017): 1763-1770.  Full Text
    • Vinereanu, D, Lopes, RD, Mulder, H, Gersh, BJ, Hanna, M, de Barros E Silva, PGM, Atar, D, Wallentin, L, Granger, CB, Alexander, JH, and ARISTOTLE Investigators, . "Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin." Stroke 48, no. 12 (December 2017): 3266-3273.  Full Text
    • Williams, JB, Peterson, ED, Albrecht, ÁS, Li, S, Hirji, SA, Ferguson, T, Smith, PK, and Lopes, RD. "Glycemic control in patients undergoing coronary artery bypass graft surgery: Clinical features, predictors, and outcomes." Journal of Critical Care 42 (December 2017): 328-333.  Full Text
    • Lopes, RD, Guimarães, PO, Hylek, E, Feitosa-Filho, GS, Ritt, L, Filgueiras, N, Darzé, E, Rocha, MS, Magalhães, LP, Sousa, ACS, Correia, LC, Oliveira, LH, and Garcia, DA. "Highlights from the Ninth International Symposium of Thrombosis and Anticoagulation (ISTA IX), October 15, 2016, Salvador, Bahia, Brazil." Journal of Thrombosis and Thrombolysis 44, no. 4 (November 2017): 544-555. (Review)  Full Text
    • Kittle, J, Lopes, RD, Huang, M, Marquess, ML, Wilson, MD, Ascher, J, Krishen, A, Hasselblad, V, Kolls, BJ, Roe, MT, McGuire, DK, Russell, SD, and Mahaffey, KW. "Cardiovascular adverse events in the drug-development program of bupropion for smoking cessation: A systematic retrospective adjudication effort." Clinical Cardiology 40, no. 10 (October 2017): 899-906.  Full Text
    • Koshizaka, M, Lopes, RD, Newby, LK, Clare, RM, Schulte, PJ, Tricoci, P, Mahaffey, KW, Ogawa, H, Moliterno, DJ, Giugliano, RP, Huber, K, James, S, Harrington, RA, and Alexander, JH. "Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites." The American Journal of Medicine 130, no. 10 (October 2017): 1170-1176.  Full Text
    • Ridker, PM, MacFadyen, JG, Thuren, T, Everett, BM, Libby, P, Glynn, RJ, Ridker, P, Lorenzatti, A, Krum, H, Varigos, J, Siostrzonek, P, Sinnaeve, P, Fonseca, F, Nicolau, J, Gotcheva, N, Genest, J, Yong, H, Urina-Triana, M, Milicic, D, Cifkova, R, Vettus, R, Koenig, W, Anker, SD, Manolis, AJ, Wyss, F, Forster, T, Sigurdsson, A, Pais, P, Fucili, A, Ogawa, H, Shimokawa, H, Veze, I, Petrauskiene, B, Salvador, L, Kastelein, J, Cornel, JH, Klemsdal, TO, Medina, F, Budaj, A, Vida-Simiti, L, Kobalava, Z, Otasevic, P, Pella, D, Lainscak, M, Seung, K-B, Commerford, P, Dellborg, M, Donath, M, Hwang, J-J, Kultursay, H, Flather, M, Ballantyne, C, Bilazarian, S, Chang, W, East, C, Everett, B, Forgosh, L, Glynn, R, Harris, B, Ligueros, M, Bohula, E, Charmarthi, B, Cheng, S, Chou, S, Danik, J, McMahon, G, Maron, B, Ning, M, Olenchock, B, Pande, R, Perlstein, T, Pradhan, A, Rost, N, Singhal, A, Taqueti, V, Wei, N, Burris, H, Cioffi, A, Dalseg, AM, Ghosh, N, Gralow, J, Mayer, T, Rugo, H, Fowler, V, Limaye, AP, Cosgrove, S, Levine, D, Lopes, R, Scott, J, Hilkert, R, Tamesby, G, Mickel, C, Manning, B, Woelcke, J, Tan, M, Manfreda, S, Ponce, T, Kam, J, Saini, R, Banker, K, Salko, T, Nandy, P, Tawfik, R, O'Neil, G, Manne, S, Jirvankar, P, Lal, S, Nema, D, Jose, J, Collins, R, Bailey, K, Blumenthal, R, Colhoun, H, and Gersh, B. "Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial." The Lancet 390, no. 10105 (October 2017): 1833-1842.  Full Text
    • Vinereanu, D, Al-Khalidi, HR, Rao, MP, He, W, Lopes, RD, Bahit, CM, Ciobanu, AO, Fox, KA, Pokorney, SD, Xian, Y, Jiang, J, Kamath, DY, Berwanger, O, Tajer, C, Huo, Y, Xavier, D, and Granger, CB. "Regional differences in presentation and antithrombotic treatment of patients with atrial fibrillation: Baseline characteristics from a clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with atrial fibrillation (IMPACT-AF)." American Heart Journal 192 (October 2017): 38-47.  Full Text
    • Vinereanu, D, Lopes, RD, Bahit, MC, Xavier, D, Jiang, J, Al-Khalidi, HR, He, W, Xian, Y, Ciobanu, AO, Kamath, DY, Fox, KA, Rao, MP, Pokorney, SD, Berwanger, O, Tajer, C, de Barros E Silva, PGM, Roettig, ML, Huo, Y, Granger, CB, and IMPACT-AF investigators, . "A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial." Lancet (London, England) 390, no. 10104 (October 2017): 1737-1746.  Full Text
    • Guimarães, PO, Granger, CB, Stebbins, A, Chiswell, K, Held, C, Hochman, JS, Krug-Gourley, S, Lonn, E, Lopes, RD, Stewart, RAH, Vinereanu, D, Wallentin, L, White, HD, Hagström, E, and Danchin, N. "Sex Differences in Clinical Characteristics, Psychosocial Factors, and Outcomes Among Patients With Stable Coronary Heart Disease: Insights from the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial." Journal of the American Heart Association 6, no. 9 (September 14, 2017).  Full Text
    • Hess, PL, Al-Khalidi, HR, Friedman, DJ, Mulder, H, Kucharska-Newton, A, Rosamond, WR, Lopes, RD, Gersh, BJ, Mark, DB, Curtis, LH, Post, WS, Prineas, RJ, Sotoodehnia, N, and Al-Khatib, SM. "The Metabolic Syndrome and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study." Journal of the American Heart Association 6, no. 8 (August 23, 2017).  Full Text
    • Vora, AN, Wang, TY, Li, S, Chiswell, K, Hess, C, Lopes, RD, Rao, SV, and Peterson, ED. "Selection of Stent Type in Patients With Atrial Fibrillation Presenting With Acute Myocardial Infarction: An Analysis From the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines." Journal of the American Heart Association 6, no. 8 (August 21, 2017).  Full Text
    • Gibson, CM, Korjian, S, Chi, G, Daaboul, Y, Jain, P, Arbetter, D, Goldhaber, SZ, Hull, R, Hernandez, AF, Lopes, RD, Gold, A, Cohen, AT, Harrington, RA, and APEX Investigators, . "Comparison of Fatal or Irreversible Events With Extended-Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy." Journal of the American Heart Association 6, no. 7 (July 11, 2017).  Full Text
    • Boonyawat, K, Caron, F, Li, A, Chai-Adisaksopha, C, Lim, W, Iorio, A, Lopes, RD, Garcia, D, and Crowther, MA. "Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and meta-analysis." Journal of Thrombosis and Haemostasis : Jth 15, no. 7 (July 2017): 1322-1333. (Review)  Full Text
    • Lopes, RD, Alings, M, Connolly, SJ, Beresh, H, Granger, CB, Mazuecos, JB, Boriani, G, Nielsen, JC, Conen, D, Hohnloser, SH, Mairesse, GH, Mabo, P, Camm, AJ, and Healey, JS. "Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial." American Heart Journal 189 (July 2017): 137-145.  Full Text
    • Manning, MW, Cooter, M, Mathew, J, Alexander, J, Peterson, E, Ferguson, TB, Lopes, R, and Podgoreanu, M. "Angiotensin Receptor Blockade Improves Cardiac Surgical Outcomes in Patients With Metabolic Syndrome." The Annals of Thoracic Surgery 104, no. 1 (July 2017): 98-105.  Full Text
    • Hijazi, Z, Lindahl, B, Oldgren, J, Andersson, U, Lindbäck, J, Granger, CB, Alexander, JH, Gersh, BJ, Hanna, M, Harjola, V-P, Hylek, EM, Lopes, RD, Siegbahn, A, and Wallentin, L. "Repeated Measurements of Cardiac Biomarkers in Atrial Fibrillation and Validation of the ABC Stroke Score Over Time." Journal of the American Heart Association 6, no. 6 (June 23, 2017).  Full Text
    • Suzumura, EA, Ribeiro, RA, Kawano-Dourado, L, de Barros E Silva, PG, Oliveira, C, Figueiró, MF, Cavalcanti, AB, Lopes, RD, and Berwanger, O. "Effects of perioperative statin use on cardiovascular complications in patients submitted to non-cardiac surgery: protocol for a systematic review, meta-analysis, and trial sequential analysis." Systematic Reviews 6, no. 1 (June 19, 2017): 116-null. (Review)  Full Text
    • Guimarães, PO, Lopes, RD, Wojdyla, DM, Abdul-Rahim, AH, Connolly, SJ, Flaker, GC, Wang, J, Hanna, M, Granger, CB, Wallentin, L, Lees, KR, Alexander, JH, and McMurray, JJV. "Effect of Apixaban on All-Cause Death in Patients with Atrial Fibrillation: a Meta-Analysis Based on Imputed Placebo Effect." Cardiovascular Drugs and Therapy 31, no. 3 (June 2017): 295-301.  Full Text
    • Lopes, RD, Guimarães, PO, Kolls, BJ, Wojdyla, DM, Bushnell, CD, Hanna, M, Easton, JD, Thomas, L, Wallentin, L, Al-Khatib, SM, Held, C, Gabriel Melo de Barros E Silva, P, Alexander, JH, Granger, CB, and Diener, H-C. "Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy." Blood 129, no. 22 (June 2017): 2980-2987.  Full Text
    • Cowper, PA, Sheng, S, Lopes, RD, Anstrom, KJ, Stafford, JA, Davidson-Ray, L, Al-Khatib, SM, Ansell, J, Dorian, P, Husted, S, McMurray, JJV, Steg, PG, Alexander, JH, Wallentin, L, Granger, CB, and Mark, DB. "Economic Analysis of Apixaban Therapy for Patients With Atrial Fibrillation From a US Perspective: Results From the ARISTOTLE Randomized Clinical Trial." Jama Cardiology 2, no. 5 (May 2017): 525-534.  Full Text
    • Hess, CN, Clare, RM, Neely, ML, Tricoci, P, Mahaffey, KW, James, SK, Alexander, JH, Held, C, Lopes, RD, Fox, KAA, White, HD, Wallentin, L, Armstrong, PW, Harrington, RA, Ohman, EM, and Roe, MT. "Differential occurrence, profile, and impact of first recurrent cardiovascular events after an acute coronary syndrome." American Heart Journal 187 (May 2017): 194-203.  Full Text
    • Vora, AN, Alexander, JH, and Lopes, RD. "Dabigatran Compared With Rivaroxaban vs Warfarin." Jama Internal Medicine 177, no. 5 (May 2017): 742-743.  Full Text
    • van Diepen, S, Merrill, PD, Carrier, M, Tardif, J-C, Podgoreanu, M, Alexander, JH, and Lopes, RD. "Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery." Journal of thrombosis and thrombolysis 43, no. 4 (May 2017): 446-453.  Full Text  Open Access Copy
    • Guimarães, PO, Lopes, RD, Stevens, SR, Zimerman, A, Wruck, L, James, SK, Haque, G, Giraldez, RRCV, Alexander, JH, and Alexander, KP. "Reporting Clinical End Points and Safety Events in an Acute Coronary Syndrome Trial: Results With Integrated Collection." Journal of the American Heart Association 6, no. 4 (April 24, 2017).  Full Text
    • Bahit, MC, Lopes, RD, Wojdyla, DM, Held, C, Hanna, M, Vinereanu, D, Hylek, EM, Verheugt, F, Goto, S, Alexander, JH, Wallentin, L, and Granger, CB. "Non-major bleeding with apixaban versus warfarin in patients with atrial fibrillation." Heart (British Cardiac Society) 103, no. 8 (April 2017): 623-628.  Full Text
    • Ducrocq, G, Schulte, PJ, Budaj, A, Cornel, JH, Held, C, Himmelmann, A, Husted, S, Storey, RF, Cannon, CP, Becker, RC, James, SK, Katus, HA, Lopes, RD, Sorbets, E, Wallentin, L, and Steg, PG. "Balancing the risk of spontaneous ischemic and major bleeding events in acute coronary syndromes." American heart journal 186 (April 2017): 91-99.  Full Text
    • Sharma, A, de Souza Brito, F, Sun, J-L, Thomas, L, Haffner, S, Holman, RR, and Lopes, RD. "Noncardiovascular deaths are more common than cardiovascular deaths in patients with cardiovascular disease or cardiovascular risk factors and impaired glucose tolerance: Insights from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial." American Heart Journal 186 (April 2017): 73-82.  Full Text
    • de Souza Brito, F, Mehta, RH, Lopes, RD, Harskamp, RE, Lucas, BD, Schulte, PJ, Tardif, J-C, and Alexander, JH. "Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery." The American Journal of Medicine 130, no. 4 (April 2017): 462-468.  Full Text
    • Hess, PL, Healey, JS, Granger, CB, Connolly, SJ, Ziegler, PD, Alexander, JH, Kowey, PR, Ruff, CT, Flaker, G, Halperin, JL, Hart, RG, and Lopes, RD. "The Role of Cardiovascular Implantable Electronic Devices in the Detection and Treatment of Subclinical Atrial Fibrillation: A Review." Jama Cardiology 2, no. 3 (March 2017): 324-331.  Full Text
    • Westenbrink, BD, Alings, M, Granger, CB, Alexander, JH, Lopes, RD, Hylek, EM, Thomas, L, Wojdyla, DM, Hanna, M, Keltai, M, Steg, PG, De Caterina, R, Wallentin, L, and van Gilst, WH. "Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial." American Heart Journal 185 (March 2017): 140-149.  Full Text
    • Armstrong, PW, Zheng, Y, Westerhout, CM, Rosell-Ortiz, F, Sinnaeve, P, Lambert, Y, Lopes, RD, Bluhmki, E, Danays, T, Van de Werf, F, and STREAM investigators, . "Corrigendum to "Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the Strategic Reperfusion Early After Myocardial infarction trial" [Am Heart J 169/6 (2015) 890-898]." American Heart Journal 184 (February 2017): 157-null.  Full Text
    • Berwanger, O, de Barros E Silva, PGM, Barbosa, RR, Precoma, DB, Figueiredo, EL, Hajjar, LA, Kruel, CDP, Alboim, C, Almeida, AP, Dracoulakis, MDA, Filho, HV, Carmona, MJC, Maia, LN, de Oliveira Filho, JB, Saraiva, JFK, Soares, RM, Damiani, L, Paisani, D, Kodama, AA, Gonzales, B, Ikeoka, DT, Devereaux, PJ, Lopes, RD, and LOAD Investigators, . "Atorvastatin for high-risk statin-naïve patients undergoing noncardiac surgery: The Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose (LOAD) randomized trial." American Heart Journal 184 (February 2017): 88-96.  Full Text
    • Tallo, FS, de Campos Vieira Abib, S, de Andrade Negri, AJ, Cesar, P, Lopes, RD, and Lopes, AC. "Evaluation of self-perception of mechanical ventilation knowledge among Brazilian final-year medical students, residents and emergency physicians." Clinics 72, no. 2 (February 2017): 65-70.  Full Text
    • Hu, PT, Lopes, RD, Stevens, SR, Wallentin, L, Thomas, L, Alexander, JH, Hanna, M, Lewis, BS, Verheugt, FWA, Granger, CB, and Jones, WS. "Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and Peripheral Artery Disease: Insights From the ARISTOTLE Trial." Journal of the American Heart Association 6, no. 1 (January 17, 2017).  Full Text
    • Harumi Higuchi Dos Santos, M, Sharma, A, Sun, J-L, Pieper, K, McMurray, JJV, Holman, RR, and Lopes, RD. "International Variation in Outcomes Among People with Cardiovascular Disease or Cardiovascular Risk Factors and Impaired Glucose Tolerance: Insights from the NAVIGATOR Trial." Journal of the American Heart Association 6, no. 1 (January 13, 2017).  Full Text
    • Guimarães, PO, Wojdyla, DM, Alexander, JH, Thomas, L, Alings, M, Flaker, GC, Al-Khatib, SM, Hanna, M, Horowitz, JD, Wallentin, L, Granger, CB, and Lopes, RD. "Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial." International Journal of Cardiology 227 (January 2017): 443-449.  Full Text
    • Dupre, ME, and Lopes, RD. "Marital History and Survival After Stroke." Journal of the American Heart Association 5, no. 12 (December 14, 2016).  Full Text
    • Cornel, JH, Bakris, GL, Stevens, SR, Alvarsson, M, Bax, WA, Chuang, L-M, Engel, SS, Lopes, RD, McGuire, DK, Riefflin, A, Rodbard, HW, Sinay, I, Tankova, T, Wainstein, J, Peterson, ED, Holman, RR, and TECOS Study Group, . "Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOS." Diabetes Care 39, no. 12 (December 2016): 2304-2310.  Full Text
    • Katz, M, Bosworth, HB, Lopes, RD, Dupre, ME, Morita, F, Pereira, C, Franco, FGM, Prado, RR, Pesaro, AE, and Wajngarten, M. "A time-series analysis of the relation between unemployment rate and hospital admission for acute myocardial infarction and stroke in Brazil over more than a decade." International journal of cardiology 224 (December 2016): 33-36.  Full Text
    • Li, G, Thabane, L, Cook, DJ, Lopes, RD, Marshall, JC, Guyatt, G, Holbrook, A, Akhtar-Danesh, N, Fowler, RA, Adhikari, NKJ, Taylor, R, Arabi, YM, Chittock, D, Dodek, P, Freitag, AP, Walter, SD, Heels-Ansdell, D, and Levine, MAH. "Risk factors for and prediction of mortality in critically ill medical-surgical patients receiving heparin thromboprophylaxis." Annals of Intensive Care 6, no. 1 (December 2016): 18-null.  Full Text
    • Gomes, WJ, Leal, JC, Braile, DM, Guimarães, JA, Lopes, RD, Lima, MA, and Nader, HB. "A Brazilian perspective for the use of bovine heparin in open heart surgery." International journal of cardiology 223 (November 2016): 611-612. (Letter)  Full Text
    • Oldgren, J, Hijazi, Z, Lindbäck, J, Alexander, JH, Connolly, SJ, Eikelboom, JW, Ezekowitz, MD, Granger, CB, Hylek, EM, Lopes, RD, Siegbahn, A, Yusuf, S, Wallentin, L, and RE-LY and ARISTOTLE Investigators, . "Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation." Circulation 134, no. 22 (November 2016): 1697-1707.  Full Text
    • Piccaro de Oliveira, P, Gonzales, V, Lopes, RD, Schmidt, MM, Garofallo, S, Santos, RPD, Carrion, L, Gottschall, C, and Quadros, AS. "Serious infections among unselected patients with ST-elevation myocardial infarction treated with contemporary primary percutaneous coronary intervention." American heart journal 181 (November 2016): 52-59.  Full Text
    • Li, G, Cook, DJ, Thabane, L, Friedrich, JO, Crozier, TM, Muscedere, J, Granton, J, Mehta, S, Reynolds, SC, Lopes, RD, Lauzier, F, Freitag, AP, Levine, MAH, PROTECT Investigators for the Canadian Critical Care Trials Group, , and Australian and New Zealand Intensive Care Society Clinical Trials Group, . "Erratum to: Risk factors for mortality in patients admitted to intensive care units with pneumonia." Respiratory Research 17, no. 1 (October 7, 2016): 128-null.  Full Text
    • Li, A, Lopes, RD, and Garcia, DA. "Use of Direct Oral Anticoagulants in Special Populations." Hematology/Oncology Clinics of North America 30, no. 5 (October 2016): 1053-1071. (Review)  Full Text
    • Sandhu, RK, Ezekowitz, J, Andersson, U, Alexander, JH, Granger, CB, Halvorsen, S, Hanna, M, Hijazi, Z, Jansky, P, Lopes, RD, and Wallentin, L. "The 'obesity paradox' in atrial fibrillation: observations from the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) trial." European Heart Journal 37, no. 38 (October 2016): 2869-2878.  Full Text
    • Alexander, JH, Andersson, U, Lopes, RD, Hijazi, Z, Hohnloser, SH, Ezekowitz, JA, Halvorsen, S, Hanna, M, Commerford, P, Ruzyllo, W, Huber, K, Al-Khatib, SM, Granger, CB, Wallentin, L, and Apixaban for Reduction of Stroke and Other Thromboembolic Complications in Atrial Fibrillation (ARISTOTLE) Investigators, . "Apixaban 5 mg Twice Daily and Clinical Outcomes in Patients With Atrial Fibrillation and Advanced Age, Low Body Weight, or High Creatinine: A Secondary Analysis of a Randomized Clinical Trial." Jama Cardiology 1, no. 6 (September 2016): 673-681.  Full Text
    • Jackson, LR, Piccini, JP, Cyr, DD, Roe, MT, Neely, ML, Martinez, F, Lüscher, TF, Lopes, RD, Winters, KJ, White, HD, Armstrong, PW, Fox, KAA, Prabhakaran, D, Bhatt, DL, Magnus Ohman, E, and Corbalán, R. "Dual Antiplatelet Therapy and Outcomes in Patients With Atrial Fibrillation and Acute Coronary Syndromes Managed Medically Without Revascularization: Insights From the TRILOGY ACS Trial." Clinical Cardiology 39, no. 9 (September 2016): 497-506.  Full Text
    • Armaganijan, LV, Alexander, KP, Huang, Z, Tricoci, P, Held, C, Van de Werf, F, Armstrong, PW, Aylward, PE, White, HD, Moliterno, DJ, Wallentin, L, Chen, E, Harrington, RA, Strony, J, Mahaffey, KW, and Lopes, RD. "Effect of age on efficacy and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial." American Heart Journal 178 (August 2016): 176-184.  Full Text
    • Fitzmaurice, DA, Accetta, G, Haas, S, Kayani, G, Lucas Luciardi, H, Misselwitz, F, Pieper, K, Ten Cate, H, Turpie, AGG, Kakkar, AK, and GARFIELD-AF Investigators, . "Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists." British Journal of Haematology 174, no. 4 (August 2016): 610-623.  Full Text
    • Hess, PL, Lopes, RD, and Healey, JS. "Letter by Hess et al Regarding Article, "How to Manage Occult Atrial Fibrillation Detected on Long-Term Monitoring"." Circulation 134, no. 5 (August 2016): e28-e29. (Letter)  Full Text
    • Jardim, PCBV, Souza, WKSBD, Lopes, RD, Brandão, AA, Malachias, MVB, Gomes, MM, Moreno Júnior, H, Barbosa, ECD, and Póvoa, RMDS. "I RBH - First Brazilian Hypertension Registry." Arquivos brasileiros de cardiologia 107, no. 2 (August 2016): 93-98.  Full Text
    • Li, G, Cook, DJ, Thabane, L, Friedrich, JO, Crozier, TM, Muscedere, J, Granton, J, Mehta, S, Reynolds, SC, Lopes, RD, Lauzier, F, Freitag, AP, Levine, MAH, PROTECT Investigators for the Canadian Critical Care Trials Group, and and the Australian and New Zealand Intensive Care Society Clinical Trials Group, . "Risk factors for mortality in patients admitted to intensive care units with pneumonia." Respiratory Research 17, no. 1 (July 11, 2016): 80-null.  Full Text
    • Hijazi, Z, Hohnloser, SH, Andersson, U, Alexander, JH, Hanna, M, Keltai, M, Parkhomenko, A, López-Sendón, JL, Lopes, RD, Siegbahn, A, Granger, CB, and Wallentin, L. "Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time: Insights From the ARISTOTLE Randomized Clinical Trial." Jama Cardiology 1, no. 4 (July 2016): 451-460.  Full Text
    • Shimada, YJ, Bansilal, S, Wiviott, SD, Becker, RC, Harrington, RA, Himmelmann, A, Neely, B, Husted, S, James, SK, Katus, HA, Lopes, RD, Steg, PG, Storey, RF, Wallentin, L, Cannon, CP, and PLATO Investigators, . "Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial." American Heart Journal 177 (July 2016): 1-8.  Full Text
    • Lopes, RD, Pieper, KS, Stevens, SR, Solomon, SD, McMurray, JJV, Pfeffer, MA, Leimberger, JD, and Velazquez, EJ. "Predicting Outcomes Over Time in Patients With Heart Failure, Left Ventricular Systolic Dysfunction, or Both Following Acute Myocardial Infarction." Journal of the American Heart Association 5, no. 6 (June 27, 2016).  Full Text  Open Access Copy
    • Jaspers Focks, J, Brouwer, MA, Wojdyla, DM, Thomas, L, Lopes, RD, Washam, JB, Lanas, F, Xavier, D, Husted, S, Wallentin, L, Alexander, JH, Granger, CB, and Verheugt, FWA. "Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial." Bmj (Clinical Research Ed.) 353 (June 15, 2016): i2868-null.  Full Text
    • Bahit, MC, Coppola, ML, Riccio, PM, Cipriano, LE, Roth, GA, Lopes, RD, Feigin, VL, Borrego Guerrero, B, De Martino, M, Díaz, A, Ferrante, D, Funaro, F, Lavados, P, Lewin, ML, López, DH, Macarrone, P, Marciello, R, Marino, D, Martens, C, Martínez, P, Odriozola, G, Rabinstein, AA, Saposnik, G, Silva, D, Suasnabar, R, Truelsen, T, Uzcudun, A, Viviani, CA, and Sposato, LA. "First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina." Stroke 47, no. 6 (June 2016): 1640-1642.  Full Text
    • Hijazi, Z, Oldgren, J, Lindbäck, J, Alexander, JH, Connolly, SJ, Eikelboom, JW, Ezekowitz, MD, Held, C, Hylek, EM, Lopes, RD, Siegbahn, A, Yusuf, S, Granger, CB, Wallentin, L, and ARISTOTLE and RE-LY Investigators, . "The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study." Lancet (London, England) 387, no. 10035 (June 2016): 2302-2311.  Full Text
    • Lopes, RD, Rao, M, Simon, DN, Thomas, L, Ansell, J, Fonarow, GC, Gersh, BJ, Go, AS, Hylek, EM, Kowey, P, Piccini, JP, Singer, DE, Chang, P, Peterson, ED, and Mahaffey, KW. "Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease." The American Journal of Medicine 129, no. 6 (June 2016): 592-599.e1.  Full Text
    • Lopes, RD, de Paola, AAV, Lorga Filho, AM, Consolim-Colombo, FM, Andrade, J, Piva E Mattos, LA, Bernardez-Pereira, S, Berwanger, O, de Oliveira Figueiredo, MJ, and RECALL Steering Committee and Investigators, . "Rationale and design of the First Brazilian Cardiovascular Registry of Atrial Fibrillation: The RECALL study." American heart journal 176 (June 2016): 10-16.  Full Text
    • Rao, MP, Ciobanu, AO, Lopes, RD, Fox, KA, Xian, Y, Pokorney, SD, Al-Khalidi, HR, Jiang, J, Kamath, DY, Berwanger, O, Xavier, D, Bahit, CM, Tajer, C, Vinereanu, D, Huo, Y, and Granger, CB. "A clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AF): design and rationale." American heart journal 176 (June 2016): 107-113.  Full Text
    • De Caterina, R, Andersson, U, Alexander, JH, Al-Khatib, SM, Bahit, MC, Goto, S, Hanna, M, Held, C, Hohnloser, S, Hylek, EM, Lanas, F, Lopes, RD, López-Sendón, J, Renda, G, Horowitz, J, Granger, CB, Wallentin, L, and ARISTOTLE Investigators, . "History of bleeding and outcomes with apixaban versus warfarin in patients with atrial fibrillation in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial." American Heart Journal 175 (May 2016): 175-183.  Full Text
    • Harskamp, RE, Alexander, JH, Ferguson, TB, Hager, R, Mack, MJ, Englum, B, Wojdyla, D, Schulte, PJ, Kouchoukos, NT, de Winter, RJ, Gibson, CM, Peterson, ED, Harrington, RA, Smith, PK, and Lopes, RD. "Response to Letters Regarding Article, "Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial"." Circulation 133, no. 21 (May 2016): e665-null. (Letter)  Full Text
    • Hijazi, Z, Lindbäck, J, Alexander, JH, Hanna, M, Held, C, Hylek, EM, Lopes, RD, Oldgren, J, Siegbahn, A, Stewart, RAH, White, HD, Granger, CB, Wallentin, L, and ARISTOTLE and STABILITY Investigators, . "The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation." European Heart Journal 37, no. 20 (May 2016): 1582-1590.  Full Text
    • McGuire, DK, Van de Werf, F, Armstrong, PW, Standl, E, Koglin, J, Green, JB, Bethel, MA, Cornel, JH, Lopes, RD, Halvorsen, S, Ambrosio, G, Buse, JB, Josse, RG, Lachin, JM, Pencina, MJ, Garg, J, Lokhnygina, Y, Holman, RR, Peterson, ED, and Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS) Study Group, . "Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial." Jama Cardiology 1, no. 2 (May 2016): 126-135.  Full Text
    • Ruff, CT, Ansell, JE, Becker, RC, Benjamin, EJ, Deicicchi, DJ, Mark Estes, NA, Ezekowitz, MD, Fanikos, J, Fareed, J, Garcia, D, Giugliano, RP, Goldhaber, SZ, Granger, C, Healey, JS, Hull, R, Hylek, EM, Libby, P, Lopes, RD, Mahaffey, KW, Mega, J, Piazza, G, Sasahara, AA, Sorond, FA, Spyropoulos, AC, Walenga, JM, and Weitz, JI. "North American Thrombosis Forum, AF Action Initiative Consensus Document." The American Journal of Medicine 129, no. 5 Suppl (May 2016): S1-S29.  Full Text
    • Kragholm, K, Goldstein, SA, Yang, Q, Lopes, RD, Schulte, PJ, Bernacki, GM, White, HD, Mahaffey, KW, Giugliano, RP, Armstrong, PW, Harrington, RA, Tricoci, P, Van de Werf, F, Alexander, JH, Alexander, KP, and Newby, LK. "Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials." CIRCULATION 133, no. 16 (April 19, 2016): 1560-+.  Full Text  Link to Item
    • Hijazi, Z, Aulin, J, Andersson, U, Alexander, JH, Gersh, B, Granger, CB, Hanna, M, Horowitz, J, Hylek, EM, Lopes, RD, Siegbahn, A, Wallentin, L, and ARISTOTLE Investigators, . "Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation." Heart (British Cardiac Society) 102, no. 7 (April 2016): 508-517.  Full Text
    • Kragholm, K, Goldstein, SA, Yang, Q, Lopes, RD, Schulte, PJ, Bernacki, GM, White, HD, Mahaffey, KW, Giugliano, RP, Armstrong, PW, Harrington, RA, Tricoci, P, Van de Werf, F, Alexander, JH, Alexander, KP, and Newby, LK. "Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials." Circulation 133, no. 16 (April 2016): 1560-1573.  Full Text
    • Prates, PRL, Williams, JB, Mehta, RH, Stevens, SR, Thomas, L, Smith, PK, Newby, LK, Kalil, RAK, Alexander, JH, and Lopes, RD. "Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate." Brazilian journal of cardiovascular surgery 31, no. 2 (April 2016): 106-114.  Full Text  Open Access Copy
    • Streiff, MB, Agnelli, G, Connors, JM, Crowther, M, Eichinger, S, Lopes, RD, McBane, RD, Moll, S, and Ansell, J. "Erratum to: Guidance for the treatment of deep vein thrombosis and pulmonary embolism." Journal of Thrombosis and Thrombolysis 41, no. 3 (April 2016): 548-null.  Full Text
    • Zimerman, A, Lopes, RD, Stebbins, AL, Guimarães, PO, Haque, G, Melloni, C, Trollinger, K, James, SK, Alexander, JH, Tricoci, P, Roe, MT, Ohman, EM, Mahaffey, KW, Held, C, Tinga, B, Pieper, KS, and Alexander, KP. "Pooled analysis of adverse event collection from 4 acute coronary syndrome trials." American Heart Journal 174 (April 2016): 60-67.  Full Text
    • Lopes, RD, Leonardi, S, Neely, B, Neely, ML, Ohman, EM, Ardissino, D, Hamm, CW, Goodman, SG, Bhatt, DL, White, HD, Prabhakaran, D, Martinez, F, Nicolau, JC, Winters, KJ, Fox, KAA, Armstrong, PW, and Roe, MT. "Spontaneous MI After Non-ST-Segment Elevation Acute Coronary Syndrome Managed Without Revascularization: The TRILOGY ACS Trial." Journal of the American College of Cardiology 67, no. 11 (March 2016): 1289-1297.  Full Text
    • Rajpurohit, N, Gulati, R, Lennon, RJ, Singh, M, Rihal, CS, Santrach, PJ, Donato, LJ, Karon, BS, Del-Carpio, F, Tak, T, Motiei, A, Lopes, RD, and Gharacholou, SM. "Relation of Activated Clotting Times During Percutaneous Coronary Intervention to Outcomes." The American journal of cardiology 117, no. 5 (March 2016): 703-708.  Full Text
    • Vavalle, JP, van Diepen, S, Clare, RM, Hochman, JS, Weaver, WD, Mehta, RH, Pieper, KS, Patel, MR, Patel, UD, Armstrong, PW, Granger, CB, and Lopes, RD. "Renal failure in patients with ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention: Predictors, clinical and angiographic features, and outcomes." American Heart Journal 173 (March 2016): 57-66.  Full Text
    • Pesaro, AEP, Granger, CB, and Lopes, RD. "Reduction of ischemic events in Improved Reduction of Outcomes: Vytorin Efficacy International Trial: Intensive cholesterol lowering or ezetimibe antithrombotic effects?." American Heart Journal 172 (February 2016): 42-44.  Full Text
    • Sebben, JC, Pinto Ribeiro, DR, Lopes, RD, de Winter, R, Harskamp, R, Cambruzzi, E, Schmidt, MM, Martinelli, ES, Gottschall, CA, and Quadros, AS. "The role of diabetes mellitus in the composition of coronary thrombi in patients presenting with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention." American Heart Journal 172 (February 2016): 26-33.  Full Text
    • Durheim, MT, Cyr, DD, Lopes, RD, Thomas, LE, Tsuang, WM, Gersh, BJ, Held, C, Wallentin, L, Granger, CB, Palmer, SM, and Al-Khatib, SM. "Chronic obstructive pulmonary disease in patients with atrial fibrillation: Insights from the ARISTOTLE trial." International Journal of Cardiology 202 (January 2016): 589-594.  Full Text
    • Harskamp, RE, Alexander, JH, Ferguson, TB, Hager, R, Mack, MJ, Englum, B, Wojdyla, D, Schulte, PJ, Kouchoukos, NT, de Winter, RJ, Gibson, CM, Peterson, ED, Harrington, RA, Smith, PK, and Lopes, RD. "Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial." Circulation 133, no. 2 (January 2016): 131-138.  Full Text
    • Lincoff, AM, Mehran, R, Povsic, TJ, Zelenkofske, SL, Huang, Z, Armstrong, PW, Steg, PG, Bode, C, Cohen, MG, Buller, C, Laanmets, P, Valgimigli, M, Marandi, T, Fridrich, V, Cantor, WJ, Merkely, B, Lopez-Sendon, J, Cornel, JH, Kasprzak, JD, Aschermann, M, Guetta, V, Morais, J, Sinnaeve, PR, Huber, K, Stables, R, Sellers, MA, Borgman, M, Glenn, L, Levinson, AI, Lopes, RD, Hasselblad, V, Becker, RC, Alexander, JH, and REGULATE-PCI Investigators, . "Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial." Lancet (London, England) 387, no. 10016 (January 2016): 349-356.  Full Text
    • Pesaro, AEP, Katz, M, Katz, JN, Barbas, CSV, Makdisse, MR, Correa, AG, Franken, M, Pereira, C, Serrano, CV, and Lopes, RD. "Mechanical Ventilation and Clinical Outcomes in Patients with Acute Myocardial Infarction: A Retrospective Observational Study." PloS one 11, no. 3 (January 2016): e0151302-.  Full Text
    • Streiff, MB, Agnelli, G, Connors, JM, Crowther, M, Eichinger, S, Lopes, R, McBane, RD, Moll, S, and Ansell, J. "Guidance for the treatment of deep vein thrombosis and pulmonary embolism." Journal of Thrombosis and Thrombolysis 41, no. 1 (January 2016): 32-67. (Review)  Full Text
    • Rao, MP, Halvorsen, S, Wojdyla, D, Thomas, L, Alexander, JH, Hylek, EM, Hanna, M, Bahit, MC, Lopes, RD, De Caterina, R, Erol, C, Goto, S, Lanas, F, Lewis, BS, Husted, S, Gersh, BJ, Wallentin, L, Granger, CB, and Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Steering Committee and Investigators, . "Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial." Journal of the American Heart Association 4, no. 12 (December 2015).  Full Text
    • Vinereanu, D, Stevens, SR, Alexander, JH, Al-Khatib, SM, Avezum, A, Bahit, MC, Granger, CB, Lopes, RD, Halvorsen, S, Hanna, M, Husted, S, Hylek, EM, Mărgulescu, AD, Wallentin, L, and Atar, D. "Clinical outcomes in patients with atrial fibrillation according to sex during anticoagulation with apixaban or warfarin: a secondary analysis of a randomized controlled trial." European Heart Journal 36, no. 46 (December 2015): 3268-3275.  Full Text
    • Khan, R, Lopes, RD, Neely, ML, Stevens, SR, Harrington, RA, Diaz, R, Cools, F, Jansky, P, Montalescot, G, Atar, D, Lopez-Sendon, J, Flather, M, Liaw, D, Wallentin, L, Alexander, JH, Goodman, SG, and Apixaban for Prevention of Acute Ischemic Safety Events (APPRAISE)-2 Steering Committee and Investigators, . "Characterising and predicting bleeding in high-risk patients with an acute coronary syndrome." Heart (British Cardiac Society) 101, no. 18 (September 2015): 1475-1484.  Full Text
    • Avezum, A, Lopes, RD, Schulte, PJ, Lanas, F, Gersh, BJ, Hanna, M, Pais, P, Erol, C, Diaz, R, Cecilia Bahit, M, Bartunek, J, De Caterina, R, Goto, S, Ruzyllo, W, Zhu, J, Granger, CB, and Alexander, JH. "Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial." CIRCULATION 132, no. 8 (August 25, 2015): 624-632.  Full Text  Link to Item
    • Harskamp, RE, Vassiliades, TA, Mehta, RH, de Winter, RJ, Lopes, RD, Xian, Y, Peterson, ED, Puskas, JD, and Halkos, ME. "Comparative Effectiveness of Hybrid Coronary Revascularization vs Coronary Artery Bypass Grafting." Journal of the American College of Surgeons 221, no. 2 (August 2015): 326-34.e1.  Full Text
    • Hess, CN, James, S, Lopes, RD, Wojdyla, DM, Neely, ML, Liaw, D, Hagstrom, E, Bhatt, DL, Husted, S, Goodman, SG, Lewis, BS, Verheugt, FWA, De Caterina, R, Ogawa, H, Wallentin, L, and Alexander, JH. "Apixaban Plus Mono Versus Dual Antiplatelet Therapy in Acute Coronary Syndromes: Insights From the APPRAISE-2 Trial." Journal of the American College of Cardiology 66, no. 7 (August 2015): 777-787.  Full Text
    • Healey, JS, Lopes, RD, and Connolly, SJ. "The detection and treatment of subclinical atrial fibrillation: evaluating the IMPACT of a comprehensive strategy based on remote arrhythmia monitoring." European heart journal 36, no. 26 (July 2015): 1640-1642.  Full Text
    • Hess, CN, Lopes, RD, Gibson, CM, Hager, R, Wojdyla, DM, Englum, BR, Mack, MJ, Kouchoukos, NT, Peterson, ED, and Alexander, JH. "Response to Letters Regarding Article, "Saphenous Vein Graft Failure After Coronary Artery Bypass Surgery: Insights From PREVENT IV"." Circulation 132, no. 4 (July 2015): e29-null. (Letter)  Full Text
    • Williams, JB, Harskamp, RE, Bose, S, Lawson, JH, Alexander, JH, Smith, PK, and Lopes, RD. "The Preservation and Handling of Vein Grafts in Current Surgical Practice: Findings of a Survey Among Cardiovascular Surgeons of Top-Ranked US Hospitals." Jama Surgery 150, no. 7 (July 2015): 681-683.  Full Text
    • Mahaffey, KW, Hager, R, Wojdyla, D, White, HD, Armstrong, PW, Alexander, JH, Tricoci, P, Lopes, RD, Ohman, EM, Roe, MT, Harrington, RA, and Wallentin, L. "Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes." Journal of the American Heart Association 4, no. 6 (June 18, 2015): e001512-null.  Full Text
    • Albuquerque, DCD, Neto, JDDS, Bacal, F, Rohde, LEP, Bernardez-Pereira, S, Berwanger, O, Almeida, DR, and Investigadores Estudo BREATHE, . "I Brazilian Registry of Heart Failure - Clinical Aspects, Care Quality and Hospitalization Outcomes." Arquivos brasileiros de cardiologia 104, no. 6 (June 2015): 433-442.  Full Text
    • Armaganijan, LV, Staico, R, Moreira, DAR, Lopes, RD, Medeiros, PTJ, Habib, R, Melo Neto, J, Katz, M, Armaganijan, D, Sousa, AGMR, Mahfoud, F, and Abizaid, A. "6-Month Outcomes in Patients With Implantable Cardioverter-Defibrillators Undergoing Renal Sympathetic Denervation for the Treatment of Refractory Ventricular Arrhythmias." Jacc. Cardiovascular Interventions 8, no. 7 (June 2015): 984-990.  Full Text
    • Armstrong, PW, Zheng, Y, Westerhout, CM, Rosell-Ortiz, F, Sinnaeve, P, Lambert, Y, Lopes, RD, Bluhmki, E, Danays, T, Van de Werf, F, and STREAM investigators, . "Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the STrategic Reperfusion Early After Myocardial infarction trial." American heart journal 169, no. 6 (June 2015): 890-898.e1.  Full Text
    • Lopes, RD, Gharacholou, SM, Holmes, DN, Thomas, L, Wang, TY, Roe, MT, Peterson, ED, and Alexander, KP. "Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI." The American journal of medicine 128, no. 6 (June 2015): 582-590.  Full Text
    • Ciobanu, AO, Bennett, S, Lopes, RD, and Vinereanu, D. "Isolated Double Orifice Mitral Valve - a Rare Finding in an Elderly Man." Arquivos brasileiros de cardiologia 104, no. 5 (May 2015): e53-e54.  Full Text
    • Held, C, Hylek, EM, Alexander, JH, Hanna, M, Lopes, RD, Wojdyla, DM, Thomas, L, Al-Khalidi, H, Alings, M, Xavier, D, Ansell, J, Goto, S, Ruzyllo, W, Rosenqvist, M, Verheugt, FWA, Zhu, J, Granger, CB, and Wallentin, L. "Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial." European Heart Journal 36, no. 20 (May 2015): 1264-1272.  Full Text
    • "Correction." American Heart Journal 169, no. 4 (April 2015): 594-594.  Full Text
    • Cornel, JH, Lopes, RD, James, S, Stevens, SR, Neely, ML, Liaw, D, Miller, J, Mohan, P, Amerena, J, Raev, D, Huo, Y, Urina-Triana, M, Gallegos Cazorla, A, Vinereanu, D, Fridrich, V, Harrington, RA, Wallentin, L, Alexander, JH, and APPRAISE-2 Study Group, . "Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial." American heart journal 169, no. 4 (April 2015): 531-538.  Full Text
    • Ezekowitz, JA, Lewis, BS, Lopes, RD, Wojdyla, DM, McMurray, JJV, Hanna, M, Atar, D, Cecilia Bahit, M, Keltai, M, Lopez-Sendon, JL, Pais, P, Ruzyllo, W, Wallentin, L, Granger, CB, and Alexander, JH. "Clinical outcomes of patients with diabetes and atrial fibrillation treated with apixaban: results from the ARISTOTLE trial." European Heart Journal. Cardiovascular Pharmacotherapy 1, no. 2 (April 2015): 86-94.  Full Text
    • Harskamp, RE, Halkos, ME, Xian, Y, Szerlip, MA, Poston, RS, Mick, SL, Lopes, RD, Tijssen, JG, de Winter, RJ, and Peterson, ED. "A nationwide survey on perception, experience, and expectations of hybrid coronary revascularization among top-ranked US hospitals." American heart journal 169, no. 4 (April 2015): 557-63.e6.  Full Text
    • Katz, M, Califf, RM, Sun, J-L, McMurray, JJV, Thomas, L, and Lopes, RD. "Venous thromboembolism and cardiovascular risk: results from the NAVIGATOR trial." The American Journal of Medicine 128, no. 3 (March 2015): 297-302.  Full Text
    • Krishnamoorthy, A, Sherwood, MW, Lopes, RD, and Becker, RC. "The periprocedural management of novel oral anticoagulants in patients with nonvalvular atrial fibrillation: rationale and a summary of the available evidence from phase 3 clinical trials." American Heart Journal 169, no. 3 (March 2015): 315-322. (Review)  Full Text
    • Hijazi, Z, Siegbahn, A, Andersson, U, Lindahl, B, Granger, CB, Alexander, JH, Atar, D, Gersh, BJ, Hanna, M, Harjola, V-P, Horowitz, J, Husted, S, Hylek, EM, Lopes, RD, McMurray, JJV, and Wallentin, L. "Comparison of cardiac troponins I and T measured with high-sensitivity methods for evaluation of prognosis in atrial fibrillation: an ARISTOTLE substudy." Clinical chemistry 61, no. 2 (February 2015): 368-378.  Full Text
    • Putera, M, Roark, R, Lopes, RD, Udayakumar, K, Peterson, ED, Califf, RM, and Shah, BR. "Translation of acute coronary syndrome therapies: from evidence to routine clinical practice." American Heart Journal 169, no. 2 (February 2015): 266-273.  Full Text
    • Cornel, JH, Lopes, RD, James, S, Stevens, SR, Neely, ML, Liaw, D, Miller, J, Mohan, P, Amerena, J, Raev, D, Huo, Y, Urina-Triana, M, Gallegos Cazorla, A, Vinereanu, D, Fridrich, V, Harrington, RA, Wallentin, L, and Alexander, JH. "Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial." American Heart Journal 169, no. 4 (January 1, 2015): 531-538.  Full Text
    • Granger, CB, Lopes, RD, Hanna, M, Ansell, J, Hylek, EM, Alexander, JH, Thomas, L, Wang, J, Bahit, MC, Verheugt, F, Lawrence, J, Xavier, D, and Wallentin, L. "Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial." American heart journal 169, no. 1 (January 2015): 25-30.  Full Text
    • Guimarães, PO, Kaatz, S, and Lopes, RD. "Practical and clinical considerations in assessing patients with atrial fibrillation for switching to non-vitamin K antagonist oral anticoagulants in primary care." International journal of general medicine 8 (January 2015): 283-291. (Review)  Full Text
    • Harskamp, RE, Halkos, ME, Xian, Y, Szerlip, MA, Poston, RS, Mick, SL, Lopes, RD, Tijssen, JG, De Winter, RJ, and Peterson, ED. "A nationwide survey on perception, experience, and expectations of hybrid coronary revascularization among top-ranked US hospitals." American Heart Journal 169, no. 4 (January 1, 2015): 557-563.e6.  Full Text
    • Katz, M, Califf, RM, Sun, JL, McMurray, JJV, Thomas, L, and Lopes, RD. "Venous thromboembolism and cardiovascular risk: Results from the NAVIGATOR trial." American Journal of Medicine 128, no. 3 (January 1, 2015): 297-302.  Full Text
    • Khan, R, Lopes, RD, Neely, ML, Stevens, SR, Harrington, RA, Diaz, R, Cools, F, Jansky, P, Montalescot, G, Atar, D, Lopez-Sendon, J, Flather, M, Liaw, D, Wallentin, L, Alexander, JH, and Goodman, SG. "Characterising and predicting bleeding in high-risk patients with an acute coronary syndrome." Heart (2015).  Full Text
    • Koshizaka, M, Lopes, RD, Reyes, EM, Gibson, CM, Schulte, PJ, Hafley, GE, Hernandez, AF, Green, JB, Kouchoukos, NT, Califf, RM, Ferguson, TB, Peterson, ED, and Alexander, JH. "Long-term clinical and angiographic outcomes in patients with diabetes undergoing coronary artery bypass graft surgery: results from the Project of Ex-vivo Vein Graft Engineering via Transfection IV trial." American Heart Journal 169, no. 1 (January 2015): 175-184.  Full Text
    • Nutescu, EA, Wittkowsky, AK, Witt, DM, Kaatz, S, Ansell, J, Burnett, A, Garcia, D, Lopes, RD, Oertel, L, Schnurr, T, Streiff, M, Wirth, D, and Crowther, M. "Integrating electronic health records in the delivery of optimized anticoagulation therapy." The Annals of Pharmacotherapy 49, no. 1 (January 2015): 125-126.  Full Text
    • Welsh, RC, Van De Werf, F, Westerhout, CM, Goldstein, P, Gershlick, AH, Wilcox, RG, Danays, T, Bluhmki, E, Lopes, RD, Steg, PG, and Armstrong, PW. "Outcomes of a pharmacoinvasive strategy for successful versus failed fibrinolysis and primary percutaneous intervention in acute myocardial infarction (from the strategic reperfusion early after myocardial infarction [STREAM] study)." American Journal of Cardiology 114, no. 6 (January 1, 2015): 811-819.  Full Text
    • Garcia, D, Alexander, JH, Wallentin, L, Wojdyla, DM, Thomas, L, Hanna, M, Al-Khatib, SM, Dorian, P, Ansell, J, Commerford, P, Flaker, G, Lanas, F, Vinereanu, D, Xavier, D, Hylek, EM, Held, C, Verheugt, FWA, Granger, CB, and Lopes, RD. "Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures." Blood 124, no. 25 (December 2014): 3692-3698.  Full Text
    • Gracieux, J, Sanders, GD, Pokorney, SD, Lopes, RD, Thomas, K, and Al-Khatib, SM. "Incidence and predictors of appropriate therapies delivered by the implantable cardioverter defibrillator in patients with ischemic cardiomyopathy: a systematic review." International journal of cardiology 177, no. 3 (December 2014): 990-994. (Review)  Full Text
    • Harskamp, RE, Abdelsalam, M, Lopes, RD, Boga, G, Hirji, S, Krishnan, M, Kiljanek, L, Mumtaz, M, Tijssen, JG, McCarty, C, de Winter, RJ, and Bachinsky, WB. "Cardiac troponin release following hybrid coronary revascularization versus off-pump coronary artery bypass surgery." Interactive Cardiovascular and Thoracic Surgery 19, no. 6 (December 2014): 1008-1012.  Full Text
    • Hohnloser, SH, and Lopes, RD. "Atrial fibrillation, valvular heart disease, and use of target-specific oral anticoagulants for stroke prevention." European heart journal 35, no. 47 (December 2014): 3323-3325.  Full Text
    • Harskamp, RE, Schulte, PJ, Alexander, JH, and Lopes, RD. "Reply: To PMID 24360877." The Annals of thoracic surgery 98, no. 5 (November 2014): 1890-. (Letter)  Full Text
    • Harskamp, RE, Schulte, PJ, Alexander, JH, and Lopes, RD. "About the Impact of Extracardiac Vascular Disease on Vein Graft Failure Reply." ANNALS OF THORACIC SURGERY 98, no. 5 (November 2014): 1890-1890.  Full Text  Link to Item
    • Harskamp, RE, Williams, JB, Halkos, ME, Lopes, RD, Tijssen, JGP, Ferguson, TB, and De Winter, RJ. "Meta-analysis of minimally invasive coronary artery bypass versus drug-eluting stents for isolated left anterior descending coronary artery disease." Journal of Thoracic and Cardiovascular Surgery 148, no. 5 (November 1, 2014): 1837-1842.  Full Text
    • Harskamp, RE, Williams, JB, Halkos, ME, Lopes, RD, Tijssen, JGP, Ferguson, TB, and de Winter, RJ. "Meta-analysis of minimally invasive coronary artery bypass versus drug-eluting stents for isolated left anterior descending coronary artery disease." The Journal of thoracic and cardiovascular surgery 148, no. 5 (November 2014): 1837-1842. (Review)  Full Text
    • Wallentin, L, Hijazi, Z, Andersson, U, Alexander, JH, De Caterina, R, Hanna, M, Horowitz, JD, Hylek, EM, Lopes, RD, Asberg, S, Granger, CB, Siegbahn, A, and ARISTOTLE Investigators, . "Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial." Circulation 130, no. 21 (November 2014): 1847-1858.  Full Text
    • Ansell, J, Crowther, M, Burnett, A, Garcia, D, Kaatz, S, Lopes, RD, Nutescu, E, Oertel, L, Schnurr, T, Streiff, M, Wirth, D, Witt, D, Wittkowsky, A, and Anticoagulation Forum, . "Comment on: editorial by Husted et al. "Non-vitamin K antagonist oral anticoagulants (NOACs): no longer new or novel". (Thromb Haemost 2014; 111: 781-782)." Thrombosis and haemostasis 112, no. 4 (October 2014): 841-. (Letter)  Full Text
    • Bagai, A, Schulte, PJ, Granger, CB, Mahaffey, KW, Christenson, RH, Bell, G, Lopes, RD, Green, CL, Lincoff, AM, Armstrong, PW, and Roe, MT. "Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention." American heart journal 168, no. 4 (October 2014): 503-511.e2.  Full Text
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    • Testoni, D, Hayashi, M, Cohen-Wolkowiez, M, Benjamin, DK, Lopes, RD, Clark, RH, and Smith, PB. "Late-onset bloodstream infections in hospitalized term infants." The Pediatric Infectious Disease Journal 33, no. 9 (September 2014): 920-923.  Full Text
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    • Bagai, A, Schulte, PJ, Granger, CB, Mahaffey, KW, Christenson, RH, Bell, G, Lopes, RD, Green, CL, Lincoff, AM, Armstrong, PW, and Roe, MT. "Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention." American Heart Journal 168, no. 4 (January 1, 2014): 503-511.e2.  Full Text
    • Bernardez-Pereira, S, Lopes, RD, Carrion, MJM, Santucci, EV, Soares, RM, De Oliveira Abreu, M, Laranjeira, LN, Ikeoka, DT, Zazula, AD, Moreira, FR, Cavalcanti, AB, Mesquita, ET, Peterson, ED, Califf, RM, and Berwanger, O. "Prevalence, characteristics, and predictors of early termination of cardiovascular clinical trials due to low recruitment: Insights from the ClinicalTrials.gov registry." American Heart Journal 168, no. 2 (January 1, 2014).  Full Text
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    • Diepen, SV, Reynolds, HR, Stebbins, A, Lopes, RD, Džavík, V, Ruzyllo, W, Geppert, A, Widimsky, P, Ohman, EM, Parrillo, JE, Dauerman, HL, Baran, DA, Hochman, JS, and Alexander, JH. "Incidence and outcomes associated with early heart failure pharmacotherapy in patients with ongoing cardiogenic shock." Critical Care Medicine 42, no. 2 (2014): 281-288.  Full Text
    • Goto, S, Zhu, J, Liu, L, Oh, BH, Wojdyla, DM, Aylward, P, Bahit, MC, Gersh, BJ, Hanna, M, Horowitz, J, Lopes, RD, Wallentin, L, Xavier, D, and Alexander, JH. "Efficacy and safety of apixaban compared with warfarin for stroke prevention in patients with atrial fibrillation from East Asia: A subanalysis of the apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial." American Heart Journal 168, no. 3 (January 1, 2014): 303-309.  Full Text
    • Granger, CB, Lopes, RD, Hanna, M, Ansell, J, Hylek, EM, Alexander, JH, Thomas, L, Wang, J, Bahit, MC, Verheugt, F, Lawrence, J, Xavier, D, and Wallentin, L. "Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial." American Heart Journal 169, no. 1 (January 1, 2014): 25-30.  Full Text
    • Harskamp, RE, Alexander, JH, Schulte, PJ, Jones, WS, Williams, JB, Mack, MJ, Peterson, ED, Gibson, CM, Califf, RM, Kouchoukos, NT, Ferguson, TB, De Winter, RJ, and Lopes, RD. "Impact of extracardiac vascular disease on vein graft failure and outcomes after coronary artery bypass surgery." Annals of Thoracic Surgery 97, no. 3 (2014): 824-830.
    • Harskamp, RE, Bagai, A, Halkos, ME, Rao, SV, Bachinsky, WB, Patel, MR, De Winter, RJ, Peterson, ED, Alexander, JH, and Lopes, RD. "Clinical outcomes after hybrid coronary revascularization versus coronary artery bypass surgery: A meta-analysis of 1,190 patients." American Heart Journal 167, no. 4 (January 1, 2014): 585-592.  Full Text
    • Hess, CN, Lopes, RD, Gibson, CM, Hager, R, Wojdyla, DM, Englum, BR, Mack, MJ, Califf, RM, Kouchoukos, NT, Peterson, ED, and Alexander, JH. "Saphenous vein graft failure after coronary artery bypass surgery insights from PREVENT IV." Circulation 130, no. 17 (January 1, 2014): 1445-1451.  Full Text
    • Koshizaka, M, Lopes, RD, Reyes, EM, Gibson, CM, Schulte, PJ, Hafley, GE, Hernandez, AF, Green, JB, Kouchoukos, NT, Califf, RM, Ferguson, TB, Peterson, ED, and Alexander, JH. "Long-term clinical and angiographic outcomes in patients with diabetes undergoing coronary artery bypass graft surgery: Results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV Trial." American Heart Journal 169, no. 1 (January 1, 2014): 175-184.  Full Text
    • Nelson, JA, Vavalle, JP, May, CH, Zhang, A, Newby, LK, Shaw, LK, Al-Khatib, SM, Alexander, JH, Granger, CB, and Lopes, RD. "Warfarin use and long-term outcomes in patients with acute myocardial infarction and atrial fibrillation." Journal of Thrombosis and Thrombolysis 37, no. 3 (January 1, 2014): 331-337.  Full Text
    • Testoni, D, Hayashi, M, Cohen-Wolkowiez, M, Benjamin, DK, Lopes, RD, Clark, RH, Benjamn, DK, and Smith, PB. "Late-onset bloodstream infections in hospitalized term infants." Pediatric Infectious Disease Journal 33, no. 9 (January 1, 2014): 920-923.  Full Text
    • Wallentin, L, Lopes, RD, Hanna, M, Thomas, L, Hellkamp, A, Nepal, S, Hylek, EM, Al-Khatib, SM, Alexander, JH, Alings, M, Amerena, J, Ansell, J, Aylward, P, Bartunek, J, Commerford, P, De Caterina, R, Erol, C, Harjola, V-P, Held, C, Horowitz, J, Huber, K, Husted, S, Keltai, M, Lanas, F, Lisheng, L, McMurray, JJV, Oh, B-H, Rosenqvist, M, Ruzyllo, W, Steg, PG, Vinereanu, D, Xavier, D, and Granger, CB. "Response to letter regarding article, "Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation"." Circulation 129, no. 2 (January 2014): e21-e22. (Letter)  Full Text
    • Welsh, RC, Van de Werf, F, Westerhout, CM, Goldstein, P, Gershlick, AH, Wilcox, RG, Danays, T, Bluhmki, E, Lopes, RD, Steg, PG, and Armstrong, PW. "Outcomes of a pharmacoinvasive strategy for successful versus failed fibrinolysis and primary percutaneous intervention in acute myocardial infarction (from the STrategic Reperfusion Early After Myocardial Infarction [STREAM] study)." The American journal of cardiology 114, no. 6 (January 1, 2014): 811-819.
    • Williams, JB, Peterson, ED, Wojdyla, D, Harskamp, R, Southerland, KW, Ferguson, TB, Smith, PK, Milano, CA, and Lopes, RD. "Central venous pressure after coronary artery bypass surgery: Does it predict postoperative mortality or renal failure?." Journal of Critical Care 29, no. 6 (January 1, 2014): 1006-1010.  Full Text
    • Bahit, MC, Lopes, RD, Wojdyla, DM, Hohnloser, SH, Alexander, JH, Lewis, BS, Aylward, PE, Verheugt, FWA, Keltai, M, Diaz, R, Hanna, M, Granger, CB, and Wallentin, L. "Apixaban in patients with atrial fibrillation and prior coronary artery disease: Insights from the ARISTOTLE trial." International Journal of Cardiology 170, no. 2 (December 2013): 215-220.  Full Text
    • Harskamp, RE, Zheng, Z, Alexander, JH, Williams, JB, Xian, Y, Halkos, ME, Brennan, JM, de Winter, RJ, Smith, PK, and Lopes, RD. "Status Quo of Hybrid Coronary Revascularization for Multi-Vessel Coronary Artery Disease." The Annals of Thoracic Surgery 96, no. 6 (December 2013): 2268-2277.  Full Text
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    • Bagai, A, Armstrong, PW, Stebbins, A, Mahaffey, KW, Hochman, JS, Weaver, WD, Patel, MR, Granger, CB, and Lopes, RD. "Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study." American Heart Journal 166, no. 5 (November 1, 2013): 913-919.  Full Text
    • Fosbol, EL, Wang, TY, Li, S, Piccini, J, Lopes, RD, Mills, RM, Klaskala, W, Thomas, L, Roe, MT, and Peterson, ED. "Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy." American Heart Journal 166, no. 5 (November 2013): 864-870.  Full Text
    • Fosbol, EL, Wang, TY, Li, S, Piccini, J, Lopes, RD, Mills, RM, Klaskala, W, Thomas, L, Roe, MT, and Peterson, ED. "Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy." American Heart Journal 166, no. 5 (November 1, 2013): 864-870.  Full Text
    • Parashar, S, Kella, D, Reid, KJ, Spertus, JA, Tang, F, Langberg, J, Vaccarino, V, Kontos, MC, Lopes, RD, and Lloyd, MS. "New-onset atrial fibrillation after acute myocardial infarction and its relation to admission biomarkers (from the TRIUMPH registry)." The American Journal of Cardiology 112, no. 9 (November 2013): 1390-1395.  Full Text
    • Williams, JB, Lopes, RD, Hafley, GE, Bruce Ferguson, T, Mack, MJ, Michael Gibson, C, Harrington, RA, Peterson, ED, Smith, PK, Mehta, RH, and Alexander, JH. "Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting." Journal of Thrombosis and Thrombolysis 36, no. 4 (November 1, 2013): 384-393.  Full Text
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    • Schmidt, MM, Lopes, RD, Newby, LK, Moura, MR, Stochero, L, Gottschall, CM, and Quadros, AS. "Anger control and cardiovascular outcomes." International Journal of Cardiology 168, no. 4 (October 9, 2013): 4338-4339. (Letter)  Full Text
    • Lopes, RD, White, JA, Atar, D, Keltai, M, Kleiman, NS, White, HD, Widimsky, P, Zeymer, U, Giugliano, RP, Tricoci, P, Braunwald, E, Bode, C, Ohman, EM, Armstrong, PW, and Newby, LK. "Incidence, treatment, and outcomes of atrial fibrillation complicating non-ST-segment elevation acute coronary syndromes." Int J Cardiol 168, no. 3 (October 3, 2013): 2510-2517.  Full Text  Link to Item
    • Giraldez, RR, Lopes, RD, and Newby, LK. "Responding to the letter to the editor by Saver." Am Heart J 166, no. 4 (October 2013): e39-. (Letter)  Full Text  Link to Item
    • Sposato, LA, Coppola, ML, Altamirano, J, Borrego Guerrero, B, Casanova, J, De Martino, M, Díaz, A, Feigin, VL, Funaro, F, Gradillone, ME, Lewin, ML, Lopes, RD, López, DH, Louge, M, Maccarone, P, Martens, C, Miguel, M, Rabinstein, A, Morasso, H, Riccio, PM, Saposnik, G, Silva, D, Suasnabar, R, Truelsen, T, Uzcudun, A, Viviani, CA, and Bahit, MC. "Program for the epidemiological evaluation of stroke in Tandil, Argentina (PREVISTA) study: Rationale and design." International Journal of Stroke 8, no. 7 (October 1, 2013): 591-597.  Full Text
    • van Diepen, S, Newby, LK, Lopes, RD, Stebbins, A, Hasselblad, V, James, S, Roe, MT, Ezekowitz, JA, Moliterno, DJ, Neumann, F-J, Reist, C, Mahaffey, KW, Hochman, JS, Hamm, CW, Armstrong, PW, Granger, CB, Theroux, P, and APEX AMI Investigators, . "Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: an APEX AMI substudy." International Journal of Cardiology 168, no. 3 (October 2013): 2127-2133.  Full Text
    • Hess, CN, Al-Khatib, SM, Granger, CB, and Lopes, R. "A review of apixaban for stroke prevention in atrial fibrillation: insights from ARISTOTLE." Expert Rev Cardiovasc Ther 11, no. 9 (September 2013): 1105-1114. (Review)  Full Text  Link to Item
    • Lopes, RD, White, JA, Tricoci, P, White, HD, Armstrong, PW, Braunwald, E, Giugliano, RP, Harrington, RA, Lewis, BS, Brogan, GX, Gibson, CM, Califf, RM, and Newby, LK. "Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: insights from the EARLY ACS trial." International Journal of Cardiology 167, no. 6 (September 2013): 2580-2587.  Full Text
    • Lorga Filho, AM, Azmus, AD, Soeiro, AM, Quadros, AS, Avezum, A, Marques, AC, Franci, A, Manica, ALL, Volschan, A, De Paola, AAV, Greco, AIL, Ferreira, ACN, Sousa, ACS, Pesaro, AEP, Simão, AF, Lopes, ASSA, Timerman, A, Ramos, AIO, Alves, BR, Caramelli, B, Mendes, BA, Polanczyk, CA, Montenegro, CEL, Barbosa, CJDG, Serrano, CV, Melo, CCL, Pinho, C, Moreira, DAR, Calderaro, D, Gualandro, DM, Armaganijan, D, Machado Neto, EA, Bocchi, EA, Paiva, EF, Stefanini, E, D'Amico, E, Evaristo, EF, Silva, EER, Fernandes, F, Brito, FS, Bacal, F, Ganem, F, Gomes, FLT, Mattos, FR, Moraes Neto, FR, Tarasoutchi, F, Darrieux, FCC, Feitosa, GS, Fenelon, G, Morais, GR, Correa Filho, H, Castro, I, Gonçalves, I, Atié, J, Souza Neto, JD, Ferreira, JFM, Nicolau, JC, Faria Neto, JR, Annichino-Bizzacchi, JM, Zimerman, LI, Piegas, LS, Pires, LJT, Baracioli, LM, Silva, LB, Mattos, LAP, Lisboa, LAF, Magalhães, LPM, Lopes, MACQ, Montera, MW, Figueiredo, MJO, Malachias, MVB, Gaz, MVB, Andrade, MD, Bacellar, MSC, Barbosa, MR, Clausell, NO, Dutra, OP, Coelho, OR, Yu, PC, Lavítola, PL, Lemos Neto, PA, Andrade, PB, Farsky, PS, Franco, RA, Kalil, RAK, Lopes, RD, Esporcatte, R, Heinisch, RH, Kalil Filho, R, Giraldez, RRCV, Alves, RC, Leite, REGS, Gagliardi, RJ, Ramos, RF, Montenegro, ST, Accorsi, TAD, Jardim, TSV, Scudeler, TL, Moisés, VA, and Portal, VL. "[Brazilian guidelines on platelet antiaggregants and anticoagulants in cardiology]." Arquivos Brasileiros De Cardiologia 101, no. 3 Suppl 3 (September 2013): 1-95.  Full Text
    • Al-Khatib, SM, Thomas, L, Wallentin, L, Lopes, RD, Gersh, B, Garcia, D, Ezekowitz, J, Alings, M, Yang, H, Alexander, JH, Flaker, G, Hanna, M, and Granger, CB. "Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial." European Heart Journal 34, no. 31 (August 2013): 2464-2471.  Full Text
    • Gonzalez, MM, Timerman, S, Gianotto-Oliveira, R, Polastri, TF, Canesin, MF, Schimidt, A, Siqueira, AW, Pispico, A, Longo, A, Pieri, A, Reis, A, Tanaka, ACS, Santos, AM, Quilici, AP, Ribeiro, ACL, Barreto, ACP, Pazin-Filho, A, Timerman, A, Machado, CA, Franchin Neto, C, Miranda, CH, Medeiros, CR, Malaque, CMS, Bernoche, C, Gonçalves, DM, Sant'Ana, DG, Osawa, EA, Peixoto, E, Arfelli, E, Evaristo, EF, Azeka, E, Gomes, EP, Wen, FH, Ferreira, FG, Lima, FG, Mattos, FR, Galas, FG, and Marques, FRB et al. "[First guidelines of the Brazilian Society of Cardiology on Cardiopulmonary Resuscitation and Cardiovascular Emergency Care]." Arquivos brasileiros de cardiologia 101, no. 2 Suppl 3 (August 2013): 1-221.  Full Text
    • Koshizaka, M, Lopes, RD, Newby, LK, Schulte, PJ, Clare, RM, Tricoci, P, Mahaffey, KW, Ogawa, H, Harrington, RA, and Alexander, JH. "Relationship between diabetes, race, obesity and outcomes in patients with acute coronary syndrome: a pool analysis from randomized trials." EUROPEAN HEART JOURNAL 34 (August 2013): 787-787.  Link to Item
    • Mahaffey, KW, Hafley, G, Dickerson, S, Burns, S, Tourt-Uhlig, S, White, J, Newby, LK, Komajda, M, McMurray, J, Bigelow, R, Home, PD, and Lopes, RD. "Results of a reevaluation of cardiovascular outcomes in the RECORD trial." American Heart Journal 166, no. 2 (August 2013): 240-249.e1.  Full Text
    • Steinberg, BA, Kim, S, Piccini, JP, Fonarow, GC, Lopes, RD, Thomas, L, Ezekowitz, MD, Ansell, J, Kowey, P, Singer, DE, Gersh, B, Mahaffey, KW, Hylek, E, Go, AS, Chang, P, Peterson, ED, and ORBIT-AF Investigators and Patients, . "Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry." Circulation 128, no. 7 (August 2013): 721-728.  Full Text
    • Cullen, MW, Kim, S, Piccini, JP, Ansell, JE, Fonarow, GC, Hylek, EM, Singer, DE, Mahaffey, KW, Kowey, PR, Thomas, L, Go, AS, Lopes, RD, Chang, P, Peterson, ED, Gersh, BJ, and ORBIT-AF Investigators, . "Risks and benefits of anticoagulation in atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry." Circulation. Cardiovascular Quality and Outcomes 6, no. 4 (July 2013): 461-469.  Full Text
    • Lopes, RD, Becker, RC, Newby, LK, Peterson, ED, Hylek, EM, Giugliano, R, Granger, CB, Mahaffey, KW, Carvalho, AC, Berwanger, O, Giraldez, RR, Feitosa-Filho, GS, Barbosa, MM, da Consolacao V Moreira, M, Kalil, RAK, Freitas, M, de Campos Guerra, JC, Barros, MVL, da Rocha Rodrigues, T, Lopes, AC, and Garcia, DA. "Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), October 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil." J Thromb Thrombolysis 36, no. 1 (July 2013): 115-130.  Full Text  Link to Item
    • de Souza Brito, F, Lopes, RD, and Alexander, JH. "The safety and efficacy of apixaban : where do we stand in 2013?." Expert Opin Drug Saf 12, no. 4 (July 2013): 559-567. (Review)  Full Text  Link to Item
    • Hijazi, Z, Wallentin, L, Siegbahn, A, Andersson, U, Christersson, C, Ezekowitz, J, Gersh, BJ, Hanna, M, Hohnloser, S, Horowitz, J, Huber, K, Hylek, EM, Lopes, RD, McMurray, JJV, and Granger, CB. "N-terminal pro-B-type natriuretic peptide for risk assessment in patients with atrial fibrillation: insights from the ARISTOTLE Trial (Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation)." Journal of the American College of Cardiology 61, no. 22 (June 2013): 2274-2284.  Full Text
    • Leonardi, S, Stebbins, A, Lopes, RD, Lokhnygina, Y, Todd, M, Bhatt, DL, Stone, GW, Lincoff, AM, Dauerman, HL, Gibson, CM, White, HD, Parikh, KH, Gruberg, L, Herrmann, HC, McLaurin, BT, Goodman, SG, and Mahaffey, KW. "Quantification of the effect of clopidogrel on enzymatic infarct size related to a percutaneous coronary intervention in patients with acute coronary syndromes: insights from the CHAMPION percutaneous coronary intervention trial." Coronary Artery Disease 24, no. 4 (June 2013): 321-327.  Full Text
    • Wallentin, L, Lopes, RD, Hanna, M, Thomas, L, Hellkamp, A, Nepal, S, Hylek, EM, Al-Khatib, SM, Alexander, JH, Alings, M, Amerena, J, Ansell, J, Aylward, P, Bartunek, J, Commerford, P, De Caterina, R, Erol, C, Harjola, V-P, Held, C, Horowitz, JD, Huber, K, Husted, S, Keltai, M, Lanas, F, Lisheng, L, McMurray, JJV, Oh, B-H, Rosenqvist, M, Ruzyllo, W, Steg, PG, Vinereanu, D, Xavier, D, Granger, CB, and Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Investigators, . "Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation." Circulation 127, no. 22 (June 2013): 2166-2176.  Full Text
    • Harskamp, RE, Lopes, RD, Baisden, CE, de Winter, RJ, and Alexander, JH. "Saphenous vein graft failure after coronary artery bypass surgery: pathophysiology, management, and future directions." Annals of Surgery 257, no. 5 (May 2013): 824-833. (Review)  Full Text
    • Harskamp, RE, Williams, JB, Hill, RC, de Winter, RJ, Alexander, JH, and Lopes, RD. "Saphenous vein graft failure and clinical outcomes: toward a surrogate end point in patients following coronary artery bypass surgery?." American Heart Journal 165, no. 5 (May 2013): 639-643.  Full Text
    • Lopes, RD, Granger, CB, and Alexander, KP. "The reply." Am J Med 126, no. 5 (May 2013): e21-. (Letter)  Full Text  Link to Item
    • McMurray, JJV, Ezekowitz, JA, Lewis, BS, Gersh, BJ, van Diepen, S, Amerena, J, Bartunek, J, Commerford, P, Oh, B-H, Harjola, V-P, Al-Khatib, SM, Hanna, M, Alexander, JH, Lopes, RD, Wojdyla, DM, Wallentin, L, Granger, CB, and ARISTOTLE Committees and Investigators, . "Left ventricular systolic dysfunction, heart failure, and the risk of stroke and systemic embolism in patients with atrial fibrillation: insights from the ARISTOTLE trial." Circulation. Heart Failure 6, no. 3 (May 2013): 451-460.  Full Text
    • Guptill, JT, Mehta, RH, Armstrong, PW, Horton, J, Laskowitz, D, James, S, Granger, CB, and Lopes, RD. "Stroke after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction: timing, characteristics, and clinical outcomes." Circulation. Cardiovascular Interventions 6, no. 2 (April 2, 2013): 176-183.  Full Text
    • Rose, JJ, Newby, LK, Broderick, S, Chiswell, K, Van de Werf, F, Armstrong, PW, Mahaffey, KW, Harrington, RA, Ohman, EM, Giugliano, RP, Goodman, SG, White, HD, Califf, RM, Granger, CB, and Lopes, RD. "Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes." Journal of the American College of Cardiology 61, no. 13 (April 2013): 1461-1463. (Letter)  Full Text
    • Berwanger, O, Piva e Mattos, LA, Martin, JFV, Lopes, RD, Figueiredo, EL, Magnoni, D, Precoma, DB, Machado, CA, Guimarães, JI, and Andrade, JPD. "Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study." Arquivos brasileiros de cardiologia 100, no. 3 (March 2013): 212-220.  Full Text
    • Staico, R, Armaganijan, L, Dietrich, C, Abizaid, A, Moreira, D, Lopes, R, Almeida, J, and Franco, M. "Renal sympathetic ablation using an irrigated-tip catheter: An attractive option?." Revista Brasileira de Cardiologia Invasiva 21, no. 1 (March 1, 2013).
    • Truffa, AA, Lopes, RD, and Newby, LK. "Alternatives to warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a look back at the state of the field in 2012." Postgrad Med 125, no. 2 (March 2013): 146-157. (Review)  Full Text  Link to Item
    • Lopes, RD, Al-Khatib, SM, and Wallentin, L. "Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial (vol 380, pg 1749, 2012)." LANCET 381, no. 9862 (January 19, 2013): 204-204.  Link to Item
    • Harskamp, RE, Beijk, MA, Damman, P, Tijssen, JG, Lopes, RD, and de Winter, RJ. "Prehospitalization antiplatelet therapy and outcomes after saphenous vein graft intervention." Am J Cardiol 111, no. 2 (January 15, 2013): 153-158.  Full Text  Link to Item
    • Azevedo, REU, Lopes, RD, Canziani, MEF, Gonçalves, I, Campos, PCGD, Vieira, MLC, Stefanini, E, and Carvalho, AC. "Mortality after myocardial infarction: The role of renal function and systolic and diastolic functions of the left ventricle." Journal of Nephrology 26, no. 6 (January 1, 2013): 1089-1096.  Full Text
    • Bahit, MC, Lopes, RD, Clare, RM, Newby, LK, Pieper, KS, Werf, FVD, Armstrong, PW, Mahaffey, KW, Harrington, RA, Diaz, R, Ohman, EM, White, HD, James, S, and Granger, CB. "Heart failure complicating non-st-segment elevation acute coronary syndrome: Timing, predictors, and clinical outcomes." JACC: Heart Failure 1, no. 3 (2013): 223-229.  Full Text
    • Bahit, MC, Lopes, RD, Wojdyla, DM, Hohnloser, SH, Alexander, JH, Lewis, BS, Aylward, PE, Verheugt, FWA, Keltai, M, Diaz, R, Hanna, M, Granger, CB, and Wallentin, L. "Apixaban in patients with atrial fibrillation and prior coronary artery disease: Insights from the ARISTOTLE trial." International Journal of Cardiology (2013).
    • Diepen, SV, Newby, LK, Lopes, RD, Stebbins, A, Hasselblad, V, James, S, Roe, MT, Ezekowitz, JA, Moliterno, DJ, Neumann, F-J, and al, E. "Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: An APEX AMI substudy." International Journal of Cardiology 168, no. 3 (2013): 2127-2133.  Full Text
    • Garcia, DA, Wallentin, L, Lopes, RD, Thomas, L, Alexander, JH, Hylek, EM, Ansell, J, Hanna, M, Lanas, F, Flaker, G, Commerford, P, Xavier, D, Vinereanu, D, Yang, H, and Granger, CB. "Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: Results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial." American Heart Journal 166, no. 3 (2013): 549-558.  Full Text
    • Garcia, DA, Wallentin, L, Lopes, RD, Thomas, L, Alexander, JH, Hylek, EM, Ansell, J, Hanna, M, Lanas, F, Flaker, G, and al, E. "Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: Results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial." American Heart Journal (2013).  Full Text
    • Giraldez, RR, Clare, RM, Lopes, RD, Dalby, AJ, Prabhakaran, D, Brogan, GX, Giugliano, RP, James, SK, Tanguay, J-F, Pollack, CV, Harrington, RA, Braunwald, E, and Newby, LK. "Prevalence and clinical outcomes of undiagnosed diabetes mellitus and prediabetes among patients with high-risk non-st-segment elevation acute coronary syndrome." American Heart Journal 165, no. 6 (2013): 918-925.e2.  Full Text
    • Giraldez, RR, Clare, RM, Lopes, RD, Dalby, AJ, Prabhakaran, D, Jr, GXB, Giugliano, RP, James, SK, Tanguay, J-F, Jr, CVP, and al, E. "Prevalence and clinical outcomes of undiagnosed diabetes mellitus and prediabetes among patients with high-risk non-ST-segment elevation acute coronary syndrome." American Heart Journal (2013).  Full Text
    • Gonzalez, MMC, Timerman, S, Gianotto-Oliveira, R, Polastri, TF, Canesin, MF, Schimidt, A, Siqueira, AW, Pispico, A, Longo, A, Pieri, A, Reis, A, Tanaka, ACS, Santos, AM, Quilici, AP, Ribeiro, ACL, Barreto, ACP, Pazin-Filho, A, Timerman, A, Machado, CA, Neto, CF, Miranda, CH, Medeiros, CR, Malaque, CMS, Bernoche, C, Gonçalves, DM, Sant'Ana, DG, Osawa, EA, Peixoto, E, Arfelli, E, Evaristo, EF, Azeka, E, Gomes, EP, Wen, FH, Ferreira, FG, Lima, FG, Mattos, FR, Galas, FG, and Marques, FRB et al. "I guidelines for cardiopulmonary resuscitation and emergency cardiovascular care society of cardiology." Arquivos Brasileiros de Cardiologia 101, no. 2 SUPPL.3 (2013): 3-221.  Full Text
    • Harskamp, RE, Williams, JB, Hill, RC, Winter, RJD, Alexander, JH, and Lopes, RD. "Saphenous vein graft failure and clinical outcomes: Toward a surrogate end point in patients following coronary artery bypass surgery?." American Heart Journal 165, no. 5 (2013): 639-643.  Full Text
    • Lauzier, F, Arnold, DM, Rabbat, C, Heels-Ansdell, D, Zarychanski, R, Dodek, P, Ashley, BJ, Albert, M, Khwaja, K, Ostermann, M, Skrobik, Y, Fowler, R, McIntyre, L, Nates, JL, Karachi, T, Lopes, RD, Zytaruk, N, Finfer, S, Crowther, M, and Cook, D. "Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis." Intensive Care Medicine (2013): 1-9.
    • Leonardi, S, Stebbins, A, Lopes, RD, Lokhnygina, Y, Todd, M, Bhatt, DL, Stone, GW, Lincoff, AM, Dauerman, HL, Gibson, CM, White, HD, Parikh, KH, Gruberg, L, Herrmann, HC, McLaurin, BT, Goodman, SG, and Mahaffey, KW. "Quantification of the effect of clopidogrel on enzymatic infarct size related to a percutaneous coronary intervention in patients with acute coronary syndromes: Insights from the CHAMPION percutaneous coronary intervention trial." Coronary Artery Disease 24, no. 4 (2013): 321-327.  Full Text
    • Lopes, RD, Al-Khatib, SM, and Wallentin, L. "Erratum: Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fi brillation: A secondary analysis of a randomised controlled trial (The Lancet (2012) 380 (1749-58))." The Lancet 381, no. 9862 (January 1, 2013): 204-.
    • Lopes, RD, Becker, RC, Newby, LK, Peterson, ED, Hylek, EM, Giugliano, R, Granger, CB, Mahaffey, KW, Carvalho, AC, Berwanger, O, Giraldez, RR, Feitosa-Filho, GS, Barbosa, MM, Moreira, MDCV, Kalil, RAK, Freitas, M, Guerra, JCDC, Barros, MVL, Rodrigues, TDR, Lopes, AC, and Garcia, DA. "Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), october 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil." Journal of Thrombosis and Thrombolysis 36, no. 1 (2013): 115-130.  Full Text
    • Lopes, RD, Dickerson, S, Hafley, G, Burns, S, Tourt-Uhlig, S, White, J, Newby, LK, Komajda, M, McMurray, J, Bigelow, R, Home, PD, and Mahaffey, KW. "Methodology of a reevaluation of cardiovascular outcomes in the RECORD trial: Study design and conduct." American Heart Journal 166, no. 2 (2013): 208-216.e28.  Full Text
    • Lopes, RD, Dickerson, S, Hafley, G, Burns, S, Tourt-Uhlig, S, White, J, Newby, LK, Komajda, M, McMurray, J, Bigelow, R, and al, E. "Methodology of a reevaluation of cardiovascular outcomes in the RECORD trial: Study design and conduct." American Heart Journal (2013).  Full Text
    • Lopes, RD, Lokhnygina, Y, Hasselblad, V, Newby, KL, Yow, E, Granger, CB, Armstrong, PW, Hochman, JS, Mills, JS, Ruzyllo, W, and Mahaffey, KW. "Methods of creatine kinase-MB analysis to predict mortality in patients with myocardial infarction treated with reperfusion therapy." Trials 14 (January 2013): 123-null.  Full Text  Open Access Copy
    • Lopes, RD, White, JA, Atar, D, Keltai, M, Kleiman, NS, White, HD, Widimsky, P, Zeymer, U, Giugliano, RP, Tricoci, P, and al, E. "Incidence, treatment, and outcomes of atrial fibrillation complicating non-ST-segment elevation acute coronary syndromes." International Journal of Cardiology 168, no. 3 (2013): 2510-2517.  Full Text
    • Lopes, RD, White, JA, Tricoci, P, White, HD, Armstrong, PW, Braunwald, E, Giugliano, RP, Harrington, RA, Lewis, BS, Jr, GXB, Gibson, CM, Califf, RM, and Newby, LK. "Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: Insights from the EARLY ACS trial." International Journal of Cardiology 167, no. 6 (2013): 2580-2587.  Full Text
    • Lorga Filho, AM, Azmus, A, Soeiro, A, Quadros, A, Avezum Junior, A, Marques, A, Franci, A, Manica, A, Volschan, A, De Paola, A, Greco, A, ACN, F, Sousa, A, Pesaro, A, Simão, A, Lopes, A, Timerman, A, Ramos, A, Alves, B, Caramelli, B, Mendes, B, Polanczyk, C, Montenegro, C, Barbosa, C, Serrano Junior, C, Melo, C, Pinho, C, Moreira, D, Calderaro, D, Gualandro, D, Armaganijan, D, Machado Neto, E, Bocchi, E, Paiva, E, Stefanini, E, D’Amico, E, Evaristo, E, Silva, E, Fernandes, F, and Brito Junior, F et al. "Diretrizes Brasileiras de Antiagregantes Plaquetários e Anticoagulantes em Cardiologia." Arquivos Brasileiros de Cardiologia 101, no. 3 (2013): 01-93.  Full Text
    • Mahaffey, KW, Hafley, G, Dickerson, S, Burns, S, Tourt-Uhlig, S, White, J, Newby, LK, Komajda, M, McMurray, J, Bigelow, R, Home, PD, and Lopes, RD. "Results of a reevaluation of cardiovascular outcomes in the RECORD trial." American Heart Journal 166, no. 2 (2013): 240-249.e1.  Full Text
    • Nicolau, JC, Corbalan, R, Diaz, R, Bahit, C, Armstrong, PW, Granger, CB, and Lopes, RD. "Cardiovascular clinical research in South America." American Heart Journal (2013).  Full Text
    • Nicolau, JC, Corbalan, R, Diaz, R, Bahit, C, Armstrong, PW, Granger, CB, and Lopes, RD. "Cardiovascular clinical research in South America." American Heart Journal 165, no. 6 (2013): 848-853.  Full Text
    • Ritt, LE, Carvalho, AC, Feitosa, GS, Pinho-Filho, JA, Andrade, MVS, Feitosa-Filho, GS, Newby, LK, and Lopes, RD. "Cardiopulmonary exercise and 6-min walk tests as predictors of quality of life and long-term mortality among patients with heart failure due to Chagas disease." International Journal of Cardiology (2013).  Full Text
    • Schmidt, MM, Lopes, RD, Newby, LK, Moura, MR, Stochero, L, Gottschall, CM, and Quadros, AS. "Anger control and cardiovascular outcomes." International Journal of Cardiology (2013).  Full Text
    • Leonardi, S, Thomas, L, Neely, ML, Tricoci, P, Lopes, RD, White, HD, Armstrong, PW, Giugliano, RP, Antman, EM, Califf, RM, Newby, LK, and Mahaffey, KW. "Comparison of the prognosis of spontaneous and percutaneous coronary intervention-related myocardial infarction." Journal of the American College of Cardiology 60, no. 22 (December 2012): 2296-2304.  Full Text
    • Cecilia Bahit, M, Lopes, RD, Hohnloser, SH, Wojdyla, D, Alexander, JH, Lewis, BS, Aylward, P, Verheugt, FW, Keltai, M, Diaz, R, Mohan, P, Granger, CB, and Wallentin, L. "Apixaban in Patients with Atrial Fibrillation and Prior Coronary Artery Disease: Insights from the ARISTOTLE Trial." CIRCULATION 126, no. 21 (November 20, 2012).  Link to Item
    • Garcia, DA, Alexander, JH, Lopes, RD, Thomas, L, Yang, H, Ansell, I, Commerford, P, Flaker, G, Lanas, F, Mohan, P, Vinereanu, D, Xavier, D, Granger, C, and Wallentin, L. "Apixaban versus warfarin in Patients with Atrial Fibrillation in relation to Prior Warfarin Use: Insights from the ARISTOTLE trial." CIRCULATION 126, no. 21 (November 20, 2012).  Link to Item
    • Hylek, EM, Held, C, Alexander, JH, Lopes, RD, DeCaterina, R, Huber, K, Jansky, P, Steg, G, Hanna, M, Wallentin, L, and Granger, C. "Reduction in Bleeding with Apixaban versus Warfarin is Consistent Across Subgroups and Locations: Insights from the ARISTOTLE Trial." Circulation 126, no. 21 (November 20, 2012).  Link to Item
    • Lopes, RD, Al-Khatib, SM, Wallentin, L, Yang, H, Ansell, J, Bahit, MC, De Caterina, R, Dorian, P, Easton, JD, Erol, C, Ezekowitz, JA, Gersh, BJ, Granger, CB, Hohnloser, SH, Horowitz, J, Hylek, EM, McMurray, JJV, Mohan, P, Vinereanu, D, and Alexander, JH. "Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial." Lancet 380, no. 9855 (November 17, 2012): 1749-1758.  Full Text  Link to Item
    • "Rao SV, Dai D, Subherwal S, Weintraub WS, Brindis RS, Messenger JC, Lopes RD, Peterson ED. Association Between Periprocedural Bleeding and Long-Term Outcomes Following Percutaneous Coronary Intervention in Older Patients. J Am Coll Cardiol Intv 2012;5:958–65." JACC: Cardiovascular Interventions 5, no. 11 (November 2012): 1192-1192.  Full Text
    • Hess, CN, Becker, RC, Alexander, JH, and Lopes, RD. "Antithrombotic therapy in heparin-induced thrombocytopenia: guidelines translated for the clinician." J Thromb Thrombolysis 34, no. 4 (November 2012): 552-561. (Review)  Full Text  Link to Item
    • Hohnloser, SH, Hijazi, Z, Thomas, L, Alexander, JH, Amerena, J, Hanna, M, Keltai, M, Lanas, F, Lopes, RD, Lopez-Sendon, J, Granger, CB, and Wallentin, L. "Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial." European Heart Journal 33, no. 22 (November 2012): 2821-2830.  Full Text
    • Vavalle, JP, Lopes, RD, Chen, AY, Newby, LK, Wang, TY, Shah, BR, Ho, PM, Wiviott, SD, Peterson, ED, Roe, MT, and Granger, CB. "Hospital length of stay in patients with non-ST-segment elevation myocardial infarction." Am J Med 125, no. 11 (November 2012): 1085-1094.  Full Text  Link to Item
    • Eapen, ZJ, Al-Khatib, S, Lopes, RD, Wang, Y, Bao, H, Curtis, J, Heidenreich, PA, Hernandez, AF, Peterson, ED, and Hammill, SC. "Are racial/ethnic gaps in the use of cardiac resynchronization therapy narrowing?: an analysis of 107,096 patients from the National Cardiovascular Data Registry's ICD Registry." Journal of the American College of Cardiology 60, no. 16 (October 2012): 1577-1578. (Letter)  Full Text
    • Hess, CN, Broderick, S, Piccini, JP, Alexander, KP, Newby, LK, Shaw, LK, Mahaffey, KW, Alexander, JH, Peterson, ED, Granger, CB, and Lopes, RD. "Antithrombotic therapy for atrial fibrillation and coronary artery disease in older patients." Am Heart J 164, no. 4 (October 2012): 607-615.  Full Text  Link to Item
    • Quadros, AS, Cambruzzi, E, Sebben, J, David, RB, Abelin, A, Welter, D, Sarmento-Leite, R, Mehta, RH, Gottschall, CA, and Lopes, RD. "Red versus white thrombi in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: clinical and angiographic outcomes." AMERICAN HEART JOURNAL 164, no. 4 (October 2012): 553-560.  Full Text  Link to Item
    • Staico, R, Armaganijan, L, and Lopes, RD. "Coronary embolism and calcified aortic valve: is there a correlation?." JOURNAL OF THROMBOSIS AND THROMBOLYSIS 34, no. 3 (October 2012): 425-427.  Full Text  Link to Item
    • Lopes, RD, Li, L, Granger, CB, Wang, TY, Foody, JM, Funk, M, Peterson, ED, and Alexander, KP. "Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes." Am J Med 125, no. 9 (September 2012): 897-905.  Full Text  Link to Item
    • Lopes, RD, Williams, JB, Mehta, RH, Reyes, EM, Hafley, GE, Allen, KB, Mack, MJ, Peterson, ED, Harrington, RA, Gibson, CM, Califf, RM, Kouchoukos, NT, Ferguson, TB, Lorenz, TJ, and Alexander, JH. "Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results." American Heart Journal 164, no. 3 (September 2012): 379-386.e1.  Full Text
    • Pesaro, AEP, Serrano, CV, Katz, M, Campos, AH, Lopes, RD, Marti, LC, Martins, HS, Sunahara, RS, Maranhão, RC, and Nicolau, JC. "Inflammation and circulating endothelial progenitor cells in patients with coronary artery disease and residual platelet reactivity." Clinics (Sao Paulo, Brazil) 67, no. 9 (September 2012): 1117-1121.  Full Text
    • Rao, SV, Dai, D, Subherwal, S, Weintraub, WS, Brindis, RS, Messenger, JC, Lopes, RD, and Peterson, ED. "Association between periprocedural bleeding and long-term outcomes following percutaneous coronary intervention in older patients." JACC Cardiovasc Interv 5, no. 9 (September 2012): 958-965.  Full Text  Link to Item
    • van Diepen, S, Newby, L, Lopes, R, Stebbins, A, Hasselblad, V, James, S, Roe, M, Ezekowitz, J, Moliterno, D, Neumann, F, Reist, C, Hochman, J, Mahaffey, K, Hamm, C, Armstrong, P, Granger, C, and Theroux, P. "726 Acute Phase Inflammatory Biomarkers Add Little Predictive Value to Clinical Factors Plus NT-proBNP Among Patients With ST-Segment Elevation Myocardial Infarction: An Apex AMI Trial Substudy." Canadian Journal of Cardiology 28, no. 5 (September 2012): S378-S378.  Full Text
    • Lopes, RD, Subherwal, S, Holmes, DN, Thomas, L, Wang, TY, Rao, SV, Magnus Ohman, E, Roe, MT, Peterson, ED, and Alexander, KP. "The association of in-hospital major bleeding with short-, intermediate-, and long-term mortality among older patients with non-ST-segment elevation myocardial infarction." Eur Heart J 33, no. 16 (August 2012): 2044-2053.  Full Text  Link to Item
    • Williams, JB, Peterson, ED, Brennan, JM, Sedrakyan, A, Tavris, D, Alexander, JH, Lopes, RD, Dokholyan, RS, Zhao, Y, O'Brien, SM, Michler, RE, Thourani, VH, Edwards, FH, Duggirala, H, Gross, T, Marinac-Dabic, D, and Smith, PK. "Association between endoscopic vs open vein-graft harvesting and mortality, wound complications, and cardiovascular events in patients undergoing CABG surgery." JAMA 308, no. 5 (August 2012): 475-484.  Full Text
    • Lopes, RD, Becker, RC, Newby, LK, Peterson, ED, Hylek, EM, Granger, CB, Crowther, M, Wang, T, Carvalho, AC, Berwanger, O, Giraldez, RR, Feitosa, GS, Ribeiro, JP, Darze, E, Kalil, RAK, Andrande, M, Boas, FV, Andrade, J, Rocha, AT, Harrington, RA, Lopes, AC, and Garcia, DA. "Highlights from the IV International Symposium of Thrombosis and Anticoagulation (ISTA), October 20-21, 2011, Salvador, Bahia, Brazil." J Thromb Thrombolysis 34, no. 1 (July 2012): 143-163.  Full Text  Link to Item
    • Truffa, AAM, Granger, CB, White, KR, Newby, LK, Mehta, RH, Hochman, JS, Patel, MR, Pieper, KS, Al-Khalidi, HR, Armstrong, PW, and Lopes, RD. "Serious infection after acute myocardial infarction: incidence, clinical features, and outcomes." JACC Cardiovasc Interv 5, no. 7 (July 2012): 769-776.  Full Text  Link to Item
    • van Diepen, S, Roe, MT, Lopes, RD, Stebbins, A, James, S, Newby, LK, Moliterno, DJ, Neumann, F-J, Ezekowitz, JA, Mahaffey, KW, Hochman, JS, Hamm, CW, Armstrong, PW, Theroux, P, and Granger, CB. "Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial." J Thromb Thrombolysis 34, no. 1 (July 2012): 106-113.  Full Text  Link to Item
    • van Diepen, S, Widimsky, P, Lopes, RD, White, KR, Weaver, WD, Van de Werf, F, Ardissino, D, van't Hof, AWJ, Armstrong, PW, and Granger, CB. "Transfer times and outcomes in patients with ST-segment-elevation myocardial infarction undergoing interhospital transfer for primary percutaneous coronary intervention: APEX-AMI insights." Circ Cardiovasc Qual Outcomes 5, no. 4 (July 1, 2012): 437-444.  Full Text  Link to Item
    • Easton, JD, Lopes, RD, Bahit, MC, Wojdyla, DM, Granger, CB, Wallentin, L, Alings, M, Goto, S, Lewis, BS, Rosenqvist, M, Hanna, M, Mohan, P, Alexander, JH, Diener, H-C, and ARISTOTLE Committees and Investigators, . "Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial." The Lancet. Neurology 11, no. 6 (June 2012): 503-511.  Full Text
    • James, SK, Storey, RF, Khurmi, NS, Husted, S, Keltai, M, Mahaffey, KW, Maya, J, Morais, J, Lopes, RD, Nicolau, JC, Pais, P, Raev, D, Lopez-Sendon, JL, Stevens, SR, Becker, RC, and PLATO Study Group, . "Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack." Circulation 125, no. 23 (June 2012): 2914-2921.  Full Text
    • Ritt, LE, Carvalho, AC, Feitosa, GS, Pinho-Filho, JA, MacEdo, CRB, Vilas-Boas, F, Andrade, MVS, Feitosa-Filho, GS, Almeida, AJG, Barojas, M, and Lopes, RD. "Heart failure survival score in patients with chagas disease: Correlation with functional variables." Revista Espanola de Cardiologia 65, no. 6 (June 1, 2012): 538-543. (Review)  Full Text
    • Ritt, LE, Carvalho, AC, Feitosa, GS, Pinho-Filho, JA, Macedo, CRB, Vilas-Boas, F, Andrade, MVS, Feitosa-Filho, GS, Almeida, AJG, Barojas, M, and Lopes, RD. "Heart Failure Survival Score in Patients With Chagas Disease: Correlation With Functional Variables." REVISTA ESPANOLA DE CARDIOLOGIA 65, no. 6 (June 2012): 538-543.  Full Text  Link to Item
    • Berwanger, O, Guimarães, HP, Laranjeira, LN, Cavalcanti, AB, Kodama, AA, Zazula, AD, Santucci, EV, Victor, E, Tenuta, M, Carvalho, V, Mira, VL, Pieper, KS, Weber, B, Mota, LH, Peterson, ED, Lopes, RD, and Bridge-Acs Investigators, . "Effect of a multifaceted intervention on use of evidence-based therapies in patients with acute coronary syndromes in Brazil: the BRIDGE-ACS randomized trial." JAMA 307, no. 19 (May 2012): 2041-2049.  Full Text
    • Katz, M, Tarasoutchi, F, Pereira Pesaro, AE, Lopes, RD, Spina, GS, Campos Vieira, ML, and Grinberg, M. "Natriuretic Peptides and Long-Term Mortality in Patients with Severe Aortic Stenosis." JOURNAL OF HEART VALVE DISEASE 21, no. 3 (May 2012): 331-336.  Link to Item
    • Mehta, RH, Kaul, P, Lopes, RD, Patel, MR, Zheng, Y, Pieper, KS, Welsh, RC, Armstrong, PW, and Granger, CB. "Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI) trial." American Heart Journal 163, no. 5 (May 2012): 797-803.  Full Text
    • Suarez, J, Piccini, JP, Liang, L, Atherton, JJ, Hayward, CS, Krum, H, Fonarow, GC, Lopes, RD, and Hernandez, AF. "International variation in use of oral anticoagulation among heart failure patients with atrial fibrillation." Am Heart J 163, no. 5 (May 2012): 804-811.  Full Text  Link to Item
    • Kociol, RD, Lopes, RD, and Patel, MR. "International Variation in Readmission After Myocardial Infarction Reply." JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 307, no. 16 (April 25, 2012): 1691-1691.  Full Text  Link to Item
    • Fosbol, EL, Wang, TY, Li, S, Piccini, JP, Lopes, RD, Shah, B, Mills, RM, Klaskala, W, Alexander, KP, Thomas, L, Roe, MT, and Peterson, ED. "Safety and effectiveness of antithrombotic strategies in older adult patients with atrial fibrillation and non-ST elevation myocardial infarction." American heart journal 163, no. 4 (April 2012): 720-728. (Academic Article)  Full Text
    • Berwanger, O, Guimarães, HP, Laranjeira, LN, Cavalcanti, AB, Kodama, AA, Zazula, AD, Santucci, EV, Victor, E, Tenuta, M, Carvalho, V, Mira, VL, Pieper, KS, Weber, B, Mota, LH, Peterson, ED, Lopes, RD, and for the BRIDGE-ACS Investigators, . "Effect of a Multifaceted Intervention on Use of Evidence-Based Therapies in Patients With Acute Coronary Syndromes in Brazil: The BRIDGE-ACS Randomized Trial." Jama (March 25, 2012).  Full Text  Link to Item
    • Subherwal, S, Peterson, ED, Chen, AY, Roe, MT, Washam, JB, Gage, BF, Bach, RG, Bhatt, DL, Wiviott, SD, Lopes, RD, Alexander, KP, and Wang, TY. "Admission international normalized ratio levels, early treatment strategies, and major bleeding risk among non-ST-segment-elevation myocardial infarction patients on home warfarin therapy: insights from the National Cardiovascular Data Registry." Circulation 125, no. 11 (March 20, 2012): 1414-1423.  Full Text  Link to Item
    • Armaganijan, L, Patel, D, Lopes, RD, Morillo, CA, Arajo, RRN, Munhoz, FP, Puzzi, MA, Carvalho, MJ, Gallo, LBN, and Healey, JS. "Gastroesophageal reflux and atrial fibrillation: Is there any correlation?." Expert Review of Cardiovascular Therapy 10, no. 3 (March 1, 2012): 317-322. (Review)  Full Text
    • Berwanger, O, Guimarães, HP, Laranjeira, LN, Cavalcanti, AB, Kodama, A, Zazula, AD, Santucci, E, Victor, E, Flato, UA, Tenuta, M, Carvalho, V, Mira, VL, Pieper, KS, Mota, LH, Peterson, ED, Lopes, RD, and BRIDGE-ACS, . "A multifaceted intervention to narrow the evidence-based gap in the treatment of acute coronary syndromes: rationale and design of the Brazilian Intervention to Increase Evidence Usage in Acute Coronary Syndromes (BRIDGE-ACS) cluster-randomized trial." American Heart Journal 163, no. 3 (March 2012): 323-329.e1.  Full Text
    • Al-Khatib, SM, Alexander, JH, Lopes, RD, Mahaffey, KW, Patel, MR, and Granger, CB. "Promise of factor Xa inhibition in atrial fibrillation." Curr Cardiol Rep 14, no. 1 (February 2012): 70-78. (Review)  Full Text  Link to Item
    • Lopes, RD, Mehta, RH, Hafley, GE, Williams, JB, Mack, MJ, Peterson, ED, Allen, KB, Harrington, RA, Gibson, CM, Califf, RM, Kouchoukos, NT, Ferguson, TB, Alexander, JH, and Project of Ex Vivo Vein Graft Engineering via Transfection IV (PREVENT IV) Investigators, . "Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery." Circulation 125, no. 6 (February 2012): 749-756.  Full Text
    • Mehta, RH, Stebbins, AS, Lopes, RD, Califf, RM, Pieper, KS, Armstrong, PW, Van de Werf, F, Hochman, JS, White, HD, Topol, EJ, Alexander, JH, and Granger, CB. "Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis." The American Journal of Cardiology 109, no. 3 (February 2012): 320-326.  Full Text
    • Eapen, ZJ, Lopes, RD, Al-Khatib, SM, Wang, Y, Bao, H, Curtis, J, Heidenreich, PA, Hernandez, AF, Peterson, ED, and Hammill, SC. "Erratum: Are racial/ethnic gaps in the use of cardiac resynchronization therapy narrowing? An analysis of 107,096 patients from the national cardiovascular data registrys ICD registry (Journal of the American College of Cardiology (2012) 60(1577-80))." Journal of the American College of Cardiology 60, no. 24 (2012): 2605--.  Full Text
    • Husted, S, James, S, Becker, RC, Horrow, J, Katus, H, Storey, RF, Cannon, CP, Heras, M, Lopes, RD, Morais, J, Mahaffey, KW, Bach, RG, Wojdyla, D, and Wallentin, L. "Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: A substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial." Circulation: Cardiovascular Quality and Outcomes 5, no. 5 (2012): 680-688.  Full Text
    • Kociol, RD, Lopes, RD, Clare, R, Thomas, L, Mehta, RH, Kaul, P, Pieper, KS, Hochman, JS, Weaver, WD, Armstrong, PW, Granger, CB, and Patel, MR. "International variation in and factors associated with hospital readmission after myocardial infarction." Jama 307, no. 1 (January 2012): 66-74.  Full Text
    • Kociol, RD, Lopes, RD, and Patel, MR. "In reply." JAMA - Journal of the American Medical Association 307, no. 16 (2012): 1691--.  Full Text
    • Signori, LU, Quadros, ASD, Sbruzzi, G, Dipp, T, Lopes, RD, and Schaan, BD. "Endothelial function in patients with slow coronary flow and normal coronary angiography." Clinics 67, no. 6 (January 2012): 677-680.  Full Text
    • Lopes, RD, Horowitz, JD, Garcia, DA, Crowther, MA, and Hylek, EM. "Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility." Blood 118, no. 24 (December 8, 2011): 6269-6273.  Full Text  Link to Item
    • Lopes, RD, Shah, BR, Olson, DM, Zhao, X, Pan, W, Bushnell, CD, and Peterson, ED. "Antithrombotic therapy use at discharge and 1 year in patients with atrial fibrillation and acute stroke: results from the AVAIL Registry." Stroke 42, no. 12 (December 2011): 3477-3483.  Full Text
    • Lopes, RD, and Garcia, DA. "In people with atrial fibrillation unsuitable for warfarin, apixaban reduces the risk of stroke compared with aspirin, with no difference in major bleeding." Evid Based Med 16, no. 6 (December 2011): 187-188.  Full Text  Link to Item
    • Cecilia Bahit, M, Lopes, RD, Clare, R, Pieper, KS, Newby, LK, Van de Werf, FF, Armstrong, PW, Mahaffey, KW, Harrington, RA, Ohman, EM, Diaz, R, White, HD, Hernandez, AF, Wallentin, L, Califf, RM, and Granger, CB. "Heart Failure Occurring at any Time During Hospitalization is Associated with Higher Mortality in Non-ST Elevation-Acute Coronary Syndromes." CIRCULATION 124, no. 21 (November 22, 2011).  Link to Item
    • Eapen, Z, Al-Khatib, SM, Wang, Y, Lopes, RD, Bao, H, Curtis, JP, Heidenreich, PA, Hernandez, AF, and Hammill, SC. "Is Cardiac Resynchronization Therapy Use Improving Among Racial/Ethnic Minorities? An Analysis of 107,096 Patients from the NCDR-ICD Registry." CIRCULATION 124, no. 21 (November 22, 2011).  Link to Item
    • Giraldez, RR, Clare, R, Lopes, RD, Dalby, AJ, Prabhakaran, D, Jr, BGX, Giugliano, RP, Tricoci, P, James, SK, Tanguay, J-F, Jr, PCV, Harrington, RA, Braunwald, E, and Newby, LK. "Undiagnosed Diabetes Mellitus, Pre-Diabetes, and Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes." CIRCULATION 124, no. 21 (November 22, 2011).  Link to Item
    • Guptill, JT, Lopes, RD, Mehta, RH, Horton, J, Laskowitz, D, Pieper, KS, Armstrong, PW, and Granger, CB. "Most Strokes Occur More Than 48 Hours Following Primary Percutaneous Coronary Intervention in STEMI: the Stroke Experience in APEX-AMI Trial." CIRCULATION 124, no. 21 (November 22, 2011).  Link to Item
    • Kuijt, WJ, Krucoff, MW, Damman, P, Lopes, RD, Green, CL, Pieper, KS, Stevens, SR, Christenson, RH, Tijssen, JG, Stone, GW, Lincoff, AM, de Winter, RJ, and Roe, MT. "Prediction of Myocardial Infarct Size Using Multiple Concomitant Angiographic, Biochemical and Electrocardiographic Biomarkers in Patients with ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention." CIRCULATION 124, no. 21 (November 22, 2011).  Link to Item
    • Piccini, JP, Holmes, DN, Ollis, DM, Fraulo, ES, Thomas, L, Ansell, JE, Fonarow, GC, Gersh, BJ, Go, AS, Hylek, EM, Kowey, PR, Mahaffey, KW, Lopes, RD, Mills, RM, and Peterson, ED. "Patterns of Atrial Fibrillation and Treatment Strategies Vary According to Provider Specialty Across Community Practice Settings: Findings From the ORBIT-AF Registry." CIRCULATION 124, no. 21 (November 22, 2011).  Link to Item
    • Quadros, AS, Cambruzzi, E, David, R, Sebben, J, Abelin, A, Welter, D, Sarmento-Leite, R, Lopes, RD, and Gottschall, CA. "Red or White Thrombus in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Does it Matter?." CIRCULATION 124, no. 21 (November 22, 2011).  Link to Item
    • Armaganijan, LV, and Lopes, RD. "Antithrombotic therapy in patients with ACS and atrial fibrillation: A challenge in clinical practice." Acute Coronary Syndromes 10, no. 3 (November 17, 2011): 97-102. (Review)
    • Alexander, JH, Lopes, RD, and Wallentin, L. "Apixaban after Acute Coronary Syndrome REPLY." NEW ENGLAND JOURNAL OF MEDICINE 365, no. 19 (November 10, 2011): 1844-1845.  Link to Item
    • Horbach, SJ, Lopes, RD, Guaragna, JCVDC, Martini, F, Mehta, RH, Petracco, JB, Bodanese, LC, Filho, AC, Cirenza, C, de Paola, AAV, and Investigators, NAFARM. "Naproxen as Prophylaxis against Atrial Fibrillation after Cardiac Surgery: The NAFARM Randomized Trial." AMERICAN JOURNAL OF MEDICINE 124, no. 11 (November 2011): 1036-1042.  Full Text  Link to Item
    • Piccini, JP, Fraulo, ES, Ansell, JE, Fonarow, GC, Gersh, BJ, Go, AS, Hylek, EM, Kowey, PR, Mahaffey, KW, Thomas, LE, Kong, MH, Lopes, RD, Mills, RM, and Peterson, ED. "Outcomes registry for better informed treatment of atrial fibrillation: rationale and design of ORBIT-AF." American Heart Journal 162, no. 4 (October 2011): 606-612.e1.  Full Text
    • Lopes, RD, Siha, H, Fu, Y, Mehta, RH, Patel, MR, Armstrong, PW, and Granger, CB. "Diagnosing acute myocardial infarction in patients with left bundle branch block." Am J Cardiol 108, no. 6 (September 15, 2011): 782-788.  Full Text  Link to Item
    • Granger, CB, Alexander, JH, McMurray, JJV, Lopes, RD, Hylek, EM, Hanna, M, Al-Khalidi, HR, Ansell, J, Atar, D, Avezum, A, Bahit, MC, Diaz, R, Easton, JD, Ezekowitz, JA, Flaker, G, Garcia, D, Geraldes, M, Gersh, BJ, Golitsyn, S, Goto, S, Hermosillo, AG, Hohnloser, SH, Horowitz, J, Mohan, P, Jansky, P, Lewis, BS, Lopez-Sendon, JL, Pais, P, Parkhomenko, A, Verheugt, FWA, Zhu, J, Wallentin, L, and ARISTOTLE Committees and Investigators, . "Apixaban versus warfarin in patients with atrial fibrillation." The New England Journal of Medicine 365, no. 11 (September 2011): 981-992.  Full Text
    • Mehta, RH, Honeycutt, E, Patel, UD, Lopes, RD, Williams, JB, Shaw, LK, O'Brien, SM, Califf, RM, Hughes, GC, and Sketch, MH. "Relationship of the time interval between cardiac catheterization and elective coronary artery bypass surgery with postprocedural acute kidney injury." Circulation 124, no. 11 Suppl (September 2011): S149-S155.  Full Text
    • Alexander, JH, Lopes, RD, James, S, Kilaru, R, He, Y, Mohan, P, Bhatt, DL, Goodman, S, Verheugt, FW, Flather, M, Huber, K, Liaw, D, Husted, SE, Lopez-Sendon, J, De Caterina, R, Jansky, P, Darius, H, Vinereanu, D, Cornel, JH, Cools, F, Atar, D, Leiva-Pons, JL, Keltai, M, Ogawa, H, Pais, P, Parkhomenko, A, Ruzyllo, W, Diaz, R, White, H, Ruda, M, Geraldes, M, Lawrence, J, Harrington, RA, Wallentin, L, and APPRAISE-2 Investigators, . "Apixaban with antiplatelet therapy after acute coronary syndrome." The New England Journal of Medicine 365, no. 8 (August 2011): 699-708.  Full Text
    • Lopes, RD, Becker, RC, Alexander, JH, Armstrong, PW, Califf, RM, Chan, MY, Crowther, M, Granger, CB, Harrington, RA, Hylek, EM, James, SK, Jolicoeur, EM, Mahaffey, KW, Newby, LK, Peterson, ED, Pieper, KS, Van de Werf, F, Wallentin, L, White, HD, Carvalho, AC, Giraldez, RR, Guimaraes, HP, Nader, HB, Kalil, RAK, Bizzachi, JMA, Lopes, AC, and Garcia, DA. "Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil." Journal of Thrombosis and Thrombolysis 32, no. 2 (August 2011): 242-266.  Full Text
    • Mehta, RH, Kaul, P, Lopes, RD, Patel, MR, Pieper, KS, Armstrong, PW, and Granger, CB. "Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the APEX-AMI trial." EUROPEAN HEART JOURNAL 32 (August 2011): 872-872.  Link to Item
    • Mehta, RH, Stebbins, A, Lopes, RD, Califf, RM, Alexander, JH, and Granger, CB. "Gender paradox: higher incidence but lower one-year mortality with bleeding among women compared with men following fibrinolysis for acute ST-elevation myocardial infarction." EUROPEAN HEART JOURNAL 32 (August 2011): 166-166.  Link to Item
    • Suarez, J, Piccini, JP, Liang, L, Atherton, JJ, Haywood, CS, Lopes, RD, and Hernandez, AF. "International Variation in Use of Anticoagulation among Heart Failure Patients with Atrial Fibrillation." JOURNAL OF CARDIAC FAILURE 17, no. 8 (August 2011): S72-S72.  Full Text  Link to Item
    • Mehta, RH, Ferguson, TB, Lopes, RD, Hafley, GE, Mack, MJ, Kouchoukos, NT, Gibson, CM, Harrington, RA, Califf, RM, Peterson, ED, Alexander, JH, and Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT) IV Investigators, . "Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV trial." Circulation 124, no. 3 (July 2011): 280-288.  Full Text
    • Leiria, TLL, Lopes, RD, Williams, JB, Katz, JN, Kalil, RAK, and Alexander, JH. "Antithrombotic therapies in patients with prosthetic heart valves: guidelines translated for the clinician." Journal of thrombosis and thrombolysis 31, no. 4 (May 2011): 514-522. (Review)  Full Text
    • Leonardi, S, Thomas, L, Koehler, ML, Tricoci, P, Lopes, RD, White, HD, Armstrong, PW, Newby, LK, and Mahaffey, KW. "WHAT THRESHOLD SHOULD BE USED TO DEFINE PERCUTANEOUS CORONARY INTERVENTION-RELATED MYOCARDIAL INFARCTION? AN APPROACH BASED ON CLINICAL RELEVANCE FROM EARLY ACS AND SYNERGY." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57, no. 14 (April 5, 2011): E1239-E1239.  Full Text  Link to Item
    • Lopes, RD. "Antiplatelet agents in cardiovascular disease." J Thromb Thrombolysis 31, no. 3 (April 2011): 306-309. (Review)  Full Text  Link to Item
    • Mehta, RH, Starr, AZ, Lopes, RD, Piccini, JP, Patel, MR, Pieper, KS, Armstrong, PW, and Granger, CB. "Relationship of sustained ventricular tachyarrhythmias to outcomes in patients undergoing primary percutaneous coronary intervention with varying underlying baseline risk." Am Heart J 161, no. 4 (April 2011): 782-789.  Full Text  Link to Item
    • Gharacholou, SM, Lopes, RD, Alexander, KP, Mehta, RH, Stebbins, AL, Pieper, KS, James, SK, Armstrong, PW, and Granger, CB. "Age and outcomes in ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: findings from the APEX-AMI trial." Archives of Internal Medicine 171, no. 6 (March 2011): 559-567.  Full Text
    • Quadros, AS, Welter, DI, Camozzatto, FO, Chaves, A, Mehta, RH, Gottschall, CA, and Lopes, RD. "Identifying patients at risk for premature discontinuation of thienopyridine after coronary stent implantation." Am J Cardiol 107, no. 5 (March 1, 2011): 685-689.  Full Text  Link to Item
    • Alexander, JH, Lopes, RD, and Wallentin, L. "The authors reply." New England Journal of Medicine 365, no. 19 (2011): 1844-1845.  Full Text
    • Armaganijan, L, Lopes, RD, Healey, JS, Piccini, JP, Nair, GM, and Morillo, CA. "Do omega-3 fatty acids prevent atrial fibrillation after open heart surgery? A meta-analysis of randomized controlled trials." Clinics (Sao Paulo, Brazil) 66, no. 11 (January 2011): 1923-1928. (Review)  Full Text
    • Gualandro, DM, Yu, PC, Calderaro, D, Marques, AC, Pinho, C, Caramelli, B, Feitosa, ACR, Ayub, B, Polanczyk, CA, Jardim, C, Vieira, CLZ, lezzi, D, Ikeoka, DT, Schreen, D, D'Amico, EA, Pfeferman, E, de Lima, EQ, Burdmann, EDA, Pachon, E, Machado, FS, Galas, FRBG, Paula, FJD, Carvalho, FCD, Feitosa-Filho, GS, Prado, GF, Lopes, HF, Lima, JJGD, Marchini, JFM, Fornari, LS, Drager, LF, Vacanti, LJ, Hajjar, LA, Rohde, LEP, Gowdak, LH, Cardoso, LF, Vieira, MLC, Monachini, MC, Macatrão, M, and Villaça, PR et al. "II Guidelines for perioperative evaluation of the Brazilian Society of Cardiology." Arquivos brasileiros de cardiologia 96, no. 3 Suppl 1 (January 2011): 1-68.  Full Text
    • Mehta, RH, Stebbins, A, Lopes, RD, Rao, SV, Bates, ER, Pieper, KS, Armstrong, PW, Van de Werf, F, White, HD, Califf, RM, Alexander, JH, and Granger, CB. "Race, Bleeding, and Outcomes in STEMI Patients Treated with Fibrinolytic Therapy." The American Journal of Medicine 124, no. 1 (January 2011): 48-57.  Full Text
    • Stashenko, G, Lopes, RD, Garcia, D, Alexander, JH, and Tapson, VF. "Prophylaxis for venous thromboembolism: guidelines translated for the clinician." J Thromb Thrombolysis 31, no. 1 (January 2011): 122-132. (Review)  Full Text  Link to Item
    • Chan, MY, Sun, JL, Wang, TY, Lopes, RD, Jolicoeur, ME, Pieper, KS, Rao, SV, Newby, LK, Mahaffey, KW, Harrington, RA, and Peterson, ED. "Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: a pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY." American Heart Journal 160, no. 6 (December 2010): 1056-1064.e2.  Full Text
    • Garcia, DA, Lopes, RD, and Hylek, EM. "New-onset atrial fibrillation and warfarin initiation: high risk periods and implications for new antithrombotic drugs." Thromb Haemost 104, no. 6 (December 2010): 1099-1105. (Review)  Full Text  Link to Item
    • Mehta, RH, Honeycutt, E, Patel, UD, Lopes, RD, Shaw, LK, Glower, DD, Harrington, RA, Califf, RM, and Sketch, MH. "Impact of recovery of renal function on long-term mortality after coronary artery bypass grafting." The American Journal of Cardiology 106, no. 12 (December 2010): 1728-1734.  Full Text
    • Leonardi, S, Stebbins, A, Lopes, RD, Lokhnygina, Y, Bhatt, DL, Stone, GW, Lincoff, MA, Dauerman, HL, Gibson, CM, White, HD, Parick, K, Gruberg, L, Herrmann, HC, McLaurin, BT, Goodman, S, Harrington, RA, and Mahaffey, KW. "Pre-Treatment With Thienopyridines Reduces The Amount of Myonecrosis in Acute Coronary Syndrome Patients Invasively Managed: Insights from the CHAMPION trials." CIRCULATION 122, no. 21 (November 23, 2010).  Link to Item
    • Lopes, RD, Li, L, Granger, CB, Wang, TY, Foody, JM, Funk, M, Peterson, ED, and Alexander, KP. "Discharge Warfarin is Underused in High Risk Atrial Fibrillation Patients With Myocardial Infarction." CIRCULATION 122, no. 21 (November 23, 2010).  Link to Item
    • Lopes, RD, White, JA, Tricoci, P, White, HD, Armstrong, PW, Braunwald, E, Giugliano, RP, Harrington, RA, Lewis, BS, Brogan, GX, Gibson, CM, and Newby, LK. "More Bleeding but No Additional Efficacy with Increasing Age in High-risk ACS Patients Treated with Early vs. Delayed, Provisional Eptifibatide." CIRCULATION 122, no. 21 (November 23, 2010).  Link to Item
    • Kong, MH, Lopes, RD, Piccini, JP, Hasselblad, V, Bahnson, TD, and Al-Khatib, SM. "Surgical Maze procedure as a treatment for atrial fibrillation: a meta-analysis of randomized controlled trials." Cardiovasc Ther 28, no. 5 (October 2010): 311-326. (Review)  Full Text  Link to Item
    • Flato, UAP, Guimarães, HP, Lopes, RD, Valiatti, JL, Flato, EMS, and Lorenzo, RG. "Usefulness of Extended-FAST (EFAST-Extended Focused Assessment with Sonography for Trauma) in critical care setting." Revista Brasileira de terapia intensiva 22, no. 3 (September 2010): 291-299.
    • Piccini, JP, Lopes, RD, and Mahaffey, KW. "Oral factor Xa inhibitors for the prevention of stroke in atrial fibrillation." Curr Opin Cardiol 25, no. 4 (July 2010): 312-320. (Review)  Full Text  Link to Item
    • van Diepen, S, Siha, H, Fu, Y, Westerhout, CM, Lopes, RD, Granger, CB, Armstrong, PW, and APEX AMI Investigators, . "Do baseline atrial electrocardiographic and infarction patterns predict new-onset atrial fibrillation after ST-elevation myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction Trial." Journal of Electrocardiology 43, no. 4 (July 2010): 351-358.  Full Text
    • Lopes, RD, Peterson, ED, Chen, AY, Roe, MT, Wang, TY, Ohman, EM, Magid, DJ, Ho, PM, Wiviott, SD, Scirica, BM, and Alexander, KP. "Antithrombotic strategy in non-ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: insights from the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry." JACC Cardiovasc Interv 3, no. 6 (June 2010): 669-677.  Full Text  Link to Item
    • Gharacholou, SM, Lopes, RD, Washam, JB, Newby, LK, James, SK, and Alexander, JH. "Antithrombotic therapy in acute coronary syndromes: guidelines translated for the clinician." J Thromb Thrombolysis 29, no. 4 (May 2010): 516-528. (Review)  Full Text  Link to Item
    • Lopes, RD, Garcia, D, Becker, RC, Granger, CB, Newby, LK, Alexander, JH, Jolicoeur, EM, Handler, A, Pieper, KS, Carvalho, AC, Guimaraes, HP, Chamone, DAF, Baruzzi, AC, Machado, FS, Timerman, A, and Lopes, AC. "Highlights from the II International Symposium of Thrombosis and Anticoagulation (ISTA), October 22-23, 2009, São Paulo, Brazil." J Thromb Thrombolysis 29, no. 4 (May 2010): 395-408.  Full Text  Link to Item
    • Krishnan, A, Lopes, RD, Alexander, JH, Becker, RC, and Goldstein, LB. "Antithrombotic therapy for ischemic stroke: guidelines translated for the clinician." J Thromb Thrombolysis 29, no. 3 (April 2010): 368-377. (Review)  Full Text  Link to Item
    • Lopes, RD, Alexander, JH, Al-Khatib, SM, Ansell, J, Diaz, R, Easton, JD, Gersh, BJ, Granger, CB, Hanna, M, Horowitz, J, Hylek, EM, McMurray, JJV, Verheugt, FWA, Wallentin, L, and ARISTOTLE Investigators, . "Apixaban for reduction in stroke and other ThromboemboLic events in atrial fibrillation (ARISTOTLE) trial: design and rationale." American Heart Journal 159, no. 3 (March 2010): 331-339.  Full Text
    • Lopes, RD, Batista, ML, Rosa, JC, Lira, FSD, Martins, E, Shimura, AY, Brum, PC, Lancha, AH, Seelaender, MCL, and Lopes, AC. "Changes in the production of IL-10 and TNF-alpha in skeletal muscle of rats with heart failure secondary to acute myocardial infarction." Arq Bras Cardiol 94, no. 3 (March 2010): 293-320.  Link to Item
    • Lopes, RD, Starr, A, Pieper, CF, Al-Khatib, SM, Newby, LK, Mehta, RH, Van de Werf, F, Mahaffey, KW, Armstrong, PW, Harrington, RA, White, HD, Wallentin, L, and Granger, CB. "Warfarin use and outcomes in patients with atrial fibrillation complicating acute coronary syndromes." Am J Med 123, no. 2 (February 2010): 134-140.  Full Text  Link to Item
    • Batista, ML, Rosa, JC, Lopes, RD, Lira, FS, Martins, E, Yamashita, AS, Brum, PC, Lancha, AH, Lopes, AC, and Seelaender, M. "Exercise training changes IL-10/TNF-alpha ratio in the skeletal muscle of post-MI rats." Cytokine 49, no. 1 (January 2010): 102-108.  Full Text
    • Gomes, CBG, and Veras, GJ. "Strain bidimensional na cardiopatia de Takotsubo." Arquivos Brasileiros de Cardiologia 95, no. 2 (2010): e35-e37.  Full Text
    • Lopes, RD, and Granger, CB. "Interpreting the TRITON results in light of the event adjudication process." Cardiology 115, no. 2 (2010): 89-90.  Full Text  Link to Item
    • Mehta, RH, Lopes, RD, Ballotta, A, Frigiola, A, Sketch, MH, Bossone, E, and Bates, ER. "Percutaneous coronary intervention or coronary artery bypass surgery for cardiogenic shock and multivessel coronary artery disease?." Am Heart J 159, no. 1 (January 2010): 141-147. (Review)  Full Text  Link to Item
    • Ávila, MS, Dalmaschio, AC, and Benvenuti, LA. "Caso 4: Mulher de 77 Anos com insuficiência cardíaca, função sistólica normal do ventrículo esquerdo e sinais de cardiopatia restritiva." Arquivos Brasileiros de Cardiologia 95, no. 2 (2010): 27-34.  Full Text
    • Batista, ML, Lopes, RD, Seelaender, MCL, and Lopes, AC. "Anti-inflammatory effect of physical training in heart failure: role of TNF-alpha and IL-10." Arq Bras Cardiol 93, no. 6 (December 2009): 643-700. (Review)  Link to Item
    • Júnior, MLB, Lopes, RD, Seelaender, MCL, and Lopes, AC. "Antiinflammatory effect of physical training in heart failure: Role of TNF-α and IL-10." Arquivos Brasileiros de Cardiologia 93, no. 6 (December 1, 2009). (Review)
    • Piccini, JP, Lopes, RD, Kong, MH, Hasselblad, V, Jackson, K, and Al-Khatib, SM. "Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials." Circulation. Arrhythmia and Electrophysiology 2, no. 6 (December 2009): 626-633.  Full Text
    • Lopes, RD, Alexander, JH, and Ferguson, TB. "The authors reply." New England Journal of Medicine 361, no. 19 (November 5, 2009): 1909-1910. (Letter)  Open Access Copy
    • Lopes, RD, Alexander, JH, and Ferguson, TB. "Endoscopic versus Open Vein-Graft Harvesting REPLY." NEW ENGLAND JOURNAL OF MEDICINE 361, no. 19 (November 5, 2009): 1909-1910.  Link to Item
    • Lopes, RD, Ohman, EM, Granger, CB, Honeycutt, EF, Anstrom, KJ, Berger, PB, Crespo, EM, Oliveira, GBF, Moll, S, Moliterno, DJ, Abrams, CS, and Becker, RC. "Six-month follow-up of patients with in-hospital thrombocytopenia during heparin-based anticoagulation (from the Complications After Thrombocytopenia Caused by Heparin [CATCH] registry)." Am J Cardiol 104, no. 9 (November 1, 2009): 1285-1291.  Full Text  Link to Item
    • Houman Fekrazad, M, Lopes, RD, Stashenko, GJ, Alexander, JH, and Garcia, D. "Treatment of venous thromboembolism: guidelines translated for the clinician." J Thromb Thrombolysis 28, no. 3 (October 2009): 270-275.  Full Text  Link to Item
    • Lopes, RD, Jolicoeur, EM, and Chan, MY. "Hyporesponsivity to antiplatelet therapy." Revista Brasileira de Cardiologia Invasiva 17, no. 4 (October 1, 2009): 450-452.
    • Lopes, RD, and Alexander, KP. "Antiplatelet therapy in older adults with non-ST-segment elevation acute coronary syndrome: considering risks and benefits." Am J Cardiol 104, no. 5 Suppl (September 7, 2009): 16C-21C. (Review)  Full Text  Link to Item
    • Lopes, RD, Elliott, LE, White, HD, Hochman, JS, Van de Werf, F, Ardissino, D, Nielsen, TT, Weaver, WD, Widimsky, P, Armstrong, PW, and Granger, CB. "Antithrombotic therapy and outcomes of patients with atrial fibrillation following primary percutaneous coronary intervention: results from the APEX-AMI trial." Eur Heart J 30, no. 16 (August 2009): 2019-2028.  Full Text  Link to Item
    • Kraai, EP, Lopes, RD, Alexander, JH, and Garcia, D. "Perioperative management of anticoagulation: guidelines translated for the clinician." J Thromb Thrombolysis 28, no. 1 (July 2009): 16-22. (Review)  Full Text  Link to Item
    • Lopes, RD, Becker, RC, Garcia, D, Hylek, EM, Granger, CB, Lourenço, DM, Nader, HB, Maffei, FHA, Cesena, FHY, Nicolau, JC, Timmerman, A, Rocha, AT, de Paiva, EF, Guimaraes, HP, Carvalho, AC, D'Amico, EA, Moreira-Filho, CA, Aldrighi, JM, and Lopes, AC. "Highlights from the I international symposium of thrombosis and anticoagulation in internal medicine, October 23-25, 2008, Sao Paulo, Brazil." J Thromb Thrombolysis 28, no. 1 (July 2009): 106-116. (Review)  Full Text  Link to Item
    • Lopes, RD, Hafley, GE, Allen, KB, Ferguson, TB, Peterson, ED, Harrington, RA, Mehta, RH, Gibson, CM, Mack, MJ, Kouchoukos, NT, Califf, RM, and Alexander, JH. "Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery." The New England Journal of Medicine 361, no. 3 (July 2009): 235-244.  Full Text
    • Mehta, RH, Starr, AZ, Lopes, RD, Hochman, JS, Widimsky, P, Pieper, KS, Armstrong, PW, Granger, CB, and APEX AMI Investigators, . "Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention." JAMA 301, no. 17 (May 6, 2009): 1779-1789.  Full Text  Link to Item
    • Kong, MH, Lopes, RD, Piccini, JP, Hasselblad, V, Bahnson, TD, and Al-Khatib, SM. "Surgical Maze Procedure as a Treatment for Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53, no. 10 (March 10, 2009): A118-A118.  Link to Item
    • Lopes, RD, Siha, H, Fu, Y, Armstrong, PW, and Granger, CB. "Left Bundle Branch Block Without Concordant ST-Elevation In Suspected ST-Elevation Myocardial Infarction Identifies Patients With High False Positive Rates: Insights From the APEX-AMI Trial." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53, no. 10 (March 10, 2009): A323-A323.  Link to Item
    • Lopes, RD, Starr, A, Al-Khatib, SM, Newby, LK, Mehta, RH, de Werf, FV, Mahaffey, KW, Armstrong, PW, Harrington, RA, White, HD, Wallentin, L, and Granger, CB. "Warfarin Is Independently Associated With Lower Risk of Six-Month Death or Myocardial Infarction in Patients With Atrial Fibrillation Following Acute Coronary Syndromes." JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53, no. 10 (March 10, 2009): A354-A354.  Link to Item
    • Feitosa-Filho, GS, Sena, JP, Guimarães, HP, and Lopes, RD. "Therapeutical hypothermia after cardiopulmonary resuscitation: evidences and practical issues." Revista Brasileira de terapia intensiva 21, no. 1 (March 2009): 65-71.
    • Lira, FS, Rosa, JC, Zanchi, NE, Yamashita, AS, Lopes, RD, Lopes, AC, Batista, ML, and Seelaender, M. "Regulation of inflammation in the adipose tissue in cancer cachexia: effect of exercise." Cell Biochem Funct 27, no. 2 (March 2009): 71-75. (Review)  Full Text  Link to Item
    • Lopes, RD, Alexander, KP, Manoukian, SV, Bertrand, ME, Feit, F, White, HD, Pollack, CV, Hoekstra, J, Gersh, BJ, Stone, GW, and Ohman, EM. "Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial." Journal of the American College of Cardiology 53, no. 12 (March 2009): 1021-1030.  Full Text
    • Belfort, RN, Fernandes, BF, Romano, A, Nose, R, Cools-Lartigue, J, Navajas, EV, Vieira, GM, Lopes, RD, and Belfort, R. "Bilateral macular hemorrhage as a complication of drug-induced anemia: a case report. (Published online)" J Med Case Rep 3 (January 13, 2009): 16-.  Full Text  Link to Item
    • Lópes, RD, Chan, M, and Newby, LK. "Novel Markers in Patients with Suspected Acute Coronary Syndromes." (January 13, 2009): 75-92. (Chapter)  Full Text
    • Lopes, RD, and Granger, CB. "β-blockers in myocardial infarction: An overview." Acute Coronary Syndromes 9, no. 4 (2009): 141-147.
    • Lopes, RD, and Granger, CB. "Highlights from the American Heart Association (AHA) Scientific Sessions 2008." Acute Coronary Syndromes 9, no. 3 (2009): 121-124.
    • Lopes, RD, Piccini, JP, Hylek, EM, Granger, CB, and Alexander, JH. "Antithrombotic therapy in atrial fibrillation: guidelines translated for the clinician." J Thromb Thrombolysis 26, no. 3 (December 2008): 167-174. (Review)  Full Text  Link to Item
    • Lopes, RD, Granger, CB, Honeycutt, EF, Crespo, EM, Anstrom, KJ, Ohman, EM, and Becker, RC. "Patients with Thrombocytopenia following Heparin Therapy Have Early but not Late Risk of Death: Results from the CATCH Registry." CIRCULATION 118, no. 18 (October 28, 2008): S1052-S1052.  Link to Item
    • Mehta, RH, Starr, AZ, Lopes, RD, Pieper, KS, Armstrong, PW, Granger, CB, and Investigators, APEX-AMIT. "Association of Sustained Ventricular Tachycardia/Fibrillation and the Timing of its Occurrence on Outcomes in Patients Undergoing Primary Percutaneous Coronary Interventions: Insights from the APEX-AMI Trial." CIRCULATION 118, no. 18 (October 28, 2008): S1058-S1058.  Link to Item
    • Lopes, RD, Hafley, GE, Allen, KB, Ferguson, TB, Peterson, ED, Harrington, RA, Kouchoukos, NT, Gibson, CM, Alexander, JH, and Investigators, PREVENT-IV. "Endoscopic vein harvesting is a strong independent predictor of vein graft failure in patients undergoing coronary artery bypass graft surgery." EUROPEAN HEART JOURNAL 29 (September 2008): 284-285.  Link to Item
    • Lopes, RD, Alexander, KP, Marcucci, G, White, HD, Spinler, S, Col, J, Aylward, PE, Califf, RM, and Mahaffey, KW. "Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial." European Heart Journal 29, no. 15 (August 2008): 1827-1833.  Full Text
    • Lopes, RD, Pieper, KS, Horton, JR, Al-Khatib, SM, Newby, LK, Mehta, RH, Van de Werf, F, Armstrong, PW, Mahaffey, KW, Harrington, RA, Ohman, EM, White, HD, Wallentin, L, and Granger, CB. "Short- and long-term outcomes following atrial fibrillation in patients with acute coronary syndromes with or without ST-segment elevation." Heart 94, no. 7 (July 2008): 867-873.  Full Text  Link to Item
    • Batista, MD, Takano, D, Lopes, RD, Enokihara, MMSS, Michalany, NS, and de Almeida, FA. "Paraneoplastic pemphigus associated with non-Hodgkin lymphoma. (Published online)" Dermatol Online J 14, no. 6 (June 15, 2008): 11-.  Link to Item
    • Allen, LA, Jolicoeur, EM, Melloni, C, Lopes, RD, Chan, MY, Majidi, M, Piccini, JP, Berger, JS, Katz, JN, and Shah, BR. "Highlights from American Heart Association, November 4-7, 2007, Orlando, Florida, USA. Late-breaking trials summary." American heart journal 155, no. 4 (April 2008): 615-623. (Academic Article)  Full Text
    • Batista, ML, Santos, RVT, Lopes, RD, Lopes, AC, Costa Rosa, LFBP, and Seelaender, MCL. "Endurance training modulates lymphocyte function in rats with post-MI CHF." Med Sci Sports Exerc 40, no. 3 (March 2008): 549-556.  Full Text  Link to Item
    • Lopes, RD, Chan, M, Melloni, C, Jolicoeur, EM, Allen, LA, Shah, BR, Katz, JN, Berger, JS, and Piccini, JP. "Late-breaking trials summary from the 2008 American College of Cardiology Scientific Sessions, March 29 to April 1, Chicago, IL." American Heart Journal 156, no. 1 (2008): 7-12.  Full Text
    • Lopes, RD, Mahaffey, K, Harrington, RA, Horton, J, Armstrong, P, Newby, K, Ohman, M, De Werf, FV, Al-Khatib, SM, Wallentin, L, and Granger, CB. "Atrial fibrillation is independently associated with a high risk of death in patients with acute coronary syndromes." CIRCULATION 116, no. 16 (October 16, 2007): 315-315.  Link to Item
    • Jolicoeur, EM, Wang, T, Lopes, RD, and Ohman, EM. "Percutaneous coronary interventions in patients with heparin-induced thrombocytopenia." Curr Cardiol Rep 9, no. 5 (September 2007): 396-405. (Review)  Link to Item
    • Lopes, RD, Mahaffey, KM, Harrington, RH, Lan, LL, Armstrong, PA, Newby, KN, Ohman, MO, Van de Werf, FVW, Al-Khatib, SAK, and Granger, CBG. "Atrial fibrillation is associated with worse outcomes in ST elevation and non ST elevation acute coronary syndromes." EUROPEAN HEART JOURNAL 28 (September 2007): 259-260.  Link to Item
    • Lopes, RD, Marcucci, G, White, HD, Spinler, SA, Col, J, Gulba, DC, Aylward, PE, Califf, RM, Ferguson, JJ, and Mahaffey, KW. "Similar association between age and outcomes in high-risk ACS patients treated with enoxaparin or unfractionated heparin." EUROPEAN HEART JOURNAL 28 (September 2007): 218-218.  Link to Item
    • Adams, GL, Mills, JS, Melloni, C, Allen, LA, Jolicoeur, EM, Wang, T, Chan, M, Majidi, M, and Lopes, RD. "Highlights from the 56th annual scientific sessions of the American College of Cardiology: March 25 to 27, 2007, Atlanta, Georgia." Am Heart J 154, no. 2 (August 2007): 247-259.  Full Text  Link to Item
    • Lopes, RD, Neves, LB, D'Almeida, V, Conceição, GMDS, and Gabriel, A. "Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus." Arq Bras Cardiol 88, no. 4 (April 2007): 424-429.  Link to Item
    • Lopes, RD, Neves, LB, D'Almeida, V, Conceição, GMDS, and Jr, AG. "Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus." Arquivos Brasileiros de Cardiologia 88, no. 4 (2007): 373-377+424-429-.
    • Hira, AY, Nebel de Mello, A, Faria, RA, Odone Filho, V, Lopes, RD, and Zuffo, MK. "Development of a telemedicine model for emerging countries: a case study on pediatric oncology in Brazil." Conf Proc IEEE Eng Med Biol Soc 1 (2006): 5252-5256.  Full Text  Link to Item
    • Santos, IS, Boccio, J, Santos, AS, Valle, NCJ, Halal, CS, Bachilli, MC, and Lopes, RD. "Prevalence of Helicobacter pylori infection and associated factors among adults in Southern Brazil: a population-based cross-sectional study. (Published online)" BMC Public Health 5 (November 10, 2005): 118-.  Full Text  Link to Item
    • Góes, VP, Machado, LS, Cabral, MC, Leitão, RB, Lopes, RD, and Zuffo, MK. "Interactive stereoscopic full-color direct volume visualization for virtual reality applications in medicine." Stud Health Technol Inform 81 (2001): 161-167.  Link to Item
    • Machado, LS, de Mello, AN, Lopes, RD, Odone Filho, V, and Zuffo, MK. "A virtual reality simulator for bone marrow harvest for pediatric transplant." Stud Health Technol Inform 81 (2001): 293-297.  Link to Item
    • Liberatori Filho, AW, Lopes, RD, Mora, OA, Simões, MJ, and Lopes, AC. "[Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats]." Rev Assoc Med Bras (1992) 45, no. 3 (July 1999): 242-246.  Link to Item

  • Other Articles

    • Castleberry, AW, Williams, JB, Daneshmand, MA, Honeycutt, E, Shaw, LK, Samad, Z, Lopes, RD, Alexander, JH, Mathew, JP, Velazquez, EJ, Milano, CA, and Smith, PK. "Response to letter regarding article, "surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience"." Circulation 131, no. 11 (March 2015): e378-e379. (Letter)  Full Text

  • Reports

    • Al-Khatib, SM, Allen LaPointe, N, Chatterjee, R, Crowley, MJ, Dupre, ME, Kong, DF, Lopes, RD, Povsic, TJ, Raju, SS, Kosinski, A, McBroom, AJ, Chobot, MM, Gray, R, and Sanders, GD. Treatment of Atrial Fibrillation. Comparative Effectiveness Review 119. Rockville, MD: AHRQ Publication, June 28, 2013.

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