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Roarke Horstmeyer

Assistant Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, Durham, NC 27708-0548
Fitzpatrick Center (CIEMAS) Room 2569, 101 Science Drive, Durham, NC 27701

Overview


Roarke Horstmeyer is an assistant professor within Duke's Biomedical Engineering Department. He develops microscopes, cameras and computer algorithms for a wide range of applications, from forming 3D reconstructions of organisms to detecting neural activity deep within tissue. His areas of interest include optics, signal processing, optimization and neuroscience. Most recently, Dr. Horstmeyer was a guest professor at the University of Erlangen in Germany and an Einstein postdoctoral fellow at Charitè Medical School in Berlin. Prior to his time in Germany, Dr. Horstmeyer earned a PhD from Caltech’s electrical engineering department in 2016, a master of science degree from the MIT Media Lab in 2011, and a bachelors degree in physics and Japanese from Duke University in 2006.

Office Hours


Office hours for Fall 2020 - Spring 2021:

Wednesdays 10-11:30am 
Thursdays 10am - 11:30am

Current Appointments & Affiliations


Assistant Professor of Biomedical Engineering · 2018 - Present Biomedical Engineering, Pratt School of Engineering
Faculty Network Member of the Duke Institute for Brain Sciences · 2018 - Present Duke Institute for Brain Sciences, University Institutes and Centers

In the News


Published October 30, 2024
Is Social Media Friend or Foe for Faculty? Or Both?
Published January 30, 2024
A Marriage of AI and Photonics to Advance Imaging, Health Care and Public Safety
Published December 14, 2022
Invented at Duke Connects University's Research, Innovation and Entrepreneurship Communities

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Recent Publications


Beneath the surface: revealing deep-tissue blood flow in human subjects with massively parallelized diffuse correlation spectroscopy.

Journal Article Neurophotonics · April 2025 SignificanceDiffuse correlation spectroscopy (DCS) allows label-free, non-invasive investigation of microvascular dynamics deep within tissue, such as cerebral blood flow (CBF). However, the signal-to-noise ratio (SNR) in DCS limits its effective ... Full text Open Access Cite

Recording dynamic facial micro-expressions with a multi-focus camera array.

Journal Article Biomedical optics express · February 2025 We present a multi-camera array for capturing dynamic high-resolution videos of the human face. Compared to traditional single-camera configurations, our array of 54 individual cameras allows stitching of high-resolution composite video frames (709 megapix ... Full text Open Access Cite

Computational 3D topographic microscopy from terabytes of data per sample

Journal Article Journal of Big Data · December 1, 2024 We present a large-scale computational 3D topographic microscope that enables 6-gigapixel profilometric 3D imaging at micron-scale resolution across >110 cm2 areas over multi-millimeter axial ranges. Our computational microscope, termed STARCAM (Scanning T ... Full text Cite
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Recent Grants


Large area high resolution in vitro pathology

ResearchPrincipal Investigator · Awarded by Rice University · 2024 - 2029

CAREER: Multi-aperture 3D microscopy for cellular-scale measurement over macroscopic volumes

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2023 - 2028

Optical interrogation of deep-brain activity via parallelized diffuse correlation spectroscopy

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2024 - 2027

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Education, Training & Certifications


California Institute of Technology · 2016 Ph.D.
Duke University · 2006 B.S.