Skip to main content

Robert J Edwards

Associate Professor in Medicine
Medicine, Duke Human Vaccine Institute
Box 103020 DUMC, Durham, NC 27710
LSRC Bldg, Rm A06, 308 Research Drive, Durham, NC 27710

Current Appointments & Affiliations


Associate Professor in Medicine · 2021 - Present Medicine, Duke Human Vaccine Institute, Medicine
Member of the Duke Human Vaccine Institute · 2017 - Present Duke Human Vaccine Institute, Institutes and Centers

Recent Publications


Myosin S2 origins track evolution of strong binding on actin by azimuthal rolling of motor domain.

Journal Article Biophys J · March 24, 2015 Myosin crystal structures have given rise to the swinging lever arm hypothesis, which predicts a large axial tilt of the lever arm domain during the actin-attached working stroke. Previous work imaging the working stroke in actively contracting, fast-froze ... Full text Link to item Cite

Structural changes in isometrically contracting insect flight muscle trapped following a mechanical perturbation.

Journal Article PLoS One · 2012 The application of rapidly applied length steps to actively contracting muscle is a classic method for synchronizing the response of myosin cross-bridges so that the average response of the ensemble can be measured. Alternatively, electron tomography (ET) ... Full text Link to item Cite
View All Publications

Recent Grants


Neonatal Immunity to novel TF SHIVs

ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2029

SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimens

ResearchInvestigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

SHIV/HIV Env-Antibody Coevolution as a Guide to Iterative Vaccine Design

ResearchCollaborator · Awarded by University of Pennsylvania · 2017 - 2027

View All Grants

Education, Training & Certifications


Duke University · 1998 Ph.D.